#=GF ID   Toxin_10
#=GF AC   PF05431.15
#=GF DE   Insecticidal Crystal Toxin, P42 
#=GF PI   Toxin_P42; Toxin_10; Toxin_10_; Toxin_10; Toxin_P42;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_19338 (release 8.0)
#=GF GA   28.60 28.60;
#=GF TC   28.60 28.60;
#=GF NC   28.50 28.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9500937
#=GF RT   Variants of the Bacillus sphaericus binary toxins: implications
#=GF RT   for differential toxicity of strains. 
#=GF RA   Humphreys MJ, Berry C; 
#=GF RL   J Invertebr Pathol 1998;71:184-185.
#=GF DR   INTERPRO; IPR008872;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Family of Bacillus insecticidal crystal toxins.  Strains of
#=GF CC   Bacillus that have this insecticidal activity use a binary toxin
#=GF CC   comprised of two proteins, P51 and P42 (this family).  Members
#=GF CC   of this family are highly conserved  between strains of
#=GF CC   different serotypes and phage groups [1].
#=GF SQ   64
#=GS A0A853BFP3_9ACTN/103-245  AC A0A853BFP3.1
#=GS A0A7D8UUW5_9HELO/250-389  AC A0A7D8UUW5.1
#=GS A0Q1D4_CLONN/205-321      AC A0Q1D4.1
#=GS A0A8H6AHF1_9HELO/286-433  AC A0A8H6AHF1.1
#=GS A0A4Z1IZR2_9HELO/242-389  AC A0A4Z1IZR2.1
#=GS A0A841H621_9BACT/350-486  AC A0A841H621.1
#=GS A0A8H4QHT2_9HELO/237-389  AC A0A8H4QHT2.1
#=GS A1BGH9_CHLPD/208-393      AC A1BGH9.1
#=GS A0A0F4JLZ2_9ACTN/1-161    AC A0A0F4JLZ2.1
#=GS A0A7G7BFS7_9ACTN/223-385  AC A0A7G7BFS7.1
#=GS K9PFX5_9CYAN/196-377      AC K9PFX5.1
#=GS A0A0D7CLB1_9ACTN/192-359  AC A0A0D7CLB1.1
#=GS N1PLB7_DOTSN/239-389      AC N1PLB7.1
#=GS A0A6I1MI71_9CLOT/147-291  AC A0A6I1MI71.1
#=GS A0A068TX63_COFCA/345-520  AC A0A068TX63.1
#=GS M7TX19_BOTF1/244-374      AC M7TX19.1
#=GS A0A175W4N0_9PEZI/242-393  AC A0A175W4N0.1
#=GS Q9FZ74_ARATH/208-379      AC Q9FZ74.1
#=GS A0A194WTD1_9HELO/232-373  AC A0A194WTD1.1
#=GS A0A0M9ZJZ9_9ACTN/192-359  AC A0A0M9ZJZ9.1
#=GS A0A5R8Z1W2_9ACTN/198-368  AC A0A5R8Z1W2.1
#=GS A0A164I1L2_9NOCA/244-370  AC A0A164I1L2.1
#=GS A0A6J0JV95_RAPSA/213-381  AC A0A6J0JV95.1
#=GS A0A2Z4UW71_9ACTN/268-430  AC A0A2Z4UW71.1
#=GS D9VKZ2_9ACTN/252-415      AC D9VKZ2.1
#=GS A0A078FTD8_BRANA/116-279  AC A0A078FTD8.1
#=GS A0A1M7Z6J4_9BACT/190-382  AC A0A1M7Z6J4.1
#=GS A0A4Q7PFE0_9FLAO/221-403  AC A0A4Q7PFE0.1
#=GS A0A0C5GK81_9ACTN/165-288  AC A0A0C5GK81.1
#=GS A0A384K0G6_BOTFB/174-319  AC A0A384K0G6.1
#=GS A0A4Z1H8V1_9HELO/242-391  AC A0A4Z1H8V1.1
#=GS A0A6G9YR14_9NOCA/286-413  AC A0A6G9YR14.1
#=GS A0A2Z2KHD0_9BACL/176-343  AC A0A2Z2KHD0.1
#=GS A0A124HDY9_9ACTN/206-373  AC A0A124HDY9.1
#=GS F4HQU1_ARATH/189-360      AC F4HQU1.1
#=GS A0A562HU15_MICOL/214-360  AC A0A562HU15.1
#=GS A0A1E5P178_9ACTN/199-369  AC A0A1E5P178.1
#=GS A0A7W7R9Z6_KITKI/144-269  AC A0A7W7R9Z6.1
#=GS A0A1B1AZ85_9ACTN/166-313  AC A0A1B1AZ85.1
#=GS A0A365H7E8_9ACTN/276-440  AC A0A365H7E8.1
#=GS A0A5Q0BKW2_9GAMM/197-346  AC A0A5Q0BKW2.1
#=GS E2Q428_STRCL/250-377      AC E2Q428.1
#=GS A0A2Z4W9D6_9CLOT/151-283  AC A0A2Z4W9D6.1
#=GS A0A397Y4J9_BRACM/212-376  AC A0A397Y4J9.1
#=GS A0A7G5LX44_9ACTN/169-313  AC A0A7G5LX44.1
#=GS A0A559J082_9BACL/207-370  AC A0A559J082.1
#=GS A0A1D8P5D8_9FLAO/190-380  AC A0A1D8P5D8.1
#=GS A0A0Q8YCG8_9MICO/248-398  AC A0A0Q8YCG8.1
#=GS Q0RIN8_FRAAA/263-408      AC Q0RIN8.1
#=GS A0A4Z1JFQ5_9HELO/282-428  AC A0A4Z1JFQ5.1
#=GS A0A1E7N8N1_KITAU/38-159   AC A0A1E7N8N1.1
#=GS G2YSK7_BOTF4/194-339      AC G2YSK7.1
#=GS A0A101NTF4_9ACTN/125-275  AC A0A101NTF4.1
#=GS E4ZP30_LEPMJ/238-382      AC E4ZP30.1
#=GS U9W0P1_9CYAN/171-342      AC U9W0P1.1
#=GS A0A6P6UZS6_COFAR/219-394  AC A0A6P6UZS6.1
#=GS A0A6J1D6P2_MOMCH/120-286  AC A0A6J1D6P2.1
#=GS A0A0A0KQZ6_CUCSA/209-374  AC A0A0A0KQZ6.1
#=GS A0A257JP26_9PROT/239-385  AC A0A257JP26.1
#=GS A0A2R8B5Y4_9RHOB/203-385  AC A0A2R8B5Y4.1
#=GS A0A3E2J8G4_9BACI/237-389  AC A0A3E2J8G4.1
#=GS V6JGH6_STRRC/193-359      AC V6JGH6.1
#=GS A0A2T6DPC7_9BACT/221-398  AC A0A2T6DPC7.1
#=GS A0A8J3FQY8_9ACTN/255-421  AC A0A8J3FQY8.1
A0A853BFP3_9ACTN/103-245             .................vidr----ETVVPCVAV-KDKTRSAA....WIVQNSPTYTLRRR.RSYSLV-........ASL.DLR.G..AKEGGKiT...KT....VGWG.ISKT....K....TD.AYTESVGVTVG............FEAG..V.EA.KG.....VGV..........KVTGSVTQTLg....yEQS.FS....N..T.EMFEQS....V--------...--....-.-.--.-........--....---------------..-.---.--.----------------gveggapagyvtamyaekhviyavr.......
A0A7D8UUW5_9HELO/250-389             .......tlpytaffdpehvp------------------SLTA....YKTTNNPFITVGRS.IAWYVE-........GVW.QND.T..DGNLKR.E...KL....MKYG.ISTT....D....ST.EITHSVGISIS............ATAG..I.GV.VE.....SSI..........TLNYQFTHTDt....hSFT.EY....S..E.RQ----....---------...--....-.-.--.-........--....---------------..-.---.--.----------------ttesndvpahtasvlfskhivikayrgeeks.
A0Q1D4_CLONN/205-321                 .................kiln----------------------....-------------N.SYWNLLT........EFS.NID.P..GSSATK.S...IT....ITSG.ITKT....E....ST.SLGLSIGSRVG............LEIG..LeSI.GK.....ISA..........ELSTQLSTSF......NTS.VS....I..T.QQ--IT....TTDTVEFKP...QP....R.T.QR.I........AT....YQFI-----------..-.---.--.----------------eqyeidaaqpl.....................
A0A8H6AHF1_9HELO/286-433             .................svvl--------PFIFY-LPNDSAWN....LARISKPFYTVTRE.IAWNVE-........GVW.NND.S..AGDFNR.S...KT....IKWG.ISKT....Q....SE.EMVHSAGVSVS............ASY-..-.GI.KG.....FES..........SVTLNY----......QFT.QT....T..S.KSFTEY....QEGETTESF...-V....V.P.GK.T........AK....VLF------------..-.---.--.----------------skhiwlkakagdgtmasqvemian........
A0A4Z1IZR2_9HELO/242-389             ..................csa------VLPFIFY-LPNDSAWN....LARISKPFYTVSRE.IAWHVE-........GVW.NND.S..PGDFNR.S...KT....IKWG.ISKT....Q....SE.EMVHSAGVSVS............AS--..Y.GI.KG.....FES..........SVTLNYQFTQ......TTS.KS....F..T.EYQEAE....TTESFVVPE...KA....V.K.VL.F........SK....HIWL-----------..-.---.--.----------------kakagdgtvasqvemva...............
A0A841H621_9BACT/350-486             ..................tlv------VVPYTAV--PADS-FT....QQAVLSPFYYVASE.PFWKCT-........--M.IVP.T..PAGGTL.T...VA....ESVG.MSQT....N....AS.SFAQTTSMTVG............AEFG..A.AY.GG.....VSV..........GVTVSMTEELr....lETS.TS....A..T.NSTEVV....TS-------...--....-.-.--.-........--....---------------..-.---.--.----------------vslnfpsqeitsvwqgqsliqvfrsd......
A0A8H4QHT2_9HELO/237-389             ....pftclfppndqpsidgi----------------------....----ANPFISVERW.GNWTLA-........LFD.NNT.T..GINQSS.S...TA....TTVG.ISQT....Q....TE.SFQHSTGIKIS............SEVG..I.--.--.....-EL..........VASVSVELNY......QFT.YT....S..S.SSIESL....RSETVTYNL...-T....T.L.PQ.H........AA....ALWVKHYAFRSVRSD..G.---.--.----------------siigpdlpfnlnvtsktqf.............
A1BGH9_CHLPD/208-393                 .....................VFVGETLIPFYMVGSDSACVGNnlrsWQINNRPYYCLKRE.QQWRLDP........KGI.INQ.P.dIAHRTE.K...IK....VSSG.IEQQ....S....GT.VMQKKTGFSVGmdf......gnkSEMG..V.TF.DG.....ITAk........tETTRAFKIQWq....nEVT.IT....T..T.ESTKIWe..tTERELIIDY...ET....V.S.GG.F........TY....IYWVLTDIWTLLSGE..-.DTS.DS.WEVMT-VLSQPTTFPK................................
A0A0F4JLZ2_9ACTN/1-161               ....................m-LVGSVLFPFPFIND-PVLSRA....RQGQENPYYVLKRY.GSWRNV-........YYY.EHS.G..ASAYTK.E...EE....VTVG.VTTS....N....TK.EVEHTAGVKLT............ATSE..F.SF.IG.....AST..........TLS----VVS......TTT.TS....T..S.E---NT....RKTTVRREY...-P....A.G.PR.R........AE....AIWYREDRFVLERLN..G.EHV.LE.WAVRNPDRVITDAYP-a...............................
A0A7G7BFS7_9ACTN/223-385             ...................rv------KVPCLAVKDTGR-SLI....WQLQNSPTYTLERR.SCYHREG........FIN.NKD.G..SIPQSR.S...SSwmtgVSEG.VTKE....W....SA.KVGVSVGFETG............VKAG..V.LF.AE.....ATA..........KFSANLSI--......EAG.YS....S..A.TRVEEM....KSHTDTVEL...-V....A.P.PH.H........SA....AMYGIQDELRMIRED..G.TVV.--.----------------ggqeggltfeqhds..................
K9PFX5_9CYAN/196-377                 ................vgkpf------LLPYFMV---NDNNPA....WQVQNSPYYLLSRE.VCYTLND.......qYFT.YNN.T..ASEQEY.E...VT....IRAG.FTTE....E....SE.NFSKTTGLEVAntleqtigakvgAETK..IpGF.GK.....VSGevs....setSFSLTASASL......SLG.YS....T..S.TSLSRH....NEQEIRRLV...-K....C.Q.PY.T........SL....AGWTQTSRFTLLRLD..G.SRL.KT.WEVLE-----------ggvfidd.........................
A0A0D7CLB1_9ACTN/192-359             .....................VLIGQAAVPFAVQ--DGGGSAA....DQSRNNPYLIIKRY.GYWDQV-........FFY.EHA.G..NSEHEE.I...KE....TTVG.LTKT....S....AT.EVERSTGISVT............AEAS..F.AY.KG.....FSA..........GLSSTVTNSL......KTT.YS....S..S.ESHEHW....VKDTIRRTY...AN....N.G.KR.V........SE....ALWYRGDRYVVQRMD..G.TAV.VE.WETRTKEFSVLDGFPQ................................
N1PLB7_DOTSN/239-389                 ..................asv------ALPYTVFFDPSDTRSV....NKIA-DPFVSISRS.CCWHVG-........GVW.RNG.G..EGPFER.T...LT....IEYG.ISEE....K....SK.SLTESAGVSIT............QDIG..V.SA.GP.....FSS..........SVSMSLNYQ-......-MT.TA....S..S.HSRTEF....SNKTVTEKF...-T....V.P.AM.T........AT....AAFTRRMFYRSVRGD..G.SEV.V-.----------------advgi...........................
A0A6I1MI71_9CLOT/147-291             ...............lyhdna----------------------....----------IERT.TYWKLI-........DTI.DLP.A..GSSHTL.N...KK....YSVG.INKN....E....QL.NIGQALGIKLItgae....vsggADCK..F.AS.AK.....ILA..........KLNGELNRTV......SKT.FE....N..S.RKINSV....FESNTNISY...NV....S.N.ED.K........VV....LRYQLVDNFKVDSET..-.---.--.----------------fknatskleslmnts.................
A0A068TX63_COFCA/345-520             ....................l-VVGKWYCPFMFV-REGTIMRR....YQMSNSMFYVMTLE.QQWKKI-........FSC.SNS.D.kEDNEGK.Q...LT....VDVV.LENE....AvyvgGF.KAEWDEGIVDE............GAIW..F.GFsDG.....GGA..........KRRVGLSPEI......VER.MK....W..E.QEREGWr.sgKNRQVRITR...AQ....E.F.KK.S........DEwrefGLYVLVERFVLRRMD..G.TLV.ME.YHFL------------hddqik..........................
M7TX19_BOTF1/244-374                 ..tlplrcffwsedarcltqi----------------------....----AKPFITISKG.IAWYVE-........GVW.ENG.G..EGTFTR.E...KR....IKCG.ISQT....Q....TE.SMEHTVGISIT............ASHG..F.KF.AE.....MSV..........TLNYQFTHTR......STS.FT....E..F.TETEVV....---------...--....-.-.--.-........--....---------------..-.---.--.----------------esfevpaktctvlfskhiylkgs.........
A0A175W4N0_9PEZI/242-393             ................nvvtl--------PFTSFFDDNDRASL....DNI-QDPFCAVTKA.VSWVVLE........KFP.NYQ.S..TS-YQQ.T...HS....VTTG.IRKT....E....SE.TTEHQTGIKIS............SEVG..Y.GL.SK.....WSI..........SLNYQF----......--T.FS....Q..T.SSVEEV....QERTMTKTI...T-....V.A.PR.T........--....---------------..-.---.--.----------------vaiawgkrvtiqgvrsdgsrisgeisfnvsee
Q9FZ74_ARATH/208-379                 .....................VVVGKWYVPFLFV--KEGGDAN....DQMNKSMYYSMTLQ.QRFEEV-........FFC.ENI.G..NNKHFE.VvvdVE....VETE.VVKL....E....GD.KIARETK-GVN............SDGV..V.WF.SV.....SGT..........QKIGLGSVVL......ERM.KW....E..E.ERFGWS....KKDELRSSI...KR....T.E.K-.FegggphwkSY....RCYVLVETFELKRTD..G.SLV.LT.YEF-------------khvdklks........................
A0A194WTD1_9HELO/232-373             ..................rsv------VIPFTCV-FPANDQTS....VDLIFNPFISIEQW.GNWTLA-........LFD.NNT.V..SVKQSS.S...QE....ITTG.ITNS....Q....TE.TFEHSTGVKIS............AEVG..V.E-.--.....---..........-LVGKVTTELy....yQFT.YT....T..S.ASTETL....RSQTITHTL...-T....T.P.PQ.H........AA....ALWVKHLAYRAV---..-.---.--.----------------rladgsi.........................
A0A0M9ZJZ9_9ACTN/192-359             .....................VLIGQTAVPFAVQ--DGGGSAG....DQSQNNPYLVIKRY.GYWEQV-........FFY.EHA.G..NSEHEE.V...KE....TTVG.LTKT....S....AT.EVERFTGISVT............AEAS..F.AY.KG.....FSA..........GLSSTVTSSL......KTT.YS....S..S.ETHEHW....VKDTIRRTY...AN....N.G.RR.V........SE....ALWYRGDKYVAQRMD..G.SPV.VE.WETRTKEFSVLDGWPQ................................
A0A5R8Z1W2_9ACTN/198-368             ....................i-LIGQAAIPYLAINE-PGKDTT....WQAKHSPYYIVRRY.GYWQQV-........LYH.EHA.G..NSTYTK.T...EE....AYIG.LTTR....N....EQ.VVEETTDIRVG............LDLS..F.SY.KG.....FST..........AVSSSYEHEL......KVT.TT....S..Q.EIKEQW....KKVTVSREF...KN....D.G.KR.V........AL....CVWYRGDHYTVHRIDsaE.TLI.AD.WRTLTETGHIDDGWPK................................
A0A164I1L2_9NOCA/244-370             ...................vv------TVPCTVV-TDPGKTIA....WQVANSPFYTLQRR.VNYSLQ-........IFR.NNQnG..STPAES.S...VS....VTTG.VTET....A....SE.EFSKRTSVTVT............AKAG..I.EV.KG.....LSA..........GVETSVTTEL......---.--....-..-.------....---------...--....-.-.--.-........--....---------------..-.---.--.----------------gyssryevaqlrsvtkthglttppqasga...
A0A6J0JV95_RAPSA/213-381             .....................VLVGKWYVPFIFV---KEGNVK....VQLKSSTYYNMTLY.QKWEEV-........YSC.QNA.DkkNREVVV.N...VE....VEPE.VVKL....G....GQ.GIEKET-IRVD............ENGVvwF.GV.AN.....VSV..........GLMSAVTERM......KWE.EErfgwK..S.DSQRAV....VKRSDKFDG...-G....G.S.NW.K........SY....KCYVLVESFVLRRMD..E.SVV.LT.FEFK------------hadksksk........................
A0A2Z4UW71_9ACTN/268-430             ..................nav------WVPFTAITDTAKS-TP....WKLENSPFYKLERK.AAWSLV-........RHL.NNN.T..QIVQKV.T...EA....VTLG.VEKE....Q....VS.SFTAAVGVAFT............ATAG..V.SS.GF.....ASA..........EVSTTYSLEL......GFG.TS....T..-.-GLKEI....ESRQVTKEL...-S....A.P.PG.T........AA....AVWVGSSTIQVVRAD..N.TRV.G-.----------------ppvtfkgetdhydqypd...............
D9VKZ2_9ACTN/252-415                 .................tvna-----VWVPFMAV-KDDDKSAS....WKLTNSPFYRIERR.ASWFMH-........RFI.NNT.T..STAQSV.S...ET....VTVG.VERE....R....SD.TFSAEVGISVS............SQVG..V.SS.GI.....ASA..........SVTTTYSLAL......--G.YS....S..S.TATKNL....EHKAVTHTL...TA....-.P.PN.K........AA....AMWVGDHTIQVTRQD..G.THV.--.----------------gtpltfhgdsahfdefp...............
A0A078FTD8_BRANA/116-279             ....................v-AVGNWYVPFIFV---KDGDAK....DQLKSTTYYSMTLY.QKWEEV-........YSC.ENA.YkeNREVLV.N...VE....VEPE.VVKL....E....GQ.VIGKET-IRVDe..........nGVVW..F.GF.AN.....KSV..........GLRSVVTERM......KWE.EE....R.fG.WKSRAV....VERTDIFDG...GG....-.S.SW.K........SY....KCYVLVESFVLRRMD..E.SVV.LT.FEF-------------khadklk.........................
A0A1M7Z6J4_9BACT/190-382             ................ktisv-----EAIPASLINDNKYRTKS....DQIALSPYYYLTHE.KLWSSEQl.....nqVLI.SDY.L..TSEISE.E...--....IISS.FKFD....S....YK.SIEKTFGTTFDasinl..ygkksAEMG..V.EE.GG.....ASAtatnevgatlNLAYQFKDQTtl..ldTET.RS....Q..E.ENIKKA....IKFTYKKPE...KD....D.E.KD.F........YL....RFWLIVDRYILEDSK..G.NEI.GR.WDHTNE----------knfkvqk.........................
A0A4Q7PFE0_9FLAO/221-403             ....................t-FISETLIPYALVKNDAGFPPN....IQVQRSPYYKIERT.QFYQLPQavgdtqtqPDQ.IYR.P..GETITR.T...IK....VKAG.VKQS....K....VT.EIFRKINVAFTsg........qeISAN..I.PK.TP.....ISL..........KSTRSLSSAF......ELS.EK....T..I.TSLEETy..eKEESISTTF...-E....V.P.ET.L........RA....VHYVLVDRYRLKRLD..G.TVI.LQ.WDVKT-KIKHVATYP-e...............................
A0A0C5GK81_9ACTN/165-288             ..................gva----------------------....----------VTRE.QFWHCTG........DSY.SLA.P..GESREV.S...YT....VTHG.MQDS....S....SQ.S--DTTNASVG............VSAS..A.GW.GP.....FSA..........SVSASLSESS......TTS.Q-....-..Q.LTVSTQ....TTSYVSTTF...-H....N.L.SR.V........PEm..nLFWQLTDIATVYDKD..G.R--.--.----------------plssv...........................
A0A384K0G6_BOTFB/174-319             ...vlpftafypiddersldl----------------------....---IRNPFCVISRS.IAWHCE-........AAW.VND.T..NGPFDR.Q...VT....IKYG.VSKT....Q....SE.SMEHSIGVEVS............ASSG..I.GL.VE.....FSV..........NLNYQFTYNS......SSS.FT....E..F.RESE--....VIEKINIPP...RN....A.T.VL.F........SK....HIWI-----------..-.---.--.----------------kgvradssqvisqveita..............
A0A4Z1H8V1_9HELO/242-391             ..................csa------VLPFIFY-LPNDSAWN....LARISKPFYTVTRE.IAWNVE-........GVW.NND.S..AGDFNR.S...KT....IKWG.ISKT....Q....SE.EMVHSAGVSVS............ASY-..-.GI.KG.....FES..........SVTLNY----......QFT.QT....T..S.KSFTEY....QEGETTESF...-V....V.P.GK.T........AK....VLFS-----------..-.---.--.----------------khvwlkakagdgtiasqvemvann........
A0A6G9YR14_9NOCA/286-413             ..................rav------TVPCTVV-TDPGKTIA....WQIANSPFYTLERR.VNYSLQI........FRN.NQN.G..TTPAES.S...VS....VTTG.VTET....A....SE.EYSKRTSVTVT............AKAG..I.EI.KG.....LSA..........GIETSVTTEL......---.--....-..-.------....---------...--....-.-.--.-........--....---------------..-.---.--.----------------gyssryevaqlrsvtkthglttppqasga...
A0A2Z2KHD0_9BACL/176-343             ............ytlatciav--------------DDPHYNDQ....QKIKTNPYYLYVKK.QYWKKV-........--E.SHV.L..APKESY.K...YT....MTSG.MTQE....D....QN.TVSKTVSHTIG............VDAG..F.QF.GKegrfnVAA..........SLSYQYTEQL......ETT.VS....H..T.TIQMTE....--TTQEHSI..iND....E.N.YN.V........AW....SKYILVSEYSVQRSD..G.TLVsKP.WTVTDHNTTQSSYYP-l...............................
A0A124HDY9_9ACTN/206-373             ...................ve--VGAMAYPFPLV-RDPAYDRR....RQAQDNPYYILRRY.GFWERV-........YSY.EHG.G..ASDYTH.T...EE....TTVG.LTTT....N....AR.TVEETTSISVT............AEAS..F.GF.KG.....VGA..........SLSTTISHEL......KVT.TT....H..E.EVKSHS....KKVTIERNY...-Q....A.G.KR.V........TE....AIWYRSDKYVLERLN..G.TVV.LD.WTTRDPNTSVADAYP-l...............................
F4HQU1_ARATH/189-360                 .....................VVVGKWYVPFLFV--KEGGDAN....DQMNKSMYYSMTLQ.QRFEEV-........FFC.ENI.G..NNKHFE.VvvdVE....VETE.VVKL....E....GD.KIARETK-GVN............SDGV..V.WF.SV.....SGT..........QKIGLGSVVL......ERM.KW....E..E.ERFGWS....KKDELRSSI...KR....T.E.K-.FegggphwkSY....RCYVLVETFELKRTD..G.SLV.LT.YEF-------------khvdklks........................
A0A562HU15_MICOL/214-360             ..................rav------VVPCTLI-KHPGKDVA....WQVARSPFYTLERR.VSFYCHK........HYD.NSQ.G..SVEESA.P...QV....VTTG.VSKT....K....SD.EFSQRTSVSVT............ASAG..I.AA.KG.....FSA..........SVETSFSIEL......GYT.SR....V..D.VTQFSE....VQET-----...--....-.-.--.-........--....---------------..-.---.--.----------------wpmtvppkksaamwsprheiiaidkdgntvg.
A0A1E5P178_9ACTN/199-369             ...................qi--AGEVAVPYFLIADDHGHDAQ....WQGQHSPYYIIRRW.SSWNKV-........QWR.VHP.A..LNTEVH.S...WS....TTEG.TTEE....A....AA.DVDRTLNLSVT............AEAS..F.GI.KG.....FSA..........SVSTTIETGL......SVK.TS....K..K.WSRSYS....KLVNGSYTV...GP....A.E.AD.L........AV....GDWFRQDKYCIYRAQ..GgGDI.LE.FTVTHPGTRVSRTY--mr..............................
A0A7W7R9Z6_KITKI/144-269             ................hnghf----------------------....----------VTRE.QFWQRLP........ESY.SLA.A..GEDKTV.N...YT....QTQG.MQAS....S....SD.T--KTVTGSVS............ASAG..G.GW.GP.....FSA..........SVNASLSKSS......TRT.QQ....V..T.VSTETTn..fTSNQYTNDT...--....A.H.GR.I........C-....LFWQLMDILTVFDGT..G.T--.--.----------------plasv...........................
A0A1B1AZ85_9ACTN/166-313             ..................ivr-------VPFTGVNDEG-RDLQ....WKVLNSPFYRLHRR.VGYNRAI........FTN.NQH.G..TQPARA.S...EQ....VVTG.VVQS....E....SE.AWTTLTRIVVS............ASAG..I.AF.KG.....LSV..........GADVNITR--......ETG.YE....K..R.TSLTEF....TESTRTQEM...-V....T.P.PQ.A........SG....VLWVKSHELQLYRVD..G.SAV.--.----------------aga.............................
A0A365H7E8_9ACTN/276-440             ..................iiv---ASVWMPYTAVKDTA-RTDA....WKFANSPFYQVQRT.AAWRRL-........QYL.NND.T..GRDQPL.S...DV....VTVG.WEKG....Q....TH.GWSVNVGFEIS............TTNS..L.GT.GP.....VSA..........STTFKFTAAF......GAT.--....G..S.YSAKES....SSHTKSRTF...-T....V.P.SN.H........AG....AMWVGHEKLRIVRAD..N.TIV.G-.----------------stlscdtelfaydqyp................
A0A5Q0BKW2_9GAMM/197-346             ..................vlr-------LPFFMI-KDDERDSA....WKARNSPWYYLRRQ.VKFISKE.......gWFI.YNN.T..STEQER.S...WK....TTKG.WSKT....D....SQ.SFSITTGMSVS............ASAS..F.FG.TG.....VTT..........EF----SMEL......--G.YS....T..E.SSFTET....YTEETEIKI...-K....A.P.AK.T........SV....VMWQGQSTFTLLRSD..G.SEA.GR.W---------------vrndd...........................
E2Q428_STRCL/250-377                 ...................ht-----VIVPCSVV-KDVGLTAG....QQVDQTPFYTLERRvSYYCQM-........HYD.NTT.G..PVQQTN.E...QT....VTTG.VSKT....K....SE.EFSTRTSIGIS............RTAG..I.SM.QG.....MEA..........SQTLNFSIEFg....ySVR.YD....N..T.QFEENS....NK-------...--....-.-.--.-........--....---------------..-.---.--.----------------wslsvppktaas....................
A0A2Z4W9D6_9CLOT/151-283             ...................na----------------------....----------VQRT.TYWKLI-........DAI.DLP.A..GSTHTL.T...KK....YTSG.ITKN....E....EL.KMGQTLGLKLVsevs....gsigGECS..F.AS.AK.....IMA..........SLTGELNKTA......SKS.FT....N..N.QEIKST....FESNTNISY...QA....S.N.ID.K........VI....LRYQLVDNYKVD---..-.---.--.----------------pntfknattd......................
A0A397Y4J9_BRACM/212-376             ....................v-AVGNWYVPFIFV---KDGDAK....DQLKSSTYYRMTLY.QKWEEV-........YSC.ESA.YkeNREVLV.N...VE....VEPE.VVKL....E....GQ.VIGKET-IRVDe..........nGVVW..F.GF.AN.....KSV..........GLRSVVTERM......KW-.--....-..E.EERFGW....KSRAVAERR...DRfdggG.S.SW.K........SY....KCYVLVESFVLRRMD..E.SVV.LT.FEF-------------khadrlkt........................
A0A7G5LX44_9ACTN/169-313             .........lvnfapdatsis----------------------....--MGQSPKYVVVHE.QYWQLGG........VTC.SLA.P..QEKRSL.S...FL....RTVGrLDST....T....SQeQVQSSFNTSVS............ASAS..W.GW.GS.....LSA..........SVSASLSSSS......STS.QT....T..TiTSTETT....V---VNQSV...EN....K.GtEP.V........TI....LEWQLVDRFTVVSTE..-.---.--.----------------rppavme.........................
A0A559J082_9BACL/207-370             ....................a-VVGATLLPFIVV-QDNQASDY....TKINTSPYYVLVKE.EYWEKT-........--F.SAV.V..PAGLTY.N...YS....FTSG.VSSE....D....QR.TLTDTLSITVG............ADFG..F.AF.KA.....ITA..........SLKTEITKSL......QTT.VS....S..T.TSK--A....TEETISSSV...TN...pS.G.IT.T........GY....TGYQLVTKYTLKRTD..G.TLV.QEpWIVKNNKITI------ark.............................
A0A1D8P5D8_9FLAO/190-380             ....................k-VISKEAIPASLIKDEDYRTKS....DQIKISPYYYLKRE.KFWSSKR........LPI.ITL.S.kQNKTEV.S...EE....YTSS.FTST....D....YQ.SVEKVIGHTFNasiev..ygkktTEVG..V.QD.SG.....LSAsq......knEVGGSLKLAYqf..qdQTT.TL....NqkT.QSKEEN....IKKTLKKTYrqlDS....N.E.GD.I........RL....RHWVPVDRYTLTNSR..G.KII.GQ.WEHT------------dpnqithq........................
A0A0Q8YCG8_9MICO/248-398             .................tssl--------PWFAVNDPDYPAL-....QSMVKSPTYRLERT.DKWALDD........AFW.FND.E..SESITR.E...LQ....VTVG.VNGS....S....AT.SFASETGIELG............FEY-..-.--.-G.....FSK..........LVKGSVKLSQ......KFT.YT....T..S.SSNGWS....SETSKKTTY...-V....V.P.PM.T........AI....AMYVLNSTYSLYRQD..G.SQV.N-.----------------tdsagynv........................
Q0RIN8_FRAAA/263-408                 ..................rav------IVPCTLV-KDPNKTIA....WQVANSPFYTLERR.VNYTLQI........FRN.NEA.G..TVPQPS.N...RR....VTTG.VSKE....R....SE.EYSRKTSVTVS............ASAG..I.SI.KA.....FSA..........SIDTSVTTELgyssryGVT.QF....T..E.DSKD--....---------...--....-.-.--.-........--....---------------..-.---.--.----------------hglitpprssgalwsatheviairkdgdav..
A0A4Z1JFQ5_9HELO/282-428             ..................csa------VLPFIFY-LPNDSAWN....LARISKPFYTVSRE.IAWNVE-........GVW.NND.S..AGDFTR.S...KT....IKWG.ISKT....Q....SE.EMVHSAGVSVS............ASY-..-.GI.KG.....FES..........SVTLNYQFTQ......TTS.KS....F..T.EYQEGE....TTESFVVPG...KT....V.K.VL.F........SK....HIW------------..-.---.--.----------------lkakagdgtmasqvemv...............
A0A1E7N8N1_KITAU/38-159              ..................gva----------------------....----------VTRE.QFWHSTG........ESY.SLA.P..GETRTV.N...YS....VTQG.MQES....S....SE.S--ETTNASVG............VSAS..A.GW.GP.....FSA..........SVSASLSESS......ITT.QQ....L..T.VSTQTT....--TFVSTTY...LN....L.S.KHpE........LN....LFWQLTDVATVYDEN..-.---.--.----------------glpla...........................
G2YSK7_BOTF4/194-339                 ...vlpftafypidderslnl----------------------....---IRNPFCVISRS.IAWHCE-........AAW.VND.T..NGPFDR.Q...VT....IKYG.VSKT....Q....SE.SMEHSIGVEVS............ASSG..I.GL.VE.....FSV..........NLNYQFTYNS......SSS.FT....E..F.RESE--....VIEKINIPP...RN....A.T.VL.F........SK....HIWI-----------..-.---.--.----------------kgvradssqvisqveita..............
A0A101NTF4_9ACTN/125-275             ..................ivr-------VPFTGVNDEG-RDLQ....WKVLNSPFYRLHRR.VGYNRAI........FTN.NQH.G..TQPARA.S...EQ....VVTG.VVQS....E....SE.AWTTLTRIVVS............ASAG..I.AF.KG.....LSV..........GADVNITR--......ETG.YE....K..R.TSLTEF....TESTRTQEM...-V....T.P.PQ.A........SG....VLWVKSHELQLYRVD..G.SAV.AE.----------------alsf............................
E4ZP30_LEPMJ/238-382                 evklpficlfpptdrpsidri----------------------....----DNPFCSIQRW.GSWSLS-........MWD.DNT.T..SRDQDS.S...TS....TTVG.VSDS....Q....SE.EFSHSAGIKIT............SGAG..I.SV.GV.....FNA..........--SGSYELNY......QFT.YT....S..S.TSRELL....SSKTVTRNL...KT....P.P.GK.-........AC....ALWVRHFVFRSVRAD..G.---.--.----------------snig............................
U9W0P1_9CYAN/171-342                 .....................KLIGEALIPAVFVNDTAYSDHR....YQILQNPYYVLRRE.QYWDRSQg.....rgIYY.QHD.G..QREVEK.T...FS....IEFG.ISEK....T....SQ.KIEDTFGWKLS............ASGK..F.GF.DK.....SSI..........ALAGSLSRSI......KTT.TT....N..E.TEIKAS....KKETYKEKI...--....S.E.KK.F........AY....AQYALVDHYRLFDKH..K.NVV.RE.WEIVLYKTTMSDGFD-a...............................
A0A6P6UZS6_COFAR/219-394             ....................l-VVGKWYCPFMFV-REGTIMRR....YQMSNSMFYVMTLE.QQWKKI-........FSC.SNS.N.kEDNEGK.Q...LT....VDVV.LENE....AvyvgGF.KAEWDEGIVDE............GAIW..F.GFsDG.....GGA..........KRRVGLSPEI......VER.MK....W..E.QEREGWr.sgKNRQVRITR...AQ....E.F.KK.S........DEwrefGLYVLVERFVLRRMD..G.TLV.ME.YHFL------------hddqik..........................
A0A6J1D6P2_MOMCH/120-286             .....................VVVGKWYCPFIFV---RDGEVG....SQVSNSPYYEMTLQ.QNWEEI-........FGC.GNL.G..GGERGV.D...FD....VSVE.RE-V....I....SI.AGQRADGREVG...........dGVVW..F.GS.RG.....VGL..........SLAIEERVKWe...deRAGfEF....G..K.EKEEKY....VKMNRREDF...GG....V.E.EW.R........RF....GCYVLVERFVLKRMD..G.SLV.LT.WEFRH-----------thqirtk.........................
A0A0A0KQZ6_CUCSA/209-374             ....................i-VVGKWYCPFIFV---REGDVD....SQIKNSPYYEMTLQ.QNWVEV-........FGCgNNS.G..GRGVEL.D...VL....VEKE.VVSV....A....GR.VV---AGVNIG............DGAA..-.WF.GS.....SRV..........GLSMAIVERIk....wEEE.KG....G..F.EWVREGgekeVKVKRREEF...EG....V.G.MW.R........RF....GCYVLVERFELRRMD..G.TLV.LS.WEFRH-----------tnqirtk.........................
A0A257JP26_9PROT/239-385             ...rvtlpftclfdrndrpsl----------------------....DKI-ANPFCVIERW.TYWSLV-........LFN.NNT.T..SLPQSQ.S...KS....TMVG.ITET....E....SK.SFSHSVGVKVG............WEGG..V.GV.KW.....---..........----KVELNY......QFT.LT....T..S.TSTAVM....RSDTVQRTL...-T....S.P.PG.H........AA....ALWAQSWRFEVIRSD..G.S--.--.----------------riapglafet......................
A0A2R8B5Y4_9RHOB/203-385             ....................e-LISTEFLPAALVDDPSYQNLV....LQNRDVPFYRLERR.RYWELPN........DAY.THI.R.aNSTIAK.V...RS....VSTS.FEKSrfdeQ....TS.TIAFRAGYSGT............IQGK..A.AV.PN.....VGE.........vSASHTLSASFek..tdQTR.KG....S..S.EKSAGS....ESDTITVSF...PN....AlQ.ED.T........LW....VTWRLVDEYTLYRGP..E.SDE.VV.W---------------skpvtvpsrvffdafp................
A0A3E2J8G4_9BACI/237-389             ..................ldr----EVIIPMTSV-NDNEFPVS....WRLQNSPFYYMQRE.NLYNLI-........AFQ.DNE.T..SDKATL.K...YE....YKSG.IDKE....N....SK.SWSQKTGIEVS............AESG..I.SL.FG.....AEG..........KISCTVSVEL......--G.FE....G..S.SSIREF....TEETISSEV...-P....V.A.SK.T........AV....AIWSSSYNLKVLRGD..R.SQV.--.----------------gppltf..........................
V6JGH6_STRRC/193-359                 .....................VLIGQLAVPFFTI---GDSSPQ....WQVDNSPYYILKRY.GYWQKV-........FFY.EHP.G..TSKVTK.T...KK....VTVG.LTTS....T....GK.TVEETTGISVT............AEAS..F.AY.KG.....FSA..........SLSTTYSREL......KVT.TY....T..G.EVHEHS....TEETIEREY...QA....D.G.VR.V........AE....CLWYRGDRYTVERMD..G.TKV.LE.WNTLNPAVEVLDGYR-g...............................
A0A2T6DPC7_9BACT/221-398             ....................y-LIGIDVLPSVFINDPTYGNKV....DQALMNPYYYLERV.RKWKKV-........KEW.TYA.L..GQKQTL.T...QA....VHHG.SSCT....D....LR.TVETTVGVVVTakvsgeggqaapSEKG..G.AN.WK.....VAG..........ELSAQYSWQR......RDL.EQ....R..E.SKHEEY....IDQTETIEF...-T....P.I.QA.C........RL....VLWQVIDEYTLRNSR..LvTVT.PP.WSVFTDRI--------ewdv............................
A0A8J3FQY8_9ACTN/255-421             ..................rav------TVPYVMV-NDSNRTEE....WKVDNSPFYKILRK.RQYDLL-........RHV.DFR.G..GGGGEI.E...EA....ITVG.VTKE....R....SD.EFAVTTGITVGvst......gveVSAK..P.LG.MG.....ASA..........SVETSVSASL......ELG.YA....R..R.YGVSEF....DDHTLTVTY...-E....V.P.AD.H........AG....ALWTDTHQLVPVRGD..G.TLV.TN.EN--------------lklnagssss......................
#=GC seq_cons                        ....................h......hlPhhhl...sttsht.....phtpsPaYhlpRp.ttWphh.........hhh.sps.s..ssstsp.s...hp....lssG.lsps....p....up.shpcssGlsVs............ussu..h.uh.ts.....hos..........slssshohph......pho.hs....p..p.pphpth....pppshphsh....s....s....t.h........sh....hhahh.pph.l.c.p..t.p......................t...h...........................
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