#=GF ID StcE_b-sandwich
#=GF AC PF20944.1
#=GF DE Metalloprotease StcE, beta-sandwich domain
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE ECOD:520.2.1
#=GF GA 27.00 27.00;
#=GF TC 27.20 28.00;
#=GF NC 26.80 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF RC Paper describing PDB structure 3ujz
#=GF RN [1]
#=GF RM 22483117
#=GF RT Structural insight into the bacterial mucinase StcE essential to
#=GF RT adhesion and immune evasion during enterohemorrhagic E. coli
#=GF RT infection.
#=GF RA Yu AC, Worrall LJ, Strynadka NC;
#=GF RL Structure. 2012;20:707-717.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in Metalloprotease StcE from Escherichia
#=GF CC coli and similar proteins predominantly found in
#=GF CC Gammaproteobacteria. StcE is a virulence factor that contributes
#=GF CC to intimate adherence to host cells. This enzyme is organised
#=GF CC into three distinct globular domains, IG, M and C, that are
#=GF CC packed against each other to show an overall T-shape. This entry
#=GF CC represents a region that is located within the domain IG. This
#=GF CC region folds independently as a mixed, eight-stranded
#=GF CC beta-sandwich and contains an additional beta-strand followed by
#=GF CC a perpendicular arrangement of two alpha-helices in its N
#=GF CC terminus. It is also known as the INS domain. This entry also
#=GF CC covers a disordered region that has been described as D1 [1].
#=GF SQ 111
#=GS A0A2U3MV35_9GAMM/321-390 AC A0A2U3MV35.1
#=GS U3CCD0_9VIBR/42-115 AC U3CCD0.1
#=GS A0A0S2F8F1_LYSAN/230-304 AC A0A0S2F8F1.1
#=GS A0A0S2F8F1_LYSAN/325-397 AC A0A0S2F8F1.1
#=GS F0KH12_ACICP/42-116 AC F0KH12.1
#=GS A0A0T6UP49_9PSED/262-331 AC A0A0T6UP49.1
#=GS A0A1C3EIQ0_9GAMM/181-250 AC A0A1C3EIQ0.1
#=GS A0A2V1GR11_9GAMM/142-216 AC A0A2V1GR11.1
#=GS A0A2V1H9S1_9GAMM/2155-2232 AC A0A2V1H9S1.1
#=GS A0A143G368_9GAMM/226-300 AC A0A143G368.1
#=GS A0A4R7B4T9_9NEIS/276-345 AC A0A4R7B4T9.1
#=GS Q6LPV2_PHOPR/620-690 AC Q6LPV2.1
#=GS A0A1Z5HAA4_9GAMM/579-648 AC A0A1Z5HAA4.1
#=GS STCE_ECO57/177-246 AC O82882.2
#=GS B1KH34_SHEWM/137-212 AC B1KH34.1
#=GS L1LSF2_9PSED/449-516 AC L1LSF2.1
#=GS D0Z201_PHODD/711-781 AC D0Z201.1
#=GS A0A143G368_9GAMM/132-206 AC A0A143G368.1
#=GS A0A4R7B4T9_9NEIS/155-224 AC A0A4R7B4T9.1
#=GS A0A345P9K6_9GAMM/324-393 AC A0A345P9K6.1
#=GS A0A0S2F516_LYSAN/325-397 AC A0A0S2F516.1
#=GS A0A1C3EM92_9GAMM/564-633 AC A0A1C3EM92.1
#=GS S3NB24_9GAMM/134-208 AC S3NB24.1
#=GS S3NB24_9GAMM/228-302 AC S3NB24.1
#=GS A0A1T4UZK1_9GAMM/117-189 AC A0A1T4UZK1.1
#=GS A0A2V1GY26_9GAMM/46-117 AC A0A2V1GY26.1
#=GS A0A0N0E536_9PSED/142-213 AC A0A0N0E536.1
#=GS L1LRV2_9PSED/450-519 AC L1LRV2.1
#=GS A0A0S2F8E8_LYSAN/36-111 AC A0A0S2F8E8.1
#=GS A0A345P9K0_9GAMM/323-392 AC A0A345P9K0.1
#=GS A0A7X8TN46_9VIBR/277-351 AC A0A7X8TN46.1
#=GS A0A0S2F8E8_LYSAN/225-299 AC A0A0S2F8E8.1
#=GS S3MS61_9GAMM/39-113 AC S3MS61.1
#=GS A0A1C3EIQ0_9GAMM/609-679 AC A0A1C3EIQ0.1
#=GS A0A143G368_9GAMM/321-390 AC A0A143G368.1
#=GS A0A2U3MV35_9GAMM/132-206 AC A0A2U3MV35.1
#=GS A0A1C3ELD6_9GAMM/209-278 AC A0A1C3ELD6.1
#=GS A0A345P9K0_9GAMM/134-208 AC A0A345P9K0.1
#=GS A0A506U622_9HYPH/536-604 AC A0A506U622.1
#=GS A0A2V1GR11_9GAMM/335-407 AC A0A2V1GR11.1
#=GS A0A0J1GI46_9GAMM/166-235 AC A0A0J1GI46.1
#=GS A0A506U622_9HYPH/436-504 AC A0A506U622.1
#=GS S3NB24_9GAMM/41-114 AC S3NB24.1
#=GS F0KH12_ACICP/135-209 AC F0KH12.1
#=GS A0A345P9K0_9GAMM/41-115 AC A0A345P9K0.1
#=GS A0A345P9K6_9GAMM/229-303 AC A0A345P9K6.1
#=GS A0A4Q0YYI3_9GAMM/530-599 AC A0A4Q0YYI3.1
#=GS F9R9A3_VIBSN/715-785 AC F9R9A3.1
#=GS A0A2J8GU89_VIBDI/428-496 AC A0A2J8GU89.1
#=GS F9R9A3_VIBSN/288-359 AC F9R9A3.1
#=GS R8AUD1_PLESH/164-233 AC R8AUD1.1
#=GS A0A0S2F516_LYSAN/230-304 AC A0A0S2F516.1
#=GS A0A0S2F8E8_LYSAN/131-205 AC A0A0S2F8E8.1
#=GS A0A2V1GY26_9GAMM/332-404 AC A0A2V1GY26.1
#=GS A0A8H2PM23_9GAMM/589-659 AC A0A8H2PM23.1
#=GS A0A1Z5HAA4_9GAMM/486-555 AC A0A1Z5HAA4.1
#=GS A0KGX4_AERHH/166-235 AC A0KGX4.1
#=GS A0A2U3MV35_9GAMM/226-300 AC A0A2U3MV35.1
#=GS A0A0J1GI46_9GAMM/607-676 AC A0A0J1GI46.1
#=GS A0A097R6E7_HAFAL/2244-2313 AC A0A097R6E7.1
#=GS A0A1T4VVB3_9GAMM/286-357 AC A0A1T4VVB3.1
#=GS A0A448ZT38_9STRA/620-691 AC A0A448ZT38.1
#=GS A0A0J6NIX2_9NEIS/152-221 AC A0A0J6NIX2.1
#=GS A0A345P9K6_9GAMM/41-115 AC A0A345P9K6.1
#=GS STCE_ECO57/601-671 AC O82882.2
#=GS A0A2U3MV35_9GAMM/39-113 AC A0A2U3MV35.1
#=GS A0A4Q0YTS3_9GAMM/182-252 AC A0A4Q0YTS3.1
#=GS A0A2V1GY26_9GAMM/139-214 AC A0A2V1GY26.1
#=GS A0A345P9K0_9GAMM/229-302 AC A0A345P9K0.1
#=GS A7MVS5_VIBC1/480-550 AC A7MVS5.1
#=GS A0A014N664_9GAMM/574-642 AC A0A014N664.1
#=GS D0Z201_PHODD/284-355 AC D0Z201.1
#=GS A0A4R7B4T9_9NEIS/706-776 AC A0A4R7B4T9.1
#=GS A0A142X6Q1_9PLAN/606-676 AC A0A142X6Q1.1
#=GS A0A410ULM7_9GAMM/435-501 AC A0A410ULM7.1
#=GS A0A0S2F8F1_LYSAN/136-210 AC A0A0S2F8F1.1
#=GS A0A0S2F516_LYSAN/41-115 AC A0A0S2F516.1
#=GS S3NB24_9GAMM/323-392 AC S3NB24.1
#=GS R8AUD1_PLESH/588-658 AC R8AUD1.1
#=GS A0A1Z5HD77_9GAMM/467-536 AC A0A1Z5HD77.1
#=GS S3MS61_9GAMM/128-202 AC S3MS61.1
#=GS A0A4P8YQM0_9ENTR/270-339 AC A0A4P8YQM0.1
#=GS A0A1T4VVB3_9GAMM/713-783 AC A0A1T4VVB3.1
#=GS A0A3E1RGE9_9BURK/300-372 AC A0A3E1RGE9.1
#=GS A0A2V1GR11_9GAMM/45-122 AC A0A2V1GR11.1
#=GS S3MS61_9GAMM/317-386 AC S3MS61.1
#=GS A0A014N664_9GAMM/151-220 AC A0A014N664.1
#=GS U3CCD0_9VIBR/130-205 AC U3CCD0.1
#=GS G8Q0P0_PSEO1/565-639 AC G8Q0P0.1
#=GS A0A0N0E536_9PSED/49-123 AC A0A0N0E536.1
#=GS G8Q0P0_PSEO1/470-545 AC G8Q0P0.1
#=GS A0A0S2F8F1_LYSAN/41-116 AC A0A0S2F8F1.1
#=GS A0A1E7F879_9STRA/371-450 AC A0A1E7F879.1
#=GS A0A316F001_9BURK/44-118 AC A0A316F001.1
#=GS B1KH34_SHEWM/48-121 AC B1KH34.1
#=GS A0KGX4_AERHH/590-659 AC A0KGX4.1
#=GS A0A345P9K6_9GAMM/135-208 AC A0A345P9K6.1
#=GS F0KH12_ACICP/229-303 AC F0KH12.1
#=GS G8Q0P0_PSEO1/659-733 AC G8Q0P0.1
#=GS A0A143G368_9GAMM/39-113 AC A0A143G368.1
#=GS A0A0S2F8E8_LYSAN/320-392 AC A0A0S2F8E8.1
#=GS F0KH12_ACICP/324-393 AC F0KH12.1
#=GS A0A2V1GY26_9GAMM/236-311 AC A0A2V1GY26.1
#=GS A0A1C3EM92_9GAMM/996-1066 AC A0A1C3EM92.1
#=GS Q6LPV2_PHOPR/196-265 AC Q6LPV2.1
#=GS S3MS61_9GAMM/222-296 AC S3MS61.1
#=GS A0A8H2PM23_9GAMM/165-234 AC A0A8H2PM23.1
#=GS A0A142X6Q1_9PLAN/182-251 AC A0A142X6Q1.1
#=GS D2U1F4_9GAMM/266-334 AC D2U1F4.1
#=GS A0A2V1GR11_9GAMM/239-314 AC A0A2V1GR11.1
#=GS A0A0S2F516_LYSAN/137-210 AC A0A0S2F516.1
A0A2U3MV35_9GAMM/321-390 .....QPTTRIKVANANWQP.SLNLP..LVAQV..GDKVIFNS....TANYQTNI..TSAN---G...INDTLS.KEESLRYKYTAT--GWTKD-s.....
U3CCD0_9VIBR/42-115 ...da--NIVIQTMDANWNK.EIYLP..AYPSN..GDVVSFVA....NATYTSRL..VGNL-L-G..fGSLEMH.TKDKLDVVFDAHLSAWRL--kn....
A0A0S2F8F1_LYSAN/230-304 ....v-PNTEIKFANGNWTP.NLTLP..ATAGD..RDRISVIS....DATWLATI..GNQNLATT...STLKLF.PGARYDFIFIKENNHWALQS......
A0A0S2F8F1_LYSAN/325-397 ....t-PLVRFNTLDGNWSK.KIFLP..VNAQA..GDEVIVKS....DATFGFEV..TGQSTAF-...GTLPVS.TGETVRFVRDSA-GRWAQD-t.....
F0KH12_ACICP/42-116 ..sdl----EFNLANGNWVK.NLTLP..TSANN..LDKITIRS....SAAYSSYL..DTSNTNIP..lEVLKIN.SGDVYQFIFNSSQNKWIAQ-l.....
A0A0T6UP49_9PSED/262-331 ..the---VVVRLGKSSWAP.NIHFP..SPAQH.kWKSIFVDH....RASNESLL..HVNG----...SVLSVN.KGQQLS--YISDGKVWK---ave...
A0A1C3EIQ0_9GAMM/181-250 .....ADTVKVSTYNGGWRR.SFHLP..SSKEL.dGKKIVFQS....SAGYDSTI..FYGQ----...SSALLR.TNTTKV--FVNYAGVWLS--sa....
A0A2V1GR11_9GAMM/142-216 atiii-----YFVSNHNWTS.SISFP..ASAPK..DALLIVAS....QAYWDSSF..NDTGVLVN..aNRHAIK.YRDLYMYQYDTDEEKWSL--v.....
A0A2V1H9S1_9GAMM/2155-2232 .....YDLVEFSLANANWSReAIVLP..STGVK.nGNKITINS....TATYDSYL..NTSNTNIPv.pNPLVIV.TGTSYTFIYNSTSGLWVK--s.....
A0A143G368_9GAMM/226-300 .....APLTEVIFADGNWIP.NIELP..QTAKD..RDRIVVKS....TAGWEASI..SNSYINTQ...ATLKLN.RGDRYEFMYVADLAKWVLIS......
A0A4R7B4T9_9NEIS/276-345 .....HNAVEIQTYDGAWIK.DFYLP..TNAGL.eGKIVKFTA....DAGYSSLI..HCSG----...KSYELQ.RGVTTL--LRYYRGVWYSQ-d.....
Q6LPV2_PHOPR/620-690 .....HSLVTIGMYNGNWTK.YINVP..AASELnkGRAITINH....RAGYNSHL..QING----...DSVLIY.NGLKTS--YISDGITWNED-e.....
A0A1Z5HAA4_9GAMM/579-648 ..fsn---LTLKVENGRWAR.YIELP..LNYVA.eGREVRVAR....YSTWWTEV..RTGG----...DPVRLQ.KGKEVT--FIFEGGVWKL--kd....
STCE_ECO57/177-246 ....n-ALVEIHTANGRWVR.DIYLP..QGPDL.eGKMVRFVS....SAGYSSTV..FYGD----...RKVTLS.VGNTLL--FKYVNGQWFR--sg....
B1KH34_SHEWM/137-212 ....k-KYVTYTLSNANWYN.TIFLP..SEKGD..ADKILIRS....VATYDTHL..NADNLLHG..qSDLLIK.TGDSFILNWSNKESKWAVQT......
L1LSF2_9PSED/449-516 ....f-KRIEVDLGEGHWAA.DIHLP..ATTDR..LRGVRILS....TAAADSVL..HVNG----...TRVTVK.KGDFLN--YEMD-GTWTR--ve....
D0Z201_PHODD/711-781 ...fd--KVDLSTWNGHWAR.NMSVP..AASEInkGKVFTFNS....SAGYNSHL..AING----...QEMLVP.YGSRLT--FVSDGQTWVKD-a.....
A0A143G368_9GAMM/132-206 ...qm--IQKVQVRNGQWAS.QITLP..NNVAE..GTLINVVS....DAAYDSSI..NTSNLLFA...SSYVLK.NGDSFWFKYSKELAKWVPES......
A0A4R7B4T9_9NEIS/155-224 ....n-STIKIHTYNGGWIS.NFYLP..AGARL.dGKVLLFFS....EAGSKSNI..YYSG----...KTFELQ.LGMTLL--LRNYNGVWYS--md....
A0A345P9K6_9GAMM/324-393 ....t-PVTEVKAADANWQP.TLQLP..LTAQE..GDRVILRS....TATYSVNV..VSGS----...LAERVY.TGENVRFIYNAQ-HQWQRE-t.....
A0A0S2F516_LYSAN/325-397 ....s-PSVRYSASNGNWMP.LLELP..LIGNP..GDKVTVRS....DAAWDFNV..TGQDTTF-...GTIPVR.RGESVRFLRTAS-GAWSLDS......
A0A1C3EM92_9GAMM/564-633 ....a-NTVKVSTYNGAWRR.SFYLP..ESNNL.nGKKIVFQS....SAGYGSTV..NYGK----...LSRPLN.NGSTLV--FVNIHGTWLN--as....
S3NB24_9GAMM/134-208 ...nk--FQRVFLFDGRWAK.KIVLP..SNVID..GTLVQIIS....TATYSSEI..STDNLLFP...SSYRLN.KGSEYWLKYNATLQKWVPE-f.....
S3NB24_9GAMM/228-302 .....APLTEVNFADGNWVS.NFTLP..TTAND..RDRVIIKS....KASWTATI..NNTHTNTS...ATLSLK.TGDQYEFMYVTDKAHWVLM-s.....
A0A1T4UZK1_9GAMM/117-189 ....f-KTVKLITSDGNWIP.ALSLP..SNAFK..NQRLIVER....KATWGTTV..SYKYGSLT...GYTPIK.LQDQLDFVYDGE--KWIIE-p.....
A0A2V1GY26_9GAMM/46-117 .sdiy-----FTTYNGNWTR.DIKLP..KDAEI..GTTIRISS....NAASRSFI..QGVFTGLAk.dVSIPLL.QGQTYL--FAKRTNDW----gi....
A0A0N0E536_9PSED/142-213 ....r--VIRYSLGDGDWTD.NVTLP..GNAGD..GNIVLVRS....DATYSTTI..SPPP-GTG...DPVVMN.RGESYAFVYQYASNRW----ngt...
L1LRV2_9PSED/450-519 ....f-QRVEVDIFDGHWAA.EIFLPipETANR..GKGVRIIH....QATYETTL..HLNG----...TTLQLK.KGDVLN--FVSDGRAW----epy...
A0A0S2F8E8_LYSAN/36-111 ...ya--AIDFYMKNRDWAP.TLTLS..NDAAD..QSTVAIYT....TASMKSNL..IAGNTDYP..lSSLTLN.TGDEVSFVYRASKQQWSM--na....
A0A345P9K0_9GAMM/323-392 .....APLTEVKAADSNWQS.TLQLP..LQAQE..GDRVVLRN....TAPESVNV..VSSQ----...LSEKVN.TGENVRFIYTAQ-HQWQRE-t.....
A0A7X8TN46_9VIBR/277-351 ....s-NFIQMTTYNGNWVK.DIALP..EDPAY.dGKLFQLVH....KAAYNSHV..YSGDDTTG...RYLALSyNGLSQT--FTNIAGKWYL--kp....
A0A0S2F8E8_LYSAN/225-299 ....v-PYTKVSFSNGNWVP.EIILP..TTAGD..RDRISLTS....DATWTANI..SNQNLEAA...GSLKLF.TGARYDFIFIKEKNRWVLQS......
S3MS61_9GAMM/39-113 ...he--NLTFQLRDGDWVP.NLFLP..WYGQD..GDTVIIKS....SAAYASQI..SNLKTDLP...FPLSIK.NNQSYQFKFNAKTRLWHLQ-f.....
A0A1C3EIQ0_9GAMM/609-679 ..ydg---VSVHFWDGKWTR.HIHIP..AASAEnkEKVVLVQH....SAGYTSIL..HING----...GTVELN.KGFSKI--YQSDGKTWA---elt...
A0A143G368_9GAMM/321-390 .....QPTIRVKIGNANWQA.QLALP..SKANI..GDKVIFNS....LADWSTTI..TAEN---G...LKQTIA.AGENQR--YKFSDTGWVRDS......
A0A2U3MV35_9GAMM/132-206 ...qy--IQKVQLKNGQWAK.QISLP..AQAKD..GSLIQVVS....SASNESSI..NTDNLLFS...SSFILK.NGDEFWFKYNEKLEKWVSE-y.....
A0A1C3ELD6_9GAMM/209-278 ...yd--QVTLKTADGSYTG.NISLP..ESVPQ..GKRVVLDV....SSTYAVDV..HATF---R...PTRTVH.TNELVS--WVYMGTSWFEE-g.....
A0A345P9K0_9GAMM/134-208 ..dvl---STYKLADANWVP.LVTLP..ASAAD..GQFVSVQS....SATWASKI..NPQNVLFP...SSFTVK.TGDRYYFRYVTALSQWVPE-l.....
A0A506U622_9HYPH/536-604 .....HQWIEADTADGNWVG.AIVLP..AGVEE..QSRFKLVV....NSTWAVDL..QFGG----...KTQNVK.HGETAE--LAYIDGQWQLQS......
A0A2V1GR11_9GAMM/335-407 ....t-PNMRVSAYNDNWRP.VVRLS..RHATN..GDRITIAS....DANLEFKV..TASDSPLL...GEVFVN.RGDEIQ--FLRTDNRWVRA-t.....
A0A0J1GI46_9GAMM/166-235 .....HDTIQVETADGSWAQ.NFILP..EGEAF.hGKRVTFTS....YAGYNSFI..TYST----...GTDTLS.AGNEFT--YKNQKGKWFAQS......
A0A506U622_9HYPH/436-504 .....HPKISVTTYDGGWLN.TLILP..DHVAE..GSKFLLNV....GSTLAVNL..QFNG----...QTENIT.TGNTAE--LVYSDNRWMVQ-r.....
S3NB24_9GAMM/41-114 ..tdl----KFILADGNWVK.NIYLP..NGAKN..LDTVTIQS....NALYKSYL..DTSNTNLP..iEALEIH.RGDTFQFVYNSNLKKW----eif...
F0KH12_ACICP/135-209 ....a-SMQKVLIQNDKWAQ.TIALP..SDVRD..GTTVQVVS....TASASSDI..DKTNLLFP...SSFTLK.NGSEYWFKYYSALGKWVPE-y.....
A0A345P9K0_9GAMM/41-115 ...dd--LI-FQLGDGNWVP.NITLP..LTAKD..GAKLAITS....SASYESQI..DTTRSDLP..vAQIKVK.AGSTVNFTFSQSLGKWQVES......
A0A345P9K6_9GAMM/229-303 ....s-PINEVTLTDTDLMA.AISLP..ASAND..RDQVIVKS....ATDRVVHI..NNAHTNTL...ATLNVK.RGDQYTFRYIADKAYWIVQS......
A0A4Q0YYI3_9GAMM/530-599 ....a-QTVKVATRNGSWRS.AFYLP..TSEAL.dGKKIVFQS....SAGYGSTV..YYGN----...SSTRLT.NGTTLV--LVNYKGAWLQ--as....
F9R9A3_VIBSN/715-785 ....f-DKVELSTWNGHWAR.DMSVP..EANESnkGKIFTFNS....DAGYHSNL..TING----...ESMVVP.YGSRLV--FVSDGQTWVKD-a.....
A0A2J8GU89_VIBDI/428-496 ....y-DVINVTTYDGVWRS.EFTLP..STDVD.tGKVINFKA....SATYSSTV..YHDG----...SGDVIT.TGNSVSYRFN--G-------flwekt
F9R9A3_VIBSN/288-359 .....HDVVKLNTWNGHWIR.DIALE..QNNPElnGKTFIFQS....SAGYNSNV..SYYQ---D...RTRTIV.NGTTTV--FKNVNGAWVLE-d.....
R8AUD1_PLESH/164-233 ....s-ALVEIQTADGRWVR.DIYLP..QGAEL.eGKMVRISS....RAGYNSNL..YYGE----...RKVTVS.NGQTIA--FKYANGQWFRE-g.....
A0A0S2F516_LYSAN/230-304 ....v-PYTQVQFGDGATIP.DIRLP..ASAGD..RDRVSISS....EAVSASTI..SNLNVDTT...ATLKLF.AGSRYDFIYIKERALWALQS......
A0A0S2F8E8_LYSAN/131-205 ....g-KLLRFDLANGDWAQ.TITLP..ASAPD..GSVIAIAS....TATWTSRI..DAQNVMFA...GTFNIR.TGDQYAFVFRANLQRWVS--vk....
A0A2V1GY26_9GAMM/332-404 ....t-PNTHVTVHNRNWNS.EVRLS..RHATN..GDRVTITS....GADLEFEV..TSSDSPLL...GAVSVS.SGEEIQ--FLRAENRWVRA-t.....
A0A8H2PM23_9GAMM/589-659 ....y-DLVNIAMYNGNWSK.YITVP..AASDAnkGRVISINH....NAGYNSHL..LING----...ESIVIY.NGLKTS--YRSNGTTWSE--te....
A0A1Z5HAA4_9GAMM/486-555 ...fp--NLTLEVVNGRWAR.YIDLP..RDGIK.eGRKVRVAR....YSTWWTAV..RTGY----...DSVIIN.RGDVAT--FTFKNGSWR---tey...
A0KGX4_AERHH/166-235 .....HALVTIQTADGRWVR.DIHLP..RDASL.eGKMVRLAS....NAGYNSTV..YFSG----...RQVTIS.RGQSQQ--FKFVRGQWIRD-g.....
A0A2U3MV35_9GAMM/226-300 .....APVTEILFANGNWVA.EIVLP..KTAKD..RDRIVFKS....TAAWQAKI..SNENTSTS...STLKLK.NGDRYEFLYVADIAKWVLIS......
A0A0J1GI46_9GAMM/607-676 ....f-DAIRFSLGNGDWAR.DLYLL..DDAAF.eGKVAQFQS....WAGWTAYV..HVNG----...TTRALK.TNEKFA--YQFTNGAWVE--ve....
A0A097R6E7_HAFAL/2244-2313 ..yes---ILYNFRDGSWSN.SVTLP..STAAT..GSAVRIVS....AAIQDTTI..SYSG----...NTLVMN.KNSNTPTSFLFNGSSWVKQ-......
A0A1T4VVB3_9GAMM/286-357 ....n-DVVELKTWNGHWLR.DIVLE..QNNPAldGKTFAFTS....SAGYNSVV..SYYQ---E...RKKTIV.NGTTTV--FKNVKGTWVLE-d.....
A0A448ZT38_9STRA/620-691 ..ykd---VELHTYDGSWIR.ELYLP..KANGIlsGSSLTIKC....NSTWGVKV..LYPG---N...WQKDVA.TKTTLA--LIVKEGKWIVK-k.....
A0A0J6NIX2_9NEIS/152-221 ...nv--MVNIQTADGSWVK.TVYLP..ADPAF.eGKMIRFQS....QAGYGSTV..RYSS----...RSVDVS.RGDTLL--FKYVNGQWFRQ-g.....
A0A345P9K6_9GAMM/41-115 ...dd--LI-FQLSNGNWVP.NLTLP..LTAKD..GAKLSITS....SAGYDSQL..DATRSDVP..vAQITVK.AGNTFNFIFSLASGKWQLQS......
STCE_ECO57/601-671 ....y-AVVKVHMWNGNWTR.NIYIP..TASADnrGSILTINH....EAGYNSYL..FING----...DEKVVS.QGYKKS--FVSDGQFWKE--rd....
A0A2U3MV35_9GAMM/39-113 ..tel----DFNLFNGNWVE.NLTLP..KTASD..KAVVKITS....DAGYASYL..DTSNTDIP..lESLKIT.KGSSYTFIFDLAQKKWNLD-v.....
A0A4Q0YTS3_9GAMM/182-252 ...yd--GVKVHFYNGNWTD.NIHIP..AASSDniGKVLTVGH....SAGWGTTL..HING----...GTVSVK.SGFAKN--YRSDGSQWVE--ge....
A0A2V1GY26_9GAMM/139-214 ...at--IILYSIANNNWAP.SISFP..ASAPN..NALLIVKS....HASRNSSF..SDTGVLAY..aNHYAVK.NRDSYIYQYNTEDSKWFP--il....
A0A345P9K0_9GAMM/229-302 .....APINEVTVTDQD-SG.EINLP..VSAND..RDQVIIKS....ATDQNVQI..NNAHTNTS...ATLNVK.RGDQYEFRYIADKNYWIVQS......
A7MVS5_VIBC1/480-550 ....f-DITKVETGDGRWIR.DIYLP..SAENVavGKAVNIAR....YSGYGVTA..HVNG----...QLVNLN.RGDSKF--YISDGKAWLE--tt....
A0A014N664_9GAMM/574-642 .....HQVVKVYMADGNWAQ.NIPVP..PASALnrHKIITVEH....HASWNSQL..HLNG----...KTILVT.KGFSQS--YRSEEAGWT---a.....
D0Z201_PHODD/284-355 .....HDTVVMRTWNGHWNR.MFDLE..QDNPKldGKTFVFIS....SAGYNSHV..NYYK---D...RSRTIV.NGTTTV--FKNVNGAWILQ-d.....
A0A4R7B4T9_9NEIS/706-776 ....f-DKVKINFYDGFYNS.QIYIP..TASVEnkGKIIHVKH....EASNASNM..HING----...LTVPLR.NGDEMF--FLSADGEWK---nid...
A0A142X6Q1_9PLAN/606-676 ....y-DVVRVAMGDGNWTK.NIELP..AAAPAnrGRRVTIDH....AASYDSVL..FLNG----...GQLQVS.RGFQKT--YLSDGKRWKEE-r.....
A0A410ULM7_9GAMM/435-501 ...yr---VSVRTSDGNWTR.EIILP..AHSRE..KAKFNLIV....QSQYPVQL..TYGN----...KSHEIA.RGTTVN--LVFNNGRWTE--q.....
A0A0S2F8F1_LYSAN/136-210 ....g-KYTRFDIADGDWAQ.AITLP..ASAPD..NSVLAVGS....TASWGSKI..SSQNLQFA...STFNLR.AGDQYVFVYQTKFQRWFS--vk....
A0A0S2F516_LYSAN/41-115 ....y-PAIDFYLRNGDWAP.NLTLS..NAAGD..QYKVAIHS....SAAYDSQL..ATTNTDYP..iGSMRIR.SGDNISFIYQASRRQWS---fv....
S3NB24_9GAMM/323-392 .....QPILKVNISDANWKP.NIKLP..IKAQI..GDKVILSS....TAKTHSFI..TAEN---G...LSATVQ.TGENRRFIYTSQ--GWNID-s.....
R8AUD1_PLESH/588-658 ....y-ELVKIGMWNGHWAR.NIYMP..AASSEnrGRSISIDH....RAGYNSHL..FING----...SEILVS.NGYKKT--FTSDGQRWQE--ra....
A0A1Z5HD77_9GAMM/467-536 ..fsn---LTLKVENGRWAR.YIELP..LNYVA.eGREVRVAR....YSTWWTEV..RTGG----...DPVRLQ.KGKEVT--FIFEGGVWKL--kd....
S3MS61_9GAMM/128-202 ....a-ALQTVVINDDNWVS.SLRLP..QGARD..GSMLKISS....ESQKTTRI..NSEGVLFA...STLSLK.KDEAHWYRYYQALNKWVAES......
A0A4P8YQM0_9ENTR/270-339 ....v-DLVAIRSQDGHWAP.NIYFP..EPNKL.kWKSIFVDH....RAGYSSSI..HVNG----...SIMKVN.KGQHIM--YMSDGSSWKV--in....
A0A1T4VVB3_9GAMM/713-783 ...fd--KVDLSTWNGHWAR.DISVP..VASASnkGKIFTFKS....DAGYHSYL..DING----...EQITVP.NGSRLL--YVSDGQTWVKD-g.....
A0A3E1RGE9_9BURK/300-372 dlvwd-------SSDGNYST.HVILP..TTSTD..GVRVHMQN....HASYYYQV..DTNNTNLD...ASLPIG.RLATADFVFSAAQGKWIYE-g.....
A0A2V1GR11_9GAMM/45-122 ..yse---INFSTYDRNWIN.DIKLP..PNAQI..GTTIRISS....NTTAPSAIrgVFTGISGLtkdVSIPLL.EGQSYL--FTKRSGDWD---ihg...
S3MS61_9GAMM/317-386 .....YPVTKVIVNPSNWQA.ALQLP..NKAQI..DDKVILES....SALQTIQV..SSKN---G...LKASLR.NGETQRYIYTAK--GWVADS......
A0A014N664_9GAMM/151-220 .....HSVVEIRTADGRWTR.NIFLP..ENGVS.eGKLIRVIS....NAGYTSTI..TFSG----...RTTIIS.RGDTFHF--KYISGQWILD-t.....
U3CCD0_9VIBR/130-205 ....k-RYVSYYVADANWNS.LLHLP..SQKGQ..ASKILVRS....QALYDTYV..DNSMLGNM..gANLKIK.QGEYYVFTWNDAKAKWDV--id....
G8Q0P0_PSEO1/565-639 ....e-KLVRYRTEDYNWTE.RISLP..TSAPA..YRYVEIASyitaTEGWHSQI..HRRS---G..dRVYRCQ.RGDQFLFMFN--LGSWQA--ik....
A0A0N0E536_9PSED/49-123 ..fpm----TFRTGDGDWAS.DLSLP..DLAPA..AAQLTVST....GASYPSVL..SLRNTDIG..vQSISMN.RGDSLAFLYDSASQRWKVQT......
G8Q0P0_PSEO1/470-545 ...ye--AIALETYNGNWVP.LMLLP..SSARN..TSTVLILC....KAQSNATL..QSSRWDFP..vADMTLA.QGDVLLFEYDSSLAKWILQ-f.....
A0A0S2F8F1_LYSAN/41-116 ..yas---IDFYISKDDWAS.TLTLS..NSAAD..QSTVTIHS....STGKTSNL..IAGNTDYP..lTSMTIY.KDDHVTFVYQAAKQRWVV--ta....
A0A1E7F879_9STRA/371-450 ...qn--QVEIKTSNGSWVR.DIYLP..TGLSVpsNSKVQITC....NSGYNVNL..YYPNTQTGigyRKKTVT.NGQTLVAILVDNGFTWIT--kd....
A0A316F001_9BURK/44-118 ....a-PRQVLNIGDADWAP.VLRLP..RRAPA..HARLFLSS....TAARDSRI..DGANVEGY...ATLGLN.RGDAYEFLFIAERAKWRL--fk....
B1KH34_SHEWM/48-121 ....d-EVVTVYASDANWKR.EIFLP..IKPKN..NTKINVSS....DAAYHFDV..NGEIVGF-...NEITVS.KGDRYQFVYKNNLRSWLL--tt....
A0KGX4_AERHH/590-659 .....YDLVKVAMWDGNWTR.NIQLP..AASAVnrGRIVSIDH....NAGYNSTL..FING----...QQITVS.RGFKKS--YRSDGSRWN---eg....
A0A345P9K6_9GAMM/135-208 ..fls----TYKLADANWVP.EVTLP..ASAVD..GQFVSVQS....TATWASKI..NTQNVLFP...SSFTVK.TGDRYYFRYVAALSQWVPES......
F0KH12_ACICP/229-303 .....SPLTEVSFGDGNWVS.NFTLP..TTASD..RDRIIIKS....TATWSAKI..NNTNINSQ...ATLTLK.TGDQYEFMYVSDKGYWQLI-s.....
G8Q0P0_PSEO1/659-733 ..tek---TEVHFSDGDWIE.QITLP..VTAWQ..NDEVTLTS....NAGYTSTV..MGTNLESG...TPVQFN.RGETLQFRYIASTGKWRR--il....
A0A143G368_9GAMM/39-113 ..sdl----QFNLSNGNWVQ.NLNLP..TSASD..KDVITISS....EAGYPSYL..ETSNTDLP..iESLSIR.QGQSLSFIFDKNSNKWLV--ka....
A0A0S2F8E8_LYSAN/320-392 ....s-PAARYTAADGNWIA.SLALP..VNASP..GDRLVVKS....DASWDFNV..SGQSTTF-...GTVPVR.KGETLRFVRNAA-GAWALD-t.....
F0KH12_ACICP/324-393 ....q-PTLKVKLSTSNWQP.TLQLP..AKAQV..GDKVVIVS....NASADTYI..NAAN---G...LSTAIK.NGENRRFIYTAQ--GWTVDS......
A0A2V1GY26_9GAMM/236-311 ....s-PLMVLSLSDSSWTR.RITLP..AQAFD..RDRIRITS....TGALQSEI..NHQGVEDN..vGSLLVN.SGDVYEFMYVESDQEWKLI-k.....
A0A1C3EM92_9GAMM/996-1066 ..ydg---VSVHFSNGYWAG.NIHIP..SASAEnnGKMLKVGH....SAGWNSRL..HIND----...SVITLS.WGTVKN--YQSDGETWVE--ms....
Q6LPV2_PHOPR/196-265 ....n-NLVEINTADGVWTK.NVYLP..TSTSM.aDKVVRVTS....RAGYSSNI..HYSG----...RSTTIT.RGNTQV--FKHLNGQWIRE-g.....
S3MS61_9GAMM/222-296 ....a-ALTQVNFSDANWLE.NLTLP..VNAQD..RDRIIVTS....TAAWPAKI..NNTNINSN...ASLTLL.KNDRYEFVFIADQEKWIIDS......
A0A8H2PM23_9GAMM/165-234 ....n-NLVDIHTADGVWTR.NIYLP..NSTSM.tNKVVRVNS....TAGYSSQV..FYSG----...RSVPLH.DNQKLV--FKQINGQWFLD-g.....
A0A142X6Q1_9PLAN/182-251 .....SPVVEIQTADGQWVR.DIYLP..AGTGF.eKKLLRVVS....HAGYTSTI..HYSG----...RSAVIA.RGQTLQ--FKFVGGQWIHES......
D2U1F4_9GAMM/266-334 ....n-ALIAIKTYDGSWAP.KIYFP..DANKY.kFKSIYIKS....NASYPSTL..YFDN----...KQLRIN.KSEKLM--FVSDGNEWIIQ-......
A0A2V1GR11_9GAMM/239-314 ....s-PLTVLSLGDGSWTG.RTTLP..TQAFD..RDRVRITS....TATWQSQI..SHQGVEDN..iGSLSVN.RGDVYEFMYAGNEQEWKL--lk....
A0A0S2F516_LYSAN/137-210 ...sf---LRFSLANGDWAQ.TVTLP..AVAPD..GSLLVVSS....TASSTSRI..SPQNIMYS...STFNVR.AGDQYAFIYRASLKRWISI-k.....
#=GC seq_cons .......hlclphtsGsWsp.slpLP..ssusp..GctlplpS....sAuasSpl..phss.......sohslp.pGsphp..atsstspWhh........
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