#=GF ID Pox_polyA_pol_N
#=GF AC PF12630.11
#=GF DE Poxvirus poly(A) polymerase N-terminal domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Structure
#=GF GA 27.00 27.00;
#=GF TC 28.50 35.70;
#=GF NC 26.80 26.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 16678106
#=GF RT Crystal structures of the vaccinia virus polyadenylate
#=GF RT polymerase heterodimer: insights into ATP selectivity and
#=GF RT processivity.
#=GF RA Moure CM, Bowman BR, Gershon PD, Quiocho FA;
#=GF RL Mol Cell. 2006;22:339-349.
#=GF DR INTERPRO; IPR024398;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found at the N-terminus of the pox virus Poly(A)
#=GF CC polymerase protein [1]. According to SCOP this domain contains a
#=GF CC helix-hairpin-helix motif.
#=GF SQ 42
#=GS D3IZG5_9POXV/2-105 AC D3IZG5.1
#=GS PAP1_VACCT/11-117 AC Q9JFD9.1
#=GS PAP1_CPRVZ/1-106 AC Q070J7.1
#=GS A0A1V0QGS9_CNPV/3-110 AC A0A1V0QGS9.1
#=GS A0A2C9DT05_9POXV/4-110 AC A0A2C9DT05.1
#=GS A0A097IVQ4_9POXV/1-108 AC A0A097IVQ4.1
#=GS PAP1_YLDV/1-108 AC Q9DHT0.1
#=GS PAP1_HSPV/11-117 AC Q0GP30.1
#=GS PAP1_DPV84/1-108 AC Q08FE1.1
#=GS PAP1_VAR67/11-117 AC P0DOM1.1
#=GS PAP1_FOWPN/3-110 AC P0DTA7.1
#=GS A0A1L3IZE3_9POXV/1-108 AC A0A1L3IZE3.1
#=GS PAP1_CAMPS/10-117 AC Q8QQ67.1
#=GS Q6TVV2_ORFSA/2-105 AC Q6TVV2.1
#=GS A0A1B3B608_LSDV/1-109 AC A0A1B3B608.1
#=GS PAP1_DPV83/1-108 AC Q08FW1.1
#=GS B2CWD4_9POXV/1-108 AC B2CWD4.1
#=GS PAP1_MYXVL/1-108 AC Q9Q8R9.1
#=GS A0A7H0DN36_MONPV/10-117 AC A0A7H0DN36.1
#=GS A0A2U9QHI8_9POXV/1-108 AC A0A2U9QHI8.1
#=GS Q1HTS9_9POXV/1-107 AC Q1HTS9.1
#=GS PAP1_FOWPV/3-110 AC P0DTA8.1
#=GS PAP1_VACCC/11-117 AC P21079.1
#=GS PAP1_SWPV1/1-108 AC Q8V3R4.1
#=GS G3EIB3_9POXV/1-109 AC G3EIB3.1
#=GS PAP1_CNPV/3-110 AC Q6VZL8.1
#=GS PAP1_VACCW/10-117 AC P23371.2
#=GS A0A1B1MRC6_9POXV/1-108 AC A0A1B1MRC6.1
#=GS A0A0M3ZRP2_9POXV/3-110 AC A0A0M3ZRP2.1
#=GS W6JLK0_9POXV/2-102 AC W6JLK0.1
#=GS F1AWV9_ORFV/2-105 AC F1AWV9.1
#=GS A0A6B9R1Y0_9POXV/3-110 AC A0A6B9R1Y0.1
#=GS A0A3F2YKI5_SHEVT/1-109 AC A0A3F2YKI5.1
#=GS Q9YVU9_MSEPV/2-97 AC Q9YVU9.1
#=GS PAP1_MCV1/1-108 AC Q98199.1
#=GS A0A220T698_9POXV/3-110 AC A0A220T698.1
#=GS H6TA27_9POXV/1-108 AC H6TA27.1
#=GS PAP1_YMTV5/1-108 AC Q6TUY0.1
#=GS PAP1_RFVKA/1-108 AC Q9Q944.1
#=GS A0A223FMP0_9POXV/3-110 AC A0A223FMP0.1
#=GS Q0NPF3_9POXV/10-117 AC Q0NPF3.1
#=GS A0A223FN92_9POXV/3-110 AC A0A223FN92.1
D3IZG5_9POXV/2-105 ...........ap------PVIEEYLGARPSMERCVLLRAQRRNMTRVLNFDRKLFLSLVVKSRRRFF.KK.LGGS.EKEIAARIEEYFSRQR.RLEKLGQILTVLELQSVIVSEFTRTLGSLTT.....
PAP1_VACCT/11-117 .........pnit-----LKIIETYLGRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFF.SD.VDTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
PAP1_CPRVZ/1-106 .............MNNR--ELINRYLGKTADQPIYYALFHKVGKIKQILNFDLNVFLKLLLKNRDRFL.RE.NKQP.TAEIKRRLTHYFTKQH.RVRKVGKILSIVEFQHVIVTTFTRVLGVLTI.....
A0A1V0QGS9_CNPV/3-110 ...........kr--QEITNIIAQYLGRRPVPKEYDILKNQIIKLNKIINFNKDTFFFLIKKSKYTFF.KN.YDVT.DEIIQKRIDEYFTKQK.KAKKLGNLLAIIELQKLLVCSFTKTLGILTT.....
A0A2C9DT05_9POXV/4-110 ...........ad--RRSLDVISTYLGKAPTVEQYHVLRRQVGNISKVLKFDKDIFFSLIKKNKQKFF.GR.AG-K.DAEIRERVLEYFDKQK.TVDKLRGILTILEFQKIIVSSYTKILGVLTT.....
A0A097IVQ4_9POXV/1-108 .............MNIRIVEVLELYLGRKPSIAEYHTLKSQYKTIQKIILFNKDIFISLIKKNKKKFF.SN.IDTN.PSEIKASILKYFSKQE.RVFTIGKLYTIIELQTVLVTKYTDILGILTT.....
PAP1_YLDV/1-108 .............MSNSITLTLKNYLGRMPTINEYHMLKSQVRNIQKIMFFNKDIFISLIKKNKKKFF.SE.IKSS.PSEIKTHILEYFLKQQ.KTSSIGKLYTIIELQTILVSSYTDVLGVLTT.....
PAP1_HSPV/11-117 .........pnit-----LKIIETYLSRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFF.SD.VNTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
PAP1_DPV84/1-108 .............MNRHISEILEKYLGRIPSLTEYHTLKSQYKNIHRVNIFNKDIFISLIKKNKKKFF.SD.IDTS.VSEIKKLVFDYFTKQE.QTYSIGKLYTIIELQTILVTTYTDILGVLTT.....
PAP1_VAR67/11-117 .........pnit-----LKIIETYLGRLPSVNEYHMLKLQTRNIQKITVFNKDIFVSLVKKNKKRFF.SD.VDTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTNILGVLTI.....
PAP1_FOWPN/3-110 ...........rs--RQVYYIINEYLGRHPSSTEYQVLKHQVEKISKINNFNKETFFFLLKKNKNKFF.KD.LELS.DDLLKKRIDEYFSKQK.HAKRLGNLFAIMELQKILISSFTKTIGILTT.....
A0A1L3IZE3_9POXV/1-108 .............MNIRIVDVLELYLGRKPSLTEYHTLKSQYKTIQKINIFNKDIFISLIKKNKKKFF.SN.IDTN.PSEIKNSILKYFSKQE.RVFTIGKLYTIIELQTVLVTTYTDVLGVLTT.....
PAP1_CAMPS/10-117 ........lpnit-----LKIIETYLGRLPSVNEYYMLKLQTRNIQKITVFNKDIFVSLVKKNKKRFF.SD.VDTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
Q6TVV2_ORFSA/2-105 ...........ap------PVIEEYLGSRPSMERCVLLRAQRRNMSRVLNFDRKLFLSLVVKSRRRFF.KK.LGGS.EKEIAARIEEYFSRQR.RLEKLGQILTVLELQSVIVGEFTRTLGSLTT.....
A0A1B3B608_LSDV/1-109 ........mndki----VVDVLKLYLKRDPSLTEFHMLKSQYKNIQRVNIFNKEIFISLIKKNKKKFF.SD.IKSS.PSDIKRSILTYFSKQE.NTYSIGKLYTIIELQSILVTTYTDVLGILTT.....
PAP1_DPV83/1-108 .............MNRHISEILEKYLGRIPSLTEYHTLKSQYKNIHRVNIFNKDIFISLIKKNKKKFF.SD.IDTS.VSEIKKLVFDYFTKQE.QTYSIGKLYTIIELQTILVTTYTDILGVLTT.....
B2CWD4_9POXV/1-108 .............MNARIAELLHNYLGRPPSLSEYHMLKLQHRNIQKIIAFNKDIFISLIKKNKKKFF.SD.IDLT.SSEIKTSVLSYFSKQR.DTYSIGKLYTIIELQTILVSTYTDVLGVLTL.....
PAP1_MYXVL/1-108 .............MNARIAELLHNYLGRPPSLSEYHMLKLQHRNIQKIIAFNKDIFISLIKKNKKKFF.SD.IDLT.SSEIKTSVLSYFSKQR.DTYSIGKLYTIIELQTILVSTYTDVLGVLTL.....
A0A7H0DN36_MONPV/10-117 ........lpnit-----LKIIETYLGRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFF.FD.VDTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
A0A2U9QHI8_9POXV/1-108 .........mqpk-----KAIISAYIGKEPDISTYYILSAHSKNIYKIMRFDKMLFTSLLRKNKRRFFpHQ.TDAS.ASILAKRVNDYFNKQK.TISQVGRIVSIIELQYVLVTTYTHILGVLTM.....
Q1HTS9_9POXV/1-107 ........mssrt------NSVALYLDRTPDLETSTVLNSQLRSILRIMRFNKDLFISLVRKNKRRFF.KT.TEGS.HAKITERVNAYFSKQT.RETRIGNLLAIIEFQDLLVRTYTNTIGVLTT.....
PAP1_FOWPV/3-110 ...........rs--RQVYYIINEYLGRHPSSTEYQVLKHQVEKISKINNFNKETFFFLLKKNKNKFF.KD.LELS.DDLLKKRIDEYFSKQK.HAKRLGNLFAIMELQKILISSFTKTIGILTT.....
PAP1_VACCC/11-117 .........pnit-----LKIIETYLGRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFF.SD.VDTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
PAP1_SWPV1/1-108 .............MNRQIANILENYLGRYPSLNEYHTLKSQYRNIQKVNIFNKDIFISLLRKNKKKFF.SD.LVCT.QSDIKHSVLSYFSKQE.NTYSIGKLYTIIELQTILVTTYTDVLGVLTT.....
G3EIB3_9POXV/1-109 ........mttnl----TLNIISTYLDRKPSINEYHMLKSQVKNIQRIMAFNTDIFIALVKKNKKRFF.SD.IESS.PSDIKDRIINYFYKQQ.HTFIIRKIFTIIELQSVLVSTYTDVMGILTI.....
PAP1_CNPV/3-110 ...........rr--NQITSVIREYLGRNPVPKEYEVLKKQTLKLSKIINFNKDTFFFLIKKNKYTFF.KD.LNVS.DEEIQERIDEYFTKQR.RARRLGNLLAIVELQKLLVSSFTKTLGVLTT.....
PAP1_VACCW/10-117 ........lpnit-----LKIIETYLGRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFF.SD.VNTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
A0A1B1MRC6_9POXV/1-108 ..........mqs----TKQVITEYLGREPEISSYYLISAYYKNITKILKFNKTVFISLLRKNKRKFF.SHqTNAT.PTAISKRVSEYFSKQK.HTIQVGKILSIIELQTVLVTTYTQTLGVLTT.....
A0A0M3ZRP2_9POXV/3-110 ..........rks---QTYYIIRQYLGRPPSTTEYHMLKKQVDKISKVNSFNKDTFFFLLKKNKIKFF.KE.IDSN.DDILRKRIDDYFTRQQ.RCTKVGRLMAILELQKILVFTFTKTIGILTT.....
W6JLK0_9POXV/2-102 .niyirnkpldik----------------------NALVDYNDKINDIVKFDKNKFIKQLISIRDIYV.NDfIDTSkNDDISRRVNEYFDKQNvQNLKLGSIKSIIKFQHIIVTYVSKLL-----dniii
F1AWV9_ORFV/2-105 ...........ap------PVIEEYLGSRPSMERCVLLRAQRRNMTRVLNFDRKLFLSLVVKSRRRFF.KK.LGGS.EKEIAARIEEYFSRQR.RLEKLGQILTVLELQSVIVGEFTRTLGSLTT.....
A0A6B9R1Y0_9POXV/3-110 .............MNNNAKYILEKYLGRSITTSEYYMLKNQLYNINKILNFNKDIFISLLRKNKKRFF.SN.IDTN.YVDIKNRVINYFSKQH.NVYVIGHLLSIIEFQTIIVTTYTHVLGVLTI.....
A0A3F2YKI5_SHEVT/1-109 ........mndki----VVDVLKLYLKRDPSVTEFHMLKSQYKNIQRVNIFNKEIFISLIKKNKKKFF.SD.IESS.PSDIKRSILTYFSKQE.NTYSIGKLYTIIELQSILVTTYTDVLGILTT.....
Q9YVU9_MSEPV/2-97 ntyintrefdnel-------------------------IKYKQQIDTIVKFDKDEFIKKLIIIKDIYI.TDfINISkNNDIKRRVYTYFNKQN.TFDKIGSIIAVLKFQHLIVTYVNRL------ledi.
PAP1_MCV1/1-108 .............MNGAQFELLREYLGRPPTLNQYFIFKPQARAIQRIMRFDTDVFFALIKKNKKRFF.AR.IGGS.ASEINARVLSYFVKQR.ATTKVGRILSIIELQSVLVNSYTEIMGVLTL.....
A0A220T698_9POXV/3-110 .........ttni----IAITLENYLARQPTVNEYHMLKSQIKTIQRILKFNKDVFISLVKKNKKKFF.SD.IKTT.PSDIKNSILQYFTKQH.NVTSIGKLYTIIELQNLLVTTYTNILGVLTI.....
H6TA27_9POXV/1-108 .............MNIRIVEVLELYLGRKPSIAEYHTLKSQYKTIQKIILFNKDIFISLIKKNKKKFF.SN.IDTN.PSEIKASILKYFSKQE.RVFTIGKLYTIIELQTVLVTKYTDILGILTT.....
PAP1_YMTV5/1-108 .............MNNSITLTLKNYLGRMPTVNEYYMLKSQVRNIQKIMFFNKDIFISLIKKNKKKFF.YE.IKSS.PSEMRLHILEYFMKQQ.KTSSIGKLYAIIELQTILVSTYTDVLGVLTT.....
PAP1_RFVKA/1-108 .............MNARIADLLYNYLGRPPSLSEYHMLKLQHRNIQKIIAFNKDIFISLIKKNKKKFF.SD.IDLT.SSEIKTSVLSYFSKQR.DTYSIGKLYTIIELQTILVSTYTDVLGVLTL.....
A0A223FMP0_9POXV/3-110 .........ttnp----TLNIISKYLDRHPSINEYHMLKSQVRNIQRIMAFNTDIFIVLVKKNKKRFF.SD.IETS.SSEIKDRILSYFYKQQ.QTFIIGKLFTIIELQSVLVATYTDIMGILTI.....
Q0NPF3_9POXV/10-117 ........lpnit-----LKIIETYLGRLPSVNEYHMLKLQTRNIQKITVFNKDIFVSLVKKNKKRFF.SD.VDTS.ASEIKDRILSYFSKQT.QTYNIGKLFTIIELQSVLVTTYTDILGVLTI.....
A0A223FN92_9POXV/3-110 .........ttnp----TLNIISKYLDRHPSINEYHMLKSQVRNIQRIMAFNTDIFIVLVKKNKKRFF.SD.IETS.SSEIKDRILSYFYKQQ.QTFIIGKLFTIIELQSVLVATYTDIMGILTI.....
#=GC seq_cons ..................hpllcpYLGRhPSlsEYahLKtQh+NIpKIhhFNKDIFlSLlKKNKK+FF.o-.l-sS.sSEIKcRIlpYFoKQp.pshpIGKLaTIIELQolLVoTYTclLGVLTh.....
//
