#=GF ID Slr4
#=GF AC PF19526.3
#=GF DE S-layer protein Slr4
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Lobb Braillen
#=GF GA 25.00 25.00;
#=GF TC 25.40 25.40;
#=GF NC 22.80 22.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 32804439
#=GF RT Slr4, a newly identified S-layer protein from marine
#=GF RT Gammaproteobacteria, is a major biofilm matrix component.
#=GF RA Ali S, Jenkins B, Cheng J, Lobb B, Wei X, Egan S, Charles TC,
#=GF RA McConkey B, Austin J, Doxey AC;
#=GF RL Mol Microbiol. 2020; [Epub ahead of print]
#=GF DR INTERPRO; IPR045689;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family represents a novel S-layer protein widely
#=GF CC distributed in Gammaproteobacteria including species of
#=GF CC Pseudoalteromonas and Vibrio, and are found exclusively in
#=GF CC marine metagenomes. These proteins assemble into paracrystalline
#=GF CC sheets with a unique square lattice symmetry [1].
#=GF SQ 33
#=GS A0A1H7H9B6_9GAMM/58-429 AC A0A1H7H9B6.1
#=GS A0A1W6MHC5_9FLAO/100-261 AC A0A1W6MHC5.1
#=GS H5TF71_9ALTE/58-486 AC H5TF71.1
#=GS A0A1H4A0K5_ALKAM/3-306 AC A0A1H4A0K5.1
#=GS A0A4V5NW09_9GAMM/59-442 AC A0A4V5NW09.1
#=GS A0A4U1BLU7_9GAMM/59-441 AC A0A4U1BLU7.1
#=GS A0A0A7EEU5_9GAMM/85-499 AC A0A0A7EEU5.1
#=GS A0A4P6VRZ7_9GAMM/87-582 AC A0A4P6VRZ7.1
#=GS A0A094ITL9_9GAMM/99-558 AC A0A094ITL9.1
#=GS A0A2S2E0N4_9ALTE/78-457 AC A0A2S2E0N4.1
#=GS A0A2T4CU89_9GAMM/44-433 AC A0A2T4CU89.1
#=GS A0A6G9QMS1_9GAMM/61-455 AC A0A6G9QMS1.1
#=GS A0A1I1JUL6_9GAMM/84-473 AC A0A1I1JUL6.1
#=GS A0A3E0U1Y0_9GAMM/60-429 AC A0A3E0U1Y0.1
#=GS A0A5S9NQ48_9GAMM/18-140 AC A0A5S9NQ48.1
#=GS A0A244CQ63_PSEDV/66-449 AC A0A244CQ63.1
#=GS A0A4U1BLJ0_9GAMM/59-423 AC A0A4U1BLJ0.1
#=GS A0A5C2HMA0_9GAMM/8-373 AC A0A5C2HMA0.1
#=GS A0A254NAE2_9BURK/73-458 AC A0A254NAE2.1
#=GS A0A5S9NQ55_9GAMM/46-155 AC A0A5S9NQ55.1
#=GS A8FXQ0_SHESH/62-436 AC A8FXQ0.1
#=GS A0A7Y0LEA9_9GAMM/63-457 AC A0A7Y0LEA9.1
#=GS A0A4R6PQY6_9GAMM/79-472 AC A0A4R6PQY6.1
#=GS A0A7X0TT42_9GAMM/137-558 AC A0A7X0TT42.1
#=GS A0A2T4CU76_9GAMM/65-455 AC A0A2T4CU76.1
#=GS A0A2T4CSJ5_9GAMM/29-334 AC A0A2T4CSJ5.1
#=GS A0A0F4P856_PSEO7/161-560 AC A0A0F4P856.1
#=GS E0UU17_SULAO/55-436 AC E0UU17.1
#=GS A0A1B7ULE7_9GAMM/74-451 AC A0A1B7ULE7.1
#=GS U1KKA7_9GAMM/63-477 AC U1KKA7.1
#=GS A0A0D8D3Q6_9GAMM/152-561 AC A0A0D8D3Q6.1
#=GS A0A1Q6CDZ8_9GAMM/157-528 AC A0A1Q6CDZ8.1
#=GS A0A396TZA6_9GAMM/61-436 AC A0A396TZA6.1
A0A1H7H9B6_9GAMM/58-429 ...................DLITFTFSqdlD.AAFVAAT--TI..........NATLVGAGGG.D..E.MVLGKLSQ...............................DANS.....VTYRVTSLS-----..................................LGNGATTT.VGATVAIEavtfpgaalraagtatvtySAT.LSNGTTPLDQ..ATGGDta............tatIVDLVDQY......ATSVTTGFDGVIDVEDN.........RETFE----GAAS......ADTVT.....VALVN...T.A.AAD..I.NAT..................................LNTVTY....T..VNGN..FAF............-----...LDTDPVTAGVQLG.TNTVTV.DFG.TVDSVEA..D..KIVVSHNA......................-AVAVTLTIDNVE----.....AGVLPTQTFSV.......DAVV.NYDDNDAAT................HDSAVASHAAGE....WTINGSEVTFPYAPVGY.......dHIVTQFEIA........................NSGN.QDGDIILTAFDTAGNTY........SATLPQKAE.AGKLTKIGFDdVTTAFgLTAG----T....KLSLTITTTAPAGDIKI-..TGYS..NLNDAGR.....................
A0A1W6MHC5_9FLAO/100-261 .........letkidpagg--------...-.-----------..........----------.-..-.--------...............................----.....--------------..................................--------.--------...................---.----------..-----.................--------......-----------------.........-------------......-----.....-----...-.-.---..-.---..................................------....-..----..---............-----...-------------.------.---.-------..-..--------......................----TTYTI-------T....gNSQLLSVPFAF.......HSNT.TSSV-----................ASSSSSPSNSGV....----TTEFLIPYLPYGP........TASQIIYITsyyae.............panrdsNAAT.VSTDISVEAIDNNGNLY........DLGVITSIS.DERVTKLHTL.INNAL.QAAGLTGN-....--QVAIKITASNSNFNLYphAGF-..NVGGNDR.....................
H5TF71_9ALTE/58-486 ...................DLLTFTVT...G.ASLNTATPTLThsnitrtavaDTPTAGAGGA.T..Q.ADVDAAAAgfpsriielgdvvtgitqtlggdltagvlsrTATS.....VTFRVTAVTNNTTGtrl...........................tlggLELTTAST.IDAVGNISv.................aYSA.QTNTGTAIDN..TGTLTd...............vSHTVANQF......TATTTGLLDAVVDVEFA.........RQQFVGNTNVLRN......TDILV.....VTPVT...N.-.---..-.-VDlagg.........................plnaaYTGSTI....T..IAGN..FSW............MDTDT...TPGVSAAELAAAF.NVNVSA.NDT.MVRTINA..TgdLITVVISDea..................ggVVGVPTMTFTNLGAGVG.....RAVLPTSTYTV.......NTTL.RYTTAAAAP...............aTVTLQTNAAAGE....WTLNGAQALYNYVAVGY.......aGLQNTLTLS........................NSGT.RSGAVVLEAFDEAGNTY.......gPVTLANELA.PTSNMKISGDdIIESLnVPAGT----....KLSVGVIVNAPAEAIDF-..SGFT..QVVGTGR.....................
A0A1H4A0K5_ALKAM/3-306 ................fsa--------...-.-----------..........----------.-..-.--------...............................----.....--------------..................................--------.--------...................---.KTNTGLDLDT..GGTNDer............kvdLVKVVSQF......-TTTAPSFARVIDVEQQ.........RRRFTDADAPNGDytvdgqF----.....-----...-.-.NIV..S.LVTggnv..........................yarpITGVKH....T..LAGD..FSWv.........rdTDANT...AGIQPAAGVFVVD.PATCPG.LAN.LT--VTV..N..AVSFECTA......................VAANTTLTIDPEANRTAt...hNPVLPTQTFSA.......TSEV.TYSGPVA--................TGKVFDAVGAGS....WTLNGSSVYIPYMLYGP........TAEQTIQLT........................NKGN.QNGDIFATAVVGGNTLD........-LGKVGTSN.ARTVTSLNAA.IRNAM.VAKGVNLAGpgnfAVGLTLVTNVPEQDVTVY..SAY-..QRGNGDR.....................
A0A4V5NW09_9GAMM/59-442 ...................DLITFTIS...G.AELDTTSVPAT.........iSVAQDATPTP.DliG.ITLGLLNK...............................TATT.....ATYRVTELDSSGLTeapttig....................qqidltgLVVKADTL.G-SKATIA...................YAA.ETANGQELDS..AAKNSg...............dLLVTKTQF......VAAVADDFDAIIDVNEQ.........RLKFSTTSGGAISa....vSDDMD.....ATVTN...N.NsSWL..N.AGT..................................PGKTTF....T..VSGD..FAF............----L...DSDKDTDGVQPAA.GVVTAS.GSP.ASVKYTE..E..AITVEYTA......................FTGAFTLTLDLNGSAGAntdplTSPIGTQEFGL.......DVDV.EFTA-NAKT................ATADVAELDAGA....WELNGAVVHVPFMPFRD........GFSPIVNIS........................NVSN.QEGDIEVMVYYASTEDKk.....peSFMLDVAAA.PEAQTNI---.-TSAL.QKAGIE--G....DVAMDIIVNAPKDDIEV-..NALY..FQ-----ggdr.................
A0A4U1BLU7_9GAMM/59-441 ...................DLITFTIS...G.AELDTTTVPATi........sVAQNDTPTPDlI..G.ITLGLLNK...............................TATT.....ATYRVTELDSSGLTeapttig....................qqidltgLVVKADTL.G-SKATIA...................YTA.ETANGQELDS..SAKNSg...............dLLVAKTQF......VAAVADDFDAIIDVNEQ.........RLKFSTTSGGAIDa....vSDDLD.....ATVTD...NnS.SWL..N.AGT..................................PGKTTF....T..VSGD..FAFl..........dSDKDT...DGIQPAA------.DVVKPS.GSP.ASVKVTE..N..AITVEYTA......................FTSAFTLTLDLNGATANte.alTSPIGTQEFGL.......DVDV.EFAA-NSKT................ATADVAELEAGA....WELNGAVVHVPFMPFRD........GFSPIVNIS........................NVST.QEGDIEVMVYYSSTEDKk.....peSFMLGVAAA.PEAQTNI---.-TSAL.QKAGIE--G....DVALDIIVNAPKDDIEV-..NALY..FQ-----ggdr.................
A0A0A7EEU5_9GAMM/85-499 ...................DKITFNFG...S.TALLKGADFELvl.....adgTGTTIAGSEG.S..V.YGVRISAV...............................DTTNgv.aeVKVRIANAGATGIPag..............................siLALVEAGT.TGTSPGVNsdlgd.........ltltaPGG.TWTSSACVEV..TATDVvgdslpg...atvgntcVLEFSNQFg....lDPASLTDLTAKIDVAQD.........RKTYVEQTTVPTA......-----.....DGEEA...V.A.NDV..T.GT-..................................LSSATY....I..ISNS..ASL............--DDF...ITFDATDTVVYTF.TDTSEW.TAE.DAPTFNG..G..ALSTVTDSpelrty..........tstggfASGTTELVYDVDGTTG-.....TDTLAPHTVSA.......KAVI.NFTDGGS--................NDGLASVSIEGAdlynVGINGSTSKVASFTLNPs.....tsGFFSWVEIA........................NESG.DAADVEVDVVIEGMTYK........-AVKLGSVA.GETVRTIGHAeIQTAL.EAAGATVNAn..aKVTLTFVVTAKEDKVQV-..SGM-..TKGPDGR.....................
A0A4P6VRZ7_9GAMM/87-582 ...................DRIFVTFS...G.TSIDVASLPLSrtg...yiipTAPSVADPVR.G..V.ITIGRIGSt............................vvDGNT....vVEYRVTNVSEGANTqnaqlffgvtpdm.......paagnaisnwttsaFKFNSLAV.K-AAQGVDi................syRAE.YKNNGGVFDT..VGTRRtn.............vaFIRTGNQL......DGNYSGNLTARINTFDHnvaktgnapRQAFV-AGSGQGR......TNEVA.....YGATF...A.A.PDV..T.TATtaanvlvgsvgnrfkfefstvpnatgwnfalknaDIKTAF....T..VAGN..YGHfltannagvvapVNGGT...VAGATSVSVAGAYvPASGQW.GAN.CFNLNGT..T..GGNVVADGnivaptfpvgaaqpaalkfncgVGTDFDFGLAVPGAWTP.....TGVLARQDFNL.......SAVM.SYSGTAG--................SASKTLNRNIGT....WTNDGTTVFVPYMPYGN........GISQLLFVT........................NTGP.AARQIAVDVYTQNHNRAaad.kfkdAHVLNMNVDiQPGVTRLTEH.VRDAL.IARGVWDGAs.sqTFAFDFIVSGDTSEIEIY..SGY-..-NVNQDR.....................
A0A094ITL9_9GAMM/99-558 .vipaaagsynddadaedv--------...-.-----------..........---------N.K..G.ITLDFVAE...............................TADDagntvLIYRVTNIFGDENTnsndtty...................ginldfgrFNFDAPVV.V-AQNGVMfdtfs.........rlddqPWP.TNTNPWPFDT..VSAPMtd............ntqLFKMGPQF......YLDVEEEFEGELDVWDF.........RRTFRTPGASHGN......QDTSSsslfwVRTTD...N.P.DTG..T.LADdnagewdf..................vvqvdsdvEEQIEF....T..LSGDnmFGWids......anpA----...------GLEAVFS.GNSCAY.ISH.-----TA..S..VLNFRCAS......................VDVPTGLLFDLVATMDS....aQNPKQDGEFTIsanvnwtHTTT.QYTDGGATDnvnfpedgvllespayGETSLSGLYAGE....WTVNGSVTHIPYMPYSAqseageivPISQIIYVTnnsrdpgfddavvggpndfdgpapENNN.VDRIIWVEVMEENGDTT........-TFELDALA.NPGVTAIAGE.IRSAL.FNAGMLDRT...rFLSLTVNVADYPTNVSIY..SAY-..NVNGSDR.....................
A0A2S2E0N4_9ALTE/78-457 ...................DLLTITFS...G.ATIDTSASSPElacd..atdtNCSASTGSGD.V..A.GDFSLIDS...............................TTST.....LTFRVTADNSDEENlsy...........................dlsgVTLDSVSG.GAISVSTQ...................-GT.ISGSGTSFDA..GAATT.................VAMVSSEF......SVAAGDSFDGVVDVENE.........RKQFTDGTTDSATldvmwgADLLS.....VSSTG...A.T.LAL..T.GSDlafln........................daegdLDSGSY....A..LTG-..---............-----...---------ATED.TDETTF.ADN.VLSLTTT..G..GLTSGADA......................--IGVTLTADGVNDED-.....AQVLSDQSFSA.......DLTL.NYSRLVGSTv.............etGSMTNDNIDLGA....WTLSGATINIPYIPYGA........GISQIIYVS........................NDGG.VDGDIELTAFDDAGNEY.......gPVTLSVSAE.ADKITALSTS.IRNAL.EAEGYDGSS...kKMDMTLVINSPSDDIELF..TAY-..NVRG-D-r....................
A0A2T4CU89_9GAMM/44-433 ...................DVITLTFT...G.NDALDVDSLPP..........FVTIAAAAPE.K..G.LTIGLISTsv...........................enGTTK.....ANYRVTDITG-GATdtttgi......................ildfgtLDFDSTKS.G-NGINVA...................FSA.VTNTGLNLDT..GGGADrn.............qdLFAIEDQF......EVTVDTALDAVVDVEAE.........REFFT----GPAT......ADSLV.....FTAAE...T.A.AFD..L.SAG..................................VDGINY....S..IAGN..FSW............VQDTD...ANTAGIQPTAGTF.TVTPTGlAVC.GAPTVTA..M..ALSFSCDI......................LD---QITVDIDTAPQG....sDAVLPATTFGI.......DANV.EYSVGA-SA................SDKDLDRVAAGA....WTLNGSETFIPYMPYNRvg....stGISQIIYVT........................NSGS.QSGEISIDVTSADGTVTn.....ltNADLGGILA.APGVTKLTGA.IVDAM.GAKGLLSGGtatkQFALNIVVNDANDVISVY..SAY-..NVNGSDR.....................
A0A6G9QMS1_9GAMM/61-455 drmlveisgntsvtwpasv--------...-.----------Dm........eTVIPSGTPGA.T..AtGVWGLLDS...............................NGAS.....ATYRLTNLDTGSDQlntigsi....................tkftgyeVDVA----.--------...................--D.ILAGGVNFSV..DFKLVdgtnvd....gdkvtkpVATSANQFg...gsSIDASGRADQVVDIEQE.........RKAFV-----TGT......TDVVT.....ITAAT...E.T.PGI..T.WAAstvga.......................dpeiatVENQVF....V..LKGD..FSN............-TTVV...ANGDSLNTVVAAD.KMSATY.TYN.AAG----..-..-------T......................LTTAATFVITPTGA---.....AALKAPQSFTA.......DVSY.EYYNAPIMGsiltggi..latgtlgEFDAGSNLNAGE....WTLNGSIVHVPYMPYGP........GITQIVYVD........................NRGS.QTGSIFVDWYDENGMSGtc....dlSSDYGVMAT.AGTVTKFTGE.LKECIlGDVESDAKT....KVAFTVTVNSPENDITIY..SAY-..NVNGSDR.....................
A0A1I1JUL6_9GAMM/84-473 ...................DLVYVSVS...G.ATFDTTIPPTF..........AFTTAGTGTA.N..F.VDFS----...............................DANT.....ARFRIATADW----..................................AAADLLTI.TGFDLKTT...................-GA.TTATNIKFGA..KAVSVnpligdy...dkavdlsAFTFANQL......-SNVITPLNAEVSTGAG.........RAEFTTTGGHATL......QDVLT.....VATTD...T.P.TAV..D.SIL..................................VTKVTH....V..LTGN..YSWvmdydlaanggdADGVM...DAAEIAKAFTTTL.GAPALG.ADN.VVYTLNT..A..LTTLTATHnvvggv..........lntssgIDASVALQLNAVGNAKS....gSTIFAPQSFAL.......NTTV.SNGT-----................ISYSLPEVTGGK....FTLDGSTTNVAFMPYGA........NYAQSITVS........................NRGS.VVGAITVDIFADGVKHS........-KVLTATSA.ANSVTNISTE.VKDFVaEKFGATFEG....NVSLSIVTNSPS--VEA-..TALY.yAKSDADR.....................
A0A3E0U1Y0_9GAMM/60-429 ...................DIITVTVS...G.ATIVTEDEDED..........----DIVLDD.P..N.GKLEFLGY...............................KDNA.....VRYLVTEAIEEADAeatf..........................vvegLMLNIASA.A-AKGAVKvs..............aagRVD.TVDGAIDVDA..SKSVT.................AYNFVTEL......SSEVTTKFDGVIDVNEQ.........RLEFT----ENGT......ADTLT.....ITNTV...A.A.TDL..G.VT-..................................TGDATY....T..VYGD..FSF............-----...-LDADGDGELGGD.DDGTVT.IDG.EDAKVAD..D..FLSVSLETd...................faPTTAGSATVDVVVTGPE.....DVVIPDQSFMA.......STTV.DYTVSSAADad............efTATTLDKAAAGS....WTLNGAKAHVALMYVGP........NYAQAVTVS........................NTST.QTGGVDVTVYVGGDAVT........-FEGVATAQ.AEGVTDISVA.VRKAI.ADAGITDG-....VVSFDVVVNTPSASTEI-..KALY.fTKSDADR.....................
A0A5S9NQ48_9GAMM/18-140 ....vgshsalsdtskrgc--------...-.-----------..........----------.-..-.--------...............................----.....--------------..................................--------.--------...................---.----------..-----.................--------......-----------------.........-------------......-----.....-----...-.-.---..-.---..................................------....-..----..---............-----...-------------.------.---.-------..-..--------......................-----------------.....-----------.......----.---------................------------....-----SAYVIPYMPYSA........TSSQIIYVSrvp.................aswvGEGKdETGDITVDAIDNNGNLY........DLGVVAQAA.PNSVTKITSQ.ISTAL.ESKGFTGG-....KVSLRIQVENPE-NIFAY..VSY-..N------agsvr................
A0A244CQ63_PSEDV/66-449 ...................DLIYLTVS...G.ATFDVTDTPAI..........VVTTVGTGDA.N..F.IDFA----...............................DANT.....ARFRVSTADW----..................................ATGDTLTV.SGFTLKTA...................-GA.TKDTVIKFAS..KAVSVnpligdy...dkataktAFTFAPQL......-VQTITPLNGEVSTAKG.........RAEFTSSAN----......QDVLT.....VAYTN...A.H.TAV..D.NLD..................................ITKITQ....V..VKGN..FSYvmdydlaanggdADGVL...DAAELATAFTTTL.GAAANG.ADN.VVYTLNT..A..MTELTATHnvvgd...........vtttqgVDASIAIELNNVGYSAG....gSVIKAPQTFTI.......DTTV.SNGT-----................VSYVLPQQSAGA....FTLDGSTDDIELMPFGS........EYAQSITVA........................NTGS.VEGAITVTLKANGSTYT........-KTLDAVAT.ANTVTNISLE.VAAFA.AASGVTGN-....-AHVNVVVNAPAGNIGV-..KGVY.yHKASADR.....................
A0A4U1BLJ0_9GAMM/59-423 ...............dvlt----FEVN...D.GEILGAG----..........----ALSSAD.G..S.ITAGLMNS...............................TGSS.....VSYRITSTNGLNVGk................................pLTLNDLRL.SLKPLQLTer..............qtiS--.----FYNYGY..GGHLVesv..........mgepLLVLAEQF......TAEVSHPLDRHINVTEG.........MREFVGSGT-DKH......QDQLQ.....FVLRK...Q.P.KQTfdQ.LLHp...............................aeGRRVQV....L..LQGN..FAF............-----...----LGKADQYGE.IVGAES.HFS.LSPTTAS..E..RLQVFRDHlliel...........dsrelaPEQTMTLTVDIAKSGEEq...aEAPLSSQEFSA.......KVIQ.DYIEFDGFSl.............ekTENLAMGQNWGA....WQSSGAHFIVPFLPYRE........GMSVSVVVS........................SLSS.RQLPIMAKIYFSDGRAP.......lVIDSLAEIQ.PNTILDLEPA.LSELA.LS-------....------------------..----..-------ddvaiellideephlisvhsq
A0A5C2HMA0_9GAMM/8-373 ..................w--ITFTLS...GnCTFDGSYYLAF.........nNANNVISYKN.A..K.QPFDVLSS...............................TSTS.....ITFRVADDTAENAVpasalaagnvyyltsgtadmdgnddnavdtgaptI-------.-------Kltgltd......gsscnlaVGA.KTSTNLVLDS..NTGDVks.............vkVAEAKNQIt....aTVNTATDFDGVIDVQATp.......gSSKFTGAATTDTAvi.kiiSDAGS.....V--IT...D.A.LDM..E.FT-..................................NGSTDYklkvT..VKGD..MTN............--ITS...ISDGTNTYTIDAA.NNMAYI.EYT.ESQLHTL..N..NATFGDTD.....................nEQLDITLTATVNG----.....TAALETRNFTA.......SVNV.IVGTA----................SFNNATDVAAGS....WSKNGSTAYIPSWLTNAst...dttNYQTYLRIT........................NPTS.TAGKVYIKGTADDGTAT........AQCDVSTL-.----------.-----.---------....------------------..----..-------agvtgfts.............
A0A254NAE2_9BURK/73-458 .................rf--IRIDLT...G.AKLAVAAAGAD.........vTNTTAAAAAN.N..F.QNVAVVQGg............................gvGDAY.....VIYQVTGAAG--GH..................................AATDLTTI.VLPNLNVT...................NGN.ASAVNVTYAL..YADAVaaanqtagqslstqsgaLFTFGTGI......KFKVTTKT-ATATVADS.........YKKFSGSYG-PVEv...gqFDYGT.....TGAFD...A.T.GAA..A.TLAs...............................lvGANTKV....A..FTGD..FTF............---TQ...SATTATNLRLGDT.GTCANG.VAL.TSIATNMlsA..SYTLGTTA......................INKSLCVTNDTVTNTT-.....PVALTAQTFSV.......DFNP.VNSSAGTGS................TVTDPAATTLGA....IARDGTTLTAPFVTIHP........DYLSRVVLN........................SSYG.ADAAVTASVTAENGVTC.......tTSGYSTTLK.AKSQLVINVKdICPAL.SNAGT----....RLAVTVTVAAPRTNID--..----..-------gvynvmnydvtt.........
A0A5S9NQ55_9GAMM/46-155 ...............cday--------...-.-----------..........----------.-..-.--------...............................----.....--------------..................................--------.--------...................---.----------..-----.................--------......-----------------.........-------------......-----.....-----...-.-.---..-.---..................................------....-..----..---............-----...-------------.------.---.-------..-..--------......................-----------------.....-----------.......----.---------................------------....--------IIPYMPFSV........NSSQLFYAAnvpn................awsgATSS.PSSDISVDVIDDQGTHT........SLGQVAVVA.PQQVVKLTTP.ITQAL.DAQGVTST-....KLALRIQATNPE-NLYIY..SAYQ..TAAD---ra...................
A8FXQ0_SHESH/62-436 ...................DKVTYTFD...A.GALDTTNVFPA..........QINVAAVTGR.A..G.MALGLLNQ...............................TADT.....VTYRVTSVNQFGTEtgkttlga..................tivltpttAALKATAV.AGGTINVT...................VSS.ETSTGDDLDS..SSSTNasr...........tgpLTLVKTQF.....gKISVGTELDGTILVAKN.........RKELD---NGNVD......SMVYS.....ISQIT...T.T.GWQ..Q.LVT..................................NNGTVA....T..LKAD..---............--LAG...WDLTKSIGSIGSS.AGGTAT.YDD.AKKEVTL..N..YGTNV---......................-ITTDTVTLTPPTGTK-.....AVVLLAQDFEV.......AASY.AYTH-GTST................GSASVGTADAGE....WTLDGAVVNVPYMPYAD........SITQIMYVT........................NEGS.LDADVSVMAFDEAGNDY........DLGVVAVSK.AGTVEAIAGA.VQTAL.EAQGFTKG-....KVSLTVTVNAQDKDISIY..AAY-..NVGGVDR.....................
A0A7Y0LEA9_9GAMM/63-457 ...................DIITFTFA...G.ATLDVAT-VPG..........TLTAVNGTND.L..D.VTVGLLSA...............................ADNV.....VTYRVTEVKDNGNAtlqstvl....................atftisnLEFDTATVlANAKTTVT...................YAA.ETSTGVTIDA..GTKSSg...............dMITTQKQFs....vDRSADSDFDAIIDVEEQ.........RLQFT----DNDV......VDLVE.....ITLVD...D.A.GTT..DfNAT..................................AATFDI....V..LNGS..FSY............-----...LDTDANTAGIQTT.GITTSS.GAI.AAADILA..D..TVTIKGAA......................-AGTVTITIDADAGAPAa..fsEAVIPTIDYTA.......TITV.DYTDSGT-Dgagt.......gaaagEATVVTGEDVGE....WVLNGSVIEVPYMPMGP........NTQPFLRHT........................NDGS.QSGDITLRYMVEGVDTEy......tDSVTLVEDA.APGVRNLLNE.IEAAL.LADGYDRSAa.gfKVALEITSNVPADDVKVT..TGAKfiNQENTDR.....................
A0A4R6PQY6_9GAMM/79-472 ...................DRILIEVS...G.AQFTLDADTIFg.......deAVGNLTKDGA.T..V.GSFTPQLQtlnslals..............fdagenfttT---.....------------ATpgdsmvn....................velrnlkLDLDGAGL.G-DNVQVT..................vKAQ.KLLGTNNFTTvsQASGT.................VAEVVSQLglntfsGTSISTRYSGETINATN.........RLSFTT---GSAL......ETTLG.....LSLQDrgvN.Y.ASV..E.AVS..................................GGEYAM....T..VTGD..FGF...........lDADGD...GELDEGVAVTAGT.GDIEFA.EDF.SSFVVTN..S..AAAISGSG......................SNVNQDVKIELDGEREIp...eLSATGTMAFNY.......QTVL.PSNT--AIG................GGTFEESALVAS....WALQGVTTTFSYMPYGP........SISQILFVT........................NNGY.NDGRITVSGWDEAGNKY.......gPVTLDKVAT.ARGVTKVTGE.VEQAM.LAEGFSGRG....ALKLSITVNTSS--AEVY..GAY-..NVGGADR.....................
A0A7X0TT42_9GAMM/137-558 ..................s-TLTIDIQ...G.AKVDLTKTVAP..........FLTYNVNGTG.P..F.-NVPVLDI...............................TENT.....VRFTVPVGQD--IPplav.........................itirdVFLSATGL.TGTT-VVDi.................kSKA.TNTAGLDYDV..TDWTP.................VLELKPQY......SAAVSRKFDAIIDVTEK.........RQSLVPNTI-P-SlidaldQDTFV.....LKVTQ...E.V.TAG..V.GAElaa............................tggKLSITS....Q..ETGG..FGWmd........tdGDGTI...TAAEIAASAMLTT.TATAGA.DTL.FAGTLDA..T..NTILTYTTsadgsptptp..sqtldleyqlVLDTTALHAAGIGNPLSp..yaEAQMFEASFSA.......FSTApTVKEMKACD...............aATGAVCDLDAGE....WVLNGSVLTVPYMPFGD........NTQVILRHT........................NTGD.QDGKISIRYMIEGSAGNtadtawvaIPTPLATPS.VGGVLDIKNE.VMDAImAHAGTTRG-....KVAIEITTEAPEGDITVY..AAYK..VLSEQDR.....................
A0A2T4CU76_9GAMM/65-455 ...................DVITLTFT...G.GDALDIDSLPP..........FVTVAAAAPL.K..G.ITVGLISTsv...........................gnGTTK.....ANYRVTDITG-GATdtttdv......................vldfgtLDFDSTKA.S-GGINVA...................FSA.VTNTGLNLDT..GGGAArn.............edLFAIDDQF......QVEVSTDLDGVIDVEDE.........RQTFV----GAVT......ADQLV.....FEASE...T.A.VFD..L.AAD..................................VDGIDY....S..IAGN..FSW............VQDTD...ANTAGIQATAGTF.TVTPTG.AAVcTAPVVTA..T..ALSFSCDV......................LD---EITVDIDTGPQG....sDAVLPAGTFGV.......DANV.QYSFVGGTD................SDKDLDRVAAGA....WTLNGSETFIPYMPYSRdn....msHISQIIYVT........................NSGS.QSGEISVDVTAADGTVTn.....lsNADLGGIVA.APGVTKLTGE.IQSAM.IAKGLLTGGsstkQFALNIVVNDANDVISVY..SAY-..NVNGSDR.....................
A0A2T4CSJ5_9GAMM/29-334 ................dvm---IFSFS...G.TDSLDITSLPTf........lTLAADGINGK.K..G.MTVGLLAQe............................rvNGRT....lIYYRVTNITG----..................................--GESDTT.TGITLNFGsidfeslr...aqngidviFTA.RSNAGFPLDN..FTTDQns.............qvLIEATEQF......LTTVTQPLDQEVDFNND.........RLTFL----AGVT......SDVLE.....FRIEN...D.P.TLD..I.GVD..................................VDDVAY....E..ILGD..FSW............VKDQSpglVNIQPAAGVFT-L.TDLSGT.AGC.SNLLVTA..V..SLRFTCDT......................LD-TFTLTIETAAQGS-.....DVVIPTNEFSI.......LADI.DYSVVGGTF................NASEVGPVDAGA....WTLNAAQTFIPYMPYSReg....lnQYSQIIYAN........................N---.-----------------........---------.----------.-----.---------....------------------..----..-------.....................
A0A0F4P856_PSEO7/161-560 ...................DTITVNLS...G.AKVDLTKTTAPt........iTVGNDGLSTA.P.vN.FSFDILDI...............................TAER.....VRFTVQTVNAKNDFvkgga.......................vlqlggIFLDSKGL.S-SDTAVSv.................dSFA.TNTSGTDFDV..ASARV.................ITTLVNQY......TASVSSLLDAAIDVGKD.........RQEFA-----TGT......SDALV.....VAMKK...N.T.DNL..E.LT-..................................PAEVHY....T..ITGD..FSWmlddd.idtnkdGKLSS...AELGKAVKVAGLT.DDAAKS.YAV.NTELTKL..T..VVSTVTGA......................VDTSATITFTVPGHDEGk..leNLMIPVQDFTV.......AVDV.KDNKAFSTAa..............vNMPALSATNAGA....WTLNGSVVIVPYMPFGP........NTQPILRHT........................NAGT.RTGDITVRYMVEDEHNAwqp..laaAGVKDAKPG.VRNMLNI---.VTDAL.KAEGYDSEKs.gfKVALEIVTNVPSRDVHVY..GGAK.vDVDGQDR.....................
E0UU17_SULAO/55-436 ..................p-ALNAAIS...D.GTLVVEY----..........---TNAYSQN.C..D.ANTSELVMydgtkyvtk.............anptcggtpTGTK.....LLFDVNNTIADGAHl...............................tlVDKDTNTT.S-GDLNVSilkga.........dvasvKFSlVNVNDVTVDP..SSGSV................tIATGKTEW......SAAVGTSFDNQIDAAKS.........FALFTNSPATNDD......-----.....-----...-.-.---..-.---..................................NATITF....T..RTT-..---............VDFGG...ATLDANIKLTTDY.NVSSIG.SLK.FNNVVKT..P..NGSFVYDVna.................tglLAASTDYPIDFDGNTTTt...sGTKIDATGFKV.......AVSA.VKLGTAAYS...............kSYVSASDKNLGE....WSVYGYNGYVPNATASTa......sNIETVLSFT........................NTSS.TTVDAYFTLVAADGTETqv....dsVNDGLAKLE.TKKTVKYNVSdLITTAgVAEG-----....--SYMIKVVFPTTPSKIIgfASFR.nDNKNAF-k....................
A0A1B7ULE7_9GAMM/74-451 ...................DTITFTFT...G.GLKTAPL----..........---SITSSGA.N..A.VTLGRTGQ...............................TATS.....ATYRVTEITGAGAVhgsftf......................tgatalVFKGADVV.ALGKVNVTyga............tlgtSTS.ALDTPVEYNA..DADLTs..............gaLFNVRDQFv....aAVTAVNRFDGVLDVAAD.........REAFT----GAVT......TDVLT.....IGLTN...N.S.GDT..S.AVA..................................KGTTTF....V..VNGD..FSW............-----...-----AEDATVAA.PVCTAG.AVV.GTPAITA..T..SYTFACNA......................ATTGATLTLDIDQGAD-.....TVAVNPTSFSL.......VATH.GYGAST---................ASLTQAALNAGA....WTVNGSVVTVPYMVYGTvg....ekLFSQVVNLT........................NNGS.QTGTIYADVWATDAVTGksv..pvlSNVTVGTSH.PKATAKLAGV.IRQKMaEAATPFING....TVAIRLITDVKADSVSVY..SAYV..DNATSER.....................
U1KKA7_9GAMM/63-477 ...................DRIKLTFG...A.GLDFNQTGTAAfsgv..tlfnNSTTATTLPA.A..G.VPTGVLGI...............................NTGS.....GTYELEELTALRDLangvvvlevktgf.......tieqdesfevipdvVLFDSKAT.T-ANATVT..................ySAT.RWQDGNPKDT..TGDNTg...............sFLKFADQY......AAAVSTKLDGVIE----.........RENQVTFISGFVTad..nvADTLK.....VAITD...N.S.TYI..A.AATg................................aNVSADF....V..LTGD..FSDl..........vVGDFT...AVADAGANFATGD.IAIALA.GDK.KTATVTV..S..DTAASDDG......................IAGSFTLTIDNATRTGAt...tPVTIKATSFTV.......KGDV.DFDGAGTIT...............dASVLAAGTDAGQ....WVLDATIINVPYFPVGF.......eGVNSQVNFA........................NEGS.AAVDVNVTAIDATGTQY........-SGSLTDLA.KYSTTKVSQTtLQAALkDSKGNTVPDg..sKLSVTFNIDADDGKVNAY..A-FS..EKVGLGR.....................
A0A0D8D3Q6_9GAMM/152-561 ...................DTITLTFS...G.AKIDTTLTVAPt........vTVSGDAGVRD.T..G.TAATFIGTaadmtf..................dlldidpDGEF.....VRFTVKSADSATTTvapna.......................ilnvagIFLDSTGL.S-SATSVAm.................sTVA.INTSGTEYDP..SSAAT.................IVSLTPQY......EATVTTAFDALIDVGDD.........RQGFENSA----S......ADALT.....LNVDK...L.T.TGL..E.LT-..................................PEEATY....V..ITGD..FSWmldds.idtdesGTLTS...AEIANAVTYAG--.-DTLKS.YAI.DTDLTEL..T..VTTTTGAA......................VTATQVFTFTVPGYDNGa..meHPVINVQDFTV.......KVDV.QDDDAFTTDp..............vNMSANLITDAGE....WDLNGSVIYLPYVPFGP........NTQPIIRHT........................NKGN.QTGDLTVRYMVEGVDTSwna..lsaANVDDATPG.VRNMLTL---.ITDAL.KDEGYDATTd.gfKVALEFVTNVPSEDVFVY..GGAK.vTAEGQDR.....................
A0A1Q6CDZ8_9GAMM/157-528 ........altiapgvagd--------...-.AKAAVAAANEI..........---VIGDVGA.A..V.ADLVDFGE...............................DANGdy.ewVLFKLTTATAADAV.................................lVFNDTDGD.HAANVVTKftkatig....agdltvglPEA.KDDTGT----..----Vlaapv.......aeaktLVTTENQF......-ALTATAVTDTIDVEQD.........RLFFSDAIGDDVT......TDFVF.....DITVD...G.T.IDL..G.ID-..................................HTTAEF....AmeLTGN..FTG............----V...EQA--------DY.TETDIV.GTN.DTAVFDA..D..NMVEGVGI......................SDATVAITVDGDT----.....--NLATRTVKA.......SMMI.TPTEADT-N................AFYLLGSSSAGAnafiWDLNGSEITFPYAPIGY.......dHVTTNFELA........................NSGD.QTGDVLITAFTREGVAY........SGTLVGKAE.AESLTKISEAeVYDALmLTEGT----....SLSVTFSTTAPDADIKI-..SGYS..NLASGGR.....................
A0A396TZA6_9GAMM/61-436 ...................DLLTFSLS...A.GSVADSFDALP..........-ASIVANSGS.T..S.ITFGKLAT...............................LADS.....VIYRVTNVDNPDLLgttgiv......................vdfaagIDVDGDVI.A-AGTNIEl................caTAT.TAVGGITFDT..DCMD-.................VAAVEDQF.....tNVSVTTGFDGEIDVTNM.........RETFT---GANTL......EDTLV.....ISHTTe.dT.T.GWA..S.YVD..................................PGIVTL....V..LKGD..FTD............--LTE...SQFTSGATTTDLN.DDENEL.TLT.YPSTLTT..D..TITFTSDG......................--------------TGS.....GVSLIKQSFEL.......DASQ.SYTCGAGCSgd............adVASLGMGTDAGE....WTLNGADINIPYMPYVDlelsnserAIGQIIYVT........................NHGS.QSGDIFVTATAEDGTVV.......lNNVQIDSID.GGEMRKIAPL.IRDEL.LAEDFTDG-....KLSIDVTVNAADEDITVY..AAYK..HNTEADR.....................
#=GC seq_cons ...................Dhlphsho...u.uphssst...............hssssssss.s..s.hshshlst...............................ssss.....spaRVoshss.t.h.................................hl.hssssh.s.sshsls....................ss.tsssuhshDs..sussst...............slhphtsQa......tsssssthDuhlDVtpp.........RppFs....ssss......tDhls.....hshss...s.s.s.h..t.hss..................................sspssa....s..lsGs..Fua.....................sht.ssshhss..ssssts.sss.ss.hhss..s..shshssss......................hssshslTlsssssst......ssslsspsFsh.......sssl.sasssss.s................sssshsshsAGt....WsLNGosshlPYMPaus........shspllhlo........................NsGs.psGcIplsshspsusst........shshsssss.spslsplsst.lpsAl..stGhp.t.....plulslslsssssslplh..uua...shsstsR.....................
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