#=GF ID Stap_Strp_tox_C
#=GF AC PF02876.21
#=GF DE Staphylococcal/Streptococcal toxin, beta-grasp domain
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE Prosite
#=GF GA 22.60 22.60;
#=GF TC 22.60 22.70;
#=GF NC 22.40 22.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Enterotoxin
#=GF WK Enterotoxin_type_B
#=GF CL CL0072
#=GF RN [1]
#=GF RM 1436058
#=GF RT Crystal structure of staphylococcal enterotoxin B, a
#=GF RT superantigen.
#=GF RA Swaminathan S, Furey W, Pletcher J, Sax M;
#=GF RL Nature 1992;359:801-806.
#=GF DR INTERPRO; IPR006123;
#=GF DR PROSITE; PDOC00250;
#=GF DR SCOP; 1se3; fa;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF SQ 46
#=GS A0A075M4C7_9CAUD/176-284 AC A0A075M4C7.1
#=GS Q2FXX5_STAA8/127-232 AC Q2FXX5.1
#=GS A0A4D6B8D8_9CAUD/152-258 AC A0A4D6B8D8.1
#=GS A0A4D6B9C0_9CAUD/127-234 AC A0A4D6B9C0.1
#=GS A0A4D6BA83_9CAUD/135-255 AC A0A4D6BA83.1
#=GS A0A4D6AFU0_9CAUD/135-255 AC A0A4D6AFU0.1
#=GS A0A4D6B673_9CAUD/157-257 AC A0A4D6B673.1
#=GS A0A4D6B5F2_9CAUD/132-236 AC A0A4D6B5F2.1
#=GS A0A143PA80_9STAP/142-243 AC A0A143PA80.1
#=GS A0A4D6B6Q1_9CAUD/132-236 AC A0A4D6B6Q1.1
#=GS A0A143P8S7_9STAP/158-249 AC A0A143P8S7.1
#=GS SPEC_STRP1/127-234 AC P0C0I5.1
#=GS A0A097PAT7_BPT12/145-249 AC A0A097PAT7.1
#=GS SSL7_STAA8/138-227 AC Q2G2Y0.1
#=GS A0A4D6AS46_9CAUD/157-257 AC A0A4D6AS46.1
#=GS A0A4D6AH02_9CAUD/132-236 AC A0A4D6AH02.1
#=GS Q2G2X8_STAA8/143-229 AC Q2G2X8.1
#=GS SPEG_STRP1/126-232 AC Q9X5C7.1
#=GS A0A4D6ADZ5_9CAUD/145-249 AC A0A4D6ADZ5.1
#=GS A0A4D6AFP8_9CAUD/127-234 AC A0A4D6AFP8.1
#=GS SSL10_STAA8/134-226 AC Q2G2X7.1
#=GS A0A068A244_9CAUD/147-255 AC A0A068A244.1
#=GS Q2FZB1_STAA8/143-232 AC Q2FZB1.1
#=GS A0A4D6AF66_9CAUD/127-234 AC A0A4D6AF66.1
#=GS Q99QN1_STRP1/123-230 AC Q99QN1.1
#=GS A0A098M2Z8_9BACL/2-83 AC A0A098M2Z8.1
#=GS A0EX09_9CAUD/147-255 AC A0EX09.1
#=GS A0A4D6B871_9CAUD/43-143 AC A0A4D6B871.1
#=GS Q2G2X9_STAA8/138-230 AC Q2G2X9.1
#=GS SPEH_STRP1/132-236 AC P0C0I7.1
#=GS A0A4D6B8Y4_9CAUD/157-257 AC A0A4D6B8Y4.1
#=GS A0A4D6AEG5_9CAUD/152-258 AC A0A4D6AEG5.1
#=GS A0A4D6BB07_9CAUD/127-234 AC A0A4D6BB07.1
#=GS A0A4D6B7F8_9CAUD/152-258 AC A0A4D6B7F8.1
#=GS A0A4D6B9P3_9CAUD/1-84 AC A0A4D6B9P3.1
#=GS A0A4D6BEC5_9CAUD/132-236 AC A0A4D6BEC5.1
#=GS A0A1X9H080_9CAUD/147-255 AC A0A1X9H080.1
#=GS A0A4D6B6I3_9CAUD/132-236 AC A0A4D6B6I3.1
#=GS A0A4D6BCG1_9CAUD/127-234 AC A0A4D6BCG1.1
#=GS A0A4D6AH92_9CAUD/145-249 AC A0A4D6AH92.1
#=GS A0A4D6B8H9_9CAUD/152-258 AC A0A4D6B8H9.1
#=GS A0A4D6B406_9CAUD/152-258 AC A0A4D6B406.1
#=GS Q99ZZ1_STRP1/101-221 AC Q99ZZ1.2
#=GS A0A4D6B6B9_9CAUD/127-234 AC A0A4D6B6B9.1
#=GS Q99XW1_STRP1/125-232 AC Q99XW1.1
#=GS A0A4D6BA66_9CAUD/127-234 AC A0A4D6BA66.1
A0A075M4C7_9CAUD/176-284 ..............................KKVPINLWIDGK...QNT.V...PLGTVK...TNKKEVTVQELDLQSRH..YLH..ETYNLYN.......TDafN....GKIQR.GLIEFHPSSGDS.VGYDLFG.AQGQY..P...D..TQLRIYRDNKTIKSKNM.HIDIYLY.........................
Q2FXX5_STAA8/127-232 ..............................KNIPCNLWIDGH...QTE.I...ELTAVK...TKKKIVTIQELEVQLRN..YLN..EKYKLY-.......EQ..G....GDIVK.GYVKYYNDDEQN.VEYDFYN.LNGEY..G...R..EVLKMYADNKTINSDKL.HLDIYLF.........................
A0A4D6B8D8_9CAUD/152-258 ............................pn--ITVKVYEDNE...--N.I...LSFDIT...TNKKQVTVQELDCKTRK..ILV..SRKNLYE.......FN..N....SPYET.GYIKFIESSGDS.FWYDMMP.APGAI..F...DqsKYLMLYNDNKTVSSSAI.AIEVHL-t........................
A0A4D6B9C0_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
A0A4D6BA83_9CAUD/135-255 ..............................KNIPVNIFIDGV...QQK.YsytDISTVS...TDKKEVTIQELDVKSRY..YLQ..KHFNIYGfgdvkdfGR..SsrfqSGFEE.GNIIFHLNSGER.ISYNLFD.TGHGD..R...E..SMLKKYSDNKTAYSDQL.HIDIYL-v........................
A0A4D6AFU0_9CAUD/135-255 ..............................KNIPVNIFIDGV...QQK.Y...SYTDIStgsTDKKEVTIQELDVKSRY..YLQ..KHFNIYGfgdvkdfGR..SsrfqSGFEE.GNIIFHLNSGER.ISYNLFD.TGHGD..R...E..SMLKKYSDNKTAYSDQL.HIDIYL-v........................
A0A4D6B673_9CAUD/157-257 .............................k-TIYMNVFIDGH...KKDdT...SKYKIT...FEKSPVTFQEVDVRLRKsfMLN..DEIKLY-.......QY..D....SKVLS.GNWEFHGSGEKE.EGADLFK.YPDYR..Y...N..NLIDID--------KKS.HIDV---ylf......................
A0A4D6B5F2_9CAUD/132-236 ..............................IKVPVNVWDKSK...QQP.-...-PMFIT...VNKPKVTAQEVDIKVRK..LLI..KKYDIYN.......NR..E....QKYSK.GTVTLDLNSGKD.IVFDLYY.FGNGD..F...N..SMLKIYSNNERIDSTQF.HVDVSIS.........................
A0A143PA80_9STAP/142-243 .........................apvyp----INVTVKKNaivKNS.F...DIKAFE...TRKDKITLKELDFQIRK..ALI..NNNNLYN.......N-..G....Q--NK.GTVQITTKDNKV.FTFDLSKkLENE-..-...-..-RANIYVDGKNI-----.-------ativadiki................
A0A4D6B6Q1_9CAUD/132-236 ..............................IKVPVNVWDKSK...QQP.-...-PMFIT...VNKPKVTAQEVDIKVRK..LLI..KKYDIYN.......NR..E....QKYSK.GTVTLDLNSGKD.IVFDLYY.FGNGD..F...N..SMLKIYSNNERIDSTQF.HVDVSIS.........................
A0A143P8S7_9STAP/158-249 ..................yisvkttengvt------------...-KD.E...SLNGIN...FNKEEVSLKEVDFKLRK..LLI..DQKGLY-.......--..K....SQYSD.GTIIVHLNNGGR.NTFELHK.-----..-...-..-----------------.-------klqdnrmsdvinstdiqyie.....
SPEC_STRP1/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
A0A097PAT7_BPT12/145-249 ..............................KKIVVKVSIDGI...QSL.-...-SFDIE...TNKKMVTAQELDYKVRK..YLT..DNKQLYT.......NG..P....SKYET.GYIKFIPKNKES.FWFDFFP.EPEFT..Q...S..KYLMIYKDNETLDSNTS.QIEVYL-t........................
SSL7_STAA8/138-227 ...............vnkvyggnldasids------------...---.-...----FS...INKEEVSLKELDFKIRQ..HLV..KNYGLY-.......KG..T....TKYGK.ITINLKDGEKQE.ID-----.-----..-...-..-----------------.-------lgdklqfermgdvlnskdinkievt
A0A4D6AS46_9CAUD/157-257 .............................k-TIYMNVFIDGH...KKDeT...SKYKIT...FEKSPVTFQEVDVRLRKsfMLN..DEIKLY-.......QY..G....SKVLS.GNWEFHGSGENE.EGADLFK.YPDYR..Y...N..NLIDID--------KKS.HID----vylf.....................
A0A4D6AH02_9CAUD/132-236 ..............................IKVPVNVWDKSK...QQP.-...-PMFIT...VNKPKVTAQEVDIKVRK..LLI..KKYDIYN.......NR..E....QKYSK.GTVTLDLNSGKD.IVFDLYY.FGNGD..F...N..SMLKIYSNNERIDSTQF.HVDVSIS.........................
Q2G2X8_STAA8/143-229 ...............kvdakngfsinelff------------...---.-...------...IQKEEVSLKELDFKIRK..LLI..EKYRLY-.......--..K....GTSDK.GRIVINMKDEKK.HEIDLS-.-----..-...-..-----------------.-------eklsfermfdvmdskqikniev...
SPEG_STRP1/126-232 ........................fvgiln--------QDGK...ETY.L...PSEAVR...IKKKQFTLQEFDFKIRK..FLM..EKYNIY-.......DS..E....SRYTS.GSLFLATKDSKH.YEVDLFN.KDDKLlsR...D..SFFKRYKDNKIFNSEEIsHFDIYL-k........................
A0A4D6ADZ5_9CAUD/145-249 ..............................KKIVVKVSIDGI...QSL.-...-SFDIE...TNKKMVTAQELDYKVRK..YLT..DNKQLYT.......NG..P....SKYET.GYIKFIPKNKES.FWFDFFP.EPEFT..Q...S..KYLMIYKDNETLDSNTS.QIEVYL-t........................
A0A4D6AFP8_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
SSL10_STAA8/134-226 ...........lniskekgedafvkgypyy------------...---.-...------...IKKEKITLKELDYKLRK..HLI..EKYGLY-.......--..-....KTISKdGRVKISLKDGSF.YNLD---.-----..L...R..SKLKFKYMGEVIE----.-------skqikdievnl..............
A0A068A244_9CAUD/147-255 ..............................KKVPINLWLDGK...QNT.V...PLETVK...TNKKNVTVQELDLQARR..YLQ..EKYNLYN.......SDvfD....GKVQR.GLIVFHTSTEPS.VNYDLFG.AQGQN..S...N..TLLRIYRDNKTINSENM.HIDIYLY.........................
Q2FZB1_STAA8/143-232 .....................yrlflkysd----------KQ...QTI.I..gGHEFYK...GNKPVLTLKELDFRIRQ..TLI..KNKKLY-.......--..N....GEFNK.GQIKITAD-GNN.YTIDL--.-----..-...-..-----------------.-------skklkltdtnryvknprnae.....
A0A4D6AF66_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
Q99QN1_STRP1/123-230 .............................s-KIVGNLLIDGV...QQK.T...LINPIK...IDKPIFTIQEFDFKIRQ..YLM..QTYKIY-.......DP..N....SPYIK.GQLEIAINGNKH.ESFNLYD.ATSSS..T...R.sDIFKKYKDNKTINMKDFsHFDIYL-w........................
A0A098M2Z8_9BACL/2-83 ...........................sli------------...---.-...------...-------LQSVDMERLE..CFS..KAMQAYN.......DE..A....NKVCK.GLVTVCKKTETD.YEWEITY.YGKSV..FissD..EILKILNQNNDTN----.-------ykekfkelv................
A0EX09_9CAUD/147-255 ..............................KKVPINLWLDGK...QNT.V...PLETVK...TNKKNVTVQELDLQARR..YLQ..EKYNLYN.......SDvfD....GKVQR.GLIVFHTSTEPS.VNYDLFG.AQGQN..S...N..TLLRIYRDNKTINSENM.HIDIYLY.........................
A0A4D6B871_9CAUD/43-143 .............kaiyinifgekelrtlt------------...---.-...AKDKIT...FKNNIVTLQEIDVRLRK..SLMgdSKIKLY-.......EY..D....SLYKK.GFWDIHYKDGGI.RHTNLFT.YPD--..-...-..-----YTDNETIDMSKVsHFDV---hln......................
Q2G2X9_STAA8/138-230 .............nllvkkiddkdgfside------------...---.-...---FFF...IQKEEVSLKELDFKIRK..LLI..KKYKLY-.......--..E....GSADK.GRIVINMKDENK.YEIDLS-.-----..-...-..-----------------.-------dkldfermadvinseqiknievn..
SPEH_STRP1/132-236 ..............................IKVPVNVWDKSK...QQP.-...-PMFIT...VNKPKVTAQEVDIKVRK..LLI..KKYDIYN.......NR..E....QKYSK.GTVTLDLNSGKD.IVFDLYY.FGNGD..F...N..SMLKIYSNNERIDSTQF.HVDVSIS.........................
A0A4D6B8Y4_9CAUD/157-257 .............................k-TIYMNVFIDGH...KKDdT...SKYKIT...FEKSPVTFQEVDVRLRKsfMLN..DEIKLY-.......QY..D....SKVLS.GNWEFHGSGEKE.EGADLFK.YPDYR..Y...N..NLIDID--------KKS.HIDV---ylf......................
A0A4D6AEG5_9CAUD/152-258 ............................pn--ITVKVYEDNE...--N.I...LSFDIT...TNKKQVTVQELDCKTRK..ILV..SRKNLYE.......FN..N....SPYET.GYIKFIESSGDS.FWYDMMP.APGAI..F...DqsKYLMLYNDNKTVSSSAI.AIEVHL-t........................
A0A4D6BB07_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
A0A4D6B7F8_9CAUD/152-258 ............................pn--ITVKVYEDNE...--N.I...LSFDIT...TNKKQVTVQELDCKTRK..ILV..SRKNLYE.......FN..N....SPYET.GYIKFIESSGDS.FWYDMMP.APGAI..F...DqsKYLMLYNDNKTVSSSAI.AIEVHL-t........................
A0A4D6B9P3_9CAUD/1-84 mksryylqkhfniygfgdvkdfgrssrfqs------------...---.-...------...-----------------..---..-------.......--..-....-GFEE.GNIIFHLNSGER.ISYNLFD.TGHGD..R...E..SMLKKYSDNKTAYSDQL.HIDIYL-v........................
A0A4D6BEC5_9CAUD/132-236 ..............................IKVPINVWDKSK...QQP.-...-PMFIT...VNKPKVTAQEVDIKVRK..LLI..KKYDIYN.......NR..E....QKYSK.GTVTLDLNSGKD.IVFDLYY.FGNGD..F...N..SMLKIYSNNERIDSTQF.HVDVSIS.........................
A0A1X9H080_9CAUD/147-255 ..............................KKVPINLWLDGK...QNT.V...PLETVK...TNKKNVTVQELDLQARR..YLQ..EKYNLYN.......SDvfD....GKVQR.GLIVFHTSTEPS.VNYDLFG.AQGQY..S...N..TLLRIYRDNKTINSENM.HIDIYLY.........................
A0A4D6B6I3_9CAUD/132-236 ..............................IKVPINVWDKSK...QQP.-...-PMFIT...VNKPKVTAQEVDIKVRK..LLI..KKYDIYN.......NR..E....QKYSK.GTVTLDLNSGKD.IVFDLYY.FGNGD..F...N..SMLKIYSNNERIDSTQF.HVDVSIS.........................
A0A4D6BCG1_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
A0A4D6AH92_9CAUD/145-249 ..............................KKIVVKVSIDGI...QSL.-...-SFDIE...TNKKMVTAQELDYKVRK..YLT..DNKQLYT.......NG..P....SKYET.GYIKFIPKNKES.FWFDFFP.EPEFT..Q...S..KYLMIYKDNETLDSNTS.QIEVYL-t........................
A0A4D6B8H9_9CAUD/152-258 ............................pn--ITVKVYEDNE...--N.I...LSFDIT...TNKKQVTVQELDCKTRK..ILV..SRKNLYE.......FN..N....SPYET.GYIKFIESSGDS.FWYDMMP.APGAI..F...DqsKYLMLYNDNKTVSSSAI.AIEVHL-t........................
A0A4D6B406_9CAUD/152-258 ............................pn--ITVKVYEDNE...--N.I...LSFDIT...TNKKQVTVQELDCKTRK..ILV..SRKNLYE.......FN..N....SPYET.GYIKFIESSGDS.FWYDMMP.APGAI..F...DqsKYLMLYNDNKTVSSSAI.AIEVHL-t........................
Q99ZZ1_STRP1/101-221 ..............................KNIPVNIFIDGV...QQK.YsytDISTVS...TDKKEVTIQELDVKSRY..YLQ..KHFNIYGfgdvkdfGR..SsrfqSGFEE.GNIIFHLNSGER.ISYNLFD.TGHGD..R...E..SMLKKYSDNKTAYSDQL.HIDIYL-v........................
A0A4D6B6B9_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
Q99XW1_STRP1/125-232 ..............................KNIPVNLWINRK...QIP.V...PYNQIS...TNKTTVTAQEIDLKVRK..FLI..SQHQLY-.......SS..G....SSYKS.GKLVFHTNDNSDkYSLDLFY.VGYRD..K...E..SIFKVYKDNKSFNIDKIgHLDIEI-d........................
A0A4D6BA66_9CAUD/127-234 ..........................hkll----GNLFISGE...SQQ.N...LNNKII...LEKDIVTFQEIDFKIRK..YLM..DNYKIY-.......DA..T....SPYVS.GRIEIGTKDGKH.EQIDLFD.SPNEG..T...R.sDIFAKYKDNRIINMKNFsHFDIYL-e........................
#=GC seq_cons ..................................hNla.cuc...pp.........pIp...hpKc.VThQElDhKlRK..hLh..cpaplY........st..s....otYpp.GpIphthssGcc.hphDLas.hsstt..h...p..shlthYpDNcpls.pph.HhDl.l..........................
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