#=GF ID   Tn7_TnsC_Int
#=GF AC   PF11426.12
#=GF DE   Tn7 transposition regulator TnsC
#=GF PI   Tn7_TnsC;
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF SE   pdb_1t0f
#=GF GA   24.30 24.30;
#=GF TC   25.50 26.20;
#=GF NC   24.20 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   15257292
#=GF RT   The carboxy-terminal portion of TnsC activates the Tn7
#=GF RT   transposase through a specific interaction with TnsA. 
#=GF RA   Ronning DR, Li Y, Perez ZN, Ross PD, Hickman AB, Craig NL, Dyda
#=GF RA   F; 
#=GF RL   EMBO J. 2004;23:2972-2981.
#=GF DR   INTERPRO; IPR021542;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   TnsC is a molecular switch that regulates transposition and
#=GF CC   interacts with TnsA which is a component of the transposase. The
#=GF CC   two proteins interact via the residues 504-555 on TnsC. The
#=GF CC   TnsA/TnsC interaction is very important in Tn7 transposition
#=GF CC   [1].
#=GF SQ   41
#=GS A0A485B5D0_KLUCR/192-238  AC A0A485B5D0.1
#=GS A0A0K1XFN7_9GAMM/508-554  AC A0A0K1XFN7.1
#=GS A0A269PUN2_9GAMM/452-497  AC A0A269PUN2.1
#=GS N8W4Y7_9GAMM/502-548      AC N8W4Y7.1
#=GS E6VVH2_PSEA9/500-545      AC E6VVH2.1
#=GS A0A143G7I3_9GAMM/506-552  AC A0A143G7I3.1
#=GS A0A1B7JUH2_9GAMM/505-550  AC A0A1B7JUH2.1
#=GS V5WK67_9SPIO/505-551      AC V5WK67.1
#=GS C4L8R5_TOLAT/506-552      AC C4L8R5.1
#=GS A0A3N9U4D8_9VIBR/502-543  AC A0A3N9U4D8.1
#=GS A0A3E0U2X8_9GAMM/510-555  AC A0A3E0U2X8.1
#=GS A0A1J4QKA2_9GAMM/505-550  AC A0A1J4QKA2.1
#=GS V2VHJ0_9GAMM/512-559      AC V2VHJ0.1
#=GS A0A346NMD1_9ALTE/505-550  AC A0A346NMD1.1
#=GS G0A4U3_METMM/506-549      AC G0A4U3.1
#=GS A0A2T5CDR2_9DELT/502-548  AC A0A2T5CDR2.1
#=GS A0A126T4K9_9GAMM/504-549  AC A0A126T4K9.1
#=GS A0A6N6N4K2_9DELT/506-550  AC A0A6N6N4K2.1
#=GS L8XV26_9GAMM/510-557      AC L8XV26.1
#=GS A0A166XH09_9GAMM/508-555  AC A0A166XH09.1
#=GS A0A1I1JHA4_9GAMM/509-555  AC A0A1I1JHA4.1
#=GS A0A0U4VSF5_9GAMM/502-546  AC A0A0U4VSF5.1
#=GS A0A4R5H3E1_9ALTE/503-549  AC A0A4R5H3E1.1
#=GS A0A0F4NKD6_9VIBR/505-551  AC A0A0F4NKD6.1
#=GS A0A1S1N4K9_9GAMM/508-555  AC A0A1S1N4K9.1
#=GS F9ZUI1_ACICS/504-550      AC F9ZUI1.1
#=GS Q5QZG6_IDILO/510-554      AC Q5QZG6.1
#=GS A0A1B7URY2_9GAMM/490-534  AC A0A1B7URY2.1
#=GS W9US66_9GAMM/504-550      AC W9US66.1
#=GS F7NQK2_9GAMM/502-546      AC F7NQK2.1
#=GS A0A4R2FDV0_9GAMM/506-552  AC A0A4R2FDV0.1
#=GS A0A0F4NZW9_PSEO7/508-555  AC A0A0F4NZW9.1
#=GS A0A1R4GWY0_9GAMM/512-559  AC A0A1R4GWY0.1
#=GS A0A432ZSQ4_9GAMM/510-554  AC A0A432ZSQ4.1
#=GS A0A5Q3S2B4_9NEIS/508-554  AC A0A5Q3S2B4.1
#=GS A0A2U3MUT5_9GAMM/512-559  AC A0A2U3MUT5.1
#=GS A0A1I3UWX9_9GAMM/504-548  AC A0A1I3UWX9.1
#=GS A0A317NXP2_9GAMM/504-550  AC A0A317NXP2.1
#=GS A0A1B2M3L2_9GAMM/507-554  AC A0A1B2M3L2.1
#=GS A3QJP4_SHELP/502-544      AC A3QJP4.1
#=GS A0A2C8F770_9DELT/508-553  AC A0A2C8F770.1
A0A485B5D0_KLUCR/192-238             .i-GQKEWHTLHSDDLRFKFSQCGK.G.N.LLYPAFK.KA.GLTFDVDDWLRR-m.....
A0A0K1XFN7_9GAMM/508-554             ..VKPSDWDSLPDTDLRYIYSQRQP.E.K.TMHERLK.GK.GVIVDMASLFKQ-a.....
A0A269PUN2_9GAMM/452-497             ..IPKKDWCKLPEDDLRYKFAMCEK.-.G.KFYQLLK.SN.GLVLSMQDLM---gnv...
N8W4Y7_9GAMM/502-548                 ..IKQSEWISLPSDDLRFKFSQKQK.S.Q.NFYDVLQ.SS.DLIFDTQTWVQS-m.....
E6VVH2_PSEA9/500-545                 ..IPRKDWHSLGSEDLRFVFSQTDS.-.K.DMYEHLK.QN.SMIFDMEDWLRK-p.....
A0A143G7I3_9GAMM/506-552             .l-KQDEWMSLPSDDLRFKFSQKEK.G.Q.DLYDILE.SS.NLIFDTQTWLQS-m.....
A0A1B7JUH2_9GAMM/505-550             ..VKQKDWHDLDVSDLRYQYAYCKE.E.RlSLVERLE.QN.GQMFDLDSW----aa....
V5WK67_9SPIO/505-551                 ..IHPKDWHTLETDDLRFVSSQADN.T.D.EFVEILK.SS.GVMFDTDAWIDTY......
C4L8R5_TOLAT/506-552                 ..IKSKDWDTLQTDSLRYMYSQNSA.P.T.AIYNEMV.KA.GYILKLSDILQKA......
A0A3N9U4D8_9VIBR/502-543             ..VKAKDWHSLESQDLRYLYAQKDQ.-.A.TMYQTVR.DH.GLVLDLQ------hp....
A0A3E0U2X8_9GAMM/510-555             ..INSKHWCELEKQDLRFQYAQCDG.-.K.DMHQTMR.CN.DLIFNMESWL---ldm...
A0A1J4QKA2_9GAMM/505-550             .m-KPSNWHTLPSEDLRFKFSQTEK.-.G.RLYDDLM.YG.KELFDVPSWLKKV......
V2VHJ0_9GAMM/512-559                 .l-KYDQWQTLDSVDLRFQFSQKEN.D.Q.SFYDHLKtQT.DLIFDISNWIKQV......
A0A346NMD1_9ALTE/505-550             ..VKSTSWHTLPSDDLRFKFSQAEK.-.G.RFYHELQ.YG.KELFDVPNWLKE-v.....
G0A4U3_METMM/506-549                 .v-SRKEWQSLKSDDLRYLYSESGG.-.S.EIYQALQ.QR.GLMFELEDW----av....
A0A2T5CDR2_9DELT/502-548             ..IKMKDWHTLDSRDLRFLRSQADT.E.D.KFQDSLN.RE.GIFFDTENWLRS-m.....
A0A126T4K9_9GAMM/504-549             ..VKLENWDSLADDDLRFIKSQKVS.A.K.AVHTALK.NK.GMLLEL-------rehfgk
A0A6N6N4K2_9DELT/506-550             .i-PKNKWHTLDSDDLRFMHSQAQS.-.-.STYEYFK.QN.SMIFDLEQWVS--nt....
L8XV26_9GAMM/510-557                 ..IKQKEWHTLDSDDLRFQFTQREE.G.E.PFYEYLR.DNtSLIFEIDDWLPK-v.....
A0A166XH09_9GAMM/508-555             ..IKLKDWHTLPSDDLRFGYSQHKK.QsG.ELYQYYK.QQ.GKIFDIESWLKQ-s.....
A0A1I1JHA4_9GAMM/509-555             ..IKKKDWCTLDSDDLRFEHSQTDN.N.D.TLYAVLK.CK.NGIFDVENWLMK-a.....
A0A0U4VSF5_9GAMM/502-546             .t-KPDQWDTLANDDLRYISSQQSS.A.T.CVHSALG.AK.GILFDLRKWV---s.....
A0A4R5H3E1_9ALTE/503-549             ..IKLKEWNTLSSNDLRFVFSQCES.A.D.EFHNKLI.KS.GVVLNIDNWMKK-t.....
A0A0F4NKD6_9VIBR/505-551             ..IKQTQWHTLDSEDLRFVHSQSDS.D.N.EVYTAMS.KS.GLILDIQSLLEK-v.....
A0A1S1N4K9_9GAMM/508-555             ..IKLKDWHTLPSDDLRFGYSQHKKqS.D.ELYQYYK.QQ.GKIFDMTAWLKQ-s.....
F9ZUI1_ACICS/504-550                 ..VKKEKWHALDSHDLRFLFSQASS.E.E.DVYKSLG.QK.GLFFDTESWVDSY......
Q5QZG6_IDILO/510-554                 ..IKSKEWHTLPSDDLRFKYSQRKS.-.-.QFYGELA.VG.RDIFDMEARLKQV......
A0A1B7URY2_9GAMM/490-534             ..IKRTQWLELPTNDLRYVYASSDK.-.N.NVYQLFK.EQ.GLIYDLKS-----vrdr..
W9US66_9GAMM/504-550                 .m-KKADWHTLDSEDLRFLFSQSAN.E.E.TFQESLG.CN.GLLFDAQDWVNS-f.....
F7NQK2_9GAMM/502-546                 .t-KPDQWDTLDWDDLRYISSQQSS.A.T.AVHSALG.AK.GLLFDLNKWV---g.....
A0A4R2FDV0_9GAMM/506-552             ..IKPSEWDQLPMDDLRFIKSQCKD.A.A.EVHAALE.KK.GMMFDLKSLL---iqt...
A0A0F4NZW9_PSEO7/508-555             ..IKPKDWHTLPSDDLRFGYSQHKK.QsG.ELYQYYK.QQ.GKIFDMTAWLKQ-s.....
A0A1R4GWY0_9GAMM/512-559             ..VKQKDWHTLDSDDLRFQFSQRDE.S.E.TFYEHLK.TNtSLIFDVDDWLPK-a.....
A0A432ZSQ4_9GAMM/510-554             ..IKSKEWHTLPPDDLRFKYSQRKS.-.-.QFYGELA.VG.RDIFDMEARLKQV......
A0A5Q3S2B4_9NEIS/508-554             ..VKPSDWDSLPDTDLRYIYSQRQP.E.K.TMHERLK.GK.GVIVDMASLFKQ-a.....
A0A2U3MUT5_9GAMM/512-559             .t-KPDQWQTLDTVDLRFQFSQKES.E.H.SFYEHLKaQT.NIVFDIDHWLKQV......
A0A1I3UWX9_9GAMM/504-548             ..IKMKEWHTLESDDLRFMHSQAAN.E.D.EMLDAAR.QS.GLVFNSDEWL---g.....
A0A317NXP2_9GAMM/504-550             .m-KKADWHTLDSEDLRFLFSQSAN.E.E.IFQESLG.CN.GLLFDAQDWVNS-f.....
A0A1B2M3L2_9GAMM/507-554             ..VKQDQWHTLDTEDLRFQFSQKDE.K.Q.NFYQHLK.EHtQLIFNMERWFEQ-v.....
A3QJP4_SHELP/502-544                 ..VKRTDWNTLESDDLRFIYSQVGK.S.E.SIYEALK.DN.GLVLDLK------kv....
A0A2C8F770_9DELT/508-553             vp--QKDWHTLESDDLRFMYSQADK.-.K.SLHAHLS.KN.SVIFNLEDWLNK-a.....
#=GC seq_cons                        ..lKtc-WcTLsS-DLRFhaSQpcp.t.p.phYptLc.ps.GllFDhpsWlpp.h.....
//