#=GF ID TxDE
#=GF AC PF18711.5
#=GF DE Toxoflavin-degrading enzyme
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF08265
#=GF GA 25.00 25.00;
#=GF TC 25.50 25.70;
#=GF NC 24.00 24.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP Domain
#=GF CL CL0104
#=GF RN [1]
#=GF RM 21166463
#=GF RT Toxoflavin lyase requires a novel 1-His-2-carboxylate facial
#=GF RT triad.
#=GF RA Fenwick MK, Philmus B, Begley TP, Ealick SE;
#=GF RL Biochemistry. 2011;50:1091-1100.
#=GF RN [2]
#=GF RM 21799856
#=GF RT Structural and functional analysis of phytotoxin
#=GF RT toxoflavin-degrading enzyme.
#=GF RA Jung WS, Lee J, Kim MI, Ma J, Nagamatsu T, Goo E, Kim H, Hwang
#=GF RA I, Han J, Rhee S;
#=GF RL PLoS One. 2011;6:e22443.
#=GF DR INTERPRO; IPR040553;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in toxoflavin-degrading enzymes such as
#=GF CC toxoflavin lyase (TflA) also known as toxoflavin-degrading
#=GF CC enzyme (TxDE). TflA/TxDE is structurally similar to the vicinal
#=GF CC oxygen chelate superfamily of metalloenzymes, despite the lack
#=GF CC of apparent sequence identity [1, 2].
#=GF SQ 69
#=GS A0A3S2U7S2_9BACI/135-189 AC A0A3S2U7S2.1
#=GS Q4A0M3_STAS1/129-183 AC Q4A0M3.1
#=GS A0A248TKC8_9BACI/134-189 AC A0A248TKC8.1
#=GS A0A0A2UQH5_9BACI/135-189 AC A0A0A2UQH5.1
#=GS A0A2I0QTA8_9BACI/135-189 AC A0A2I0QTA8.1
#=GS A0A143HBW0_9BACL/134-189 AC A0A143HBW0.1
#=GS A0A3N5ZV37_9BACL/134-189 AC A0A3N5ZV37.1
#=GS A0A1H9X2G9_9BACI/130-182 AC A0A1H9X2G9.1
#=GS W4ESI8_9BACL/138-192 AC W4ESI8.1
#=GS A0A380BLM9_SPOPA/135-189 AC A0A380BLM9.1
#=GS A0A431WEL4_9BACI/135-189 AC A0A431WEL4.1
#=GS A0A511Z5K6_9BACL/130-182 AC A0A511Z5K6.1
#=GS M7NBT6_9BACL/137-188 AC M7NBT6.1
#=GS A0A365KSB3_9BACL/130-182 AC A0A365KSB3.1
#=GS A0A2U3ALH2_9BACL/138-192 AC A0A2U3ALH2.1
#=GS A0A1Q2L4G1_9BACL/130-182 AC A0A1Q2L4G1.1
#=GS A0A5J6PMF7_9BACI/137-192 AC A0A5J6PMF7.1
#=GS A0A1I6AC97_9BACI/130-182 AC A0A1I6AC97.1
#=GS A0A4Q4IDD2_9BACL/134-186 AC A0A4Q4IDD2.1
#=GS A0A3P5XLC5_9BACL/130-182 AC A0A3P5XLC5.1
#=GS F2F3L6_SOLSS/1-52 AC F2F3L6.1
#=GS A0A0M1NU26_9BACI/135-189 AC A0A0M1NU26.1
#=GS A0A3D8YVC1_9BACL/135-189 AC A0A3D8YVC1.1
#=GS A0A859FJC7_9BACI/135-189 AC A0A859FJC7.1
#=GS A0A6B3W4Z8_9BACI/135-189 AC A0A6B3W4Z8.1
#=GS A0A4V1W9R6_9BACL/89-141 AC A0A4V1W9R6.1
#=GS A0A2C0Z9D9_9BACI/135-186 AC A0A2C0Z9D9.1
#=GS A0A5J6PQQ3_9BACI/130-182 AC A0A5J6PQQ3.1
#=GS A0A2N0Z4B6_9BACI/137-192 AC A0A2N0Z4B6.1
#=GS A0A0J1IMB8_NIACI/136-190 AC A0A0J1IMB8.1
#=GS V6J0E9_9BACL/134-186 AC V6J0E9.1
#=GS A0A127VXT0_SPOPS/135-189 AC A0A127VXT0.1
#=GS A0A3M8HGG2_9BACI/136-190 AC A0A3M8HGG2.1
#=GS A0A6G1X549_9BACI/135-187 AC A0A6G1X549.1
#=GS C4L1W6_EXISA/136-190 AC C4L1W6.1
#=GS A0A0N0S3W5_9BACI/136-190 AC A0A0N0S3W5.1
#=GS A0A264W1A9_9BACL/138-192 AC A0A264W1A9.1
#=GS A0A0Q3RXB5_9BACI/130-182 AC A0A0Q3RXB5.1
#=GS A0A0M1NYT6_9BACI/136-190 AC A0A0M1NYT6.1
#=GS A0A1H1DZQ3_9BACI/136-190 AC A0A1H1DZQ3.1
#=GS A0A371S750_9BACI/134-188 AC A0A371S750.1
#=GS A0A0J6FY76_9BACI/136-190 AC A0A0J6FY76.1
#=GS B1YFD6_EXIS2/136-190 AC B1YFD6.1
#=GS A0A2V3WC79_9BACI/135-189 AC A0A2V3WC79.1
#=GS A0A1S2QQA5_9BACI/135-189 AC A0A1S2QQA5.1
#=GS A0A127VY77_SPOPS/135-189 AC A0A127VY77.1
#=GS A0A1G8WQF1_9BACI/179-233 AC A0A1G8WQF1.1
#=GS A0A0A8JMJ5_BACSX/130-182 AC A0A0A8JMJ5.1
#=GS A0A1V2S978_9BACI/135-189 AC A0A1V2S978.1
#=GS A0A2S1H2S8_9BACI/135-189 AC A0A2S1H2S8.1
#=GS A0A3M8P667_9BACL/130-182 AC A0A3M8P667.1
#=GS A0A1C0Y6L2_9BACL/134-189 AC A0A1C0Y6L2.1
#=GS A0A1G7YX56_9BACL/130-182 AC A0A1G7YX56.1
#=GS A0A2S5GE08_9BACL/120-171 AC A0A2S5GE08.1
#=GS A0A221MCP6_9BACI/135-189 AC A0A221MCP6.1
#=GS A0A0W7YDT6_9BACI/136-190 AC A0A0W7YDT6.1
#=GS A0A6L6GZT7_9BACL/130-182 AC A0A6L6GZT7.1
#=GS A0A098EP74_9BACL/138-190 AC A0A098EP74.1
#=GS I8UKG5_9BACI/135-189 AC I8UKG5.1
#=GS A0A5J6STP3_9BACI/130-182 AC A0A5J6STP3.1
#=GS A0A1H3ZG03_9BACI/134-188 AC A0A1H3ZG03.1
#=GS A0A0B4R8I9_9BACL/130-182 AC A0A0B4R8I9.1
#=GS A0A0C2S510_9BACL/133-184 AC A0A0C2S510.1
#=GS D5DUW9_PRIM1/135-186 AC D5DUW9.1
#=GS A0A2D1SSE4_9BACL/135-189 AC A0A2D1SSE4.1
#=GS A0A0M0GL48_9BACI/135-190 AC A0A0M0GL48.1
#=GS A0A0A3IBU7_9BACI/134-189 AC A0A0A3IBU7.1
#=GS A0A345PE69_9BACI/135-189 AC A0A345PE69.1
#=GS A0A0A3HX98_9BACL/136-190 AC A0A0A3HX98.1
A0A3S2U7S2_9BACI/135-189 .ISEIGLIVEDAVNIGNIMIQNKIYERDKKTI.SNH.YLNFMGIKSKGIFVILAQPGR
Q4A0M3_STAS1/129-183 .ISEIGFVCNETNAIYQALSDYKIETFEHAHF.EPY.ALNFLGDTSDESYILLTPEDR
A0A248TKC8_9BACI/134-189 .ISEVGIATNHIIELAQQLQDKGIPVRNNESIkHQK.YLNFFGEYDDGVYIIVAPVGR
A0A0A2UQH5_9BACI/135-189 .ISEISITVTDAQSAGVRMGQIGIHERDQEPI.SGS.VLNFMGSRKRGNSLLLIEPGR
A0A2I0QTA8_9BACI/135-189 .ISEISLVVDDALSVGKEMQAIGVKRRIDKEV.ESG.VLNFMGEPDNDSFVLLLEEGR
A0A143HBW0_9BACL/134-189 m-SEISLVVKDKVQAAKQLRGLSIVERDGEEVtNDN.TLSFMTKGALPVYLLLVNPKR
A0A3N5ZV37_9BACL/134-189 .ISEIGLTSQDIKKNIEKIQKLGISSKNNEPIsYDQ.YLNFMGEYEDGVYIIVAPVGR
A0A1H9X2G9_9BACI/130-182 l-SEVSITTPFVQEVGEQIQDIGVHVSGHVGI.EGN.ELNFLGSN--DTFILLVPPNR
W4ESI8_9BACL/138-192 .ISEINVTTDDVLKVGNELQKIGITLTDEEPL.ESN.ALNFLGEREDGAFFLLAPTKR
A0A380BLM9_SPOPA/135-189 .ISEIGLIVKDAPMVGEQLKEINIFDSDNDPV.TNS.SLNFMQDNNDGVFIILTSVDR
A0A431WEL4_9BACI/135-189 .ISEIGLTVDDAIDTCNRLMEIGIHEREHGDL.TST.SLNFMGEISKGVFIIVNQPGR
A0A511Z5K6_9BACL/130-182 .ISEMSITTPHVVEVGDQLQDLGIPLRNGTEV.EPN.ELNFLGRG--DTFMVLVPPGR
M7NBT6_9BACL/137-188 .ISEVGLVTGDVQQAGQTLFDAGLPLR-GTDL.EPD.ELNFIGSG--DAYFVLVPDGR
A0A365KSB3_9BACL/130-182 .ISEVSITTPHVAEVGKQIEDMEIPVRGNKGI.DPG.SLNFLGQG--AAFILLVAPKR
A0A2U3ALH2_9BACL/138-192 .VSEIGLIVTDVEKVGKQLIAEGILRNDEGEI.SMS.NLNFMGLSSVGVYLILSKPGR
A0A1Q2L4G1_9BACL/130-182 .ISEINITTPFMEEVGSLLQASGIQIWGSNGI.DPK.SLNFLGQG--DAFILLLPPKR
A0A5J6PMF7_9BACI/137-192 .ISEIGLTTKNILNSAEQILHLGIPPQDGKIVdEVD.YLNFMGEQEDGAYILLGPVRR
A0A1I6AC97_9BACI/130-182 l-SEVSITTPFVEETGEKLQSIGIPISGHVQI.EPD.ELNFLGKK--DTFILLVPPQR
A0A4Q4IDD2_9BACL/134-186 .ISEINLTVKDVLRAGQLLNKQGYYPLKNEQL.NER.TLNFIGDF--HAYFLLGPTHR
A0A3P5XLC5_9BACL/130-182 .ISEVGITTQYVADVGDQLQDFGIPLRGGTEV.DPD.SLNFLGKG--DTFIVLVPPAR
F2F3L6_SOLSS/1-52 .---MSIVVKDKLKSVSALHAVSIFERDHKEI.AAE.GLTFMGARKDASYLLFVNEGR
A0A0M1NU26_9BACI/135-189 .ISEIGLIVEDTISVSEKLKEIGVYERDNHTI.SKN.FLNFMGERRNGVFIILAQPGR
A0A3D8YVC1_9BACL/135-189 .ISEISLTVPDVIKVGSQLMALGIKERDNDPL.SAT.SLNFMGDPTDEVFVLLVQPGR
A0A859FJC7_9BACI/135-189 .ISEIGVTVHDVARAADELNSIGISKMNNGLI.DRT.SINFMGEKNEGVFIILNQPGR
A0A6B3W4Z8_9BACI/135-189 .VSEIGISANEIKHYADQLIEMGIPQRDNRPL.SNK.NLNFMGEYEDGVFIILGPIGR
A0A4V1W9R6_9BACL/89-141 .ISEINLTVKNVLEEGKKLMKQGFQPIDHKPL.TAH.GLNFIGDF--HSYFLLGPENR
A0A2C0Z9D9_9BACI/135-186 .ISEINLTTHDVFTVGKQLISNGILERNNNEL.-IN.GLNFMGGK--GCFILLGPPNR
A0A5J6PQQ3_9BACI/130-182 .VSEVSITTPFVKEVGEQLQALGISVSGHVSI.EPE.ELNFLGRK--DTFILLVPPKR
A0A2N0Z4B6_9BACI/137-192 .ISEIGLGTDEIKEYADKIQHLGIPIRHQKKLyEEK.YLNFFGEYEEGAFIILSPLGR
A0A0J1IMB8_NIACI/136-190 .ISEIGVTVSDVAAAGKRLMEVGINERDNKPL.DLT.SINFMGDKSKGIFLILNKPGR
V6J0E9_9BACL/134-186 .ISEINLTVNDVLVEGKKLLNQGFKPLDNKPL.NEK.GLNFMGDF--KGYFLLGPVNR
A0A127VXT0_SPOPS/135-189 .ISEIGLIVKDSPRVGEQFKEINIFDSDNDPI.TTS.SLNFMQENKNGVFIILTSIGR
A0A3M8HGG2_9BACI/136-190 .IGEMNLTTDDLMYVGKQLITIGIPVRNNEKL.DET.SLNFMGEADDGVHLLLGPSKR
A0A6G1X549_9BACI/135-187 .IAEVSLVIDDVDGAGERLNKIGLTERNEEPI.DSE.SLNFIGEG--GAYILLTQPGR
C4L1W6_EXISA/136-190 .IGEMSLTVEDPSLVAKALETIGVRRRDANSI.DPR.HLNFMGPPNHDTYMLLVPRGR
A0A0N0S3W5_9BACI/136-190 .ISEMNVTTDDVLHVGETLKQLGIPVRHNEQL.AEN.TLNFIGDHEDGTFILLGPSDR
A0A264W1A9_9BACL/138-192 .VSEMSLVVHDKLAAAEQLETVGVLSRDHQPV.PSE.GLTFMGEREDAAYLLLVPKNR
A0A0Q3RXB5_9BACI/130-182 l-SEVSITTPFVKEVGDQLQNIGIPISGHVDI.EPD.ELNFLGTK--DTFILLVPPNR
A0A0M1NYT6_9BACI/136-190 .ISEINITTDEVRALGNRLISNGVPVRNGEAI.RED.GLNFMGEHEAGSFLLLGPRKR
A0A1H1DZQ3_9BACI/136-190 .ISEIGLTVDDAIDAGERLIDIGIHERDNSPL.TST.TLNFMGDSSKGIFIILTQPER
A0A371S750_9BACI/134-188 .ISEIGLTVDDTVGVGNKLIEIGIHERNNESL.SQT.SLNFMGEKTKGVFIILNQPGR
A0A0J6FY76_9BACI/136-190 .ISEINLTTNEVISVGRKIREFGIPVRNNESL.LED.SLNFLGEKEGGCFILLGPPKR
B1YFD6_EXIS2/136-190 .IGEMNVTTPDVASVGAQFAELGVFHRYHQPI.NVD.FLNFLGASEDGTHLLLGREDR
A0A2V3WC79_9BACI/135-189 .IGEISLTVPDVQYVGQQLIDIGINERNNRPL.STT.SLNFMGDKTTGAFILLVQPGR
A0A1S2QQA5_9BACI/135-189 .ISEIGLVVKYAVSVSEKLNEIGLTERDNDAI.SST.SINFMGERSSGIFIILVQPGR
A0A127VY77_SPOPS/135-189 .ISEISMTVDDAISVGEKLSVIGVTERDNNAI.STN.MLNFLGERKNGVFILLTQPGR
A0A1G8WQF1_9BACI/179-233 .IGEINLTTRKVADAAAKLNQSGILVRDNEPL.EPD.GLNFMGEMTGGSFLLLGPPQR
A0A0A8JMJ5_BACSX/130-182 .VSEIGIVTPFVTDVGEQLMDAGIPLRKGTEV.DPS.GLNFLGQD--DWYVVLVPPGR
A0A1V2S978_9BACI/135-189 .ISEIGLVVQDAPRVGERLKEINIFESDHDPI.TNS.SLSFMQEIENGVFILLTGVGR
A0A2S1H2S8_9BACI/135-189 .ISELSLVVPDTLSAAEQLAQIQIMKREHSVI.SKN.SLNFMSDQKTKVYLLLVGPGR
A0A3M8P667_9BACL/130-182 .ISEVSITTPFVEEVGRQIEDMEIPVRGNKGI.DAK.SLNFLGQG--DAFIILVAPKR
A0A1C0Y6L2_9BACL/134-189 m-SEMSLVVADKVAAAKQLEDVQVVPRNGDRV.DPDgGLYFLTQQNMPIYLLLVSPFR
A0A1G7YX56_9BACL/130-182 .ISEVSITTAHVEEVGRKIEAMEIPVRGNKGI.EPN.ALNFLGQD--DAFILLVAPKR
A0A2S5GE08_9BACL/120-171 .VSEINVTTPDVSKAAEALREEGV-LSEKKMI.HPQ.ELNFVGEG--EAFILLGPPKR
A0A221MCP6_9BACI/135-189 .ISEISLTVDDAINVGEKLNNIGVTERDNNAI.SPK.LLNFMGEKANGIFILLIQPGR
A0A0W7YDT6_9BACI/136-190 .IGEINVTTDDILAAARKLNEYAIKPINDQKI.QPD.ALHFLGNYEDGANILLGPSER
A0A6L6GZT7_9BACL/130-182 .ISEVSITTPFVEEVGRQIEEMDIPVRGNKGI.DPD.SLNFLGGG--DAFIILVAPKR
A0A098EP74_9BACL/138-190 .ISEVSITTPHVKEVGEQLEDLEIPVRGNKGI.DPA.ALNFLGSG--DSFILLVAPKR
I8UKG5_9BACI/135-189 .ISEIGLIVKDAPMVGEKFKEFAIFDSDNDPV.THS.SLNFMQDHNNGVFIILTSVDR
A0A5J6STP3_9BACI/130-182 l-SEVSITTPFVEEVGEQLQNIGIPISGHVDI.EPN.ELNFLGSK--ETFILLVPPKR
A0A1H3ZG03_9BACI/134-188 .ISEMSLTVDDAITAGKELKDIGIKERDDESI.SST.SLNFMGDRASGVFLLLVQPGR
A0A0B4R8I9_9BACL/130-182 .ISEVSITTTYVEEVGELIEDMDIPVRGSKGI.EAK.SLNFLGSG--HAFILLVEPKR
A0A0C2S510_9BACL/133-184 .ISEINLTTDDVLEAAEQLQKEGI-LAENKTI.HPQ.ELNFVGDG--EAFILLGPPER
D5DUW9_PRIM1/135-186 .IGEINLTTPHVHSVGTQLINSGITVRNNRLL.-NE.TFNFLGSG--SAFFLVGTPKR
A0A2D1SSE4_9BACL/135-189 l-SEMSLIVPDKMDVVNYLMNNHIVERSDSEI.TST.SLSFMSDKKTKVYLLLASSNR
A0A0M0GL48_9BACI/135-190 .ISEIGISSEEVYRCSQEVMAKGIPLRNDRPLsNGE.TLNFMGEVGDGAFIIIARAGR
A0A0A3IBU7_9BACI/134-189 .ISEIGVSTNDVKIVVEELMGMGIFPRNNENIyESQ.FLNFMGEAEEGNYIIVGPVGR
A0A345PE69_9BACI/135-189 .ISEIGLTVADAISAGEKLIEVGINERDNDPL.SST.SLNFMGEKSKGIFIILNQPGR
A0A0A3HX98_9BACL/136-190 .IGEINLTTEDLLVVGQKLVSLGIPLQNGAEL.DET.SLNFMGEPNSNAYILLGPAKR
#=GC seq_cons .ISEIulTssDlhplGcpLpphGI..Rsscsl.sss.sLNFhG-tttssFILLssssR
//
