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Database: Pfam
Entry: Phyto-Amp
LinkDB: Phyto-Amp
Original site: Phyto-Amp 
#=GF ID   Phyto-Amp
#=GF AC   PF15438.10
#=GF DE   Antigenic membrane protein of phytoplasma
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q7M1T6
#=GF GA   25.00 25.00;
#=GF TC   165.50 34.40;
#=GF NC   20.40 19.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11782508
#=GF RT   Immunodominant membrane proteins from two phytoplasmas in the
#=GF RT   aster yellows clade (chlorante aster yellows and clover
#=GF RT   phyllody) are highly divergent in the major hydrophilic region.
#=GF RA   Barbara DJ, Morton A, Clark MF, Davies DL;
#=GF RL   Microbiology. 2002;148:157-167.
#=GF RN   [2]
#=GF RM   21799902
#=GF RT   The major antigenic membrane protein of "Candidatus Phytoplasma
#=GF RT   asteris" selectively interacts with ATP synthase and actin of
#=GF RT   leafhopper vectors.
#=GF RA   Galetto L, Bosco D, Balestrini R, Genre A, Fletcher J, Marzachi
#=GF RA   C;
#=GF RL   PLoS One. 2011;6:e22571.
#=GF DR   INTERPRO; IPR029216;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Phyto-Amp is a family of phytopathogenic wall-less bacterial
#=GF CC   antigenic membrane proteins [1]. The bacteria are limited to the
#=GF CC   phloem and pose a major threat to agriculture worldwide. They
#=GF CC   are transmitted in a persistent, propagative manner by
#=GF CC   phloem-sucking Hemipteran insects. Phytoplasma membrane proteins
#=GF CC   are in direct contact with hosts and are assumed to be involved
#=GF CC   in determining vector specificity. Phyto-Amp is thought to be
#=GF CC   one family of proteins that mediates such specificity. The
#=GF CC   proteins appear to be encoded by circular extrachromosomal
#=GF CC   elements, at least one of which is a plasmid [2].
#=GF SQ   3
#=GS AMP_ONYPE/1-195      AC Q7M1T6.3
#=GS B1VAX3_PHYAS/84-113  AC B1VAX3.1
#=GS B1VAX3_PHYAS/1-88    AC B1VAX3.1
AMP_ONYPE/1-195                 ..MQNQKNQKSLVAKVLVLF---AAVALMFVGVQVFADDKLDLNTLECKDALELTAADAADAEKVVKQWKVQNTSLNAKVTKDSVKVAVADNKVTVTPADGDAGKALSGSKILNLVGVCELNKLTLGTEKKLTLTVKDGKVDAEAGLKALKEAGAKVPATVNKDDVTFTVGKDDNANKVTVKAVDGKTTVSGQVVFEFTV.
B1VAX3_PHYAS/84-113             tl--------------------------------------------------------------------------------------------------------------------------------------------------------------------------NDAKTKVTVKAKDNDTVVAGSVELDIKA.
B1VAX3_PHYAS/1-88               ..MNNTKIQKTLVSKLAALFAIGAAVSLLFVS-NVFAAAK-ELNTFKTNQAIAITAENASNVEKVLTAWN--------KV-DDTVKVADLKDHVTVTLND----------------------------------------------------------------------------------------------------a
#=GC seq_cons                   ..MpNpK.QKoLVuKlhsLF...AAVuLhFVu.pVFAssK.-LNThcsppAltlTAtsAussEKVlptWp........KV.cDoVKVAshcs+VTVT.sD........................................................................sDstsKVTVKAhDscTsVuGpV.h-hps.
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