#=GF ID T2SSK_1st
#=GF AC PF21687.1
#=GF DE Type II secretion system (T2SS), protein K
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Desvaux M;0000-0003-2986-6417
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE COG3156
#=GF GA 26.20 26.20;
#=GF TC 26.20 26.20;
#=GF NC 26.10 26.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0198
#=GF RN [1]
#=GF RM 15223057
#=GF RT The general secretory pathway: a general misnomer?.
#=GF RA Desvaux M, Parham NJ, Scott-Tucker A, Henderson IR;
#=GF RL Trends Microbiol. 2004;12:306-309.
#=GF RN [2]
#=GF RM 14600218
#=GF RT Type II protein secretion and its relationship to bacterial type
#=GF RT IV pili and archaeal flagella.
#=GF RA Peabody CR, Chung YJ, Yen MR, Vidal-Ingigliardi D, Pugsley AP,
#=GF RA Saier MH Jr;
#=GF RL Microbiology. 2003;149:3051-3072.
#=GF RN [3]
#=GF RM 19299134
#=GF RT Secretion and subcellular localizations of bacterial proteins: a
#=GF RT semantic awareness issue.
#=GF RA Desvaux M, Hebraud M, Talon R, Henderson IR;
#=GF RL Trends Microbiol. 2009;17:139-145.
#=GF DR TC; 3.A.15;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Members of this family are involved in the Type II protein
#=GF CC secretion system. The T2SK family includes proteins such as
#=GF CC ExeK, PulK, OutX and XcpX. They consist of two tandem SAM-like
#=GF CC domains, this entry represents the first one.
#=GF SQ 1915
#=GS W0AF25_9SPHN/108-218 AC W0AF25.1
#=GS A0A0Q7R951_9CAUL/105-214 AC A0A0Q7R951.1
#=GS A0A0A0HEU6_9RHOB/105-199 AC A0A0A0HEU6.1
#=GS A0A1E7Q213_9GAMM/96-199 AC A0A1E7Q213.1
#=GS A0A1Q2MFG1_9BACT/97-190 AC A0A1Q2MFG1.1
#=GS A0A850QJ84_9BURK/81-184 AC A0A850QJ84.1
#=GS K6H494_9GAMM/83-194 AC K6H494.1
#=GS A0A832USZ0_9BACT/133-234 AC A0A832USZ0.1
#=GS W9TAC5_9PSED/96-210 AC W9TAC5.1
#=GS C0QLU2_DESAH/114-220 AC C0QLU2.1
#=GS A0A518G343_9BACT/181-316 AC A0A518G343.1
#=GS A0A562IKQ0_9GAMM/104-205 AC A0A562IKQ0.1
#=GS A0A4V3DNK5_9GAMM/92-199 AC A0A4V3DNK5.1
#=GS A0A1M5FAX5_9ALTE/103-216 AC A0A1M5FAX5.1
#=GS A0A1W1XZI4_9NEIS/92-185 AC A0A1W1XZI4.1
#=GS A0A7Y9IPW3_9BURK/109-233 AC A0A7Y9IPW3.1
#=GS A0A2U3QIC8_9BACT/114-201 AC A0A2U3QIC8.1
#=GS A0A1M6YPM5_9RHOB/101-195 AC A0A1M6YPM5.1
#=GS A0A1H8IZ07_9BURK/129-220 AC A0A1H8IZ07.1
#=GS A0A2N5EHW8_9GAMM/101-210 AC A0A2N5EHW8.1
#=GS A0A840S7S5_9BURK/84-174 AC A0A840S7S5.1
#=GS A0A0K0XTD0_9GAMM/100-202 AC A0A0K0XTD0.1
#=GS A0A1W6LP60_9BACT/111-192 AC A0A1W6LP60.1
#=GS A0A0F3GP67_9BACT/91-207 AC A0A0F3GP67.1
#=GS A0A4Q1K084_9GAMM/95-204 AC A0A4Q1K084.1
#=GS A0A4R6DWK6_9RHOO/80-183 AC A0A4R6DWK6.1
#=GS A0A0R0CX58_9GAMM/85-193 AC A0A0R0CX58.1
#=GS A0A5K8A4T2_9DELT/121-228 AC A0A5K8A4T2.1
#=GS A0A7T0JQM7_9GAMM/100-203 AC A0A7T0JQM7.1
#=GS A0A512DS54_9PROT/71-198 AC A0A512DS54.1
#=GS A0A378I1J3_9GAMM/112-214 AC A0A378I1J3.1
#=GS A0A154NAN6_9SPHN/104-216 AC A0A154NAN6.1
#=GS A0A8J3DG50_9BACT/107-202 AC A0A8J3DG50.1
#=GS A0A5A7MVP2_9PROT/100-204 AC A0A5A7MVP2.1
#=GS A0A7C8AMP4_9BACT/8-97 AC A0A7C8AMP4.1
#=GS A0A1E8CLM8_9GAMM/124-214 AC A0A1E8CLM8.1
#=GS A0A4Y4CQT7_ZOORA/110-216 AC A0A4Y4CQT7.1
#=GS A0A4U0PZ19_9NEIS/141-243 AC A0A4U0PZ19.1
#=GS A0A6S7DIS4_9BURK/154-284 AC A0A6S7DIS4.1
#=GS A0A4Q8QRL8_9BRAD/89-210 AC A0A4Q8QRL8.1
#=GS A0A5C6E2R2_9BACT/126-238 AC A0A5C6E2R2.1
#=GS Q12DW7_POLSJ/114-203 AC Q12DW7.1
#=GS I3IQK5_9BACT/107-206 AC I3IQK5.1
#=GS A0A0T6UPD2_9PSED/105-207 AC A0A0T6UPD2.1
#=GS A0A1S8CE22_9GAMM/102-210 AC A0A1S8CE22.1
#=GS S6AE25_PSERE/105-207 AC S6AE25.1
#=GS A0A1P8FQP5_9PROT/102-205 AC A0A1P8FQP5.1
#=GS A0A366EQK1_9HYPH/98-199 AC A0A366EQK1.1
#=GS A0A418XQH7_9BURK/116-214 AC A0A418XQH7.1
#=GS A0A4P7XHE2_9ALTE/109-212 AC A0A4P7XHE2.1
#=GS A0A370Q889_9GAMM/100-201 AC A0A370Q889.1
#=GS B1ZTV8_OPITP/136-225 AC B1ZTV8.1
#=GS A0A257JKU0_9PROT/98-202 AC A0A257JKU0.1
#=GS A0A3P1XJP1_9BURK/137-233 AC A0A3P1XJP1.1
#=GS A0A4P8IRG1_9BURK/125-260 AC A0A4P8IRG1.1
#=GS A0A7U7ERF1_9PSED/105-207 AC A0A7U7ERF1.1
#=GS A0A4U0GBY6_9GAMM/117-225 AC A0A4U0GBY6.1
#=GS Q6D2J3_PECAS/102-213 AC Q6D2J3.1
#=GS A0A1S9A9C5_9BURK/121-240 AC A0A1S9A9C5.1
#=GS Q88P11_PSEPK/101-199 AC Q88P11.1
#=GS A0A1X7AGU4_9GAMM/101-207 AC A0A1X7AGU4.1
#=GS A0A6C2USF0_9BACT/141-234 AC A0A6C2USF0.1
#=GS A0A518IXU1_9BACT/155-267 AC A0A518IXU1.1
#=GS A0A171KT28_9BURK/110-197 AC A0A171KT28.1
#=GS A0A0Q4Y7J9_9BURK/108-196 AC A0A0Q4Y7J9.1
#=GS A0A5P9C5Q8_9PSED/105-207 AC A0A5P9C5Q8.1
#=GS A0A3N6PV88_9BURK/159-293 AC A0A3N6PV88.1
#=GS A0A1G6U1F9_9BURK/136-270 AC A0A1G6U1F9.1
#=GS A0A1B2LYG4_9GAMM/103-206 AC A0A1B2LYG4.1
#=GS A0A8J6IU35_9ALTE/102-216 AC A0A8J6IU35.1
#=GS A0A562ZF94_9BURK/117-207 AC A0A562ZF94.1
#=GS A6T4U2_KLEP7/91-200 AC A6T4U2.1
#=GS A0A1I6MCU6_9GAMM/100-201 AC A0A1I6MCU6.1
#=GS A0A0F4PU73_9GAMM/104-209 AC A0A0F4PU73.1
#=GS W0BEW0_9GAMM/102-204 AC W0BEW0.1
#=GS A0A2A4IEI5_9SPHN/80-184 AC A0A2A4IEI5.1
#=GS A0A6M1RP18_9BACT/116-202 AC A0A6M1RP18.1
#=GS A0A317EE80_9PROT/111-214 AC A0A317EE80.1
#=GS A0A0F3ILN6_9GAMM/12-93 AC A0A0F3ILN6.1
#=GS G8QCH8_PSEO1/109-224 AC G8QCH8.1
#=GS A0A0W0U528_9GAMM/105-206 AC A0A0W0U528.1
#=GS A0A8F1WG44_9BACT/105-209 AC A0A8F1WG44.1
#=GS A0A4Y7ZV43_9GAMM/100-208 AC A0A4Y7ZV43.1
#=GS A0A4V3CQ24_9GAMM/105-213 AC A0A4V3CQ24.1
#=GS A0A157SNC8_9BORD/111-227 AC A0A157SNC8.1
#=GS A0A2K9LFN2_9GAMM/129-241 AC A0A2K9LFN2.1
#=GS A0A3N7C901_9BURK/124-221 AC A0A3N7C901.1
#=GS A0A1H9KCQ4_9BURK/129-183 AC A0A1H9KCQ4.1
#=GS A0A243PFI1_9SPHN/106-216 AC A0A243PFI1.1
#=GS A0A090AH20_9GAMM/103-205 AC A0A090AH20.1
#=GS A0A5C6UD45_9SPHN/114-224 AC A0A5C6UD45.1
#=GS A0A514X1R8_9PROT/121-240 AC A0A514X1R8.1
#=GS A0A0F3GVM5_9BACT/99-205 AC A0A0F3GVM5.1
#=GS A0A517SY84_9BACT/139-251 AC A0A517SY84.1
#=GS A0A1T4VXR1_9GAMM/72-175 AC A0A1T4VXR1.1
#=GS A0A7W9W821_9BACT/113-191 AC A0A7W9W821.1
#=GS A0A126T8J5_9GAMM/96-200 AC A0A126T8J5.1
#=GS A0A516V7G4_9GAMM/88-192 AC A0A516V7G4.1
#=GS A0A0S4M2X1_9BURK/105-192 AC A0A0S4M2X1.1
#=GS A0A0W0YQL8_9GAMM/105-207 AC A0A0W0YQL8.1
#=GS A0A1P8FHN1_9PROT/98-202 AC A0A1P8FHN1.1
#=GS A0A1V6LY26_9BACT/152-251 AC A0A1V6LY26.1
#=GS A8G1I0_SHESH/106-218 AC A8G1I0.1
#=GS A0A2S4M4U0_9BURK/130-266 AC A0A2S4M4U0.1
#=GS A0A840RX44_9BURK/121-208 AC A0A840RX44.1
#=GS A3UEW9_9PROT/104-222 AC A3UEW9.1
#=GS A0A7D5MW76_9PROT/121-222 AC A0A7D5MW76.1
#=GS A0A327XZB0_9RHOB/98-196 AC A0A327XZB0.1
#=GS A0A1I4WX59_9GAMM/104-207 AC A0A1I4WX59.1
#=GS A0A0S2F6Y5_LYSAN/75-183 AC A0A0S2F6Y5.1
#=GS A0A059F9A3_9PROT/105-213 AC A0A059F9A3.1
#=GS A0A1G9LVC2_9PROT/105-215 AC A0A1G9LVC2.1
#=GS A0A3A6UM94_9GAMM/106-222 AC A0A3A6UM94.1
#=GS A6CD19_9PLAN/140-228 AC A6CD19.1
#=GS B9TK73_RICCO/83-200 AC B9TK73.1
#=GS U1KKV0_9GAMM/101-216 AC U1KKV0.1
#=GS A0A2N0WZV9_9GAMM/100-208 AC A0A2N0WZV9.1
#=GS A0A1V2ES28_9SPHN/105-212 AC A0A1V2ES28.1
#=GS Q5H4L4_XANOR/106-210 AC Q5H4L4.1
#=GS H0TIA5_9BRAD/84-185 AC H0TIA5.1
#=GS A0A1Q2SK82_9GAMM/100-201 AC A0A1Q2SK82.1
#=GS A0A1H9HU69_9GAMM/101-209 AC A0A1H9HU69.1
#=GS A0A1N6GQY6_9BURK/133-228 AC A0A1N6GQY6.1
#=GS M4VRD5_9PROT/148-263 AC M4VRD5.1
#=GS A0A5Q2K5W8_9ENTR/103-219 AC A0A5Q2K5W8.1
#=GS A0A2R7IHX9_9SPHN/107-217 AC A0A2R7IHX9.1
#=GS A0A239L6D2_9SPHN/105-215 AC A0A239L6D2.1
#=GS A0A1Y6EM74_9GAMM/105-216 AC A0A1Y6EM74.1
#=GS A0A4R5TPT9_9GAMM/86-189 AC A0A4R5TPT9.1
#=GS A0A8J7X2D5_9GAMM/93-196 AC A0A8J7X2D5.1
#=GS A0A2M6VMQ3_9BURK/131-217 AC A0A2M6VMQ3.1
#=GS A0A318EL56_9GAMM/106-214 AC A0A318EL56.1
#=GS A0YG40_9GAMM/88-201 AC A0YG40.1
#=GS A0A0L6VW52_9BURK/121-257 AC A0A0L6VW52.1
#=GS A0A4R1KF13_9GAMM/102-207 AC A0A4R1KF13.1
#=GS A0A345P676_9GAMM/122-225 AC A0A345P676.1
#=GS A0A177N140_9GAMM/104-206 AC A0A177N140.1
#=GS A0A1H7RAG2_9GAMM/106-222 AC A0A1H7RAG2.1
#=GS A6GLQ2_9BURK/121-218 AC A6GLQ2.1
#=GS A0A7J7BRX2_9COLE/424-527 AC A0A7J7BRX2.1
#=GS A0A094LNA6_9GAMM/103-216 AC A0A094LNA6.1
#=GS S9P5W7_9DELT/169-298 AC S9P5W7.1
#=GS A0A1P8WCC6_9PLAN/181-277 AC A0A1P8WCC6.1
#=GS A0A1H0M265_9DELT/107-212 AC A0A1H0M265.1
#=GS F3LEP9_9GAMM/125-244 AC F3LEP9.1
#=GS A0A396U958_9GAMM/104-247 AC A0A396U958.1
#=GS A0A193LG17_9GAMM/107-210 AC A0A193LG17.1
#=GS A0A225E4E4_9BACT/158-245 AC A0A225E4E4.1
#=GS A0A5B2ZCZ1_9GAMM/87-192 AC A0A5B2ZCZ1.1
#=GS A0A2H6B490_9BACT/88-188 AC A0A2H6B490.1
#=GS A0A068NXT8_FIMGI/115-194 AC A0A068NXT8.1
#=GS Q1JVU8_DESA6/108-212 AC Q1JVU8.1
#=GS A0A085A4M2_9ENTR/100-208 AC A0A085A4M2.1
#=GS C4L991_TOLAT/101-213 AC C4L991.1
#=GS A0A4Z0M4H3_9GAMM/96-212 AC A0A4Z0M4H3.1
#=GS A0A4Y9SFY0_9BURK/124-239 AC A0A4Y9SFY0.1
#=GS N9W549_9SPHN/105-215 AC N9W549.1
#=GS A0A411PMW8_9GAMM/103-215 AC A0A411PMW8.1
#=GS A0A2U1C7J0_9BURK/121-208 AC A0A2U1C7J0.1
#=GS A0A7Y9QUP7_9BURK/121-217 AC A0A7Y9QUP7.1
#=GS D3DH18_HYDTT/84-170 AC D3DH18.1
#=GS A0A257DNC8_9SPHN/104-213 AC A0A257DNC8.1
#=GS A0A1Q2M4P5_9GAMM/110-244 AC A0A1Q2M4P5.1
#=GS A0A812RN33_9DINO/1-52 AC A0A812RN33.1
#=GS K6ZVW5_9ALTE/104-220 AC K6ZVW5.1
#=GS A9GDP8_SORC5/170-290 AC A9GDP8.1
#=GS A0A0N7J885_9BURK/121-219 AC A0A0N7J885.1
#=GS A0A316I8Q5_9GAMM/91-191 AC A0A316I8Q5.1
#=GS A0A2S7K2T8_9PROT/104-212 AC A0A2S7K2T8.1
#=GS A0A0K2GD56_NITMO/107-211 AC A0A0K2GD56.1
#=GS A0A146G9Z1_TERSA/94-185 AC A0A146G9Z1.1
#=GS A0A257M040_9BACT/33-124 AC A0A257M040.1
#=GS A0A1D3RLH7_9BACT/82-191 AC A0A1D3RLH7.1
#=GS A0A7Y6ZUK6_9ALTE/85-188 AC A0A7Y6ZUK6.1
#=GS A0A2R4XKP8_9BURK/166-253 AC A0A2R4XKP8.1
#=GS A0A0H3GJJ1_KLEPH/91-200 AC A0A0H3GJJ1.1
#=GS A0A516SGF6_9BURK/115-205 AC A0A516SGF6.1
#=GS A0A081N7C1_9GAMM/110-211 AC A0A081N7C1.1
#=GS A0A845HYG2_9BURK/116-244 AC A0A845HYG2.1
#=GS A0A7L5XXY6_9HYPH/94-193 AC A0A7L5XXY6.1
#=GS A0A7W6MMC5_9HYPH/95-203 AC A0A7W6MMC5.1
#=GS A0A6N0WZU0_9SPHN/103-211 AC A0A6N0WZU0.1
#=GS A0A135ZYU4_9ALTE/96-202 AC A0A135ZYU4.1
#=GS I3CFQ6_9GAMM/94-202 AC I3CFQ6.1
#=GS B4D856_9BACT/91-177 AC B4D856.1
#=GS A0A150WM40_BDEBC/120-238 AC A0A150WM40.1
#=GS A0A845FME0_9GAMM/109-210 AC A0A845FME0.1
#=GS A0A1D9HCI2_9BURK/125-214 AC A0A1D9HCI2.1
#=GS A0A4R4ELG9_9GAMM/91-196 AC A0A4R4ELG9.1
#=GS A0A1H1KKY1_9HYPH/113-215 AC A0A1H1KKY1.1
#=GS E0UU12_SULAO/101-210 AC E0UU12.1
#=GS A0A5C6M3Y8_9PLAN/129-219 AC A0A5C6M3Y8.1
#=GS A0A7T0JSD0_9GAMM/103-205 AC A0A7T0JSD0.1
#=GS I3CIQ4_9GAMM/130-216 AC I3CIQ4.1
#=GS W0E355_MARPU/98-196 AC W0E355.1
#=GS A0A6C0U324_9GAMM/117-235 AC A0A6C0U324.1
#=GS A4A5K4_9GAMM/119-231 AC A4A5K4.2
#=GS D6CMZ0_THIA3/147-239 AC D6CMZ0.1
#=GS A0A369WK00_9GAMM/98-210 AC A0A369WK00.1
#=GS A0A1S8DIQ6_9GAMM/100-199 AC A0A1S8DIQ6.1
#=GS A0A103EIG6_9BURK/131-261 AC A0A103EIG6.1
#=GS A0A369T9P7_9PROT/108-211 AC A0A369T9P7.1
#=GS A0A5K7X6P1_9BACT/134-223 AC A0A5K7X6P1.1
#=GS A0A5P1R802_9GAMM/95-206 AC A0A5P1R802.1
#=GS A0A7C9PIH5_9BURK/136-238 AC A0A7C9PIH5.1
#=GS A0A507ZTY9_9GAMM/97-201 AC A0A507ZTY9.1
#=GS A0A517T5H7_9PLAN/130-217 AC A0A517T5H7.1
#=GS A0A2Z6E7S8_9GAMM/95-192 AC A0A2Z6E7S8.1
#=GS A0A0W0VK21_9GAMM/150-252 AC A0A0W0VK21.1
#=GS A0A0F4P852_PSEO7/98-195 AC A0A0F4P852.1
#=GS A0A202DJP1_9BACT/101-196 AC A0A202DJP1.1
#=GS A0A1G6BGG1_9GAMM/116-228 AC A0A1G6BGG1.1
#=GS A0A842HKV0_9BACT/198-291 AC A0A842HKV0.1
#=GS A0A848HP01_9BURK/116-213 AC A0A848HP01.1
#=GS A0A1B2R8D0_9BORD/100-203 AC A0A1B2R8D0.1
#=GS A0A0N0GR57_9NEIS/111-214 AC A0A0N0GR57.1
#=GS A0A8J7IB92_9SPHN/110-220 AC A0A8J7IB92.1
#=GS A0A1H8AVK9_9DELT/107-207 AC A0A1H8AVK9.1
#=GS F2K4G9_MARM1/109-209 AC F2K4G9.1
#=GS A0A220VD30_9GAMM/113-217 AC A0A220VD30.1
#=GS A0A4V3RZ66_9PROT/111-226 AC A0A4V3RZ66.1
#=GS A0A315WM63_9PSED/101-199 AC A0A315WM63.1
#=GS A0A1H3BIH6_9GAMM/112-215 AC A0A1H3BIH6.1
#=GS A0A6J5G2E1_9BURK/135-268 AC A0A6J5G2E1.1
#=GS A0A385Z476_9PSED/105-207 AC A0A385Z476.1
#=GS A0A5S9R2K9_9GAMM/110-233 AC A0A5S9R2K9.1
#=GS A0A191ZHU2_9GAMM/114-212 AC A0A191ZHU2.1
#=GS A0A6F9WV48_9DELT/103-205 AC A0A6F9WV48.1
#=GS A0A2N3PQC4_9PROT/195-302 AC A0A2N3PQC4.1
#=GS A0A0N1LR17_9SPHN/108-218 AC A0A0N1LR17.1
#=GS A0A0C9PIZ0_9BACT/25-124 AC A0A0C9PIZ0.1
#=GS A0A069PHI1_9BURK/124-260 AC A0A069PHI1.1
#=GS A0A858RNS0_9BACT/95-186 AC A0A858RNS0.1
#=GS A0A1H7RMI7_9GAMM/104-206 AC A0A1H7RMI7.1
#=GS A0A517TK18_9BACT/116-207 AC A0A517TK18.1
#=GS A0A0A2X6H2_9GAMM/83-191 AC A0A0A2X6H2.1
#=GS A0A090I8U8_9GAMM/103-211 AC A0A090I8U8.1
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