#=GF ID   US2
#=GF AC   PF02476.19
#=GF DE   US2 family
#=GF AU   Mian N;0000-0003-4284-4749
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_2256 (release 5.4)
#=GF GA   25.00 25.00;
#=GF TC   31.10 30.10;
#=GF NC   24.30 22.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8380320
#=GF RT   Analysis of the nucleotide sequence of five genes at the left
#=GF RT   end of the unique short region of the equine herpesvirus 4
#=GF RT   genome. 
#=GF RA   Nagesha HS, Crabb BS, Studdert MJ; 
#=GF RL   Arch Virol 1993;128:143-154.
#=GF DR   INTERPRO; IPR003485;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of unique short (US) region proteins from the 
#=GF CC   herpesvirus strain. The US2 family have no known function. 
#=GF SQ   28
#=GS Q5PP72_9ALPH/135-256      AC Q5PP72.1
#=GS A0A1V0M8M6_9ALPH/120-238  AC A0A1V0M8M6.1
#=GS US02_HHV2H/110-246        AC P13292.3
#=GS Q6R5Q3_9ALPH/120-237      AC Q6R5Q3.1
#=GS US02_EHV1B/111-262        AC P28964.1
#=GS A0A286MM82_9ALPH/107-179  AC A0A286MM82.1
#=GS US02_GAHVM/120-237        AC Q9E6L9.1
#=GS A0A068EPE8_9ALPH/120-238  AC A0A068EPE8.1
#=GS Q782M7_9ALPH/120-237      AC Q782M7.1
#=GS A0A1S6JLR1_HSVA1/108-250  AC A0A1S6JLR1.1
#=GS A0A0Y0DAF2_9ALPH/108-249  AC A0A0Y0DAF2.1
#=GS G9CUK0_9ALPH/120-237      AC G9CUK0.1
#=GS A0A1R3T8S2_9ALPH/119-225  AC A0A1R3T8S2.1
#=GS A0A077B9T6_9ALPH/111-261  AC A0A077B9T6.1
#=GS US02_HHV11/110-247        AC P06485.3
#=GS Q67639_ILTV/100-200       AC Q67639.1
#=GS A0A060Q503_9ALPH/110-251  AC A0A060Q503.1
#=GS E2IUH4_SHV1/110-232       AC E2IUH4.1
#=GS J9R0A8_9ALPH/178-308      AC J9R0A8.1
#=GS A0A089N874_9ALPH/1-103    AC A0A089N874.1
#=GS L0N6M9_HHV1/110-247       AC L0N6M9.1
#=GS Q5EGY0_CHV16/111-255      AC Q5EGY0.1
#=GS Q77L60_MEHV1/120-237      AC Q77L60.1
#=GS O41521_9ALPH/116-254      AC O41521.1
#=GS B1A4T1_9ALPH/119-238      AC B1A4T1.1
#=GS A0A1L5JKK5_9ALPH/110-226  AC A0A1L5JKK5.1
#=GS Q8V727_CHV1/110-256       AC Q8V727.1
#=GS K9MEX8_9ALPH/110-248      AC K9MEX8.1
Q5PP72_9ALPH/135-256                 .......YLNSGARGT.APIHLWILGAADLCDQVLLAAS---...RSTAAGAPGAPT.GARLT---.......RRRPGLTDA........--..................----DALDV..IVAGIPATRAMFARVHNrswrha....gewteaLHAQIVTR.GDVRRRRGGRGNGRE...--RAPRCTI-s...........................................................
A0A1V0M8M6_9ALPH/120-238             .......YLESGIMSG.GPFSLWIIGAADLCKEAIEHIPTPK...RMFALQVKGTWS.GMPWAIPE.......AIPVLLESS........WS..................PQFTHPLDQ..RGFLESGMRGVYKVIGR................-----ASD.PPRNNSEPETRKPRG...RLLKYLCCG-c...........................................................
US02_HHV2H/110-246                   .......LLHQERPGPhRLYHLWVVGAADLCVPFFEYAQKTRlgfRFIATKTNDAWV.GEPWPLPD.......RFLPERTVS........WT..................PFPAAPNHP..LENLLSRYEYQYGVVVPgdrer......sclrwLRSLVAPHnKPRPASSRPHPAT--...HPTQRPCFTC............................................................
Q6R5Q3_9ALPH/120-237                 .......MLESEVSGN.APHSLWIVGAADICRIALECIPLPK...RLLAIKVSGTWS.GMPWAIPD.......NIQTLLTST........WE..................PKFDTPEDR..AHFCDSDMVCVYKILGS................--------.PPNPLKPPEIEPPQMs.sTPGRLFCC--gk..........................................................
US02_EHV1B/111-262                   .......HLNSSLIIN.QPYHLWVLGAADLCKPVFDLIPGPK...RMVYAEIADEF-.HKSW-QPPfvcgklfETIPWTTVE........HNhplklraaggedtvvgecGFSKHSSNS..LVRPPTVKRVIYAVVDP................ARLREIPA.PGRPLPRRR------...----------pseggdarpeaalarsrarsv.......................................
A0A286MM82_9ALPH/107-179             ......q-LHTDDPEG.GPYHLWLFGAADLCAPAFTSIPAAR...RLVYARLNSFVG.GSPWRPPV.......CGQARILVP........WN..................P--------..-----------------................--------.---------------...----------egrgkcm.....................................................
US02_GAHVM/120-237                   .......MLESEVSGN.APHSLWIVGAADICRIALECIPLPK...RLLAIKVSGTWS.GMPWAIPD.......NIQTLLTST........WE..................PKFDTPEDR..AHFCDSDMVCVYKILGS................--------.PPNPLKPPEIEPPQMs.sTPGRLFCC--gk..........................................................
A0A068EPE8_9ALPH/120-238             .......YLESGIMSG.GPFSLWIIGAADLCKEAIEHIPTPK...RMFALQVKGTWS.GMPWAIPE.......AIPVLLESS........WS..................PQFTHPLDQ..RGFLESGMRGVYKVIGR................-----ASD.PPRNNSEPETRKPRG...RLLKYLCCG-c...........................................................
Q782M7_9ALPH/120-237                 .......MLESDVSEN.TSYSLWIVGAADLCRAALEYIPLPK...RLLAVKVAGTWS.GMPWALPD.......TIPTLLTST........WE..................PTFETAEDK..EHFRDNGMTCVYKIIGS................-----PPD.PPKPPRTEPSRASSR...-SDKVFCCW-p...........................................................
A0A1S6JLR1_HSVA1/108-250             ....ral------ADP.RLIHLWVVGAADLCAPLLEGLRSGA...RLVAIQVGGLWGeGRGWQLGA.......HVAPG-TST........WT..................PTPPPTEGP..LAEALRGCAYRYAIIPSaear........aadeR-------.---------------...----------raaaairaagrdgrgplarllaavwprrhqeaaapqtavdeerpaa..............
A0A0Y0DAF2_9ALPH/108-249             .hncdak---------.KLYHMWVIGAADICDPFLSCLQQKAagvRFITIKMDFIWE.GAAWLPPP.......RMCPKKTVP........WV..................PCPISQDPA..LEQLLSNCSYEYGVVGPpprprgc..larvsawF-------.---------------...----------kqsrprrnsamlvpswqmepmeldqpptkdrmkgss........................
G9CUK0_9ALPH/120-237                 .......MLESEVSGN.APHSLWIVGAADICRIALECIPLPK...RLLAIKVSGTWS.GMPWAIPD.......NIQTLLTST........WE..................PKFDTPEDR..AHFCDSDMVCVYKILGS................--------.PPNPLKPPEIEPPQMs.sTPGRLFCC--gk..........................................................
A0A1R3T8S2_9ALPH/119-225             ylnsign------GQT.DRFRLWIIGAADICQQALSSFPKNM..mRRITVKVNGEWP.GNPCFLDT.......NLEPVLISS........WK..................PVSWPE-KE..NNIDTSKLLCRYELLIP................--------.---------------...----------senitadvtrdrkcc.............................................
A0A077B9T6_9ALPH/111-261             .......HLNSSVMGN.RPYHLWVFGAADICRPVFDLLPGPK...RLVYAELSEEWP.GPSW-QPPfg...cgR--RFPAVP........WTav.............gelAPERGTPAD..LEVPPRVARMVYAVVNR................TRPGERNP.PAIPAGSPPS-----...----------ggkswlrsrplrhvpgratpatpsvstpsgrgrcas........................
US02_HHV11/110-247                   ......l-LHRDQPSPpRLYHLWVVGAADLCVPFLEYAQKIRlgvRFIAIKTPDAWV.GEPWAVPT.......RFLPEWTVA........WT..................PFPAAPNHP..LETLLSRYEYQYGVVLPgtngre....rdcmrwLRSLIALH.KPHPATPGPLTTSHP...--VRRPCCAC............................................................
Q67639_ILTV/100-200                  .......HLSSGAYAA.KEFHLWVLGTADICMAALN-LPAPK...TFLITETG----.--------.......---------........--..................---------..-----------------................--------.---------------...----------gknfergveiflvngdkttlslshpsvwttlapsslrtpwpystvkflkvkpnsaaycvs
A0A060Q503_9ALPH/110-251             ......l-LHGPRDRP.RLYHMWVVGAADLCAPFLESLWRMRvgvRLITIKIPDGWV.GASWHLPE.......PFLPATSVA........WT..................PFPAPPNHP..LESLLQNYEYRYGILSPaasqph...rkscgrwLRN-----.---------------...----------lvnkwknmggrptlppatsefhitqnscpacr............................
E2IUH4_SHV1/110-232                  ....ars------SDQ.RLFHVWIVGAADLCEPLLACLSTGA...RCVVIEIGGLWGeGRSWLPPA.......YARSGASTS........WT..................PLPPPTGSA..AESALEGCEYRYAIIPG................--VEARRR.PASRDENDERSG---...----------gegnapgrserswvcq............................................
J9R0A8_9ALPH/178-308                 .desgpg---------.ELFAVWVVGGADICAPAMEAMMALGrpfRVVAIAGAHSLT.GSSWPISA.......RLLPAVWHS........WE..................PYPAAPTNP..LKNTFAACTFVAGTVNA................---ARKPA.PSRLARWLGALTSHT...----------rpqvsaargqpsvtacpect........................................
A0A089N874_9ALPH/1-103               .......---------.----MWVFGAADLYAPIFAHIAATT...RLVYAQLDCTFA.GAAWRLP-.......RRGPAIASP........WP..................PYDTPTLPE..LVAGGVLLRLVYEVVDR................---SAAPR.PAKREPPCPGGLPPR...----APCA--il..........................................................
L0N6M9_HHV1/110-247                  ......l-LHRDQPSPpRLYHLWVVGAADLCVPFLEYAQKIRlgvRFIAIKTPDAWV.GEPWAVPT.......RFLPKWTVA........WT..................PFPAAPNHP..LETLLSRYEYQYGVVLPgtngre....rdcmrwLRSLIALH.KPHPATPGPLTTSHP...--VRRPCCAC............................................................
Q5EGY0_CHV16/111-255                 ......a-LCDPRPRP.RLYHLWVVGAADLCAPFLEHLRDGRvgaRLVAVRVPDAWAeGGSWPLPE.......GLALGETVP........WT..................PFPTAHNHP..LAALFGTYEYRYGVLRPrdatasr..pggcvgwLREAASRL.WAGPPATATEAAQKRtepHPARRPCTAC............................................................
Q77L60_MEHV1/120-237                 .......MLESEASDN.VSYSLWILGAADICRTAIESIPLPK...RLFAIKVPGTWA.GMPWAIPC.......EIQTLLTST........WE..................PKFENIEDK..AYFNDSNMACVYQIIGS................--------.PPDVPQLQGLGIESTc.tPPKRNLCCC-l...........................................................
O41521_9ALPH/116-254                 .......YLNSGIFGN.YPLNLWVFGAADLCEPVISNIPGPK...RLIYAYVSCEWP.EPSW-KPEcleisknNVKHIDDSGsvycpsfiWV..................PVLDTFLSS..FKVPPMLSDIFYGTTFNt..............pFNFESSPR.CPSISSSSSSSSSSS...----SSC---sashys......................................................
B1A4T1_9ALPH/119-238                 .......HLSSGILGN.HTFDMWIIGAADICKPAIEQLPNSK...RFITIKVPGTWS.GLTWEKPD.......GLSPLTVTE........WD..................PCDDETMSKdiIEKKLVGIKCCYDLIGQ................--------.PAAAKHNSELDDSKDv.kCCNGPACCI-a...........................................................
A0A1L5JKK5_9ALPH/110-226             .......LLNSGRAGT.RPFHVWVFGAADLYAPVFAHVAAPT...RLVYAQLDCAFA.GAAWRLP-.......RRGPAIASS........WP..................PYETPTLPE..LLAGGVLLRLVYEVVDR................---GAAPH.PHRRAPRGRDTEPRG...---RAPCAI-l...........................................................
Q8V727_CHV1/110-256                  ......s-LCEPRPRP.RLYHLWVVGAADLCVPFLEHLRRARvgaRLVTIRVTDAWAeGGSWPLPD.......GLAVGETVP........WT..................PFPTAHNHP..LAALFGGYEYRYGVVRPndvvaaaprprgcmgwLRETVPRL.WPGSESAAAEAAKTPtepHPARRPCVAC............................................................
K9MEX8_9ALPH/110-248                 .......LLHREHPGPhRLYHLWVVGAADLCVPFFEYAQKTRlgfRFIAIKTTDAWV.GEPWPLPD.......RFLPERTMS........WT..................PFPAAPNHP..LETLLSRYEYQYGVVVPgpgere....rsclrwLRSLVAPHnKPRPASSRQHPAS--...HPTQRPCFAC............................................................
#=GC seq_cons                        ........Lpsthsss.p.a+LWllGAADLCtPslEplsts+...RhlslclsssWs.GtsWhlPs.......ph.shhoss........Ws..................Ph.sssts...hthh.sshchhYtllss..........................sp..p....t.............Ch..............................................................
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