#=GF ID Sporozoite_P67
#=GF AC PF05642.15
#=GF DE Sporozoite P67 surface antigen
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_8657 (release 8.0)
#=GF GA 28.90 28.90;
#=GF TC 29.30 29.10;
#=GF NC 28.20 28.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 10024569
#=GF RT Linear peptide specificity of bovine antibody responses to p67
#=GF RT of Theileria parva and sequence diversity of
#=GF RT sporozoite-neutralizing epitopes: implications for a vaccine.
#=GF RA Nene V, Gobright E, Bishop R, Morzaria S, Musoke A;
#=GF RL Infect Immun 1999;67:1261-1266.
#=GF DR INTERPRO; IPR008845;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of several Theileria P67 surface antigens.
#=GF CC A stage specific surface antigen of Theileria parva, p67, is the
#=GF CC basis for the development of an anti-sporozoite vaccine for the
#=GF CC control of East Coast fever (ECF) in cattle. The antigen has
#=GF CC been shown to contain five distinct linear peptide sequences
#=GF CC recognised by sporozoite-neutralising murine monoclonal
#=GF CC antibodies [1].
#=GF SQ 12
#=GS Q4UCF0_THEAN/320-454 AC Q4UCF0.1
#=GS A0A830HYA6_9CHLO/40-250 AC A0A830HYA6.1
#=GS A0A0Q9YV25_9COXI/86-333 AC A0A0Q9YV25.1
#=GS B4JLF1_DROGR/276-632 AC B4JLF1.1
#=GS A0A6L2PLV0_COPFO/390-647 AC A0A6L2PLV0.1
#=GS Q27040_THEPA/1-144 AC Q27040.1
#=GS A0A5N5DBX6_9PEZI/21-377 AC A0A5N5DBX6.1
#=GS J4C3Z5_THEOR/890-1066 AC J4C3Z5.1
#=GS Q27040_THEPA/141-300 AC Q27040.1
#=GS Q4UCF0_THEAN/450-917 AC Q4UCF0.1
#=GS Q4UCF0_THEAN/1-259 AC Q4UCF0.1
#=GS Q27040_THEPA/297-709 AC Q27040.1
Q4UCF0_THEAN/320-454 ...............................kpg-------------------------------------------------.---------------------------------------.--QP..................VSQELELKSDTEINES--GSSSEGED.DDDEEEEEENKSTSSKGAGGkAGKG.QGSVSPGGGSSASQTSPTTT-PQSGLA.....SSGSHaq.......qsPQQDPAPSKP.SG.........GGVPGVG.VPG.VGVPGVGv.pGVGVAPGV.GVV-------.-----.----.......-----........................................................................................................................-------------------------.......................-----------------------------------.---------------------------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pgvg..................................................................
A0A830HYA6_9CHLO/40-250 .................sialaeklragflredr-------------------------------------------------.---------------------------------------.----..................----ERMQQSTKEERASDDDDDDDDD.DEDDDDDEDDVSDSDSDYSV.QRKR.QRVGAGAGGRTAVPRRAAAPEQRRGTA.....AAGGG...........A----GGGIA.AA.........GGGAGAG.AAG.GGAGGGA...GGGASGGI.AVAPPRVGAG.AGA--.----.......-----........................................................................................................................-------------------------.......................-----------------------------------.---------------------------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pplsaafrqfmmpeasaqaaaagllpadpipefmpieealkveaefsideydattedemqravnkfancg
A0A0Q9YV25_9COXI/86-333 ltpndakdfqlvsaslahvnkkykavdltakvak-------------------------------------------------.---------------------------PSVSSEEEVSPS.KDAS..................NEDSKDASKDASKDASKDASKDASKDaSNEDSNEDSKASKSASEEKS.SAKE.EPAKKDEDKKTEENKAEDAKKADEKKDedtqkASSSY...........VTAASAVAGV.GI.........V-ATGFW.FSG.F-YPSAV...ALLAKAGL.TIPAAAVAAQ.VGVSL.AVGI.......AVVGVlalgyy............................................................................................................gisklfG----SSEVPATDEKTKEVENRT--.......................-----------------------------------.---------------------------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------edqkyhddlkakqdltakla..................................................
B4JLF1_DROGR/276-632 ........................rhsdnlrshn-------------------------------------------------.-------------------------------SSSSVTSStYKSH..................SQQQMQQQQQHQQQQQHHHSSQRRSH.D-ERVRRRRDSRTRSRSGSR.SRTR.TPI-DTPPLRRRQGQQSTRKYRRRESC.....DSSSRsrspverppvhVRK-------.-PsdvdphtrvYSTAGLL.QGK.LTLPSTA...AVSAAAAL.NAAAISA-AG.SGVGG.-GGV.......GGGGGllptpnyapkipslmslelnappsvlidgppa.......................................................avqlpkyynpgivnanryaeqqqkrkliwgskkNEDSANKWGNAHFSQDS--DGKVAS.......................KFMRLMGIKNANNTNANDNSTNSSSSTTTTTCAVN.TSNS---GSSHSNAAAR-TDAMNEPSTSNGN--------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------asgsnsascvapvpadvqlrqrmfsnmeqqyev.....................................
A0A6L2PLV0_COPFO/390-647 .............................spgqg-------------------------------------------------.---------------------------------------.----..................--------------------------.--------------------.----.---------------------------.....-----...........-------GVP.GQ.........GGYPGQGgAPGqAGVPGQGgypGQGGSPGQgGVPGQGGYPGqGGSPG.QGGV.......PGQGGdpgqsspttpdtaisstpntpggtsassnictsegffpessnckkffrcvdng..............kgaftkydfacgegtvwdpesnacnhnwavqrkdcrirehengagsiseqknnT-----------------------QtttptsvenqksthtpggstfssPSITTSSSSSSSSSSSATTQSQSSSSTSTSSSSSN.ESNQESTTSS-GSGGQTATSS------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gtgsas................................................................
Q27040_THEPA/1-144 ..................................MQITQFLLIIPVLFVSAGDKMPTEEQPFPSRLGPLVTLESAITQPTAVYtMRTVGNVAKAAKAWKSAVSSSDVSTTIPTPVSEENITST.LQTQteevpaasgsdsytvtnlVQTQSQVQDNVKQQQDTKGNRSDSEE.ENEDS---------------.----.---------------------------.....-----...........----------.--.........-------.---.-------...--------.----------.-----.----.......-----........................................................................................................................-------------------------.......................-----------------------------------.---------------------------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------tl....................................................................
A0A5N5DBX6_9PEZI/21-377 .............................pttta-------------------------------------------------.---------------------------------------.----..................------------------------DA.DDD---DDDDDHTTSTSIPG.ASVG.TIAISIYSGGSATTTITLATATVTSIS.....GSGGT...........GGASAALTRTvTA.........VGTPGVS.GNG.TATTTSA...-SATATGS.GSGSGDGDSG.GGGGT.GGGLsqaakigIG--VgvplgvllllaivwgaymlgrhrrrpnssssspsspsdrgggilalltgnrrrrgrrlradsslsspdgreleedaekamlklagpaeletgpdrpelptavncqelaagdpfeqrrvfeEQQSRRREGQQEGQQQEEEGDRQQQeplvqe...........rlakelNGVGIAAGALEAAAGDRRRRRVSSVSTNRKPVAKA.AASRGNGSDGGGSGSARGSYSSYSPIS------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pvgtgsqshhte..........................................................
J4C3Z5_THEOR/890-1066 ...........................dikcfdy-------------------------------------------------.---------------------------------------.----..................--------------------------.--------------------.----.---------------------------.....-----...........----------.--.........-------.---.-------...--------.----------.-----.----.......-----........................................................................................................................-------------------------.......................-----------------------------------.---------------------------------------..........-----------------------RKNDPFKLRFYMFKGIFRLWRLLQDLKFFMVVDHTLITDTFDKGVQNYLTKgLTLMNGIVVRDNGDLLAMYNGFNKYYKAMASRLNHMKEQEEGSEIMKTIVSMSVIGYSTALRLEQEFgswDLVEVRENEENKEGRVASyTLLGFRIAMYLTKDIVEVIMD-------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------kflrytdl..............................................................
Q27040_THEPA/141-300 ..............................dstl-------------------------------------------------.-------------------STDVSPTIPTPVSEEIITPT.LQAQ..................TKEEVPPA-DLSDQVPSNGS------.---DSEEEDNKSTSSKDEKE.LKKTlQPG-KTSTGETTSGQDLNSKQQQTGVSd...lASGSH...........----------.--.........--SSGLK.VPG.VGVPG--...--------.-----AVSPQ.GGQS-.----.......-----........................................................................................................................LASNTSREGQAQHQQVRDGDGRVIE.......................PKIGLPG----------------------------.---------------------------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------ppsa..................................................................
Q4UCF0_THEAN/450-917 ..................................-------------------------------------------------.---------------------------------------.----..................--------------------------.--------------------.----.---------------------------.....-----...........----------.--.........-------.---.-------...--------.----------.-----.----.......-----........................................................................................................................-------------------------.......................----VPGVG-GATTSSSSTTSTSTSTTTTTTTSSGkPSNQGSHGTSPRNAVTRQTDSISGPIPSPGDPRAITGQMgllyssksfvGEGERFAVQFLGDFKPKPRRYEGQGTDAVKLKQFIFEEVKSLVQTLINLKLAIANDFVEISEKLKKKNQNYVPK.LKLLKGEQFDTKQKVANVLKGFNSLYFVFFMNLNLAKEVNKPEELAEFLWKLNTIPDKVGREFELAI...EKTKGSEKKKELEEAFNS.IGLGFKIAQYATNDILSSITNSVYSLIKLKNFGDDFVTEVRKSLQMVPHQKNLNGSAFIVKISEIINKKGTEDQDQTSGSGS..............KGTEGGSLRGQDLTEEEVLKVLDELVKDVSEEHVGIGDLSDPSSRTPNAKPAELGPSLVIQNVPSDPSKVTPTQPSNLPQVPTTGPGNGTDGTTTGP-----GGNGEGGKDLKEGEKKEGLFQKIKNKLLGSGFEVASIIIPMTTIIFSIVH......................................................................
Q4UCF0_THEAN/1-259 ..................................MNIIHFLLTIPVIFVSGADKMPAGESSRTSKPSPLVTLESAVTQPSKDP.FKTISALSKATKVWKSAVSVSGDSKTVPTPVSEPMITRS.FQEP..................VSQELEFQSDTEINESGSGSDEDEDD.DDDEEEEEDDKSTSSKNGKG.SPKA.QPGVSSSSTSSASPTSPTTTLSQTGLG.....PSGSH...........AQQDPGVGVP.GVgvpgvgvpgVGVPGVG.VPG.VGVPGVGgvpGVGVAPGV.GVPGVGVAPG.VGVGAdSSGL.......PGSGG........................................................................................................................L------------------------.......................-----------------------------------.---------------------------------------..........--------------------------------------------------------------------------.-------------------------------------------------------------------...------------------.----------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gagakagkgq............................................................
Q27040_THEPA/297-709 ................................pp-------------------------------------------------.---------------------------------------.----..................--------------------------.--------------------.----.---------------------------.....-----...........----------.--.........-------.---.-------...--------.----------.-----.----.......-----........................................................................................................................-------------------------.......................-----------------------------------.----------------------SAPVPSPGAPGIIVRES..........GNRAMDIVQFLGRFKPEPRAYEGERTNVAELKKFLFEELESLVNTLIELKLAIASDFVEITDGLRKNTKDHEAR.LKLLRGVEFTKRKSVANVVKGFSSLYCVLLMNMNVIKEKTKESEVADGIWKLSTIPDKVANELLLAM...EKIVVPPKTPELEEAFEA.IEFGFKIAYYATKDILSSIENTVHNLMHAKNYEENFIAQVRNSLRMVPHQMNLTESSFVIKISDMMRRRGTASQDEPAGAGSgvtpgrgssgtgraAGTGGGSLRGLDLSEEEVKKILDEIVKDPSDGELGLGDLSDPSGRSSERQPS-LGPSLVITDGQAGPTIVSPTGPTI------------AAGGEQPPSAPNGTATGPAGTQPEGGEKKEGLIQKLKKKLLGSGFEVASLMIPMATIIISIVH......................................................................
#=GC seq_cons ................................................................................................................................................................................................................................................................................sG....st.h.hss........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ss.t..................................................................
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