#=GF ID   PilN_bio_d
#=GF AC   PF18222.5
#=GF DE   PilN biogenesis protein dimerization domain
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF03582
#=GF GA   25.00 25.00;
#=GF TC   25.80 48.50;
#=GF NC   23.90 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0331
#=GF RN   [1]
#=GF RM   24218553
#=GF RT   Structure and assembly of an inner membrane platform for
#=GF RT   initiation of type IV pilus biogenesis.
#=GF RA   Karuppiah V, Collins RF, Thistlethwaite A, Gao Y, Derrick JP;
#=GF RL   Proc Natl Acad Sci U S A. 2013;110:E4638-E4647.
#=GF DR   INTERPRO; IPR040888;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in PilN type IV pilus biogenesis protein
#=GF CC   present in Thermus thermophiles. PilN is an integral inner
#=GF CC   membrane protein needed for the formation of type IV pilus. This
#=GF CC   domain forms a dimer which is mediated by symmetric contacts
#=GF CC   between residues in alpha-1, beta-1, beta-3 and alpha-3 [1].
#=GF SQ   28
#=GS A0A072N9S4_9DEIO/97-198  AC A0A072N9S4.1
#=GS A0A318SCN0_9DEIO/97-199  AC A0A318SCN0.1
#=GS E8U803_DEIML/97-197      AC E8U803.1
#=GS A0A418VAX1_9DEIO/97-198  AC A0A418VAX1.1
#=GS A0A399EAI8_9DEIN/97-201  AC A0A399EAI8.1
#=GS D7CWU7_TRURR/97-202      AC D7CWU7.1
#=GS C1CX18_DEIDV/97-198      AC C1CX18.1
#=GS A0A0X8D8R3_9DEIN/97-201  AC A0A0X8D8R3.1
#=GS F2NQQ6_MARHT/97-200      AC F2NQQ6.1
#=GS A0A0F7JLI9_9DEIO/97-198  AC A0A0F7JLI9.1
#=GS H8GZ62_DEIGI/97-198      AC H8GZ62.1
#=GS Q9RW98_DEIRA/97-192      AC Q9RW98.1
#=GS F0RLE5_DEIPM/99-201      AC F0RLE5.1
#=GS A0A1W1VPT7_9DEIO/97-198  AC A0A1W1VPT7.1
#=GS E4U915_OCEP5/97-200      AC E4U915.1
#=GS A0A2Z3JKK8_9DEIO/98-190  AC A0A2Z3JKK8.1
#=GS A0A511N8H4_DEIC1/97-194  AC A0A511N8H4.1
#=GS D7BEI5_MEISD/97-201      AC D7BEI5.1
#=GS A0A399FE50_9DEIN/97-201  AC A0A399FE50.1
#=GS A0A841I0C8_9DEIO/97-200  AC A0A841I0C8.1
#=GS Q5SII9_THET8/97-201      AC Q5SII9.1
#=GS A0A221SXA5_9DEIO/97-198  AC A0A221SXA5.1
#=GS A0A7C9HWC3_9DEIO/97-198  AC A0A7C9HWC3.1
#=GS A0A172T7H2_9DEIO/97-198  AC A0A172T7H2.1
#=GS A0A1U7NVU9_9DEIO/97-214  AC A0A1U7NVU9.1
#=GS A0A399EZ43_9DEIN/97-206  AC A0A399EZ43.1
#=GS Q1IXL3_DEIGD/97-198      AC Q1IXL3.1
#=GS L0A7T1_DEIPD/97-200      AC L0A7T1.1
A0A072N9S4_9DEIO/97-198             .........WTNDLAAFSAQLPSGGG........VALTSMTVRPLDAAALGNLQQTGVYAGKNVVREFDLSGTARSQQSVVNFLNAFENSPSFAVNFRGVQREGDSD................LYTFTASVGLVG...
A0A318SCN0_9DEIO/97-199             .........WSADLARFVRQLPTSNTp......iIALTNVSMRMPQLAAAP-GGANAPYDGKAVTKELVLSGLARSSDALVRLVNTFENAPEFGVQFQNAARDPNTG................EYTFAVTVGMIG...
E8U803_DEIML/97-197                 .........WSSDLARFVNQIPTVKD........VALTSLTVGTATTAATP-VGGATPFDGKAISKTFTLNGRARSTQALVRFLNAYERSPEFGITFNNATRDEQTQ................DYTFNAVVGLVA...
A0A418VAX1_9DEIO/97-198             .........WSNDLAVFSREIPASSG........VALTKLTMRDKKPEELTTDQGNGIFIGKAVRRELDLSGAASSQQAVINFLNTFENSPGFGVNFQGMERDDKSG................AYTFNARVGIVG...
A0A399EAI8_9DEIN/97-201             .........WSDNLALVINQIPREGRr.....fgIALRSIGTRALTPQEVQANVQNGVYDGKPVNIEFNLQGEAIGQNALIRFVEAFESSPRFGINFQNASLDQQRQ................LYTFGATVGLV-s..
D7CWU7_TRURR/97-202                 fseqlfaml--------ETRPPAREDpa....trMAFQTLEMRALDAATSEQRRAEGVYEDLTAVVEMDVAGVAGSAGVVADYVRELQRAPDFGVMLRDLTREE-SG................FYTFNLTIGA--al.
C1CX18_DEIDV/97-198                 .........WSNDIAAFSAELPTSSG........VSVKSMSVRPVDATALSTQQQGGVYVGKNVVREFDLSGTASSQQAVVNFLNTFENSPNFGVNFKNLQREEESG................QYTFAATVGIVG...
A0A0X8D8R3_9DEIN/97-201             .........WSQYLAAFINQIPKAGGr.....leVALRSVSARALSEEEAARLAQEGTYDGKRVRVEFALQGEALSREALVRFIRAFETSPRFGIEFQGASLDEGRG................LYTFSARVGVTG...
F2NQQ6_MARHT/97-200                 .........WSDHLARLINQIPRENDq.....frVALATIAAQPVPPQTQEAYMAQGLYDRKPVRVEFRVEGEALEEEALIRFVQAFETSPAFGINFHRSSRDE-QG................MLRFNATIGLVA...
A0A0F7JLI9_9DEIO/97-198             .........WTNDLASFTAQLPGGSG........VALKSMTIRPLDAAALATQQQSGVYTGKNVTREIELSGSASSQQAVVNFLRTFENNPNFGVNFRSLQSEGETG................QYSFNATVGLV-k..
H8GZ62_DEIGI/97-198                 .........WSNDLAAFSTQLASAPG........VSVSSLTMRPLDAGALATSQQNGIYTGKNVRRELDLSGAASSQQAVINFLNTYENDPGFGVNFKSLQRDARSG................NYTFAATVGVVG...
Q9RW98_DEIRA/97-192                 .........WSNDLASFVERVP--GN........VVFSNVNMSTVAPGAEPSLA----YAGKPVTRQLDLTGSARSQEAIVGFLNAFETDSNFGVDFKGMQHDATNG................IYTFTASIGVVG...
F0RLE5_DEIPM/99-201                 .........WSNDLAAFTAQLPAGGS........VALDSLDMHTATQQSAD-MQQSGV-EGGSVSREFTLTGTATTAQAVVDLLNAFESNPKFGIVFQGMQRKEPDNe.............asPYTFSASVGVAG...
A0A1W1VPT7_9DEIO/97-198             .........WTNDVAAFSAQLPRSNG........VAITSLNMKSLEPTALATLQQNGIYAGKNVVREIALTGTALSQQSVVNFLKAYENSPSFGVNFQGLQRDTTAS................RYTFTASVGLV-n..
E4U915_OCEP5/97-200                 .........WSDNLARFINQIPRRGGr.....feVFLRSVNTRLVPQETRANLAEQGLYDRKPVAVEFNLQGEARNENALARFVQAFEDNPNFGINFQQGSLNE-NG................GFDFTATVAIT-e..
A0A2Z3JKK8_9DEIO/98-190             .........WSTDLARFVSQLPQSGG........VALSALNMHPSAV--------ASLYNGKPASKEFDLSGSALSTAALVNFLNAYDAD-NYGVNFKSTQRNPETN................NYTFSATVG---qld
A0A511N8H4_DEIC1/97-194             .........WRGDIERFVSQIPTGSSn.....ptISLNTLGVS---MPTAE----GPVGDGRPASKVMTIQGTAKSNQALIDFVKAFEDSQDFAIQFQDASKQQDTS................NYNFTVNVNLI-k..
D7BEI5_MEISD/97-201                 .........WSDNIATFVNQIPRENGr.....fgVALRSIGASLRGQGNQPAPGGENLYDGKPVKVEFSLQGEALGQAQLVRFIEAFESSPRFGINFQQATLDPNRG................LYTFSATVGMVE...
A0A399FE50_9DEIN/97-201             .........WSDDLALVINQIPREGKg.....fgVALKSISSKALTPQEVSAGTANGAYDGKPVNVEFALQGQALGQNALIRFVQAFESSDRFGINFQQANLDQNSG................LYNFGATIGLIA...
A0A841I0C8_9DEIO/97-200             .........WSTDLARFTRRIPQSGSt.....pvIALNTLSMQAVNPGDTSSTP-SVGYDGKTIRRTFTLQGRAASSAALVNFVSTFERSSDFGVQFQNAQREEDTG................DYIFSVSIGMA-d..
Q5SII9_THET8/97-201                 .........WSQYLAAFINQIPRAGGr.....leVALRSVSARALSEEEAARLAQEGTYDGKRIRVEFALQGEALSREALVRFIRAFETSPRFGIEFQGASLDEGRG................LYTFSARVGVTG...
A0A221SXA5_9DEIO/97-198             .........WSNDIASFTRRLPQSSG........VAVKTMTIKPMDAAQLTSNQQSGIYVGKSVTREIDITGQATGQQAVVNFLNTYENDPNFGVNFKSMQKDGETS................DYTFSATVGVVG...
A0A7C9HWC3_9DEIO/97-198             .........WTNDLAAFTAQLPTGGG........VALQSMAVKAVDANALTALQQTGVYTGKNVTREIDLTGTASSQQAVVNFLRTFENNPNFGVNFRSLQSEGETS................NYTFNASVGIV-q..
A0A172T7H2_9DEIO/97-198             .........WSNDLATFTAQLPAGGN........VALTSMNVRPVEATALTGLQQTGVYIGKNVQREIELSGTARSQQAVVNFLNAFETNPKFGVNFRSLQNDQATG................TYTFAATVGLVG...
A0A1U7NVU9_9DEIO/97-214             .........WTNDLAAFTSQLPNDGS........LAVNSMTIRNLDAGNLITLQQGGIYMGKAVTREIDLSGTATSQQAVVNFLKLYEDNPNFGVNFKSLQSDAQGGaaligagqngaagakkRYTFTASVGIVG...
A0A399EZ43_9DEIN/97-206             .........WSDYLAAVINQIPRSSSapsgsafgVNLKSIGTKLLTPSEVQNAVRTGAYDGKSARVEFDLRGEALNERELIRFVDAFESSPRFGINFRDTSLDQQRG................VYTFSAVIGLV-d..
Q1IXL3_DEIGD/97-198                 .........WTNDLAAFAAQLPSGGG........VAITSMNIKALDSAALASLQQSGIYAGKNVVREFDLSGTARSQQSVVNFLNAFENSPNFAVNFRSLQREGDTG................RYTFAASVGLVA...
L0A7T1_DEIPD/97-200                 .........WSDDLARFVRQLPSGDAp......vVALSSLSMRAVDAGAQQAAAQNGLYDGKAVSKEVQLSGKARSSAALVQFVNAFEQAPDFGVQFQNMQREQAGG................QYSFSATVGMVG...
#=GC seq_cons                       .........WSsDLAsFssQlPpuuu........VALpSlsh+slsssshsshtpsGlYsGKsVs+EhsLsGpApSppAlVsFlpAFEsuPsFGVNFpshp+-ppsG................tYTFsAoVGlVu...
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