#=GF ID   PilA4
#=GF AC   PF18682.5
#=GF DE   Pilin A4
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF08315
#=GF GA   26.80 26.80;
#=GF TC   29.80 33.80;
#=GF NC   26.70 26.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0327
#=GF RN   [1]
#=GF RM   24218553
#=GF RT   Structure and assembly of an inner membrane platform for
#=GF RT   initiation of type IV pilus biogenesis.
#=GF RA   Karuppiah V, Collins RF, Thistlethwaite A, Gao Y, Derrick JP;
#=GF RL   Proc Natl Acad Sci U S A. 2013;110:E4638-E4647.
#=GF DR   INTERPRO; IPR041050;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in the major pilin protein PilA. PilA4
#=GF CC   binds to PilMNO forming a complex with a well-defined platform
#=GF CC   linking the cytoplasmic PilM protein to pilus subunits in the
#=GF CC   periplasm. Structure analysis indicate that it is comprised of
#=GF CC   one alpha-helix and 4 beta-sheets [1].
#=GF SQ   24
#=GS Q5SIZ2_THET8/39-117       AC Q5SIZ2.1
#=GS A0A2H5YXQ8_9BACT/38-119   AC A0A2H5YXQ8.1
#=GS A0A1W1UWG0_9DEIO/39-119   AC A0A1W1UWG0.1
#=GS A0A172T6T9_9DEIO/39-124   AC A0A172T6T9.1
#=GS A0A1W1UR87_9DEIO/28-110   AC A0A1W1UR87.1
#=GS D7CTJ1_TRURR/44-125       AC D7CTJ1.1
#=GS A0A399FCD4_9DEIN/37-123   AC A0A399FCD4.1
#=GS A0A072NAS5_9DEIO/39-119   AC A0A072NAS5.1
#=GS Q9RWW9_DEIRA/39-123       AC Q9RWW9.1
#=GS F0RQK2_DEIPM/39-113       AC F0RQK2.1
#=GS A0A1W1VQW2_9DEIO/39-119   AC A0A1W1VQW2.1
#=GS A0A1U7P578_9DEIO/46-124   AC A0A1U7P578.1
#=GS F0RLL9_DEIPM/39-124       AC F0RLL9.1
#=GS A0A1W1VJH9_9DEIO/176-267  AC A0A1W1VJH9.1
#=GS Q1IWQ2_DEIGD/39-120       AC Q1IWQ2.1
#=GS A0A399F9R5_9DEIN/37-118   AC A0A399F9R5.1
#=GS F0RLM0_DEIPM/40-124       AC F0RLM0.1
#=GS Q9RWW7_DEIRA/195-280      AC Q9RWW7.1
#=GS D7CTJ2_TRURR/40-121       AC D7CTJ2.1
#=GS A0A172T6U7_9DEIO/39-122   AC A0A172T6U7.1
#=GS Q5SIZ3_THET8/38-117       AC Q5SIZ3.1
#=GS A0A0F7JP13_9DEIO/39-121   AC A0A0F7JP13.1
#=GS A0A1W1VR72_9DEIO/502-581  AC A0A1W1VR72.1
#=GS H7GEL7_9DEIN/38-116       AC H7GEL7.1
Q5SIZ2_THET8/39-117                  ....NLAAGQSYVRNVALALEAQRD.PSTGALPTH.LTDCLSGF....--GQRPKTVT..ACTITYLNALD-.YVIEA-SLDGAA..LKKVVYKSSDG....................
A0A2H5YXQ8_9BACT/38-119              ....NTVAAQSYIRNVATAVEAERN.SLTGQLPQL.-GNCTNFV....--SNPPAFMS..NCTVSAKADSIN.FTVAASLASGAA.rYTN--------itfdsatgq...........
A0A1W1UWG0_9DEIO/39-119              ....NNTAASSMLRNAVTAAEAYRS.-ASGTTLTA.STECKDANv..lNLTALPASVT..ACQIQQNANGTVgY---STSSNNVS..YQWDGKTMK--g...................
A0A172T6T9_9DEIO/39-124              ...i-STATQAYVLDVVTGVETQRD.TVTGALPII.APSCTAAS....GNPGLPASVKtgTCQVIFGTTNKDfFVVNATTRNGTD..YTYDGTAMKFG....................
A0A1W1UR87_9DEIO/28-110              ..pd--SPARSLLVQAINAAEDHRS.-TSGTYFKV.ATDCRNSEl..lNITSFPATVT..ACRIQQTPNGTYgY-VTS-STMDKS..YQFDGTFIAQG....................
D7CTJ1_TRURR/44-125                  ....NDTAAQAYIRNCYTAVESQRD.PVTQALPTA.-ATCDALE....PGVPTPAAVT..GPGTITADGNGG.FSVAATSVTNTN..FTFDGATMTS-n...................
A0A399FCD4_9DEIN/37-123              ....NLTAAQAYVRNVATQLEAQRD.PSTGALPTG.MNTCALAN....PGAAVPAAITpgSCTITFTNNNND.FTITASSLSNA-..-----------gkstityqsqngaf......
A0A072NAS5_9DEIO/39-119              ....NESATQSYVRNTVTAVEANRD.PVTQALPTE.-TDCTELT....-GLPLPAGTA..SCAIDYDTDTDS.YTVTAAAKTGAE..FKYDGKEITK-t...................
Q9RWW9_DEIRA/39-123                  ...y-DSATTSYLRHCASALEISRD.-DLGVLPSPpPTSCEDPAl.gvNAQSKPASVK..QSQVTVTSSGTA.YTISALSQSGKT..FTYD-------qggfre..............
F0RQK2_DEIPM/39-113                  ...e-KNATRDYLATCLNAAEQKRN.FHSGELTLP.-ASCTDLV....GTSASPLTVN..TITESGGT----.YTITLTDSSGET..FT---------etlrka..............
A0A1W1VQW2_9DEIO/39-119              ....NNTAASSMLRNAVTAAEAYRS.-ASGTTLTA.STECKDPNv..lNLTALPASVT..ACQIQQNANGTVgY---STSSNNVS..YQWDGKTMK--g...................
A0A1U7P578_9DEIO/46-124              ....NNSAAQSTLRNAITAAEAARA.--NGDAVAA.NTACTAAP....INLAANPSVT..TCAVSQNNNATVgYSV---SSTGVW..YSFNGTSLAKG....................
F0RLL9_DEIPM/39-124                  ....NVTAAQAFGKECITAVEMKRD.-AQGLLPTE.-TSCLALMgkdaAPSALGGADA..DGTVAYDETNKDkYTIEVPVANGGQ..WDYDGSNWAY-t...................
A0A1W1VJH9_9DEIO/176-267             nllv----AQSLLRNAVLAAESYRF.DSNTYLKTA.-TDCKDFRi..lNIPSFPYGVT..TCRIQQTVNGTYgYVTSRRSRYD--..-----------rsyqvvyfdrsyqfdgtrvv
Q1IWQ2_DEIGD/39-120                  ....NESAAQSLLRNAVTAAESYRT.-SSGTYLNT.ATDCTNANv..lNITSYPSSVT..ACKVQQTANGTYgY---VTASTGKS..FQFDGTTIKQG....................
A0A399F9R5_9DEIN/37-118              ....NLTGAQVYVRSVATQLEATRD.PLTGALDPS.VQTCTSNF....--GPKPSSVT..ACSIAYTNNTND.FVVTSTLSNAGKstLTYQS------esgaf...............
F0RLM0_DEIPM/40-124                  ....NDQAAIAYLRHCVTSIEMVRK.PGTLALPDG.ITHCRDDEl.rpAAMGEVSAVR..SDRVDVDPTTGQ.YTIEVVSAAGKT..FHYDGKV----ivf.................
Q9RWW7_DEIRA/195-280                 ....NDSATQSYIRNCYTAVEVARG.-ADGRLPAA.-GNCDSTAnlgtNAVATPGAIT..AAGAYSLDGTGSkFAVTATSVTNKT..FCFDGAKMGEG....................
D7CTJ2_TRURR/40-121                  ....NDAATKAYIHHVIKGVEAERD.IATMTLPAA.-KTCAALA....HLRADPLSVA..SCVYDPDVANET.YTISATSVTGKR..FYYNGAEVVQ-l...................
A0A172T6U7_9DEIO/39-122              ....NDTATQSFIRNVVTGVETQRD.SVTGALPAT.APTCIVAT....GKTALPASVK..SCAIILGTTNKDaFVVNASSINNTD..YTYDSKEVKTG....................
Q5SIZ3_THET8/38-117                  ....NTTAAQAYVRNVATAVEAERD.PTTGALPQL.PQACDQFV....--ANPPASVT..QCNVTANNDGVN.FTVTA-QLTGAR..YGSVSFDSSTG....................
A0A0F7JP13_9DEIO/39-121              ....NESAAQSFVRNTLTAVETKRD.SVSGKLDTS.ITDCKVAQ....EKTEEPAGVT..SCTIIYGTKDN-.YGVTLAMQDGKT.fFNYDGVNIAKG....................
A0A1W1VR72_9DEIO/502-581             ....NNSAAQSLARNMVTMVEIAKStSGSGNLYTT.ATDCTPDL....-IPSLPSNIL..LCQVKQDANGT-.YSLVR-SSTNAY..FHFNGKA----teg.................
H7GEL7_9DEIN/38-116                  ....NDTAAVAYTRNVATEIEATRD.PATGQVTAT.--TCPTSV....---TKPAVVQ..NCTVTTTDNNNN.FRVTVTYSGGSKttVTYDSST----gql.................
#=GC seq_cons                        ....NsoAAQualRNslTAlEspRs..soGsLsss..ssCpsss.....hsuhPuuVs..sCslphssssss.Yslsusossusp..apasutt........................
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