#=GF ID RE_XamI
#=GF AC PF09572.14
#=GF DE XamI restriction endonuclease
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE Bateman A
#=GF GA 25.00 25.00;
#=GF TC 44.50 44.30;
#=GF NC 24.10 21.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF CL CL0236
#=GF RN [1]
#=GF RM 415144
#=GF RT A new restriction endonuclease from Streptomyces albus G.
#=GF RA Arrand JR, Myers PA, Roberts RJ;
#=GF RL J Mol Biol. 1978;118:127-135.
#=GF RN [2]
#=GF RM 22638584
#=GF RT Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT phosphodiesterase superfamily.
#=GF RA Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA K;
#=GF RL Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR INTERPRO; IPR019072;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family includes the XamI (recognises GTCGAC but cleavage
#=GF CC site unknown) restriction endonuclease.
#=GF SQ 86
#=GS A0A512E2R7_9PROT/60-317 AC A0A512E2R7.1
#=GS A0A0U3N7K1_9BURK/119-346 AC A0A0U3N7K1.1
#=GS A0A1G6SKE9_9BURK/54-290 AC A0A1G6SKE9.1
#=GS A0A1H1NVV3_9BACT/62-294 AC A0A1H1NVV3.1
#=GS E4NPA7_HALBP/50-272 AC E4NPA7.1
#=GS A0A7L5YNM6_9CHLR/53-312 AC A0A7L5YNM6.1
#=GS A0A5C5W567_9BACT/56-307 AC A0A5C5W567.1
#=GS A0A7W8M8Q4_9BURK/53-308 AC A0A7W8M8Q4.1
#=GS A0A7W9Q8D0_9ACTN/52-303 AC A0A7W9Q8D0.1
#=GS A0A161S953_9NEIS/54-290 AC A0A161S953.1
#=GS E5AMB6_MYCRK/54-290 AC E5AMB6.1
#=GS A0A6J4FP02_9PROT/52-287 AC A0A6J4FP02.1
#=GS A0A1E2RYQ1_9HYPH/5-198 AC A0A1E2RYQ1.1
#=GS A0A848HKJ5_9BURK/58-292 AC A0A848HKJ5.1
#=GS A0A6G2HIK6_9EURY/43-280 AC A0A6G2HIK6.1
#=GS A0A3A3YN38_9ACTN/61-300 AC A0A3A3YN38.1
#=GS A0A087APA1_9BIFI/1-213 AC A0A087APA1.1
#=GS I0V635_9PSEU/53-307 AC I0V635.1
#=GS A0A139WQC3_9CYAN/53-308 AC A0A139WQC3.1
#=GS A0A1J1LUQ6_9CYAN/62-317 AC A0A1J1LUQ6.1
#=GS A0A8J6RG24_9CYAN/53-308 AC A0A8J6RG24.1
#=GS D2UFF2_XANAP/54-290 AC D2UFF2.1
#=GS A0A1V1NUQ3_9DELT/1-96 AC A0A1V1NUQ3.1
#=GS A0A172UA23_9GAMM/54-290 AC A0A172UA23.1
#=GS A0A8J7X1V6_9GAMM/53-309 AC A0A8J7X1V6.1
#=GS A0A6G2HJ91_9EURY/51-287 AC A0A6G2HJ91.1
#=GS A0A285NT01_NATPI/51-289 AC A0A285NT01.1
#=GS A0A6N6NJ51_9ACTN/73-292 AC A0A6N6NJ51.1
#=GS A0A2N3XWF9_SACSN/56-291 AC A0A2N3XWF9.1
#=GS B4VV75_9CYAN/1-208 AC B4VV75.1
#=GS A0A1M7GGS4_9PROT/53-308 AC A0A1M7GGS4.1
#=GS A0A3S0D0Z5_9ACTO/56-288 AC A0A3S0D0Z5.1
#=GS I4EKI5_9CHLR/52-303 AC I4EKI5.1
#=GS W9GM81_9MICO/55-288 AC W9GM81.1
#=GS G5F5M4_9ACTN/1-208 AC G5F5M4.1
#=GS W8X8B5_CASDE/1-199 AC W8X8B5.1
#=GS W5TLJ5_9NOCA/56-291 AC W5TLJ5.1
#=GS A0A8J7DR36_9CYAN/53-307 AC A0A8J7DR36.1
#=GS A0A6M8IWJ0_9ACTN/55-312 AC A0A6M8IWJ0.1
#=GS A0A0W8I8Y6_9MICO/56-289 AC A0A0W8I8Y6.1
#=GS A0A179B407_9ACTO/59-290 AC A0A179B407.1
#=GS A0A2V1H7F9_9GAMM/53-304 AC A0A2V1H7F9.1
#=GS K9W514_9CYAN/53-308 AC K9W514.1
#=GS A0A1W6Z3X0_9BORD/54-290 AC A0A1W6Z3X0.1
#=GS A0A2U1VTB4_9PROT/68-298 AC A0A2U1VTB4.1
#=GS A0A1R4HQQ6_9MICO/56-290 AC A0A1R4HQQ6.1
#=GS D6CQ51_THIA3/53-308 AC D6CQ51.1
#=GS A0A0D5LT20_MAREN/61-291 AC A0A0D5LT20.1
#=GS A0A1C3EE48_9GAMM/53-307 AC A0A1C3EE48.1
#=GS A0A2U2MYL1_9GAMM/56-289 AC A0A2U2MYL1.1
#=GS A0A4R5ZX96_9RHOB/53-308 AC A0A4R5ZX96.1
#=GS A0A285NS44_NATPI/50-287 AC A0A285NS44.1
#=GS D8FT64_9CYAN/53-308 AC D8FT64.1
#=GS A0A1M5Y8L3_9RHOB/53-307 AC A0A1M5Y8L3.1
#=GS A0A849HLF1_9MICO/27-261 AC A0A849HLF1.1
#=GS A0A074JVI7_9RHOB/53-307 AC A0A074JVI7.1
#=GS L7LQC5_9ACTN/56-290 AC L7LQC5.1
#=GS K9U9Q7_CHRTP/53-309 AC K9U9Q7.1
#=GS A0A5N5RLD6_9BIFI/60-312 AC A0A5N5RLD6.1
#=GS A0A3S2YR16_9HYPH/50-285 AC A0A3S2YR16.1
#=GS A0A3S8UD23_9RHOB/54-288 AC A0A3S8UD23.1
#=GS A0A1H1DJE6_9GAMM/31-258 AC A0A1H1DJE6.1
#=GS A0A6F8YIF9_9ACTN/58-285 AC A0A6F8YIF9.1
#=GS A0A2H6BA92_9HYPH/54-281 AC A0A2H6BA92.1
#=GS A0A4V1A3G0_9BACL/27-282 AC A0A4V1A3G0.1
#=GS A0A2U2MXE6_9GAMM/55-288 AC A0A2U2MXE6.1
#=GS J1GS95_9ACTO/55-288 AC J1GS95.1
#=GS A0A073CCG9_PLAAG/62-317 AC A0A073CCG9.1
#=GS A0A0T1WGM3_9MYCO/58-285 AC A0A0T1WGM3.1
#=GS A0A2M9HNM3_9BIFI/59-293 AC A0A2M9HNM3.1
#=GS A0A563ADK4_9BACT/53-307 AC A0A563ADK4.1
#=GS A0A378TF56_9MYCO/17-244 AC A0A378TF56.1
#=GS A0A844MGF6_9CYAN/53-308 AC A0A844MGF6.1
#=GS A1BGJ7_CHLPD/15-270 AC A1BGJ7.1
#=GS A0A437J996_9SPHN/52-286 AC A0A437J996.1
#=GS K9T9V4_9CYAN/53-309 AC K9T9V4.1
#=GS U5QC54_9CYAN/53-306 AC U5QC54.1
#=GS A0A7L5ZLJ8_9BACL/50-285 AC A0A7L5ZLJ8.1
#=GS A0A2V3JHF6_9EURY/52-304 AC A0A2V3JHF6.1
#=GS A0A1H1YE88_9ACTN/52-236 AC A0A1H1YE88.1
#=GS A3X310_9BRAD/1-65 AC A3X310.1
#=GS U1YI14_9BURK/53-311 AC U1YI14.1
#=GS A0A1I1YKD5_9BACL/52-319 AC A0A1I1YKD5.1
#=GS A0A0P4UKT0_9CYAN/53-309 AC A0A0P4UKT0.1
#=GS A5USP4_ROSS1/56-179 AC A5USP4.1
#=GS A0A087EKU8_9BIFI/52-304 AC A0A087EKU8.1
A0A512E2R7_9PROT/60-317 .....................................ENLT..NI...KPD.LL..KM..HPGALQ.TLRMSTCPPLAVDRLIGLAGVSKNLVGCME-.IG....EIPRRM..PLAELERDLSKIGAIIEKMADPDIFVWLGRA.....TDA.....TETEVHRAATIVADRLCG.A.V.A.NP.IIR.NAQEKR......QLA.LISAWL.EAR.EpkYTRLPEGI--.R.FD..A.M....PPGTYS.FRLNVPVK........qEGGTK....nVNIPVDAVVMPHTAQNGDLPLLIEAKSAGDFTNTNKRRKEEATKVQ.QLRST.YnrdGK..YIRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A0U3N7K1_9BURK/119-346 ...............................ellasi----..--...---.--..VS..HKLQFQ.ALRALAAPPISEDDLDTLLD------ARVN-.--....KTAVRR..NSALAD----EIGRLLLAALDPHRFPWVLQG.....RPP.....TEVERY-TAIMATAVLIS.M.N.T.VY.TRR.RSDERD......QLEgRLEQLL.VDK.G..YTRAPAPRGG.I.AD..VgM....LPPRGV.FMRQCKL-.........--GKH.....---NADLVVMLWDGR----LLAVECKASNSTVNGEKRLNKEVVADA.GDWYDqF...GR..SNLV.AAALRGVF.KPAKVREAQ....E.QGVYLFW..............
A0A1G6SKE9_9BURK/54-290 ..................................snl---NprSI...TDN.KL.aEA..YGLGLGeALRYLAGPPISDDDLQVIAD-----VDSIA-.PG....VLKKDP..EA------LRKVFQVIERVIDPHRFPWIEAG.....TAP.....SAQQRE-AALLASSVLLA.A.-.-.--.-QR.IATERRnegkqnQET.KVKNYL.RGL.G..FTEVPTMM--.-.IN..T.Iv..kGPQAMQ.FCAECQL-.........--GER.....---KADVVVRLHDTR----LMAIECKVSNSSTNSVKRLNNDAAVKA.EYWITqF...GR..AQVVpAAVVAGVF.KVLNLEQAQ....D.RGLSLFW..............
A0A1H1NVV3_9BACT/62-294 ............................pvnqsalae----..--...---.-V..MR..NRDLLT.ALRYVGAPPVSEDDLETLSG------DSLN-.AT....RILSDA..EF------ATAVKDVLCAILDPKRFPWIAAR.....REP.....TKQERS-AAILASTVLAS.S.-.Q.EV.QTK.RRSDERq....iVEG.LVEGVL.IGL.G..YKKRAAPQKG.-.IQ..S.LlgadVPKPGE.YMTGCTL-.........--GEN.....---NADFVIGLWDSR----LLVIEAKGSNSAINSRKRLNMEAVQKA.KAWAT.F...GR..DVIS.AAAIRGVF.NPAGVVSAQ....E.TPLVIFW..............
E4NPA7_HALBP/50-272 ....................................n-NFR..DI...EKE.DI..RE..DPRIVR.ILRYLVKPKISQMKFGQFAGVNS--TNNYE-.EY....TLAEAS..TP--NHQIAQDLADFTAANLDPEKVPWLSDP.....TID.....EEEEIEYSRRWICDKIAE.Q.E.A.TT.HYR.NWRKDK......QEQ.TVAEML.DDA.G..YTDSGYSGKIsS.TN..D.I....PVGT--.YAEESKV-.........-AGAD.....V-QKADFIVRPTEDT----VIFIEAKAIGVRVDSHKRVKEIRNKAS.DWKDE.F...EG..AETV.--------.---------....-.-------aviegwt.......
A0A7L5YNM6_9CHLR/53-312 ...................................df--LR..DI...SVE.RL..RA..NPGILP.ILRMACAPPLARDRLIGLAHLNRGLVSSMEG.ASgsapRIPPRM.pAVEQXSEQLQRMCDTIIELADRDLFIWLDGG.....DEP.....AKEQYIRAAMVVADRLCG.A.A.A.DP.IIR.NAQERR......QLE.TIGAWL.SRR.G..YANVSPASVE.D.VL..Q.M....PPGTFS.FRMNVRVG.........ESRAA.....VNLPVDCVIQPHHAQPGDIPVLIEAKSAGDATNTNKRRKEEAQKYH.QLVSR.F...GP..AVKY.VLFLCGYFxEPGYLGYEA....S.EGIDWIW..............
A0A5C5W567_9BACT/56-307 ....................................r-DLR..AI...DAA.TL..RA..NPAALP.TLRMCTAPPLAVDRLIGLAKVRRSLVGRLE-.AG....KLPTRT..SGGALESELEKLCKVLSQLLDRDIFPWLAVR.....DAP.....TARDWDRAATIVADRLCG.A.T.A.NP.IIR.NAQEQR......QLE.LIGRWL.RSR.G..YRLKPHPPRM.A.IT..D.M....EPGTYS.IRTNLIV-.........GTTVK.....VNIPIDVVVQPKKLLADRLPILLECKSAGDFTNTNKRRKEEAAKVH.QLRAT.F...GG..SVCF.VLVLCGYF.GADYLGYEA....A.EGIDWVW..............
A0A7W8M8Q4_9BURK/53-308 ....................................g-NLT..NI...KPA.LL..RE..HPEILP.TLRMSTCPPIAVDRLIGLAGVSATLVKSMEQ.DK....RLPVRM..SACEADTHLVKIGEIIEKMADPDIFVWIGRQ.....QPA.....NQAEIHRAATIVADRLCG.A.V.A.NP.IIR.NAQEKR......QLA.AIKAWL.EAR.G..YTQQPGGDGV.K.FD..A.M....KPGTFS.FRMNVPVK........lEGGVQ....eVNIPVDAVIKPKKAKAGELPIFFEAKSAGDFTNTNKRRKEEAVKMA.QLRSN.Y...GA..NVRF.NLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A7W9Q8D0_9ACTN/52-303 ....................................r-DMT..DI...SPE.AL..LR..SPQALR.TLRMCTSPPLARDRLAGLSYGSKILVGIME-.QG....KLPQRM..MAAELEAQLSRMCDVVTELLDLDLFDWCSTG.....GPA.....SSRQRELATTVVADRLSG.A.I.A.EP.IIR.NAQERR......QLT.LIGEWL.TVR.G..YKQKAHRAAA.P.LE..T.M....EAGTFS.FRQIVVV-.........--GDSl...sVNIPVDVVIQPLSPAPHRLPILVEAKSAGDFTNPNKRRKEEATKIN.QLQGK.Y...GP..NISL.LLFLCGYF.NAGYLGYSA....A.EHLDWVW..............
A0A161S953_9NEIS/54-290 ...................................sd--LNpgAI...TDD.NL.aEA..YGLGLGeALRYLAGPPISDDDLQVIAD-----VDSIA-.PG....VLKRNP..EA------LRKVFGVIERVIDPHRFPWMETG.....NLP.....TDQQRE-AALLASSVLLA.A.-.-.--.-QR.IATERRnegkenQET.KVKDFL.RSL.G..FTEVPAVA--.-.IN..T.Iv..kGPQAMQ.FCAECQL-.........--GER.....---KADVVVRLHDTR----LMAIECKVSNSATNSVKRLNNDAAVKA.EYWIKqF...GT..AQVVpAAALAGVF.KVLNLEQAQ....A.RGLSLFW..............
E5AMB6_MYCRK/54-290 ...................................sd--LNpgAI...TDD.NL.aEA..YNLGLGeALRYLAGPPISDDDLQVIAD-----VDSIA-.PG....VLKKNP..EA------LRKVFKVIERVIDLHRFPWIEAG.....GAP.....TEQQRE-AALLASSVLLA.A.-.-.--.-QR.IATERRnegkenQET.KVKDYL.RSL.G..FTEAPAVA--.-.IN..T.Iv..kGPQAMQ.FCAECQL-.........--GER.....---KADVVVRLHDTR----LMAIECKVSNSATNSVKRLNNDAAVKA.EYWIKqF...GI..AQVVpAAALAGVF.KVLNLEQAQ....A.RGLSLFW..............
A0A6J4FP02_9PROT/52-287 ........................nylstiavalmes----..--...---.--..--..-GGHML.ALRHFLAPPISQDQFKLLCP---TWPKTSE-.KS....GSPVGA..------GPAVAVAEMFAQWRDRHLTRWLDAG.....RKP.....TRVELR-EVLLALSPLIA.A.Q.T.FAtTRR.NRLAAK......QEQ.AVIELL.EAK.G..WTRRPSRLID.R.-R..A.A....VPE-KH.FMHKTRFA.........TATTT.....-PQEVDVACGLRDTL----VLAMECKVTNDETNSVKRV-NDVLKKA.EAWKThW...GS..FVVT.AALLEGVI.AAKDVERLI....D.AKVHVFW..............
A0A1E2RYQ1_9HYPH/5-198 ......................apslsrarlekspdl----..--...---.--..--..------.-------------------------------.--....------..--------VQRTVAVVRQVIDRRRFAWVVEG.....REP.....TEAERD-AAVMASAALMA.A.-.-.--.-SR.TQTRRRtsgktkQEA.TVKAAL.EEL.G..FAEVASRE-I.Q.NV..S.Y....APEPGE.FCGESVL-.........--GNR.....---KADIVVRLWDHR----IMPIECKVSNSSTNSVKRLNNDAAVKA.VTWRTdF...GR..RQVVpSAVLSGVY.KLHNLIDAQ....E.RGLSIFW..............
A0A848HKJ5_9BURK/58-292 ................................lidvp----..--...--A.AL..VE..SGEHML.VFRHITAPPISQDQFSLVC---PGWRKATE-.--....--RPHG..SRIKLD-EAQFIAAAFEERRSRPLTPWVDAE.....RRP.....LKREVRRLLWTIAPLIAS.Q.Q.I.QT.IQR.TRAASA......QER.AITTML.ANK.G..WMREPSSL-L.D.TR..A.A....LP-ARH.FMHKTRYA.........TATSS.....-PQEVDIALGLNSTV----VLAMECKVSNDQTNSVKRVN-DVLKKS.NAWKThW...GS..FVKT.AALLQGVI.APKDVARLI....D.DGVEVFW..............
A0A6G2HIK6_9EURY/43-280 ....................................d-NFR..DV...DVE.FV..RE..NPLTVR.ILRYLTEPILSRDKFSEYCDVGDQTLGKYED.--....---YED..DTTPRTETAEKIIDTFEEYRNESLLPWLEIGglgyhEYD.....ENALIKKLQTAIAYNIAT.S.E.A.NT.EYR.NWRATK......QHD.AIAGEL.VEA.G..FEKVEVDG--.-.VE..D.L....EPGEYE.TELNVSN-.........-----.....--EEADFAIRNYSGV----LTLIEAKMSGTEINFRKRRKEMV-NDY.NDWTE.D...RS..DARI.VAVIGGVI.NTNDVETLQ....E.TGIRVFW..............
A0A3A3YN38_9ACTN/61-300 ....................................d-DLR..EL...TGK.VF..RD..DPGAWQ.VFRYVCGPPISQEDLWTLVG-----GPRF--.-K....RVPPQY..AD--------ATAAALRLVVDNVRFPWVADG.....RAP.....TEHERR-AAVLATTVLHA.A.Q.M.LG.TSRrGEASLR......QED.ATAAAL.AAA.G..YQLEPSRRTL.RvLD..E.L....PRGTYS.RERKIAAG.........PGGAE.....KPAKCDVPVRLLDGR----LFAVECKVSNGPKNSWKRVNREVGGKA.ETWRQaF...GS..QVLT.AVVLAGVF.DLSCLVTAQgsspA.NGVVLLW..............
A0A087APA1_9BIFI/1-213 mrntdrptvseddfknlsgagtssasrfrdgelaeaa----..--...---.--..--..------.-------------------------------.--....------..------------LDYLARNINTDVFPWVASG.....MEP.....TDEQRH-AACVAIAALVA.DqK.T.KT.YMR.GGSSKA......QEN.IVRETL.VSEcG..MSPVEGHD-F.R.LS..A.D....GPARGQvFERETKV-.........-AGTK.....----ADIVLGLFDGR----IMCLECKVSNSEVNSFKRLNHEAVDKVfKWRAA.F...GE..QCVS.GAVLQDCF.KTANLVSAQ....D.AGAFLFW..............
I0V635_9PSEU/53-307 ....................................t-EMR..SI...TPD.VI..RK..RPEIVA.TLRMATAPPIARDRLTGLASLPNGFVKKLE-.SG....NLPGRM..SVADLDKHLESICSVIDELLDRGLFDWLDGN.....RAP.....DPQQRELAAVVVSDRRCG.A.V.A.DP.IVR.NAQEAR......QLG.VIEDWL.VAR.G..YTKRQHPGSQ.S.LE..S.M....PRGTFS.FRQNVPVR........sEDGQR....tINMPIDAVIQPHTPFPNGFPLLIEAKSAGDFTNTNKRRKEEATKIR.QLRST.Y...GN..DIRL.VLFLCGYF.DAGYLGYEA....S.EGLDWVW..............
A0A139WQC3_9CYAN/53-308 ....................................a-NLT..NI...TPT.VL..RQ..HPSILP.ILRMATAPPLARDRLIGLAGVLPNLVKNMEE.KS....RIPPRM..DSGLVDAELMKIGQIITRLADKDIFPWLENE.....LEP.....TETQVHRAATIVADRLCG.A.L.T.DP.IVR.NAQERR......QLA.LIRQWL.EQR.G..YSYVRGGASL.S.FE..T.I....QPGNFS.FRLNVPVS........lQSGSK....qVNIPIDVVIMPLQSNPGDLPLLIEAKSAGDYTNPNKRRKEEAIKIA.QLWLN.Y...GN..NVRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A1J1LUQ6_9CYAN/62-317 .....................................ENLT..NI...TPA.IL..QQ..YPSVLP.ILRMATAPPIARDRLIGLAGVSSNLVKNMEE.KQ....RIPPRI..DRETLDNELRKIGKIIARLADKDIFSWLNTE.....RQP.....TDTEVNRAAIIVADRLCG.T.I.S.DP.IIR.NAQERR......QLA.TIRQWL.EQR.G..YSYIGGGTRL.S.FE..R.M....QPGTFS.FRLNIPIL........lQGGTK....qINIPIDIVIQPIQSSPSQLPLLIEAKSAGDYTNPNKRRKEEAVKMA.QLRNN.Y...GN..NVRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A8J6RG24_9CYAN/53-308 ....................................a-NLT..NI...TPA.VL..RQ..HPEVLP.ILRMATAPPIARDRLIGLAGVSPNLVKNMEE.KQ....RISPRM..SSTLVDAELQKISQIIARLTDKDIFPWLENG.....LEP.....TDTQVHRAATIVADRLCG.A.L.A.DP.IVR.NAQERR......QLA.TIRQWL.EQR.G..YSYIRGGAGL.S.FQ..T.M....QPGTFS.FRLNIPVS........lQGGIK....qVNIPIDTVIKPLQSSPSDLPLLIEAKSAGDYTNPNKRRKEEAIKVA.QLRLN.Y...GN..NIRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
D2UFF2_XANAP/54-290 ...................................sd--LNpgAI...TDD.NL.aEA..YGLGLGeALRYLAGPPISDDDLQVIAD-----VESIA-.PG....VLKKNS..EA------LRKVFEVIERVIDPHRFPWMEAG.....GAP.....TDQQRE-AALLASSVLLA.A.-.-.--.-QR.IATERRnegkqnQET.TVKDYL.RSL.G..FTEAPAVA--.-.IN..T.Iv..kGPQAMQ.FCAECQL-.........--GER.....---KADVVVRLHDTR----LMAIECKVSNSATNSVKRLNNDAAVKA.EYWIKqF...GT..AQVVpAAALAGVF.KVLNLEQAQ....T.RGLSLFW..............
A0A1V1NUQ3_9DELT/1-96 ...................................mi----..--...---.--..--..------.-------------------------------.--....------..-------------------------------.....---.....------------------.-.-.-.--.---.------......---.------.---.-..----------.-.--..-.-....------.----VPAN.........QKGKKk...qVNIPVDAVIKPKNSVPEDYPILFEAKSAGDFTNTNKRRKEEAVKMM.QLMST.Y...GE..NIKF.VLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A172UA23_9GAMM/54-290 ................................gnldp---S..AI...TDA.NL.aDA..YHLGLGeALRYLAGPPISDDDLRVIAD-----VDSLA-.PG....VLRKDP..DA------LRKVFDVISRVIDPHRFPWIKAN.....RTP.....NDQERE-AALLASAVLLA.A.-.-.--.-QR.IATERRnegkdnQET.KVKDYL.RGL.G..FVEVPPVA--.-.IN..T.Iv..kGPQAMQ.FCAECLL-.........--GER.....---KADVVVRLHDTR----LMAIECKVSNSATNSVKRLNNDAAVKA.EYWIKqF...GI..AQVVpSAVLAGVF.KVLNLEQAQ....E.RGLSLFW..............
A0A8J7X1V6_9GAMM/53-309 ....................................d-NLA..NI...QPA.MM..RQ..HPEILP.TLRMSTCPPLAVDRLIGLAGVSSTLVKCMEI.EK....KLPARM..TQAATDKELARIAAIIEKMADPDIFVWLSRK.....SQP....aTEPEIHRAATIVADRLCG.A.V.A.NP.IIR.NAQEQR......QLA.AIKNWL.EAR.G..YKQLMTGDGV.K.FD..A.M....PPGTFS.FRMNVPVK........lEGGAK....sVNIPIDAAINPRTAKKSGFPVFFEAKSAGDFANTNKRRKEEAMKMT.QLRST.Y...GK..KVQF.NLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A6G2HJ91_9EURY/51-287 ....................................n-NFR..DF...SSE.VI..RE..EPNVVK.LLRYLVKPPISQMKFGQFAGITS--TDSYEK.ES....PTTPQH..------DTAEQMADFVERNLDERKVPWLNED.....VD-.....EEYEVEQSREWVCDIIAQ.S.E.A.KT.RYR.NWRKDV......QEE.KVAETM.LKA.G..LEKVNISLLE.S.ED..D.I....PTGSFT.PETKVSV-.........TGGDH.....--QKADFVARERDGG----LVFIEAKAIGVKIDSYKRIKEIRNKES.DWRRT.H...PD..S-TV.AAALSGWI.PESQIETLL....N.DDITVFW..............
A0A285NT01_NATPI/51-289 ....................................n-NFR..NF...GPS.VI..RD..NPNVVK.VLRYLVKPPISQMKFGQMSG--INSTDSYEK.DN....PTTPNT..NT------AEQMADFVERNLDERKVPWLHEN.....VQD.....EDYELEQSREWVCDIIAQ.S.E.A.KT.RYR.NWRKDV......QEE.KVAETM.MEA.G..LEKVSRSSVL.E.SK..D.D....IP-TGS.FVPETKVA.........VSGGD.....-NQKADFVARKRDGG----LVFIEAKAIGVKIDSYKRIKEIRNKES.DWRST.Y...PD..A-DV.GAALSGWI.PESQIDTLV....N.DNITIFW..............
A0A6N6NJ51_9ACTN/73-292 ................................lisgy----..--...---.--..--..----LQ.TLRNMCRPTVSEDDFKNLSD-----TGTVS-.AS....KFSDIG..LS-------QSALGYLERNLNRDIFSWLDAD.....TAP.....TDSERHAAAVAVAALAAE.Q.K.T.KT.LMR.GSSSKR......QEQ.AVREAL.IARcG..LKSVASKS--.-.FE..L.Ls..nGPGKGElFDRETLV-.........-AGTK.....----ADVVLGLYDGR----IMCLECKVSNSEVNSFKRLNHEAVDKV.KKWAGsF...GK..QCVS.GVVIQGCF.KAANLVSAQ....D.DGA----ylf...........
A0A2N3XWF9_SACSN/56-291 ...................................id--LS..EL...REQ.AA..EQlsDPRVLY.SVRYLAGPPISTDDLKELVG--DGV--SLA-.PT....KIKSDP..EM------ARRVVETVLLGLDRVRFPWVGED.....REP.....TDAERE-IAVIATAAMIA.T.-.-.--.-QR.VQTARRneakdeQED.AVAEVL.KQN.G..FIEVPTRV-V.E.NT..S.H....FPGPGE.FCRESEF-.........--GGR.....---KADLIVGLWDGR----VMPIECKVSNSSTNSVKRLNNDAAAKA.ETWIKvF...GT..ATVVsTAVLSGVF.KIHNLESAQ....S.RGLTLFW..............
B4VV75_9CYAN/1-208 .....................................----..--...---.--..--..------.----------------------------MEK.EK....KLPIRL..QGNALDIELRKIGKIIERMADPDIFTWLNRS.....ESP.....SQTDIYRAATIVADRLCG.S.V.T.NP.IIR.NAQERR......QLA.AIQNWL.ETR.Q..YRKLVGQDGV.K.FD..Q.M....PPGTFC.FRMNVPIN........lETGKV.....INIPVDVAIKPKSSSMDELPVFLEAKSAGDFTNVNKRRKEEAIKMS.QLRST.Y...GD..QVQF.NLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A1M7GGS4_9PROT/53-308 ....................................g-NLT..DI...KPA.LL..RK..YPEILP.TLRMSTCPPIAVDRLIGLARVSPTFVKSMEL.YK....RLPMRM..SVADADAQLAKVADIIERMADPDIFVWIGRG.....TPA.....TEVEIHRAATIVADRLCG.A.V.A.NP.IIR.NAQEKR......QLA.GIKAWL.EAK.G..YRQLLGGEGI.K.FN..A.M....QPGTFS.FRMNVPVK........lEGGIQ....sVNIPVDAVIMPITGLVGELPIFLEAKSAGDFTNTNKRRKEEAVKMS.QLRST.Y...GP..GVRF.NLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A3S0D0Z5_9ACTO/56-288 .................................dlqe--LT..GV...VQE.YI..ID..QDKR-Y.ALRYLASPPVSDDDLKVLAD------AKFS-.PA....ALEKDP..DA------VARIIEVVLAGLDRWRFPWLTEG.....REA.....TEMERR-IATISTTSLIA.T.S.RlQT.YRR.NTQKTD......QEE.HIADAL.RSI.G..FQGVPTRNIG.-.-S..V.L...dAPAPGE.FCHESLL-.........-GGSK.....----ADIIARLWDGR----ILAIEAKVTNSATNSVKRVNREAATKA.VNWLNkF...GT..LGVIpCAVLSGVF.KVHNLVSAQ....N.DGLTIFW..............
I4EKI5_9CHLR/52-303 .....................................NDLE..SI...APE.TL..LV..SPQVLP.ILRMCTAPPLARDRLVGLSNTTKNLVGNLE-.AG....RLPPRM..PKDQLQAALTKISETILRLLDVDLFPWLSEH.....SLP.....SEQMRDRSAMVVADRLTG.A.N.A.DP.LIR.NAQEQR......QLD.KLRQFL.VER.G..YKEEQPPPGS.L.PT..A.M....PRGTFW.FRLNVRV-.........--GAEl...eVNIPIDAVIQPKGAPLGAMPILIEAKSAGDFTNVNKRRKEEATKNR.QLQER.Y...GD..QTKI.ILLLAGYF.DAPYLGYEA....A.EGLDWVW..............
W9GM81_9MICO/55-288 .................vdlsrlhedaagrlgdraqq----..--...---.--..--..-----E.VVRYLAGPPISADDLKVIAD------ARLS-.AT....ALTADE..QM------ARRVIDTVLLGLDRERFPWVGED.....REP.....TETERA-AAITSTAALIA.A.-.R.RV.LTA.RANEAKg....eQEE.KVKAAL.RAE.G..FTEAAPRTI-.-.-A..T.Lh..dAPGAGE.FCGESLF-.........--GTR.....---KADIIIRLWDHR----VMALECKVSNSSTNSVKRLNNDAAVKA.GIWIDeF...GR..AQTVpAAMLAGVF.KRHNLEQAQ....D.RGLTLWW..............
G5F5M4_9ACTN/1-208 ....................................m----..--...---.--..--..------.-----------------------------E-.EG....RLPTRN..RQRFIDEQIPALLGVIDRLLDRQLINWLGYE.....HDP.....LSMDMYVAKSVVADRLCG.T.T.S.DP.IIR.NAQEAR......QLA.VIAAYL.EPK.G..YTLIDDAS-V.G.PF..E.M....PRGTFA.YHKNVRMYqn.....arD-DSNg...yVNTPVDVVIMPMDPS-IDTPLLVECKSAGDFANTNKRRKEEDTKVT.QLRST.Y...GD..-VTL.YLFLCGYF.DSTYLGYEA....A.NHMDWVW..............
W8X8B5_CASDE/1-199 ....................................m----..--...---.--..--..------.-------------------------------.--....------..SSVKADQELEKIAAVIERLADPDIFVWLNRA.....ASA.....TKAEIHRAATIIADRLCG.A.V.T.NP.IIR.NAQEQR......QLA.VIQAYL.EQR.G..YRRLHPGDGI.K.FN..S.M....PSGTFS.FRMNVPIK........qTNGVQ....sINIPIDAVIMPKAAKRGDLPLFFEAKSAGDFTNTNKRRKEEAVKMA.QLRHT.Y...GP..NVRF.NLFLCGYF.DSGYLGYEA....A.EGIDWAW..............
W5TLJ5_9NOCA/56-291 ..................................vdl---S..QLadqASD.LL..TQ..SEDTLT.TIRYLASPPISADDLKELAE------TTLS-.RS....RLIAEG..GV-----AARRVIETVLLGLDRNRFPWIGED.....REP.....TDAERN-AAVISTAALIA.T.-.-.--.-QK.VQTARRneakdeQES.LAASYL.VSQ.G..FRQVPTRKIV.-.-S..V.M...dMPQPGE.FCRESMF-.........--GDR.....---KADLVVRVWDGR----IMPIECKVSNSSTNSVKRLNNDAAVKA.KAWIEqF...GN..RTTIpAALLSGVF.KVHNLESAQ....T.AGLTIIW..............
A0A8J7DR36_9CYAN/53-307 .....................................NNLT..NV...APA.IL..RK..HPGVLP.TLRMSTCPPLAVDRLIGLAAIPSSLVKRMEN.KK....KLPVRL..RGAALDIELQKIGDIIERMADPDIFTWLNRT.....EPP.....LQAEIRRAATIVADRLCG.S.V.A.NP.IIR.NAQEKR......QLA.AIQSWL.ETF.Q..YRKLTVQDGM.K.FS..D.M....PPGTFS.FRMNIPVT........lETGKI.....INIPIDAVIKPKSSQRREMPILFEAKSAGDFTNVNKRRKEEAIKMS.QLRRT.Y...GN..QVRF.SLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A6M8IWJ0_9ACTN/55-312 ....................................d-DLK..SI...NPA.LL..LK..NPALMT.TLRMLCAPPIARDRLAGLAGVSSSRVKNME-.EG....KLPVRKrdQEAFVGRELPSMLSVINRLLDRELMPWLDNG.....DNP.....EDTNLLVAKSVVADRLCG.S.T.S.DP.IIR.NAQETR......QLK.VIADYL.DAK.G..YSYLEYSS-V.D.AF..N.M....PHGTYA.YHKNVSMFk......naRDASDg...mVNTPIDVVIMPLDKY-ATRPMLVECKSAGDFANTNKRRKEEDTKVT.QLRAT.Y...GD..DIVL.YLFLCGYF.DSTYLGYEA....A.NHMDWIW..............
A0A0W8I8Y6_9MICO/56-289 ....................................v-DLS..RL...SDE.AVeyVT..DPHLLT.AVRYLASPAVSEDDLKILAE------AVLS-.PG....RLRKDP..EM------AKRVIETVMLGLDRNRFPWVSED.....REP.....SQAERE-MAIISTTALIA.T.-.-.--.-QR.VQTDRRnsaknvQED.AVAEYL.LSI.G..LTQVANRS-V.R.TA..R.D....LPSPGE.FCRESLF-.........--GSR.....---KADLIVSLWDGR----AMPTECKVSNSSTNSVKRLNNDAAKKA.KTWNEeF...GS..ANTVpAAVLSGVF.KVHNLEQAQ....A.DDLTIFW..............
A0A179B407_9ACTO/59-290 ..........................ltrlrdqahel----..--...---.--..LT..RHGYLT.EIRYLTSPSVSEDDLKVLTD------AKLS-.HS....YLEKNP..GA------AQSIIDVVLLGLDRERFPWLGEN.....RMP.....TAEENT-AAIVSTAALIA.N.-.-.--.-QK.VQTARRsaaknlQED.EVAKAL.LAS.G..YVEVERRSVD.N.FS..R.I....-PGPGE.FCKESLF-.........--GGR.....---KADLVIGLWDGR----AMPTECKVSNSSTNSVKRLNNDAAVKA.KVWLReF...GT..ASCIpAAVLSGVF.KVHNLLSAQ....K.NDLTIFW..............
A0A2V1H7F9_9GAMM/53-304 ...................................sy--LR..DI...SPE.TM..QE..TPSILS.TLRMATCPPLAVDRLIGLAGVNPSLVKAMEK.DN....RLPVRI..AADVLDRELQKIGDIVERMADPDIFVWLARG.....DEP.....TQEEIHRAATIVADRLCG.A.Q.A.NP.IIR.NEQEKR......QLA.KIKVWL.EAR.G..YTEIGSNARV.N.FQ..N.M....DPGTFS.FRLNVKV-.........-RSDT.....INIPVDAVIMPLSANKGDLPLLIEAKSAGDFTNTNKRRKEEATKMV.QLKQS.Y...GD..SVSF.VLFLCGYF.DSGYLGYEA....A.EGIDWIW..............
K9W514_9CYAN/53-308 .....................................TNLT..NI...TPD.VL..RQ..HPSVLP.ILRMAAAPPIARDRLIGLAGVSPNLVKNMEE.QQ....RLPPRM..NSATLDAELMKISQIIMRLTDKDIFSWLDTR.....QPP.....TDAEVHRAATIVADRLCG.A.V.S.DP.IIR.NAQERR......QLA.TIRQWL.EQR.G..YSYIGAGTGL.S.FE..R.I....QPGTFA.FRLNIPVL........lQGGSK....qVNIPIDVVVMPLQSNFGQLPLLIEAKSAGDYTNPNKRRKEEAIKIA.QLKSN.Y...GD..NVRF.ILFLCGYF.DSGYLGYEA....A.EGIDWLW..............
A0A1W6Z3X0_9BORD/54-290 ...............................ddlapg----..AI...TDD.KL.aDA..YGAGLGeAMRYLAGPPISEDDLRVIAD-----VESTA-.PG....VLRKDR..NA------LRKVFDVIERVIDPHRFPWVERG.....EAP.....TAPQRE-AALLASSVLLA.A.-.-.--.-QR.IATERRnegkdtQET.KVKDYL.RSL.G..FTEAPAVP--.-.IN..T.Iv..rGPQPMQ.FCAECQL-.........--GER.....---KADVVVRLHDTR----LLAIECKVSNSATNSVKRLNNDAAVKA.EYWIKqF...GT..AQVVpAAALAGVF.KVLNLEQAQ....A.RGLSLFW..............
A0A2U1VTB4_9PROT/68-298 .........................pevvrrilrdge----..--...---.--..--..---LFD.ALRYVAGPPISEDDLYTLVT-------R--S.AD....RLKKSD..LL--RDEVAMQVFGMICRLADPHRFPWIATG.....RRP.....RYHELR-NAVLMTAAVHA.P.-.-.--.-QT.LAAERRgy.graVEK.MLKDRL.DVL.G..LRCVPTPNGG.K.INapK.L....APDSGQ.YYGECTL-.........-YGRR.....----VDILIGTRHGR----IVAVESKDSNSAVNSVKRVANDTAGKG.EKWRKaY...GE..QVVL.VGLISGVF.KLETLKAAQ....D.SGLYLVW..............
A0A1R4HQQ6_9MICO/56-290 ....................................v-DLT..QLr.dQAA.EL..LA..EPDVLT.SARYLAGPPISADDLKELAG-----DVSLA-.PG....RLRADP..AM------AQRVIDTILLGLDRVRFPWVSED.....REP.....TDAERE-IAVIATAAMIA.T.-.-.--.-QK.VQTARRneakdeQEE.AVAAIL.NEN.G..FTQIATRPIL.N.IS..H.-....FPDVGE.FCRESDF-.........--GGR.....---KADLVVRLWDGR----VMPIECKVSNSSTNSVKRLNNDAAVKA.GVWLSeF...GT..ATVVpTAVLSGVF.KIHNLENAQ....T.RGLSLFW..............
D6CQ51_THIA3/53-308 ....................................g-NLT..NI...KPA.LL..RQ..HPEILP.TLRMSTCPPIAVDRLIGLAGVSTTLVKSMEL.DK....KLPVRM..PIVVADAQLVKIGTIIEKMADPDIFVWIGRT.....EAP.....TEVEIHRAATIVADRLCG.A.V.A.NP.IIR.NAQEKR......QLA.AIKTWL.EAR.G..YKQIHGGDGV.K.FN..A.M....QPGTFS.FRMNVPVK........lEGGVQ....qVNIPIDAVIMPKTAKAGDFPIFFEAKSAGDFTNTNKRRKEEAVKMA.QLRST.Y...GE..QVRF.NLFLCGYF.DSGYLGYEA....A.ESIDWVW..............
A0A0D5LT20_MAREN/61-291 ..........................vdasviadlmr----..--...---.--..--..NDDSRR.AFCYLTAPPISEDDLKTLVE------ASIA-.PT....RLEEHP..DS------AEKLRGIIFRILDPHRFPWVKEG.....RDP.....DPHERS-AAIIASAALVS.A.KkV.ET.FRR.NDAKDR......QEE.KVKELL.RSL.G..YTEIPKRDIL.-.NA..S.A....APAVGE.FMGETPL-.........-AGAK.....----ADVVATVPSGR----IMAIECKVSNSKVNSYKRIVHDTGGKA.TIWHDqL...GR..ANVLaSAVLSGVF.SVSNCETVQ....NdKGVYLFW..............
A0A1C3EE48_9GAMM/53-307 .....................................NNLT..NI...SAE.NL..EL..YPSVLP.MLRMTTCPPIARDRLIGLAGVSSNIVLNMEK.QG....RVPPKM..KHAELIEQLGMIGSIIEEMADPDIFVWKNRG.....DCG.....TKDEVHRASIIVADRLCG.S.V.A.DP.IIR.NAQEKR......QLD.AMKEWL.EAR.G..YRELEAGEVD.D.WL..S.M....PNGTFS.FRFNVPVQ........lENSKK.....INIPVDAVIMRKNAKEGDFPALFEAKSAGDFTNTNKRRKEEAVKMQ.QLRRT.Y...GE..GISF.DLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A2U2MYL1_9GAMM/56-289 ....................................h-DLK..SM...TADqVV..SI..FEDNLGdALRYLAGPPISEDDLKVLAD------ASLA-.PS....RLKQDD..QA------AERILSTIVQALDSKRFPWVAEN.....REP.....TDAEKR-AAVLTSAALIT.A.-.-.--.-QR.VSTLRRndgknkQEG.GVKEFL.RGI.G..FQEIAPRT-I.R.TL..A.D....APGAGQ.FCGECLV-.........--GSR.....---KADIPIRLYDGR----LMPVECKVSNSSTNSVKRVNNDASVKA.GIWRReL...GE..NQVVpAAVLSGVF.NVRNLKQAQ....D.SHLTLFW..............
A0A4R5ZX96_9RHOB/53-308 ....................................a-NLT..DV...TPD.IL..RQ..WPGVLP.TLRMSTCPPLAVDRLIGLAGVSSSLVKAMEQ.HQ....RLPPRM..KAALLAEDLEKIGTIIEKMADPDIFVWIGRT.....EAA.....TETEIHRAATIVADRLCG.S.V.A.NP.IIR.NAQERR......QLA.YVADWL.EAR.G..YTKLPDGYNG.T.FR..E.I....PPGTYS.FRMNVPVGg.......eNGGKT.....INIPVDAVIMRREAQEGEFPLLVEAKSAGDFTNTNKRRKEEAQKIN.QLRNT.Y...GP..DVEF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A285NS44_NATPI/50-287 ....................................n-NFR..DV...DID.FV..RE..NPITVR.ILRYLTEPILSRDKFSEYCDVGDQTLRKYEDyED....DTTPQP..NT------AEKIIGTFEEFRNETLLPWLEVE.....QMEyheydEETLVKKLQTAIAYNIAT.S.E.A.NT.EYR.NWRATI......QHD.AINDEL.FEA.G..FEKVNVDD--.-.VD..E.I....GPGE--.YVLELSV-.........-EGKE.....----ADFAIRNRDSD----LFLVEAKMSGTEINFHKRRKEM-IDDY.NDWTD.G...RP..DSEI.VAVIGGVI.DTDDVERLE....E.VGITVFW..............
D8FT64_9CYAN/53-308 ....................................a-NLT..NI...TSA.LL..QQ..HPEVLP.ILRMAAAPPIARDRLIGLAGVSPNLVKNMEE.KQ....RIPPRA..DIATLDAELTKISQIIARLLDKDIFPWLESR.....QQP.....TDSEVQRAATIVADRLCG.A.I.S.DP.IVR.NAQERR......QLT.MIRQWL.EQR.G..YSYVRGGAGL.S.FE..T.M....QPGTFS.FRLNIPVL........lQSGTK....qINIPIDVALVPIDSSPGEFPLLIEAKSAGDYTNPNKRRKEEAIKMT.QLRSN.Y...GN..NVRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A1M5Y8L3_9RHOB/53-307 .....................................SNLT..DI...KPE.TL..KA..WPGVLP.TLRMATCPPIAVDRLVGLSGASKNLVKKLE-.EG....SLPPRM..VEADLNSDLDKIGDIIEKMADPDIFVWLGRT.....NPA.....TKEEVHRAATIVADRLCG.A.V.A.NP.IIR.NAQEQR......QLA.YMAKWL.DAR.G..YTKLPDKHDF.D.FR..S.M....PPGTYS.FRMNVPVGd.......lDGGRT.....VNIPVDAVIKRLSAAEGDFPLLVEAKSAGDFTNTNKRRKEEAQKVN.QLHAT.Y...GK..DVEF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A849HLF1_9MICO/27-261 ....................................v-DLT..EL...SNQ.AVdlLT..QPEQLT.AVRYLASPAISEDDLKVLAE------AVLS-.TA....RLRAEP..DM------ARRVIDTVMLGLDRERFPWVAEN.....RDP.....TEAERA-TAVVSTAALIA.T.-.-.--.-QK.VQTARRndskklQEH.AVAEIL.LAN.G..FTQVPPRTIT.N.VS..H.-....FPAPGE.FCGESLF-.........--GTR.....---KADLVIRLYDGR----AMPTECKVSNSSTNSVKRLNNDAAIKA.ETWLKeY...GT..QTCVpAAVLSGVF.KIHNLLAAQ....NdKGLTLFW..............
A0A074JVI7_9RHOB/53-307 ....................................a-NLT..DV...TPD.IL..RK..WPGVLP.TLRMSTCPPLAVDRIIGLAGVSPNLVKNLE-.QN....KLPARM..KRADLDAGLTMIGDIIEKMADPDIFVWIGRD.....DPP.....TETEIHRAATIVADRLCG.S.V.A.NP.IIR.NAQERR......QLA.YVAEWL.EAR.G..YKRLPDGFNG.T.FR..D.M....PSGTYS.FRMNVPVG........gEDGNR....aINIPVDAVIMRRTAKEGDFPLLVEAKSAGDFTNTNKRRKEEAQKVN.QLRHT.Y...GA..DVQF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
L7LQC5_9ACTN/56-290 .....................vdltllkehavdllvr----..--...---.--..--..-SEMRT.AIRFLASPWISEDDLKVLAN------TTLS-.AQ....RLRAED..GA-----GAQRVIDTILMGLDRSRFPWVSED.....REP.....TQTERE-VAVISTAALIA.T.-.-.--.-QK.MQTARRneskneQEE.LVTDYL.IGQ.D..WTQVPTRT--.-.IS..T.Ln..dAPAPGE.FCRESKF-.........--GTR.....---KADLIVRLQDGR----VMPIECKVSNSFTNSVKRLNNDAAVKA.KAWIAeF...GT..LGAVpTAVIAGVF.KVHNLKAAQ....D.DGLTILW..............
K9U9Q7_CHRTP/53-309 .....................................NNLK..NL...QPE.IL..RQ..NPSILP.TLRMCTCPPIARDRLIGLAGVAKSVVERMEV.EG....KLPVRL..TGDRLDEQLRKITNIVSRLADRDIFTWLDTE.....QKP.....TESEIYRAATIVADRLCG.S.S.A.DP.IVR.NAQEAR......QLR.EIAAWL.NRR.G..YRLLPADRRV.R.FD..E.M....LPGTYS.FRLNIPVNl......ssEDGKT.....VNIPVDAVIMRNTARRGDRPLLVEAKSAGDFTNVNKRRKEEARKIQ.QLQAT.Y...GN..TIEF.VLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A5N5RLD6_9BIFI/60-312 ...................................dy--LR..AL...TEQ.YL..WD..NPEDLA.IARMFCAPPIARERLAGLAQVSKTIVQSME-.KG....SVPRGR..SRLQRREAIRRIIPVLRHLIDTQLCAWLKEG.....TRP.....SEREIEIASCVAGDRLCG.S.L.T.DP.LIR.NEQEHR......QLS.KLDTYL.NAR.G..YLRVENPSIQ.A.F-..D.M....KPGTYS.HHKNVSMYkn....atdES--Dg...mVNTPVDMAIMPFNST---RPLLIECKCAGDATNTNKRRKEEDTKVS.QLRGT.Y...GD..-VTL.YLFLCGYF.EATYLGYEA....A.NHMDWIW..............
A0A3S2YR16_9HYPH/50-285 ...................nylrdiaaaltvdarhsl----..--...---.--..--..------.VFRQLLSPPLSQDQFKLVCP---EWSKTSE-.--....----NS..GKALSEAAARSTATAIYSRLDYTLAPWITGR.....RAA.....TRSDIT-LFLKVVAVLLA.M.-.-.--.-QR.IQTARRkrlaneQED.AVVSLL.GQY.G..WTRLPSKT-I.D.IR..A.A....VPA-KH.FMHKTRFA.........TATTT.....-PQEVDIACGLPKTY----VLAMECKVTNDETNSVKRI-NDVLKKA.EAWKKhW...GT..FVIT.AALLQGVI.APKDVQRLT....D.ADVEVFW..............
A0A3S8UD23_9RHOB/54-288 ....................................v-DLT..EL...DTT.ALdvLG..DPRLLE.AFRYLAGPPISEDDLKVLAD-----ASSLA-.RS....TLEGKP..EL------VQRLIGVVRQVLDRRRFAWVVER.....REP.....TEAERN-AAVLASAALMA.A.-.-.--.-SR.AQTRRRtlgkdqQEE.MVKAAL.REL.G..FMEVPSRT--.-.IK..T.Is..hAPSPGQ.FCGESVL-.........--GNR.....---KGDIIVRLWDDR----VMPIECKVSNSSTNSVKRLNNDAAVKA.TSWKTdF...GL..RQVVpSAVLSGVY.KLHNLRDAQ....E.RGLALFW..............
A0A1H1DJE6_9GAMM/31-258 .........................glrlsgahnlvy----..--...---.--..--..------.--RQLLAPPLSQDQFALVCP---TWKKSSE-.--....-TKPKG..VS---EPIASSMETVITKRLDQGLVKWLAGA.....RPP.....SRRDVI-TVLRVISTLMA.Q.-.-.--.-QK.ISTARRsrlaaeQEH.AVADLL.LAD.G..WTRDPSRLID.T.RA..A.V....PPRHFM.HKTRFATN.........TATSQ.....---EVDIACGLSDTY----VLAMECKVTNDETNSVKRIN-DVIKKA.GAWAShW...GS..FVKS.AALLQGVI.HPRDVQRLS....D.AGIHVFW..............
A0A6F8YIF9_9ACTN/58-285 .....................................NNLR..NL...SGE.TV..KS..DPTLFQ.TLRYFCGPPISEEDLWTLVG-----GPK---.FK....KLPDDW..AD--------ETAAVISLVLDPVRFPWVELD.....RDP.....TEIERE-KAVLSTTVLLA.S.R.L.IGtRRR.GSASLR......QEA.AVGKIL.HDA.G..YDFDATRAAI.T.VL..D.S....LPR-GH.YSKERKV-.........--AEA.....---KCDVPVRLRDGR----LLAVECKVSNGPKNGWKRVVREVGGKA.EIWRQvF...GK..QVIT.AVVLAGVF.DLSCLEQAQ....R.GHVMILW..............
A0A2H6BA92_9HYPH/54-281 ....................................e-DLT..KI...EGQ.DL..LS..RKGLWQ.ILRYMCAPRISEEDLWTLVG------KKFK-.--....NVPKNY..--------AEKSAQVISDLVDLKRFPWVLAG.....RIP.....STEERD-AAVMATATLLA.H.-.-.--.-ER.LGTSRRggaskkQED.AVSEAL.VLA.E..LTIDASRR--.P.LA..A.L...dGLARAH.FSRERKV-.........--GSA.....---KCDIPIRLKDGR----LLALECKVSNGPKNSWKRLQREVGGKA.ETWRNaY...GS..QVVT.GALLAGVY.DLKCLSDAQ....NnQNVALFW..............
A0A4V1A3G0_9BACL/27-282 .....................................EDLT..NI...SPE.KI..KQ..HPSIVS.VLRMCTSPPIARDRLTGLAYANGSIVKTLE-.EG....KLPKRM..KKEELERNLTAICGVIIKLLDKDIFTWLAEG.....KKP.....NNEERYRASSIVADRLCG.S.V.A.DP.IIK.NAQEQR......QLK.LIDDFL.QKR.G..YVKLIHPSDK.P.IT..E.M....KKGTYS.FRMNIPVIl......enDNDKK.....VNIPIDVVIQRKNAKDVEYPILIECKSAGDFTNTNKRRKEEATKIR.QLQAT.Y...GK..EIKL.ILFLCGYF.DSGYLGYEA....A.EGLDWVW..............
A0A2U2MXE6_9GAMM/55-288 ....................................l-DLK..SM...TAD.QV.aRV..FEDNLGdALRYLAGPPISEDDLKVLAD------ASLA-.PS....KIKEDN..HA------AERILSTIVQALDSKRFPWVVDN.....RQP.....TDAEKR-AAVLTSAALIT.A.-.-.--.-QR.VSTLRRndgknkQEG.GVKNFL.RGI.G..FQEVSSRT-I.R.TL..A.D....APSVGE.FCSECLV-.........--GSR.....---KADIPVRLYDGR----LMPVECKVSNSSTNSVKRVNNDAAVKA.GIWRReL...GE..NQVVpVAVLSGVF.NVLNLIQAQ....E.SHLTLFW..............
J1GS95_9ACTO/55-288 ................................vdltr--LS..NL...AVE.LL..-T..NPQRLT.AIRYLASPAISEDDLKVLAD------AALT-.PK....RLNADP..DM------ARRVIETVLMGLDRERFPWVAES.....REP.....TESERA-TAVVSTAALIA.T.-.-.--.-QK.VQTGRRneakktQEG.AVADAL.RAA.G..FTEAPTRAVT.-.--..N.Ms..hLPAHGE.FCAEALF-.........--GSR.....---KADLIVRLWDGR----VMPTECKVSNSSTNSVKRLNNDAAVKA.RTWIQeF...GT..VTCVpAAVLSGVF.KTHNLTSAQ....A.DGLTLFW..............
A0A073CCG9_PLAAG/62-317 ....................................a-NIT..NI...TPA.IL..QQ..YPSVLP.ILRMATAPPIARDRLIGLAGVSSNLVKNMEE.KE....RIPPRI..DRGTLDTELAKIGKIIARLVDKDIFSWLDTG.....RQP.....TDTEVHRAAIIIADRLCG.A.I.S.DP.IIR.NAQERR......QLA.TIRQWL.EQH.G..YSYIGGGTRL.S.FE..R.M....LPGTFS.FRLNIPIL........lQGGTK....qINIPIDIVIKPIQSSPSQLPLLIEAKSAGDYTNPNKRRKEEAVKMA.QLRNN.Y...GE..NVRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A0T1WGM3_9MYCO/58-285 ....................................d-DIQ..NL...TGA.VF..KA..DPQAWQ.ACRYLCGPPISQEDLWTLVG-----------.GP....KFRSVP..PA-----YAEDTAEAIRVVVDPVRFPWLAQG.....RPP.....WPDERE-MAIMATTVLWA.A.-.-.--.-QQ.TGTERRgeassrQET.MTAKTL.DDA.G..LTLEVSRAPI.Q.FI..D.D....MPRGG-.YSRERRL-.........-AGAK.....----CDVPARLFDGR----LLALECKVSNGPKNGWKRVNREVGGKS.DSWRAhF...GS..QALT.GVILAGVF.DLSCLVTAQ....D.RGVTILW..............
A0A2M9HNM3_9BIFI/59-293 .......................dqlrnladmatqlf----..--...---.--..--..EEGCLD.TLRYMERPTLSADDFKKLSE------TNTDA.KG....KLSQPE..TA-------VMAMDYLRRNLNTRLFPWLDSD.....VAP.....ADSDLI-AAKCAVAALVAdQ.K.T.KT.MLR.NKQSHA......QEE.AVRAALvNDA.G..YTKVAAHD-F.R.ML..A.E....GPKPGEvFHKETSI-.........-DGVK.....----ADVVFGLYDGR----VMALECKVSNTAVNSYKRLNHETVDKI.VKWNNmF...GS..NGIVgGCVLQGVF.AVDNLVSAQ....Q.AGVAMFW..............
A0A563ADK4_9BACT/53-307 ...................................nf--LA..DI...SPA.KI..IE..HPEILP.ILRMSTVPPIARDRLTGLSQAPKSLVDSIDK.HK....RIPPRI..TKDMLDSGLEKISTTLQNMLDADIFTWIGTD.....RAP.....TQDEEDRASIIIADRLCG.M.V.A.DP.IIR.NAQEQR......QLA.SVRQWL.EVH.G..YKMVGKTDKS.N.PR..T.M....QPGTFS.FRLNIPVI........lDGGLT.....VNIPVDAIIQPKNAKSGTMPLLMEAKSAGDFANTNKRRKEEAVKFS.QLKRT.Y...GD..DVKF.FLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A378TF56_9MYCO/17-244 ....................................d-NVR..NL...TGD.LF..IG..DPQAWQ.ACRYLCGPPISQEDLWTLVGGS-----KFR-.--....SVPANL..----ADA----TAEAIRVVIDPVRFPWLEEQ.....RAP.....TEDERE-TAILATTVLWA.A.-.-.--.-QQ.IGTERRgeassrQES.LTAQAL.SDS.G..LELEESRTAV.Q.FI..D.D....MPR-GS.YSRERRL-.........-AGAK.....----CDVPARLLDGR----LLALECKVSNGPKNGWKRVNREVGGKA.ETWRAhF...GS..QALT.GVILAGVF.DLSCIKAAQ....T.AGVIILW..............
A0A844MGF6_9CYAN/53-308 ....................................a-NLT..NI...TPT.VL..RQ..HPSILP.ILRMATAPPLARDRLIGLAGVLPNLVKNMEE.KS....RIPPRM..DSGLVDAELMKIGQIITRLADKDIFPWLENG.....LEP.....TETQVHRAATIVADRLCG.A.L.T.DP.IVR.NAQERR......QLA.LIRQWL.EQR.G..YSYVRGGAGL.S.FE..T.I....QPGTFS.FRLNIPVS........lQSGSK....qVNIPIDIVIMPLQSNPGDLPLLIEAKSAGDYTNPNKRRKEEAVKIA.QLRLN.Y...GN..NVRF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A1BGJ7_CHLPD/15-270 ....................................g-NMT..AV...TPA.VI..CD..HPDILP.TLRMSTCPPLAVDRLIGLSGVSSNLVKSLEL.RK....KLPSKM..NSGLLDEDLHRIAAIIVKMADPDIFVWLGRK.....TQP.....DNDEIHRAATIVADRLCG.A.V.A.NP.IIR.NAQEKR......QLA.AIKSWL.EAR.G..YRQLQNGEAV.R.FD..S.M....PPGTFT.FRMNVPVD........lEGGVK....rVNIPVDAVVMPGKSKKGALPVFFEAKSTGDFTNTNKRRKEEAMKMS.QLRST.Y...GR..NVRF.NLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A437J996_9SPHN/52-286 .............................dylrdipa----..--...---.GL..SE..SGLHLT.ILRHLMAPPISQDQFALLCA---DYPKRAE-.--....-ITGRG..VS---VAAATAVASAFLAGRDRVLTRWLDGN.....GQP.....TSNQIR--NLLRGVVPLL.S.-.-.--.VQN.TATVRRgrmsveQEA.AIVALL.TDR.G..WTRQSSGLIS.S.LT..D.V....KPQHFL.HKARFATK.........TRPQ-.....---EVDIAC----GLPGTVVLAMECKVTNDETNSVKRIN-DVLKKA.AAWQEhW...GS..FVRT.AALLQGVI.AFK------....-.-------dvdrllegrvevfw
K9T9V4_9CYAN/53-309 .....................................NNLK..TL...HPE.IL..RQ..NPGILP.TLRMCTCPPIARDRLIGLANVAKSVVDCMEV.LG....KLPVRL..TEARLDEELRKITDIVARLADRDIFPWLDSN.....QTP.....LESEIYRAATIVADRLCG.S.S.A.DP.IVR.NAQEAR......QLR.EIAAWL.DSR.G..YRLLPASQRV.K.FD..E.M....PPGTYS.FRLNIPVNl......aeEGGKT.....VNIPVDAVIMRKAAQPGDRPLLVEAKSAGDFTNVNKRRKEEARKVQ.QLNAT.Y...GN..TIEF.VLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
U5QC54_9CYAN/53-306 .....................................ENLT..DI...KPS.TI..RN..SPAILP.TLRMSTCPPLAVDRLIGLARVSPGLVKTMEQ.GK....RLPPQM..NVAQADTELARVADVIERLADPDIFVWIGRP.....APA.....TTQEIHRAAIIVADRLCG.A.V.T.NP.IIR.NAQEAR......QLA.AIKAWL.EAR.G..YTPAPNGI--.R.FN..T.M....QPGTFS.FRMNVPVT.........QSGRVq...sINIPIDAVIMPRTAAPGSLPIFFEAKSAGDFTNTNKRRKEEAVKMA.QLRTT.H...GL..GVQF.NLFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A7L5ZLJ8_9BACL/50-285 ....................................q-DLR..DL...RTA.LL..AD..GKHMLX.-FRHLLAPPKSQDQFKLLCD-EWSKVSEIS-.--....GRPQRP..DA------VLAVSKVLVQWMDSEIAPWLIAN.....RDA.....TEVERE----LLIERVIS.F.I.A.PK.LTE.TQKRNRls..aeQER.DVVXAA.TGL.K..WTQLPSVTID.V.RA..A.I....PPKHFM.HKTRFATA.........TTT--.....-AQEVDIACGFSSSY----VAAMECKVTNDATNSVKRINDVLKKAA.AWKSH.W...GS..FVET.AALLQGVI.KPEDVQRLT....D.EGVKVFW..............
A0A2V3JHF6_9EURY/52-304 .....................................NDLL..DI...TVD.SI..GA..NPGALQ.ILRMTTAPPLARDRLIGLSHCNKNLVIRMER.KG....ELPVRM..NETELYKNLESICKIVTELLDIDIFPWISLG.....KKP.....TDHERERASTIIADRLCG.A.V.T.DP.IIR.NAQEQR......QLN.LIREYL.ETK.S..YTHVEHLSGT.P.LT..D.I....PQGTFT.FRMNVPA-.........--GDDl...sINIPVDVVIQPKKLRTSKLPFLIEAKSAGDYTNVNKRRKEEATKIR.QLKSA.Y...GS..EIQL.ILFLCGYF.DAGYLGYEA....S.EELDWIW..............
A0A1H1YE88_9ACTN/52-236 ...................................dg--LQ..AL...SPA.LL..RR..RPQHLA.TLRMTTAPPMARERLAELARAERPVIHALE-.QG....RLPSSI..SSGDLDAQLGRICRVLTHCVDP---VLVGAG.....RTA.....ADRDH--VTMLVADRRCD.A.V.A.DQ.ILR.QALRDH......RRT.LLRSWL.EDR.G..YTQQPGTR--.S.TP..A.L....VPGSFR.FGPQRVEP.........AAGGR.....-GLEADLLVAP-----------------------------------.-----.-...--..----.--------.---------....-.-------agrgprlvalqe..
A3X310_9BRAD/1-65 ....................................m----..--...---.--..--..------.-------------------------------.--....------..-------------------------------.....---.....------------------.-.-.-.--.---.------......---.------.---.-..----------.-.--..-.-....------.--------.........-----.....--------------------IALEAKDSSSGLNSVKRLNNDTAAKA.KHFATeG...GK..NIVN.VALLSGVF.KLSSLVSAQ....N.SGLFLVW..............
U1YI14_9BURK/53-311 .....................................ENLT..NI...RPE.IL..RK..WPGVLP.TLRMSTCPPLAVDRLIGLAGVSSSMVKRMEK.EK....QLPVRM..AAANIDHELVKIAAVIERLADPDIFVWIKRS.....DPA.....TEAEIHRAATIVADRLCG.S.V.A.NP.IIR.NAQEQR......QLA.YIGQWL.EAR.G..YTKLPDRSNV.T.FD..T.M....PPGTYS.FRMNVPVAk.......gVGGDE....sINIPVDAVVMRKTAAKGDYPLLIEAKSAGDFTNTNKRRKEEAQKVN.QLRAT.Y...GHirPIEF.ILFLCGYF.DSGYLGYEA....A.EGIDWVW..............
A0A1I1YKD5_9BACL/52-319 ....................................d-NLK..SI...NPE.II..MN..NPTIVP.TLRMCTAPPLARDRLTGLGYLNKSILSSMED.KG....AVPPKM..KELELVRNFTAISGVITKLLDKDIFTWLEDG.....HVP.....TDEEVYRASTIIADRLCG.A.V.A.NP.IIK.NAQEQR......QLA.LIASYL.EER.G..YDRIKHPSDK.P.IT..E.M....KKGTYS.FIMNVPIYqsevtsedgESGDNegaskVNLAIDVVIQKKTAQDGEYPILIECKSAGDFTNTNKRRKEEAIKSI.QLRNT.Y...GS..ELKL.YLFLCGYF.DTPYLGYEA....A.EGLDWIW..............
A0A0P4UKT0_9CYAN/53-309 .....................................NNLK..TL...QPE.IL..RQ..NPGILP.TLRMCTCPPIARDRLIGLANVAENVVKRMEV.KG....KLPVRL..TDARLNEELGKITDIVTRLADRDIFPWLNTN.....QTP.....LESEIYRAATIVADRLCG.S.S.A.DP.IVR.NAQETR......QLK.EIATWL.DAR.E..YRLLPAGQRV.K.FD..E.M....PPGTYS.FRLNILVNs......aeEGGKT.....VNIPIDAVIMRKTAQPGDYPLLVEAKSAGDFTNVNKRRKEEAKKVQ.QLNAT.Y...GN..TIEF.VLFLCGYF.DSGDLGYFA....A.EGIDWVW..............
A5USP4_ROSS1/56-179 ....................................d-DLR..RL...DVT.TL..RS..NPGILP.TLRMCTAPPLAVDRLVGLAGVSKNLIERME-.QG....NLPGKT..TSADLDRALTKICDILSQLLDRDIFPWLVNG.....TAL.....DDRERDRSATIIADRLCS.A.V.A.NP.IIR.NAQEQ-......---.------.---.-..----------.-.--..-.-....------.--------.........-----.....----------------------------------------------.-----.-...--..----.--------.---------....-.-------lg............
A0A087EKU8_9BIFI/52-304 ...................................dy--LR..SL...DEQ.YL..WD..NPENLA.IVRMFCAPPIARERLAGLAQVSKSIVQSMEK.GS....VPRGRS..HV-QRKEAISRMIPVLKRLTDTQLCAWLTEG.....SCP.....SDREIEIASCVAGDRLCG.S.L.T.DP.LIR.NEQEHR......QLS.KLDAYL.DAR.G..YWRVEDSS-V.Q.AF..D.M....RPGTYS.HHKNVGMYk......naTDASDg...mVNTPVDMAIMPFNSN---RPLLIECKCAGDATNTNKRRKEEDTKVS.QLRGT.Y...GD..-VTL.YLFLCGYF.EATYLGYEA....A.NHMDWVW..............
#=GC seq_cons .......................................lp..sl...pst.hl..ht..pPthLs.sLRhhsuPPlupDcLhsLus.....spshc..tt....clssch..st......hp+lssllpchhD.chFsWlsps.....ptP.....T-pEhc.AAslsustLsu.u...s.ps.hhR.sup-cR......Q.s.tltphL.csp.G..applssts.h.p.hp..s.h.....Pushp.Fphps.l...........tGsc.........sDlVlt.hsup....slhlEsKsusshTNosKRhpc-Aschu.phhts.a...Gs..ssph.shhLsGhF.css.Lshtt....s.cGlshhW..............
//
