#=GF ID TetR_C_37
#=GF AC PF18665.5
#=GF DE Tetracyclin repressor-like, C-terminal domain
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF08067
#=GF GA 27.00 27.00;
#=GF TC 28.90 28.10;
#=GF NC 26.60 26.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF CL CL0174
#=GF RN [1]
#=GF RM 18208836
#=GF RT Crystal structure of IcaR, a repressor of the TetR family
#=GF RT implicated in biofilm formation in Staphylococcus epidermidis.
#=GF RA Jeng WY, Ko TP, Liu CI, Guo RT, Liu CL, Shr HL, Wang AH;
#=GF RL Nucleic Acids Res. 2008;36:1567-1577.
#=GF DR INTERPRO; IPR041646;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC IcaR belongs to the tetracycline repressor (TetR) family of
#=GF CC proteins, which are involved in a wide variety of gene
#=GF CC regulations. It binds to a 42 bp region immediately upstream of
#=GF CC the icaA gene. This entry represents the C-terminal domain which
#=GF CC is involved in dimerization [1].
#=GF SQ 95
#=GS A0A1G6NEK7_NIADE/81-197 AC A0A1G6NEK7.1
#=GS A0A4R1AI86_9FLAO/81-198 AC A0A4R1AI86.1
#=GS A0A1H9QN33_9SPHI/80-196 AC A0A1H9QN33.1
#=GS A0A291QXU8_9BACT/81-197 AC A0A291QXU8.1
#=GS A0A4U1CBJ9_9SPHI/80-196 AC A0A4U1CBJ9.1
#=GS ICAR_STAEQ/71-181 AC Q5HKQ1.1
#=GS A0A1T4ZZU5_9SPHI/81-197 AC A0A1T4ZZU5.1
#=GS A0A1G9HKK7_9BACT/79-196 AC A0A1G9HKK7.1
#=GS A0A1Y1SYI3_9FLAO/81-198 AC A0A1Y1SYI3.1
#=GS I5AYX0_9DELT/81-197 AC I5AYX0.1
#=GS A0A0E9MY98_9BACT/81-197 AC A0A0E9MY98.1
#=GS A0A074LFY5_9BACT/81-197 AC A0A074LFY5.1
#=GS W2UPV7_9FLAO/79-196 AC W2UPV7.1
#=GS A0A7G9S186_9FIRM/86-197 AC A0A7G9S186.1
#=GS A0A6J4Y895_9DELT/81-194 AC A0A6J4Y895.1
#=GS K2Q4X5_9FLAO/79-196 AC K2Q4X5.1
#=GS A0A1V9GDC6_9BACT/81-197 AC A0A1V9GDC6.1
#=GS A0A1G6ZS59_9SPHI/91-207 AC A0A1G6ZS59.1
#=GS A0A1H8GHM4_9BACT/79-195 AC A0A1H8GHM4.1
#=GS I5B2F8_9DELT/83-199 AC I5B2F8.1
#=GS I3C9V0_9FLAO/81-198 AC I3C9V0.1
#=GS A0A4R3KUA6_9SPHI/81-197 AC A0A4R3KUA6.1
#=GS A0A318UDG3_9SPHI/80-196 AC A0A318UDG3.1
#=GS A0A1G9P1Q4_9BACT/81-197 AC A0A1G9P1Q4.1
#=GS A0A0U3BHV5_9FLAO/81-196 AC A0A0U3BHV5.1
#=GS A0A1K1RLQ7_9FLAO/81-197 AC A0A1K1RLQ7.1
#=GS A0A1H0LW20_9DELT/83-199 AC A0A1H0LW20.1
#=GS A0A5K7YS08_9DELT/92-206 AC A0A5K7YS08.1
#=GS A0A3D8Y315_9BACT/81-197 AC A0A3D8Y315.1
#=GS A0A1H6QAX1_9BACT/81-197 AC A0A1H6QAX1.1
#=GS A0A1M7XW57_9DELT/83-198 AC A0A1M7XW57.1
#=GS A0A1M7Y8R4_9DELT/83-198 AC A0A1M7Y8R4.1
#=GS A0A1V9G034_9BACT/80-196 AC A0A1V9G034.1
#=GS A0A1M5VD17_9BACT/80-196 AC A0A1M5VD17.1
#=GS A0A4R6SQ06_9SPHI/80-196 AC A0A4R6SQ06.1
#=GS ICAR_STAA8/66-182 AC Q9RQQ0.1
#=GS A0A1D7QBR8_9SPHI/80-196 AC A0A1D7QBR8.1
#=GS A0A150X722_ROSEK/79-195 AC A0A150X722.1
#=GS A0A1H4YXX2_9FLAO/81-198 AC A0A1H4YXX2.1
#=GS A0A8J7IXN2_9FLAO/79-196 AC A0A8J7IXN2.1
#=GS A0A512RDN6_9BACT/81-197 AC A0A512RDN6.1
#=GS A0A4R0NKR1_9SPHI/80-196 AC A0A4R0NKR1.1
#=GS A0A7W0HM09_9DELT/89-205 AC A0A7W0HM09.1
#=GS A0A150X585_9BACT/79-195 AC A0A150X585.1
#=GS A0A7K1XWG5_9SPHI/80-196 AC A0A7K1XWG5.1
#=GS A0A1A7R143_9FLAO/81-121 AC A0A1A7R143.1
#=GS A0A380GX36_9STAP/70-181 AC A0A380GX36.1
#=GS H1XZQ1_9SPHI/80-196 AC H1XZQ1.1
#=GS F0RAB8_CELLC/81-198 AC F0RAB8.1
#=GS A0A850SYA6_9DELT/81-197 AC A0A850SYA6.1
#=GS A0A6P1ME40_9FIRM/82-198 AC A0A6P1ME40.1
#=GS A0A3B7MML5_9BACT/81-197 AC A0A3B7MML5.1
#=GS A0A399T7J7_9BACT/79-195 AC A0A399T7J7.1
#=GS H6L2I9_SAPGL/94-211 AC H6L2I9.1
#=GS A0A238UAW3_9FLAO/88-205 AC A0A238UAW3.1
#=GS A0A4V1B3M3_9SPHI/81-196 AC A0A4V1B3M3.1
#=GS A0A1I1KXF8_9SPHI/26-79 AC A0A1I1KXF8.1
#=GS A0A1I0VRY3_9BACT/81-194 AC A0A1I0VRY3.1
#=GS A0A553FRP7_9BACT/81-197 AC A0A553FRP7.1
#=GS A0A7Y7ECP8_9BACT/98-214 AC A0A7Y7ECP8.1
#=GS A0A0Q0UXJ3_9SPHI/80-196 AC A0A0Q0UXJ3.1
#=GS R7ZRC9_9BACT/81-194 AC R7ZRC9.1
#=GS A0A7Y9HTQ9_9SPHI/80-196 AC A0A7Y9HTQ9.1
#=GS A0A1M6B0Q8_9BACT/79-195 AC A0A1M6B0Q8.1
#=GS A0A4U0NZ49_9SPHI/81-197 AC A0A4U0NZ49.1
#=GS A0A1A9I8J6_9BACT/81-196 AC A0A1A9I8J6.1
#=GS A0A127VFZ5_9SPHI/79-194 AC A0A127VFZ5.1
#=GS C0Q9G9_DESAH/81-190 AC C0Q9G9.1
#=GS A6EBB4_9SPHI/80-196 AC A6EBB4.1
#=GS A0A1H0SCQ6_9DELT/81-197 AC A0A1H0SCQ6.1
#=GS A0A1M7NZ77_9BACT/81-194 AC A0A1M7NZ77.1
#=GS A0A4V5NS91_9DELT/83-199 AC A0A4V5NS91.1
#=GS A0A5K8AHU4_9DELT/81-196 AC A0A5K8AHU4.1
#=GS A0A1G5AN96_9DELT/82-197 AC A0A1G5AN96.1
#=GS Q4A0X6_STAS1/69-168 AC Q4A0X6.1
#=GS A0A2R7K441_9SPHI/80-196 AC A0A2R7K441.1
#=GS A0A3S2Y2X8_9SPHI/80-196 AC A0A3S2Y2X8.1
#=GS A0A4R5DD85_9BACT/81-197 AC A0A4R5DD85.1
#=GS A3HUN0_9BACT/81-194 AC A3HUN0.1
#=GS A0A5C0ZQT0_9SPHI/80-196 AC A0A5C0ZQT0.1
#=GS A0A5B8VRD5_9BACT/81-197 AC A0A5B8VRD5.1
#=GS U5BYR1_9BACT/81-197 AC U5BYR1.1
#=GS W0EYV0_9BACT/80-196 AC W0EYV0.1
#=GS A0A4R6IGQ8_9SPHI/80-196 AC A0A4R6IGQ8.1
#=GS A0A1W2C6N9_9SPHI/80-196 AC A0A1W2C6N9.1
#=GS A0A1M7YEQ6_9DELT/83-199 AC A0A1M7YEQ6.1
#=GS A0A2D1U0C6_9SPHI/80-196 AC A0A2D1U0C6.1
#=GS A0A316B4W2_9BACT/81-197 AC A0A316B4W2.1
#=GS A0A554VPX4_9FLAO/81-198 AC A0A554VPX4.1
#=GS A0A7Y9HTA0_9SPHI/81-196 AC A0A7Y9HTA0.1
#=GS A0A1M7ZAD2_9BACT/81-194 AC A0A1M7ZAD2.1
#=GS A0A1I0QWR0_9BACT/79-195 AC A0A1I0QWR0.1
#=GS A0A2K8XM28_9FLAO/80-197 AC A0A2K8XM28.1
#=GS G0J6D3_CYCMS/81-194 AC G0J6D3.1
#=GS A0A6J4XF13_9DELT/67-185 AC A0A6J4XF13.1
A0A1G6NEK7_NIADE/81-197 ...................hpk---RKLLAVIDNIF..SHKWNT.LFDD.SVS.YS..CYSLTFRDKTIKKKYKLLLDSLRKNLETLIIDCNENGYLQV.KNTAAVADLVFILVDGAYYYLSL...VSDKAEYEKKLSTYKKRALGLLN-f...........................
A0A4R1AI86_9FLAO/81-198 .....................t-SKEALHQFIEKLF..SREWNN.YIDD.GVF.YS..LYALIYRNEKVNDSFRSFGASLRKVLKSKLLSAKEHNIIKN.PNIEELNEIIFAMIDGGYFYLGT..qMRNETSYQQQSSIYIKHVLSLFH-f...........................
A0A1H9QN33_9SPHI/80-196 .....................a-TITDLQRTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKQKYKVILDALRTGLSTMIDQCNAQSLTKI.SDPQAVADFIFVLVDGAYFYLSM...ESDKKAYNERLEAYKQRAYDALSI............................
A0A291QXU8_9BACT/81-197 ..................dprk----ILLKVMDNIF..SHKWNL.LFDD.SVS.YS..CYSLAFRDQKVKESYKVLLDTLRGNLRDLIEECNQQGVLKV.KDPAAVADTIFVMVDGAYYYLSL...VSNKREYKKKLEQYKSLALQQLN-f...........................
A0A4U1CBJ9_9SPHI/80-196 ....................vt--LSDLQKTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKEKYKSILDSLRFALTSMIERCNEKEFTKV.EDPKTAADLIFVLVDGAYFYLSL...ESDKKAYAERLHYYKNKAYQILGI............................
ICAR_STAEQ/71-181 .....................y-SIDGLYQFL----..---FKF.IFDV.DER.YIklYVQLSSAPEALNSEIKHHLQEINTTLHDELIKYYDPTHIAL.-DKEDFINLILLFLETWYFRASF...SQKFGIIEDSKNRFKDQVYSLLNV............................
A0A1T4ZZU5_9SPHI/81-197 .....................p-SADTLAVVIDDLF..SRKWNK.LFDD.GLF.YS..CYALTFREKKVKEMYRKLTDSLRLRLTALIQRCNDAGLIEV.DNPRLTADLIFALVDGAYFYLSV...SANAKAFDEKIKDYKAEAYRLLGI............................
A0A1G9HKK7_9BACT/79-196 .....................a-TREALVETIDKLF..SKKWND.LFDD.GLS.FS..CYALIFRNETVKEKFKSVLDLLHTRLATLIRQCAENGEIRLtEDPRVVADLIFVIVDGAYYYLSL...VSDPAEFDRKLTEYKLRALRLLSI............................
A0A1Y1SYI3_9FLAO/81-198 .....................d-NKESLVNFITDLF..SRKWNK.YFDD.GVF.YS..CYALIYRKKDFNTSFRNYLEKLHQVLQEKLLEAKSCGVIFN.SNISEITEIIFALIDGSYYYLGM..fNQKEINYREKEELYIIYAIKLLD-f...........................
I5AYX0_9DELT/81-197 sskermetllgilfdasgtwpq--------------..------.--RD.AVF.WS..CYAMGFRDENIRERIRDMMLKFIEFGIEEIAGWEETGLASV.ENKKRASAKIFALSEGFGIVKNS...LDDPELIKEVADFFKNTTLKILN-c...........................
A0A0E9MY98_9BACT/81-197 .....................n-CRNQLVTVIDNLF..SNKWNA.LFDD.GVS.YS..CYALVFRDKTIKSKYKDVLDQLRNTLEGLIVQCVAEKRITC.ANPAAIADMIFVLVDGAYYYLSL...TSSKEEYAKRLQLYKRYALDLLHL............................
A0A074LFY5_9BACT/81-197 .....................d-SSQMLPSLINRMF..SKDWND.LFDD.GVY.YS..AYAMVFREPKFREKFSKIHKILRLKLSELLKECNETGMIKC.INPDQTANQIFFLLDGTYFYINM...LETYKEQNEHLESSKKLAYSILGL............................
W2UPV7_9FLAO/79-196 .....................d-SRTKLISTINNLF..SREWNS.LIDD.GVF.YS..SFALVFRNKAIQEAYKNMHQSLRNYLTEVIKEAQTDNVVEV.ENAKETAELIFILVEGSYYYLSL..yDASTPVYEEKIKRYKKAALEMLKI............................
A0A7G9S186_9FIRM/86-197 ..............kiqdffva--------------..-----S.MFDE.SIFkYIsnSFELLNSPKFFLKYIDYVNQTLVPYIEDALVEGNEDGSLSM.DHPKQTAELIVLVLSTWFLNAIF...PNTIETFEQKIHVSQK--------flknnhldild.................
A0A6J4Y895_9DELT/81-194 ....................dp--SQKIQAFLDLIF..SSEYSN.LGGP.LVY.LE..LMALALRNDKVRISFSRFNENFRNVLKTEFSKLEQNDA-SA.YDHQQIVELIIYLTEGFHL-WGF...ARNDSKSKTTAN------------flklmildlag.................
K2Q4X5_9FLAO/79-196 .....................t-TQEELITFIESLF..SRKWNR.YFDD.GVF.YS..CYALVYRKKEFRDSFKNYLDALHEVLKSNLTQAYQNNLIST.QDLDEVTEIIFALIDGGYYYLGL..fQHDKDKYQQQIELYVKYALKLLGI............................
A0A1V9GDC6_9BACT/81-197 ...................epk---KALLKVIDNIF..SAKWNT.LFDD.SVS.YS..CYALAFRDKTIKEKYKRLLDTLRQNLQQLIMDCKAQGILSV.KDPALTADLIFVLVDGAYYYLCL...VSDKEEYKQKLALYKKQAISLLNL............................
A0A1G6ZS59_9SPHI/91-207 ....................vt--LADLQKTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKLKYKTILDSLRHALSSMIEQCNEKQLINV.LAPKTAADLIFVLVDGAYFYLSL...ENDKEAYTARLEYYKHKAYEILGM............................
A0A1H8GHM4_9BACT/79-195 .....................s-AIDRLRGVLDNLF..SAKWNR.LVDD.GLF.YS..CYALSFRDKKVKELYKALHDRLRASLAELILECKLQNGLKV.GNPGHAAQVVYVLVDGAYYYLKL...VSDKAEYSQKLAIYKEQAFQVLGL............................
I5B2F8_9DELT/83-199 .................dsarr-----FDAMMDLIF..SFKWNR.TVDP.GVH.FG..FYYKSFRDEGIRKVFKDMFRWLSDYLYNAFILFNKDSIIKV.TDERKAAEYVLTLMKGLEFHAHF...LNEGRPFEDFANTAKTATIAML--kn..........................
I3C9V0_9FLAO/81-198 ......................NSKEELHNFITTLF..SRKWNR.YFDD.GVF.YS..CYALVYRKPAFNASFKRYLELLHEVLKDKLIEAHTNGVIKN.NNIDEVTEVIFALIDGGYYYLGL..fNESEEAYKKQVDIYVSYAVNLLD-f...........................
A0A4R3KUA6_9SPHI/81-197 .....................a-SKEALMEMINALF..SKKWNV.LFDD.KVS.YS..CYALIFRNKKIRMRYKSVLDSLHHTLAAFIEKCRKENILQT.EDPVFASRIIFALVDGAYYYLSL...EDDKDQYRLRLEQYKQRAISVLNL............................
A0A318UDG3_9SPHI/80-196 ....................it--LSDLQKTIDKLF..SKKWNL.LFDD.GLF.YT..FYAMSFRDKIIREKYKKILDSLRFELAAIMIKCKEKQLLNI.ADPQATADLIFVLLDGAYFYLSL...EKDKTVYSERLDSYKAKAYEFLG-w...........................
A0A1G9P1Q4_9BACT/81-197 .....................d-ALERLVSILDNIF..SRKWNR.LIDD.GVF.YS..CFALVFRDPRIRTKFRELHLVLRQWLAETIQACMDQGVLTV.QDATHTADLIFVISDGAYYYLSL...IDDEAAYQERLQAYRQEAFRLLQL............................
A0A0U3BHV5_9FLAO/81-196 ....................kh--KNDLNAFIKNLF..TRKWND.YIDD.GVF.YS..LYALIYRDEELRENFNNFNKILHLALHKKLTQAKERHIISN.DNIDTLTEIIFAMIDGGYYYLGT..qTNDSETYNKQVEIYLNHI------ntfi........................
A0A1K1RLQ7_9FLAO/81-197 .....................d-TWDRLEKLVENLF..SRKWNR.YFDD.GVF.YS..CYALIYRKKDFNESFRKYLEELHTVLKDKLLEARAHGVICN.ENLEELTEIIFALIDGAYYYLGM..fTERSAEYEKQEKLYIRHTMSL---fr..........................
A0A1H0LW20_9DELT/83-199 ..................ddqe----RFDALMDMIF..SYEWSR.TVDP.GVH.FG..FYYQSFRDEHVHKLFTDMFVWFRDFLHDQFVDFNRKGVIQV.SDEVKAADFVLTMMEGLEFHAHF...LAGDNPFEDFAQSCKKTAYTILK-n...........................
A0A5K7YS08_9DELT/92-206 ...................dde---EHFDSLISMIF..SLQWSR.TVDP.SVH.FG..FYYLSLRNEKILERFRVMFKWLRDYLREKLVYFNAKGVINV.KDEKKAADYIVTLMEGL------...------------------------eihnqfladgkpfedfaqvaqkalvsal
A0A3D8Y315_9BACT/81-197 ......................NSQAALLEIVDNIF..SKKWNT.LFDD.GLF.YS..CYSLTFREPKIRELYKSILDALRKKLSEHIAQCHKEGLINV.EDPDQIADDIFVLVDGAYFYLSL...VTDKKDYEKRIQKYKQRAIAMLR-l...........................
A0A1H6QAX1_9BACT/81-197 ....................ta--REILLAVIDNLF..SKQWNK.LFDD.GLF.YS..CYALSFRDEKIKNRYHSLLSSLRAKLTEIIEAANQDGSLSI.ERPSECADLIFIILDGAYFYLSL...SKDPILTKSKLALYKEKALKVLEI............................
A0A1M7XW57_9DELT/83-198 ....................pl---ERLERLLQLVW..SREWHE.AASF.AVV.FS..FLALSQRDDEVRKRVRNLYNNYRRYLQVQVCFFAEEGVIRI.DDVEAAVEALISLSEGSHYFCRF...HIDNGTFDSHCQHMIVAAKRIL--gv..........................
A0A1M7Y8R4_9DELT/83-198 ................dpnery------AALLDLIF..SLQWSR.TVDP.GVH.FG..FYYQSFRDQRTLEHLQGMFAWLRDYIEEQLVIFNDHGIITV.QEPRKAADYIVTLMEGMEFHSQF...LRDGKPFEDFSESVKTSVRALL--a...........................
A0A1V9G034_9BACT/80-196 ....................pt--LADLKKMIDNLF..SKKWNN.LFDD.GLF.YS..CYALTFRDKKIKQMYHSIGSTLRSRLASFIESCNKGKILSV.KNVEEVADKLFVLVDGSYFYVSV...INDKKEYEKIVIRHKAAAYSLLGI............................
A0A1M5VD17_9BACT/80-196 ....................tn--ARELKQLIDNLF..SRKWNK.LFDD.SVF.YS..CYALVYRDKKIRSAFKALHESLRKLLTDALQKANKNGVINI.RNEKETVEIIFALMEGAYYYLGM...VDSKTDYTRKLNMLKKHALLQ---lgl.........................
A0A4R6SQ06_9SPHI/80-196 ....................vt--LSDLQKTVEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKVKYKAILDSLRLALASMIEQCNVKHITEV.KDPQTTADFIFVLVDGAYFYLSL...ESDNKAYGERLDFYKDQAYQILGI............................
ICAR_STAA8/66-182 ...............nqnksny-SIDALYQFL----..---FEF.IFDI.EER.YIrmYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKM.-TKEDFQNLILLFLESWYLKASF...SQKFGAVEESKSQFKDEVYSLLNI............................
A0A1D7QBR8_9SPHI/80-196 .....................v-TIADLQKTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKIKYKAILDSLRFTLAMIIEQCNQTNELKI.SDPKSTADLIFVLVDGAYFYLSM...ESDKLAYQKKLDDYKRNAYQILGI............................
A0A150X722_ROSEK/79-195 .....................s-AIDHLREVLNNLF..SRKWNA.LISD.DVY.YS..CYSLIFRNNVIRSKYKDLHDSLRVWLESHLVECIEEGSLKL.ENPKRTANLIYTILEGAYYYLCM...EKNAAKKDEIMGQYKQHAYDILKL............................
A0A1H4YXX2_9FLAO/81-198 .....................t-SKENIEAYIDLLF..SRDWSD.YIDD.GVF.YS..FYALIYQNDKVRENFKAHHEELIKVLQLKLSEAVLGGVLRN.QNIERLTRVIFALVDGAYYTLGV..fIKEELEYNKRVMLFSSHAKSLLK-y...........................
A0A8J7IXN2_9FLAO/79-196 ....................ss--DVKLLQTIDNLF..SRDWNN.LIDD.GVF.YS..CYTLIFRDDNIKTAFKDLHDSLREFLAEIIEDAKKDGIIDV.TDSKETAELIFVLVEGAYYYLSL..fDTNDKTYIEKTERYKQAALQMLN-f...........................
A0A512RDN6_9BACT/81-197 ...................dph---KKLLKVIDNIF..SHKWNV.LFDD.SVA.YS..CYSLVFRDQKVKENYKVLLDTLRGNLRALIEECNQQGVLKV.KDPAAVADTIFVMVDGAYYYLSL...VSNKKEYKQKLAQYKGLALQQLNL............................
A0A4R0NKR1_9SPHI/80-196 .....................i-TLEDLHHTIETLF..SKKWNL.LFDD.GLF.YT..FYALAFREKRIKEKYKTILDSLRQGLAALIVQCNEKKLIAV.KDPQITADHIFVLVDGAYFYLSL...ENDNKAYTERLEYYKNQAFQILGI............................
A0A7W0HM09_9DELT/89-205 ...................epa---ARLEKLIEIIW..SRQYYE.KIHI.ASS.FS..MIAVSFRNPRIHEKIQGLYASFQHFLAKEIQRACDAGAIEA.QDSVRAANRVITLVEGARHFRHFfvhHNRVKQYNHDMKEATK--------mmlkm.......................
A0A150X585_9BACT/79-195 .....................s-AIDQLMEVLNNIF..SRKWNT.LVSD.DVY.YN..CFTLIFRDPLIQKKYRQLHDSLRESLTEHLEACIDEGSLQL.DDPKITANLIYTILEGAYFYLCM...VPDTQTRTEVMDQHKKHAFAILGM............................
A0A7K1XWG5_9SPHI/80-196 .....................a-TLRNLQNTIEMLF..SKKWNL.LFDD.GLF.YT..FYALIFREHKIKVKYKMILDSLRQGLAAIIEQCNAKALTSV.KDPQTTADLIFVLVDGAYFYLSL...ESDKAAYAERLSYYKQKAYEALAI............................
A0A1A7R143_9FLAO/81-121 ....................dc--KVDVIRFIEDLF..GRASIV.YFDD.GFL.YS..CYALIYRVAEFR-----------------------------.-----------------------...------------------------............................
A0A380GX36_9STAP/70-181 ....................ny-SIDGLYQFL----..---FKF.IFDV.DER.YIklYVQLSNAPEALSSEINDYLKEVNETINSEIIKYYDPSYISM.-DKEDFKNLIFLFLESWYLRASF...SQRYGGIEDSKNNFKDEVCSLLNV............................
H1XZQ1_9SPHI/80-196 .....................a-TLANLRHTIEMLF..SKEWNL.LFDD.GLF.YT..FYALAFREEKIKVKYKIILDSLRHGLAAIIEQCNEKGLTSV.KSPQTAADFIFVLVDGAYFYLSL...ENDIEAYTERLNYYKQKAYEILEI............................
F0RAB8_CELLC/81-198 ......................NSKQKLHNLITSLF..SRNWNK.YFDD.GVF.YS..CYALIYRKKDFNDSFKSYLQALHTVLHKKLTEAKEHQIISN.TNIDEITEVIFALIDGAYYYLGL..fNEKTEDYKQKEAIYIKYALNILE-f...........................
A0A850SYA6_9DELT/81-197 ...............sarerme-------TLLEILF..DAGGTW.PQRD.AVF.WS..CYAMGFRDEKIREKIRDMMLKFIEFGIEEIAGWEETGLASV.ENKKRASAKIFALSEGFGIVKNS...LDDPELIKEVADFFKNTTLKILN-c...........................
A0A6P1ME40_9FIRM/82-198 ..................dvkg----EFIKFVDSLF..SVNGAI.EIDS.RVY.FS..CVNIALRDKRAKEKFAIYTEKANEKLLKTIEYFSAEGVISC.DNTAEAVYYLMVMIAGLQDTLDF...LDDHEKFQCIADFHKKQLFRFLG-f...........................
A0A3B7MML5_9BACT/81-197 ....................sa--ETALLKVIDNIF..SQKWNT.LFDD.SVS.YS..CYALAFRNKTIKEKYKKLLDTLRLNLAVLIGECKRQGLLEI.EDPAVTADLIFVMVDGAYYYLSL...VTDKKEYQVKLAQYKNQALALLN-f...........................
A0A399T7J7_9BACT/79-195 .....................d-SQEKLLELIDKLF..SRKWNR.LFDD.GVF.YS..CYAMVYRNKQFKEKFKELHDSLRTSLKESLFEAQKNNLIQE.EDVEKLTQVIFALLEGAYYYLGL...VGNKEEYALKVEYYKQQVQTLLHI............................
H6L2I9_SAPGL/94-211 ....................np--QEQFDTVIDILF..GHAWMQ.MSDQhSVF.YA..CYYLSSRHDLIRERFQQMYNRFREVVEELADRWIEAKIVRD.FTPSQVAEYLIMLNEGLTYYEGV...YRDPEAFMHRCQYLQKMVRKTL--ta..........................
A0A238UAW3_9FLAO/88-205 .....................d-SKASLENFIRKMF..TREWSE.YVDD.GVF.YS..LYAMLFRNKNVSESFKTFSNILREVLKSKLNSAKSHGVITN.SNIDELNEIIFAMIDGSYFYLST..qVTNHEICTKQSNIYINHILSLF--rf..........................
A0A4V1B3M3_9SPHI/81-196 .................dlgsf-----LIELIHKLF..-KSWNS.LFNE.SVF.YS..CYALGFRDKLIKMKFKNLQDSLRSHLKEVLDKCNEAGIVNL.PSTEKTADLIYIMVDGAYYYLSL...ISEKEEYEKKLLEYKNYAYQTLGL............................
A0A1I1KXF8_9SPHI/26-79 ..................dlkv----VLVELIDRLF..SKEWNR.LCDD.GLF.YS..CYALNFRDKKVKAMYKQLQDTLR------------------.-----------------------...------------------------gc..........................
A0A1I0VRY3_9BACT/81-194 ....................qn--YADPHTFVDRLF..SRDWNL.LLDD.GVF.YS..CYSLIFRNKRIKDEYRVLHEKLREYLKDILDR---DENLTG.KDTELLSEQIFVVVEGAYYYLSM...FDDPEVYEQKVTIFKNQVYDLL--rk..........................
A0A553FRP7_9BACT/81-197 .....................t-SLEALHEIIDNLF..SRKWNK.LVDD.DVY.YN..CFTFIFRDDAIKEKFKALHDSLRLMLNDILQRCKKDGYLVA.EDTHQLADLVFLFLDGAYYYLSM...VNDPKEYENKMEIYKNKTMEILDI............................
A0A7Y7ECP8_9BACT/98-214 .....................s-AIEELTEVLNNLF..SRKWNN.LVSD.DVY.YN..CFTLTFRDPVIQQKYKQLHDSLRASLEEHLLACIKEGTLQL.EDPKITANLIYTIMEGAYFYLCM...VPDAATRQEIMEQYKRHAFSILGI............................
A0A0Q0UXJ3_9SPHI/80-196 .....................a-TLAELKKTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKEIKAKYKTILDSLRLALATMIEQCNSKNLIKV.TDPQNTADLIFVLVDGAYFYLSL...ENNKKIYSERLAYYKNIAYQVLGI............................
R7ZRC9_9BACT/81-194 ...................sks---LDLEKLVERLF..SREWNL.LFDD.GVF.YS..CYALIFREPAIKKAYRELHLALRETLEGILKQ---DPVLAK.SDTQRLAEQLFVVVEGAYYYLAM...IEDEQEFAAKQAFFKQQVLALLQL............................
A0A7Y9HTQ9_9SPHI/80-196 .....................t-SLERLTEVLNNIF..SKKWNC.YIDD.SVF.YN..CFALIFRNPLIKSRFREMHLLLREWLKNLIQECVDQKLIQC.DDPAHAAELIFVISDGAYYFLSM...IDDPTEYDRHAENYCGEAFKILGL............................
A0A1M6B0Q8_9BACT/79-195 .....................d-SKDKLLALIDHLF..SRSWHR.LFDD.GVF.YS..CYAMIYRNPPVKEKYKLLHDSLLVKFRQSLEEAQNKNIIEI.DNLEETAEVIFSMVDGAYFSLGM...LSDQEERDRKAAVYKQFVKRMLKL............................
A0A4U0NZ49_9SPHI/81-197 ...................dhk---SYLIELIDKLF..SKKWNT.LFND.SVF.YS..CYAMGFRDKKIKEKFKSLQDALRRHLAEILLRCNDSGAIQI.ESPEKTADLIYVLVDGAYYYSSL...VSEKAEYELKLKDYKQYALSVLKI............................
A0A1A9I8J6_9BACT/81-196 ....................kv---SDLRKMIDNLF..SKKWNR.LFDD.GLF.YS..CYALTFRDKRVQQMYLNIAHTLRSRLAAFIAACNREKILSV.KNVDEIADRLFVLVDGSYFYLSV...ITDKKEYEQIVARHKAGAYALLGI............................
A0A127VFZ5_9SPHI/79-194 ....................ml---SDLHKIIEALF..SKKWNL.LFDD.GLF.YA..FYALAFRNKKIKAKYKIILDSLRKTLTSIIERCNEQGLINV.ADPKVAADMIFVLVDGSYFYLSL...EDDKTIYSEKLSFYKNKSYEILGI............................
C0Q9G9_DESAH/81-190 ...................tpe---DRLTQLLESIW..NRDFYE.RIKI.AGS.FA..VLAVSFRNPVIHEKIRELYRMFKTFLVREFTFLMDHQVISI.NEPAHAAEVIMTMIEGSRHFRMF..iIDD---------------------dqmnrynqdmiga...............
A6EBB4_9SPHI/80-196 .....................m-TLEDLQRTVEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKVKYKTILDSLRSALAGMIESCNEKKLIQV.ENPQVTADLIFVLVDGAYFYLSL...EDDKKAYDDRLDYYQAMAFKILGM............................
A0A1H0SCQ6_9DELT/81-197 ..................tpaq----RLKTLIDIFF..EPNGKS.PTRG.KVY.WS..CYAMGLRNEKVWKRIQKLNQKFIEFAISEMELYEKAGLIKV.EDKDLAAITAFTIIEGFGYVRYT...LGDVQKLDQLSRIMKKQAMEALG-v...........................
A0A1M7NZ77_9BACT/81-194 ...............dhkvype-------LLVNRLF..SREWNL.LFDD.GVF.FS..CFAMTFRDETIKREYMKLHLKLRDTLKSILDR---DPVFSK.GDTALLAEKIFVVIEGAYYYLSL...IGDEKEYNRKLNIFKDQVFQLLKL............................
A0A4V5NS91_9DELT/83-199 ..................ddae----RFTALINMIF..SYKWSR.TVDP.GVH.FG..FYYQSFRDANVAVLFREMFQWLRNYLYDEFLIFNSKGIIQV.NDVRKAADFIVTLMEGLEFHAQF...LGHDKPFAEFAETAKQSALAVLK-n...........................
A0A5K8AHU4_9DELT/81-196 .................dddah-----FTALMDVIF..SLKWSR.TVEP.SVH.FG..FYYLSLRNEEIMDRFKVMFKWLRDYLSRKLDYFNSQGVVRV.EDANRAAEYIVTLMEGLEFHSQF...LADG--------------------epfeafsqaakksliralk.........
A0A1G5AN96_9DELT/82-197 ...................dpe---ERLECLLSLIW..SREWYE.AASF.SVV.FS..FLALSQRDAEVMERVRNLYGNYRRYLNKQMALLSDAGVIRV.DDPQATTEALISLSEGSHYFCQY...HIKAGTFDAH--------------cahmirsarlllg...............
Q4A0X6_STAS1/69-168 ...............aahedtq-------YSIENLH..QFLFDF.IFNI.DEK.YIrlYLQLSYALFQFKDEFLQHIKNIHQILDTNIANYYNSIEISV.-NKDEFTTMILMFLESWYLNV--...------------------------asfidmeq....................
A0A2R7K441_9SPHI/80-196 ....................it--LADLQKTIEMLF..SKKWNL.LFDD.GLF.YT..FYALSFREERIKAKYKTILDSLRSELTSMIEQCNKKELLNV.TSPRAAADLIFVLVDGAYFYLSL...ENDKKAYKEKLDDYKNKAYEILGL............................
A0A3S2Y2X8_9SPHI/80-196 ...................dpl---DTLVDVMHNIF..SRKWNN.YIDD.SIF.YN..CFALIFRNQAIKQQFRELHVLLRKWLENLIQSCVDRGLLDH.PDPAMAADLIFVISDGAYYFMSM...IDDPGKYDLHMARYKQEAFKLLRL............................
A0A4R5DD85_9BACT/81-197 .....................d-SKSALLEIIDNLF..SKKWNT.LFDD.GLF.YS..CYSLTFREPKIRDMYKKLLDSLRSILSSHIEQCRIEGLLDV.DDSDSVADNIFVLVDGAYFYLSL...VADKKEHEAKLVKYKEQAIGMLKM............................
A3HUN0_9BACT/81-194 .....................q-NYTDPVTFVERLF..SRDWNL.LIDD.GVF.YS..CFSLIFRNDTIKKEYRNLHLKLREQLKDILDQ---DEKLKE.KDTELLAEQIFVVVEGAYYYLSM...IDEKELYDQKVEIFKNQVYQLLQ-a...........................
A0A5C0ZQT0_9SPHI/80-196 .....................y-SLTDLYDIIDRLF..SKKWNK.LFDD.SLF.YD..FYAESFRNKQIRRKYITILDSLRSMLSTILAKLNDREQLRL.TNPAHTADLIFIFLDGAYFYLSL...VEDKSMVENRLNQYKEEVYDLLKL............................
A0A5B8VRD5_9BACT/81-197 .....................s-SIQVLTQVIERLF..SHKWNA.LFDD.SVS.YS..CYSLTFRDRVIQEKYRNVLNALREQLEILIANCKANKEINV.ADPATTADLIFVLVDGAYYYLSL...ISDKKEYKRHLKIYKEQAIKLLNI............................
U5BYR1_9BACT/81-197 ......................NSSDVLYALVQRMF..SKDWND.LFDD.GVY.YS..AYALVYREPQVKEKFNKIHKTLRAKFSSLLKECDAFGHINC.KEPDQTSNLIFSLLDGTYYFINM...LDTDTEQKEHLKQSEELAFKILGL............................
W0EYV0_9BACT/80-196 .....................p-TLTDLKKVIDNLF..SKQWNS.LFDD.GLF.YS..CYALTFRDKKVKQMYHTIGSTLRSRLAVFLASCKHEKILSM.KNIEEVADKLFVLVDGSYFYVSL...VSDKKEYEKIVDRHKAAAYDLLGI............................
A0A4R6IGQ8_9SPHI/80-196 .....................a-TLEDLQHTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKLKYKVILDSLRLGLATMIDQCNAAKLTSV.VDPQTTADFIFVLVDGAYFYLSL...ESDNRAYAERLDYYKQKAYEILGI............................
A0A1W2C6N9_9SPHI/80-196 .....................a-TIEDLQRTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKLKYRLILDALRKGLAVMIEQCNARSLTSI.DNPQVAADFIFVLVDGAYFYLSM...QSDGKAYLERLEYYKQKAYEVLSI............................
A0A1M7YEQ6_9DELT/83-199 ..................dpqq----RYRALLDLIF..SLQWSR.TVDP.GVH.FG..FYYQSFRDQRTLEHLREMFAWLRDYLEGQLKVFNEHGIIKV.GNPRMAADYIVTLMEGMEFHAQF...LAEDQPFENFAGGVKASVHQLL--ts..........................
A0A2D1U0C6_9SPHI/80-196 ....................vt--LSDLQKTIEMLF..SKKWNL.LFDD.GLF.YT..FYALAFREKKIKEKYKTILDSLRLALASMIDRCNEKQLIRV.EDAKTAADLIFVLVDGAYFYLSL...ESDKKAYAERLDYYKSKAYQILGI............................
A0A316B4W2_9BACT/81-197 .....................s-SSEVLLKMIDNLF..SKKWNT.LIDD.GLF.YS..CYSLTFRNKRIRGLYKDMLDRLRAELSQQISLCKEDGVLDV.EEPEEVADAIFVLVDGAYYYLSL...VDNKEEYEWKAARYKSQALSKL--rf..........................
A0A554VPX4_9FLAO/81-198 .....................d-SKEKLEEFIMLLF..SRKWND.YVDD.GLF.YS..FYAQVYRNKDFNKSFKSFLETLHNVLKNRLLDARNNGIIVN.TNIDELTEIIFALIDGAYYYLGT..fTDNRKEYEKQVTIYMNHVKQLIE-y...........................
A0A7Y9HTA0_9SPHI/81-196 ....................vl---SDLINTIETLF..SKKWNL.LFDD.GLF.YT..FYALAFREETIREKYKTILDSLRLALASMIEQCHTCNLINV.PDHQTASDLIFVLIDGAYFYLSL...EKDKEVYDQRLDYYKLKAYQILGI............................
A0A1M7ZAD2_9BACT/81-194 .....................q-NYTDPETFVNRLF..SRDWNL.LIDD.GVF.YS..CFSLIFRNETIKREFRNLHVKLREDLKEILDQ---DENLKE.KNTALLSEQIFVIVEGAYYYLSM...VEDQEEYEAKVIIFKNQVYQLLQ-p...........................
A0A1I0QWR0_9BACT/79-195 ....................tl--IEQLEEMLDNLF..STKWDT.LVSD.HVY.YS..CYTMIFRDPVVRKKYKQLHDSLRVSLKEQLAQAKAAGIISV.EDPEMTAKIIYTVLEGAYYYICM...EPSKQKRQEIMKQYKQHALQVLGM............................
A0A2K8XM28_9FLAO/80-197 ......................NSKENIERLIHSLF..SRSWNS.YFDD.GVF.YS..CYALIYRMKEFNESFKKYLEELHIILEKQLIEAKENNLIKN.DNIKEVTEIMYALIDGAYYYLGL..fEENDENYKNKVKLYQKYALSLLQ-f...........................
G0J6D3_CYCMS/81-194 .....................e-SSLDPILLVDRLF..SREWNL.LFDD.GVF.FS..CYAFIFRDTTIRNAYKKLHLKLRSTLKTILDK---DKDLSQ.KDTDLLAEKIFVVIEGAYYYLSM...IEEPKEYQRKLDIFKNQVLELIQM............................
A0A6J4XF13_9DELT/67-185 .....................d-SEAKLHFLINRLFedSRVLDKyLVGD.RAY.YE..CYALSITHSEVKAKFRQFYNRFQRSLAAELSNLLNANKLDA.KTSQLLADFLIVMLEGKDFYSNL...NEDEAALARLRGFLKHVSFQM---is..........................
#=GC seq_cons .....................p...ppLhphI-pLF..S+cWNp.LhDD.GlF.Yo..sYALsFRcccl+cca+plhcsLRphLpshlppspppsllpl.pssppsA-hIFsLl-GAYaYLuh...hs-pptYpc+hphaKppAhplLt.............................
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