#=GF ID TC1
#=GF AC PF15063.10
#=GF DE Thyroid cancer protein 1
#=GF AU Hetherington K;
#=GF SE Jackhmmer:Q9NR00
#=GF GA 27.00 27.00;
#=GF TC 27.10 30.80;
#=GF NC 21.80 18.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF WK C8orf4
#=GF RN [1]
#=GF RM 15087392
#=GF RT TC-1 is a novel tumorigenic and natively disordered protein
#=GF RT associated with thyroid cancer.
#=GF RA Sunde M, McGrath KC, Young L, Matthews JM, Chua EL, Mackay JP,
#=GF RA Death AK;
#=GF RL Cancer Res. 2004;64:2766-2773.
#=GF RN [2]
#=GF RM 18959821
#=GF RT TC1 (C8orf4) is involved in ERK1/2 pathway-regulated G(1)- to
#=GF RT S-phase transition.
#=GF RA Wang YD, Bian GH, Lv XY, Zheng R, Sun H, Zhang Z, Chen Y, Li QW,
#=GF RA Xiao Y, Yang QT, Ai JZ, Wei YQ, Zhou Q;
#=GF RL BMB Rep. 2008;41:733-738.
#=GF RN [3]
#=GF RM 17905836
#=GF RT The intrinsically disordered TC-1 interacts with Chibby via
#=GF RT regions with high helical propensity.
#=GF RA Gall C, Xu H, Brickenden A, Ai X, Choy WY;
#=GF RL Protein Sci. 2007;16:2510-2518.
#=GF DR INTERPRO; IPR020282;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Thyroid cancer protein 1 (TC1) is thought to decrease in
#=GF CC apoptosis and increase cell proliferation. It is found to be
#=GF CC expressed in thyroid papillary carcinoma [1]. This suggests its
#=GF CC importance in thyroid cancer. The molecular mechanism of TC1,
#=GF CC involves up-regulating cell signalling through ERK-1/2
#=GF CC signalling pathway and it positively regulates transition
#=GF CC between the G1 and S phase in the cell cycle [2]. It is thought
#=GF CC to positively regulate Wnt/beta-catenin signalling pathway by
#=GF CC interacting with its repressor [3]. In humans, it is located in
#=GF CC the chromosomal position, C8orf4. This family of proteins is
#=GF CC found in eukaryotes and contains a conserved NIF sequence motif.
#=GF SQ 1069
#=GS W5PNG1_SHEEP/1-75 AC W5PNG1.1
#=GS A0A1S3FAT3_DIPOR/1-75 AC A0A1S3FAT3.1
#=GS A0A7K5B2R3_9FURN/1-74 AC A0A7K5B2R3.1
#=GS A0A2Y9FMX0_PHYMC/1-75 AC A0A2Y9FMX0.1
#=GS A0A8V5FHC1_MELUD/1-74 AC A0A8V5FHC1.1
#=GS A0A852DB56_PASAF/1-74 AC A0A852DB56.1
#=GS A0A7L1MYH3_RHICY/1-74 AC A0A7L1MYH3.1
#=GS A0A6P5BG69_BOSIN/1-75 AC A0A6P5BG69.1
#=GS A0A7K6UU93_9PASS/1-75 AC A0A7K6UU93.1
#=GS A0A7K8FT50_9CORV/10-85 AC A0A7K8FT50.1
#=GS A0A7L1WNF6_9PASS/1-57 AC A0A7L1WNF6.1
#=GS A0A667GBD1_LYNCA/11-86 AC A0A667GBD1.1
#=GS B5X7Y9_SALSA/5-80 AC B5X7Y9.1
#=GS A0A8C9XQL2_SANLU/4-79 AC A0A8C9XQL2.1
#=GS A0A7K5A5B6_9AVES/10-85 AC A0A7K5A5B6.1
#=GS H3C5E7_TETNG/11-86 AC H3C5E7.1
#=GS A0A7L4JGQ0_9PASS/1-74 AC A0A7L4JGQ0.1
#=GS A0A3P9MTH2_POERE/1-83 AC A0A3P9MTH2.1
#=GS A0A096P620_PAPAN/1-75 AC A0A096P620.1
#=GS A0A7K6LV95_9CORV/10-85 AC A0A7K6LV95.1
#=GS A0A094L7D7_PODCR/10-85 AC A0A094L7D7.1
#=GS A0A7K9U365_9AVES/10-85 AC A0A7K9U365.1
#=GS A0A662YYL3_ACIRT/45-120 AC A0A662YYL3.1
#=GS A0A2U4BQ21_TURTR/8-82 AC A0A2U4BQ21.1
#=GS A0A674I5W5_TERCA/10-85 AC A0A674I5W5.1
#=GS L9L952_TUPCH/10-85 AC L9L952.1
#=GS A0A3M0KKM4_HIRRU/1-74 AC A0A3M0KKM4.1
#=GS A0A5E4AMR7_MARMO/1-75 AC A0A5E4AMR7.1
#=GS U3KIM3_FICAL/9-84 AC U3KIM3.1
#=GS A0A851ASN4_PICGY/1-76 AC A0A851ASN4.1
#=GS A0A6F9BRG1_9TELE/27-103 AC A0A6F9BRG1.1
#=GS A0A8C5S9G0_LATLA/21-94 AC A0A8C5S9G0.1
#=GS A0A4Z2BF15_9TELE/4-79 AC A0A4Z2BF15.1
#=GS G1Q4T2_MYOLU/1-75 AC G1Q4T2.1
#=GS A0A3Q3XRI4_MOLML/5-89 AC A0A3Q3XRI4.1
#=GS A0A7L4MHJ8_GLAPT/10-85 AC A0A7L4MHJ8.1
#=GS A0A7K6E8T4_9PASS/10-85 AC A0A7K6E8T4.1
#=GS A0A7L2ZRP5_9PASE/10-85 AC A0A7L2ZRP5.1
#=GS A0A7L1U9R3_PHANI/10-85 AC A0A7L1U9R3.1
#=GS L5LTP6_MYODS/10-85 AC L5LTP6.1
#=GS A0A2K6V945_SAIBB/10-85 AC A0A2K6V945.1
#=GS A0A484CH87_PERFV/15-89 AC A0A484CH87.1
#=GS A0A8C6HRL0_MUSSI/10-85 AC A0A8C6HRL0.1
#=GS A0A643BZL8_BALPH/1-74 AC A0A643BZL8.1
#=GS A0A452I1H0_9SAUR/10-85 AC A0A452I1H0.1
#=GS A0A851KLD4_VIDCH/10-85 AC A0A851KLD4.1
#=GS A0A8C5I0I2_9TELE/21-95 AC A0A8C5I0I2.1
#=GS A0A1L8GRS5_XENLA/1-74 AC A0A1L8GRS5.1
#=GS A0A673SUE1_SURSU/1-74 AC A0A673SUE1.1
#=GS A0A2Y9J8B1_ENHLU/70-144 AC A0A2Y9J8B1.1
#=GS A0A852EIQ6_VIDMA/10-85 AC A0A852EIQ6.1
#=GS A0A8C8WH16_PANLE/11-86 AC A0A8C8WH16.1
#=GS A0A7K5YCJ3_9AVES/10-85 AC A0A7K5YCJ3.1
#=GS A0A6J2G286_9PASS/10-85 AC A0A6J2G286.1
#=GS A0A672R3Q6_SINGR/5-82 AC A0A672R3Q6.1
#=GS A0A852A312_CALOR/10-85 AC A0A852A312.1
#=GS A0A8C3UP70_CATUS/10-81 AC A0A8C3UP70.1
#=GS A0A1U7Q4L7_MESAU/1-75 AC A0A1U7Q4L7.1
#=GS A0A6P8SYF2_GYMAC/4-79 AC A0A6P8SYF2.1
#=GS A0A6P7Y1Q2_9AMPH/28-102 AC A0A6P7Y1Q2.1
#=GS A0A8B7RUN2_HIPAR/10-85 AC A0A8B7RUN2.1
#=GS A0A8C2XJ18_CYCLU/3-79 AC A0A8C2XJ18.1
#=GS A0A7K5XAS9_9CHAR/10-85 AC A0A7K5XAS9.1
#=GS A0A2K6KFZ0_RHIBE/1-75 AC A0A2K6KFZ0.1
#=GS A0A8C9E9Y2_PHOSS/1-75 AC A0A8C9E9Y2.1
#=GS A0A3Q4MNH7_NEOBR/4-79 AC A0A3Q4MNH7.1
#=GS A0A7L3JTP7_THACH/10-85 AC A0A7L3JTP7.1
#=GS A0A8C6EC12_MOSMO/1-75 AC A0A8C6EC12.1
#=GS A0A226N656_CALSU/1-74 AC A0A226N656.1
#=GS A0A3Q1IKQ6_ANATE/4-79 AC A0A3Q1IKQ6.1
#=GS W5M7S4_LEPOC/5-79 AC W5M7S4.1
#=GS L9JFF9_TUPCH/10-84 AC L9JFF9.1
#=GS A0A8D2F2C6_THEGE/10-85 AC A0A8D2F2C6.1
#=GS A0A437D287_ORYJA/4-79 AC A0A437D287.1
#=GS A0A091DWB8_FUKDA/9-84 AC A0A091DWB8.1
#=GS D2H9Q3_AILME/10-85 AC D2H9Q3.1
#=GS A0A4Z2IE32_9TELE/15-89 AC A0A4Z2IE32.1
#=GS A0A7L1CL11_9PASS/10-85 AC A0A7L1CL11.1
#=GS A0A7K7INQ5_LOXCU/10-85 AC A0A7K7INQ5.1
#=GS R0L280_ANAPL/10-85 AC R0L280.1
#=GS A0A7L4DED0_9AVES/10-85 AC A0A7L4DED0.1
#=GS A0A8W4FDG5_PIG/1-75 AC A0A8W4FDG5.1
#=GS A0A8C7FK40_ONCKI/5-80 AC A0A8C7FK40.1
#=GS A0A315V0S5_GAMAF/6-74 AC A0A315V0S5.1
#=GS A0A8B9BCK7_9AVES/10-85 AC A0A8B9BCK7.1
#=GS A0A8B9MPL2_9AVES/1-74 AC A0A8B9MPL2.1
#=GS A0A7N4NHR5_SARHA/1-74 AC A0A7N4NHR5.1
#=GS A0A7K4U9B4_9SYLV/1-74 AC A0A7K4U9B4.1
#=GS A0A7K5VBH3_9CORV/1-70 AC A0A7K5VBH3.1
#=GS A0A6G0JAV3_LARCR/3-93 AC A0A6G0JAV3.1
#=GS A0A7L3E593_9PASS/1-74 AC A0A7L3E593.1
#=GS A0A7K5U6W1_CEPOR/10-85 AC A0A7K5U6W1.1
#=GS A0A3P8T831_AMPPE/16-83 AC A0A3P8T831.1
#=GS A0A7K9KVA3_9PASS/1-57 AC A0A7K9KVA3.1
#=GS A0A6F8ZNR2_9TELE/6-81 AC A0A6F8ZNR2.1
#=GS A0A3P8W4K2_CYNSE/4-79 AC A0A3P8W4K2.1
#=GS A0A851W354_CORMO/1-74 AC A0A851W354.1
#=GS A0A8C4REG1_ERPCA/2-70 AC A0A8C4REG1.1
#=GS A0A7K9ZYE5_9CORV/1-55 AC A0A7K9ZYE5.1
#=GS A0A7L3ZQQ3_9AVES/10-85 AC A0A7L3ZQQ3.1
#=GS H2QW26_PANTR/10-85 AC H2QW26.1
#=GS A0A7L1LA72_HIMHI/10-85 AC A0A7L1LA72.1
#=GS A0A0A0A122_CHAVO/10-85 AC A0A0A0A122.1
#=GS A0A7K7Q0E7_ACRAR/1-74 AC A0A7K7Q0E7.1
#=GS A0A7E6DUV8_9CHIR/56-130 AC A0A7E6DUV8.1
#=GS A0A7K6M6A9_PANBI/1-74 AC A0A7K6M6A9.1
#=GS A0A3Q3WVS9_MOLML/4-79 AC A0A3Q3WVS9.1
#=GS A0A7L1J291_SMUAF/10-85 AC A0A7L1J291.1
#=GS A0A3Q2ZS57_KRYMA/3-75 AC A0A3Q2ZS57.1
#=GS A0A852CUF4_9PICI/1-74 AC A0A852CUF4.1
#=GS A0A8C5UAW3_9PASS/10-85 AC A0A8C5UAW3.1
#=GS A0A8D2LGV9_VARKO/55-128 AC A0A8D2LGV9.1
#=GS A0A1S3W301_ERIEU/10-85 AC A0A1S3W301.1
#=GS A0A3Q1H393_ANATE/5-73 AC A0A3Q1H393.2
#=GS A0A2Y9MR82_DELLE/8-82 AC A0A2Y9MR82.1
#=GS A0A6P6KT83_CARAU/4-79 AC A0A6P6KT83.1
#=GS A0A7K9PML7_9CORV/10-85 AC A0A7K9PML7.1
#=GS A0A6P6L747_CARAU/4-75 AC A0A6P6L747.1
#=GS A0A6P8R058_GEOSA/10-85 AC A0A6P8R058.1
#=GS F7CNT6_MONDO/1-75 AC F7CNT6.1
#=GS A0A7K5IYG7_TOXRE/10-85 AC A0A7K5IYG7.1
#=GS A0A7L1W215_9PASS/10-85 AC A0A7L1W215.1
#=GS A0A7K8E0V7_LEURO/10-85 AC A0A7K8E0V7.1
#=GS A0A7K7BM83_APHCE/1-74 AC A0A7K7BM83.1
#=GS A0A671QDY9_9TELE/4-79 AC A0A671QDY9.1
#=GS A0A7L2IJS7_9PICI/1-74 AC A0A7L2IJS7.1
#=GS A0A2K5JIL8_COLAP/10-85 AC A0A2K5JIL8.1
#=GS A0A8C1GDB5_CYPCA/12-86 AC A0A8C1GDB5.1
#=GS A0A1S3T0N9_SALSA/29-113 AC A0A1S3T0N9.1
#=GS A0A6P9DTE5_PANGU/1-74 AC A0A6P9DTE5.1
#=GS A0A673GAT1_9TELE/4-84 AC A0A673GAT1.1
#=GS A0A7L3DB80_PLUSO/10-85 AC A0A7L3DB80.1
#=GS A0A7K7SQI2_9TYRA/10-85 AC A0A7K7SQI2.1
#=GS A0A674HZK8_TERCA/1-74 AC A0A674HZK8.1
#=GS A0A852HR15_9PASS/10-85 AC A0A852HR15.1
#=GS A0A091KFU6_9GRUI/10-85 AC A0A091KFU6.1
#=GS A0A7K6PEI4_9CORV/10-85 AC A0A7K6PEI4.1
#=GS A0A2Y9JDS7_ENHLU/54-128 AC A0A2Y9JDS7.1
#=GS M3Z017_MUSPF/1-75 AC M3Z017.1
#=GS A0A8C5XKL5_MICMU/1-75 AC A0A8C5XKL5.1
#=GS A0A8C4ULR3_FALTI/10-85 AC A0A8C4ULR3.1
#=GS A0A850YIZ9_AEGCA/10-85 AC A0A850YIZ9.1
#=GS A0A444UZB8_ACIRT/3-79 AC A0A444UZB8.1
#=GS A0A151MYX8_ALLMI/8-83 AC A0A151MYX8.1
#=GS A0A8C3CNU0_CAIMO/1-74 AC A0A8C3CNU0.1
#=GS W5LSN6_ASTMX/7-82 AC W5LSN6.2
#=GS A0A7K5GLM6_9AVES/10-85 AC A0A7K5GLM6.1
#=GS A0A8J0QSE6_XENTR/118-192 AC A0A8J0QSE6.1
#=GS A0A7L1XZ23_9AVES/10-85 AC A0A7L1XZ23.1
#=GS G1STV6_RABIT/1-75 AC G1STV6.1
#=GS A0A091S063_NESNO/10-85 AC A0A091S063.1
#=GS A0A2K5DTJ4_AOTNA/1-75 AC A0A2K5DTJ4.1
#=GS A0A8D2LL90_VARKO/12-87 AC A0A8D2LL90.1
#=GS S9WXY7_CAMFR/147-221 AC S9WXY7.1
#=GS A0A7L3VG83_MOLAT/10-85 AC A0A7L3VG83.1
#=GS A0A286ZYA1_PIG/1-75 AC A0A286ZYA1.1
#=GS A0A340XAT9_LIPVE/1-75 AC A0A340XAT9.1
#=GS A0A8C0R3I0_CANLU/1-75 AC A0A8C0R3I0.1
#=GS A0A091FPM3_9AVES/10-85 AC A0A091FPM3.1
#=GS H9GF98_ANOCA/7-82 AC H9GF98.2
#=GS A0A3Q2C773_CYPVA/4-79 AC A0A3Q2C773.1
#=GS A0A8C8J6B0_ONCTS/5-80 AC A0A8C8J6B0.1
#=GS A0A7K6HJY1_9PASS/1-74 AC A0A7K6HJY1.1
#=GS A0A1S3AQ56_ERIEU/1-75 AC A0A1S3AQ56.1
#=GS A0A6I8P4F5_ORNAN/21-95 AC A0A6I8P4F5.1
#=GS A0A7L3HTT2_9PASS/1-74 AC A0A7L3HTT2.1
#=GS A0A6P6ELZ4_OCTDE/29-104 AC A0A6P6ELZ4.1
#=GS A0A4W4EKX2_ELEEL/27-91 AC A0A4W4EKX2.1
#=GS A0A8J0TE17_XENLA/54-128 AC A0A8J0TE17.1
#=GS A0A8C5Q8N3_9ANUR/51-125 AC A0A8C5Q8N3.1
#=GS A0A8B7QWF3_HIPAR/1-75 AC A0A8B7QWF3.1
#=GS A0A8B9S141_9AVES/10-85 AC A0A8B9S141.1
#=GS A0A7K4VSC5_9EMBE/1-74 AC A0A7K4VSC5.1
#=GS A0A8M1PSN2_DANRE/4-76 AC A0A8M1PSN2.1
#=GS A0A7K6QSL6_9PASS/10-85 AC A0A7K6QSL6.1
#=GS A0A852FV13_PEUTA/10-85 AC A0A852FV13.1
#=GS A0A2K6K875_RHIBE/10-85 AC A0A2K6K875.1
#=GS A0A8B9XD28_BOSMU/10-85 AC A0A8B9XD28.1
#=GS A0A484DL40_PERFV/4-77 AC A0A484DL40.1
#=GS A0A8C2ULS1_CHILA/1-75 AC A0A8C2ULS1.1
#=GS A0A0P7VZD5_SCLFO/20-93 AC A0A0P7VZD5.1
#=GS A0A7K6KMC9_9PASE/1-74 AC A0A7K6KMC9.1
#=GS A0A7L4H460_PODST/10-85 AC A0A7L4H460.1
#=GS A0A850XPD0_PIACA/1-74 AC A0A850XPD0.1
#=GS A0A7J7E6F7_DICBM/1-75 AC A0A7J7E6F7.1
#=GS A0A3Q1GA56_9TELE/5-80 AC A0A3Q1GA56.1
#=GS A0A7K8S0J7_9PASS/1-74 AC A0A7K8S0J7.1
#=GS A0A553MWV8_9TELE/1-75 AC A0A553MWV8.1
#=GS A0A226P5E6_COLVI/1-74 AC A0A226P5E6.1
#=GS E0CXY9_MOUSE/1-76 AC E0CXY9.1
#=GS A0A8D0KNL6_SALMN/1-74 AC A0A8D0KNL6.1
#=GS H2NB76_PONAB/1-75 AC H2NB76.1
#=GS A0A7J7Z9P1_MYOMY/10-85 AC A0A7J7Z9P1.1
#=GS A0A851M7S8_CORCR/1-74 AC A0A851M7S8.1
#=GS A0A3Q7PRD5_CALUR/1-75 AC A0A3Q7PRD5.1
#=GS A0A7L0T4U6_PODPO/10-85 AC A0A7L0T4U6.1
#=GS A0A091QFD6_MERNU/10-85 AC A0A091QFD6.1
#=GS A0A7L2NER1_9PASS/10-85 AC A0A7L2NER1.1
#=GS A0A7K6KCR0_9PASE/10-85 AC A0A7K6KCR0.1
#=GS A0A7K7EHU6_9SYLV/1-74 AC A0A7K7EHU6.1
#=GS A0A7K8HAR9_9CORV/10-85 AC A0A7K8HAR9.1
#=GS A0A7L1EFG3_OENON/1-74 AC A0A7L1EFG3.1
#=GS A0A1A8UB14_NOTFU/4-79 AC A0A1A8UB14.1
#=GS A0A670JZL0_PODMU/10-85 AC A0A670JZL0.1
#=GS A0A7K8HRP0_9CORV/1-74 AC A0A7K8HRP0.1
#=GS A0A851S011_CERFA/10-85 AC A0A851S011.1
#=GS A0A4Z2HUD6_9TELE/4-94 AC A0A4Z2HUD6.1
#=GS A0A2U3UYH9_TURTR/10-85 AC A0A2U3UYH9.1
#=GS A0A5A9P6C4_9TELE/5-79 AC A0A5A9P6C4.1
#=GS A0A7L2DF22_CATFU/1-74 AC A0A7L2DF22.1
#=GS A0A643CI85_BALPH/2-44 AC A0A643CI85.1
#=GS A0A7K4PP82_MELMO/10-85 AC A0A7K4PP82.1
#=GS A0A4W4ELH9_ELEEL/26-73 AC A0A4W4ELH9.1
#=GS A0A8C5PEE9_9ANUR/9-84 AC A0A8C5PEE9.1
#=GS A0A8C6VLJ7_NAJNA/17-90 AC A0A8C6VLJ7.1
#=GS G5AYK7_HETGA/9-84 AC G5AYK7.1
#=GS A0A3Q2XI80_HAPBU/7-79 AC A0A3Q2XI80.1
#=GS A0A7K7DGN1_PHEME/1-74 AC A0A7K7DGN1.1
#=GS A0A7K6SUI6_CALNI/1-74 AC A0A7K6SUI6.1
#=GS A0A8C9P199_SPEDA/10-85 AC A0A8C9P199.1
#=GS A0A8C3FB15_CHRPI/10-85 AC A0A8C3FB15.1
#=GS A0A7L2B7P6_9GRUI/10-85 AC A0A7L2B7P6.1
#=GS A0A674H5G4_TAEGU/1-74 AC A0A674H5G4.1
#=GS A0A0Q3MIM7_AMAAE/10-85 AC A0A0Q3MIM7.1
#=GS A0A6I9YD07_9SAUR/1-74 AC A0A6I9YD07.1
#=GS A0A8C9CB57_PHOSS/10-85 AC A0A8C9CB57.1
#=GS A0A7L2I560_SAGSE/10-85 AC A0A7L2I560.1
#=GS A0A4Z2C6Y3_9TELE/17-91 AC A0A4Z2C6Y3.1
#=GS A0A6J0W3Q1_ODOVR/10-85 AC A0A6J0W3Q1.1
#=GS A0A851UIM6_9PASS/10-85 AC A0A851UIM6.1
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A0A8B6ZC24_ORYAF/10-85 ................ii--MSMSLRVSPS.V..H..G....Y....HF....D.T.......AARKKAVGNIFE........NIDQE..SLQR.LFKNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
A0A8J6ASA0_GALPY/1-75 ..................MGTPASVVSEPP.P..W..K....A....PT....E.A.......RGRKKASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALRKLR.................................
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A0A669Q0L1_PHACC/1-74 ..................MGTPASVASDPP.G..R..A....A....PA....-.A.......RGRKRASANIFQ........GVGLP..ELRS.LFQSGG....A..E...S..P....E...E..RA.RLVW...............RYAGQR.RMARVLRQLR.................................
A0A8B7QTH9_HIPAR/1-75 ..................MGTPASVVSEPP.P..W..Q....A....PT....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALRRLR.................................
A0A2K5HN68_COLAP/1-75 ..................MGTPASVVSEPP.P..W..Q....A....PT....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALKRLR.................................
A0A6I9LR13_PERMB/10-85 .................t-SMSSSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NVDQQ..SLQR.LFRNSG....D..K...K..A....E...E..RA.KIIL..............aIDQDLE.EKTRALMALK.................................
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A0A091U0K2_PHORB/8-83 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SVNEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
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A0A6J2QGB8_COTGO/4-79 ..................YASSECRRVSPS.V..H..G....N....KF....D.T.......AHRKKAAANIFD........NVNQD..ALMR.LFQKTG....D..M...K..A....E...E..RV.RSIF..............sYTQDPE.ETARALMALK.................................
A0A852ART0_9CORV/10-85 ..................AAMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAAANIFE........SINEA..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDME.EKTRALMALK.................................
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A0A2I0LLW2_COLLI/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SINQE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
A0A7L0F3E1_CORCN/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SINEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
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A0A668SQ29_OREAU/4-79 ................yv--SSECRRVSPS.V..H..G....N....KF....D.T.......AHRKKAVANIFE........NVNQD..ALMR.LFQKTG....D..M...K..A....E...E..RV.RSIF..............sYTQDPE.ETARALMALK.................................
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A0A672UEW3_STRHB/10-85 ..................AAMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKATANIFE........SINQE..SLQK.LFRNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
A0A7N5KSK6_AILME/1-75 ..................MGTPASVVSELP.P..W..Q....A....PA....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIVW...............ECAGDH.RVAEALRRLR.................................
A0A6P3QXZ0_PTEVA/1-75 ..................MGTPASVVSEPP.P..W..Q....A....PT....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.HVAEALRRLR.................................
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A0A8C6RNR2_NANGA/1-75 ..................MGTPASVVSEPP.L..W..Q....V....PA....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALRRLR.................................
A0A8C4PLY5_EQUAS/10-85 .................v-TMSTSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NIDQE..SLQR.LFKNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
A0A091IDM6_CALAN/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVPNIFE........SINEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
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A0A8C7I6L1_ONCKI/4-71 ...............peh----PSVEEGPS.L..L..W....Q....PE....K.R.......RSRKSGCSNIFA........GVNLR..QLRR.LFHVAG....D..R...D..A....E...Q..RA.RLVW...............GREERN.----------rgre.............................
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A0A7L0UXJ0_9PASE/10-85 ..................AAMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAAANIFE........SINEA..ALQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDME.EKTRALMALK.................................
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L5KE03_PTEAL/11-86 ................vv--MSTSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NIDQE..SLQR.LFKNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
A0A851XF44_EOLRO/10-85 ..................AAMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAAANIFE........SVNQE..SLQK.LFRNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
A0A7L4NMQ7_9AVES/10-85 ..................AAMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAAANIFE........SVNQE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
A0A4W6C4Z1_LATCA/22-95 ................st-SPPSRIVAGPS.S..-..-....R....LA....E.R.......RSRKAGSGNIFS........NVNLW..QLQR.LFRAAG....D..Q...D..A....E...Q..RA.QLIW...............GHGDET.ELAQALIGLR.................................
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A0A8B9UNW8_9AVES/10-85 .................s-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SIDEE..SLQK.LFKHSG....D..K...K..A....E...E..RA.KIIL..............aTDQDVE.EKTRALMALK.................................
A0A8P4GP06_DICLA/106-181 ................yv--SSESRRVSPT.V..H..G....N....KF....D.T.......AHRKKAVANIFE........NVNQD..SLMR.LFQKTG....D..M...K..A....E...E..RV.RSIF..............sYTQDPE.ETARALMALK.................................
A0A7L3V695_MOLAT/1-74 .................m-GTPASVVSDSP.G..R..A....A....PA....-.A.......RARKRASANIFQ........GVGLR..ELRS.LFRSGG....A..E...R..P....E...E..RA.RLVW...............RYAGQR.RMARALRRLR.................................
TCIM_BOVIN/10-85 .................f-SMSTSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NIDQE..ALQR.LFRNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
W5P249_SHEEP/29-104 .................f-SMSTSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NIDQE..ALQR.LFKNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
A0A096LPT4_POEFO/6-74 .....pakksfcrvsfnc------------.-..-..-....-....--....-.R.......RSRKSGCSNIFS........GVNLH..QLHR.LFRTAG....D..R...N..A....E...H..RA.KLVW...............QDMEANpEGAEA-----gkrs.............................
G3HGG0_CRIGR/10-85 .................t-SMSSSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NIDQQ..SLQR.LFRNSG....D..K...K..A....E...E..RA.KIIL..............aIDQDLE.EKTRALMALK.................................
F6T4H5_MONDO/1-75 .................l-GTPASVVSEPP.P..G..E....A....PV....E.V.......RRRKQASANIFQ........DAELL..QIQA.LFQRSG....D..R...Q..A....E...E..QA.QIIW...............ECAGDH.RVAEALRQLR.................................
A0A850WUY5_PIACA/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SVNEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............dTDQDLE.EKTRALMALK.................................
A0A7L4GU01_PODST/1-74 ..................MGTPASVVSDPP.G..R..A....A....PA....-.T.......RGRKRASANIFQ........GVGLP..ELRS.LFRSGG....A..E...R..P....E...E..RA.CLVW...............RYAGQR.RMARALRRLR.................................
A0A7K5LM53_VIRAL/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAAANIFE........SLNEE..SLQK.LFRNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDME.EKTRALMALK.................................
A0A668RMM0_OREAU/6-80 ..................ASPSSSMLAGRS.T..L..W....R....LS....E.R.......RSRKAGSANIFS........NVNLW..QLQR.LFRAAG....D..Q...D..A....E...Q..RA.QLIW...............GHGDEA.ELAKALIGLR.................................
A0A5N5JXB0_PANHP/7-81 ..saaavlpgapqptfcr------------.-..-..T....S....AS....E.R.......RMRKSGSANIFQ........GVNLR..QLRR.LFHSAG....E..P...D..A....E...Q..KA.RQVW...............RNRRRA.----------egdeedgd.........................
A0A850ZP37_9PASS/1-74 ..................MGTPASVVSDSP.A..R..A....A....PA....-.A.......RARKRASANIFQ........GVGLR..ELRS.LFRSGG....A..E...R..P....E...E..RA.CLVW...............RYAGQR.RMARALRRLR.................................
A0A7L3KFP0_9PASS/10-85 ..................AAMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAAANIFE........SINEA..SLQR.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDME.EKTRALMALK.................................
A0A8C1WXT5_CYPCA/4-79 ...............nmy---SESRRVCPS.I..H..G....N....KF....D.T.......ANRKRAVANIFE........NVNQD..ALMR.LFQKTG....D..M...K..A....E...E..RV.RSIF..............sFAHDPE.ETAKALMSLK.................................
A0A7N4PHR5_SARHA/1-75 ..................MGTPASVVSEPP.P..G..Q....A....PT....G.T.......RGRKQASANIFQ........DAELL..QIRG.LFQHSG....D..R...Q..A....E...E..RA.QIIW...............ECAGDP.KVAEALRQLR.................................
L5JND0_PTEAL/1-75 ..................MGTPASVVSEPP.P..W..Q....A....PT....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQHSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.HVAEALRRLR.................................
A0A7K8LWG6_9CORV/1-74 .................m-GTPASVASDSP.G..R..A....A....P-....A.A.......RARKRASANIFQ........GVGLL..ELRS.LFRSGG....A..E...R..P....E...E..RA.RLVW...............RYAGQR.RMARALRRLR.................................
A0A671W586_SPAAU/4-79 ................yv--SSECRRVSPS.V..H..G....N....KF....D.T.......AHRKKASANIFE........NVNQD..ALMR.LFQKTG....D..M...K..A....E...E..RV.RSIF..............sYTQDPE.ETARALMALK.................................
A0A8C6CVB0_MOSMO/10-85 .................f-SMSTSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVGNIFE........NIDQE..ALQR.LFKNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
A0A7L2M3H3_9SYLV/1-75 ..................MGTPASVVSDSP.G..R..A....A....PA....G.R.......-ARKRASANIFQ........GVGLR..ELRSlLFRGGG....A..E...R..P....E...E..RA.CLVW...............RYAGQR.RMARALRRLR.................................
A0A7R5KHF8_9PASS/1-74 ..................MGTPASVASDPP.G..R..A....A....PA....-.A.......RGRKRASANIFQ........GVGLL..ELRS.LFQSGG....A..E...R..P....E...E..RA.RLVW...............RYAGQR.RMARALRRLR.................................
A0A7K9WBS8_9PASS/1-74 .................m-GTPASVVSD-S.T..G..R....T....VP....A.A.......RARKRASANIFQ........GVGLL..ELRS.LFRSGG....A..E...R..P....E...E..RA.RLVW...............RYAGQR.RMARALRRLR.................................
A0A663DMQ2_AQUCH/1-74 ..................MGTPASVVSDPP.G..R..A....V....PA....-.A.......RGRKRASANIFQ........GVGLP..ELRS.LFRSGG....A..E...R..P....E...E..RA.RLVW...............RYAGQR.RMARALRRLR.................................
A0A0P7WFR3_SCLFO/4-79 ................yv--SSDCRRVSPS.S..H..G....T....RF....D.T.......ANRKKAAANIFE........NVNQD..ALMR.LFQKTG....D..M...K..A....E...E..RV.RSIF..............sYAHDPE.ETSKALMALK.................................
A0A8J6FCZ9_ELECQ/1-75 ..................MGTPASVISSPA.A..A..W....K....AP....E.P.......RTRKKASANIFK........DIDLL..QIQT.LFRTCG....D..E...C..A....D...E..RA.QIIY...............NYAGDK.SIAEALIKLR.................................
A0A093FCN9_GAVST/10-79 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SINEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKT-------r................................
A0A8C7X5B7_9TELE/31-92 ..........dysnnsly------------.-..-..-....-....--....-.-.......-IRKAGSGNIFS........NVNLW..QLQR.LFRAAG....D..H...D..A....E...Q..RA.KLVW...............GLGDEP.DLAQALIGLR.................................
A0A7K8XQI1_9PICI/10-85 .................p-AMSSSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SINEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
A0A7L1FSQ3_SYLBO/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SINEA..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDME.EKTRALMALK.................................
A0A7J7TSH9_MYOMY/1-75 ..................MGTPASVVSEPL.P..W..Q....A....PT....E.A.......RGRKQASANIFQ........DAELL..QIQS.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALRRLR.................................
H0Z407_TAEGU/10-85 .................p-AMSTSLRVSPS.V..H..G....C....RF....D.T.......ALRKKAAANIFE........SINEA..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDME.EKTRALMALK.................................
A0A3Q1G7M2_9TELE/10-84 ......mcstfstedgqt------------.A..Q..W....K....FS....S.P.......RSRKSGCSNIFT........GVNLH..QLQR.LFRTAG....D..R...N..A....E...H..RE.ESGM...............EREDEA.GLAQALVGLR.................................
A0A7K4SX52_9CHAR/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SVNEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
A0A8C9KQA4_PANTA/1-75 ..................MGTPASVVSEPP.P..W..Q....A....PA....E.A.......RGRKQATANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALRRLR.................................
U6CTB9_NEOVI/9-84 ................ai--MSTSLRVSPS.I..H..G....Y....HF....D.T.......ASRKKAVANIFE........NIDQE..SLQR.LFRNSG....D..K...K..A....E...E..RA.KIIF..............aIDQDLE.EKTRALMALK.................................
AVPI1_HUMAN/1-75 ..................MGTPASVVSEPP.P..W..Q....A....PI....E.A.......RGRKQASANIFQ........DAELL..QIQA.LFQRSG....D..Q...L..A....E...E..RA.QIIW...............ECAGDH.RVAEALKRLR.................................
A0A1L8H1T3_XENLA/1-74 ..................--MSVSLRVSPS.V..H..G....Y....HF....D.T.......ASRKAAAHNIFQ........GVDQD..SLQR.LFKKSG....D..K...K..A....E...A..RA.RIIF..............cIDQDSE.EKGRALQALR.................................
A0A3Q0E288_CARSF/1-75 ..................MGTPASVVSEPP.R..R..Q....P....PT....E.A.......RGRKQASANIFQ........DAELL..QIQG.LFQRSG....D..Q...L..A....E...E..RA.RIIW...............ECAGDH.RVAEPLRRLR.................................
A0A7L2UPE8_BALRX/10-85 .................p-AMSTSLRVSPS.V..H..G....Y....RF....D.T.......ALRKKAVANIFE........SINEE..SLQK.LFKNSG....D..K...K..A....E...E..RA.KIIL..............aTDQDLE.EKTRALMALK.................................
#=GC seq_cons ...................uhssSlhsuPS.s..+..u....h....th....-.s.......ttRK+AsANIFp........sls.t..pLQ+.LF+sSG....D..c...+..A....E...E..RA.+IIa...............pspD.c.chsRALhuL+.................................
//
