#=GF ID Phage_tail_NK
#=GF AC PF16532.9
#=GF DE Sf6-type phage tail needle knob or tip of some Caudovirales
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE pdb_3rwn
#=GF GA 27.00 27.00;
#=GF TC 28.50 38.40;
#=GF NC 26.90 23.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0100
#=GF RN [1]
#=GF RM 21705802
#=GF RT Atomic structure of bacteriophage Sf6 tail needle knob.
#=GF RA Bhardwaj A, Molineux IJ, Casjens SR, Cingolani G;
#=GF RL J Biol Chem. 2011;286:30867-30877.
#=GF RN [2]
#=GF RM 23951045
#=GF RT The tip of the tail needle affects the rate of DNA delivery by
#=GF RT bacteriophage P22.
#=GF RA Leavitt JC, Gogokhia L, Gilcrease EB, Bhardwaj A, Cingolani G,
#=GF RA Casjens SR;
#=GF RL PLoS One. 2013;8:e70936.
#=GF DR INTERPRO; IPR032395;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Phage_tail_NK is the globular tip protein of some tailed
#=GF CC bacteriophages. Tailed bacteriophage virions deliver DNA to
#=GF CC susceptible cells after adsorbing to specific receptors on the
#=GF CC surface of the bacteria. In the Gram-negative bacteria these
#=GF CC receptors are surface proteins or polysaccharides. In the phage
#=GF CC Sf6-type needle, this distal tip folds into a knob with a
#=GF CC TNF-like fold, similar to the fibre knobs of bacteriophage PRD1
#=GF CC and Adenovirus. It contains three bound L-glutamate molecules
#=GF CC that are bind tightly in the crevices between the trimers of
#=GF CC this trimeric tip [1,2].
#=GF SQ 34
#=GS Q56EK0_9CAUD/104-288 AC Q56EK0.1
#=GS A0A6G6XU03_9CAUD/11-163 AC A0A6G6XU03.1
#=GS A0A6B9X1T4_9CAUD/79-256 AC A0A6B9X1T4.1
#=GS A0A4P2WVF2_9CAUD/11-163 AC A0A4P2WVF2.1
#=GS A0A219YAS4_9CAUD/104-288 AC A0A219YAS4.1
#=GS A0A2Z3DUY0_9CAUD/11-162 AC A0A2Z3DUY0.1
#=GS A0A248H7K0_9CAUD/11-163 AC A0A248H7K0.1
#=GS A0A0B6VR09_9CAUD/95-253 AC A0A0B6VR09.1
#=GS A0A5Q2U799_9CAUD/76-243 AC A0A5Q2U799.1
#=GS Q716G6_BPSFV/108-282 AC Q716G6.1
#=GS A0A1P8L658_9CAUD/24-197 AC A0A1P8L658.1
#=GS A0A7S9XCG3_9CAUD/1-68 AC A0A7S9XCG3.1
#=GS I0J343_9CAUD/11-163 AC I0J343.1
#=GS Q56BS0_9CAUD/70-229 AC Q56BS0.1
#=GS A0A7S6HSC5_9CAUD/148-302 AC A0A7S6HSC5.1
#=GS A0A7L7STQ1_9CAUD/108-282 AC A0A7L7STQ1.1
#=GS A0A7U3VC23_9CAUD/136-317 AC A0A7U3VC23.1
#=GS A0A0F6N5P8_9CAUD/24-197 AC A0A0F6N5P8.1
#=GS A0A0N7CFE0_9CAUD/1-42 AC A0A0N7CFE0.1
#=GS A0A5B9N8A5_9CAUD/7-187 AC A0A5B9N8A5.1
#=GS A0A5B9N4W5_9CAUD/107-280 AC A0A5B9N4W5.1
#=GS A0A240F401_9CAUD/114-288 AC A0A240F401.1
#=GS A0A3G3BY92_9CAUD/18-162 AC A0A3G3BY92.1
#=GS A0A219YDD3_9CAUD/116-288 AC A0A219YDD3.1
#=GS A0A6M3TCL2_9CAUD/24-197 AC A0A6M3TCL2.1
#=GS A0A482N0D7_9CAUD/11-163 AC A0A482N0D7.1
#=GS A0A514A0G4_9CAUD/7-187 AC A0A514A0G4.1
#=GS A0A0H2VSP9_SHIFL/108-282 AC A0A0H2VSP9.1
#=GS E1XTI9_BPSAV/11-163 AC E1XTI9.1
#=GS A0A3G3M6P6_9CAUD/108-282 AC A0A3G3M6P6.1
#=GS A0A077K9Y9_9CAUD/1-127 AC A0A077K9Y9.1
#=GS A0A0B6VT00_9CAUD/95-253 AC A0A0B6VT00.1
#=GS A0A410T4K3_9CAUD/90-248 AC A0A410T4K3.1
#=GS A0A2S1PG26_9CAUD/1-68 AC A0A2S1PG26.1
Q56EK0_9CAUD/104-288 aastiasvdltpvriaatdsngkmttslvsvs-----------.......-------------DL.....DLIK...DRTTRVKSELEWTGLNIDVTG.T.AL..NLVGAL..KAITP..VYG..S.WAPMFDIINDKMVA.AkNDDRTLLYKIAITGTF..D.NT.SSTNALTLT.TTiGSN.IDVSSAVRLPNQ.N.P.QNIN.YISLISVDKNGNFATNGASLTLRSTTSDFTITRVRLIAEQ
A0A6G6XU03_9CAUD/11-163 ............................nmlq-----------.......---------------.....----...--THRIKVEVRFSGLTAALPA.G.ATgvDLLTLLdgKTPHP..SSV..TgLAPFFKLSDHKFHA.F.PVDSILPVKVNIIGTW..S.GS.TTNRTMLLD.FV.GST.GNQISKSRDSSV.P.PpDVLS.FITFFSVDKAGNLATNGAQMKLYSYGGDFTINEIVLIAEQ
A0A6B9X1T4_9CAUD/79-256 ............................aenr----LTLLEDD.......VDYLLDKVIDLETRI.....EDLEdwrVYMTRQKSEVVYSGISLNIPT.T.PS..NLLTLL..AALTP..TSG..S.LAPFFNTATGRLVA.L.NKNKDLKLKISVVGAF..A.GG.TTNRSMEIT.FG.TVV.PDTLVVSRNPAT.P.T.DNLL.FNTFFSVEEGDDITSPGINMTIQSNGSAFTATQIKLIATQ
A0A4P2WVF2_9CAUD/11-163 ............................nmlq-----------.......---------------.....----...--THRIKVEVRFSGLTAALPA.G.ATgvDLLTLLdgKTPHP..SSV..TgLAPFFKLSDHKFHA.F.PVDSILPVKVNIIGTW..S.GS.TSNRTMLLD.FV.GST.GNQLSKSRDSSL.P.PpDVLS.FITFFSVDKAGNLATNGAQMKLNSYGGDFTINEIILIAEQ
A0A219YAS4_9CAUD/104-288 aastiasvdltpvriaatdsngkmttslvsvs-----------.......-------------DL.....DLIK...DRTTRVKSELEWTGLNIDVTG.T.AL..NLVGAL..KAITP..VYG..S.WAPMFDIINDKMVA.AkNDDRTLLYKIAITGTF..D.NT.SSTNALTLT.TTiGSN.IDVSSAVRLPNQ.N.P.QNIN.YISLISVDKNGNFATNGASLTLRSTTSDFTITRVRLIAEQ
A0A2Z3DUY0_9CAUD/11-162 ............................nmlq-----------.......---------------.....----...--THRIKTEVRFSGLSLNIPT.G.ATgvDLLSLF..VDKTP..VAGstA.MTPFFDLATNKFKV.F.NNDSTVTLKINLIGAW..Q.GS.TNNRTLELN.FV.GSA.GNQLTKSRDAAL.T.G.QDILsFPTFFSVDKDGNLATNGSQIIARSYGNDFTITEAIFIAEQ
A0A248H7K0_9CAUD/11-163 ............................nmlq-----------.......---------------.....----...--THRIKVEVRFSGLTAALPA.G.ATgvDLLTLL..DGKTPhpASV..TgLAPFFKLSDHKFHA.F.PVDSILPVKVNIIGTW..S.GS.TSNRTMLLD.FV.GST.GNQLSKSRDSSL.P.PpDVLS.FITFFSVDKAGNLVTNGAQMKLNSYGGDFTINEIILIAEQ
A0A0B6VR09_9CAUD/95-253 ..................nlghtgteqdflns-----------.......---------------.....----...IAGTRQKSEAFWTGLSIALTA.G.TT.yNLINIL..KGTPT..TAG..Q.LAPFFRIADNKLWP.F.NSDTTMTFKLNVTGAF..T.GA.SQARSLTIN.FV.GTN.GNTLVQNRPEN-.A.I.DTMS.FATFFSVDKNGQMATNGSVIDIIANGGVFTINSVLLVAEQ
A0A5Q2U799_9CAUD/76-243 .......idlslfvtdsdltsalalkldankl-----------.......---------------.....----...--PIRQKTEVYYSSVSLAIPT.T.ET..NLITLL..KTLTP..TTG..T.LSKFFNTTSNKLNV.Y.DDNASVLFKLNLTGSW..A.SS.TENRSMSLN.FA.GTN.GNKLTINRISGI.T.P.DVLQ.FTTYFSIDKDGNIATNGTAPLIQSFGSVFTATSILITAEQ
Q716G6_BPSFV/108-282 ................................NESDISSLDTR.......VQSLESQVSDHETRI.....DALE...YATTRKKSEVVYSGVSVTIPT.A.PT..NLVSLL..KTLTP..SSG..T.LAPFFDTVNNKMVV.F.NENKTLFFKLSIVGTW..P.SG.TANRSMQLT.FS.GSV.PDTLVSSRNSAT.T.T.DNIL.LATFFSVDKDGFLATNGSTLTIQSNGASFTATTIKIIAEQ
A0A1P8L658_9CAUD/24-197 ........................anlqgdlv-----------.......----DSKLSDDGTKLtyngnEVTD...SRTQRKKTEVYYSGVSVTLTAgT.QY..NLVNLL..KALTA..NSG..T.LAPFFDTTSNKLKV.I.NDNATCMFKLNLVGNW..A.NA.SSDRSIQVD.FV.GTN.GNRLVANRSSAT.T.D.DSLT.LSTFLSVDKNGNLATNGSTVNLTSVGINFTITSALLIAEQ
A0A7S9XCG3_9CAUD/1-68 ................................-----------.......---------------.....----...---------------------.-.--..------..-----..---..-.--------------.-.----------------..-.--.-----MIVD.FV.GSV.GNQLSRSRDASVpP.P.DTLS.FITFFSVDKDGNLATNGAQIKLYSYGGDFTITEVVLIAEQ
I0J343_9CAUD/11-163 ............................nmlq-----------.......---------------.....----...--THRIKVEVRFSGLTAALPA.G.ATgvDLLTLL..DGKTPhpASV..TgLAPFFKLSDHKFHA.F.PVDSILPVKVNIIGTW..S.GS.TSNRTMLLD.FV.GST.GNQLSKSRDSSL.P.PpDVLS.FITFFSVDKAGNLVTNGAQMKLNSYGGDFTINEIILIAEQ
Q56BS0_9CAUD/70-229 ...................gnegktlddffds-----------.......---------------.....----...IAGVRKKSEVFWTGLSLVIPEdT.PT..NFINLI..KGTIP..TTG..T.LEPFFKITDNKLHP.F.NENSTLTFKLNLKGTF..TgAT.TAQRSVTLD.FV.GTQ.GNTLTLNRSQSV.T.T.STLS.FVTFFSVDKNGNMVTNGTAFNIFANGSPFTVSEVLLVAEQ
A0A7S6HSC5_9CAUD/148-302 ......................esqyivgphv-----------.......---------------.....----...--RIRKKTEVKATGTAFSMQS.SqSY..NVVDLL..ASLGI..DSG..E.LEPLFKQAGKVLKP.Y.NTESDVHFKIVLLGTW..S.GGgGGNRSMELN.VG.TAT.ENRFIQNRSDAV.T.S.DSFT.FNSMVAVDVGGPAATNGVAFNVKPNGGNFSLTTVSVIATQ
A0A7L7STQ1_9CAUD/108-282 ................................NESDIASLDTR.......VQSLESQVSDHETRI.....DALE...YATTRKKSEVVYSGVSVTIPT.A.PT..NLVSLL..KTLTP..SSG..T.LALFFDTVNNKMVV.F.NENKTLFFKLSIVGTW..P.SG.TANRSMQLT.FS.GSV.PDTLVSSRNAAT.T.T.DNIL.LATFFSVDKDGFLATNGSTLTIQSNGAAFTATTIKIIAEQ
A0A7U3VC23_9CAUD/136-317 ................................NTTDIDALDTRlttaegsISTLQSTVGDHSTRI.....SALE...YATTRKKSEVVYSGVSVTIPT.A.PT..NLVSLL..KTLTP..SSG..T.LAPFFDTVNNKMVV.F.NENKTLFFKLSIVGTW..P.SG.TANRSMQLT.FS.GSV.PDTLVSSRNSAT.T.T.DNIL.LATFFSVDKDGFLASNGSTLTIQSNGAAFTATTIKIIAEQ
A0A0F6N5P8_9CAUD/24-197 ......ansqgdlvdskltddgtklayngnev-----------.......---------------.....--TD...SRTQRKKTEVYYTGVSVTLTAgT.QY..NLVNLL..KALTA..NSG..T.LAPFFDTTSNKLKV.I.NDNASCMFKLNLVGNW..A.NA.SSDRSLQVD.FV.GTN.GNRLVANRSSAT.T.A.DSLT.LSTFLSVDKNGNLATNGSTVNLTAVGINFTITSALLIAEQ
A0A0N7CFE0_9CAUD/1-42 .............................msf-----------.......---------------.....----...---------------------.-.--..------..-----..---..-.--------------.-.----------------..-.--.---------.--.---.------------.-.-.----.-ITFFSVDKDGNLATNGAQMKLYSYGGDFTITEVVLIAEQ
A0A5B9N8A5_9CAUD/7-187 ...............nngdsmfdvrtlklnpt-----------.......----ITQVNQNTTNL.....STLI...TKTTRIKSEMNWVGVNIPLTNgT.VY..NLVTLL..KATPQ..TNG..T.FAPMFDTTANKMVAgV.NDDRTLFWKLVIEGSFsgP.IT.SNSGSLEVD.FT.GGI.VEKYINGRDNYS.A.P.DIFN.FTSLISVDKNGLFVTNGATVSLTALDRDFTITRVRLIAEQ
A0A5B9N4W5_9CAUD/107-280 .........................tltlqdh--------EGR.......ILAAEATLVDHENRI.....DAIE...YAITRKKSELVFTGLSLDIPT.T.SV..NLVTLL..KALTP..ASG..T.FAPFFDTTNDKMVV.F.NEDKTLNFKLVIAGSW..A.SG.SLNRSMSVT.FS.GTV.PDTLNEIRYPGT.T.T.DNCT.FPTFFSVDTGGFLATNGSTITIVSNGSAFTATTVKLIAEQ
A0A240F401_9CAUD/114-288 ..........tpvriaatdsngkmttslvsvs-----------.......-------------DL.....DLIK...DRTTRVKSELEWTGLNIDVTG.T.AL..NLVGAL..KAITP..VYG..S.WAPMFDIINDKMVA.AkNDDRTLLYKIAITGTF..D.NT.SSTNALTLT.TTiGSN.IDVSSAVRLPNQ.N.P.QNIN.YISLISVDKNGNFATNGASLTLRSTTSDFTITRVRLIAEQ
A0A3G3BY92_9CAUD/18-162 .............................gsg-----------.......---------------.....----...--SVRRKSECYFSGLNLVIPT.T.PT..NLISLI..KSL-P..HTG..S.LSPFFNTTTNKFNV.F.NNDSTVTFKVNVVGSW..A.GS.SSQRSMTVS.FP.STQ.GNTLVESRDQAV.T.A.DILS.FPTFFSVDAGGNLALNGSDITIQSNGAAFTASAILIIAEQ
A0A219YDD3_9CAUD/116-288 ............vriaatdsngkmttslvsvs-----------.......-------------DL.....DLIK...DRTTRVKSELSWSGLSLAITS.T.PS..NLITLL..KASPQ..TSG..A.WAPMFNTTTDKMVA.AkNDDRTLFYKIAITGTF..A.SA.SSANALTLTtTS.GAN.VDVSTAIRLANQ.V.S.QNVN.FGSFISVDKNGNFATNGATLNIESTTSDFTITSVRLIAEQ
A0A6M3TCL2_9CAUD/24-197 ......ansqgdlvdskltddgtkltyngnev-----------.......---------------.....--TD...SRTQRKKTEVYYTGVSVTLTAgT.QY..NLVNLL..KALTA..NSG..T.LAPFFDTTSNKLKV.I.NDNASCMFKLNLVGNW..A.NA.SSDRSIQVD.FV.GTN.GNRLVANRSSAT.T.A.DSLT.LSTFLSVDKNGNLATNGSTVNLTAVGINFTITSALLIAEQ
A0A482N0D7_9CAUD/11-163 ............................nmlq-----------.......---------------.....----...--THRIKVEVRFSGLTASLPA.G.STgvDLLTLL..DGKTPhpASV..TgLSPFFKLSDHKFHA.F.PVDSILPVKVNIIGSW..S.GS.TANRTMLLD.FV.GST.GNQLSKSRDSSV.PpP.DTLS.FITFFSVDKAGNLATNGAQMKLYSYGGDFTINEIVLIAEQ
A0A514A0G4_9CAUD/7-187 ...............nngdsmfdvrtlklnpt-----------.......----ITQVNQNTTNL.....GTLI...TKTTRIKSEMNWVGVNIPLTNgT.VY..NLVTLL..KATPQ..TNG..T.FAPMFDTTANKMVAgV.NDDRTLFWKLVIEGSFsgP.IT.SSSGSLEVD.FT.GGI.VEKYINGRDNYS.A.P.DIFN.FTSLISVDKNGLFVTNGATVSLTALDRDFTITRVRLIAEQ
A0A0H2VSP9_SHIFL/108-282 ................................NESDISSLDTR.......VQSLESQVSDHETRI.....DALE...YATTRKKSEVVYSGVSVTIPT.A.PT..NLVSLL..KTLTP..SSG..S.LAPFFDTVNNKMVV.F.NENKTLLFKLSIVGTW..P.SG.TANRSMQLT.FS.GSV.PDTLVSSRNAAT.T.T.DNIL.LATFFSVDKDGFLATNGSTLTIQSNGAAFTATTIKIIAEQ
E1XTI9_BPSAV/11-163 ............................nmlq-----------.......---------------.....----...--THRIKTEVRFSGLSQLLTS.G.ATgiDLLTVLdgKTPNP..SSP..TgLAPFFKLSDHKFHA.F.PYDSILPVKVNIVGSW..S.GS.TSNRTMIVD.FV.GSL.GNQLSRSRDASVpP.P.DTLS.FITFFSVDKDGNLATNGAQIKLYSYGGDFTITEVVLIAEQ
A0A3G3M6P6_9CAUD/108-282 ................................NESDIASLDTR.......VQSLESQVSDHETRI.....DALE...YATTRKKSEVVYSGVSVTIPT.A.PT..NLVSLL..KTLTP..SSG..T.LAPFFDTVNNKMVV.F.NENKTLFFKLSIVGTW..P.SG.TANRSMQLT.FS.GSV.PDTLVSSRNSAT.T.T.DNIL.LATFFSVDKDGFLATNGSTLTIQSNGASFTATTIKIIAEQ
A0A077K9Y9_9CAUD/1-127 ...............................m-----------.......---------------.....----...------------------IPT.T.PT..NLISLI..KSL-P..HSG..S.LSPFFNTTINKFKA.F.NNDSTVTFKVNVVGSW..A.GS.SSQRSMTVS.FP.STQ.GNTLVESRDQAV.T.A.DILS.FPTFFSVDAGGNLALNGSDITIQSNGAAFTASAILIIAEQ
A0A0B6VT00_9CAUD/95-253 ..................nlghtgteqdflns-----------.......---------------.....----...IAGTRQKSEAFWTGLSIALTA.G.TT.yNLINIL..KGTPT..TAG..Q.LAPFFRIADNKLWP.F.NSDTTMTFKLNVTGVF..T.GA.SQARSLTIN.FV.GTN.GNTLVQNRPEN-.A.I.DTMS.FATFFSVDKNGQMATNGSVIDIIANGGVFTINSVLLVAEQ
A0A410T4K3_9CAUD/90-248 ...................egnsgtvddflta-----------.......---------------.....----...TAGKRRKSEVFWTGLNIALQSgA.TV..NLIEIL..KSTPP..TFG..I.LEPFFKVSDNKLWP.F.NEDRTLNFKLNLTGAF..A.GP.SQARSITLN.FV.GTN.GNTLIQSRPEGN.V.T.DVLS.FNTFFSVDKNGVMTTNGTAVTLTANGGTFTINSVLLVAEQ
A0A2S1PG26_9CAUD/1-68 ................................-----------.......---------------.....----...---------------------.-.--..------..-----..---..-.--------------.-.----------------..-.--.-----MELT.IN.AGVnIDTLTVVRISEQ.A.S.QTIN.YNSFISVDKNGNFATNGGTLELVSSTSNFTITRVRIIAEQ
#=GC seq_cons ...............................................................................TpRhKoElhaoGlolslss.s.ss..NLlsLL..KuhsP..soG..o.LAPFFchsssKhhs.a.NsspoLhaKlslsGoa..s.uu.ousRohpls.Fs.Gos.sspLspsRssus.s.s.Dsls.FsTFFSVDKsGNlATNGuslslpSsGusFTITplhLIAEQ
//
