#=GF ID   SNAD2
#=GF AC   PF18745.5
#=GF DE   Secreted Novel AID/APOBEC-like Deaminase 2
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Iyer LM
#=GF GA   25.00 25.00;
#=GF TC   27.20 26.60;
#=GF NC   24.40 24.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0109
#=GF RN   [1]
#=GF RM   29555751
#=GF RT   Diversification of AID/APOBEC-like deaminases in metazoa:
#=GF RT   multiplicity of clades  and widespread roles in immunity.
#=GF RA   Krishnan A, Iyer LM, Holland SJ, Boehm T, Aravind L;
#=GF RL   Proc Natl Acad Sci U S A. 2018;115:E3201.
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A family of secreted AID/APOBEC like deaminases found in
#=GF CC   ray-finned fishes [1].
#=GF SQ   3
#=GS A0A8J1M3N1_XENLA/29-227  AC A0A8J1M3N1.1
#=GS A0A1L8HVL8_XENLA/24-223  AC A0A1L8HVL8.1
#=GS A0A8J0R4H3_XENTR/29-227  AC A0A8J0R4H3.1
A0A8J1M3N1_XENLA/29-227             ................................................................................LLRATNFIRQEKT..GG.LNNQYAY...VAL..F....TVAQCR...Q..L..A..DADLR..D.A..L.RQ....EDA.A...N....L..V.M..T.V...A..D...Q..Q...I..Y...R..GT..K....MVAAS...Y..L......Q.I....D....NQ....H....A...VHAEARLLN...G.E...G.N....A...P..S...P.VQDL.I.N..R.N..ED.....R.GCVLFYTLN.SPCTGLCVRIGG...QYNILNK.L.N...V.F...D..N..I..N..N...R...AL...VYND.V.....Y.F..ADL.T..R......K..E...D.....I.....VW..AAWA..AVNA...RI...GFYRC..F....N....N....R.....CVRCFK.NGTQN--SN-cy..................................................
A0A1L8HVL8_XENLA/24-223             ................................................................................LFRATNYIHKTIT..RG.INVQYSY...VAV..F....TADQCI...N..L..N..IEDLM..N.A..L.RE....ENA.S...V....L..V.K..M.V...K..S...K..K...I..Y...E..GP..R....MVAAS...Y..L......R.L....D....NG....S....A...VHAEARLLN...G.K...G.G....A...P..S...P.VQNL.L.N..I.N..QD.....K.GCVLFYTLN.SPCTRYCAKVGG...RYNILSR.L.D...I.F...N..G..I..Q..N...R...AL...VYNE.V.....Y.H..DEF.D..K......N..E...T.....D.....VW..AAWA..AINR...RI...DFYRC..T....N....N....Q.....CYRCFE.YNTGSRNTDC....................................................
A0A8J0R4H3_XENTR/29-227             ................................................................................LLRATNYIRQHLT..GR.INNQYAY...IAV..F....TTAQCR...E..L..T..DANLR..D.A..L.RQ....ENA.D...D....L..M.T..T.I...E..Q...H..R...I..Y...I..GT..Q....IVAAS...F..L......R.L....N....NG....G....A...MHAEARLLN...G.E...G.E....A...P..S...P.VADL.L.N..R.N..QD.....K.GCVLFYTLN.SPCTGVCARIGG...EYNILDR.LtD...V.F...N..R..I..N..N...K...AL...VYND.V.....Y.I..GDL.N..R......K..P...D.....T.....VW..DAWK..EINA...RI...PFYRC..F....S....R....N.....CYRCFI.NNN-------pnnpc...............................................
#=GC seq_cons                       ................................................................................LLRATNYIRQclT..GG.INNQYAY...VAV..F....TsAQCR...p..L..s..DADLR..D.A..L.RQ....ENA.u...s....L..V.p..T.V...c..s...+..+...I..Y...c..GT..+....MVAAS...Y..L......R.L....D....NG....u....A...VHAEARLLN...G.E...G.s....A...P..S...P.VQDL.L.N..R.N..QD.....K.GCVLFYTLN.SPCTGlCARIGG...cYNILsR.L.D...V.F...N..s..I..N..N...R...AL...VYND.V.....Y.a..uDL.s..R......K..E...D.....s.....VW..AAWA..AINA...RI...sFYRC..F....N....N....p.....CYRCFc.NNTts..os.s...................................................
//