#=GF ID   Q4D059-like
#=GF AC   PF21630.1
#=GF DE   Hypothetical protein Q4D059-like
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE   ECOD:EF20176
#=GF GA   27.00 27.00;
#=GF TC   109.90 109.80;
#=GF NC   25.20 17.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF RC   Paper describing PDB structure 2mni
#=GF RN   [1]
#=GF RM   25748338
#=GF RT   NMR structure and dynamics of Q4D059, a kinetoplastid-specific
#=GF RT   and conserved protein from Trypanosoma cruzi.
#=GF RA   Lopez-Castilla A, Pons T, Pires JR;
#=GF RL   J Struct Biol. 2015;190:11-20.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This protein family represents a group of proteins from related
#=GF CC   kinetoplastid parasites found in Trypanosomatidae, including the
#=GF CC   functionally uncharacterised Swiss:Q4D059 from Trypanosoma
#=GF CC   cruzi, which is predicted to be a 4-oxalocrotonate tautomerase.
#=GF CC   Q4D059 shows a parallel/ anti-parallel three-stranded beta-sheet
#=GF CC   packed against four helical regions [1].
#=GF SQ   9
#=GS A0A0N0DR71_LEPPY/5-84   AC A0A0N0DR71.1
#=GS Q38FZ4_TRYB2/6-85       AC Q38FZ4.1
#=GS A0A061IWA5_TRYRA/6-85   AC A0A061IWA5.1
#=GS S9TJ00_9TRYP/15-95      AC S9TJ00.1
#=GS A0A7G2CXB5_9TRYP/15-93  AC A0A7G2CXB5.1
#=GS A4I2H7_LEIIN/5-84       AC A4I2H7.1
#=GS Q4D059_TRYCC/6-85       AC Q4D059.1
#=GS Q4Q8T6_LEIMA/5-84       AC Q4Q8T6.1
#=GS Q4DAR1_TRYCC/6-85       AC Q4DAR1.1
A0A0N0DR71_LEPPY/5-84              l-TIELPYDRMVKEDCISDEYLINQMAGINDNPPEDNLPLRQWLIREAHLALVKNPKMKEVV.LKPKSDHSSRTEFAIKIT-g
Q38FZ4_TRYB2/6-85                  .IEIHIPLDRIRNEEYATDDLLLNCLSKIGDTPEEDGLPLRTWILREAHQALIKSPKLRTVL.VKPQTVKDKPTHFQICFDE.
A0A061IWA5_TRYRA/6-85              .VEVHLPLKRITADGYAKDDFLLNQLEKVNDTPEEDGMPLRAWVIKSTHDALEKNPKLREVH.LKPKAVKPCHTQFIVIIDE.
S9TJ00_9TRYP/15-95                 .VEVEIPRGRLIADAYASDDYLLNQLAGVNDTPEEEELPLRKWLLKQAHDTAIKQPKLEKVGpFKPKADKSSKMEFLFILTE.
A0A7G2CXB5_9TRYP/15-93             .IEVELPRDKITSEEWAEDVYLLNQLDGVNDTPEEEGLPLRKWLLLQVHESLKKDPKQTSVL.VKPKS-KHSKMEFEFKIQ-g
A4I2H7_LEIIN/5-84                  .VKVEIPRESIMKPSYMDDVYLLNQFDGVNDNPQEDGLPLRKWILREVHEVLAKNPRKTEVV.VKLKSDKSARTEFAVAII-g
Q4D059_TRYCC/6-85                  .VEIHFPLKRIAAEGYAEDELLLNQMGKVNDTPEEEGMPLRAWVIKCAHEALEKNPKIREVY.LKPRAVKNSSVQFHVIFDE.
Q4Q8T6_LEIMA/5-84                  .VKVEIPRESIMKPSYMDDIYLLNQLDGVNDNPQEDGLPLRKWILREVHEALAKNPRKTEVV.VKLKSDKSARSEFAVTII-g
Q4DAR1_TRYCC/6-85                  .IEIHFPLKRIAAEGYAEDELLFNQMGKVNDTPEEEGMPLRAWVIKCAHDALEKNPKIREVY.LKPRAVKNSSVQFHVIFDE.
#=GC seq_cons                      .lElclPhcRIhs-uYAcD-aLLNQhstVNDTPEE-GLPLRpWll+psH-ALtKNPKhcEVh.lKPKusKsu+scFtlhls..
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