#=GF ID Tax
#=GF AC PF02959.20
#=GF DE HTLV Tax
#=GF PI HTLV_tat;
#=GF AU Bateman A;0000-0002-6982-4660
#=GF AU Jeang K;
#=GF SE Pfam-B_1456 (release 6.4)
#=GF GA 27.00 27.00;
#=GF TC 463.10 462.80;
#=GF NC 22.20 19.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 11325603
#=GF RT Functional activities of the human T-cell leukemia virus type I
#=GF RT Tax oncoprotein: cellular signaling through NF-kappaB.
#=GF RA Jeang K;
#=GF RL Cytokine Growth Factor Rev 2001;12:207-217.
#=GF DR INTERPRO; IPR004120;
#=GF DR SCOP; 1ao7; fa;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Human T-cell leukaemia virus type I (HTLV-I) is the etiological
#=GF CC agent for adult T-cell leukaemia (ATL), as well as for tropical
#=GF CC spastic paraparesis (TSP) and HTLV-I associate myelopathy (HAM).
#=GF CC A biological understanding of the involvement of HTLV-I and in
#=GF CC ATL has focused significantly on the workings of the
#=GF CC virally-encoded 40 kDa phospho-oncoprotein, Tax. Tax is a
#=GF CC transcriptional activator. Its ability to modulate the
#=GF CC expression and function of many cellular genes has been reasoned
#=GF CC to be a major contributory mechanism explaining HTLV-I-mediated
#=GF CC transformation of cells. In activating cellular gene expression,
#=GF CC Tax impinges upon several cellular signal-transduction pathways,
#=GF CC including those for CREB/ATF and NF-kappaB [1].
#=GF SQ 9
#=GS B8LHM2_9DELA/3-224 AC B8LHM2.1
#=GS TAX_HTL1A/3-224 AC P03409.2
#=GS Q9QR98_9DELA/22-243 AC Q9QR98.1
#=GS Q9QR97_9DELA/3-224 AC Q9QR97.1
#=GS TAX_HTL32/3-224 AC Q0R5R1.1
#=GS Q98621_9DELA/3-224 AC Q98621.1
#=GS TAX_HTL1C/3-224 AC P14079.2
#=GS Q8URS9_9DELA/3-224 AC Q8URS9.1
#=GS TAX_HTLV2/3-224 AC P03410.2
B8LHM2_9DELA/3-224 HFPGFGQSLLYGYPVYVFGDCVQADWCPISGGLCSPRLHRHALLATCPEHQITWDPIDGRVVGSPLQYLIPRLPSFPTQRTSKTLKVLTPPTTPVTPKVPPSFFQSVRRHSPYRNGCLETTLGEQLPSLAFPEPGLRPQNVYTIWGKTIVCLYIYQLSPPMTWPLIPHVIFCNPRQLGAFLSNVPPKRLEELLYKLYLHTGAIIILPEDALPTTLFQPVRAP
TAX_HTL1A/3-224 HFPGFGQSLLFGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPITHTTPNIPPSFLQAMRKYSPFRNGYMEPTLGQHLPTLSFPDPGLRPQNLYTLWGGSVVCMYLYQLSPPITWPLLPHVIFCHPGQLGAFLTNVPYKRIEELLYKISLTTGALIILPEDCLPTTLFQPARAP
Q9QR98_9DELA/22-243 HFPGFGQSLLFGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPITHTTPNIPPSFLQAMRKYSPFRNGYMEPTLGQHLPTLSFPDPGLRPQNLYTLWGGSVVCMYLYQLSPPITWPLLPHVIFCHPGQLGAFLTNVPYKRIEELLYKISLTTGALIILPEDCLPTTLFQPVKAP
Q9QR97_9DELA/3-224 HFPGFGQSLLFGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPITHTTPNIPPSFLQAMRKYSPFRNGYMEPTLGQHLPTLSFPDPGLRPQNLYTLWGGSVVCMYLYQLSPPITWPLLPHVIFCHPGQLGAFLTNVPYKRIEELLYKISLTTGALIILPEDCLPTTLFQPVKAP
TAX_HTL32/3-224 HFPGFGQSLLYGYPVYVFGDCVQADWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVVSSALQYLIPRLPSFPTQRTTRTLKVLTPPTTAATPKIPPSFFHAVKKHTPFRNNCLELTLGEQLPAMSFPDPGLRPQNIYTMWGSSVVCLYLYQLSPPMTWPLIPHVIFCHPEQLGAFLTRVPTKRLEELLYKIFLSTGAIIILPENCFPTTLFQPTRAP
Q98621_9DELA/3-224 HFPGFGQSLLYGYPVYVFGDCVQADWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVVSSALQYLIPRLPSFPTQRTTRTLKVLTPPTTATTPKVPPSFFHAVRKHTPFRNNCLELTLGEQLPAMSFPDPGLRPQNVYTMWGSSVVCLYLYQLSPPMTWPLIPHVIFCHPEQLGAFLTRVPTKRLEELLYKIFLSTGAILILPENCFPTTLFQPTRAP
TAX_HTL1C/3-224 HFPGFGQSLLFGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPITHTTPNIPPSFLQAMRKYSPFRNGYMEPTLGQHLPTLSFPDPGLRPQNLYTLWGGSVVCMYLYQLSPPITWPLLPHVIFCHPGQLGAFLTNVPYKRIEKLLYKISLTTGALIILPEDCLPTTLFQPARAP
Q8URS9_9DELA/3-224 HFPGFGQSLLYGYPVYVFGDCVQADWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVVSSALQYLIPRLPSFPTQRTTRTLKVLTPPTTATTPKVPPSFFHAVKKHTPFRNNCLELTLGEQLPAMSFPDPGLRPQNVYTIWGCSVVCLYLYQLSPPMTWPLIPHVIFCHPEQLGAFLTRVPTKRLEELLYKIFLSTGAIIILPENCFPTTLFQPTRAP
TAX_HTLV2/3-224 HFPGFGQSLLYGYPVYVFGDCVQADWCPVSGGLCSTRLHRHALLATCPEHQLTWDPIDGRVVSSPLQYLIPRLPSFPTQRTSRTLKVLTPPTTPVSPKVPPAFFQSMRKHTPYRNGCLEPTLGDQLPSLAFPEPGLRPQNIYTTWGKTVVCLYLYQLSPPMTWPLIPHVIFCHPRQLGAFLTKVPLKRLEELLYKMFLHTGTVIVLPEDDLPTTMFQPVRAP
#=GC seq_cons HFPGFGQSLLaGYPVYVFGDCVQuDWCPISGGLCSARLHRHALLATCPEHQITWDPIDGRVluSALQaLIPRLPSFPTQRTS+TLKVLTPPhTtTTPplPPSFhQAhRKaoPFRNGhhEsTLGppLPoLSFPDPGLRPQNlYTlWGuSVVChYLYQLSPPhTWPLlPHVIFCHPtQLGAFLTpVPhKRlEELLYKI.LoTGAlIILPEDCLPTTLFQPsRAP
//
