#=GF ID   Peroxin-22
#=GF AC   PF12827.11
#=GF DE   Peroxisomal biogenesis protein family
#=GF AU   Wood V;0000-0001-6330-7526
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Pfam-B_15020 (release 24.0)
#=GF GA   26.00 26.00;
#=GF TC   26.50 27.30;
#=GF NC   24.90 25.50;
#=GF BM   hmmbuild  --aminoHMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10402463
#=GF RT   Pex22p of Pichia pastoris, essential for peroxisomal matrix
#=GF RT   protein import, anchors the ubiquitin-conjugating enzyme, Pex4p,
#=GF RT   on the peroxisomal membrane.
#=GF RA   Koller A, Snyder WB, Faber KN, Wenzel TJ, Rangell L, Keller GA,
#=GF RA   Subramani S;
#=GF RL   J Cell Biol. 1999;146:99-112.
#=GF RN   [2]
#=GF RM   23896733
#=GF RT   A disulphide bond in the E2 enzyme Pex4p modulates
#=GF RT   ubiquitin-conjugating activity.
#=GF RA   Williams C, van den Berg M, Stanley WA, Wilmanns M, Distel B;
#=GF RL   Sci Rep. 2013;3:2212.
#=GF RN   [3]
#=GF RM   22085930
#=GF RT   Insights into ubiquitin-conjugating enzyme/ co-activator
#=GF RT   interactions from the structure of the Pex4p:Pex22p complex.
#=GF RA   Williams C, van den Berg M, Panjikar S, Stanley WA, Distel B,
#=GF RA   Wilmanns M;
#=GF RL   EMBO J. 2012;31:391-402.
#=GF RN   [4]
#=GF RM   29288668
#=GF RT   Structural insights into K48-linked ubiquitin chain formation by
#=GF RT   the Pex4p-Pex22p complex.
#=GF RA   Groves MR, Schroer CFE, Middleton AJ, Lunev S, Danda N, Ali AM,
#=GF RA   Marrink SJ, Williams C;
#=GF RL   Biochem Biophys Res Commun. 2018;496:562-567.
#=GF DR   INTERPRO; IPR024359;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Peroxin-22 is a integral peroxisomal membrane protein family.
#=GF CC   The N-terminus is in the matrix and the C-terminus is in the
#=GF CC   cytosol. The N-terminus carries a 25-amino acid peroxisome
#=GF CC   membrane-targeting signal. It interacts with the
#=GF CC   ubiquitin-conjugating peripheral peroxisomal membrane enzyme
#=GF CC   Pex4p anchoring it at the peroxisomal membrane. Both Pex
#=GF CC   proteins are involved at the same stage of peroxisome biogenesis
#=GF CC   [1]. Pex22p-Pex4p interaction is required for ubiquitination of
#=GF CC   peroxisomal import receptor Pex5p mediated by Pex4p [2-4].
#=GF SQ   70
#=GS A0A1S7H7X3_9SACH/43-148   AC A0A1S7H7X3.1
#=GS A0A1E4S0X4_CYBJN/43-151   AC A0A1E4S0X4.1
#=GS PEX22_DEBHA/56-178        AC Q6BMZ7.1
#=GS A5DX24_LODEL/91-216       AC A5DX24.1
#=GS C4R500_KOMPG/42-169       AC C4R500.1
#=GS A0A8H7GVJ0_9ASCO/45-164   AC A0A8H7GVJ0.1
#=GS A0A1E4SMA5_9ASCO/39-154   AC A0A1E4SMA5.1
#=GS A0A448YFZ5_BRENA/59-183   AC A0A448YFZ5.1
#=GS Q6C2P3_YARLI/51-160       AC Q6C2P3.2
#=GS K0KTQ5_WICCF/53-159       AC K0KTQ5.1
#=GS G3B2E7_CANTC/39-159       AC G3B2E7.1
#=GS A0A1E4SUI1_9ASCO/42-155   AC A0A1E4SUI1.1
#=GS A0A8H7USX0_9FUNG/132-237  AC A0A8H7USX0.1
#=GS A0A642V024_DIURU/52-170   AC A0A642V024.1
#=GS G3AL82_SPAPN/52-160       AC G3AL82.1
#=GS A0A421JUW2_9ASCO/56-164   AC A0A421JUW2.1
#=GS H2ASY6_KAZAF/54-162       AC H2ASY6.1
#=GS A0A1G4IQA8_9SACH/39-139   AC A0A1G4IQA8.1
#=GS G8BWQ5_TETPH/49-156       AC G8BWQ5.1
#=GS A3LVY4_PICST/56-171       AC A3LVY4.2
#=GS A0A1V2L9Y6_CYBFA/42-135   AC A0A1V2L9Y6.1
#=GS W1QAA3_OGAPD/42-152       AC W1QAA3.1
#=GS A0A7H9HZ38_9SACH/36-134   AC A0A7H9HZ38.1
#=GS C4Y073_CLAL4/43-162       AC C4Y073.1
#=GS A0A4T0X754_9ASCO/56-175   AC A0A4T0X754.1
#=GS A0A2V1ASA9_9ASCO/35-154   AC A0A2V1ASA9.1
#=GS A0A367YMM0_9ASCO/53-162   AC A0A367YMM0.1
#=GS I6NCM2_ERECY/37-142       AC I6NCM2.1
#=GS C5M7G2_CANTT/51-160       AC C5M7G2.1
#=GS A0A8J5UEU4_9ASCO/31-139   AC A0A8J5UEU4.1
#=GS A0A1G4K3D0_9SACH/38-141   AC A0A1G4K3D0.1
#=GS PEX22_YEAST/50-167        AC P39718.1
#=GS G9A0A3_TORDC/38-136       AC G9A0A3.1
#=GS G8B7H4_CANPC/60-168       AC G8B7H4.1
#=GS G0W5E6_NAUDC/70-178       AC G0W5E6.1
#=GS A5DL35_PICGU/38-160       AC A5DL35.2
#=GS A0A1E4RDU0_9ASCO/70-208   AC A0A1E4RDU0.1
#=GS J5PA84_SACK1/50-167       AC J5PA84.1
#=GS A0A2H1A7U9_CANAR/37-155   AC A0A2H1A7U9.1
#=GS G8YPF8_PICSO/55-176       AC G8YPF8.1
#=GS A0A367XNR8_9ASCO/53-162   AC A0A367XNR8.1
#=GS PEX22_KLULA/50-155        AC Q6CLU6.1
#=GS A0A1G4MCC8_LACFM/36-140   AC A0A1G4MCC8.1
#=GS A0A1A0HIJ7_9ASCO/48-169   AC A0A1A0HIJ7.1
#=GS A0A2P7YVC1_9ASCO/36-154   AC A0A2P7YVC1.1
#=GS A0A4P9Z8Y6_9ASCO/43-166   AC A0A4P9Z8Y6.1
#=GS A0A1E3PI78_9ASCO/52-161   AC A0A1E3PI78.1
#=GS A0A1X7R4Y5_9SACH/42-152   AC A0A1X7R4Y5.1
#=GS I2GVS9_TETBL/40-141       AC I2GVS9.1
#=GS A0A2T0FL08_9ASCO/37-133   AC A0A2T0FL08.1
#=GS A0A4P6XH34_9ASCO/45-164   AC A0A4P6XH34.1
#=GS A7TPQ1_VANPO/60-161       AC A7TPQ1.1
#=GS J7RYN7_KAZNA/42-155       AC J7RYN7.1
#=GS A0A1E3P886_WICAA/40-147   AC A0A1E3P886.1
#=GS A0A7H9B3Y2_ZYGMR/43-148   AC A0A7H9B3Y2.1
#=GS A0A4C2E6W1_9SACH/47-153   AC A0A4C2E6W1.1
#=GS J8QB60_SACAR/50-166       AC J8QB60.1
#=GS PEX22_CANGA/58-160        AC Q6FP25.1
#=GS M3JEW5_CANMX/55-164       AC M3JEW5.1
#=GS A0A8H6F0V1_CANAX/29-158   AC A0A8H6F0V1.1
#=GS A0A5E8BUG0_9ASCO/50-185   AC A0A5E8BUG0.1
#=GS G0VJL8_NAUCC/72-181       AC G0VJL8.1
#=GS A0A1L0G8I7_9ASCO/45-167   AC A0A1L0G8I7.1
#=GS A0A1E3QK39_9ASCO/49-166   AC A0A1E3QK39.1
#=GS Q59KM6_CANAL/62-191       AC Q59KM6.1
#=GS A0A421J6J7_9ASCO/38-160   AC A0A421J6J7.1
#=GS PEX22_ASHGO/39-143        AC Q758W8.1
#=GS A0A512U6E9_9ASCO/46-168   AC A0A512U6E9.1
#=GS A0A0C7NGN2_9SACH/42-142   AC A0A0C7NGN2.1
#=GS A0A1E3NGV8_9ASCO/72-196   AC A0A1E3NGV8.1
A0A1S7H7X3_9SACH/43-148              .......rqg---EEKNSKKTSKTIVVTNTISC.qKE..........ISWGDLL.--EKDVVLLVPPG.VSFLEN....--PQDELSLH.............................YKIIRCNKMAGLWSCVRHLR............KDQLLYVA..GEIAED.....-.IPE.DIPRYVKRVT-a................
A0A1E4S0X4_CYBJN/43-151              ........dn--DSRRKYTQRPITIILTESILS..SN..........LPLNEIL.KKTSDVVLVVPPD.LSVDED....LQDEFEPDVE.............................YKVIECETYEGVWSVVKHLN............GEIIFVVK..DDLPSE.....-.LPD.GLERYVGEIVE.................
PEX22_DEBHA/56-178                   ........kl--RIAKRYTKKSIALTLSHSVLS..SQ..........LPLNEIL.LNSENVTFILPPN.LSMDDL....-VCNIGNADEverynl................pktllnnYKLLHCSNIDGYFNILKNLK............PDTLLVCS..EDLGIA.....NnVPR.DLHRFVKEIIN.................
A5DX24_LODEL/91-216                  ........vy--TISKKFLNKSIAITLSSSFLS..SQ..........LPLVDLI.TSNEKLIYIIPPN.LNEEDVgllnTAGNIVLQNKqelq.....................lppnFKILKCSNIQGYLQILKNLK............PDCLLLCS..DDLGISn..fnGvVLR.DLSNFIKNIIN.................
C4R500_KOMPG/42-169                  .........i-NQERKSYTRQKVAIIVSESILA..IQ..........LPIQEIL.KNTKDVVFVLAPT.IAKDEF...lRENEVDSGLS.............................FKVIETGTAIGCFHVLKHIKatynifnlhdflPSSTKTSS..DNEQLTfd.leEyVNL.HLNNFLQNVVE.................
A0A8H7GVJ0_9ASCO/45-164              .......kga---KKQHYRTKLVALTLLHSVLS..LG..........LPLDEIL.LSSGNVTFILPPY.LSVDDL....-AGQIASENAvyelp..................qtliqnYKLLQCLNMDGYFHLLKNLR............PDTLFVCA..DDLGIG.....R.APP.DLRRFVKEIV-t................
A0A1E4SMA5_9ASCO/39-154              .......syk---LSKQSVNKSIVLTLSSSVIN..SK..........LPLNDIL.VNSQNVVFILPPN.LSEEDLnnelNTEFVNRDNN.............................YKLLKCLNLQGYVQMLKNLQ............PDLLLICA..DDLGLSt...mK.LTQ.DLSRFIKQIVN.................
A0A448YFZ5_BRENA/59-183              ........id--RKKKQAKNTKITLIVSHKVIEliQKyntd..hedgIDLQEYL.RYYPNLTLILYPG.ISKDDI...rTFFEIDDRLS.............................YRIIPTTKEESVFHVAKQIN............SALNLFDF..GDFSTSs...eE.---.-----------iigqfhidsflrglid.
Q6C2P3_YARLI/51-160                  .........t-KSPKSTATNSKITVVVSQELVQ.sQL..........VDFKHLM.SVHPNLVVIVPPM.VANKFHr..aLKSSVGHDHG.............................VKVIRCDTDVGVIHVIKHIR............PDLAL-IA..DGVGDN.....-.IQG.EIKRFVG----sse..............
K0KTQ5_WICCF/53-159                  .........t-KEIANKYTSKPVTIVVTDSIIS..AK..........LRLGEIL.SLTQDVVLVLDPN.LNKQDL....--IGIEPQQE.............................YKIIECESYDGLWSIVKHLN............SELIFVVK..DDLIED.....-.LPK.NLSRFVGEIIE.................
G3B2E7_CANTC/39-159                  ........nl--QDPKKYTKKSIALTLSHSILS..SQ..........LPLDEIL.LNSENVTFILPPN.LSVDDL....EGNFAGGEAGsslpr...................allknYKLLNCSNFQGYFDIIKNLK............PDMLLVCS..DDLGIR.....SsLPS.DLSRFAKEIVE.................
A0A1E4SUI1_9ASCO/42-155              sqsqstktki-------PLNRSISLVITPNILKslTD..........DDLIDLL.ENYSNLTIIFHPS.ILDIPN....----VPRSYK.............................YRLIQTLKEESIFHVLKQIN............STMNLIPF..KQLSMSs...kE.IENfHLDRFL-----sglid............
A0A8H7USX0_9FUNG/132-237             ssdvntpnha--------------------FHE..NT..........VPLLNRL.AQIHDIYVIIHMN.SDKERH....-QITQLLNNNpnl......................lldsRKILHCSSEQGKLHLIRHLK............PHIHVEGG..TESD--.....-.---.-----------dgsfiinqldnveqkiw
A0A642V024_DIURU/52-170              .......gkl----KRQYTNKSIALTLSHSILN..SQ..........LPLSEIL.HNSENVTFILPPN.LDEDDV....-NYNIQKSTAtlpe....................evrnnYKLLKCQNIQGYFTVLKNLK............PDMLLMCQ..DDLGLSt...hS.IPK.DLNRFIKQIV-f................
G3AL82_SPAPN/52-160                  ......syii----SPKYSNKSIAITLSSTFIS..SK..........IPLNEIL.INSENMIFIIPPN.LNEEDL....---NVTIPPN.............................FKLLKCSNVDGYLQVLKNLK............PDLLFLCS..DDLGINi...sN.LSS.DMKLFIKTIVN.................
A0A421JUW2_9ASCO/56-164              ........ky--VISPKYSNKSIVITLSSTFIS..SK..........IPLNEIL.LNSENMIFIIPPN.LNEEDL....---NVNIPPN.............................YKLLKCSNVDGYLQVLKNLK............PDLLFLCS..DDLGIN....lKnLSS.DLKLFIKTIVN.................
H2ASY6_KAZAF/54-162                  .........e-EHRKEREKEPSRCVIVTKTLSE.mKD..........FDWQKFL.--KDDIVFIVVPG.ETFLDP...sQGFEIDPKVG.............................YKIIRCDTILGVWSCVKSLK............KDSLIVIG..DEVEGG.....-.IPD.DISNFTKNIR-d................
A0A1G4IQA8_9SACH/39-139              ......tqdg-----NSGKNQSICLILSEGLWS..KG..........VDWNRLS.--ERDAVVILTPD.FKEAPA....----QDLFPK.............................HRVIRCSTHEGVWYVVRHLR............KDVVIVEK..QQIEQ-.....-.IPS.DIYKFSRPI--en...............
G8BWQ5_TETPH/49-156                  .........t-NEKKTMMQKHSSIIILSTSLLK.dTS..........IDWNSIL.--ENDCVILVMPG.LKFDNL....--ANINKSYK.............................YKIIHCDTMTGIWSCIKHLR............LNTLYYIK..EELGPDy...dD.ISV.DLRNI------fttir............
A3LVY4_PICST/56-171                  .......egs---VAKKYGNKSIALTLSHSILN..SK..........LPLNEIL.INNENMIFILPPN.LSEDDV....-TYNLDPSKSgi........................mpnFKLLKCSNIQGYVQVLKNLK............PDMLLICS..DDLGLSf...mN.LSK.DLNNFIKTIVN.................
A0A1V2L9Y6_CYBFA/42-135              ........ss--TTDEKYTRKHITIILTDSIIS..SK..........LPINEIL.TKTTDVVLVIPPE.LTVDDL....-NEPLDPTIA.............................YKAIECKGIERYVGEIIELD............QNVSVIN-..------.....-.---.-----------esilssv..........
W1QAA3_OGAPD/42-152                  .........k-TSEASKSNGQSVSLVLTQKDLDsfSA..........AYLNEY-.---PNLTVILHPS.VDKSEF....LSRFNVQGNS.............................HKVIQVRSEESIFHVLKQLS............SKINLITM..NNLEMSa...nE.VEAfHLDKFLINVH-e................
A0A7H9HZ38_9SACH/36-134              ......ssdg----SKRERRGSRCVIVTKSVAE.fDE..........INWESLL.--KEDVVLVVAPG.VLFSHQ....---------S.............................YKVICCNTMSGLWSCVRHLK............KEQLLLKP..DDLETP.....-.MPA.DVPRYVGQVIH.................
C4Y073_CLAL4/43-162                  .........v-KKIKSKYANKSVTLTLSHSVLN..SD..........SSLEEIL.LNSNNVTFILPPY.LSVDDL....-QCNISGKRSmvvpe...................ilqdnYKLLKCSNMQGYFQLLKNLR............PDILIVCT..DDLGIT.....EqIPK.DLGRFVGKVV-t................
A0A4T0X754_9ASCO/56-175              .......plr----RKQERNTPITLVVSKSILDwiKNynqd..hedgIDLQNYL.ELYPNLVIILYPE.ITLSDI...eVYFEFNESYK.............................HRLLFTEKESSVFHMMKHLN............NNINLINL..NDFSMN.....-.-NE.EIDR-------iyrisqslh........
A0A2V1ASA9_9ASCO/35-154              ......eqti---SASKFTNKSIALTLSHSVLS..SD..........LPLEEII.MNSQNVTFILPPH.LSVDDL....-AGNIDTSQTglsq....................tllnnYKLLRCSNIDGYFHMLKNLK............PDTLIVCA..DDLGIH.....DkMPK.DLPRFVKEVV-t................
A0A367YMM0_9ASCO/53-162              ........sy--TVSKRYSNKSIAITLSSSFLS..SS..........LPLNKIL.TNSERMIFIIPPN.LTEDDL....NLSYI--PPN.............................FKLLKCSNLQGYLQILKNLK............PDLLLMCS..DDLGLDf...tQ.IKK.DLNMFINDIIN.................
I6NCM2_ERECY/37-142                  ......tpek---KRNYKEYRRKCIIWSPAVE-..QS..........SNLETIL.--LEDSVILIPPE.SGSLQD....-LLAVGNENA.............................YKIIKCDTWQGVWSCVRHLR............AHYLLLKE..CEIPEA.....-.IPV.DILNYVNKII-s................
C5M7G2_CANTT/51-160                  ........sy--TISKRYSDKSIAITLSSSFLS..SS..........LPLNKIL.TSSEKMIFIIPPN.LTEDDL....NLSYI--PPN.............................FKLLKCSNLQGYLQILKNLK............PDLLLMCS..DDLGIDf...tQ.IKK.DLNMFINDIIN.................
A0A8J5UEU4_9ASCO/31-139              .......kyl---ISKQYSNKSIAITLSSTFLS..SN..........IPLNEIL.INSENMIFIIPPN.LSEKDL....---DINIPPN.............................FKLLKCSNVQGYLQMLKNLK............PDLLFLCS..DDLGINf...mN.LNK.DLRMFIKTIIN.................
A0A1G4K3D0_9SACH/38-141              ....etdtdq------LKSSAHRVILVTETVFK..DY..........EKWRGEL.--QNGCVLVIPPN.RDYDSV....-LKLENPKYE.............................SQIIKCDSMTGVWAVVRHLR............KPLTL-AS..EDLDM-.....-.IPD.ELSRFVGEIIE.................
PEX22_YEAST/50-167                   ........ds--VKENKKARKSKCIIMSKSIQG..LP..........IKWEEYA.--ADEVVLLVPTS.HTDGSMkqaiGDAFRKTKNE.............................HKIIYCDSMDGLWSCVRRLG............KFQCILNS..RDFTSSggsdaAvVPE.DIGRFVKFVVD.................
G9A0A3_TORDC/38-136                  ........vs--DNKDSSKRKSRCVVITDSVAA.sKE..........FNWDDFL.--TRDIVLLVAPG.IHFSQE....---------S.............................FKVIHCDTMVGLWSCVRHLK............KDQLLLEQ..SEINES.....-.IPV.DIPRYTKEIL-n................
G8B7H4_CANPC/60-168                  ........sf--TISKKYLNKSIAITLSSSFLS..SQ..........LPLNDIL.TTQENMIFIIPPN.LNEDDL....---NLKIPPN.............................FKLLKCSNVQGYLQILKNLK............PDCLLLCS..DDLGINy...sN.LSS.DLRNFIRTIIN.................
G0W5E6_NAUDC/70-178                  ........nt--VIDTDNKKPSKCIIVTEQINN.iTN..........VNWEKLL.--KKDVVLLLSPD.ISKIHE...lNEDNVEKANL.............................SKVIHCETGLGMWACVKSLR............KDQLICMP..SDLEDG.....-.IPD.DIKHFVKQII-a................
A5DL35_PICGU/38-160                  .......sei---SRKKYTNKSVALTLSHSVLN..SQ..........LPLNDIL.MNSENVTFILPPN.LSLDDL....-ACNISDENDgsatkl................prtliqnYKLLNCKNIQGYFNLLKNLK............PDTLLVCS..DDLGIT.....SaVPR.DINRFVKEIIN.................
A0A1E4RDU0_9ASCO/70-208              ........kl--KTHDKYTSKSIALTLSHSVLN..SS..........LPLNDIL.LNSENITFILPPN.LSLDDL....-ACNIKIVNEpdntntnstttttanatinyklpqtliknYKLLNCNNIQGYFNIIKNLK............PDMLLVCA..DDLGIK.....SdIPK.DLKRFAKEII-t................
J5PA84_SACK1/50-167                  ........gs--ATKNKKARKSKCVIMSKSLQG..LS..........IDWSEYV.--TEDVVLLVPMS.QTEGSVreaiKQAFYSSGNE.............................HKIILCDNMDGLWSCVRRLG............KFQCILNS..KDFSGAdgsdtAvVPE.DIGRFVNFVVD.................
A0A2H1A7U9_CANAR/37-155              .......qti---SATKYTNKSIALTLSHSVLS..SD..........LPLDEII.MNSQNVTFILPPH.LSVDDL....-AGNIDTSQSglsq....................tllnnYKLLRCSNIEGYFHMLKNLK............PDTLIVCA..DDLGIQ.....DkMPK.DLPRFVKEVV-t................
G8YPF8_PICSO/55-176                  ........kl--KDRKNYTKKSVALTLTHSVLS..SK..........LPLTDII.LNSENVTFILPPS.LSLEDL....-EAIIDKDESgealit.................sslmqnYKVLKSNNIQGYYSLIKSLR............PDTLLVCA..DDMGID.....DhLPK.EMNRFIKQIV-t................
A0A367XNR8_9ASCO/53-162              ........sy--TVSKRYSNKSIAITLSSSFLS..SS..........LPLNKIL.TNSERMIFIIPPN.LTEDDL....NLSYI--PPN.............................FKLLKCSNLQGYLQILKNLK............PDLLLMCS..DDLGLDf...tQ.IKK.DLNMFINDIIN.................
PEX22_KLULA/50-155                   .......rnp---NIRDVKPKSKCYVLTQDLFD..KI..........ENWQEEL.--SKDSVMLVLPE.VAHLGN....HLKLQLSSIE.............................HKIVIFNNSSAVWSAVRHLK............KYELVISR..DKTSD-.....-.MPV.DLRRYVGQIS-h................
A0A1G4MCC8_LACFM/36-140              ........ps--KEKKSEKKDPKTIIVTNTVYR..AV..........DNWESIL.--QDDVVLLIPPN.CGFKDD....-LQSLDRDNS.............................HKIIGCDTMEGLWSVTRHLR............KKELVLLP..GELDG-.....-.IPD.DLARYCERIV-r................
A0A1A0HIJ7_9ASCO/48-169              ........al--SRRRQYRNKSITVTLLHSVLN..LG..........LPLNEML.LSSENVTFILPPY.LSVDDL....-ACQIESSENgalyel................pltlirnYKLLKCSNIDGYFHLLKDLR............PDVLFVCT..DDLGID.....R.VPP.DLRRFVSEIV-a................
A0A2P7YVC1_9ASCO/36-154              .......qti---SASKYTNKSIALTLLHSVLS..SD..........LPLEEII.MNLQNVTFILPPH.LLVDDL....-AGNIDTLQSglsq....................tllnnYKLLRCLNLDGYFHMLKNLK............PDTLIVCA..DDLGIH.....DkMPR.DLPRFVPEVV-t................
A0A4P9Z8Y6_9ASCO/43-166              ......fkga-----QANSKKSIAVTLLHSVLR..SD..........LPLNDIL.LTSENVTFILPPC.LSVDDLl..gQIQGFDGDEKrtymlp.................qtliknYKLLKCSNMKGYFHLLKNLK............PDLLYVCS..DDLGIT.....KlVPQ.DMHRFVKEVV-t................
A0A1E3PI78_9ASCO/52-161              .......sks--SNKHINENKMIAITVSLNLLL..SG..........IPLMLLL.SRYPNIVVVLTKE.VSIDNT...pLASQIPRGME.............................HKIIPCETTIGIIHILKHLK............PQYVVLAA..DTASY-.....-.VER.DIKGFVGQIT-s................
A0A1X7R4Y5_9SACH/42-152              ........dk--TSKTVHKYKSRCIIMTKSISE.sQD..........IKWATIM.-KDPNVVVIVAPK.VEFPQLv..yPNQVIDNNDL.............................FKIIHCDTNNGVWACVKSLK............KDELLLVS..HDLEHE.....-.IPT.DIIRYVKHIN-d................
I2GVS9_TETBL/40-141                  ....nktskk----IEYDTKYSKCFVVTKSIKD..-K..........YNWNRVL.--QGNSVAILAPN.IEIGTI....-----DENLK.............................HKIVVCSLEDSIWPVIKHLK............KDCLIIST..DDFKE-.....-.IPN.DIPRFVKIIL-d................
A0A2T0FL08_9ASCO/37-133              ....deipav------KKLGDSVCVVVSES---..--..........KDYSKLL.QAYPRLVIVGAQS.IALKSG....------TADD.............................YRLIETETAEGWIHVVKHLR............PEKLV-VE..DELSPE.....-.LPA.GIERFVKKIL-t................
A0A4P6XH34_9ASCO/45-164              .......kga---RKQHYRTKLVALTLLHSVLS..LG..........LPLDEIL.LSSGNVTFILPPY.LSVDDL....-AGQIASENAvyelp..................qtliqnYRLLQCLNMDGYFHLLKNLR............PDTLFVCA..DDLGIG.....R.APP.DLRRFVKEIV-t................
A7TPQ1_VANPO/60-161                  ......gngg---------QDSKTIILTKSLCE.nKG..........IDWKRLF.--DTNCVVLVTPG.LKFQPS....-KDSVNSTND.............................YKIIHCDTMEGLFSCAKHLG............KKKLLYVP..DELESG.....-.LPV.DISRFVREVVE.................
J7RYN7_KAZNA/42-155                  ........eq--RLSREEAAESKCVVVTPSVCDvqNM..........VHWEMLInSDQEDIVFLVAPG.CHDRFSs..eVLSLVDEQFK.............................YKAINCETVDGIWYCVKSLM............KQQLYVIP..SEVSNG.....-.IPN.DIARYVQDI--gq...............
A0A1E3P886_WICAA/40-147              .........q-EQITTKYTSKPITIILTDSIIS..SN..........LPINEIL.LKTDNIVLVIPPN.LSVDDL....-NEEIDESIS.............................FKIIECSTNDGVWSVVKHLN............SEVIFVVN..DDLNYE.....-.IPK.NLQRYVGEIIE.................
A0A7H9B3Y2_ZYGMR/43-148              .......kte---NERLSSFTSQCILMTPSISK.lKT..........MDWSSVL.--KYDVVLLVPPE.VEFLAD....--TDLASNNN.............................YKVLYCDTMSGLWSCIRHLR............KHQLIYVS..EDLQDT.....-.MPQ.DIPRYVKSIID.................
A0A4C2E6W1_9SACH/47-153              ......gksv-----QKTRGSSRAIIVTKSIAQ.eEG..........IDWINLL.--QEDVVLLVLPG.ISFFEG....SAQEELSAHR.............................YKIIRCDTMVGLWSCVKHLQ............KEQLLYIE..DEITDG.....-.LPN.DIGRYIKKLVN.................
J8QB60_SACAR/50-166                  ....nsisqp------RKSRGSKCIIMSKSVQG..LS..........IDWGRYA.--NDEVVLLVPMS.QTNGSFkqtiKDAFCSTGNE.............................HKIIYCDSTDGLWSCVRRLR............KLQCVLNS..KDFAGSss.gtAvVPE.DIGRFVNFVID.................
PEX22_CANGA/58-160                   ......iklg-----KKRLHRSLCVIISNKLSN.lVE..........LDWDEIL.--QEDIVFLILPS.VNDFQN....--SNDIKTDT.............................HKIINCDTELGLWACVRTLK............KNELLVCA..DDIK--.....-.VPD.DIGRYCDKIS-q................
M3JEW5_CANMX/55-164                  ........ty--TVSKKYSNKSIAITLSSSFLS..SK..........LPLNKIL.INSENMIFIIPPN.LTESDL....NLSYI--PPN.............................FKLLNCSNLQGYLQILKNLK............PDLLLMCS..DDLGINf...gQ.IKK.DLNMFIRDIIN.................
A0A8H6F0V1_CANAX/29-158              ........kf--RISKRYSNKSIAITLSSTFLS..SN..........LPLNEIL.INSENMIFIIPPN.LNEDDLp.iiETKDTDTDNAntntnts...............fykdqsnFKLLKCSNFQGYLQILKNLK............PDLLLLCS..DDLGINf...kK.LQS.DLLNNLK----ldfin............
A0A5E8BUG0_9ASCO/50-185              ........is--EPKKKTSTQQVAIILSKDLIE.nGD..........VPFADLL.AKFPNLVFIYFPAdFSEEGE....EEEEN----Edlprdieqlqlp....dpiaevidiakdsYKFLPCGTATGATHIVKHLR............PQVLVVPRshNDREDR.....QvKEQ.DVTRFVGSVQ-e................
G0VJL8_NAUCC/72-181                  ........ss--VKETKKKQPSKCVIISNKISN.vEG..........MDWSELL.--DEDITLIVAPG.VTFLDQp..kEEESIGREHQ.............................FKVIRCDTLIGMWACVKSLR............KDQLIVCP..GDIEDG.....-.IPE.GIDQFVKKIIK.................
A0A1L0G8I7_9ASCO/45-167              ........gk---RRTNYTNKSIALTLLHTILN..SD..........LPLNEIL.MNSENVTFILPPY.LSVDDL....-ACNIHGADGdasvyal...............prtliknYKLLKCLNIQGYFHVLKNLK............PDMLFVCS..DDLGIT....lK.VPP.DLGRFVKEII-t................
A0A1E3QK39_9ASCO/49-166              .......plt----EKRYTTKAITVVLTSSIIA..AR..........LPLEELL.HHSNNIVFVLPPK.LRKAELf..aDQRLMSRK-Gvng......................vihkYKIIECDNARGMWFVVKHLK............PDTLIVCE..DDLPLH....cE.MPQ.EINNFVRDVV-i................
Q59KM6_CANAL/62-191                  ........kf--RISKRYSNKSIAITLSSTFLS..SN..........LPLNEIL.INSENMIFIIPPN.LNEDDLp.iiETKDTDTDNAntntnts...............fykdqsnFKLLKCSNFQGYLQILKNLK............PDLLLLCS..DDLGINf...kK.LQS.DLLNNLK----ldfin............
A0A421J6J7_9ASCO/38-160              .......sei---SRKKYTNKSVALTLSHSVLN..SH..........LPLNDIL.MNSENVTFILPPN.LSLDDL....-ACNIGDENDgsatkl................prtliqnYKLLNCKNIQGYFNLLKNLK............PDTLLVCS..DDLGIT.....SaVPR.DINRFVKEIIN.................
PEX22_ASHGO/39-143                   ........ie--VEKKLRRSVSRCVVVTQGIQN..ED..........MI-HDLL.--FEDTVMLLAPG.CTAEGR....-LKSASRENA.............................YKVISCTTWQSVWACVRHFR............KHTLLVRT..SEVPSG.....-.VPA.DIGGYVSDIS-d................
A0A512U6E9_9ASCO/46-168              .......ala---KRAHYTSKSIALTLSHSVLS..SG..........LPLNDIL.LSSANVTFILPPY.LSVEDL...aGQIECDE--Dsrlyel................pqtlmenYKLLRCSNMDGYFHLLKNLK............PDMLFVCA..DDLGIR.....DrAPP.DLRRFVKEII-t................
A0A0C7NGN2_9SACH/42-142              .......tid----ETEQNSISACIVFTEDMYE..SG..........LDWEGLI.--SMQAVVILPPK.ITLRST....----VVQFPV.............................SQIIECGTEDGVWSVVRHLR............KDIVVVSP..LSLNS-.....-.VPA.DIYRFSEPV--te...............
A0A1E3NGV8_9ASCO/72-196              .....nrlrp-----KQRTDVSISLVVSKSVLR..QMeqyntehedgVDLQNYL.RLYPRMVVVLYPG.LTPADV...eCYFELDDDVR.............................HRVLETGKEESVFHVLKQVG............SDITLLCF..DDFAID....rA.---.-----------tidkrfrldnvlrnvvs
#=GC seq_cons                        ........th....ppchss+SlslslocSlls..sp..........lsls-lL..tscsllhIlPPs.lshc-l......tplsps.s.............................aKllcCsshpGhapllKpL+............sDhLllss..DDLuhs.......lPp.DlpRFlppIl..................
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