#=GF ID   TBD
#=GF AC   PF12845.11
#=GF DE   TBD domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Masci AM;0000-0003-1940-6740
#=GF SE   [1]
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.10;
#=GF NC   26.90 26.80;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17568778
#=GF RT   SINTBAD, a novel component of innate antiviral immunity, shares
#=GF RT   a TBK1-binding domain with NAP1 and TANK.
#=GF RA   Ryzhakov G, Randow F;
#=GF RL   EMBO J. 2007;26:3180-3190.
#=GF DR   INTERPRO; IPR024581;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain
#=GF CC   able to bind kinases, has been found to be essential for
#=GF CC   poly(I:C)-induced IRF activation [1]. The domain is found in
#=GF CC   SINTBAD, TANK and NAP1 protein. This domain is predicted to form
#=GF CC   an a-helix with residues essential for kinase binding clustering
#=GF CC   on one side [1].
#=GF SQ   1453
#=GS A0A6P8VDJ8_GYMAC/107-162    AC A0A6P8VDJ8.1
#=GS M3ZC42_NOMLE/132-186        AC M3ZC42.2
#=GS A0A3Q2WFX4_HAPBU/292-360    AC A0A3Q2WFX4.1
#=GS A0A2K6UI22_SAIBB/190-235    AC A0A2K6UI22.1
#=GS A0A8C3YAB7_CATUS/84-136     AC A0A8C3YAB7.1
#=GS A0A2K6GND2_PROCO/288-342    AC A0A2K6GND2.1
#=GS A0A6P7YF28_9AMPH/211-266    AC A0A6P7YF28.1
#=GS Q08CI3_DANRE/126-180        AC Q08CI3.1
#=GS A0A7J5Y1X6_DISMA/107-164    AC A0A7J5Y1X6.1
#=GS A0A6P3IY61_BISBI/56-110     AC A0A6P3IY61.1
#=GS A0A7N4PAS4_SARHA/344-398    AC A0A7N4PAS4.1
#=GS A0A0D9RBD0_CHLSB/213-265    AC A0A0D9RBD0.1
#=GS A0A6J2Q763_COTGO/291-342    AC A0A6J2Q763.1
#=GS A0A811ZPX6_NYCPR/152-206    AC A0A811ZPX6.1
#=GS W5KL41_ASTMX/313-367        AC W5KL41.2
#=GS A0A8J6FYT8_MICOH/289-343    AC A0A8J6FYT8.1
#=GS A0A4W2EXC4_BOBOX/191-245    AC A0A4W2EXC4.1
#=GS A0A8B9RXK2_9AVES/216-271    AC A0A8B9RXK2.1
#=GS A0A2K5M3R7_CERAT/177-221    AC A0A2K5M3R7.1
#=GS A0A8C9KZE8_PANTA/132-186    AC A0A8C9KZE8.1
#=GS A0A8C1E9A1_CYPCA/14-67      AC A0A8C1E9A1.1
#=GS A0A1U7QC75_MESAU/368-422    AC A0A1U7QC75.1
#=GS A0A7K8PNT7_COCCO/222-272    AC A0A7K8PNT7.1
#=GS A0A2K5HPN6_COLAP/132-186    AC A0A2K5HPN6.1
#=GS A2AR78_MOUSE/130-184        AC A2AR78.1
#=GS A0A0Q3P8C6_AMAAE/1114-1168  AC A0A0Q3P8C6.1
#=GS A0A7L1KBE4_RYNNI/214-272    AC A0A7L1KBE4.1
#=GS A0A7K6JNP5_9PASE/212-262    AC A0A7K6JNP5.1
#=GS A0A1S3WC82_ERIEU/133-186    AC A0A1S3WC82.1
#=GS A0A7N4NSF4_SARHA/292-346    AC A0A7N4NSF4.1
#=GS A0A0A0ABU3_CHAVO/219-273    AC A0A0A0ABU3.1
#=GS A0A8I5UMJ9_PONAB/190-244    AC A0A8I5UMJ9.1
#=GS A0A667HMM6_LYNCA/151-205    AC A0A667HMM6.1
#=GS A0A670K9J9_PODMU/234-289    AC A0A670K9J9.1
#=GS A0A096P535_PAPAN/288-342    AC A0A096P535.2
#=GS A0A4W6FVH1_LATCA/303-358    AC A0A4W6FVH1.1
#=GS A0A8D2F0P6_THEGE/189-234    AC A0A8D2F0P6.1
#=GS A0A2U3YD96_LEPWE/214-266    AC A0A2U3YD96.1
#=GS A0A7K9P1E6_9CORV/225-292    AC A0A7K9P1E6.1
#=GS A0A7K6H2D8_9PASS/222-266    AC A0A7K6H2D8.1
#=GS A0A6P5DTE6_BOSIN/172-224    AC A0A6P5DTE6.1
#=GS A0A5N5PCA5_PANHP/166-222    AC A0A5N5PCA5.1
#=GS A0A091RS84_NESNO/216-270    AC A0A091RS84.1
#=GS A0A6F9BNZ0_9TELE/1-69       AC A0A6F9BNZ0.1
#=GS A0A7L4CJA2_9AVES/231-285    AC A0A7L4CJA2.1
#=GS A0A8P0NLW3_CANLF/132-186    AC A0A8P0NLW3.1
#=GS A0A7J7WJT4_MYOMY/132-186    AC A0A7J7WJT4.1
#=GS A0A6J0A2V5_ACIJB/132-186    AC A0A6J0A2V5.1
#=GS A0A6G1B352_CROCR/132-186    AC A0A6G1B352.1
#=GS A0A8C1E983_CYPCA/124-178    AC A0A8C1E983.1
#=GS A0A6I9NXW7_9TELE/107-162    AC A0A6I9NXW7.1
#=GS A0A8D0EF26_SALMN/195-250    AC A0A8D0EF26.1
#=GS A0A4X2M465_VOMUR/135-189    AC A0A4X2M465.1
#=GS H9GRY7_ANOCA/194-248        AC H9GRY7.2
#=GS A0A151LYD3_ALLMI/1-50       AC A0A151LYD3.1
#=GS A0A2U9CBA6_SCOMX/110-165    AC A0A2U9CBA6.1
#=GS A0A7J8FUD0_MOLMO/22-72      AC A0A7J8FUD0.1
#=GS A0A2K5PE36_CEBIM/132-186    AC A0A2K5PE36.1
#=GS A0A8B7VAZ9_CASCN/170-224    AC A0A8B7VAZ9.1
#=GS A0A8C6ZMH4_NOTPE/268-327    AC A0A8C6ZMH4.1
#=GS A0A8B9BI38_9AVES/234-289    AC A0A8B9BI38.1
#=GS A0A8C6IN65_MELUD/216-271    AC A0A8C6IN65.1
#=GS A0A851NWP8_9GALL/226-282    AC A0A851NWP8.1
#=GS A0A7J7EJE4_DICBM/288-342    AC A0A7J7EJE4.1
#=GS V9KT79_CALMI/222-276        AC V9KT79.1
#=GS A0A8C3CFN2_CAIMO/216-271    AC A0A8C3CFN2.1
#=GS A0A4W2BSP6_BOBOX/214-266    AC A0A4W2BSP6.1
#=GS A0A803V9G6_FICAL/216-271    AC A0A803V9G6.1
#=GS A0A8V5G2M7_MELUD/181-236    AC A0A8V5G2M7.1
#=GS A0A6P5DR76_BOSIN/214-266    AC A0A6P5DR76.1
#=GS A0A8C5J046_JUNHY/188-243    AC A0A8C5J046.1
#=GS A0A8D2KUC3_VARKO/218-274    AC A0A8D2KUC3.1
#=GS A0A3Q4I2M9_NEOBR/186-253    AC A0A3Q4I2M9.1
#=GS A0A5J5MKY1_MUNRE/71-123     AC A0A5J5MKY1.1
#=GS A0A8C7DWQ2_NAJNA/263-318    AC A0A8C7DWQ2.1
#=GS A0A8C5SMT7_LATLA/196-250    AC A0A8C5SMT7.1
#=GS A0A6I9P2T7_9TELE/107-164    AC A0A6I9P2T7.1
#=GS A0A6J2M2Z7_9CHIR/172-224    AC A0A6J2M2Z7.1
#=GS A0A8C8RH60_9SAUR/136-191    AC A0A8C8RH60.1
#=GS A0A7L1XX85_9AVES/230-285    AC A0A7L1XX85.1
#=GS H3C5J3_TETNG/122-175        AC H3C5J3.1
#=GS A0A8U0RMK0_MUSPF/286-340    AC A0A8U0RMK0.1
#=GS A0A3P9NR06_POERE/50-105     AC A0A3P9NR06.1
#=GS A0A670YW89_PSETE/210-260    AC A0A670YW89.1
#=GS A0A7L4AXH2_9CHAR/231-295    AC A0A7L4AXH2.1
#=GS A0A384DLQ7_URSMA/214-266    AC A0A384DLQ7.1
#=GS F7FH52_MONDO/214-266        AC F7FH52.2
#=GS G1KPN5_ANOCA/227-282        AC G1KPN5.2
#=GS A0A151M0A1_ALLMI/180-234    AC A0A151M0A1.1
#=GS A0A674HVM8_TERCA/214-268    AC A0A674HVM8.1
#=GS A0A5F9D0J6_RABIT/437-489    AC A0A5F9D0J6.1
#=GS A0A7L3W9S6_9GRUI/84-138     AC A0A7L3W9S6.1
#=GS H0XPA9_OTOGA/228-279        AC H0XPA9.1
#=GS A0A226NKB7_CALSU/217-265    AC A0A226NKB7.1
#=GS A0A7L0T0Z3_PODPO/226-294    AC A0A7L0T0Z3.1
#=GS A0A7J8FV24_MOLMO/132-186    AC A0A7J8FV24.1
#=GS A0A6P5CMY0_BOSIN/132-186    AC A0A6P5CMY0.1
#=GS A0A8C5WFX0_9ANUR/225-276    AC A0A8C5WFX0.1
#=GS A0A673VEG6_SURSU/132-186    AC A0A673VEG6.1
#=GS A0A3P8TS92_AMPPE/33-87      AC A0A3P8TS92.1
#=GS A0A7L1PQF4_ORIOR/225-284    AC A0A7L1PQF4.1
#=GS A0A2K6FAN9_PROCO/214-266    AC A0A2K6FAN9.1
#=GS A0A384A798_BALAS/133-187    AC A0A384A798.1
#=GS A0A7N9CYH7_MACFA/288-333    AC A0A7N9CYH7.1
#=GS A0A2K6G866_PROCO/132-186    AC A0A2K6G866.1
#=GS A0A6P6BZE2_PTEVA/288-342    AC A0A6P6BZE2.1
#=GS A0A8D0KY44_STROC/221-269    AC A0A8D0KY44.1
#=GS A0A6J0WBS2_ODOVR/288-335    AC A0A6J0WBS2.1
#=GS A0A7K9AL90_DRONO/190-245    AC A0A7K9AL90.1
#=GS A0A0G2K130_RAT/131-185      AC A0A0G2K130.1
#=GS A0A7J7XWF9_PIPKU/132-186    AC A0A7J7XWF9.1
#=GS A0A7M4E9K0_CROPO/218-273    AC A0A7M4E9K0.1
#=GS A0A8J6K2U6_ELECQ/186-243    AC A0A8J6K2U6.1
#=GS A0A8C1EHC0_CYPCA/124-179    AC A0A8C1EHC0.1
#=GS A0A5F9CB90_RABIT/132-186    AC A0A5F9CB90.1
#=GS A0A672VAM4_STRHB/189-244    AC A0A672VAM4.1
#=GS A0A7K9HMK0_9AVES/226-280    AC A0A7K9HMK0.1
#=GS A0A2K6QR61_RHIRO/288-342    AC A0A2K6QR61.1
#=GS A0A7K5VUF5_9CORV/226-279    AC A0A7K5VUF5.1
#=GS A0A8B7A1E8_ORYAF/131-185    AC A0A8B7A1E8.1
#=GS A0A6P3EXY7_OCTDE/214-266    AC A0A6P3EXY7.1
#=GS A0A6J3IK62_SAPAP/137-191    AC A0A6J3IK62.1
#=GS A0A7L1ZTM6_LEILU/222-276    AC A0A7L1ZTM6.1
#=GS A0A5N3Y0I9_MUNRE/214-266    AC A0A5N3Y0I9.1
#=GS A0A4Z2CFQ6_9TELE/109-164    AC A0A4Z2CFQ6.1
#=GS A0A8C8Z5S7_PROSS/288-333    AC A0A8C8Z5S7.1
#=GS A0A2K6GND5_PROCO/288-342    AC A0A2K6GND5.1
#=GS H2QDA4_PANTR/288-342        AC H2QDA4.2
#=GS A0A2K6UV72_SAIBB/213-265    AC A0A2K6UV72.1
#=GS A0A8W4F8D0_PIG/106-160      AC A0A8W4F8D0.1
#=GS A0A8D0LBP5_SPHPU/282-336    AC A0A8D0LBP5.1
#=GS A0A8C7HKJ3_ONCKI/129-184    AC A0A8C7HKJ3.1
#=GS TANK_HUMAN/132-186          AC Q92844.2
#=GS A0A2K5U1Z2_MACFA/189-234    AC A0A2K5U1Z2.1
#=GS A0A3Q7TLJ2_VULVU/214-266    AC A0A3Q7TLJ2.1
#=GS A0A669PQV6_PHACC/191-245    AC A0A669PQV6.1
#=GS A0A093IFZ6_DRYPU/216-270    AC A0A093IFZ6.1
#=GS A0A8C2VNT4_CHILA/298-350    AC A0A8C2VNT4.1
#=GS A0A6I9IXC2_CHRAS/289-343    AC A0A6I9IXC2.1
#=GS A0A4D9FAI8_9SAUR/196-251    AC A0A4D9FAI8.1
#=GS AZI2_HUMAN/213-265          AC Q9H6S1.1
#=GS A0A8C6FVC0_MOSMO/214-266    AC A0A8C6FVC0.1
#=GS F6WYF7_CALJA/213-265        AC F6WYF7.1
#=GS A0A7K5JI45_9TYRA/224-273    AC A0A7K5JI45.1
#=GS A0A8J7TJU5_ATRSP/209-263    AC A0A8J7TJU5.1
#=GS A0A663EY81_AQUCH/191-245    AC A0A663EY81.1
#=GS E7ENY2_HUMAN/133-187        AC E7ENY2.1
#=GS A0A7J8JNR9_ROUAE/1-33       AC A0A7J8JNR9.1
#=GS A0A8I5NQJ4_PAPAN/288-333    AC A0A8I5NQJ4.1
#=GS A0A8C6MWD0_MUSSI/130-184    AC A0A8C6MWD0.1
#=GS A0A452CDM3_BALAS/348-402    AC A0A452CDM3.1
#=GS A0A8C2W3B0_CHILA/199-253    AC A0A8C2W3B0.1
#=GS W5KT29_ASTMX/287-362        AC W5KT29.2
#=GS G1M155_AILME/132-186        AC G1M155.2
#=GS A0A1L8ES15_XENLA/277-334    AC A0A1L8ES15.1
#=GS A0A2K5DWA8_AOTNA/132-186    AC A0A2K5DWA8.1
#=GS A0A6G0HWC4_LARCR/316-360    AC A0A6G0HWC4.1
#=GS TBKB1_RAT/289-343           AC Q6DG50.1
#=GS A0A2K6LR54_RHIBE/132-186    AC A0A2K6LR54.1
#=GS A0A673CU49_9TELE/15-68      AC A0A673CU49.1
#=GS AZI2_MOUSE/226-278          AC Q9QYP6.1
#=GS A0A7N4NZQ7_SARHA/214-263    AC A0A7N4NZQ7.1
#=GS A0A7R5KC87_9PASS/153-208    AC A0A7R5KC87.1
#=GS A0A3P9PAZ0_POERE/355-409    AC A0A3P9PAZ0.1
#=GS A0A673Z7L8_SALTR/129-184    AC A0A673Z7L8.1
#=GS A0A5N4CYW6_CAMDR/225-272    AC A0A5N4CYW6.1
#=GS A0A8C5LBK2_JACJA/214-266    AC A0A8C5LBK2.1
#=GS A0A452EY02_CAPHI/227-279    AC A0A452EY02.1
#=GS A0A7J8GGM5_ROUAE/287-332    AC A0A7J8GGM5.1
#=GS A0A091UPB5_PHALP/216-270    AC A0A091UPB5.1
#=GS A0A7L0RJ49_GLABR/221-267    AC A0A7L0RJ49.1
#=GS A0A8C2TPQ5_COTJA/218-272    AC A0A8C2TPQ5.1
#=GS A0A6P5KZY6_PHACI/282-330    AC A0A6P5KZY6.1
#=GS A0A3P8W6M2_CYNSE/294-348    AC A0A3P8W6M2.1
#=GS A0A8C0D5Y6_BALMU/132-186    AC A0A8C0D5Y6.1
#=GS A0A6J1U489_9SAUR/281-341    AC A0A6J1U489.1
#=GS W5PEZ8_SHEEP/287-341        AC W5PEZ8.1
#=GS A0A673BJY3_9TELE/267-321    AC A0A673BJY3.1
#=GS A0A8B9VYK2_9AVES/190-245    AC A0A8B9VYK2.1
#=GS A0A096MYZ7_PAPAN/213-265    AC A0A096MYZ7.1
#=GS A0A8J0R510_XENTR/211-257    AC A0A8J0R510.1
#=GS A0A6F9CD72_9TELE/129-184    AC A0A6F9CD72.1
#=GS A0A8C5VLZ9_MICMU/189-233    AC A0A8C5VLZ9.1
#=GS A0A6J1UJ15_9SAUR/196-250    AC A0A6J1UJ15.1
#=GS A0A6P6QFI8_CARAU/285-360    AC A0A6P6QFI8.1
#=GS A0A1U7SZG6_CARSF/211-263    AC A0A1U7SZG6.1
#=GS A0A7L1RAM7_9PASS/224-282    AC A0A7L1RAM7.1
#=GS A0A8B7VD62_CASCN/94-148     AC A0A8B7VD62.1
#=GS A0A8C3D1I1_CAIMO/190-245    AC A0A8C3D1I1.1
#=GS A0A8C9D973_PANLE/132-186    AC A0A8C9D973.1
#=GS A0A8D2ND18_ZONAL/188-243    AC A0A8D2ND18.1
#=GS A0A7J7SV41_PIPKU/288-341    AC A0A7J7SV41.1
#=GS A0A444UC07_ACIRT/298-349    AC A0A444UC07.1
#=GS Z4YKN2_MOUSE/288-342        AC Z4YKN2.1
#=GS A0A8C8WQW9_PANLE/288-342    AC A0A8C8WQW9.1
#=GS A0A3Q4HCT5_NEOBR/29-83      AC A0A3Q4HCT5.1
#=GS K7G4G0_PELSI/79-128         AC K7G4G0.1
#=GS A0A8C8XSM9_PANLE/132-186    AC A0A8C8XSM9.1
#=GS A0A485PCF9_LYNPA/220-272    AC A0A485PCF9.1
#=GS A0A2K6R7T5_RHIRO/189-234    AC A0A2K6R7T5.1
#=GS A0A287D891_ICTTR/132-186    AC A0A287D891.1
#=GS A0A7K5MHX1_CARCD/225-282    AC A0A7K5MHX1.1
#=GS A0A667GGD3_LYNCA/178-232    AC A0A667GGD3.1
#=GS A0A8B9G885_9PSIT/236-291    AC A0A8B9G885.1
#=GS F7A092_MOUSE/153-197        AC F7A092.1
#=GS A0A094LBS9_PODCR/216-273    AC A0A094LBS9.1
#=GS A0A8J7T7S4_ATRSP/437-482    AC A0A8J7T7S4.1
#=GS A0A6J0UZB0_9SAUR/237-288    AC A0A6J0UZB0.1
#=GS A0A3Q1CKU3_AMPOC/240-308    AC A0A3Q1CKU3.1
#=GS M3WDK4_FELCA/317-371        AC M3WDK4.4
#=GS A0A2U4ABU1_TURTR/133-187    AC A0A2U4ABU1.1
#=GS A0A4X2M7F5_VOMUR/173-225    AC A0A4X2M7F5.1
#=GS A0A7L2FXH9_QUIME/81-136     AC A0A7L2FXH9.1
#=GS A0A5F8GRN4_MONDO/154-208    AC A0A5F8GRN4.1
#=GS A0A7L1QME9_9PASS/224-281    AC A0A7L1QME9.1
#=GS A0A2K5YA65_MANLE/213-265    AC A0A2K5YA65.1
#=GS A0A4W2EXE6_BOBOX/132-186    AC A0A4W2EXE6.1
#=GS M3XN89_MUSPF/152-206        AC M3XN89.1
#=GS A0A2P4T985_BAMTH/56-110     AC A0A2P4T985.1
#=GS A0A455AFJ0_PHYMC/133-187    AC A0A455AFJ0.1
#=GS A0A7J7WJG5_MYOMY/1-33       AC A0A7J7WJG5.1
#=GS A0A2Y9N8J0_DELLE/237-291    AC A0A2Y9N8J0.1
#=GS A0A484CIP1_PERFV/291-336    AC A0A484CIP1.1
#=GS A0A091IX61_EGRGA/216-270    AC A0A091IX61.1
#=GS W5PYW5_SHEEP/214-266        AC W5PYW5.1
#=GS A0A8D2Q9F7_ZONAL/216-271    AC A0A8D2Q9F7.1
#=GS A0A7L1FN58_SYLBO/222-279    AC A0A7L1FN58.1
#=GS A0A6J0E011_PERMB/118-172    AC A0A6J0E011.1
#=GS A0A091QZN0_LEPDC/232-286    AC A0A091QZN0.1
#=GS A0A7N4NUU4_SARHA/154-208    AC A0A7N4NUU4.1
#=GS A0A7K6V516_9PASS/225-292    AC A0A7K6V516.1
#=GS A0A2G9RBE7_LITCT/3-54       AC A0A2G9RBE7.1
#=GS A0A8C4B2B8_9TELE/209-266    AC A0A8C4B2B8.1
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#=GC seq_cons                          ..............pptslppsa.h-LKcEhpplphLochQs-hL+KLptt..ss..s..s...p.....c................p...........h.........s........h........PlpCh-............................................
//