#=GF ID   Rotavirus_VP3
#=GF AC   PF06929.15
#=GF DE   Rotavirus VP3 protein
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_14798 (release 10.0)
#=GF GA   27.00 27.00;
#=GF TC   73.70 73.70;
#=GF NC   19.80 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10603323
#=GF RT   Rotavirus open cores catalyze 5'-capping and methylation of
#=GF RT   exogenous RNA: evidence that VP3 is a methyltransferase. 
#=GF RA   Chen D, Luongo CL, Nibert ML, Patton JT; 
#=GF RL   Virology 1999;265:120-130.
#=GF DR   INTERPRO; IPR011181;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several Rotavirus specific VP3 proteins.
#=GF CC   VP3 is known to be a viral guanylyltransferase and is thought to
#=GF CC   posses methyltransferase activity and therefore VP3 is a
#=GF CC   predicted multifunctional capping enzyme [1]. 
#=GF SQ   19
#=GS A0A160NTQ8_9VIRU/1-692    AC A0A160NTQ8.1
#=GS VP3_ROTJ1/194-701         AC Q45UF7.1
#=GS VP3_ROTHC/1-692           AC Q82041.1
#=GS D0TZ85_9VIRU/1-394        AC D0TZ85.1
#=GS L0CSA3_9VIRU/1-683        AC L0CSA3.1
#=GS M4H253_9VIRU/1-690        AC M4H253.1
#=GS A0A0K0LBN7_9VIRU/98-654   AC A0A0K0LBN7.1
#=GS A0A222NY40_9VIRU/1-211    AC A0A222NY40.1
#=GS A0A0D3Q2F6_9VIRU/1-345    AC A0A0D3Q2F6.1
#=GS A0A125RLH0_9VIRU/1-683    AC A0A125RLH0.1
#=GS E7D6N4_9VIRU/1-568        AC E7D6N4.1
#=GS I6WJT2_9VIRU/1-291        AC I6WJT2.1
#=GS E2EBU2_9VIRU/1-681        AC E2EBU2.1
#=GS A0A1L6BXK9_9VIRU/188-702  AC A0A1L6BXK9.1
#=GS K9L4Q7_9VIRU/1-687        AC K9L4Q7.1
#=GS VP3_ROTSH/1-687           AC A2T3S5.1
#=GS A0A1B4XK04_9VIRU/1-687    AC A0A1B4XK04.1
#=GS VP3_ROTS1/1-687           AC P15736.2
#=GS D7NN51_9VIRU/1-687        AC D7NN51.1
A0A160NTQ8_9VIRU/1-692               .................MRVLGLFERGNHLNFADTYIYTWNQQYSYHENAFLISNQVATTIILYLSDAIISEVNKAFELLNSNGIPALIIKT-DHIG.IFTSSNFTYDWQHRIVYFHEYTYYKNNEFIVSDEFWLH-TNINE-LLP-YKLLYYERGLRKLYDGEE--------YILYNTATDDDILYKYIYEKDTIMSGADYLELYEDKNFRNFVHFMRLLRMRFAVPFDQLSNRITRSRAF------FKSKIH.IGLRNESIPQALDNITS.QWINY..S-----ANG-------IMISELKGSG.NYSEKRISEFDIGQFKNYMNFLTLMFYIKNM.-KKRPSC.TIIGAAPGYWIKSMKKY-.-FTIVT..YDDK....KVD-.ST......EHHNRYF.SEED.IAKVRTNGV-YIDVRSD..FDTNDWKKRRKLIEEETKQWLDISYKLLENKYVEAILLKMTAMDIE.IP-DGYFVHFPTTYQRSEYYLLIDRQIIKRQ.KVKVTKSLIYNAIN...TVYSDNVFISGKYSL..RG..KTEG-..VLALYCLSNTINSK...EKVIQYVNSFS.GTCMTVR..LNNTYEVNK.........IIDFKTN......ADYTFLPSDFTCSVSTILTSYRGYAGAFGYAITKDLKSDGNNHIYIIPNARDESNFDTFASHLGLSRYSHSKRFSESATTMSGYLFRDMVSG..KE..DMNNTDKANYA..SGHVFNAI.AHYRFDYTYDIVGWLRLH.KIKQFKVKSDIYEEHTDDEVQNAIEAAYTYYLLDGDRVGKEYAKKIMEIWKI-q...................................................
VP3_ROTJ1/194-701                    ...qsynyrvsrreign--------------------------------------------------------------------------------.-----------------------------------------------------------------------------------------------------------------------------------------LVRDQVF-SLVKGHIHL--.IGPEMESLRNIIMFLHAgNSITF..HTIDTSTKSSYIKE--LEFNKKTKLT.------MASVLVNQRKNMNNFFKGLIRHYIT.YGIPRKV.YYIGAYPSYWLELIT-WV.PFNIVA..YDPKy..rRVDNdKI......IWYDRLF.DRND.IETIESKSYIYIDIRTD..VRNLDTTKKQRIFKEEDDMIVDMAIKL-ASKQCTVMFKRKIFPGNN.MSFGDPLFHPKLTQLGREYYNCITTIVSPSVyKESELYSLLLSARS...NNVSNYVYGGSKFDQfsIV..NCNST..VVALYSLSNTVNSLktiEHAIKYNHIIT.FPHRTDRgdWRNIEELDN.........SSPFQNRkrqlefEDWSIDPKNYVMKFRCEMVSESVFLQ---LGHSRALIPDLYNHMISLRMEMPLFYSDRFFSHIGIRQPSIFKRDSYMTSRLSAYISRQLTHS.iNL..SVLKRNHFEGY..SGHLIA--.------------------.-----------------------------------------------------ietsfsslvftmspyrwlirakklltknkmrdkfkigdgqphtreefentyd
VP3_ROTHC/1-692                      .................MRVLGLFERGNNLNFADTYVYTWNQQYSYHENAFLISNQVATTIILYLDGININEVNKAFELLNSNGIPALIIKP-DHIG.IFTSSNFTYDWQYKIVYFHEYTYYKNNEFIVSDEFWLY-TNINE-LLP-YKILYYERGMRELYAGRE--------YTLYNTATDDDILYKYIYEKDSIMNGTDYKKLYDTNSVKNFVHFMRLLRMRFAVPFDQLSNRITRSRVF------SKSRIH.IGLRNESIPQALDNIHS.QWINY..S-----ANG-------IVISELKGLG.SYSEKKISEFGIGQFKNYMNFLTLMFYIKNM.-KKKPSC.TIIGAAPGYWISSMKKY-.-FTIVT..YDNK....EVD-.ST......EHHNRYF.TDDD.IVNVKTNGV-YIDVRSE..FKTNDWRQRRKLIEEETIKWLEISYKLLENKRVEAILLKMTAMDGE.IP-DGYCVHSPTTYRKSEYYLLIDKHIIKRQ.KIKVTKSLMYNAIN...TIYSDNVFISGKYSL..RG..KTEG-..VLALYCLSNTINQK...EKVIQYANSFS.GTCMTVR..LNNTYEVDK.........IIDFKTN......SDHTFLPSDFTCSLNTILTSYRGYAGIFGYAITKDLKSNGNNHIYIIPNARDENNFDTFGSHLGLSRYSHSKRFSESATTMSGYIFRDMVSG..KE..NMQDTDKDNYA..SGHVFNAI.AHYRFDYTYDIVGWLRLH.KTGQFKVKSDIYKEHTDSEIRNAIESAYVYYLLDGDKVGEKYSKKMMEIWEVQ....................................................
D0TZ85_9VIRU/1-394                   .................MKVLALRHSVAQV-YADTQTYVHDDSKDEYENAFLISN-LTTHNILYL-----NYSVKTLKILNKSGIAAVEVQSPDELF.ALIRCNFTYDYENNIVYLHDYSYYTNNE-IRTDQHWVTKTDIIDYLLPGWKLTYVG------YNGKDTRGHYNFSFTCQNAATDDDIIIEYIYSN-----ELDF---------QTFLLRKIKERMTTSLPIARLSNRVFRDKLFPFIVNIHKKVIN.VGPRNESM--------F.TFLNF..PNIKQFSNGAYLVKHTIKLKQERWLG.----KRVSQFDIGQYKNMLNVVTTIYYYYNL.HSSKPII.YMLGSAPSYWIYDIKQYS.DFTFET..WDPL....DTPY.ST......THHKELF.FDKD.VNKLKDNSILYIDIRTD..REDMDWKEWRKVVEQQTISNLNIAYKYLSTGKAKVCCVKLTAMDLE.LPI----------------------------.--------------...---------------..--..-----..--------------...-----------.-------..---------.........-------......--------------------------------------------------------------------------------------------..--..-----------..--------.------------------.-----------------------------------------------------t...................................................
L0CSA3_9VIRU/1-683                   .................MKVIALRRDLVSS-YADTQVYEHDVSKDYYENAYLISN-ITAHNVLYV-----DYSIQVIEILNKSGIASLVAVNKDELE.ILIKSNYTYDYYKNIVYLHDYSYYNLNE-LRTDQYWLTTTNIEEYILPGWKLTYVG------QLGIKTRGHYTYSFICQNTATDDDIIYDYIYSS-----EVDF---------LPFLLQALNKRLTTALNFHRLSNRIFREYLYSG---VPKDTIN.IGPRNESM--------F.TLLRY..PYIMNYAANEFKVSDLIKLTQEKWVG.----TENSQFDIGQFKNMCNVLSTIYYYYNK.YHAYPRI.YMLGSAPSYWLYDLLQVH.DFDIET..WDPL....DTPF.SK......WHHKAMF.TISD.TEKLSDNSILYIDIRSD..RNGVDWKEWRQRVEYETKINLEIMYKYLQCGKNRICCCKITAMDIE.LPVTSILLHFPTTKIQSECYVICTQEMLRDK.KRFVPKGAFYSFIN...NTKTDNVFISPVYKV..KP..TNK-F..VVALYSLSNENNDR...DKVINFTQKQK.RGVITLR..MNNTFNYEY.........RLQFKST......YDYLYLPSEVSRE-GTIVTSYDGYIAMHNLSLSLESKATGNNHLFISFSDTNYDQIDSYCNHMGISRRSHSVRFSEAATTLSGYMFRDITNG..KF..NLINTNVENAV..SGHVYNAL.VYFRYNYRFDLLRWINLH.AKDEVMIQGGRYYEHAPPELLYACHSALTFAKSQNDLTLIEYVNS-VNSYI--lt..................................................
M4H253_9VIRU/1-690                   ..............mrm---LICNKQQLRRQAANSSIYTYNTELSQYENAFLCSN--VTTDIVFVDTNHDQSMSNFVNILRTNGIARVDVRKSDELFdILVSSSFIFDYKSSTIYLMDYSYYKEFD-LATDQFWAY----EELKNAGYKIEYTG------YMGRE-RMKFIGNYFLTNIATDDDIISAYIYDA----CIIDF---------KQFLFQKKLERLSHALDFNRLESRVLRHVIYSRSI---YNH-I.VGPRNESA------IAL.LWSNM..K-FRHYANN---LPVAINIMR-QGTS.KFAERINSQFDIGQYKNMMNFLTVWFRYITV.YGKSPDCaYIIGSSPARWLKDIPQHI.LEKIFT..YDPK....ETEF.SL......HHFKQLF.EISD.VKSLSNNSVVYIDIRTDgdRSYSNWEKRRNQVETESMKNMELAQMILKLKRNCIVMYKLTAMDFN.IPVNAYFIHFPTTNTRSEFYLLQDELSAT--.-EYVTKGNCYYAIN...NFTSDNVFISPKFHL..TK..RNKGR.eVCALYALSNVINIK...TDVLQYINQTN.KGVYTLR..LANDFDLSC.........TIKFKDG......ADFLTLPTELRSDDNTLITSHRGALGYYNLCTTHDDKPTGNNHIYIIKNVIKPID-DTYAGHYSISRRSHTVRFSETATKLAGYMFRDLVANgpDY..KLSNTDINNSA..SGHVCNAI.IYYRHNYTFDLMNWLRKH.AIGTYKIVGGRYEKHAVKEILNAIESAIMFTRLNNDLTGQNYAQQCKDV----fnaf................................................
A0A0K0LBN7_9VIRU/98-654              ...........ppselc--------------------------------------------------------------------------------.----------------------------------------------------------------------------------NDDDILTNYLYRS---NKSVKF---------EEFIQQKILERLSFALRHEKYESRLLRTKVF-NLYKNEKP-II.IGPRNESM---FELLSL.NFTYY..S-----ANE-FTVKDLSSLQSSRF--.--REITLNEFDVGQYKNMLNFLSLYYYHVNH.YGLPNRI.VIIGSYPSKWLILLRNS-.GLNCETilYDVKlddsQKDIrEF......IFRNKFY.TFDDsYTDIIDNSIVYLDARIE..YSRDSEIDRRKKIESDTKIYFEWCDHLVRYFNKVTVMCKYTAMSGN.LYKNIKLVNHIRTSIRSEVYLLFNIDDVSSE.KIYIDKGKIYSFIQ...NHITDNVFIGKTFKV..TK..MNKSTrpVVALYSLSNTLNDR...KLCLSYINTTR.RGILTYR..ARNNFTNED.........VITYDKF......KDYSCLRTELKSNDNSIVTSLSGALGVFGCQTTFNDKADGNVHFHVIKGIER-TNIDKYASHLQISRRSQFLRFTETATSLSGYLFRDLASE..GFsnDLSETDSNNAA..SGHVYNAL.IYFRYNWRFDLIYWMEKHiNSNQIQSVGTNYYKHSIREIVNAINAAKKYAELQNDETLVNYINTLIQLY---ptn.................................................
A0A222NY40_9VIRU/1-211               .................MKVLALRHSVAQV-YADTQTYLHDDSKDEYENAFLISN-LTTHNILYL-----NYSLKTLKILNKSGIAAVEVQSPDELF.TLIRCNFTYDYENNIIYLHDYSYYTNNE-IRTDQHWITKIDITDYLLPGWKLTYVG------YNGKNTRGHYNFSFLCQNAATDDDIIIEYIYSN-----ELDF---------QNFLLRKIKERMTTSLPIARLSNRVFRDKLFPSIVNTYKKVIN.IGP--------------.-----..--------------------------.-------------------------------.-------.------------------.------..----....----.--......-------.----.-----------------..----------------------------------------------.-------------------------------.--------------...---------------..--..-----..--------------...-----------.-------..---------.........-------......--------------------------------------------------------------------------------------------..--..-----------..--------.------------------.-----------------------------------------------------....................................................
A0A0D3Q2F6_9VIRU/1-345               .................MKVLALRHSVAQV-YADTQTYVHDDSKDEYENAFLISN-LTTHNILYL-----NYSVKTLKILNKSGIAAIEVQSPDELF.ALIRCNFTYDYENNIVYLHDYSYYTNNE-IRTDQHWVTKTDIIDYLLPGWKLTYVG------YNGKDTRGHYNFSFTCQNAATDDDIIIEYIYSS-----ELDF---------QTFLLRKIKERMTTSLPIARLSNRVFRDKLFPFIMNIHKRVIN.VGPRNESM--------F.TFLNF..PTIKQFSNGAYLVKHTIKLKQERWLG.----KRVSQFDIGQYKNMLNVVTTIYYYYNL.HSSKPII.YMLGSAPSYWIYDIKQYS.DFTFET..WDPL....DTPY.ST......IHHKELF.FEKD.VNRLKDNSILYIDIRTD..R---------------------------------------------.-------------------------------.--------------...---------------..--..-----..--------------...-----------.-------..---------.........-------......--------------------------------------------------------------------------------------------..--..-----------..--------.------------------.-----------------------------------------------------....................................................
A0A125RLH0_9VIRU/1-683               .................MKVIALRRDLVSS-YADTQVYEHDVSKDYYENAYLISN-IIAHNVLYV-----DYSIQVIEILNKSGIASLIAVNKDELE.ILIKSNYTYDYYKNIVYLHDYSYYKLNE-LRTDQYWLTTTNIEEYILPGWKLTYVG------QLGIKTRGHYTYSFTCQNTATDDDIIYDYIYSS-----EVDF---------LPFLLQALNKRLTTALNFHRLSNRIFREYLY---SEVPKDTIN.VGPRNESM--------Y.TLLRY..PYIMNYAANEFKVSDLIRLTQEKWVG.----TENSQFDIGQFKNMCNVLSTIYYYYNK.YHAYPRI.YMLGSAPSYWLYDLLQVQ.NFDIET..WDPL....DTPF.SK......RHHKTMF.TTSD.IEKLNDNSILYIDIRSD..RNGVDWREWRQRVEDETKVNLEIMYKYLQRGKNRICCCKITAMDIE.LPITSILLHFPTTKIQSECYVICTQEMLQDK.KRFIPKGAFYAFIN...NTKTDNVFISPVYKV..KP..TNK-F..VVALYSLSNENNDR...DKVIDFTQKQK.RGVITLR..MNNTFNYEY.........RLQFKST......YDYLYLPSEVSRE-GTIVTSYDGYIAMHNLSLSLESKATGNNHLFISFSDANYDQIDSYCNHMGISRRSHSVRFSEAATTLSGYMFRDITNG..KF..NLINTNVENAV..SGHVYNAL.VYFRYNYRFDLLRWIDLH.AKDKAMIQGGRYYEHAPPELLYACQSALVFAKLQNDLTLIEYVNS-VNRYI--lt..................................................
E7D6N4_9VIRU/1-568                   .................MKVLALRHSVAQV-YADTQTYLHDDSKDEYENAFLISN-LTTHNILYL-----NYSLKTLKILNKSGIAAVEVQSPDELF.ALIRCNFTYDYENNIIYLHDYSYYTNNE-IRTDQHWITKTDITDYLLPGWKLTYVG------YNGKNTRGHYNFSFLCQNAATDDDIIIEYIYSN-----ELDF---------QNFLLRKIKERMTTSLPIARLSNRVFRDKLFPSIVNMYKQVIN.VGPRNESM--------F.TFLNF..PTIKQFSNGAYIVKHTIKLKQEKWLG.----KRVSQFDIGQYKNMLNVVTTIYYYYNL.YHSKPIV.YMLGSAPSYWIYDIKQYS.DFTFET..WDPL....DTPY.ST......LHHKELF.FDKD.VNKLKDNSVLYIDIRTD..RKNMDWKEWRKVVEQQTVNNLNIAYKYLAIGKAKVCCVKLTAMDLE.LPITAKLLHHPTTEIRSEFYAILDVWDIITI.KRFIPKGVFYAFIN...NIITENVFIQPPFKL..KV..SPTSY..IVALYALSNDFNSR...QDVINLINKQK.QSLITVR..INNTFKDEP.........KVNFKNI......YDWTFLPTDFELK-DSIITSYDGCLGMFGLSISLSSKPTGNNHLFIINGTDKYYKLDQYANHMG----------------------------..--..-----------..--------.------------------.-----------------------------------------------------....................................................
I6WJT2_9VIRU/1-291                   .................MKVLALRHSVAQV-YADNPGYAHDDTKDSYENAFLISS-LTTHNILYL-----NYSIKTLEILNKSGIAAIALQSLKRLF.TLIRCNFTYDYELDIIYLHDYSYYTNNE-IRTDQHWITKTNIEEYLLPGWKLTYVG------YNGSETRGHYNFSFKCQNAATDDDLIIEYIYSE-----ALDF---------QNFMLKKIKERMTTSLPIARLSNRVFRDKLFPSLLKEHKNVVN.VGPRNESM--------F.TILNY..PTIKQFSNGAYLVKDTIKLKQERWLD.----KRISQFDIGQYKNMLNVLTAIYYYYNL.YRSKPII.YMIGSAPSY---------.------..----....----.--......-------.----.-----------------..----------------------------------------------.-------------------------------.--------------...---------------..--..-----..--------------...-----------.-------..---------.........-------......--------------------------------------------------------------------------------------------..--..-----------..--------.------------------.-----------------------------------------------------....................................................
E2EBU2_9VIRU/1-681                   .....mrlvvcsdeqsk------------TPLVNATLYRYRSNVHPAENAFLACNQIA-EIILVI---NCSNFDKFSENVRSNGICCVDTRGNDDLF.KSVVSGNCLFNENEVIT-IDYGYYRYKT-LRTMFTYIF-----S--FP--KTEFKW----ESVPPSE-------------LCNDDDILTNYLYRSD---KSVKF---------EEFIQQKILERLSFALRHEKYESRLLRTKVY-NLYKNEKP-IV.IGPRNESM---FELLSL.NFTYY..S-----ANE-FTVKDLSSLQSSRF--.--REITLNEFDVGQYKNMLNFLSLYYYHVNH.YGLPNRI.VIIGSYPSKWLILLRNSGlNCEIIL..YDVK....LDD-.SQkdirefVFRNKFYtFDDS.YTDIIDNSIVYLDARIE..YSRDSEIDRRKKIELDTKIYFEWCDRLVRHFNKVTIMCKYTAMNGN.LYKNIKLVNHIRTSIRSEVYLLFNIDDVSSE.KVYIDKGKIYSFIQ...NHITDNVFIGKTFKV..TK..INKSTrpVVALYSLSNTLNDR...KLCLSYINTTR.RGILTYR..ARNNFTNED.........LISYDKF......KDYSCLRTELKSSDNSIVTSLSGALGVFGCQTTFNDKADGNVHFHVIKGIER-TNIDKYALHLQISRRSQFLRFTETATSLSGYLFRDLASE..GFsnDLSETDSNNAA..SGHVYNAL.IYFRYNWRFDLIYWMEKHiNSNQIQSVGTNYYKHSIREIVNAINAAKKYAELQNDETLINYINTLIQLY---ptn.................................................
A0A1L6BXK9_9VIRU/188-702             dydvqsynyritrreig--------------------------------------------------------------------------------.--------------------------------------------------------------------------------------------------------------------------------------------NKVRDLVFNMCKGKIHlIGPELESV----RNI-V.QYLNMkgNTIKILHVK-HHEKNLIMT--QRGAAfRRRKLKFSNLLAPQRKNQNNFVKGLIHHLNKsSAIVDRV.YYIGAYPSYWLENMRWI-.NFQIVC..YDPKfrlvDNP-.NV......LWRDKLF.LDED.IENVENGSYVYIDIRSD..IRTQSDVVKNKIFKDEDNMILDLTRKLVK-KRCTVM-AKRKIVEQDiVSIGEECYPPGENQIGREFYNLADASSVEKL.--LTQKEVFAKIVNarsNNKQNYVYGGTKFDS..STiiEDDET..VIGLYSLSNSFNSL...ATIEHVIKSNHiITFPTDR..EHGDWRDISkaqskpfvgKIKQLNF......EDWAVNPKAYCKKYNVEMLAEQVF---LQYGNTRAFIPDLYCHMISTNMAEKLKYSDRFFAHIGIRQPSIYARDKYMTSRISAYISRKLTHG..-I..DLRDLERDNFAgySGHLIAIEtSFNSLVYTMSPFRWIQR-.-----------------------------------------------------aqrretrkdkfqigkgephtkeeykntydyldd...................
K9L4Q7_9VIRU/1-687                   .................MKVLALRHDVVQS-YADTQIYKHNDRKDAYENAFLISN-LTSHNVLYY-----DYSPKVLEILNKSGIAAVQVDNDAELT.LLLSANFTYNFEDNIVYLHDYSYYTYNE-LRTDQFWLTKSNITDYIFPGWVMTYVG------YNGLLTRGHYNYSFTCQNAATDDDIIIDYIYSQ-----ELDF---------QNFLLKKMKERMTTALPVARLSNRVLRDKLFPELLKKHQRVCN.IGPRNESM--------F.TFLNY..PTIKQYSNGSYRVKDTITLRQERWLG.----KRISQFDVGQYKNMLNVITTVYHFYDL.YAFKPII.YMVGSAPSYWIKDVQAYS.QFEYET..WDPL....PTPF.ST......KHHASMF.TIDD.VPKLKNGSVLYIDIRTD..RGNIDWQKWRTIVQEQTLSNLRLAYEYLSSGKQKVCCVKMTAMDLE.LPVMAKLLHHPTTEVRSEYYLLLDQNDMSSI.RRYVTKGMMYAYIN...NVTTENVFIQKPFKV..KP..VNNSY..IVALYALSNDFNDR...QSVVELVNKQK.KGIITVR..LNNTFDDST.........KVGFKNI......YDWTFLPTDFATN-DTIITSYTGCLGMFGLSISLLQKATGNNHLFCITGGDEYYKLDQFANHMSISRRSHQIRFSESATSFSGYIFRDLSNN..NF..NLIDTNVDNSV..SGHVYNAL.IYYRYNYSFDLKRWIYLH.AVNDVRVEGGKYYEHAPIELIYACRSAKDFAIVQNDLTVLRYASE-IEKYINT....................................................
VP3_ROTSH/1-687                      .................MKVLALRHSVAQV-YADTQVYVHDDTKDSYENAFLISN-LTTHNILYL-----NYSIKTLEILNKSGIAAIALQSLEELF.TLIRCNFTYDYELDIIYLHDYSYYTNNE-IRTDQHWITKTNIEEYLLPGWKLTYVG------YNGSETRGHYNFSFKCQNAATDDDLIIEYIYSE-----ALDF---------QNFMLKKIKERMTTSLPIARLSNRVFRDKLFPSLLKEHKNVVN.VGPRNESM--------F.TFLNY..PTIKQFSNGAYLVKDTIKLKQERWLG.----KRISQFDIGQYKNMLNVLTAIYYYYNL.YKSKPII.YMIGSAPSYWIYDVRHYS.DFFFET..WDPL....DTPY.SS......IHHKELF.FIND.VKKLKDNSILYIDIRTD..RGNADWKKWRKTVEEQTINNLDIAYEYLRTGKAKVCCVKMTAMDLE.LPISAKLLHHPTTEIRSEFYLLLDTWDLTNI.RRFIPKGVLYSFIN...NIITENVFIQQPFKV..KV..LNDSY..IVALYALSNDFNNR...SEVIKLINNQK.QSLITVR..INNTFKDEP.........KVGFKNI......YDWTFLPTDFDTK-EAIITSYDGCLGLFGLSISLASKPTGNNHLFILSGTDKYYKLDQFANHTSISRRSHQIRFSESATSYSGYIFRDLSNN..NF..NLIGTNIENSV..SGHVYNAL.IYYRYNYSFDLKRWIYLH.SIDKVDIEGGKYYELAPIELIYACRSAKEFATLQDDLTVLRYSNE-IENYINT....................................................
A0A1B4XK04_9VIRU/1-687               .................MKVLALRHSVAQV-YADTQVYTHDDSKDDYENAFLISN-LTTHNILYL-----NYSVKTLQILNKSGIAAIEIQKMDELF.TLIRCNFTYDYIDDIVYLHDYSYYTNNE-IRTDQHWVTKTNIEDYLLPGWKLTYVG------YNGSDTRGHYNFSFKCQNAATDDDAIIEYIYSN-----ELDF---------QNFILKKIKERMTTSLPIARLSNRVFRDKLFKTLSANHDRVVN.VGPRNESM--------F.TFLDH..PSIKQFSNGPYLVKDTIKLKQERWLG.----KRLSQFDIGQYKNMLNVLTTLYQYYDV.YHEKPVV.YMIGSAPSYWIYDIRQYS.DLKFET..WDPL....DTPY.SD......LHHKELF.YIND.VQKLKDNSILYIDIRTD..RGNMDWKEWRKVVEGQTIGNLHIAYKYLSTGKAKICCVKMTAMDLE.LPISAKLLHHPTTEIRSEFYLMMDIWDSKNI.KRFIPKGVLYSYIN...NTITENVFIQQPFKL..KT..LKNEY..VTALYALSNDFNNR...EDVIKLINNQK.KALITVR..INNTFKDEP.........KVGFKNI......YDWTFLPTDFETS-GSIITSYDGCLGIFGLSISLASKPTGNNHLFILSGTDKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNN..NF..NLIGTNIENSV..SGHVYNAL.IYYRYNYSFDLKRWIYLH.STGKASIEGGKYYEHAPIELIYACRSAREFAKLQDDLTVLRYSNE-IENYIN-r...................................................
VP3_ROTS1/1-687                      .................MKVLALRHSVAQV-YADTQVYVHDDIKDSYENAFLISN-LTTHNILYL-----NYSIKTLEILNKSGIAAIALQSLEELF.TLIRCNFTYDYELDIIYLHDYSYYTNNE-IRTDQHWITKTNIEEYLLPGWKLTYVG------YNGSETRGHYNFSFKCQNAATDDDLIIEYIYSE-----ALDF---------QNFMLKKIKERMTTSLPIARLSNRVFRDKLFPSLLKEHKNVVN.VGPRNESM--------F.TFLNY..PTIKQFSNGAYLVKDTIKLKQERWLG.----KRISQFDIGQYKNMLNVLTAIYYYYNL.YKSKPII.YMIGSAPSYWIYDVRHYS.DFFFET..WDPL....DTPY.SS......IHHKELF.FIND.VKKLKDNSILYIDIRTD..RGNADWKKWRKTVEEQTINNLDIAYEYLRTGKAKVCCVKMTAMHLE.LPISAKLLHHPTTEIRSEFYLLLDTWDLTNI.RRFIPKGVLYSFIN...NIITENVFIQQPFKV..KV..LNDSY..IVALYALSNDFNNR...SEVIKLINNQK.QSLITVR..INNTFKDEP.........KVGFKNI......YDWTFLPTDFDTK-EAIITSYDGCLGLFGLSISLASKPTGNNHLFILSGTDKYYKLDQFANHTSISRRSHQIRFSESATSYSGYIFRDLSNN..NF..NLIGTNIENSV..SGHIYNAL.IYYRYNYSFDLKRWIYLH.SIDKVDIEGGKYYEHAPIELIYACRSAKEFATLQDDLTVLRYSNE-IENYINT....................................................
D7NN51_9VIRU/1-687                   .................MKVLALRHSVAQV-YADTQIYIHDETKDDYENAFLISN-LTTHNILYL-----NYSVKTLQILNKSGIAAVEIQKMDELF.TLIRCNFTYDYIDDVVYLHDYSYYTNNE-IRTDQHWVTKTNIEDYLLPGWKLTYVG------YNGNDTRGHYNFSFKCQNAATDDDAIIEYIYSN-----ELDF---------QNFILRKIKERMTTSLPIARLSNRVFRDKLFKTLVSDHSKIVN.VGPRNESM--------F.TFLDH..PSIKQFSNGPYLVKDTIKLKQERWLG.----KRLSQFDIGQYKNMLNVLTTLYQYYDM.YHEKPII.YMLGSAPSYWIHDVKQYS.NLKFET..WDPL....DTPY.SD......LHHKELF.YISD.VTKLKDNSILYIDIRTD..RENADWKTWRKIVEEQTVNNLNIAYKYLSTGKAKVCCVKMTAMDLE.LPISAKLLHHPTTEIRSEFYLIMDIWDSKNI.KRFIPKGVLYSYIN...NIITENVFIQQPFKL..KT..LRNEY..VVALYALSNDFNNR...EDVIKLINNQK.NALITVR..INNTFKDEP.........KVGFKDI......YDWTFLPTDFETN-ESIITSYDGCLGVFGLSISLASKPTGNNHLFILSGTNKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNN..NF..NLIGTNVENSV..SGHVYNAL.IYYRYNYSFDLKRWIYLH.STNKASIEGGRYYEHAPIELIYACRSAREFAKLQDDLTVLRYSNE-IENYIN-k...................................................
#=GC seq_cons                        .................MKVLALR+slsps.YADTphYhHcspKD.YENAFLISN.lsTHNILYl.....sYS.KslcILNKSGIAAltlps.DELh.hLlpsNFTYDYppsIlYLHDYSYYppNE.lRTDQaWlTpTsIp-YlLPGWKLTYVG......YsGpcTRGHYsaSFhCQNsATDDDIIh-YIYSp.....tlDF.........psFlLpKlpERMTTuLPhsRLSNRlhR-KLF.plhp.aKphlN.lGPRNESM........h.saLsa..s.IcpauNu.ahVKchIpLppc+alG.....++lSQFDIGQYKNMhNhLTslYYaYNh.YptpPhl.YhlGSAPSYWlhsl+pa..sFph.T..aDPh....-ssh.Sp......hHHcchF.h.sD.lpclcsNSllYIDIRoD..hps.DWpchR+hlEppTh..Lclsh+hLppt+splhhsKhTAM-h-.lPhsshhlHaspTplpSEhYllhs...hpp..+hhlsKuhhYshIN...Nhho-NVFIt..acl..ps..hspth..llALYuLSNshNs+...ppllphhpppp.tshhThR..hpNsap.p..........hltFcsh......hDashLPo-hppp.psIlTShpGhluhashuhohs.KssGNNHhall.sspc..phDpassHhuISRhSp.hRFoEsATphSGYhFRDlsss..th..sl.tTshpN.s..SGHlhNAl.haaRasapaDlhhWh.hH.t.tph...us.Y.chs..El..AhpuAh.ah..psD.sh.pY.pp.hp.........................................................
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