#=GF ID Swm2
#=GF AC PF17083.9
#=GF DE Nucleolar protein Swm2
#=GF AU Llagostera M;0000-0001-8177-8321
#=GF SE Manual
#=GF GA 25.00 25.00;
#=GF TC 25.00 51.90;
#=GF NC 24.90 20.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 10688190
#=GF RT A comprehensive analysis of protein-protein interactions in
#=GF RT Saccharomyces cerevisiae.
#=GF RA Uetz P, Giot L, Cagney G, Mansfield TA, Judson RS, Knight JR,
#=GF RA Lockshon D, Narayan V, Srinivasan M, Pochart P, Qureshi-Emili A,
#=GF RA Li Y, Godwin B, Conover D, Kalbfleisch T, Vijayadamodar G, Yang
#=GF RA M, Johnston M, Fields S, Rothberg JM;
#=GF RL Nature. 2000;403:623-627.
#=GF RN [2]
#=GF RM 18719252
#=GF RT High-quality binary protein interaction map of the yeast
#=GF RT interactome network.
#=GF RA Yu H, Braun P, Yildirim MA, Lemmens I, Venkatesan K, Sahalie J,
#=GF RA Hirozane-Kishikawa T, Gebreab F, Li N, Simonis N, Hao T, Rual
#=GF RA JF, Dricot A, Vazquez A, Murray RR, Simon C, Tardivo L, Tam S,
#=GF RA Svrzikapa N, Fan C, de Smet AS, Motyl A, Hudson ME, Park J, Xin
#=GF RA X, Cusick ME, Moore T, Boone C, Snyder M, Roth FP, Barabasi AL,
#=GF RA Tavernier J, Hill DE, Vidal M;
#=GF RL Science. 2008;322:104-110.
#=GF RN [3]
#=GF RM 20360394
#=GF RT Mutational analyses of trimethylguanosine synthase (Tgs1) and
#=GF RT Mud2: proteins implicated in pre-mRNA splicing.
#=GF RA Chang J, Schwer B, Shuman S;
#=GF RL RNA. 2010;16:1018-1031.
#=GF DR INTERPRO; IPR031391;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC The nucleolar protein SWM2 (Synthetic With MUD-2-delta protein2)
#=GF CC constitutes a yeast protein family. SWM2 is a nonessential gene
#=GF CC whose function is unknown, but it encodes a protein that binds
#=GF CC Tgs1, an enzyme responsible for 2,2,7-trimethylguanosine (TMG)
#=GF CC capping [1,2] of small nuclear (sn) RNAs implicated in pre-mRNA
#=GF CC splicing [3].
#=GF SQ 21
#=GS H2AZF8_KAZAF/11-132 AC H2AZF8.1
#=GS A0A7H9B052_ZYGMR/14-146 AC A0A7H9B052.1
#=GS A0A1G4MFJ5_LACFM/13-123 AC A0A1G4MFJ5.1
#=GS G8C1N5_TETPH/17-147 AC G8C1N5.1
#=GS A0A7H9I177_9SACH/67-199 AC A0A7H9I177.1
#=GS G0VIG7_NAUCC/16-147 AC G0VIG7.1
#=GS J8PWZ7_SACAR/14-143 AC J8PWZ7.1
#=GS G8ZQ05_TORDC/15-146 AC G8ZQ05.1
#=GS A0A4C2EBE8_9SACH/7-121 AC A0A4C2EBE8.1
#=GS J7RPG8_KAZNA/21-141 AC J7RPG8.1
#=GS SWM2_LACTC/13-124 AC C5E3I1.1
#=GS SWM2_VANPO/14-144 AC A7TRI3.1
#=GS G0W9H0_NAUDC/18-145 AC G0W9H0.1
#=GS A0A0C7N2L8_9SACH/13-121 AC A0A0C7N2L8.1
#=GS A0A1S7HZZ8_9SACH/8-121 AC A0A1S7HZZ8.1
#=GS A0A1G4K5L6_9SACH/13-121 AC A0A1G4K5L6.1
#=GS A0A1G4JLT1_9SACH/13-124 AC A0A1G4JLT1.1
#=GS I2H3N3_TETBL/24-177 AC I2H3N3.1
#=GS A0A1S7HQZ2_9SACH/8-121 AC A0A1S7HQZ2.1
#=GS J6ECB4_SACK1/14-162 AC J6ECB4.1
#=GS SWM2_YEAST/14-144 AC P40342.1
H2AZF8_KAZAF/11-132 ..IDHFDDLTKIPPEFTATIIPYLRNIE..ASKNQTKEILRKCKSIFDRWES.SDA...................DI.STLL.LTRCLEIWSCIKGEEYFL...-ENEPLTN.....LIIEEVDAGNY--.....TQKFRTKYSDSGSA.........-----LDNLILEEVEVRDFL
A0A7H9B052_ZYGMR/14-146 ..LNSFTNTQVIPKSYSELLLPFYKSIA..LNEKLRGIALSKCRQTFSQWEN.YDA...................NLtDPEA.VQRCLDLWLTIKGQDYNL..tRSLPSSSN.....IIIEDIEVTNYVG....pQEFERLEFHPVTHE.........LLSNPLSNLIVEEVEATQFV
A0A1G4MFJ5_LACFM/13-123 ..LKDFTNLDLIPASLTPALGYFYTAIA..RDEDLRQQASNKCSQVLEDLTS.HSA...................--.--EV.VKRCSQFYEVLSAH----...-VPPPFPN.....LIIGQVDVNGT--.....TDMPVLSPHQ----.........----HLTNLIIEDIDVTQYI
G8C1N5_TETPH/17-147 ..LNNFTENPELLNEFSDSLSVIYESIA..KNRIFSSLASSMCQQVFNRWEN.RNK...................TV.DKNV.LRCCLDMWLIIKGTDYDI..pKFEEIVSN.....LIIEEADVSQYFS.....ENDERLEFDEITNE.........VLVDPLSNLILEEVEVTEFV
A0A7H9I177_9SACH/67-199 ..LNIITDLDRLPKEYNAFLQPLFDKIK..KDDELSIAALEKCELTFASWDN.QEP...................DG.PNELaIRRCMDLWLTIKGEDYPL..rKPLSNPAN.....LVVEEIEVCDFVD....kNDLKRTEFDPVTGE.........PIDNNLGNLIIEEVEATDYV
G0VIG7_NAUCC/16-147 ..LNGFVDLEKVPKEFTSQLIPYFEAIS..QDKDLKRVAKKICRTIFEQWEE.KQD...................AV.DAEV.IKRCQDFWIVLGHTPYLQ..vPDYEPY-N.....LVIQNVDAAEFISe..hgTTKEKLEFDE-RDN.........LITNPLDNLILEEVEVTDFV
J8PWZ7_SACAR/14-143 ..LDGLTDLNKIPKEYSLLLEPYFQSIA..KHTHLKSKGLKLCRFNFRKWDA.QDG...................TV.DPEA.IRRCLDLWYVLKGKEYKK..lKNPPSVYN.....IIKDEVDVSHMEN.....LKVTRLEFDE-FGK.........PITNPLHNLILEEVEVNDFI
G8ZQ05_TORDC/15-146 .v-KLFTTLSAIPETYSPLLLPLYCEIK..KNDQLSFEALKNCKEIFAKWNN.GED...................DV.EEEV.VKRCMDMWLTINGEDYIL..kKPLSSIPN.....ITRQEAETNDYVG....eSELQRIEFDPITNE.........PIKNPLGNLIIEEVEATEYV
A0A4C2EBE8_9SACH/7-121 ig--DLQDLETLPSSQSSTLESQYQLIA..ADEKLSKKAIDRCEQVFQLWSS.NRG...................-V.RIET.IKRFKQLWSIIKDRDYPL...-VGFPYPN.....VTAQQVDVDQYMK.....-----HQR------.........--EKSMKNLTVEEVEITDYV
J7RPG8_KAZNA/21-141 ..LDIVLDLEQLPEDQTDTMLSYLSVAN..LNEEQKSQYLIKCEEVLGQSEQ.VRD...................-V.SQGL.YERCTKILNLLTGKPYGA...-EASDLSN.....LVIEETDIRDVTV.....-------EDTVSSR.........LGRTSLRNLIVEEVEVTDFV
SWM2_LACTC/13-124 ..LDSFTDIAVIPVRLTPVLSRYYDAIA..KDPELSKLALEKCNYVLENLSA.HSP...................--.--EI.VTRCSRLYEALTAA----...KERDAAGN.....LIVEHINLESV--.....SDMPFLSRDQ----.........----HMANLIIEEIDVADYI
SWM2_VANPO/14-144 ..LRNFRDSPVLLKEYGPYLSYHYKVVA..NDGELSLNAVRICEELFNDWQN.GDH...................TI.AKEV.VQCALDMWFVMKGEEYDL...KGFEYIPN.....LIIQEIDVAKGKN....tGEIHRIEFHPSTNE.........PIDEPLNNLILEEVEVHDFI
G0W9H0_NAUDC/18-145 ..LNNFDDLNLISENYTEFLLPYFEAIS..KDNKLRRLAKKKCKNYFERWVS.TND...................--.-KEI.STRYQEFWFILNGTFYEL...-EGNLFHN.....LIINEVDIKEYENv...lNNQAKKEFEPDTGK.........PLPNPLNNLILEEVEVTDYV
A0A0C7N2L8_9SACH/13-121 ..LQNFTDINIIPVKLSAALPGYYHAIA..SDPELSAIASKKCDAVLQELSH.HNS...................--.--EI.VARCSSLRQSIEAS----...---KNPTN.....VIQEHVDLQDL--.....SDMPFLSSQQ----.........----HMANLIIEEIDLKDYI
A0A1S7HZZ8_9SACH/8-121 ..IDKLTDLDSMSCLGESELYRLYELIA..ADKETALKFKTKCEAIFNLWQH.SK-...................-V.SPEV.VNRFRDLWLLIEGSDYPL...EGFERY-N.....LVVEEIDVSEY--.....-----LESRK----.........--RKSLRNLILEEVEVTDYV
A0A1G4K5L6_9SACH/13-121 ..LDAFTDISVIPVALSSALLTYYEAIA..NDPELARTATLKCKTVLKEYSN.YNP...................--.--EV.VTRCSQFQTILDAP----...---KTPQN.....LILEHTNLQTV--.....TDTPFISSAQ----.........----HMANLIVEEIDLADYI
A0A1G4JLT1_9SACH/13-124 ..VDNFTQLELIPASFTPILDPYYTEIA..KNQELKDRASEICNAVLKDYQN.YNP...................--.--EI.VKRCSRFHGVLAQS----...QQNPRLDN.....LIIEDIDVTAS--.....------KFSQFTDD.........--REHMGNLIVEEIDVEQFV
I2H3N3_TETBL/24-177 ..INSFTNLKIIPLIDRNVLFQYYYGISrsNDKNLILKAQNICEEIFSLRKQ.DKY...................LI.EDAI.LDRCLDMWYILNGNYYQLaneTKNNKYSNqanswQISLESEVKNEQNnkgidNVFEKNERDDSNKDralasepklHLKASISNLIVEEVDVCDYI
A0A1S7HQZ2_9SACH/8-121 .i-EKLTDLDSMSCLGESELYRLYELIA..ADKEASLKVKTKCEAIFNLWQH.SQA...................--.NPEV.VSRCRDLWLLIEGKDYPL...EGFERC-N.....LVVEEIDVSEY--.....-----LESRK----.........--RKSLRNLILEEVEVTDYV
J6ECB4_SACK1/14-162 ..LDGLTDLNRIPKEYSPLLEPYFQNIA..NNTHLKFKALKICRFNFHKWNT.LDSknsksisphckaendkfskAV.DPEV.IRRCLNLWYVLRGKEYKK..lKNPPSANN.....IIKDEVDVSNIKG.....LNLVRLEFDE-FGK.........SIRNPLNNLILEEVEVNDFL
SWM2_YEAST/14-144 ..LDGLTDLNRIPKEYSAVLEPYFQNIA..RNAHLKSRALKICRSNFHKWNEeGAK...................TV.NPEI.IRRCLNLWYVLKGKEYKK..lKDPPPADN.....IIKDEIDVSYVKN.....LNVVRLEFDE-FGK.........LISNPLENLILEEVEVNDFI
#=GC seq_cons ..LcsFTDLshIPpphoshL.saYpsIA..pcpcLptpAhcpCcplFppWps.pss....................l.p.El.lpRChchWhllcGp.Y.h...pt.pshsN.....LIl-ElDVsph.......tph.hlEhcp..tp...........ppsLsNLIlEEVEVsDal
//
