#=GF ID   SduA_N
#=GF AC   PF21407.1
#=GF DE   Shedu protein SduA, N-terminal
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Manual
#=GF GA   27.00 27.00;
#=GF TC   33.50 45.40;
#=GF NC   26.30 22.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   29371424
#=GF RT   Systematic discovery of antiphage defense systems in the
#=GF RT   microbial pangenome.
#=GF RA   Doron S, Melamed S, Ofir G, Leavitt A, Lopatina A, Keren M,
#=GF RA   Amitai G, Sorek R;
#=GF RL   Science. 2018; [Epub ahead of print]
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found mostly in bacteria. It is found at the
#=GF CC   N-terminal of Shedu protein SduA, the only component of
#=GF CC   antiviral defense system Shedu. Expression of Shedu in
#=GF CC   B.subtilis (strain BEST7003) confers resistance to phages
#=GF CC   phi105, phi29, rho14 and to a lesser extent to SPP1 [1].
#=GF SQ   10
#=GS R7KDX1_9FIRM/10-111      AC R7KDX1.1
#=GS A0A563AE85_9BACT/10-105  AC A0A563AE85.1
#=GS A0A328UC81_9FIRM/22-130  AC A0A328UC81.1
#=GS I8UEQ0_9BACI/7-108       AC I8UEQ0.1
#=GS Q5ZWL2_LEGPH/18-118      AC Q5ZWL2.1
#=GS A0A6B2DE35_9PSEU/11-112  AC A0A6B2DE35.1
#=GS A0A417NCX7_9FIRM/8-103   AC A0A417NCX7.1
#=GS A0A563D6S7_9BACT/10-105  AC A0A563D6S7.1
#=GS A0A174BZC3_9FIRM/10-118  AC A0A174BZC3.1
#=GS A0A4Z0LTR8_9GAMM/8-109   AC A0A4Z0LTR8.1
R7KDX1_9FIRM/10-111                 .STSNITADMTPIViLDETTRTQVRFELQQIDNGKDPEKKLKGKFIYTVANKNtGSF......DDIIRL....NKKS..IKAGESFELALSCKETYQLWQHLTERYKLVE-------gkltp....
A0A563AE85_9BACT/10-105             s-VVAGVAEVNDVI.IDDSPRTRIVFRPMIH------QNGIRGDIIRFRKRSN.GEL......IEPVPL....NFNQ..LNENDGVKIEMKTETLAKLYEEISKLAQLLQDRGVRYG.........
A0A328UC81_9FIRM/22-130             .STSSVTATASPIV.LNQTDMLRFKFLPTLVKNEKEPHKSVSGKLLYEKKRKS.GDAfpsdgnASAERV....SRGS..VKVGDWMEFQLDTSETYELYIGLKRLYDLFDDVG----eipyg....
I8UEQ0_9BACI/7-108                  .STSKDSAMGTDII.LRENSLTRLIFRPQIVNNQKDINAPVNGCFIFQKKKKA.DMW......EDFKDF....NLSS..LKAYEGIKLELKSEEMLKLMTEADAYYKIHREYGIVQG.........
Q5ZWL2_LEGPH/18-118                 .STSSSSAEIEDIE.FSRTSTTRRIIRPMIVENNERPDASIKIEIIHQK-AEK.GLF......EDIPTE....KLSK..YKAKDIGKLVLSSEETLSLFNHLCNLYLIHKENGIPSG.........
A0A6B2DE35_9PSEU/11-112             .STSRTTADVTSVV.LRDGRRKRLVFAPVLVENEGEPGATVRGELAYYSKNAA.DEW......VRDKPF....DLRT..LAAGESVRLDLSSGELLKLFNCVAALYEHMADAGFE--yg.......
A0A417NCX7_9FIRM/8-103              .TVGTGFAEIGESV.LTETTQTAIVFKPQMH------EGGIRGSIIRYKKGRN.GDR......ETPVPV....DFRR..LNAGDGIEIELNTEAVTNLTQRIQEIQALLDEEGVRPG.........
A0A563D6S7_9BACT/10-105             s-VVAGVAEVNDVI.IDDSPRTRIVFRPMIH------QNGIRGDIIRFRKRSN.GEL......IEPVPL....NFNQ..LNENDGVKIEMKTETLAKLYEEISKLAQLLQDRGVRYG.........
A0A174BZC3_9FIRM/10-118             .STSATTADATPVV.LSETERMRFRFVPTIVDNQSSPECTVRGKILFERKPQN.DKF......FPTDTVapceRITRgtAKKGDWIELELHSKETYNLFMGLKRLYDLS--------gcmdgipfg
A0A4Z0LTR8_9GAMM/8-109              .STSRVTAQATDIV.LRQTDSIRLIFRPTIIDNVKNKEAALKGIFLYQKKSKK.AAW......EDFETI....PLSS..VKGGEGYKLEIKTAELLQLFQELTQLYELHQKEGVPRG.........
#=GC seq_cons                       .STSssoA-so-lV.Lc-TspTRllF+PpIlcNtpp.csul+GclIap+Kscs.Gca......t-shsl....shsp..lKuGDul+LELcocEhhpLapclscLYcLhp-tGl..G.........
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