#=GF ID RecJ_C
#=GF AC PF20748.1
#=GF DE Single-stranded-DNA-specific exonuclease RecJ C-terminal domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE ECOD:7511.1.1
#=GF GA 25.00 25.00;
#=GF TC 26.40 72.90;
#=GF NC 23.60 20.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RC Paper describing PDB structure 2zxo
#=GF RN [1]
#=GF RM 20129927
#=GF RT Structure of RecJ exonuclease defines its specificity for
#=GF RT single-stranded DNA.
#=GF RA Wakamatsu T, Kitamura Y, Kotera Y, Nakagawa N, Kuramitsu S,
#=GF RA Masui R;
#=GF RL J Biol Chem. 2010;285:9762-9769.
#=GF RC Paper describing PDB structure 5f54
#=GF RN [2]
#=GF RM 27058167
#=GF RT Structural basis for DNA 5 -end resection by RecJ.
#=GF RA Cheng K, Xu H, Chen X, Wang L, Tian B, Zhao Y, Hua Y;
#=GF RL Elife. 2016;5:e14294.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found at the C terminus of Single-stranded-DNA-
#=GF CC specific exonuclease RecJ from Deinococci. This protein has four
#=GF CC domains that form a molecule with an O-like structure [1]. The
#=GF CC fourth domain (this entry) binds the C-terminal region of
#=GF CC Single-stranded DNA-binding protein (Pfam:PF00436) to
#=GF CC efficiently process broken DNA ends for homologous recombination
#=GF CC [2].
#=GF SQ 20
#=GS L0A4K4_DEIPD/544-715 AC L0A4K4.1
#=GS A0A072NKL7_9DEIO/543-691 AC A0A072NKL7.1
#=GS A0A841HXV5_9DEIO/538-713 AC A0A841HXV5.1
#=GS Q1IXZ0_DEIGD/544-688 AC Q1IXZ0.1
#=GS A0A1U7P0Q5_9DEIO/545-702 AC A0A1U7P0Q5.1
#=GS E8U9G6_DEIML/543-699 AC E8U9G6.1
#=GS A0A511N557_DEIC1/536-710 AC A0A511N557.1
#=GS A0A318SAB8_9DEIO/538-708 AC A0A318SAB8.1
#=GS A0A418VCL5_9DEIO/517-674 AC A0A418VCL5.1
#=GS H8GYI4_DEIGI/517-662 AC H8GYI4.1
#=GS Q9RVA3_DEIRA/474-627 AC Q9RVA3.1
#=GS A0A221SZH4_9DEIO/517-669 AC A0A221SZH4.1
#=GS F0RLG7_DEIPM/538-681 AC F0RLG7.1
#=GS A0A1W1VNM6_9DEIO/544-697 AC A0A1W1VNM6.1
#=GS A0A7C9M7Z4_9DEIO/517-678 AC A0A7C9M7Z4.1
#=GS A0A172TAY3_9DEIO/546-702 AC A0A172TAY3.1
#=GS A0A0F7JL70_9DEIO/537-694 AC A0A0F7JL70.1
#=GS C1D146_DEIDV/542-696 AC C1D146.1
#=GS A0A2K3V293_9DEIO/517-672 AC A0A2K3V293.1
#=GS A0A2Z3JI86_9DEIO/515-665 AC A0A2Z3JI86.1
L0A4K4_DEIPD/544-715 ......se--AEHASYP...PLPRLRPQEAMALLRR...GARAYADGPVAAYLRDNVPGVQFAQDGERWRG-..ELVLFCLPPEDDLRRWL......DSA..EVSFAWGPKTLDALEGNY..GFHRe..gLRLDPDPRVLAeigvlsalelgerdlW---Rsa.....slREAAAEAYRRWLWAQLYVGLGDEDWTRAVRLMVA-----strhn.
A0A072NKL7_9DEIO/543-691 ..slaaap------APA...PVPRLDPRAGIERLRA...GASAYADGAVAAYLAAQVPGLRLVPAGDPHPGG..ELILYSLPDEASLRQWL......GGG.gRVAFALGPKTLSELEGRL..TPAH....LQPTAD-----...............EA--N.........RAAAADAYRDWQWAHLYRVLDDEGWSAAVHHLLGLA---rap...
A0A841HXV5_9DEIO/538-713 legvedga-------FT...PLPRLSAQQALGALKEnpqRWAVYAEGEGRSYLERAHPAVRLLEPGESASS-..-VLLMALPPEEDLRRWL......QGA..EVAFAWGEKTLQALERPY..AWNLeglrLGD-LEPRILEelgir.....shlelD---HvdlwssptvREQAAEAYLRTCWARMYRRLDDASFAVAARALAGLAA--sp....
Q1IXZ0_DEIGD/544-688 ........LDSPYTDAP...PLPRLDPKEAMNHLRA...GASAYADGPVATYLREQVPGLTLLSPGAPHPGG..ELILYALPPEADLTRWL......GEG..RVAFAFGPKTLAELEGSL..AHHP....-------SL--...............-TGAE.........LEEAADAYRRWQWAHLYRVLDDAGWNAAVRHLLGLVQ--ap....
A0A1U7P0Q5_9DEIO/545-702 ......ld--LPVPDGL...DLPRLNPKDAMQRLTA...GASAYATPAVADYLRDNVPGVRLVEAGELWSGE..ELILYALPTEDDLCRWL.....lTGG..AVAFALGPKTLSELEGAL..TRHH....LSAPPANPLAD...............ATADEa.......hMARAADAYRRWQWAHHYRTLDNGGWTASVHAMLGLA---lpl...
E8U9G6_DEIML/543-699 llgaddar------PLP...PTPRLDPREAMRHLHA...GARAYATGAVREYLSVNVPGLALADDADTPDG-..EVIVYALPPERTLRAWL......TGGrtRVAFAFGPKTLAELEDGA..V--R....VAGPLRAHASD...............WSDPV........mRAGAADAYTRFMWAALYRALDDASFTRAVWHLAGLNPD-e.....
A0A511N557_DEIC1/536-710 ...lnlte----QDSTV...RVFRMGAREAISHLKNnpsRFAVYAENDGIPFLQKNCPEVRLLTPEEDAPR-..-ILLMALPPLATLERWL......QQA..EVTFALGDRNLAVLLETYqhGSEH....LTQHPRPEVLEelgvasfmdvpgtnvW---Ssa.....syREEALEAYLKTCIAQFFVRLSDQGFSTAVLQLF------aahhps
A0A318SAB8_9DEIO/538-708 .....leg---AS-DGP...RLPRLEPKDAMGRVRG...GTLAYADGSVADYLQTNVPGVRFVQPGERVRQ-..EIVLFGLPSEDDLRAWL......REG..HVTFAWGPKTLEALRGRY..GYHRe..gLALDADADVLAelgvrs...aielrgA---Elwr..sarwREDAADAYRRWLWAHLYEGLDDAGWSSAVLALTGVRAG-e.....
A0A418VCL5_9DEIO/517-674 legadgls-------VE...DTPRLNPREAMGRLSA...GAAAYAQNGVVDFLRDNVPGVHLLEAGQAFGGP..ELILYALPPEDDLRRWL......GTS..RVAFAFGPKTLAELEGSL..TLHH....LAAPPENPLSD...............ALKDEe.......rLERAADAYRRWQWAHNYRVLNDAGWVASVYAMLGLEP--gi....
H8GYI4_DEIGI/517-662 ...legqa----EGQET...DLPRLDPQEAVTHLRA...GAAAYAENGVVPYLTGQVPGLRLLGSGDRLPTDttEVILYALPAEADLRRWL......AQG..RVAFAWGPKTLKDLESA-..---G....LTPPSPAV---...............-----.........SETAAEAYRRWQWGHHYRVLSDAGWAASVRAMLGEDVG-e.....
Q9RVA3_DEIRA/474-627 ........LAGTEEGLP...TLPRLNPREAMTFLKT...GAAAYAEQGVATYLRDNVPGLTLLDTNAPHPGG..DLILYGLPPESALRRWLhe.aqeQGG..RVAFALGPKTLAELDAAL..TLAK....LLPDSHTEAA-...............-----.........QEAAADAYRSWQWAHHYRVLNDAGWSASVYAMLGLPVP-a.....
A0A221SZH4_9DEIO/517-669 .......m-AGPDVPGG...HLARLDPRAALARLHA...GAAAYATGAVAAYLRDNVPGLTLIQPGEEHPEG..TLILYALPDETDLVRWL......SGG..EVLFALGPKTLSDLEGQF..SAFA....GVPAPASTDAD...............DLR--.........RVRAARAYRQWQWAHHYRTLDDEGWARSVHAMLGMPVP-s.....
F0RLG7_DEIPM/538-681 ...laapq-----AQVAaarLAVRRTPEQVMARLKAvgrGVAVYAGETLRASLAARLPELHYLQPGDPLPAL..PLVLFDLPPTGVLERWLqe..rpA-AapPVTFAWGRETLAALDA--..----....-----------...............-----.........APQGAEGYHRFQWAHAYLTLDEAGWDGAVRALSGLGVE-e.....
A0A1W1VNM6_9DEIO/544-697 ........LDTLHGDAP...PLPRLDPREAMNHLKA...GASAYATGPVAAYLRDQVPGLTLTQAGETHPGG..ELILYALPAEADLKRWL......GEG..RMAFAFGPKTLAELEGSL..SRQH....LSPPSTNPLVD...............ARA-G.........METAADAYRRWQWAHLYRVLDDPGWSSAVRHLLGLED--ga....
A0A7C9M7Z4_9DEIO/517-678 .......l-DAPAPET-...STPRLDPRAALAHLRS...GASAYAQGAVADYLRDNVPGLTLAAAGEAHPGG..ELILYALPAEDDLRRWL......LGG..RVAFAFGPRTLADLEGSL..TRHH....LSAPPSNPLQE...............LGADDlnsp.ytsrLETAADAYRRWQWAHHWRTLDDAGWSASVLAMLGVA---plq...
A0A172TAY3_9DEIO/546-702 ..ehldaa------HLS...PTPRLDPKQAMQHLKS...GASAYAEGVVAEYLGGNVPGLTLTRPGDPHPGG..ELILYALPTESDLRMWV......TAG..RVAFAFGPKTLAELEGAL..TRHH....LAPPPPNPLLD...............ATQDDa.......hLESAADAYRRWQWAHHHRTLNDDGWTASVHAMLGLEVPE......
A0A0F7JL70_9DEIO/537-694 .......l-DAPTPER-...PTPRLNPKAAMEHLRA...GASAYAEGPVAAYLRDNVPGLTLVTTADAHPGG..ELILYALPPEDTLRGWLyatgtrPAA..SLAFAFGPKTLAELEGSL..SRHH....LSAPPANPLLN...............PGT--.........LEAAADAYRRWQWAHHWRTLSDDGWTASVHAMLGEPVQE......
C1D146_DEIDV/542-696 ........LEGVTAAGP...HLARLNPKAAMEHLRA...GASAFADGAVAAYLRDNVPGLTLVQPGEAHPGG..ELILYALPPEADLRLWL......SSG..KVAFAFGPKTLAELEGSL..TRHH....LSPPQVTPLTG...............VDSAQ.........MEWAADAYRNWQWAHHHRTLDDASWTASVYAMLGLPVP-e.....
A0A2K3V293_9DEIO/517-672 ....ldvs-----ESGA...SVPRLQPQGAMEHLRA...GASAYALGPVAAYLKDNVPGLTLVEGGEAHPGG..ELILYALPAEDDLRRWL......ADG..RVAFAFGPKTLSELEGAL..TRHH....LAAPPPNPLQD...............ATLDDp.......hMEAAADAYRRWQWAHHHKVLDDAGWSASVYAMLGLPA--la....
A0A2Z3JI86_9DEIO/515-665 ........LAGDAGNGP...VLERLDPKTAMGHLRT...GAAAYATAEVAEYLQGNIPGLSLLGPGDDLGG-..EVVLYGLPPEDSLRRWL......KQG..RVAFAWGPKTLGELEG--..--HS....LGRRSVLSGLD...............YAQAG........vREQAADTYRRFQWSHLYRMLDDEGFTRAVQAMLGLQAG-e.....
#=GC seq_cons .............ssss...slPRLsP+pAMs+L+A...GAuAYApGsVAsYLccNVPGLpLlpsG-saPGs..ELILYALPsEsDLRRWL......ssG..+VAFAaGPKTLuELEGuh..sha+....Lusssssslhs...............h...p.........hEpAADAYRRWQWAHhYRsLDDuGWouuVpAMLGLss..t.....
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