#=GF ID Rho_Binding
#=GF AC PF08912.15
#=GF DE Rho Binding
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE pdb_1s1c
#=GF GA 23.00 23.00;
#=GF TC 23.00 23.00;
#=GF NC 22.90 22.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Coiled-coil
#=GF RN [1]
#=GF RM 14660612
#=GF RT Structural insights into the interaction of ROCKI with the
#=GF RT switch regions of RhoA.
#=GF RA Dvorsky R, Blumenstein L, Vetter IR, Ahmadian MR;
#=GF RL J Biol Chem. 2004;279:7098-7104.
#=GF DR INTERPRO; IPR015008;
#=GF DR SO; 0001080; coiled_coil;
#=GF CC Rho Binding Domain is responsible for the recognition and
#=GF CC binding of Rho binding domain-containing proteins (such as ROCK)
#=GF CC to Rho, resulting in activation of the GTPase which in turn
#=GF CC modulates the phosphorylation of various signalling proteins.
#=GF CC This domain is within an amphipathic alpha-helical coiled-coil
#=GF CC and interacts with Rho through predominantly hydrophobic
#=GF CC interactions [1].
#=GF SQ 2791
#=GS A0A2J7PRH3_9NEOP/551-615 AC A0A2J7PRH3.1
#=GS A0A7L0D2M1_9CHAR/927-995 AC A0A7L0D2M1.1
#=GS A0A8C5TWP4_9PASS/950-1016 AC A0A8C5TWP4.1
#=GS A0A8C5WT19_LATLA/940-1008 AC A0A8C5WT19.1
#=GS A0A5C6NW41_9TELE/961-1018 AC A0A5C6NW41.1
#=GS A0A2Y9KC77_ENHLU/978-1046 AC A0A2Y9KC77.1
#=GS A0A5N4CHT9_CAMDR/875-941 AC A0A5N4CHT9.1
#=GS A0A8C8JKS0_ONCTS/883-942 AC A0A8C8JKS0.1
#=GS A0A672HQG8_SALFA/667-735 AC A0A672HQG8.1
#=GS A0A8C0LMA3_CANLU/855-904 AC A0A8C0LMA3.1
#=GS A0A671LKL7_9TELE/773-865 AC A0A671LKL7.1
#=GS A0A8C1AGZ1_CYPCA/866-883 AC A0A8C1AGZ1.1
#=GS A0A671LG25_9TELE/936-1002 AC A0A671LG25.1
#=GS A0A8C6T3G1_9GOBI/934-999 AC A0A8C6T3G1.1
#=GS A0A3P8WZ32_CYNSE/888-952 AC A0A3P8WZ32.1
#=GS A0A7M4F748_CROPO/983-999 AC A0A7M4F748.1
#=GS A0A8V0XE48_CHICK/981-1049 AC A0A8V0XE48.1
#=GS A0A8C9ZJR4_SANLU/917-978 AC A0A8C9ZJR4.1
#=GS A0A8C5GTF9_9TELE/699-776 AC A0A8C5GTF9.1
#=GS A0A674EPE8_SALTR/953-997 AC A0A674EPE8.1
#=GS A0A8B7ZH61_ACAPL/949-1017 AC A0A8B7ZH61.1
#=GS A0A7N9AXA9_9TELE/938-955 AC A0A7N9AXA9.1
#=GS A0A7L1KVF9_HIMHI/937-1005 AC A0A7L1KVF9.1
#=GS ROCK1_BOVIN/355-421 AC Q8MIT6.1
#=GS A0A1S3JQ27_LINUN/755-822 AC A0A1S3JQ27.1
#=GS A0A8C4CAB5_9TELE/880-946 AC A0A8C4CAB5.1
#=GS A0A7M7JEF2_VARDE/877-939 AC A0A7M7JEF2.1
#=GS A0A8C4AJ19_9TELE/909-975 AC A0A8C4AJ19.1
#=GS A0A7L3N2P4_9AVES/931-999 AC A0A7L3N2P4.1
#=GS A0A673GCK4_9TELE/934-1002 AC A0A673GCK4.1
#=GS T1HUL2_RHOPR/945-1009 AC T1HUL2.1
#=GS A0A7M7M965_VARDE/968-1031 AC A0A7M7M965.1
#=GS A0A8C8SJ61_9SAUR/980-1048 AC A0A8C8SJ61.1
#=GS A0A4W4HJ54_ELEEL/948-1016 AC A0A4W4HJ54.1
#=GS A0A484CQ27_PERFV/955-1021 AC A0A484CQ27.1
#=GS A0A672GKX3_SALFA/950-1016 AC A0A672GKX3.1
#=GS A0A8C0EYX7_BUBBB/836-902 AC A0A8C0EYX7.1
#=GS A0A8C0ULJ7_CYACU/1000-1068 AC A0A8C0ULJ7.1
#=GS A0A7K5ZXS2_ONYCO/928-996 AC A0A7K5ZXS2.1
#=GS A0A7K8DM08_9CORV/951-1019 AC A0A7K8DM08.1
#=GS A0A8C5AEK4_GADMO/946-1011 AC A0A8C5AEK4.1
#=GS A0A8C4C7Q6_9TELE/936-1004 AC A0A8C4C7Q6.1
#=GS A0A6I9ZTY7_ACIJB/978-1046 AC A0A6I9ZTY7.1
#=GS A0A8D0FQZ3_STROC/949-1015 AC A0A8D0FQZ3.1
#=GS A0A6J3B7G0_VICPA/994-1062 AC A0A6J3B7G0.1
#=GS A0A672SX20_SINGR/755-818 AC A0A672SX20.1
#=GS A0A8C9ALP6_PROSS/948-1014 AC A0A8C9ALP6.1
#=GS H3B7E7_LATCH/973-1041 AC H3B7E7.1
#=GS A0A4W6FC72_LATCA/913-961 AC A0A4W6FC72.1
#=GS A0A8V8TL90_HUMAN/415-483 AC A0A8V8TL90.1
#=GS A0A2K6FCX1_PROCO/951-1019 AC A0A2K6FCX1.1
#=GS A0A8K0JV16_LADFU/18-82 AC A0A8K0JV16.1
#=GS A0A671EIM0_RHIFE/293-361 AC A0A671EIM0.1
#=GS A0A8C8JQ84_ONCTS/965-1010 AC A0A8C8JQ84.1
#=GS O73732_XENLA/966-1034 AC O73732.1
#=GS A0A8C6NS80_NOTFU/549-604 AC A0A8C6NS80.1
#=GS G1RV80_NOMLE/974-1042 AC G1RV80.2
#=GS A0A3P8U321_AMPPE/971-1039 AC A0A3P8U321.1
#=GS A0A670YDH8_PSETE/946-979 AC A0A670YDH8.1
#=GS I3N5C1_ICTTR/948-1014 AC I3N5C1.2
#=GS G3TF10_LOXAF/948-1014 AC G3TF10.1
#=GS A0A8C4H4F2_DICLA/971-1039 AC A0A8C4H4F2.1
#=GS A0A7N8YM67_9TELE/853-921 AC A0A7N8YM67.1
#=GS A0A8C0LS61_CANLU/884-952 AC A0A8C0LS61.1
#=GS A0A5E4NFR8_9HEMI/534-596 AC A0A5E4NFR8.1
#=GS A0A665W5R3_ECHNA/717-787 AC A0A665W5R3.1
#=GS A0A3B1ICK4_ASTMX/896-964 AC A0A3B1ICK4.1
#=GS A0A8C1AIM3_CYPCA/740-816 AC A0A8C1AIM3.1
#=GS A0A673JJ56_9TELE/894-962 AC A0A673JJ56.1
#=GS K7FM57_PELSI/950-1016 AC K7FM57.1
#=GS A0A8M9PSI1_DANRE/966-1034 AC A0A8M9PSI1.1
#=GS D3ZN37_RAT/867-933 AC D3ZN37.3
#=GS A0A8C4ZD01_GADMO/952-1017 AC A0A8C4ZD01.1
#=GS A0A7F8QSC3_LEPWE/947-1013 AC A0A7F8QSC3.1
#=GS A0A665W4V8_ECHNA/923-989 AC A0A665W4V8.1
#=GS M3WUL5_FELCA/892-960 AC M3WUL5.4
#=GS A0A8B7ZCM2_ACAPL/949-1017 AC A0A8B7ZCM2.1
#=GS A0A851KE95_VIDCH/928-996 AC A0A851KE95.1
#=GS A0A674MR45_TAKRU/969-1037 AC A0A674MR45.1
#=GS A0A3B5QR17_XIPMA/916-984 AC A0A3B5QR17.1
#=GS A0A5F8G2A2_MONDO/729-792 AC A0A5F8G2A2.1
#=GS A0A671EFA1_RHIFE/978-1046 AC A0A671EFA1.1
#=GS A0A670Z7N1_PSETE/871-930 AC A0A670Z7N1.1
#=GS A0A8C7BG79_NEOVI/978-1046 AC A0A8C7BG79.1
#=GS A0A7K6CLB1_PTIVI/951-1019 AC A0A7K6CLB1.1
#=GS A0A8C1F5T1_CYPCA/850-918 AC A0A8C1F5T1.1
#=GS A0A8C6U2Z1_9GOBI/978-1048 AC A0A8C6U2Z1.1
#=GS A0A8C0R8J0_CANLU/973-1041 AC A0A8C0R8J0.1
#=GS A0A7K9N1S6_9CORV/927-995 AC A0A7K9N1S6.1
#=GS A0A673YVZ2_SALTR/974-1042 AC A0A673YVZ2.1
#=GS A0A096NJ50_PAPAN/293-361 AC A0A096NJ50.3
#=GS A0A8C1HY88_CYPCA/810-872 AC A0A8C1HY88.1
#=GS A0A6Q2ZG36_ESOLU/825-889 AC A0A6Q2ZG36.1
#=GS F1N319_BOVIN/978-1046 AC F1N319.3
#=GS A0A7L4BWT9_9AVES/733-801 AC A0A7L4BWT9.1
#=GS A0A0Q3R9S9_AMAAE/950-1016 AC A0A0Q3R9S9.1
#=GS A0A671LF79_9TELE/911-977 AC A0A671LF79.1
#=GS A0A4W5PXN0_9TELE/960-1028 AC A0A4W5PXN0.1
#=GS A0A6P9D8W2_PANGU/996-1064 AC A0A6P9D8W2.1
#=GS A0A8C5KI90_JACJA/948-1014 AC A0A8C5KI90.1
#=GS A0A8C5GV72_9TELE/917-983 AC A0A8C5GV72.1
#=GS A0A8C3HKD5_CHRPI/984-1052 AC A0A8C3HKD5.1
#=GS A0A6I8P135_ORNAN/939-1007 AC A0A6I8P135.1
#=GS A0A1S3SQ79_SALSA/967-1035 AC A0A1S3SQ79.1
#=GS A0A8C3TPT4_CATUS/978-1046 AC A0A8C3TPT4.1
#=GS A0A8C8JGR4_ONCTS/932-998 AC A0A8C8JGR4.1
#=GS A0A2K5WB78_MACFA/948-1014 AC A0A2K5WB78.2
#=GS A0A3P9DFT3_9CICH/952-1018 AC A0A3P9DFT3.1
#=GS A0A093HKK8_STRCA/923-989 AC A0A093HKK8.1
#=GS A0A287A705_PIG/748-811 AC A0A287A705.2
#=GS A0A674B4C0_SALTR/918-986 AC A0A674B4C0.1
#=GS A0A6P8IWV1_ACTTE/970-1038 AC A0A6P8IWV1.1
#=GS A0A671WC41_SPAAU/856-873 AC A0A671WC41.1
#=GS A0A8C8BR49_9STRI/950-1016 AC A0A8C8BR49.1
#=GS A0A6Q2ZKC4_ESOLU/975-1043 AC A0A6Q2ZKC4.1
#=GS A0A2K6E498_MACNE/978-1046 AC A0A2K6E498.1
#=GS A0A6J2V5G7_CHACN/964-1032 AC A0A6J2V5G7.1
#=GS A0A8J0R1I4_XENTR/964-1032 AC A0A8J0R1I4.1
#=GS A0A6J3BGA4_VICPA/947-1013 AC A0A6J3BGA4.1
#=GS A0A668TN73_OREAU/816-882 AC A0A668TN73.1
#=GS A0A673K5E2_9TELE/907-967 AC A0A673K5E2.1
#=GS A0A6P5A6F0_BRABE/1000-1068 AC A0A6P5A6F0.1
#=GS A0A2K6N4H1_RHIBE/978-1046 AC A0A2K6N4H1.1
#=GS A0A087V3E3_BALRE/919-985 AC A0A087V3E3.1
#=GS A0A6P8VW30_GYMAC/956-1022 AC A0A6P8VW30.1
#=GS A0A672L107_SINGR/857-923 AC A0A672L107.1
#=GS A0A3Q7QAB5_CALUR/948-1014 AC A0A3Q7QAB5.1
#=GS A0A8C8JLK4_ONCTS/922-988 AC A0A8C8JLK4.1
#=GS A0A8C2TIL4_COTJA/934-1002 AC A0A8C2TIL4.1
#=GS F6SWC6_ORNAN/950-1016 AC F6SWC6.3
#=GS A0A0M4ETS1_DROBS/980-1045 AC A0A0M4ETS1.1
#=GS A0A8C4EU45_DICLA/939-1005 AC A0A8C4EU45.1
#=GS A0A6P9D6Y4_PANGU/990-1058 AC A0A6P9D6Y4.1
#=GS A0A8C6V8F3_9GOBI/894-966 AC A0A8C6V8F3.1
#=GS A0A8C3CFF4_CAIMO/986-1054 AC A0A8C3CFF4.1
#=GS A0A6P3X5T3_DINQU/942-1006 AC A0A6P3X5T3.1
#=GS A0A8C7NB52_ONCKI/889-955 AC A0A8C7NB52.1
#=GS A0A8V5FRD5_MELUD/978-1046 AC A0A8V5FRD5.1
#=GS A0A7K6CXA8_9PASS/928-996 AC A0A7K6CXA8.1
#=GS A0A8B7JKR6_9AVES/889-957 AC A0A8B7JKR6.1
#=GS A0A2K6E4B0_MACNE/974-1042 AC A0A2K6E4B0.1
#=GS A0A3B1JCM3_ASTMX/892-960 AC A0A3B1JCM3.1
#=GS A0A093RNB9_PYGAD/923-989 AC A0A093RNB9.1
#=GS A0A8C5X9J8_9PASS/948-1016 AC A0A8C5X9J8.1
#=GS A0A4W5QQE1_9TELE/881-896 AC A0A4W5QQE1.1
#=GS A0A0A0AL22_CHAVO/924-990 AC A0A0A0AL22.1
#=GS A0A3Q1ATV6_AMPOC/921-987 AC A0A3Q1ATV6.1
#=GS A0A8C4CEF1_9TELE/913-974 AC A0A8C4CEF1.1
#=GS A0A2K5Y2J1_MANLE/954-1022 AC A0A2K5Y2J1.1
#=GS H2RCA0_PANTR/974-1042 AC H2RCA0.2
#=GS A0A671EES2_RHIFE/978-1046 AC A0A671EES2.1
#=GS A0A674MSK9_TAKRU/940-1006 AC A0A674MSK9.1
#=GS A0A8B8Z329_BALMU/984-1052 AC A0A8B8Z329.1
#=GS A0A673A421_9TELE/954-1020 AC A0A673A421.1
#=GS A0A8C5B8N6_GADMO/963-1031 AC A0A8C5B8N6.1
#=GS A0A0D9R4P6_CHLSB/973-1041 AC A0A0D9R4P6.1
#=GS G3PH51_GASAC/962-1030 AC G3PH51.1
#=GS A0A6P4FGN7_DRORH/962-1027 AC A0A6P4FGN7.1
#=GS A0A8C5IJH0_JUNHY/950-1016 AC A0A8C5IJH0.1
#=GS A0A6J2V7L0_CHACN/958-1026 AC A0A6J2V7L0.1
#=GS A0A671XT94_SPAAU/977-1045 AC A0A671XT94.1
#=GS A0A8C2XKG9_CYCLU/955-1023 AC A0A8C2XKG9.1
#=GS A0A158PQ70_BRUPA/2134-2204 AC A0A158PQ70.1
#=GS A0A2K5Q381_CEBIM/948-1014 AC A0A2K5Q381.1
#=GS A0A4X2KMK5_VOMUR/891-956 AC A0A4X2KMK5.1
#=GS A0A0V0RV33_9BILA/930-998 AC A0A0V0RV33.1
#=GS A0A7L1RWF2_9PASS/951-1019 AC A0A7L1RWF2.1
#=GS A0A1J1HSG0_9DIPT/960-1024 AC A0A1J1HSG0.1
#=GS A0A7N8Y5H3_9TELE/964-1032 AC A0A7N8Y5H3.1
#=GS A0A452RZ42_URSAM/871-939 AC A0A452RZ42.1
#=GS A0A8C8F5J2_ONCTS/919-987 AC A0A8C8F5J2.1
#=GS A0A7J7EUE5_DICBM/948-1014 AC A0A7J7EUE5.1
#=GS A0A7E6CDQ2_9CHIR/947-1013 AC A0A7E6CDQ2.1
#=GS A0A7K7T6U3_9TYRA/928-996 AC A0A7K7T6U3.1
#=GS A0A7N8XCG1_9TELE/922-955 AC A0A7N8XCG1.1
#=GS A0A8C5EMC0_9TELE/924-988 AC A0A8C5EMC0.1
#=GS A0A8C0ICI4_BUBBB/950-1016 AC A0A8C0ICI4.1
#=GS A0A674B3B0_SALTR/933-1001 AC A0A674B3B0.1
#=GS A0A553QA57_9TELE/970-1038 AC A0A553QA57.1
#=GS A0A6A4WYY5_AMPAM/944-1009 AC A0A6A4WYY5.1
#=GS A0A060VUS1_ONCMY/971-1041 AC A0A060VUS1.1
#=GS A0A4W5PTY1_9TELE/963-1031 AC A0A4W5PTY1.1
#=GS A0A811YHS9_NYCPR/978-1046 AC A0A811YHS9.1
#=GS A0A7K9CFB6_9PICI/927-995 AC A0A7K9CFB6.1
#=GS A0A670HVL9_PODMU/991-1059 AC A0A670HVL9.1
#=GS A0A8C5EMB9_9TELE/920-984 AC A0A8C5EMB9.1
#=GS A0A6P5CJK2_BOSIN/892-960 AC A0A6P5CJK2.1
#=GS A0A673A1Q1_9TELE/816-882 AC A0A673A1Q1.1
#=GS A0A7N6BQF1_ANATE/946-1007 AC A0A7N6BQF1.1
#=GS A0A226N659_CALSU/923-991 AC A0A226N659.1
#=GS A0A673YXP6_SALTR/974-1042 AC A0A673YXP6.1
#=GS A0A672P2M9_SINGR/972-1040 AC A0A672P2M9.1
#=GS A0A4Z2G6Y1_9TELE/947-1015 AC A0A4Z2G6Y1.1
#=GS E4WRQ2_OIKDI/5-49 AC E4WRQ2.1
#=GS A0A553R9F5_9TELE/543-610 AC A0A553R9F5.1
#=GS A0A8C3TL97_CHESE/934-1003 AC A0A8C3TL97.1
#=GS H2VBN2_TAKRU/906-974 AC H2VBN2.3
#=GS A0A8B9NUV8_9AVES/730-794 AC A0A8B9NUV8.1
#=GS A0A663EYH0_AQUCH/978-1046 AC A0A663EYH0.1
#=GS D1W0H5_9BACT/1-57 AC D1W0H5.1
#=GS A0A6J2AZV6_ACIJB/978-1046 AC A0A6J2AZV6.1
#=GS A0A8C3T556_CHESE/941-958 AC A0A8C3T556.1
#=GS A0A8C7LHT2_ONCKI/710-725 AC A0A8C7LHT2.1
#=GS A0A8C6WL00_9GOBI/834-893 AC A0A8C6WL00.1
#=GS A0A8C8MHT4_ONCTS/710-780 AC A0A8C8MHT4.1
#=GS A0A4V6AP69_COLLU/971-1039 AC A0A4V6AP69.1
#=GS A0A8C4NWL2_DICLA/956-1008 AC A0A8C4NWL2.1
#=GS A0A8C0UJC2_CYACU/978-1046 AC A0A8C0UJC2.1
#=GS A0A672Q6S1_SINGR/959-1027 AC A0A672Q6S1.1
#=GS A0A662YT72_ACIRT/899-965 AC A0A662YT72.1
#=GS A0A4W4H5K9_ELEEL/298-366 AC A0A4W4H5K9.1
#=GS G1LJU4_AILME/948-1014 AC G1LJU4.2
#=GS A0A7K4UU06_9EMBE/928-996 AC A0A7K4UU06.1
#=GS A0A8C7YMG7_9TELE/933-999 AC A0A8C7YMG7.1
#=GS G3SZH5_LOXAF/979-1047 AC G3SZH5.1
#=GS H2UA39_TAKRU/956-1022 AC H2UA39.3
#=GS A0A7R8Z1U4_HERIL/912-976 AC A0A7R8Z1U4.1
#=GS A0A3Q1F291_9TELE/971-1039 AC A0A3Q1F291.1
#=GS A0A3P8W5A4_CYNSE/950-1016 AC A0A3P8W5A4.1
#=GS A0A7L4HQG6_SCOUM/738-806 AC A0A7L4HQG6.1
#=GS A0A0V1LF45_9BILA/918-986 AC A0A0V1LF45.1
#=GS A0A665W5C7_ECHNA/901-969 AC A0A665W5C7.1
#=GS A0A4W6C714_LATCA/955-1021 AC A0A4W6C714.1
#=GS A0A8C4H4Z3_DICLA/971-1039 AC A0A8C4H4Z3.2
#=GS A0A1U7S2B7_ALLSI/950-1016 AC A0A1U7S2B7.1
#=GS A0A6F9C2F5_9TELE/111-145 AC A0A6F9C2F5.1
#=GS A0A455BYE7_PHYMC/978-1046 AC A0A455BYE7.1
#=GS G1PP69_MYOLU/950-1016 AC G1PP69.1
#=GS A0A8D0GSM0_SPHPU/950-1016 AC A0A8D0GSM0.1
#=GS A0A0V0Y8Q8_TRIPS/929-997 AC A0A0V0Y8Q8.1
#=GS A0A8C3T5G1_CHESE/689-757 AC A0A8C3T5G1.1
#=GS A0A3Q3G5A9_9LABR/971-1039 AC A0A3Q3G5A9.1
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A0A2K5DKR3_AOTNA/974-1042 ...............................LTSDVANLANEKEELNNKL....KDVQE..Q.LSRLK...D................................EEISAAAIKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A452IQK1_9SAUR/984-1052 ...............................LTSDVANLANEKEELNNKL....KEVQE..Q.IARLK...E................................EETNTTIIKT...QFEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A8C0BQS8_9AVES/859-909 ...........................lnyl-------------------....---AT..E.ITKLK...E................................EEANVGNIKA...QFEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-g....
A0A7K6XJF6_9PASE/928-996 ...............................LTSDVANLANEKEELNNKL....KEAQE..Q.ITKLK...E................................EEANVGNIKA...QFEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-g....
A0A8C5QNN1_9ANUR/939-1007 ...............................LTIDVGNLANEKEELNNKV....KEGYE..Q.IQRLR...E................................EETTVIVIKS...QFEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-i....
A0A2U4C0C9_TURTR/978-1046 ...............................LTSDVANLANEKEELNNKW....KDAQE..Q.LSRLK...D................................EEISAAAIKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
G1KHH5_ANOCA/950-1016 ...............................LTKDVAFLTKENSELNEKV....KKLEE..D.YKLKT...-................................-EEEISIIRM...QYEKNLN......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
U3I4S8_ANAPP/950-1016 ...............................LTKDVDLITKENSEISEKI....RKQEE..E.YKIKK...-................................-EEEINNIRM...QYEKSIN......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A3P7DL67_WUCBA/2052-2122 ............................daa----IQLISQKEEELQQSL....QGAQN..E.LRSIS...Erdw.........................srasPEESIRDLK-...---NQLE......H...........EK.V.....M........KT.......T....AINKLEEVM.AQR-q....
A0A2U4AZ74_TURTR/947-1013 ...............................LTKDIELLRKENEELTDKM....RKAEE..E.YKLKK...-................................-EEEINNLKA...AFEKNIN......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A1S3R692_SALSA/954-1020 ...............................LTKDVENLSKEKAELNNKL....RIQEE..E.YASQK...-................................-EEITNTIKA...NYEKVLS......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A093DN19_9AVES/690-745 ...............................LTSDVANLANEKEELNNKL....KELQE..Q.ITKLK...E................................EEANVGNIKA...QFEKQLL......N...........ER.T.....L........KT.......Q....---------.----.....
A0A6Q2YB67_ESOLU/971-1039 ...............................LTADVANLANEKEELNDQL....KETQQ..L.LQRAR...E................................DVMEMNSMKT...SFEKQLQ......T...........ER.T.....L........KI.......Q....AVNKLAEVM.NRRE.....
A0A673ZC44_SALTR/965-1011 ...........................pfsa-------------------....-----..E.YDSQ-...-................................KEEITNTIKA...NYEKVLS......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A6P7SQ41_OCTVU/947-1012 ..............................g--KNNEQLQNEKDELINRM....NKMAD..D.LKNEK...-................................SENNISELE-...QLRKLLQ......D...........ER.L.....K........KI.......Q....AVNKLAEVM.NRKE.....
A0A8C1ADJ0_CYPCA/881-947 ...............................LTKDAEILSKEKAELNERL....QAREE..E.FAAAK...-................................-EELASTVKA...NYEKALN......I...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A2K5Y2I4_MANLE/959-1027 ...............................LTSDVANLANEKEELNNKL....KDVQE..Q.LSRLK...D................................EEISAAAIKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A8C4LIJ2_EQUAS/906-972 ...............................LTSDVANLANEKEELNNKL....KDAQE..R.KLKD-...-................................EEISAAAIKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A1D1VMX7_RAMVA/933-1007 .............................he--RNVQDLIQQREEMERRL....NAAVS..E.IKKER...Ppvagm......................ngygdDG----PVVI...QLRRQLE......Q...........EQ.V.....K........KQ.......Q....AVNKLAEVM.QQ--rs...
A0A094MFE4_ANTCR/914-980 ...............................LTKDVDLITKENSEISEKI....KKQEE..E.YKIKN...-................................-EEEINNIRM...HYEKSIN......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A8C3AQA6_CYCLU/922-990 ...............................LTVDVANLASEKEELNNQL....KNMQQ..Q.LQKAK...E................................EEKQMNSLKL...SFEKLLQ......N...........ER.T.....L........KI.......Q....AINKLAEVM.NRRE.....
A0A8C8M6E4_ONCTS/896-962 ...............................LTKDVENLSKEKAELDHKL....RTQKE..E.YDSQK...-................................-EEITNTIKA...NYEKVLS......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A8N1S8I6_9HYME/942-1006 ..............................f-KKSVDQALKEKEDLSKRY....KELQD..Q.LGKAQ...S................................NVEEIEKLS-...---SKLK......T...........EQ.L.....L........KQ.......Q....AVNKLAEIM.NRKD.....
A0A5C6NP68_9TELE/1055-1123 ...............................LTVDVANLAGEKEELNNQL....KEMQQ..K.LQKAK...E................................AEKQMNSHKM...SFERMLQ......N...........ER.T.....L........KI.......Q....AINKLAEVM.NRR-v....
A0A8B6GV58_MYTGA/948-1015 .............................ys--KKVEQIQMEKDDIVNRM....KSLQD..D.YQNMQ...Qk.............................svPDNELDKIK-...---KSLE......E...........ER.M.....K........KI.......Q....AVNKLAEIM.NRKE.....
A0A4W5MM06_9TELE/850-918 ...............................LTVDVANLANEKEELNNQL....KEMQQ..Q.LQMAR...E................................EERHMNSVKM...SFEKNLQ......I...........EK.T.....L........KI.......Q....AVNKLSEIM.NRRE.....
A0A6P4JNH7_DROKI/958-1023 ...............................LHKKLGQKAVECEDLVQQH....KKQQE..D.LAQLR..gS................................KDEEIAKLQ-...---EKCK......N...........EV.L.....L........KQ.......V....AVNKLAEVM.NRRD.....
A0A8C4VXP9_9SAUR/950-1016 ...............................LTNDVEFLTKENAELIEKN....KKQEE..E.FKLKK...-................................-EEEINNIRM...HYEKNLQ......T...........ER.T.....L........KI.......Q....AVNKLAEIM.NRKD.....
A0A8C8JH74_ONCTS/915-983 ...............................LTSDVANLANEKEELNNKL....RETLE..E.LQTSK...D................................DEQQMSQMKL...MFEKHLQ......S...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A3Q2WU81_HAPBU/925-990 ...............................LTVDVANLASEKEELNNQL....KEMQQ..K.LQKAK...-................................--DEENYFKE...SFDKQLC......N...........ER.T.....L........KI.......Q....AVNKLAEVM.NRRE.....
A0A8J6GX09_MICOH/802-870 ...............................LTSDVANLANEKEELNNKL....KDTQE..Q.LSKLK...D................................EEISAAAIKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A2I4BTR4_9TELE/968-1036 ...............................LTVDVANLASEKEELNNKL....KELQQ..E.LQKAK...E................................EEKHLNSVKV...SFEKQLQ......Y...........ER.T.....L........KI.......Q....AVNKLAEVM.NRKE.....
A0A5C6NW41_9TELE/1035-1058 ......................tkqslthic-------------------....-----..-.-----...-................................----------...-------......-...........--.-.....-........-L.......Q....AVNKLAEIM.NRKE.....
A0A6P4ZPV8_BRABE/998-1066 ..............................l-SASLEQMKAERDDMNNRL....KKAVE..D.LNNKD...E................................LSQALNEQKA...HYEKQLL......K...........EK.E.....L........KI.......Q....AINKLAQIV.NSKE.....
A0A6I8PHX3_ORNAN/936-1004 ...............................LTSDVANLANEKEELNNKA....KEIQE..Q.ISRLK...D................................EETSVSIIKA...QYEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A669CIW0_ORENI/864-932 ...............................LTSDVANLANEKEELNNKL....KEAIE..E.TEKSK...D................................WEQQISQMKQ...AFEKQLQ......C...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A3Q1I6E4_ANATE/954-1023 ...............................LTSDVANLANEKEELNNKL....KEAME..G.ISNTS..kD................................WEQQISQMKL...TFEKQLQ......S...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A3B0K1D1_DROGU/950-1015 ...............................LHKKLGQKANEYEDLVQQH....KKQQD..E.LGQLC..vT................................KDEEISKLV-...---EKCK......T...........EV.L.....L........KQ.......V....AVNKLAEVM.HRRD.....
A0A670HVI6_PODMU/904-972 ...............................LTSDVANLANEKEELNNKL....KEVLE..R.MSQMN...A................................EENDIGVLKS...QYEKQLA......Y...........ER.T.....M........KT.......Q....AVNKLAEVM.NRK-n....
A0A2K5DKQ0_AOTNA/978-1046 ...............................LTSDVANLANEKEELNNKL....KDVQE..Q.LSRLK...D................................EEISAAAIKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKE.....
A0A6J2MQP7_9CHIR/948-1014 ...............................LTKDIELLKKENEELTDKM....RKAEE..D.YKLKK...-................................-EEEISNLKA...AYEKNIN......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A8C8CIK5_ONCTS/807-868 ...............................LTVDWANLANEKEELNNTT....EG---..D.AATLK...-................................---YILQCAV...HYHNILW......T...........VY.V.....H........AH.......Q....AINKLAEIM.NRRE.....
A0A7M4F8R2_CROPO/930-946 .............................fn-------------------....-----..-.-----...-................................----------...-------......-...........--.-.....-........-R.......D....AVNKLAEIM.NRKD.....
A0A8C0BQP5_9AVES/731-799 ...............................LTSDVANLANEKEELNNKL....KEAQE..Q.ITKLK...E................................EEANVGNIKA...QFEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-g....
A0A672IIJ1_SALFA/935-1002 ...............................LTVDVANLAGEKEELNNQL....KDMQQ..Q.LQKAK...E................................EEKNMDSIKV...SFEKQLQ......N...........ER.T.....L........KI.......Q....AVNKLHEVI.NR--t....
A0A2K6CYT9_MACNE/948-1014 ...............................LTKDMEILRRENEELTEKM....KKAEE..E.YKLEK...-................................-EEEISNLKA...AFEKNIN......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRKD.....
A0A8B8Q0A2_9MYRT/555-621 ..........................lhere-----ESLIKQLEETNKEM....AYRLE..E.IKTEL..eN................................RDEKVELLQ-...---RQLH......Q...........ER.L.....L........KG.......Q...aAVNKLAEIM.YRKD.....
A0A8J0VDB1_XENLA/965-1033 ...............................LTIDVGNLANEKEDLNNKL....KESQE..Q.IQKLK...E................................EESSIVTVKA...QFEKQLL......T...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-l....
A0A7K7AJD1_9AVES/931-999 ...............................LTSDVANLANEKEELNNKL....KEVQE..Q.ITKLK...E................................EEANIGNIKA...QFEKQLL......N...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-g....
#=GC seq_cons ...............................LTpDVsNLupEKEELNsKL....KctpE..p.hpphK.....................................EpphsslKh...paEKpLp......s...........ER.T.....L........KT.......Q....AVNKLAEIM.NRK-.....
//
