#=GF ID   PorB
#=GF AC   PF11565.12
#=GF DE   Alpha helical Porin B
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   pdb_2vqg
#=GF GA   22.50 22.50;
#=GF TC   22.50 22.70;
#=GF NC   21.80 22.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Corynebacterial_porin_B
#=GF RN   [1]
#=GF RM   18462756
#=GF RT   A putative alpha-helical porin from Corynebacterium glutamicum. 
#=GF RA   Ziegler K, Benz R, Schulz GE; 
#=GF RL   J Mol Biol. 2008;379:482-491.
#=GF DR   INTERPRO; IPR021114;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Porin B is a porin from Corynebacterium glutamicum which allows
#=GF CC   the exchange of material across the mycolic acid layer which is
#=GF CC   the protective nonpolar barrier. Porin B has an alpha helical
#=GF CC   core structure consisting of four alpha-helices surrounding a
#=GF CC   nonpolar interior. There is a disulphide bridge between helices
#=GF CC   1 and 4 to form a stable covalently bound ring [1]. The channel
#=GF CC   of PorB is oligomeric [1].
#=GF SQ   29
#=GS A0A1F1UX44_9CORY/22-136  AC A0A1F1UX44.1
#=GS A0A6B8VBE5_9CORY/32-127  AC A0A6B8VBE5.1
#=GS C3PFA5_CORA7/21-128      AC C3PFA5.1
#=GS A0A097IET1_9CORY/30-120  AC A0A097IET1.1
#=GS A0A0G3H6C3_9CORY/23-131  AC A0A0G3H6C3.1
#=GS Q8FQT1_COREF/43-151      AC Q8FQT1.1
#=GS M1NWX6_9CORY/16-119      AC M1NWX6.1
#=GS A0A177IRS5_9CORY/26-130  AC A0A177IRS5.1
#=GS A0A0K1R948_9CORY/18-121  AC A0A0K1R948.1
#=GS A0A1F1KUU0_9CORY/21-127  AC A0A1F1KUU0.1
#=GS A0A6B8W4K1_9CORY/19-133  AC A0A6B8W4K1.1
#=GS A0A3M8K706_9CORY/34-130  AC A0A3M8K706.1
#=GS A0A376GNR2_CORST/20-131  AC A0A376GNR2.1
#=GS A0A1Q2HY80_9CORY/42-140  AC A0A1Q2HY80.1
#=GS A0A076NSV7_9CORY/19-121  AC A0A076NSV7.1
#=GS Q8FQT0_COREF/53-150      AC Q8FQT0.1
#=GS A0A2A9DRN0_9CORY/24-136  AC A0A2A9DRN0.1
#=GS A0A1L7D486_9CORY/26-133  AC A0A1L7D486.1
#=GS Q8NRS3_CORGL/28-126      AC Q8NRS3.1
#=GS A0A2S0WFA1_9CORY/33-124  AC A0A2S0WFA1.1
#=GS A0A2S9Z4W5_9CORY/36-120  AC A0A2S9Z4W5.1
#=GS A0A0F6QW80_9CORY/19-126  AC A0A0F6QW80.1
#=GS A0A4T1ZQ95_9RHOB/26-125  AC A0A4T1ZQ95.1
#=GS A0A1L7CF21_9CORY/37-122  AC A0A1L7CF21.1
#=GS A0A1H1M680_9CORY/35-123  AC A0A1H1M680.1
#=GS A0A0B6TKB6_9CORY/15-135  AC A0A0B6TKB6.1
#=GS Q8NRS4_CORGL/34-137      AC Q8NRS4.1
#=GS A0A133ZE06_9CORY/30-134  AC A0A133ZE06.1
#=GS A0A1H9WB62_9CORY/21-123  AC A0A1H9WB62.1
A0A1F1UX44_9CORY/22-136             ......aapaaqaqdatsl------..---LQLV.NGNV.K.TMNCSTLRVTLN.....GT.....G..V.AGKD......T......TRQQLVNNLNGKIG.........DSIAL...RVMSGG-....----TVQAVADRALECGIVKPDpvqdwaklrgssqtnipPQLQ...Q...LSSNL--dl.......................
A0A6B8VBE5_9CORY/32-127             ...........ldtnylag------..-------.----.-.-ADCASLNATLT.....SL.....N..L.VTGP......T......TKSELAAKIKSTGT.........EVLGG...-LNMGGEeaqiMVNKAAMDASNRALECGIVKED.................PKV-...-...-------mgsiempqqiadlk...........
C3PFA5_CORA7/21-128                 ..............patas--AASL..TELGGFL.SQGI.Q.SADCNTLRSTLT.....LI.....D..Q.STEGelltpdT......TRNQLSKNLTALGNsae..lgplAFAAV...KY-----....-----AGQTADRALECKIVKED.................TI--...-...-------atggtglsskiad............
A0A097IET1_9CORY/30-120             ........gntvallvlan------..-------.-GQI.A.TADCGLVGGVLR.....GT.....G..L.VNET......T......TRSELVTSLHRTLA.........GDIQT...KL-----....ITAQTIGVIGDRALECGVVKAD.................PNVP...A...GSSQLM-d........................
A0A0G3H6C3_9CORY/23-131             ..apaasafslgdiltgtg------..-------.-QAV.N.ALNCKDLDNILN.....TA.....K..L.KDGN......T......TRNGLVKNISGLTK.........EATGN...NI-MLSL....LGGNTAGKVADRALQCKLVKEDpkel.........fpgsSQVN...D...-------mvaqlss..................
Q8FQT1_COREF/43-151                 ..ltatiapaqaqnadivs------..-----GI.NNLI.D.TFDCDLLRTGLT.....QT.....G..L.VTPE......T......TRSELAATLRTTANl.......gEI-DV...AFAFVG-....--SAYAGRIADRAQTCGIVQPDpeq...........dilTQLQ...N...LSSNLSS.........................
M1NWX6_9CORY/16-119                 ................aat---ALA.pAASAQNL.GEEFiA.DLNCDHLETALT.....TL.....D..F.VDED......T......TRNELAAEIREFGD........iEIDLG...PL-PSVV....VQAYYAGQIADRALECGIVDED.................PA--...-...-------spfaasseflenl............
A0A177IRS5_9CORY/26-130             ....aldlgnigaadklat------..-------.-GLI.N.NAKCSDVRGALD.....TLna.tnGgrI.YNKE......T......TRNELVQNLRQASGtkgnptdltTLAI-...-------....--TKYTGQVADKALKCGIVKPN.................PATP...F...GSSELN-t........................
A0A0K1R948_9CORY/18-121             ...apaaaadnslvqlirv------..------V.NGEV.E.TADCNTLGAALR.....VA.....G..L.VDAD......T......TRSQLVRKVNGAIG.........DDSSL...RL-----....VTAPTVNKLGDRALQCGVVKPDpv............tpqSQAI...E...FVSQL--ssr......................
A0A1F1KUU0_9CORY/21-127             ........apaaqaapsfl------..-----DLgSQLI.K.SADCNTLRTTLH.....AIdtttsG.eL.LTPE......T......TRNQLSRNLRELNP.........NGQTL...--SPIQL....AATKFAGETADRALKCGIVKQD.................TMLTggtG...LSSQ---lgd......................
A0A6B8W4K1_9CORY/19-133             .......aivapnaaaqdg------..----NVL.DNIL.A.NLSCEQVDTGIK.....TV.....G..A.YESDha.tatT......TRNELATNIRELNQ.........DALGTllgGVPFVGL....FQAQIANSVADKALGCDLVIQD.................PALG...-...-------ssdfagildslssr...........
A0A3M8K706_9CORY/34-130             .................ap--AASA..STSSDDL.NLNL.DiNWECAALGLVLD.....QF.....D..L.LNDG......T......TYSQLIDNINNSVD.........STLAG...-------....---VAAIPVADRALACGLISED.................PLLS...G...GSS----qaiqglssgss..............
A0A376GNR2_CORST/20-131             tpaaaqaqnllgdinslaa------..-------.-QLI.S.GADCGTVRTALT.....LIdqntpG.vL.LDEN......T......TRNQLAHNLQNLGG.........ERKAQ...-ISPLTI....AAIKYSGLTADRALTCGIVKQD.................TLLTggtG...LSSQIS-d........................
A0A1Q2HY80_9CORY/42-140             .........tdlgtyvelt------..----KVL.NGEI.K.TANCDTLSTTLK.....LT.....K..M.VDGE......T......TRSTLVQNLNKVVG.........ENSVL...RL-----....ATAPTVNALGDRALECGIVKADpv............tplDQAV...K...LSSQLSS.........................
A0A076NSV7_9CORY/19-121             ...aapanaqtnyaelvrv------..------L.NGNV.K.TMDCNALRTVVR.....GA.....G..L.ANEN......T......TRSEFVGNVNKAVG.........EDAAL...RL-----....VAAPTVNTLGDRALECGIVKPDev............tplNQAI...A...MSSQMS-s........................
Q8FQT0_COREF/53-150                 ...................AGPASA..VSSSDEL.SDRF.D.WVGCPIVEASLA.....FY.....G..L.PEEG......M......RNNQLAAALEEKNA.........NFAAY...-FEGGGD....WNAQASADYADRAQKCGIVEPN.................TAIE...N...ASSNLND.........................
A0A2A9DRN0_9CORY/24-136             ..aaqanplelfgaadqli------..-------.----.A.AAPCNTLGDILR.....GT.....G..V.LGAD......T......TRGQLVESINK-GV.........NSQNN...-DPLVSL....LTGKYSNQIANKAQQCGLVKADp...............vH---...-...-------pllagssqlpepvkqtltqltalss
A0A1L7D486_9CORY/26-133             ........aqtlevlgald------..----KVV.SQTI.E.SSSCDTVKTVLTsidasTP.....G..VlMDAN......T......TRSQLANNLRALGN........sNVSAA...GA--LAL....PAIRYSNKTADKAVACGLVKPD.................PASN...DpfgLSSKFN-d........................
Q8NRS3_CORGL/28-126                 ...................SDFANL..SSTNKEL.SPQY.N.WVACGILEGGLK.....AA.....G..V.LEEG......Q......YNRELAEAIAAKGE.........GFWTT...QFPQIGD....WNEDQAAALADRAQTCGLVKAD.................TYLS...E...LSSNFSS.........................
A0A2S0WFA1_9CORY/33-124             ...............larv------..------L.NGGI.A.TADCGAVFTGLT.....AT.....G..L.VGPE......T......TRGELVASLNKAVG.........DEASL...RL-----....VAAPTINTIGDRALECNVVKPDpv............tplG---...-...-------qaidfasqlssq.............
A0A2S9Z4W5_9CORY/36-120             ...............gtnt------..-------.---A.E.NLSCQDVKSGLE.....TL.....G..L.YSPE......D......TRITLETKIKAKAT.........DLAGN...N-AVIAA....AAAKVGNDVSGKAEECGLIKKD.................P-IA...L...LSSQLG-s........................
A0A0F6QW80_9CORY/19-126             ...apvanaqtlgdldkla------..-------.SQAI.A.TADCRVLKTTLD.....TV.....G..R.ATGN......QligpetTRNQLARNLQALNGt.......pR----...-LDMLGL....AVIKYSGTAADRALTCNLVKPDp..............tvPGLA...Q...LSSLLND.........................
A0A4T1ZQ95_9RHOB/26-125             ...................AQTANV..VEIAKLV.NGGI.A.TADCGAVSTGLK.....ST.....G..F.VGPE......T......TRGELVASLTKAVG.........DDATL...RL-----....VSASNINTIGDRALECGVVKPDp...............vTPLN...Q...-------aiafasqlssq..............
A0A1L7CF21_9CORY/37-122             ...............gtnt------..-------.---A.N.ALTCDDTKALLE.....GF.....G..L.LDPN......D......TRESLRTKTATKIA.........AVAGQ...-LDQSGV....VGAKVSTDLAARADECGLVKKD.................-QLS...Q...LSSQMG-ss.......................
A0A1H1M680_9CORY/35-123             .............kivngn------..-------.---V.A.TADCGLVGTALR.....AT.....G..F.VTDQ......T......TRSGLVTSLNKAIG.........DDAAL...RLVASG-....----TISAVGDRALECGVVKPDpe............tpvDQAL...K...LSSQLSS.........................
A0A0B6TKB6_9CORY/15-135             ..............avagl---APA..ASAQTDLvANAI.A.AADCRLVGPALK.....TL.....F..D.IDDN......T......TRSDLAKQIRDEAK.........PWTIT...-DPSTYL....VSAQYAGQIADMAVECGTVKPD.................PELF...P...GS-----sipglenipnindvqdilenlsstl
Q8NRS4_CORGL/34-137                 ...................ALTASLtpSASAQDF.NQII.D.NFDCGILQTAIY.....TT.....G..L.AHEN......S......TRSELAANLRNSAAvgql.dfplNIAAT...GY-----....-----SERIANRALTCGIVKEDpq............dflSQLQ...L...LSSNLSS.........................
A0A133ZE06_9CORY/30-134             .........gtllgadaia------..-------.SGVI.N.TVDCGTLKTVLQgidsaTE.....G.eL.LTET......T......TQSQLAKGLQGLGK.........VEGTT...-NPALAL....AAVKYSTQTAQRAQACGIVKAD.................AP--...-...-------gsfglssqletvlp...........
A0A1H9WB62_9CORY/21-123             ...........aapasaqt----NV..LSLINTI.NSGI.E.TVDCGTLEAGLR.....GV.....G..L.IDDN......T......TRSELVKDLNNLVG.........DDASI...KL-----....ISAPTINTVGDRALECKIVKADp...............vTPVD...Q...-------aiafsshmss...............
#=GC seq_cons                       ...............shts..............h.st.l.s.sscCsslcssLp.....sh.....G..l.lsss......T......TRspLspslpphss.........s.ssh....h.........hssthusplADRALpCGlVKsD.................stl....t...hSS....t........................
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