#=GF ID TSP_Ig-like
#=GF AC PF20745.1
#=GF DE Ig-like domain in tailspike protein
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE ECOD:11.21.1
#=GF GA 27.90 27.90;
#=GF TC 28.10 31.90;
#=GF NC 25.70 25.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RC Paper describing PDB structure 2vbe
#=GF RN [1]
#=GF RM 18462681
#=GF RT An intersubunit active site between supercoiled parallel beta
#=GF RT helices in the trimeric tailspike endorhamnosidase of Shigella
#=GF RT flexneri Phage Sf6.
#=GF RA Muller JJ, Barbirz S, Heinle K, Freiberg A, Seckler R, Heinemann
#=GF RA U;
#=GF RL Structure. 2008;16:766-775.
#=GF RC Paper describing PDB structure 4ru4
#=GF RN [2]
#=GF RM 29176754
#=GF RT The O-specific polysaccharide lyase from the phage LKA1
#=GF RT tailspike reduces Pseudomonas virulence.
#=GF RA Olszak T, Shneider MM, Latka A, Maciejewska B, Browning C,
#=GF RA Sycheva LV, Cornelissen A, Danis-Wlodarczyk K, Senchenkova SN,
#=GF RA Shashkov AS, Gula G, Arabski M, Wasik S, Miroshnikov KA, Lavigne
#=GF RA R, Leiman PG, Knirel YA, Drulis-Kawa Z;
#=GF RL Sci Rep. 2017;7:16302.
#=GF RC Paper describing PDB structure 4urr
#=GF RN [3]
#=GF RM 27045683
#=GF RT Bacteriophage Tailspikes and Bacterial O-Antigens as a Model
#=GF RT System to Study Weak-Affinity Protein-Polysaccharide
#=GF RT Interactions.
#=GF RA Kang Y, Gohlke U, Engstrom O, Hamark C, Scheidt T, Kunstmann S,
#=GF RA Heinemann U, Widmalm G, Santer M, Barbirz S;
#=GF RL J Am Chem Soc. 2016;138:9109-9118.
#=GF RC Paper describing PDB structure 5js4
#=GF RN [4]
#=GF RM 28209973
#=GF RT Structural basis for fragmenting the exopolysaccharide of
#=GF RT Acinetobacter baumannii by bacteriophage PhiAB6 tailspike
#=GF RT protein.
#=GF RA Lee IM, Tu IF, Yang FL, Ko TP, Liao JH, Lin NT, Wu CY, Ren CT,
#=GF RA Wang AH, Chang CM, Huang KF, Wu SH;
#=GF RL Sci Rep. 2017;7:42711.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in Tail spike protein (TSP) from Shigella
#=GF CC phage Sf6 and similar sequences from tailed bacteriophages and
#=GF CC bacterial prophages. It forms a beta-sandwich formed by two
#=GF CC antiparallel, three stranded beta-sheets. A short alpha helix is
#=GF CC included in the connecting loop between the third and fourth
#=GF CC strand. This domain is structurally homologous to viral coat
#=GF CC proteins [1].
#=GF SQ 14
#=GS H2BD96_9CAUD/251-340 AC H2BD96.1
#=GS A0A0Q4JGU7_9SPHN/97-188 AC A0A0Q4JGU7.1
#=GS A0A7W6J8I4_9HYPH/294-383 AC A0A7W6J8I4.1
#=GS I2GUG1_9CAUD/625-721 AC I2GUG1.1
#=GS A0A2D2AY32_9CAUL/224-272 AC A0A2D2AY32.1
#=GS I7I026_9CAUD/703-793 AC I7I026.1
#=GS H2BDD0_9CAUD/251-340 AC H2BDD0.1
#=GS I2GUG1_9CAUD/217-308 AC I2GUG1.1
#=GS Q0E5W5_9CAUD/280-368 AC Q0E5W5.1
#=GS H2BD96_9CAUD/654-740 AC H2BD96.1
#=GS Q0E5W5_9CAUD/681-763 AC Q0E5W5.1
#=GS A0A7L8ZGP8_9CAUD/703-793 AC A0A7L8ZGP8.1
#=GS A0A432VA26_9HYPH/362-451 AC A0A432VA26.1
#=GS Q9MC94_BPD3/251-340 AC Q9MC94.1
H2BD96_9CAUD/251-340 ......LTQG.ELVQIGDLSVSVVKG--.ARTLTFAAAPDlapgdvvIVYNPANGSWLADRDPYRAGEMWKVHS...............VSGSTVTIYGNSSSVY-LFSEVDVYRM.
A0A0Q4JGU7_9SPHN/97-188 .....l-GGGeAMTRLPDLAANIIVD--.AQTVTFATVPAlapkdifVVYDSADYSWSASRNYYRAGEMMRTLS...............VAGAVVTIDAPAARAYATGGTREVWK-l
A0A7W6J8I4_9HYPH/294-383 .....r-VQG.ALVLLSKLSANVNKQ--.SRTLQFAAAQPvnpgdvvIVYNPTDFSFGGRRDVYRDGGMFKVHS...............LSGNNLLCYEQATDAY-TAASMDVYR-l
I2GUG1_9CAUD/625-721 ......LQQG.VVSVTSAVNNTATRANViNLKYKYSKAPN.......VIVSVGNLVGSASWDATFFNEDTNVEPlrtptpvnslvaidqVRPAVLW-----NKKVVTPKTFNLYWE.
A0A2D2AY32_9CAUL/224-272 pagqfa----.-----------------.-----------.......----------AANRANYRAGEMVEVKA...............VAGAVVTLDGPLHAAY-APADVQLWKM.
I7I026_9CAUD/703-793 .....t-VGGaFFSDNEKIKATVTGQTY.-----------.......LQSNALNWASNGYAKAAGTKIVIPGAGanggdlvttiaratyVTNSLYTIDIADPIVTPTAENTQIKA-l
H2BDD0_9CAUD/251-340 ......LTQG.ELVQIGDLSVSVVKG--.ARTLTFAAAPDlapgdvvIVYNPANGSWLADRDPYRAGEMWKVHS...............VSGSTVTIYGNSSSVY-LFSEVDVYRM.
I2GUG1_9CAUD/217-308 .....y-ASG.SHTQITTLASDIVKNQ-.SQSFDVADASQiqkgdwlVIYCTDDFSYSPYRNYYRKGEFVEVAS...............VSGNTVKFFGRAYDNYLTSENIVILKV.
Q0E5W5_9CAUD/280-368 .....s-CVG.SLVALPNIS-SVSAG--.SLTIDFASTPNlvagdvfIIYNPTDSSFSGFRTSYRAGEFCEVRA...............VSGNTVTIRSALYAAY-DGATVAIYKV.
H2BD96_9CAUD/654-740 ......HQSG.AVNVTTTASATVAAPAQ.TIRYPYSKIPN.......VSVQVSSQSGGGQ---SAIGSITPVAIaynv.......qpnsIRPAIM----APSGSFAAGGSARLHW-s
Q0E5W5_9CAUD/681-763 .....v-LGG.RVQVTTATNASSVTAPV.TFRYIYPKAPT.......VQVTKTDRSYAGNRVGVAIANPTS---...............ASGATLGLFTDDGTNFSSAVTNQLNWQ.
A0A7L8ZGP8_9CAUD/703-793 .....t-VGGaFFSANEKIKATVTGQTY.-----------.......LQSNALNWASNGYAKAAGTKIVIPGAGanggdlvttiaratyVTNSLYTIDIADPIVTPTAENTQIKA-l
A0A432VA26_9HYPH/362-451 .....a-TSG.IATRVGDLSANVAKG--.SRTLSFTSVDGieefdllCLYNPTDYSWSGHRASYREGEFCRVHS...............ISGNTVTIYGQTYDPY-TAANMQVYRV.
Q9MC94_BPD3/251-340 ......LTQG.ELVQIGDLSVSVVKG--.ARTLTFAAAPDlapgdvvIVYNPANGSWLADRDPYRAGEMWKVHS...............VSGSTVTIYGNSSSVY-LFSEVDVYRM.
#=GC seq_cons .......stG.thsthsslusoVsts...shphpautsss.......llhsssshSauupRssYRsGEhhcVtu...............VoGuslTl.ssssssY.suusspla+..
//
