#=GF ID   Tsp45I
#=GF AC   PF06300.16
#=GF DE   Tsp45I type II restriction enzyme
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_12151 (release 9.0)
#=GF GA   25.00 25.00;
#=GF TC   30.40 36.40;
#=GF NC   23.50 23.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0236
#=GF RN   [1]
#=GF RM   9427549
#=GF RT   The Tsp45I restriction-modification system is plasmid-borne
#=GF RT   within its thermophilic host. 
#=GF RA   Wayne J, Holden M, Xu SY; 
#=GF RL   Gene 1997;202:83-88.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR010443;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several type II restriction enzymes.
#=GF SQ   33
#=GS A0A191TP07_9BACT/2-260   AC A0A191TP07.1
#=GS A0A2N3IIZ2_9BACT/2-260   AC A0A2N3IIZ2.1
#=GS E7NW21_TREPH/2-39        AC E7NW21.1
#=GS F2NSE4_TRES6/2-261       AC F2NSE4.1
#=GS A0A420DVF2_9FLAO/15-276  AC A0A420DVF2.1
#=GS R7EYX5_9BACT/2-261       AC R7EYX5.1
#=GS A0A6S4QHD4_9SPIR/2-260   AC A0A6S4QHD4.1
#=GS A0A143XWT5_9BACT/3-260   AC A0A143XWT5.1
#=GS R9SHT7_9EURY/7-269       AC R9SHT7.1
#=GS A0A0F2IX60_9BACT/2-108   AC A0A0F2IX60.1
#=GS A0A0F2IWH4_9BACT/2-76    AC A0A0F2IWH4.1
#=GS A0A388TGC3_9BACT/2-260   AC A0A388TGC3.1
#=GS A0A3D8I8I4_9HELI/2-260   AC A0A3D8I8I4.1
#=GS A0A097ST24_9BACT/8-283   AC A0A097ST24.1
#=GS A0A4R2N6L3_9PAST/1-108   AC A0A4R2N6L3.1
#=GS A0A3D8IWQ4_9HELI/1-62    AC A0A3D8IWQ4.1
#=GS A0A4U8UAT9_9HELI/2-261   AC A0A4U8UAT9.1
#=GS A0A7D4QGK2_9SPHI/14-275  AC A0A7D4QGK2.1
#=GS A0A218ZSM5_9ARCH/2-262   AC A0A218ZSM5.1
#=GS G5GI10_9FIRM/2-266       AC G5GI10.1
#=GS A0A1T4PM72_9SPIR/2-273   AC A0A1T4PM72.1
#=GS T1DVQ5_9HELI/2-195       AC T1DVQ5.1
#=GS A0A4R6VE51_9PAST/2-265   AC A0A4R6VE51.1
#=GS A0A482ZZX9_9BACT/2-258   AC A0A482ZZX9.1
#=GS A0A3D8I0G9_9HELI/2-261   AC A0A3D8I0G9.1
#=GS V9HMU8_9NEIS/2-265       AC V9HMU8.1
#=GS A0A377R0T3_9NEIS/2-265   AC A0A377R0T3.1
#=GS A0A4P2VEL3_9ARCH/1-240   AC A0A4P2VEL3.1
#=GS A0A166AMT9_9EURY/2-259   AC A0A166AMT9.1
#=GS A0A4R2N6D4_9PAST/1-98    AC A0A4R2N6D4.1
#=GS A0A376BN77_9NEIS/2-265   AC A0A376BN77.1
#=GS A0A1W6LNU9_9BACT/2-259   AC A0A1W6LNU9.1
#=GS A0A1M7TD07_9DELT/2-260   AC A0A1M7TD07.1
A0A191TP07_9BACT/2-260              ...................................................NYWTELSIEYANQRSYLDDLFQVYPTIPEGIRDIDKERWTNIEKAFKKKNN...DILIRELLKL........EL..FPIKDSYIAYLKR.DA...SAIERNPKTINRICGRL.YEMGLDKIF..E..RCSEPKETNRQIGPFFRRWTNSKALG.IQP.V.G.L.EEF....TK.TK.NDAI.LNGSDKQLMDFAAEELNYKH..--TKGLDFIGRFNGKYVIGEAKFLTDFGGHQNAQFNDAISTVQA...K...NV...K...AI-KIAILDGVL..Y.IKG.......NNKMYKDITTt.yKDLN.I.MSSLVLREFLYQI................................
A0A2N3IIZ2_9BACT/2-260              ...................................................NYWTELSIEYANQKSYLDDLFQVYPTIPEGIREINQTIWKKVEQAFESQDN...ISLIRELLKL........DL..FPIKDSYIAFLKR.DS...SAIERNPKTINRICGRL.YEMGLEKIF..E..KCTEPKETNRQIGPLFRRWLNKRTLG.IQP.V.G.L.DKF....IS.SD.EDAI.LEGSDQELANFARNVLNYQR..--EKGLDFVARFNKQYIIGESKFLTDFGGHQNAQFADAIATLQT...P...NV...N...AI-KIAILDGVL..Y.IKG.......ENKMYKELTTk.yKNYN.I.MSALVLREFLYQL................................
E7NW21_TREPH/2-39                   ...................................................NRWTELSIEYANQRNYLDHLFRVYPTIPEGLRDIDG---------------...----------........--..-------------.--...-----------------.---------..-..--------------------------.---.-.-.-.---....--.--.----.--------------------..--------------------------------------------...-...--...-...------------..-.---.......----------...----.-.-------------qr..............................
F2NSE4_TRES6/2-261                  ...................................................NIWIQRSIELANNKNYLDKLFDVYPMIPNKIRKIDETYWDSIVQAFNNKDD...ICLIKYLLYL........DL..FPIKDSYIPFLRR.DT..aNALKNNPETVKRLCNRL.YKMGLDKIR..E..KCTEPKETNRQIGPLFKKWCKNSFDK.TKL.L.S.V.TDF....EK.TN.ENAI.LDATDKEMMDWAFRTVNYKR..--NKGLDFAGRFNGKYLIGEAKFLSDFGGHQDAQLEDAVLTLTA...P...NV...K...AT-KIAILDGVC..W.LKT.......NNKMYKAITEe.yCEEN.I.MSALLLKDFIKSL................................
A0A420DVF2_9FLAO/15-276             ...................................................NEWVFKSLELFENTPYLDNILEVYPLQTARPERLDSQLRRRIISAHQGRRT...QELIDILKNE........IK..FPYDEP-LWYLIK.NI..qGCLTNNPQQIERIAESL.YAMTAEETV..I..RLESAPKLNTQMGPMFTNWLRNNF--.-NL.L.E.I.DDF....RNsTN.GIFI.LDASEIVAKSFINNELNQNL..--AKRPDLVAKVNETYVIGEAKWIGSPGGNQNKQVIEVIDLCK-...N...QR...G...NVIRVGIIDGFS..W.AVHksnggiiNDKTCVQVQE...CEYD.I.VSALLLTQYLESL................................
R7EYX5_9BACT/2-261                  ...................................................NYYTRLSIELATQRDYLDQLFKVYPLAPDTIRSINETLWDNIEDSYRQNDN...DRLIRTLLKL........KL..FPVKDSYVSFLRH.DK...DAIERNPQTVNRICGRI.KELGLEKLY..E..RITEPKEPNRQIGPLFRRWIYSGALG.LNP.V.A.E.KTF....LS.NN.DNAI.LSGSDSILKKFAAEKLNFKR..DDDKGFDLICRFNQKYVIGEAKFITDEGGHQNGQFQDALKILKI...H...SK...P...NIIKIAILDGVL..Y.IPG.......KKKMYNAITS...ENIN.V.MSALLLRNFLYSL................................
A0A6S4QHD4_9SPIR/2-260              ...................................................NEWIKLSIEYANKKSYLDDLFDVYPIISGSTRSIDETIRNEIKKHFAAKND...NELIRSLLKL........EL..FPIKDSYIAYLRN.DK...TAIDRNPQTIKRLCKEL.YEMGLDKIF..E..RCSAPKETNRQIGPMFRNWIKKGSLK.IKP.V.K.L.EKF....IE.ND.EDAI.LDASDRGMKDFARQKLGYNH..--DKGLDFVGRFNKKYVIGEAKFLTDFGGHQKAQFNDAIRTIKA...E...GV...K...AI-KIAILDGVL..F.IKN.......HNEMHKLIIEe.yKNEN.I.LSVLLLHKFLNQ-l...............................
A0A143XWT5_9BACT/3-260              ................................................rsl----QQSIEYANQRSYLDDLFKIYPTIPEGLREIDGKLWIKVEESFDKKDN...VNLIRNLLKL........KL..FPIKDSYIAYLRR.NP...SAIERNPNTVNRIAGRI.YELGIDKLY..Q..RCSEPKETNRQIGPMFKSWINSGVLG.MNP.V.P.M.DEF....LA.SD.ANAV.LRASDDKMKAFAAQYLNYRH..--NKGLDFVARFNGKYVIGEAKFLSDFGGHQNAQFNDAIGTVTA...E...GV...D...AV-KIAILDGVL..Y.IRG.......NNKMYTAITGk.yRDLN.I.MSALVLREFLYQL................................
R9SHT7_9EURY/7-269                  ...................................................NYWTKLSIEYANQKSYLDDLFKVYPTIPNGIRDIDNKIWENIKTSFNNQNN...KKLIENLLKL........DL..FPIKDSYIAYLRK.DK...TAIDRNPETIDRLAGRI.YDMGIDEVY..K..QCTKPKETNRQIGPMFKEWVNKGVLG.KKP.I.E.I.DEF....IN.TE.NNAI.LSGSDQEMEEFAEDYCDYEYagNTKKGLDFIARFNKKYVIGEAKFLTDIGGHQNAQFNDALNVLDS...N...VS...E...KVTKIAILDGVL..Y.IKN......eRTKMYRTTVQ...KNDN.I.MSALILNEFLYSI................................
A0A0F2IX60_9BACT/2-108              .............................................kpkgks---------------------------------------------------...----------........--..-------------.--...-----------------.---------..-..--------------------------.---.-.-.-.NKF....IL.NN.DDAV.LDASDNAMMEFAKNNLGYTH..--NKGLDFVARFNNQYIIGETKFLTDFGGHQNAQFNDAISTVEA...K...GV...N...AI-KIAILDGVL..Y.IKS.......NNKMYKAIT-...----.-.-------------................................
A0A0F2IWH4_9BACT/2-76               ...................................................NHWINLSIDYANQRSYLDDLFQVYPTIPEGIRDIDNNLWKQVEKAFEKKDN...FELLESILKL........DL..FPN----------.--...-----------------.---------..-..--------------------------.---.-.-.-.---....--.--.----.--------------------..--------------------------------------------...-...--...-...------------..-.---.......----------...----.-.-------------rlcqmkihm.......................
A0A388TGC3_9BACT/2-260              ..................................................g-YWADLSIEFANQRNYLDELFKIYPTIPDGIRDIDKNQWQRIEDSFTARNN...ISLITHLLQL........DL..FPIKDSYVAYLKR.DP...DAIQRNPNTINRLCGRL.YEMGLDKIF..E..KCSEPKETNRQIGPLFKRWLTNGGLG.IKP.I.G.I.NDF....QK.NK.KNAV.LDASDAEMKDWCSRYLHYSR..--DKGLDFVGRFNGKYVIGEAKFLTDFGGHQNAQFADAISTITS...S...SV...Q...AI-TIAILDGVS..Y.IKT.......NNKMYRDITTt.ySNCN.I.MSALVLREFLYSI................................
A0A3D8I8I4_9HELI/2-260              ...................................................NYFLYSSIELANQRDYLDQLFRVYPMSPDNIRTIDSTLWERFESAFGEDNQ...TQIIESLLDF........DL..FPIKDSYIAYLRR.DR...SAIHRNPATIARICGRL.KDMGINKIY..E..NLSTPKETNRQIGPLFKRWVNSGVLG.LEP.I.N.I.EEF....KH.TQ.SNAI.LKASDSVMQSFAKEYLGYTN..--DKGLDFIARFNGKFIIGEAKFLSDFGGHQNAQLNDALTLLNT...P...LR...D...DIIKVAILDGVC..Y.IKN.......KSKMFHTLHQ..ySQNN.I.LSALLLRDFLYQI................................
A0A097ST24_9BACT/8-283              eylrksvenkesldsrymslkmhkslnemvettkqikellitiktlnknni-------------------------------------------------SS...EKIYSELKEL........VLneLGNKSEFNCFINA.CDsaiSTIKSNPETLKSIVNLYlQYRDISEYTpkEwiQAMIDKGAQRSLGIIGQQKVIDIAIQ.IGF.VfS.E.NND....IF.FN.NPYS.VAYYSKKLKQIIIPGINFGS..-QSKDLDVIFKVNEYYIFLEAKHIKESGGAQDKQIKELIELLNI...D...LP...K...NIFLISYLDGVYsnY.L--.......----------...----.-.-------------ldltdqeiinpeaikqqnlkskvlqqryeiil
A0A4R2N6L3_9PAST/1-108              ...................................................---------------------------------------------------...----------........--..-------------.--...-----------------.---------..-..--------------------------.---.-.-.-.---....--.--.----.-------MSDFAKEFLGYGH..--DKGLDFIAKFNDTYIIAETKFLTDFGGHQNAQFNDAISTMKS...QlsqTD...K...KVKAISILDGVL..Y.ING.......NHKMMKALCSf.dDSEV.V.ISSVLLRDYLYQL................................
A0A3D8IWQ4_9HELI/1-62               ................................................mli--------------------------SPNNIREIDSIKWDRLKKVFSVDEQ...EKIIESLLDF........DF..FPIKDFCIAYLRG.DK...SVIK-------------.---------..-..--------------------------.---.-.-.-.---....--.--.----.--------------------..--------------------------------------------...-...--...-...------------..-.---.......----------...----.-.-------------fyy.............................
A0A4U8UAT9_9HELI/2-261              ...................................................NHFLTQSIELANQRDYLDQLFRVYPMSPDNIREIDSTKWQRFEQAFAENKQ...NEIIESLLDF........EL..FPIKDSYIVYLRR.DK...NAIERNPLTIARICGRL.KEMGLNKIY..E..NLSQPKETNRQIGPLFKRWVNSGALG.LES.V.G.I.NDF....LH.TR.DNAI.LNASDSVMKHYAKEYLGYER..--EKGLDFIARFNGKIIISEAKFLTDFGGHQNAQLEDALQLLKC...P...LK...E...KVVKIAILDGVC..Y.IQN.......KSKMNAMLCQk.yGDEN.I.LSALLLRDFLYSL................................
A0A7D4QGK2_9SPHI/14-275             ...................................................NPWIKKSLDLFNNNNYLDQILEIYPFQIAVPTRLNKELSREIMMAHAARDT...PKLFSLLKNL........TK..FPYDDPIWYLLKS.VK...GCFDNNPRQVQRIADSL.YSMTAEEVV..V..RLESAPKINTQMGPMFTKWLKNR---.YKS.L.H.A.DEF....MN.SD.TGIVnLHASEEEAKRFVNDVLK--Q..DLPKRPDLFVKVNSTYIIGEAKWIGQPGGNQEKQVGEVVQFC-S...K...QR...G...SVIRIGIVDGFP..WaIHNlsg.rliNNKEAVNIQE...SPYN.I.ISALLLDEYL---ggf.............................
A0A218ZSM5_9ARCH/2-262              ...................................................NSWAQRSIDIANNGNYLDQLKAIYRIDIPGMRDIDPELVREIAIAHSKKDA...RNVFIKSLDL........PV..FPIEHPYVAFIRY.DP..dKFIKLNPQVVEYIGNAI.LALRIDEIL..L..LGAKAKRPVKRYGQAFKSWLLSLPYR.KLD.I.-.-.PQFstvsLG.SN.EIVI.CDESDQEYEDFANSQLRCGL..--VKAPDLLLRKGDKYILGEAKFLSDLGGGQDRNFSDAMDMVNN...H...NG...N...AH-RIAVLDGPL..W.LNG......pDRNQTRGVRN...TNAD.V.MSALVLQDFIS--hf..............................
G5GI10_9FIRM/2-266                  ...................................................NIWTKKSIELANQRNYLDLLFKIYPMSVNLRRELSSKTISEITNYFNNKDS...KKLLNLLLSQ........NI..FPIKDSYVAYLKR.DK...SAIDRNPNTVSRITGIL.YEMGLDEIF..N..KTTAPKETNRQIGPLFKNWIDTGALG.CKI.TtS.E.NEF....LK.AK.KNMV.FNGTDSNMKFFANKYLGYDR..--NKGLDFLAKFNNTYILAEAKFLTDFGGHQNAQFVDAISTMESkfrN...TN...N...KVKTIDILDGVL..Y.IKS.......RNKMYTMISEnfgDDDI.I.ISAVLLRDYLYSI................................
A0A1T4PM72_9SPIR/2-273              ...................................................NIWTQRSIELANQHDYLDQLFKVYPLSANEKRDLSNDVVEKLKALLQTRDS...KGLINLLLDQvkgngdekHP..FPIKYSYVSYLKN.DR...SAIERNPKTVERIASYL.YEMGLAGIL..E..KTSAPKETNRQMGQLFKNYIDQATLG.LKV.T.KdE.MSF....LN.SE.EDII.FNCSDSQGEDFAKRVLGYQR..--DKGLDFIAKVKETYIIGETKFLTDFGGHQNAQLNDAIDTLTS...S...IQ...StsfHVKKIAILDGVC..Y.IKS.......GSKMYKEITSf.sDDTV.V.LSATLLREFLGSL................................
T1DVQ5_9HELI/2-195                  .................................................ts--WTRESINLANNYDYLDRLYTIYPVISNVRRNLSPEVMNNLASMLLPTPNfarGELLNLLLEQ........EV..FPIKDSYVAYLRR.DR...TAIERNPNTVNRIETTI.ANMGYQNVL..R..EITRPIEANRQMGQHFKNWVNSQYFRyEKT.N.D.I.NHF....LT.TD.TLLV.FIGSDKVMAEVAQDYFGYQA..V-------------------------------------------...-...--...-...------------..-.---.......----------...----.-.-------------vnpvylsftsrnfsskliaqi...........
A0A4R6VE51_9PAST/2-265              ...................................................NIWTIKSIELASQQNYLDLLYKVYPMSVNLRREIDQTTKNKIRIFLENKDK...KNLLLTLLEQ........EV..FPIKDSYIAYLKK.DK...SAIDRNPNTVDRIFGIL.VDMGFDEII..D..KATAPKETNRQIGPLFKRWINTGALG.AEV.T.NdF.ERF....LK.RD.GNII.FNSSDDAMKKYAGQYLGYDH..--EKGLDFIAKFNHTYILAETKFLTDFGGHQNAQFNDAISTMKS...A...LKktdK...NVKIISILDGVL..Y.IKG.......NHKMMKELRSf.dDNEI.V.ISSVLLRDYLYHL................................
A0A482ZZX9_9BACT/2-258              ...................................................NHWTKLSIEFASQRNYLDELFSVYPTIPEGIRDIDKNLWQQVEQSFQAKNN...IDLLNILLKM........DL..FPIKDSYVAYLKR.DN...GSISRNPNTVDRLCGRL.YEMGLDKIF..E..RCSEPKETNRQIGPLFKRWLNNGVLG.IIP.V.T.I.EEF....SN.SK.NNAI.LDASDAQMMEFAKQHLGYKH..--NKGLDFVARFNGVYVIGEAKFLTDFGGHQNAQFNDAMTTVKS...N...VN...A...V--TVAILDGVP..Y.IDS.......TNKMCKAVRK..qSKHN.I.MSALILRDFLYSL................................
A0A3D8I0G9_9HELI/2-261              ...................................................NCFLKSSIELANQKDYLDQLFRVYPMSPDNIREIDSIKWDRFEKAFSVNEQ...EKIIESLLDF........DL..FPIKDSYIAYLRR.DK...SAIKRNPATIARICGRL.KEMGLNKIY..E..NLSQPKETNRQIGPLFKRWVNSGILG.IQP.V.S.L.EVF....KN.TN.ENAI.LNASDSAMQEFAKEHLGYTR..--LKGLDFIARFNGKMILGEAKFLSDFGGHQNAQLEDAISLLNT...S...LT...P...NIIKVAILDGVC..Y.IQG.......KNKMFETLTKg.yQNHN.I.LSALLLRDFLYQ-v...............................
V9HMU8_9NEIS/2-265                  ...................................................NLWTQRSIDLAAQSNYLDQLYRVYPMSVNLRRELAEQTQTDIRTHLENRDG...RNLLEVLLKQ........EI..FPIKDSYVAYLKR.DK...TALERNPGTVSHLAGIL.IEMGFDEIL..D..KTTVPKETNRQIGPLFKNWINSGALG.VPV.TnD.A.DEF....LN.YQ.GNIV.FNAGDKAMEYFAKTHLGYQH..--NKGLDFIAKFNQTIIIGEAKFLTDFGGHQNAQFNDTIATMKSvlaA...SQ...Y...TVKTIAILDGVL..Y.IKG.......KNKMFSDLATf.aDDEV.I.ISAVLLRDYLFSV................................
A0A377R0T3_9NEIS/2-265              ...................................................NLWTQKSIDLASQSNYLDQLYRVYPMSVNLRRELSESTQNEIRTYLNNKDG...KNLLNVLLKQ........EI..FPIKDSYVAYLKR.DK...TAIERNPATVSRLAGML.IEMGFDEIL..D..KTTVPKETNRQIGPLFKNWISSGALG.IPVtT.N.V.EEF....LN.YQ.GNIV.FNAGDAAMQALAKEYLGYRH..--NKGLDFIAKFNHQFIIGEAKFLTDFGGHQNAQFNDAVITMRS...QlakTD...H...SVKTIAILDGVL..Y.IKG.......KNKMFSDLNNf.kDNEV.V.ISAVLLRDYLFSV................................
A0A4P2VEL3_9ARCH/1-240              .................................................ms---------------------KIYTPTKEEKRTINYDVENRIKQAYENKNK...MALIKELLKL........EK..FPIKDPYIAFLRKgDE...TFLERNPETVERISSKL.LSMDFDELI..R..LSEEPKEFNRQLGPMFKNWLKK--LG.YPF.L.V.E.DQF....TN.FRgGIAF.LDGSDKKLGKFANEKLKCGL..--DKTPDFIAKVDDKFVIGEAKFLTDFGGHQDRQFEDALKLIRN...K...QC...K...AI-RVAVLDGVL..W.LNT.......DNRISRDVRQ..lKDDE.IaLSALLLEEFLKSL................................
A0A166AMT9_9EURY/2-259              ...................................................NYWTKLSVDYASQKSYLDDLFQIYPTIPEGIRDIDNELWKDVETSFKLRDN...INLIKNLLKL........EL..FPIKDSYVAFLRK.YP...KSIDLNPKTINRLSSRL.YEMGLNEIF..N..KSTEPKETNRQMGPKFQNWINKGFLG.FDL.V.N.S.DEF....LK.SK.DDAI.LKGSDLQLQNFAEEHLNYTS..--NKGLDFIGRFNNEYVIAEAKFLTDFGGHQNAQFRDATALLND...D...SV...N...AI-RIAILDGVL..Y.IKG.......KNKMYKYIEK...NDDKiI.LSSLLLREFLYSI................................
A0A4R2N6D4_9PAST/1-98               ................................................msv----------------------------NLRREINHSTQENIKNYLQSGDK...TNLILTLLEQ........EM..FPIKDSYIAYLKR.DR...AAIDRNPKTIDRIFGIL.VDMGFDEII..D..KATVPKETNRQIGPLFKR--------.---.-.-.-.---....--.--.----.--------------------..--------------------------------------------...-...--...-...------------..-.---.......----------...----.-.-------------................................
A0A376BN77_9NEIS/2-265              ...................................................NIWTQKSIELATQSNYLDQLYRIYPMSVNLRRELSQQTQDEIRTYLDKKDG...KNLLNVLLKQ........EI..FPIKDSYVAYLKR.DK...TAIERNPATVSRLAGML.IEMGFDEIL..D..KTTVPKETNRQIGPMFKNWLASGALG.VPV.T.D.NpDKF....LN.HQ.GNIV.FNAGDAAMAYFAQTHLGYQH..--NKGLDFIAKFNQTIIIGEAKFLSDFGGHQNAQFNDAIATLRA...PllaNR...Y...NVKTIAILDGVL..Y.IKS.......NNKMFNEISGf.aDDDV.V.VSAVLLRDYLFSV................................
A0A1W6LNU9_9BACT/2-259              ...................................................NRYLELSIEYANQRSYLDDLYSVYPTIPEGIRNIDKQAWGKVEAAFNKGNN...YELIKRLLEF........DL..FPIKDSYVAYLRR.DK...SSLERNPKTINRLSGRL.YEMGLDLIY..Q..KCSEAKETNRQIGPMFRKWAASKSLG.LKP.C.S.L.EQF....VS.NN.EDAV.LEGSDVQLMRFAKEHLGYNH..--NKGLDLVARFNGKYVIGEAKFLTDFGGHQNSQFRDALATLDA...E...VD...A...V--AVAVLDGVL..Y.IRG.......KNKMYTELTEi.sAEKN.I.MSALLLREFLYSL................................
A0A1M7TD07_9DELT/2-260              ...................................................NYWTNLSIEYANQKSYLDDLFQIYPTIPDGIRDINTVYWNDIEGAFDNKDN...KRLITALLQL........DL..FPIKDSYIAYLKR.DK...SSIERNPKTINRICGRL.YEMGISKIY..E..RCSEPKETNRQIGPMFRNWLKKKSLG.IQP.V.C.S.ETF....LS.NQ.NDAI.LDAGDSELMKFAKEHLGYNH..--NKGLDFIARFNKKYVIGEAKFLTDFGGHQNAQFNDAINTIKA...D...GV...N...AI-KIAILDGVL..F.IKG.......NNKMYKEITTt.yKTYN.I.MSALVLREFLYQL................................
#=GC seq_cons                       ...................................................NhWhphSIEhAsQpsYLDpLaplYPh.ssshR-Ispphhpclcpsappccs...tpLlptLLch........-l..FPIKDSYlAYL++.Dc...suI-RNPpTlsRlsutL.h-MGh-cIh..c..+sotPKETNRQIGPhF+pWlpstsLG.hps.h.s...pcF....hp.sp.pshl.lsuSDpthtpFApphLsYp+....sKGLDFlu+FNtpYlIGEAKFLoDFGGHQNAQFpDAlshlps...p........p...sl.pIAILDGVh..Y.Ics.......psKMhptlpp...ps.s.l.hSAllL+-aLhpl................................
//