#=GF ID   Ribonucleas_3_2
#=GF AC   PF11469.12
#=GF DE   Ribonuclease III
#=GF PI   DUF3204;
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   pdb_1ztd
#=GF GA   25.00 25.00;
#=GF TC   26.00 61.20;
#=GF NC   23.80 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0539
#=GF DR   INTERPRO; IPR021568;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of archaeal ribonuclease_III proteins.
#=GF SQ   16
#=GS A0A133VAB8_9EURY/8-126   AC A0A133VAB8.1
#=GS S5ZK89_9CREN/17-123      AC S5ZK89.1
#=GS Q8U363_PYRFU/5-122       AC Q8U363.1
#=GS A0A5B9D5J0_9ARCH/25-143  AC A0A5B9D5J0.1
#=GS C6A1R6_THESM/11-129      AC C6A1R6.1
#=GS A0A0F7FIV4_9CREN/1-99    AC A0A0F7FIV4.1
#=GS A0A2U0S3X1_9ARCH/18-114  AC A0A2U0S3X1.1
#=GS A0A133UC09_9EURY/18-137  AC A0A133UC09.1
#=GS A1RX42_THEPD/16-123      AC A1RX42.1
#=GS A0A133V2Z2_9EURY/19-138  AC A0A133V2Z2.1
#=GS A0A133UV83_9EURY/19-138  AC A0A133UV83.1
#=GS F0LJJ7_THEBM/13-131      AC F0LJJ7.1
#=GS A0A8J8C357_9EURY/5-120   AC A0A8J8C357.1
#=GS Q5JE89_THEKO/13-131      AC Q5JE89.1
#=GS A0A133VFN7_9EURY/19-138  AC A0A133VFN7.1
#=GS A0A7L9FEP3_9CREN/1-98    AC A0A7L9FEP3.1
A0A133VAB8_9EURY/8-126              ...p-DLAKLGDVLVNFIYSLGRSIARGQPDGDKIPNSVLAAALVDADLRDLAPSRVDRHQIGDVVEAILAYAWLQEDIEISRAAEVLASSL--.EGVDFQDRD..EVL...N----------------gaeegfknlllkiadres....
S5ZK89_9CREN/17-123                 ....KKLALLGDAIVNFIASAALS-LQKGATGIKVSGKILQSVYSLSILATLD---IEGIDKGEAVEAFLAYAWLNNMFTCEDGVKVVYGSL--.------KKG..KNL...DEALAGLIDKVFK----ehlt..................
Q8U363_PYRFU/5-122                  ....KGLAKFGDSLINFLYSLALTEFLGKPTGDRVPNASLAIALDLTGLSKNLR-RVDKHAKGDYAEALIAKAWLMGLISEREAVEIIKKNLTP.EVLDFSKKK..EAI...GRALAPLLVIISERLTS......................
A0A5B9D5J0_9ARCH/25-143             ....KDLAKFGDTVTNFIYSLAKSVVLGKLDQRKVSRLILSAALKQSDMKKFAKTRSDAHGLADTTEALIGYTYCIGW-SLESMAEVLIETLKNyDLNDFKIEK..LGA...IKAFTHLLLKIKSHL--lt....................
C6A1R6_THESM/11-129                 ....KNLSRFGDSLVNFIFSLALSRYLGYPNAGRVPNASLTIGLEKAGLLHCVPPRTDKHGKGDIAEAIIAYAWFEGEMSIDEAVDILSKNFSS.DITHPSRKK..EVI...GNAFGELLKIIKERLA-l.....................
A0A0F7FIV4_9CREN/1-99               ....---------MVNFVVSAALTLATGKIKGVKVPGKLLNKVYHLSGLSSMRLPY--HVEPGESVESLLGFAWLKNCISCEVAAEIVYSAV--.------KNG..KSI...EEALSILVNEILRR---ca....................
A0A2U0S3X1_9ARCH/18-114             ...q-KLAKLGDAYVNFLYSLALSKKDGEATGIKVKGRLLADAFKKAGLRKFLPSRIDRHKQADAAEALIVYAWIRGTITMEEGLEILEQNE-D.---------..---...-----------------gvealsvl..............
A0A133UC09_9EURY/18-137             ...e-DLAKLGDALANLIYSLARSRARGRPDGAKAPNRVLSGALDKVGLRNLAPSRVDRHRLGDVAEAAIAFAWLEGEVGIEEAAEVVSGPLME.RDFESRRD-..---...-----------------vqegaeegfkellrlvagrlgl
A1RX42_THEPD/16-123                 ....KELARLGDSLVNFLVSAALT-LIGRPTGVKVPGETLARAFLSSRLSKLGKPR--GIAPGEAMEAFLAYAWLKGSLSCEESVEMLYTGL--.------REG..YDV...AQALAKLADYLLEKIEA......................
A0A133V2Z2_9EURY/19-138             ...q-NLAKLGDCLVNLIYSLARSVARETPDGAKAPNRVLSESLNKAGLRDLAPSRSDRHDLGDVAEAIIAYAWLQGKIDIEEAAEILSESFHG.VNFD-NRKKifNAA...EKGFENLLKTIAERIS-f.....................
A0A133UV83_9EURY/19-138             ...q-NLAKLGDCLVNLIYSLARSVARETPDGAKAPNRVLSESLNKAGLRDLAPSRSDRHDLGDVAEAIIAYAWLQGKIDIEEAAEILSESFHG.VNFD-NRKKifNAA...EKGFENLLKTIAERIS-f.....................
F0LJJ7_THEBM/13-131                 ....KNLSKFGDSLVNFIFSLALSEYLGYPSAGRVPNSSLALALERAKLSHLIPPRTDKHGKGDIAEAVIAYAWLEGKITVEEAAEIIKKNLSQ.DVLHFTRKK..EVI...GIAFGELLKVVKERLN-l.....................
A0A8J8C357_9EURY/5-120              qdfk----GFGDALINFLYSLAKSRATGTWTGEKVSNYVLSQALIASDIDSPGG--LDKHEKGDFVESFIAHAWIDHVVTLEEAADVLVGVLKL.YNLEE-DEQ..KAM...VDAFRRLLDHVQEN---hta...................
Q5JE89_THEKO/13-131                 ....KGLAKLGDSLINLVFSLALSEYLGKPTGERVPNASLAIALEMAGLRHIIPPRTDKHGKGDIAEALFAYAWLEKKITIEEAVEILSQNLDD.DVTHFTRKK..ETI...GKAFAVLYEEIGKRLG-l.....................
A0A133VFN7_9EURY/19-138             ...e-NLAKLGDSLVNVIYSLARSIAKGEADGAKVPNKILSDSLSEAGLRELAPTRMSMHELGDVSEAIIAFAWVQGKIEIKEAADILSDSL--.SNVDFENRN..EVMkmsCEGFKDLLLTVSERI--df....................
A0A7L9FEP3_9CREN/1-98               ....----------MNFVVSAALSLASGRAQGEKVPRQTLREAYRLSKLSTTALPY--HCDPAESVEALLGYAWIRKCLSSEFAVELIYNRL--.------SKG..DAL...EKALAFLVDYVLN----scl...................
#=GC seq_cons                       .....sLAKhGDuLVNFlaSLAhShhpGpssGsKVPNplLutALppusLpchsssRhD+HshGDssEAlIAYAWLpGplolEEAsElLtpsL.....hc.p++p..csh...tcAht.Llphlhc+...h.....................
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