#=GF ID T2SSG
#=GF AC PF08334.15
#=GF DE Type II secretion system (T2SS), protein G
#=GF PI GSPII_G; T2SG;
#=GF AU Fenech M;0000-0001-7933-4617
#=GF AU Desvaux M;0000-0003-2986-6417
#=GF SE Pfam-B_1144 (release 18.0)
#=GF GA 21.00 21.00;
#=GF TC 21.00 21.00;
#=GF NC 20.90 20.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF CL CL0327
#=GF RN [1]
#=GF RM 15491357
#=GF RT Structure and assembly of the pseudopilin PulG.
#=GF RA Kohler R, Schafer K, Muller S, Vignon G, Diederichs K,
#=GF RA Philippsen A, Ringler P, Pugsley AP, Engel A, Welte W;
#=GF RL Mol Microbiol 2004;54:647-664.
#=GF RN [2]
#=GF RM 1588814
#=GF RT Protein secretion in Pseudomonas aeruginosa: characterization of
#=GF RT seven xcp genes and processing of secretory apparatus components
#=GF RT by prepilin peptidase.
#=GF RA Bally M, Filloux A, Akrim M, Ball G, Lazdunski A, Tommassen J;
#=GF RL Mol Microbiol 1992;6:1121-1131.
#=GF RN [3]
#=GF RM 2129543
#=GF RT Five additional genes in the pulC-O operon of the gram-negative
#=GF RT bacterium Klebsiella oxytoca UNF5023 which are required for
#=GF RT pullulanase secretion.
#=GF RA Reyss I, Pugsley AP;
#=GF RL Mol Gen Genet 1990;222:176-184.
#=GF RN [4]
#=GF RM 15223057
#=GF RT The general secretory pathway: a general misnomer?.
#=GF RA Desvaux M, Parham NJ, Scott-Tucker A, Henderson IR;
#=GF RL Trends Microbiol. 2004;12:306-309.
#=GF RN [5]
#=GF RM 14600218
#=GF RT Type II protein secretion and its relationship to bacterial type
#=GF RT IV pili and archaeal flagella.
#=GF RA Peabody CR, Chung YJ, Yen MR, Vidal-Ingigliardi D, Pugsley AP,
#=GF RA Saier MH Jr;
#=GF RL Microbiology. 2003;149:3051-3072.
#=GF RN [6]
#=GF RM 19299134
#=GF RT Secretion and subcellular localizations of bacterial proteins: a
#=GF RT semantic awareness issue.
#=GF RA Desvaux M, Hebraud M, Talon R, Henderson IR;
#=GF RL Trends Microbiol. 2009;17:139-145.
#=GF DR INTERPRO; IPR013545;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC The Type II secretion system, also called Secretion-dependent
#=GF CC pathway (SDP), is responsible for the transport of proteins
#=GF CC across the outer membrane first exported to the periplasm by the
#=GF CC Sec or Tat translocon in Gram-negative (diderm) bacteria [1,2].
#=GF CC The T2SG family includes proteins such as EpsG (P45773) in
#=GF CC Vibrio cholera, XcpT also called PddA (Q00514) in Pseudomonas
#=GF CC aeruginosa or PulG (P15746)in Klebsiella pneumoniae. The PulG is
#=GF CC thought to be anchored in the inner membrane with its C-terminus
#=GF CC directed towards the periplasme [3]. Together with other members
#=GF CC of the Type II secretion machinery, it is thought to assemble
#=GF CC into a pilus-like structure that may function as a dynamic
#=GF CC mechanism to push secreted proteins out of the cell. The
#=GF CC polypeptide is organized into a long N-terminal alpha-helix
#=GF CC followed by a loop region that separates it from a C-terminal
#=GF CC anti-parallel beta-sheet [1].
#=GF SQ 3078
#=GS A0A0S9NTL4_9BURK/54-161 AC A0A0S9NTL4.1
#=GS A0A7C8AG57_9BACT/39-110 AC A0A7C8AG57.1
#=GS A7C780_9GAMM/32-142 AC A7C780.1
#=GS A0A0T2YDD4_9BURK/37-143 AC A0A0T2YDD4.1
#=GS A0A0Q4L7P2_9SPHN/52-159 AC A0A0Q4L7P2.1
#=GS A0A2H5X912_9BACT/34-138 AC A0A2H5X912.1
#=GS A0A178ILR5_9BACT/45-153 AC A0A178ILR5.1
#=GS A0A7L5XXU9_9HYPH/46-149 AC A0A7L5XXU9.1
#=GS A0A5B8RUR5_9BURK/39-143 AC A0A5B8RUR5.1
#=GS A0A7W7YA20_9BACT/54-158 AC A0A7W7YA20.1
#=GS A0A3M0A9W1_9GAMM/31-141 AC A0A3M0A9W1.1
#=GS B9JMF7_AGRRK/41-147 AC B9JMF7.1
#=GS A0A1T4WX99_9BACT/46-145 AC A0A1T4WX99.1
#=GS A0A853I0Z5_9GAMM/31-139 AC A0A853I0Z5.1
#=GS A0A7W8D6B7_9GAMM/15-117 AC A0A7W8D6B7.1
#=GS A0A444JBS1_9DELT/51-162 AC A0A444JBS1.1
#=GS A0A3N6MP74_9BURK/27-133 AC A0A3N6MP74.1
#=GS A0A133XLC7_9RHOO/28-122 AC A0A133XLC7.1
#=GS A0A0M2VHF2_9GAMM/31-137 AC A0A0M2VHF2.1
#=GS A0A1T1HCV3_OCELI/45-152 AC A0A1T1HCV3.1
#=GS A0A6C0U9H5_9GAMM/38-144 AC A0A6C0U9H5.1
#=GS A0A0G2ZLE6_9DELT/39-133 AC A0A0G2ZLE6.1
#=GS A0A149VZ13_9PROT/45-152 AC A0A149VZ13.1
#=GS A0A0A8WM73_9DELT/59-159 AC A0A0A8WM73.1
#=GS A0A2N5X769_9GAMM/31-140 AC A0A2N5X769.1
#=GS A0A1L6I9I4_9BURK/35-141 AC A0A1L6I9I4.1
#=GS C6XC20_METGS/38-144 AC C6XC20.1
#=GS A0A1I7JBS0_9BURK/73-180 AC A0A1I7JBS0.1
#=GS K8E061_9FIRM/32-131 AC K8E061.1
#=GS A0A6M8MTC5_9PSED/38-141 AC A0A6M8MTC5.1
#=GS A0A0Q6VTK9_9BURK/40-147 AC A0A0Q6VTK9.1
#=GS B4D870_9BACT/35-141 AC B4D870.1
#=GS A0A851GKR4_9BACT/23-120 AC A0A851GKR4.1
#=GS A0A1H2DVC6_9BACT/40-82 AC A0A1H2DVC6.1
#=GS A0A1X7AMN2_9GAMM/36-148 AC A0A1X7AMN2.1
#=GS A0A517MDL8_9BACT/41-140 AC A0A517MDL8.1
#=GS A0A2N5Y0P2_9GAMM/29-138 AC A0A2N5Y0P2.1
#=GS I5AYT0_9DELT/102-201 AC I5AYT0.1
#=GS C5T1D5_ACIDE/44-150 AC C5T1D5.1
#=GS A0A7W3FJS8_9GAMM/37-143 AC A0A7W3FJS8.1
#=GS A0A6C2UVR5_9BACT/32-126 AC A0A6C2UVR5.1
#=GS A0A2N7X2L7_9BURK/36-114 AC A0A2N7X2L7.1
#=GS A0A3N8KLX6_9BURK/49-154 AC A0A3N8KLX6.1
#=GS U7UTZ2_9FIRM/42-127 AC U7UTZ2.1
#=GS A0A126T8L4_9GAMM/33-140 AC A0A126T8L4.1
#=GS A0A2N7D172_9VIBR/33-141 AC A0A2N7D172.1
#=GS A0A238L1G5_9RHOB/34-143 AC A0A238L1G5.1
#=GS A0A1H7LPL2_9PROT/45-151 AC A0A1H7LPL2.1
#=GS A0A6I2GTB5_9DELT/50-143 AC A0A6I2GTB5.1
#=GS J9DUV5_9PROT/41-146 AC J9DUV5.1
#=GS A0A0U3F237_9BURK/47-154 AC A0A0U3F237.1
#=GS A0A515ELF0_9BURK/38-145 AC A0A515ELF0.1
#=GS A0A562WSY4_9DELT/32-143 AC A0A562WSY4.1
#=GS A0A562R209_9BURK/40-149 AC A0A562R209.1
#=GS A0A498DVF3_9PROT/37-135 AC A0A498DVF3.1
#=GS A0A437Q7P3_9GAMM/18-124 AC A0A437Q7P3.1
#=GS A0A254NA11_9BURK/32-138 AC A0A254NA11.1
#=GS A0A2S9GYS5_9BURK/83-192 AC A0A2S9GYS5.1
#=GS Q8XTG1_RALSO/39-144 AC Q8XTG1.1
#=GS F1VU06_9BURK/43-152 AC F1VU06.1
#=GS A0A1G6SMY4_9BURK/49-158 AC A0A1G6SMY4.1
#=GS A0A239BA00_9SPHN/95-204 AC A0A239BA00.1
#=GS A0A084Y6Q5_9PROT/40-146 AC A0A084Y6Q5.1
#=GS A0A0S2KFS3_9GAMM/33-142 AC A0A0S2KFS3.1
#=GS A0A257H932_9BURK/34-143 AC A0A257H932.1
#=GS A0A512MAC3_9BACT/21-118 AC A0A512MAC3.1
#=GS A0A840MU68_9PROT/31-137 AC A0A840MU68.1
#=GS A0A2R4CAK1_9BURK/29-122 AC A0A2R4CAK1.1
#=GS A0A0Q7SJ50_9BURK/36-142 AC A0A0Q7SJ50.1
#=GS A0A1H9KMA0_9PROT/39-145 AC A0A1H9KMA0.1
#=GS A0A0J1CR87_9BURK/45-154 AC A0A0J1CR87.1
#=GS A0A0A0F196_9GAMM/40-143 AC A0A0A0F196.1
#=GS A0A1G6ZEF8_9GAMM/39-141 AC A0A1G6ZEF8.1
#=GS A0A3M6QGW6_9BURK/47-157 AC A0A3M6QGW6.1
#=GS A0A0J6WV46_9FIRM/34-116 AC A0A0J6WV46.1
#=GS A0A7G9P1W0_9BACT/102-200 AC A0A7G9P1W0.1
#=GS A0A7L5Y6F3_9BURK/17-124 AC A0A7L5Y6F3.1
#=GS A0A5C5ZRL0_9BACT/42-143 AC A0A5C5ZRL0.1
#=GS B3E7L8_TRIL1/33-144 AC B3E7L8.1
#=GS A0A1M7TIR5_9BRAD/48-155 AC A0A1M7TIR5.1
#=GS A0A545T9M5_9GAMM/29-138 AC A0A545T9M5.1
#=GS A0A4R3L416_9GAMM/43-154 AC A0A4R3L416.1
#=GS L0GQ85_9GAMM/33-140 AC L0GQ85.1
#=GS B8KQM5_9GAMM/29-138 AC B8KQM5.1
#=GS A0A7T4R744_9GAMM/35-144 AC A0A7T4R744.1
#=GS A0A1N7ST88_9BURK/1-108 AC A0A1N7ST88.1
#=GS A0A1M6YQD9_9RHOB/43-152 AC A0A1M6YQD9.1
#=GS B3PF15_CELJU/37-146 AC B3PF15.1
#=GS A0A2U3I296_9BURK/46-155 AC A0A2U3I296.1
#=GS W8IJN7_ENSAD/39-146 AC W8IJN7.1
#=GS A0A0X8GKV2_9BURK/30-139 AC A0A0X8GKV2.1
#=GS A0A3M2HSQ9_9GAMM/52-156 AC A0A3M2HSQ9.1
#=GS A0A427BZS2_9GAMM/35-144 AC A0A427BZS2.1
#=GS A0A2S7WQU5_9FLAO/61-151 AC A0A2S7WQU5.1
#=GS A0A8J2Y7C7_9PROT/44-153 AC A0A8J2Y7C7.1
#=GS A0A4V2V0X4_9GAMM/34-138 AC A0A4V2V0X4.1
#=GS A0A2S0MYG8_9BURK/42-147 AC A0A2S0MYG8.1
#=GS A0A7X1AUZ4_9BACT/46-151 AC A0A7X1AUZ4.1
#=GS A0A290QC59_9BACT/42-151 AC A0A290QC59.1
#=GS A0A8A4TW14_9BACT/32-135 AC A0A8A4TW14.1
#=GS E1QGL4_DESB2/38-144 AC E1QGL4.1
#=GS B8FE45_DESAL/34-145 AC B8FE45.1
#=GS B8E075_DICTD/29-135 AC B8E075.1
#=GS A0A370DLV3_9GAMM/38-145 AC A0A370DLV3.1
#=GS A0A518DT84_9BACT/29-115 AC A0A518DT84.1
#=GS A0A157SR98_9BORD/51-157 AC A0A157SR98.1
#=GS D2TMH5_CITRI/34-140 AC D2TMH5.1
#=GS A0A160DRK4_9GAMM/40-143 AC A0A160DRK4.1
#=GS A0A5D3WIW9_9DELT/37-146 AC A0A5D3WIW9.1
#=GS A0A518DNB9_9BACT/63-172 AC A0A518DNB9.1
#=GS A0A8J7ITF3_9SPHN/47-156 AC A0A8J7ITF3.1
#=GS A0A1H8EKU4_9BURK/36-143 AC A0A1H8EKU4.1
#=GS A0A7W5ZZ52_9SPHN/40-150 AC A0A7W5ZZ52.1
#=GS A0A418WXT9_9BURK/43-152 AC A0A418WXT9.1
#=GS A0A0R0BB36_9GAMM/44-147 AC A0A0R0BB36.1
#=GS A0A8J7Q6Q5_9BACT/81-178 AC A0A8J7Q6Q5.1
#=GS A0Z787_9GAMM/29-138 AC A0Z787.1
#=GS A0A1K1RSI5_9GAMM/37-140 AC A0A1K1RSI5.1
#=GS A0A0N0K3U6_9PROT/35-142 AC A0A0N0K3U6.1
#=GS A0A2L0VLS8_9SPHN/52-162 AC A0A2L0VLS8.1
#=GS A0A0Q4MW04_9GAMM/41-147 AC A0A0Q4MW04.1
#=GS A0A1U9NKB1_9BACT/29-135 AC A0A1U9NKB1.1
#=GS Q0WIM0_YERPE/31-137 AC Q0WIM0.1
#=GS A0A7G9NYS5_9BACT/84-131 AC A0A7G9NYS5.1
#=GS A0A5K8A4R1_9DELT/37-148 AC A0A5K8A4R1.1
#=GS A0A2N7X1U4_9BURK/49-155 AC A0A2N7X1U4.1
#=GS A0A368P992_9FLAO/66-155 AC A0A368P992.1
#=GS A0A243PE32_9SPHN/69-178 AC A0A243PE32.1
#=GS A0A4Q5XGY9_9DELT/49-138 AC A0A4Q5XGY9.1
#=GS A0A7T8BCZ3_9SPIR/37-147 AC A0A7T8BCZ3.1
#=GS A0A839ILM1_9GAMM/42-149 AC A0A839ILM1.1
#=GS D9QRY4_ACEAZ/41-111 AC D9QRY4.1
#=GS A0A6P1M9B1_9BACT/40-127 AC A0A6P1M9B1.1
#=GS A0A372BYP8_9GAMM/34-143 AC A0A372BYP8.1
#=GS A0A081C793_9BACT/803-902 AC A0A081C793.1
#=GS A0A085W6H1_9DELT/48-135 AC A0A085W6H1.1
#=GS A0A3N1XAT1_9BURK/40-147 AC A0A3N1XAT1.1
#=GS A0A2C6MBE5_9FIRM/16-109 AC A0A2C6MBE5.1
#=GS A0A073J2R8_9BACT/31-140 AC A0A073J2R8.1
#=GS A0A4R3M2Q2_9HYPH/47-154 AC A0A4R3M2Q2.1
#=GS A0A5R9PBP1_9GAMM/40-142 AC A0A5R9PBP1.1
#=GS A0A254TEC7_9BURK/42-151 AC A0A254TEC7.1
#=GS A0A0N0KCS4_9SPHN/33-140 AC A0A0N0KCS4.1
#=GS A0A5S9F158_9BACT/29-124 AC A0A5S9F158.1
#=GS A0A254MZ20_9BURK/46-152 AC A0A254MZ20.1
#=GS A0A7H0GNV1_9BURK/35-142 AC A0A7H0GNV1.1
#=GS A0A2U8GVH6_9RHOO/44-151 AC A0A2U8GVH6.1
#=GS A0A6M5JAK6_9SPHN/45-155 AC A0A6M5JAK6.1
#=GS A0A6N0X3Z2_9SPHN/40-148 AC A0A6N0X3Z2.1
#=GS A0A4R6XQV5_9GAMM/32-135 AC A0A4R6XQV5.1
#=GS A0A0W0Y3F1_9GAMM/29-136 AC A0A0W0Y3F1.1
#=GS A0A1Y0ERS5_9BURK/46-151 AC A0A1Y0ERS5.1
#=GS A0A222FMJ5_9GAMM/37-146 AC A0A222FMJ5.1
#=GS A0A8J4H496_9BACL/736-812 AC A0A8J4H496.1
#=GS A0A4Y8UHF1_9GAMM/36-142 AC A0A4Y8UHF1.1
#=GS A0A542LVN2_9BURK/39-149 AC A0A542LVN2.1
#=GS A0A657B609_9GAMM/37-146 AC A0A657B609.1
#=GS A0A437NFW9_9HYPH/28-135 AC A0A437NFW9.1
#=GS A0A7W8HKM7_9BURK/40-147 AC A0A7W8HKM7.1
#=GS G3IW99_METTV/49-156 AC G3IW99.1
#=GS A0A7U6JHP7_9GAMM/34-132 AC A0A7U6JHP7.1
#=GS A0A7Y6ZVS4_9ALTE/32-138 AC A0A7Y6ZVS4.1
#=GS A0A4Z0WIF9_9GAMM/33-140 AC A0A4Z0WIF9.1
#=GS A0A2Z3HJU1_9BACT/40-144 AC A0A2Z3HJU1.1
#=GS A0A0B6S9T8_BURPL/38-147 AC A0A0B6S9T8.1
#=GS A0A1D3RLZ1_9BACT/33-140 AC A0A1D3RLZ1.1
#=GS A0A0W0V8Y6_9GAMM/29-136 AC A0A0W0V8Y6.1
#=GS H0PY82_9RHOO/38-144 AC H0PY82.1
#=GS A0A6F8PST9_9GAMM/34-141 AC A0A6F8PST9.1
#=GS Q0ASR0_MARMM/42-149 AC Q0ASR0.1
#=GS A0A1E4QRS8_9BURK/50-159 AC A0A1E4QRS8.1
#=GS A0A5R8KDB3_9BACT/45-149 AC A0A5R8KDB3.1
#=GS A0A8J7MFP2_9BACT/42-150 AC A0A8J7MFP2.1
#=GS G2E1L5_9GAMM/34-141 AC G2E1L5.1
#=GS A0A370G185_9COXI/38-143 AC A0A370G185.1
#=GS A0A846VWJ3_9RHOB/41-150 AC A0A846VWJ3.1
#=GS A0A7H9BP82_9NEIS/33-140 AC A0A7H9BP82.1
#=GS A0A5C4NBP3_9RHOB/35-142 AC A0A5C4NBP3.1
#=GS A0A4S2HBG0_9PROT/39-148 AC A0A4S2HBG0.1
#=GS A0A0U2RPH1_9ALTE/30-135 AC A0A0U2RPH1.1
#=GS B0SR84_LEPBP/36-142 AC B0SR84.1
#=GS I3IID7_9BACT/37-144 AC I3IID7.1
#=GS H8GIG6_METAL/39-146 AC H8GIG6.1
#=GS A0A4U0QRC2_9NEIS/33-139 AC A0A4U0QRC2.1
#=GS F3LEQ3_9GAMM/39-148 AC F3LEQ3.1
#=GS F4G706_ALIDK/27-134 AC F4G706.1
#=GS A0A7Z2GJK7_9BURK/49-158 AC A0A7Z2GJK7.1
#=GS A0A1H9EXI8_9SPIR/48-170 AC A0A1H9EXI8.1
#=GS A0A1H3WPQ6_9RHOB/51-158 AC A0A1H3WPQ6.1
#=GS A0A3Q9HPL8_9FIRM/36-147 AC A0A3Q9HPL8.1
#=GS A0A7U7J2X1_9GAMM/35-142 AC A0A7U7J2X1.1
#=GS A0A257IRX3_9BURK/40-120 AC A0A257IRX3.1
#=GS A0A7C9PJR0_9BURK/47-154 AC A0A7C9PJR0.1
#=GS B8E077_DICTD/29-122 AC B8E077.1
#=GS A0A5S9IRI6_9BACT/37-126 AC A0A5S9IRI6.1
#=GS A0A3N1XTJ3_9GAMM/29-134 AC A0A3N1XTJ3.1
#=GS A0A8J6T1K0_9PROT/46-147 AC A0A8J6T1K0.1
#=GS A0A521G0W2_9DELT/37-148 AC A0A521G0W2.1
#=GS N1MU64_9SPHN/69-178 AC N1MU64.1
#=GS A0A1M5PTH9_9GAMM/26-135 AC A0A1M5PTH9.1
#=GS A0A2S5SV96_9BURK/42-149 AC A0A2S5SV96.1
#=GS A0A0A0HGX9_9RHOB/40-149 AC A0A0A0HGX9.1
#=GS A0A370N8P6_9BURK/44-153 AC A0A370N8P6.1
#=GS B5JVD1_9GAMM/37-144 AC B5JVD1.1
#=GS A0A6C2UGV5_9BACT/42-163 AC A0A6C2UGV5.1
#=GS A0A0D6SYY1_9PSED/34-139 AC A0A0D6SYY1.1
#=GS A0A1V4CCK0_9BURK/39-146 AC A0A1V4CCK0.1
#=GS A0A841R519_9SPIO/45-152 AC A0A841R519.1
#=GS A0A6G8D607_9VIBR/37-145 AC A0A6G8D607.1
#=GS A0A840BGK6_9RHOO/46-153 AC A0A840BGK6.1
#=GS A0A848F4E5_9BURK/36-143 AC A0A848F4E5.1
#=GS A0A0C5VZM0_9GAMM/31-138 AC A0A0C5VZM0.1
#=GS W1S4G7_9SPHN/71-180 AC W1S4G7.1
#=GS A0A8J7WZH4_9GAMM/35-138 AC A0A8J7WZH4.1
#=GS J7IS53_DESMD/29-111 AC J7IS53.1
#=GS A0A7X0QM90_9GAMM/44-153 AC A0A7X0QM90.1
#=GS A0A3N7HZ72_9BURK/41-148 AC A0A3N7HZ72.1
#=GS A0A4P6VT95_9GAMM/36-144 AC A0A4P6VT95.1
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