#=GF ID   Pneumovirus_M2
#=GF AC   PF06436.15
#=GF DE   Pneumovirus matrix protein 2 (M2)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_2318 (release 10.0)
#=GF GA   25.00 25.00;
#=GF TC   128.00 127.90;
#=GF NC   19.90 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12692207
#=GF RT   Identification of amino acids that are critical to the
#=GF RT   processivity function of respiratory syncytial virus M2-1
#=GF RT   protein. 
#=GF RA   Zhou H, Cheng X, Jin H; 
#=GF RL   J Virol 2003;77:5046-5053.
#=GF DR   INTERPRO; IPR009452;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Pneumovirus matrix glycoprotein
#=GF CC   M2 sequences. This family functions as a transcription
#=GF CC   processivity factor that is essential for virus replication [1].
#=GF SQ   8
#=GS M21_HRSVA/29-187         AC P04545.1
#=GS Q5MKN3_9MONO/28-176      AC Q5MKN3.1
#=GS M21_HRSVB/29-187         AC O42050.1
#=GS M21_MPV15/28-176         AC Q5MKM1.1
#=GS A0A077SGE7_9MONO/29-185  AC A0A077SGE7.1
#=GS M21_AMPV1/29-183         AC Q2Y2M2.1
#=GS M21_BRSVA/29-186         AC P29792.1
#=GS M21_HMPVC/29-183         AC Q6WB97.1
M21_HRSVA/29-187                    EWPPHALLVRQNFMLNRILKSMDKSIDTLSEISGAAELDRTEEYALGVVGVLESYIGSINNITKQSACVAMSKLLTELNSDDIKKLRDNEELNSPKIRVYNTVISYIESNRKNNKQTIHLLKRLPADVLKKTIKNTLDIHKSIT..INNPKESTVSDTN--dh....
Q5MKN3_9MONO/28-176                 EWPLKTLMLRQNYMLNRIYRFLDTNTDAMSDVSGFDAPQRTAEYALGTIGVLKSYLEKTNNITKSIACGSLITVLQNLDVGLVIQARDSNTEDTNYLRSCNTILSYIDKI-HKKRQIIHILKRLPVGVLCNLIQSVISIEEKIN..---------------ssmkte
M21_HRSVB/29-187                    EWPPHALLVRQNFMLNKILKSMDKSIDTLSEISGAAELDRTEEYALGIVGVLESYIGSINNITKQSACVAMSKLLIEINSDDIKKLRDNEEPNSPKIRVYNTVISYIESNRKNNKQTIHLLKRLPADVLKKTIKNTLDIHKSII..ISNPKESTVNDQ---ndq...
M21_MPV15/28-176                    EWPLKTLMLRQNYMLNRIYRFLDTNTDAMSDVSGFDAPQRTAEYALGTIGVLKSYLEKTNNITKSIACGSLITVLQNLDVGLVIQARDSNTEDTNYLRSCNTILSYIDKI-HKKRQIIHILKRLPVGVLCNLIQSVISIEEKIN..---------------ssmkte
A0A077SGE7_9MONO/29-185             SWPDHVLLVRINCMLNQLQRNTDRT-DGLSLISGAGREDRTQDFVLGSANVVQGYIDGNATITKSAACYSLYNIIKQLQENDVKASRDTMLDDHKHVALHNLVLSYIDMS-KNPASLINSLKRLPKEKLKKLAK--VIVQLSAGpeVENASGHPMQ-----kgdsg.
M21_AMPV1/29-183                    SWPDRYLLLRSNYLLNQLLRNTDRS-DGLSLISGAGRDDRTQDFVLGSTNVVQNYIDNNENITKASACYSLYNIIKQLQETDVRQARDNKVDDSKHVALHNLVLSYMEMS-KTPASLINNLKKPPKEKLKKLAK--LIIELSAG..VENDSTAAMQDSANS......
M21_BRSVA/29-186                    EWPPHALLVRQNFMLNKILKSMDRNNDTLSEISGAAELDRTEEYALGVIGVLESYLSSINNITKQSACVAMSKLLAEINNDDIKRLRNKEVPTSPKIRIYNTVISYIDSNKRNTKQTIHLLKRLPADVLKKTIKNTIDIHNEIN..GNNQGDINVDE----qne...
M21_HMPVC/29-183                    SWPDRYLLIRSNYLLNQLLRNTDRA-DGLSIISGAGREDRTQDFVLGSTNVVQGYIDDNQSITKAAACYSLHNIIKQLQEVEVRQARDSKLSDSKHVALHNLILSYMEMS-KTPASLINNLKRLPREKLKKLAK--LIIDLSAG..ADNDSSYALQDS---esi...
#=GC seq_cons                       EWPs+sLLlRQNaMLN+ILRshD+s.DuLS-ISGAuc.DRTpEYALGolGVLcSYI-ssNNITKuuACsSLhslLppLsssDV+puRDschsDSs+lRlaNTVLSYI-ps.Kss+QlIHlLKRLPs-VLKKLIKsslsIcpSIs..hpNspp.shp-....ps....
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