#=GF ID   RHA1_ro05818_N
#=GF AC   PF20859.1
#=GF DE   Hypothetical protein RHA1_ro05818, N-terminal helical domain
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   ECOD:3768.1.1
#=GF GA   27.00 27.00;
#=GF TC   28.00 28.00;
#=GF NC   25.90 24.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   23024343
#=GF RT   Gene cluster encoding cholate catabolism in Rhodococcus spp.
#=GF RA   Mohn WW, Wilbrink MH, Casabon I, Stewart GR, Liu J, van der
#=GF RA   Geize R, Eltis LD;
#=GF RL   J Bacteriol. 2012;194:6712-6719.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found at the N terminus of Hypothetical protein
#=GF CC   RHA1_ro05818 from Rhodococcus jostii (Swiss:Q0S4E1). This
#=GF CC   protein is thought to be a thioesterase involved in the
#=GF CC   metabolism of cholate [1]. This protein has a 4HBT domain
#=GF CC   (Pfam:PF03061) at the C-terminal. The N-terminal domain shows an
#=GF CC   helical fold.
#=GF SQ   59
#=GS A0A0K2YFL0_9NOCA/20-76  AC A0A0K2YFL0.1
#=GS Q0S4E1_RHOJR/18-74      AC Q0S4E1.1
#=GS A0A5J6FIC8_9ACTN/27-84  AC A0A5J6FIC8.1
#=GS A0A4V6TSZ2_9ACTN/16-73  AC A0A4V6TSZ2.1
#=GS E9SWP5_RHOHA/18-74      AC E9SWP5.1
#=GS A0A1P8YA91_9NOCA/18-74  AC A0A1P8YA91.1
#=GS D1AB88_THECD/5-62       AC D1AB88.1
#=GS A0A1G6S818_9NOCA/18-74  AC A0A1G6S818.1
#=GS A0A558DD11_9PSEU/6-63   AC A0A558DD11.1
#=GS R7WQ90_9NOCA/16-72      AC R7WQ90.1
#=GS A0A4V1A0Y2_9NOCA/18-74  AC A0A4V1A0Y2.1
#=GS A0A4R4S5B4_9ACTN/12-69  AC A0A4R4S5B4.1
#=GS A0A516X1D2_9ACTN/19-75  AC A0A516X1D2.1
#=GS V8D5E5_9NOCA/16-72      AC V8D5E5.1
#=GS A0A059MLI0_9NOCA/18-74  AC A0A059MLI0.1
#=GS A0A367F518_9ACTN/7-64   AC A0A367F518.1
#=GS A0A0Q7ZNP4_9ACTN/22-79  AC A0A0Q7ZNP4.1
#=GS A0A5Q0NP68_9ACTN/10-67  AC A0A5Q0NP68.1
#=GS A0A429FQE3_9ACTN/5-62   AC A0A429FQE3.1
#=GS A0A852R206_9ACTN/6-63   AC A0A852R206.1
#=GS A0A1Q9U1T9_9ACTN/5-62   AC A0A1Q9U1T9.1
#=GS A0A1H7JB62_9ACTN/13-70  AC A0A1H7JB62.1
#=GS A0A2X4TQY8_9NOCA/20-76  AC A0A2X4TQY8.1
#=GS A0A7V8NEZ4_9ACTN/23-77  AC A0A7V8NEZ4.1
#=GS A0A6H0ZXU6_9ACTN/22-79  AC A0A6H0ZXU6.1
#=GS A0A1E7KLL3_9ACTN/1-49   AC A0A1E7KLL3.1
#=GS A0A8J3R931_9ACTN/17-74  AC A0A8J3R931.1
#=GS A0A1C5BLA8_9ACTN/17-74  AC A0A1C5BLA8.1
#=GS A0A0D8I484_RHOSX/18-74  AC A0A0D8I484.1
#=GS A0A541BAT3_9NOCA/18-74  AC A0A541BAT3.1
#=GS A0A6G7YHQ3_9ACTN/10-67  AC A0A6G7YHQ3.1
#=GS A0A372J041_9ACTN/13-70  AC A0A372J041.1
#=GS A0A1W2DFK1_9PSEU/7-64   AC A0A1W2DFK1.1
#=GS A0A1H3DJ73_9PSEU/11-68  AC A0A1H3DJ73.1
#=GS A0A6B3GHC9_9ACTN/19-76  AC A0A6B3GHC9.1
#=GS A0A6B3HVE6_9ACTN/19-76  AC A0A6B3HVE6.1
#=GS V9XDB5_9NOCA/20-76      AC V9XDB5.1
#=GS A0A231H185_9NOCA/26-82  AC A0A231H185.1
#=GS A0A850JFW3_9ACTN/5-62   AC A0A850JFW3.1
#=GS A0A0D8I1N2_RHOSX/9-62   AC A0A0D8I1N2.1
#=GS A0A4Y9NBM4_9ACTN/1-24   AC A0A4Y9NBM4.1
#=GS A0A238UW59_9ACTN/5-62   AC A0A238UW59.1
#=GS A0A4R2DWM0_9NOCA/20-76  AC A0A4R2DWM0.1
#=GS A0A0H5CJC8_9PSEU/5-62   AC A0A0H5CJC8.1
#=GS A0A4R5BYV7_9ACTN/5-62   AC A0A4R5BYV7.1
#=GS A0A4R4P9E5_9ACTN/5-62   AC A0A4R4P9E5.1
#=GS A0A239NTR7_9ACTN/5-62   AC A0A239NTR7.1
#=GS A0A1I5JZ17_9PSEU/7-64   AC A0A1I5JZ17.1
#=GS A0A846XD24_9NOCA/20-76  AC A0A846XD24.1
#=GS A0A178X6V1_9PSEU/10-67  AC A0A178X6V1.1
#=GS A0A1X0UT59_9NOCA/18-74  AC A0A1X0UT59.1
#=GS A0A2N5WM86_9ACTN/1-53   AC A0A2N5WM86.1
#=GS A0A7Y9S3L0_9ACTN/18-75  AC A0A7Y9S3L0.1
#=GS A0A4R4XUU6_9ACTN/5-62   AC A0A4R4XUU6.1
#=GS A0A846Y941_9NOCA/20-76  AC A0A846Y941.1
#=GS A0A1Q5LZU2_9ACTN/16-73  AC A0A1Q5LZU2.1
#=GS A0A2S2BNZ2_9NOCA/18-74  AC A0A2S2BNZ2.1
#=GS A0A6B2RS91_9ACTN/35-92  AC A0A6B2RS91.1
#=GS A0A1G7ZV82_9NOCA/18-74  AC A0A1G7ZV82.1
A0A0K2YFL0_9NOCA/20-76             ....LTSAPQDTAVDHAAAAARRVVDALLRT-DRSNANLERVAEELNSIAEHLEEHAPAVAE.
Q0S4E1_RHOJR/18-74                 ....LTSPPDGSAVDRATDAARRVVDALLRT-DRGNANLERVAEELNSIAGHLEEHAPAVAE.
A0A5J6FIC8_9ACTN/27-84             ....LVAEARKEGVDAAVAAARRLITALLRSGDGTGADLDAVASQLDAVADRLTAGAPTVTD.
A0A4V6TSZ2_9ACTN/16-73             ....LTADPANDGVDAAVAAARRVVAALLHAGGNSAAEMNDVAGRLNAIAEHLEEHAPGTDE.
E9SWP5_RHOHA/18-74                 ....LTSAPQDAPVDRATAAARRVIDAMLRT-DRGNANLDRVAEELNSIADHLEEHAPEVAE.
A0A1P8YA91_9NOCA/18-74             ....LTSAPQDAPVDRATAAARRVVDAMLRT-DRANANLDRVAEELNSIADHLEEHAPAVAE.
D1AB88_THECD/5-62                  ....LNATATGRGVDAAAAAARRVIAALVRAGDISGADMTAVADRLNAIADELEAAAPGLRE.
A0A1G6S818_9NOCA/18-74             ....LTSAPQDAPVDRATAAARRVIDAMLRT-DRGNANLDRVAEELNSIADHLEEHAPEVAE.
A0A558DD11_9PSEU/6-63              ..at--TPAQPAGTEALAAAARSVVDAVVRAGDHCAERAAELAARLRAIADELDRCAPPLEE.
R7WQ90_9NOCA/16-72                 ....LTSPPADAPIDRATAQARRLVEALLRT-DRTRGDLAAVADELGRIADQLEAHAPDVSD.
A0A4V1A0Y2_9NOCA/18-74             ....LTSAPQEAPVDRATAAARRVIDAMLRT-DRGNANLDRVAEELDSIADHLEEHAPEVAE.
A0A4R4S5B4_9ACTN/12-69             ...e-HSGTRPAGVDAASAAARRVIDALLRSGDMTDADMAAVADRLNAVADDLEVGAPPLED.
A0A516X1D2_9ACTN/19-75             ....LTSTRGDAAIDRATHAARRLIDALLRA-DRDGTDLSGVAERLESVVDDLDAQAPAVQD.
V8D5E5_9NOCA/16-72                 ....LTSAPQDRPVDRATAAARRVVDALLRT-DRTNANLQRVAEELDNIAEHLEEHSPEIAE.
A0A059MLI0_9NOCA/18-74             ....LTSAPQDAPVDRATAAARRVVDAMLRT-DRGNANLDRVAEELDSIADHLEEHAPAVAE.
A0A367F518_9ACTN/7-64              ....LVSEPRDGGVDAAVAAARRIVDALLQAGEGTDADMTGVAKQLHAVADSLEDQAPAREE.
A0A0Q7ZNP4_9ACTN/22-79             ....LTAAPNNDGVDKAVVATRRVIETLLHAGDRTSAEMGAIASQLNAVADHLDEHVGPIDE.
A0A5Q0NP68_9ACTN/10-67             ....CSSPPVDGGVDAAVAAVRRLAEALLRTGDTAAVDLDDLARRITALSEEVEEHTPALD-t
A0A429FQE3_9ACTN/5-62              ....LQASPRRSGVDAASAAARRVIAALVRAGDISTADMADVADRLNAVADDLEAAAPALHD.
A0A852R206_9ACTN/6-63              ....LTARPDESGIDTAVAAVRRLAAALLAAGGRVDLDLDDLARRLSAMAGEVEGLAPELAD.
A0A1Q9U1T9_9ACTN/5-62              ....LQASARGCGVDGASAAARRVIAALVRAGDISTADMSDIADRLNAVADDLEATAPPLG-d
A0A1H7JB62_9ACTN/13-70             ....LTATPDNAGVDAAVAAARRVVTALLHAGGNSAAEMQDVAARLDAVADHLEQHAPPMAD.
A0A2X4TQY8_9NOCA/20-76             ....LTSAPQDTAVDRAASAARRVVDALLRT-DRNNANLERVAEELDSIAAHLEEHAPEVQE.
A0A7V8NEZ4_9ACTN/23-77             gaep-------TDVEEAAAAARRVVAALLHAGDRPGAELRDVAATLHGLADRLDAHAPATE-a
A0A6H0ZXU6_9ACTN/22-79             ....LTAKPNNEGVDSAVAAARRVIEALLHAGDRTSAEMGAIASQLTAVADHLVEQAGTVDE.
A0A1E7KLL3_9ACTN/1-49              ...m----------DGAAAAARRVISALLRTGDDTAADMAGMAKQLHAVADQLEEHAPARE-t
A0A8J3R931_9ACTN/17-74             ....LTATPRNKGVDAAVAAARRVVASLLHAGDGSAAEMEKIADQLNAIADHLDEHAPAVEE.
A0A1C5BLA8_9ACTN/17-74             ....LVAEPHKDGVDAAVAAARRVVTALLRAGDGTGADMNEIAARLDAVADGLTEKASSME-t
A0A0D8I484_RHOSX/18-74             ....LTSPPQDAPIDRATEAARRLIDALQRT-DRDNANLDRVAEELNSIVAHLEQHAPEVEE.
A0A541BAT3_9NOCA/18-74             ....LTSAPQDAPVDRATAAARRVIDAMLRT-DRGNANLDRVAEELNSIADHLEEHAPEVAE.
A0A6G7YHQ3_9ACTN/10-67             ....LTAVPNNEGVDAAVAAARRVVGALLHTGDRSPVEMAAVAAQLDAVAQHLERHAPTREE.
A0A372J041_9ACTN/13-70             ....LTAAPDNAGVDAAVAAARRVVAALLHTGGNSAAEMQDVAARLDAVADHLEQHAPTMAD.
A0A1W2DFK1_9PSEU/7-64              ...v-TAPVQQGGVQDVAAAARRVVDAIVRAGDAIAAQSGDLATALHGVADRIDLAAPPLAE.
A0A1H3DJ73_9PSEU/11-68             ....LTAISHNEGVDAAVSAARRVIASLLHAGDGSAAEMKEVADRLNAVADHLDEHAPAMDQ.
A0A6B3GHC9_9ACTN/19-76             ....LVAEPRQDGVDAAVRAARRLVTALLRSGDGTGADMAAVAKEIDAVTDRLTENAPAVPE.
A0A6B3HVE6_9ACTN/19-76             ....LVAEPRQDGVDAAVRAARRLVTALLRSGDGTGADMAAVAKEIDAVTDRLTENAPAVPE.
V9XDB5_9NOCA/20-76                 ....LTSAPQDTAVDRATAAARRVVDALLRT-DRGNANLERVAEELDNIAEHLEEHAPEVRE.
A0A231H185_9NOCA/26-82             ....LTSERRDVPVDRATAAARRVIDALLRT-DRANANLDRVAEELDSIADHLEQHAPVVAE.
A0A850JFW3_9ACTN/5-62              ....LQSGTRPTGVDAAVDAARRVIDALVRSGDMTDADMAGITDRLHAVADDLESSAPPLDD.
A0A0D8I1N2_RHOSX/9-62              .vin------PSPIDDAADGLRRLTDLLLRV-DENDPALVAVADELDRIEAALEQNAGPVE-f
A0A4Y9NBM4_9ACTN/1-24              ....----------------------------------MAEVADRLNAVADHVEDHAPPRE-a
A0A238UW59_9ACTN/5-62              ....LQAGSQATGVDAAAAAARRVLDALVRSGDLSGADMSDVADRLNAVADDLEEAAPPLRD.
A0A4R2DWM0_9NOCA/20-76             ....LTSAPQDSAMDRATAAARRVVDALLRT-DRANANLERVAEELDSVAVHLEEHAPEVKE.
A0A0H5CJC8_9PSEU/5-62              ....LTATPRNKGVDAAVAAARRVIETLLHAGDNSAAEMSAVADQLNAVADHLEDHAPSVHE.
A0A4R5BYV7_9ACTN/5-62              ....LQSGTRTGGVDAAAAAARRVLAGLVRAGDLSDADMSGIADRLNSVADDLEAAAPPLHD.
A0A4R4P9E5_9ACTN/5-62              ....LHSGTRPAGVDAAVAAARRVIDALVRAGDMTDADMSDIADRLNAVADDLDSSSPPVDD.
A0A239NTR7_9ACTN/5-62              ...l-PSGTRPAGVDAAVEAARRVIDALVRSGDMTDADMASVTGRLNAVADDLEATAPPLRD.
A0A1I5JZ17_9PSEU/7-64              ....LTADPHQDGVDAAVTAARRVIESLLRAGSGSTAEMGRIADQLNSVADNLDEHAPAMN-q
A0A846XD24_9NOCA/20-76             ....LTSAPQDTPVDRATAAARRVIDALLRT-DRANANLDRVAEELDSIADHLEQHAPQVAE.
A0A178X6V1_9PSEU/10-67             .lsp---VPNDDGIDAAVAAARRVVSALLHAGADSAAPMTDLARDLDRIAGQLEEHAPARQE.
A0A1X0UT59_9NOCA/18-74             ....LTSVSNDSAVDRATQAARRVIDALLRT-DRGNANLERVTEELISVAQHLESHAPAVEE.
A0A2N5WM86_9ACTN/1-53              ...s-----ADAAVDAAAAAARRVTVALLRAG-GAAPGLEEITARLEEVAERLEAAAPPLDE.
A0A7Y9S3L0_9ACTN/18-75             ....LTAIPKNEGVDSAVAATRRVISALLHAGDRTSAEMGAVAAQLNAIADHLDEHNGPVDD.
A0A4R4XUU6_9ACTN/5-62              ....LHAEGRACGVDGAAAAARRVIDALVRAGDISDADMSGIADRLNAVADDLEATAPPRDD.
A0A846Y941_9NOCA/20-76             ...i-TSSPRALPVDRATAAVRRVMDALMRT-DHASAELDRVAAELDAVADHLDEHAGTIE-q
A0A1Q5LZU2_9ACTN/16-73             ....LVAEPHKDGVDTAVAAARRVIAALLRAGDGSGADMNAIAARLDAMADGLTEQAPAIEE.
A0A2S2BNZ2_9NOCA/18-74             ....LTSPSDGAAVDRATEAARRVIDALLRT-DRANANLERVAEELNSIAEHLEEHAPAVAE.
A0A6B2RS91_9ACTN/35-92             ....LIADTREDGLDAAVTAARRVIASLLGTGDTADADLRRVAGTLHALADHLDSHAPPLKE.
A0A1G7ZV82_9NOCA/18-74             ....LTSARAGDPIDRATDAARRVVDALLRT-DRTNANLERVTEELDGIAEHLEEHAPAVAE.
#=GC seq_cons                      ....LsusspssuVDtAsAAARRVl-ALLRsGDpssAchscVAccLsulAD+LEpHAPslp-.
//