#=GF ID   T4-Gluco-transf
#=GF AC   PF09198.14
#=GF DE   Bacteriophage T4 beta-glucosyltransferase
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1jix
#=GF GA   27.00 27.00;
#=GF TC   32.20 76.80;
#=GF NC   26.20 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF WK   DNA_beta-glucosyltransferase
#=GF CL   CL0113
#=GF RN   [1]
#=GF RM   11493010
#=GF RT   High resolution crystal structures of T4 phage
#=GF RT   beta-glucosyltransferase: induced fit and effect of substrate
#=GF RT   and metal binding. 
#=GF RA   Morera S, Lariviere L, Kurzeck J, Aschke-Sonnenborn U, Freemont
#=GF RA   PS, Janin J, Ruger W; 
#=GF RL   J Mol Biol. 2001;311:569-577.
#=GF RN   [2]
#=GF RM   22229759
#=GF RT   Biochemical characterization of recombinant
#=GF RT   beta-glucosyltransferase and analysis of global
#=GF RT   5-hydroxymethylcytosine in unique genomes.
#=GF RA   Terragni J, Bitinaite J, Zheng Y, Pradhan S;
#=GF RL   Biochemistry. 2012;51:1009-1019.
#=GF DR   INTERPRO; IPR015281;
#=GF DR   SCOP; 1jix; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family are DNA-modifying enzymes encoded by
#=GF CC   bacteriophage T4 that transfer glucose from uridine
#=GF CC   diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4
#=GF CC   DNA [1]. It is involved in a DNA modification process to protect
#=GF CC   the phage genome against its own nucleases and the host
#=GF CC   restriction endonuclease system [2].
#=GF SQ   14
#=GS A0A0A0YVB4_9CAUD/1-172   AC A0A0A0YVB4.1
#=GS A0A5P8PH34_9CAUD/1-165   AC A0A5P8PH34.1
#=GS A0A7T5QVI2_9CAUD/1-173   AC A0A7T5QVI2.1
#=GS A0A8D4GMV9_9CAUD/38-187  AC A0A8D4GMV9.1
#=GS A0A1D3RKN8_9CAUD/1-172   AC A0A1D3RKN8.1
#=GS GSTB_BPT4/1-166          AC P04547.1
#=GS A0A2H4YFI2_9CAUD/1-172   AC A0A2H4YFI2.1
#=GS K4I219_9CAUD/1-172       AC K4I219.1
#=GS E5DI50_9CAUD/1-172       AC E5DI50.1
#=GS A0A6G9LKQ5_9CAUD/1-166   AC A0A6G9LKQ5.1
#=GS A0A4Y5FF44_9CAUD/3-169   AC A0A4Y5FF44.1
#=GS M1EAF1_BPS16/1-172       AC M1EAF1.1
#=GS A0A023W4X1_9CAUD/1-165   AC A0A023W4X1.1
#=GS A0A0K1LN97_9CAUD/1-140   AC A0A0K1LN97.1
A0A0A0YVB4_9CAUD/1-172              .............................MKIAIINMGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKNTQY..GISFDSVEDPN..VYDRLLVVNAALNFYGGEENAMNKAAYMFMNKYKSKIYYLFTDIRLPFEQAWRRMSKKKWSSKYKEEQFIVT.SPMRIVSQGRDLEQAKRIHSEr...lV.GcqfG....KL.EF.THFALDRHK......
A0A5P8PH34_9CAUD/1-165              .............................MKIALLNLANNVTGYKTTPSGETLYMASALRDMGYEVDVISNKPSDD..VVSFEQVSDIN..SYDHLLVIGGAINFFGGKESPTIINNYKLMAQYKGTINYLLTDIRLTFNQLWPAIEHRGWGY--EKDEVWIS.SPVNIISQGYDLETIRKVHSK.....V.Q...A....AI.TY.RYFPLERYK......
A0A7T5QVI2_9CAUD/1-173              .............................MKIAIINMGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKNTQY..GISFDSVEDPN..VYDRLLVVNAALNFYGGEENKMNKEAYMFMNKYKSKIYYLFTDIRLPFEQAWRRMQKKKWSSKYKEEQFIVT.APMRIVSQGRDLEQAKRIHSEr...lV.G...AcqygKL.EF.THFALDRH-k.....
A0A8D4GMV9_9CAUD/38-187             agaevhaytkvlakesfnptpglimhqig-----------------------------------------------..----DEYKDVNaqDYDALCIINGNINYFGGLDDPTQTIIYDIINNFKGKVFYLYCDPNLTLKQAWPTIEKKPWANDYERKNIEITrEDITVISQSYNLDHVKTAFDK.....T.G...I....RIkDF.KQYAFEK--fpl...
A0A1D3RKN8_9CAUD/1-172              .............................MKIAILNLGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKQTIY..GIAFDDVPDPN..VYDRVLVVNASLNFYGGEENKMNKAAYMFLNKYKSKIYYLFTDIRLPWEQAWRRMSKKKWSSKYTEEQFIVR.SPIRVISQGRDLEQAKRIHSDrlvgiS.K...D....RM.EF.VHFALDRHK......
GSTB_BPT4/1-166                     .............................MKIAIINMGNNVINFKTVPSSETIYLFKVISEMGLNVDIISLKNGVY..TKSFDEV-DVN..DYDRLIVVNSSINFFGGKPNLAILSAQKFMAKYKSKIYYLFTDIRLPFSQSWPNVKNRPWAYLYTEEELLIK.SPIKVISQGINLDIAKAAHKK.....V.D...N....VI.EF.EYFPIEQYK......
A0A2H4YFI2_9CAUD/1-172              .............................MKIAIINMGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKNTQY..GISFDSVEDPN..VYDRLLVVNAALNFYGGEENAMNKAAYMFMNKYKSKIYYLFTDIRLPFEQAWRRMSKKKWSSKYKEEQFIVT.SPMRIVSQGRDLEQAKRIHSEr...lV.GcqfG....KL.EF.THFALDRHK......
K4I219_9CAUD/1-172                  .............................MKIAIINMGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKNTQY..GISFDSVKDPN..VYDRLLVVNAALNFYGGEENKMNKEAYMFMNKYKSKIYYLFTDIRLPFEQAWRRMSKKKWSSKYKEEQFIVT.SPMRIVSQGRNLEQCKKIHSDrlvgcL.S...D....KL.EF.VHFALDRHK......
E5DI50_9CAUD/1-172                  .............................MKIAILNLGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKQTIY..GIAFDDVPDPN..VYDRVLVVNASLNFYGGEENKMNKAAYMFLNKYKSKIYYLFTDIRLPWEQAWRRMSKKKWSSKYTEEQFIVR.SPIRVISQGRDLEQAKRIHSDrl.vgVsK...D....RM.EF.VHFALDRHK......
A0A6G9LKQ5_9CAUD/1-166              .............................MEILLLNVANNITDFRTVSSGETVYLKQMLEQLGHGVTIASNKNGEY..AVAFEEIEDIN..NFDKVVVLPASLNFFGGVENPTIIKNYKLLAKYNGTINILQTDARLPFKQLWPAIEKRGWGY--KKEEVWIN.APIKVIAQSKNLDEVKTQYEK....eI.F...N....NI.EF.THFPIERY-a.....
A0A4Y5FF44_9CAUD/3-169              ............................e-KIALINTTNSISKRWTTPTNEVMGVKMMLNDLNYSVDVISKYRDDNlgIVSVDDVNDLN..HYDKVLIIPGTFAFYHSDPKGFIFKIYSLLAKVKNPIYVLSTDVTVPLKQLYKQAQ-RFMDI--SEKDINIS.APIKFISLNQDSEVNNRLVDE.....N.E...F....NV.AWkKYF------nfdifa
M1EAF1_BPS16/1-172                  .............................MKIAIINMGNNIQGFKTTPASETIYLSECLKDMGLDVDLISMKNTQY..GISFDSVKDPN..VYDRLLVVNAALNFYGGEENKMNKEAYMFMNKYKSKIYYLFTDIRLPFEQAWRRMSKKKWSSKYKEEQFIVT.SPMRIVSQGRNLEQCKKIHSDrlvgcL.S...D....KL.EF.VHFALDRHK......
A0A023W4X1_9CAUD/1-165              .............................MKIALLNLANNVTGYKTTPSGETLYMASALRDMGYEVDVISNKPSDD..VVSFDQVTDIN..YYDHLLVIGGAINFFGGKESPTIINNYKLMAQYKGTINYLLTDIRLTFNQLWPAISGRGWGY--EKEEVWIT.SPVNIISQGYDLETIRKVHSK.....V.E...A....DI.SY.VYFPLERYK......
A0A0K1LN97_9CAUD/1-140              .............................--------------------------------MGLDVDLISMKNTQY..GISFDSVEDPN..VYDRLLVVNAALNFYGGEENAMNKAAYMFMNKYKSKIYYLFTDIRLPFEQAWRRMSKKKWSSKYKEEQFIVT.APMRIVSQGRDLEQAKRIHSEr...lV.GcqfG....KL.EF.THFALDRHK......
#=GC seq_cons                       .............................MKIAllNhuNNIpGFKTTPuuETlYLupsL+DMGL-VDlIShKsopY..ulSFDsVpDsN..sYDRLLVVNAuLNFYGG-ENthpptAYhFMNKYKSKIYYLFTDIRLPFcQAW+phpKKtWuscYcEEphllo.SPh+llSQG+DLEpsK+lHS-.....l.t...s....+l.EF.sHFAL-RaK......
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