#=GF ID RepA1_leader
#=GF AC PF08048.16
#=GF DE Tap RepA1 leader peptide
#=GF AU Lee SC;0000-0002-0504-0859
#=GF AU Rossi R;
#=GF SE Short protein clustering
#=GF GA 25.00 25.00;
#=GF TC 28.80 38.00;
#=GF NC 22.30 18.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 1447133
#=GF RT Expression of the repA1 gene of IncFII plasmid NR1 is
#=GF RT translationally coupled to expression of an overlapping leader
#=GF RT peptide.
#=GF RA Wu R, Wang X, Womble DD, Rownd RH;
#=GF RL J Bacteriol 1992;174:7620-7628.
#=GF DR INTERPRO; IPR012605;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of the RepA1 leader peptides. The
#=GF CC frequency of replication of IncFII plasmid NR1 during the cell
#=GF CC division cycle is regulated by the control of the synthesis of
#=GF CC the plasmid-specific replication initiation protein (RepA1).
#=GF CC When RepA1 is synthesised, it binds to the plasmid replication
#=GF CC origin (ori) and effects the assembly of a replication complex
#=GF CC composed of host proteins that mediate the replication of the
#=GF CC plasmid [1]. The tap gene encodes a 24-amino acids protein. The
#=GF CC translation of tap is required for translation of repA.
#=GF SQ 9
#=GS D2TV78_CITRI/1-24 AC D2TV78.1
#=GS A0A7Y7BBH6_STRMO/1-24 AC A0A7Y7BBH6.1
#=GS Q7ARH6_YERPE/1-24 AC Q7ARH6.1
#=GS A0A6I4VDG9_9GAMM/1-23 AC A0A6I4VDG9.1
#=GS A0A7X3M1E0_9GAMM/1-24 AC A0A7X3M1E0.1
#=GS Q7DAR1_SALTY/1-25 AC Q7DAR1.1
#=GS A0A2J5A2F2_9ENTR/1-25 AC A0A2J5A2F2.1
#=GS REPL_SHIFL/1-24 AC P62551.1
#=GS A0A249WS99_9ENTR/1-25 AC A0A249WS99.1
D2TV78_CITRI/1-24 MPGKVQDFFLCSLLLR-IVSAGWCD
A0A7Y7BBH6_STRMO/1-24 MPGKVQDFFLCSLLL-CNISAGWCD
Q7ARH6_YERPE/1-24 MFRKVQYL-LRLLLLPCNISAGRCD
A0A6I4VDG9_9GAMM/1-23 MPRKLQYI-LCLLL-LCIVSAGRRD
A0A7X3M1E0_9GAMM/1-24 MLRKVQYF-LYTLLLLCNKSAGKRD
Q7DAR1_SALTY/1-25 MLRKFQYLFLWHLLLPCIVSAGRSD
A0A2J5A2F2_9ENTR/1-25 MLRKLQAQFLCHSLLLCNISAGSGD
REPL_SHIFL/1-24 MPGKVQDFFLCSLLLR-IVSAGWCD
A0A249WS99_9ENTR/1-25 MLRKLQYPFLCHLLLPCNISAGWCD
#=GC seq_cons M.RKlQhhFLCpLLL.C.lSAGhsD
//
