#=GF ID   VPR
#=GF AC   PF00522.22
#=GF DE   VPR/VPX protein
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_100 (release 1.0)
#=GF GA   25.50 25.50;
#=GF TC   40.90 40.60;
#=GF NC   24.80 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Vpr
#=GF DR   INTERPRO; IPR000012;
#=GF DR   PRINTS; PR00444;
#=GF DR   SCOP; 1dsk; fa;
#=GF DR   HOMSTRAD; VPR;
#=GF DR   TC; 1.A.42;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF SQ   46
#=GS VPR_HV192/1-83         AC O12160.1
#=GS VPR_HV1BR/1-83         AC P05928.1
#=GS VPR_HV1B1/1-76         AC P69725.1
#=GS VPR_SIVEK/1-83         AC Q1A247.1
#=GS VPR_HV1JR/1-83         AC P20883.1
#=GS C7TQA1_9HIV1/1-83      AC C7TQA1.1
#=GS Q5QGH2_SIV/2-84        AC Q5QGH2.1
#=GS VPR_HV1ET/1-83         AC Q75004.1
#=GS VPX_HV2BE/5-99         AC P18099.1
#=GS VPR_HV1YF/1-83         AC O91082.1
#=GS Q77Y31_9PLVG/5-99      AC Q77Y31.1
#=GS A0A7X1LU91_9ACTN/1-83  AC A0A7X1LU91.1
#=GS Q77NU5_9HIV1/1-83      AC Q77NU5.1
#=GS C7TQ89_9HIV1/1-83      AC C7TQ89.1
#=GS C7TQ95_9HIV1/1-83      AC C7TQ95.1
#=GS A0A1B4WRK8_SIV/9-107   AC A0A1B4WRK8.1
#=GS VPX_SIVSP/5-99         AC P19508.1
#=GS VPR_HV2BE/6-87         AC P18100.1
#=GS VPR_HV2RO/6-88         AC P06938.1
#=GS VPR_HV1RH/1-83         AC P05954.1
#=GS B3CKH0_SIV/7-90        AC B3CKH0.1
#=GS C7TQ77_9HIV1/1-83      AC C7TQ77.1
#=GS VPR_HV1MA/1-83         AC P05955.1
#=GS VPR_SIVMB/1-83         AC Q1A265.1
#=GS Q89552_SIV/5-99        AC Q89552.1
#=GS Q87110_SIVSA/23-116    AC Q87110.1
#=GS W8E7N1_9PLVG/1-83      AC W8E7N1.1
#=GS VPX_HV2EH/4-98         AC Q89721.1
#=GS Q74231_HV2EH/31-113    AC Q74231.1
#=GS VPR_HV2EH/6-88         AC P0C1P6.1
#=GS VPR_SIVTN/1-83         AC Q8AIH9.1
#=GS VPR_HV1AN/1-83         AC Q77375.1
#=GS VPR_SIVCZ/1-83         AC P17287.1
#=GS VPR_HV1EL/1-83         AC P05956.1
#=GS VPX_HV2RO/5-99         AC P06939.1
#=GS Q88017_9PLVG/2-84      AC Q88017.1
#=GS VPX_HV2KR/5-99         AC Q74122.1
#=GS B7UES3_SIV/2-94        AC B7UES3.1
#=GS VPR_SIVSP/2-84         AC P19509.1
#=GS VPR_HV2KR/6-88         AC Q74123.1
#=GS Q9WLL8_9HIV1/1-83      AC Q9WLL8.1
#=GS VPR_HV1H2/1-83         AC P69726.2
#=GS VPR_HV1VI/1-83         AC Q9QSR1.1
#=GS VPR_HV1MN/1-83         AC P05950.1
#=GS VPR_HV193/1-83         AC O70888.1
#=GS C7TQ83_9HIV1/1-83      AC C7TQ83.1
VPR_HV192/1-83                    .................MEQAPED...QGPQREPYNEWTLELLEELKREAVRHFPRPWLHGLGQHIYETY.G.DTWTG.....VEAIIRILQRLLFVHFRIGCQ.........HSRIG-i..........
VPR_HV1BR/1-83                    .................MEQAPED...QGPQREPHNEWTLELLEELKNEAVRHFPRIWLHGLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-v..........
VPR_HV1B1/1-76                    .................MEQAPED...QGPQREPHNEWTLELLEELKNEAVRHFPRIWLHGLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFIHFQ----.........------nwv........
VPR_SIVEK/1-83                    .................MEQAPED...QGPQREPYNEWALELLEDLKNEALRHFPRPWLHGLGQYFYNTY.G.DTWEG.....VEAIIRTLQQLLFIHYRIGCQ.........HSRIG-i..........
VPR_HV1JR/1-83                    .................MEQAPED...QGPQREPYNEWTLELLEELKNEAVRHFPRIWLHSLGQYIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-i..........
C7TQA1_9HIV1/1-83                 .................MEQAPED...QGPQREPYNEWMLELLEELKHEAVRHFPRPWLHGLGQHIYETY.G.DTWEG.....VEAIIRILQQLLFIHFRIGCQ.........HSRIG-i..........
Q5QGH2_SIV/2-84                   .................EERPPEN...EGPQREPWDEWVVEVLEELKEEALKHFDPRLLTALGNHIYNRH.G.DTLEG.....AGELIRILQRALFMHFRGGCI.........HSRIGQ...........
VPR_HV1ET/1-83                    .................MEQAPED...QGPQREPYNEWALELLEELKQEAVRHFPRPWLHNLGQYIYETY.G.DTWSG.....VEALIRTLQQLMFIHFRIGCQ.........HSRIG-i..........
VPX_HV2BE/5-99                    .................RERVPPGnsgEETIGEAF-EWLERTIEALNREAVNHLPRELIFQVWQRSWRYW.H.DEQGMsasytKYRYLCLMQKAIFTHFKRGCTcw....gedMGREG-l..........
VPR_HV1YF/1-83                    .................MERAPED...AGPQREPYNEWALELLEELKNEAVRHFPRIWLHGLGQHIYNTY.G.DTWEG.....VEAIIRILQQLLFIHYRIGCQ.........HSRIG-i..........
Q77Y31_9PLVG/5-99                 .................RERIPPGnsgEETIGEAF-EWLNRTVEEINREAVNHLPRELIFQVWQRSWEYW.H.DEQGMspsyvKYRYLCLIQKALFMHCKKGCRcl....gegHGAGG-w..........
A0A7X1LU91_9ACTN/1-83             .................MEQAPED...QGPQREPYNEWTLELLEELKSEAVRHFPRIWLHNLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-v..........
Q77NU5_9HIV1/1-83                 .................MEQAPED...QGPQREPYNEWTLELLEELKSEAVRHFPRVWLHSLGQYIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCQ.........HSRIG-i..........
C7TQ89_9HIV1/1-83                 .................MEQAPED...QGPQREPFNEWMLELLEELKHEAVRHFPRLWLQGLGQHIYGTY.G.DTWVG.....VEAIVRILQQLLFVHFRIGCN.........HSRIG-i..........
C7TQ95_9HIV1/1-83                 .................MEQAPED...QGPQREPYNEWTLELLEELKQEAVRHFPRPWLHGLGQHIYETY.G.DTWGG.....VEAIIRILQQLLFVHFRIGCS.........HSRIG-i..........
A0A1B4WRK8_SIV/9-107              .................RERRPGWleiWDLSREPWDEWLRDMLTDLNQEARRHFGRELLFQVWNYCQEEG.-.ERNEVpmserAYRYYRIVQKALFVHFRCGCRrrtpfepyeERRN--ge.........
VPX_SIVSP/5-99                    .................RERIPPGnsgEETIGEAF-DWLDRTVEEINRAAVNHLPRELIFQVWRRSWEYW.H.DEMGMsvsytKYRYLCLIQKAMFMHCKKGCRcl....ggeHGAGG-w..........
VPR_HV2BE/6-87                    .................TEFPPED...GTPRRDLGSDWVIETLREIKEEALRHFDPRLLIALGYYIHNRH.G.DTLEG.....ARELIKTLQRALFVHFRAGCN.........RSRIG-...........
VPR_HV2RO/6-88                    ................t-ELPPVD...GTPLREPGDEWIIEILREIKEEALKHFDPRLLIALGKYIYTRH.G.DTLEG.....ARELIKVLQRALFTHFRAGCG.........HSRIGQ...........
VPR_HV1RH/1-83                    .................MEQAPED...QGPQREPYNEWTLELLEELKSEAVRHFPRLWLHSLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCQ.........HSRIG-i..........
B3CKH0_SIV/7-90                   erpptggpqaipedllg-------...---------------MQELFAMAKRHFPREVLVRVFLYCSQQR.NyEEQAT.....MHYFHRVLQRGLYLHLIQGCP.........KE----kenrerdfq..
C7TQ77_9HIV1/1-83                 .................MERAPED...QGPQREPFNEWTLELLEELKHEAVRHFPRPWLHGLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFVHFRIGCN.........HSRIG-i..........
VPR_HV1MA/1-83                    .................MEQAPAD...QGPQREPHNEWTLELLEELKQEAVRHFPRIWLHSLGQHIYETY.G.DTWEG.....VEAIIRSLQQLLFIHFRIGCQ.........HSRIG-i..........
VPR_SIVMB/1-83                    .................MEQLPED...QGPQREPYNEWTLEILEELKREAVRHFPRDWLHQLGQHIYTTY.G.DTWAG.....VEAIIRILQQLLFIHYRIGCH.........HSRIG-i..........
Q89552_SIV/5-99                   .................RERIPPGnsgEETIGEAF-EWLNRTVEEINREAVNHLPRELIFQVWQRSWEYW.H.DEQGMspsyvKYRYLCLIQKALFMHCKKGCRcl....gegHGAGG-w..........
Q87110_SIVSA/23-116               .................REEIPGWletWDLPREPFDEWLRDMLQDLNSEAQCHFPRNLLFRLWWNIVEEP.A.IDHGQtrlegWYKYCRILQKALFVHMKGRCC.........------kpkthpayg..
W8E7N1_9PLVG/1-83                 .................MEQAPED...QRPQRGLHNEWTLALLEELKNEAVRHFPRPWLHGLGQYIYETY.G.DTREG.....VEAIIRILQQLLFIHFRIGCQ.........HSRIG-i..........
VPX_HV2EH/4-98                    .................RERVPPGnsgEETVGEAF-EWLETTLEHLNRVAVNHLPRELIFQVWQKSWAYW.R.EEQGMsisytKYRYLCLMQKAMFIHFAKGCG.........CLREG-hgpggw.....
Q74231_HV2EH/31-113               ................p-EIPPED...KNPQREPWEQWVVDVLEEIKQEALKHFDPRLLTALGNFIYNRH.G.NTLEG.....AGELIKLLQRALFLHFRGGCQ.........HSRIGQ...........
VPR_HV2EH/6-88                    ................p-EIPPED...KNPQREPWEQWVVDVLEEIKQEALKHFDPRLLTALGNFIYNRH.G.NTLEG.....AGELIKLLQRALFLHFRGGCQ.........HSRIGQ...........
VPR_SIVTN/1-83                    .................MEQAPND...NGPQREPYTEWLLDILEEIKQEAVKHFPRPILQGVGNWVFTIY.G.DSWEG.....VQELIKILQRALFTHYRHGCI.........HSRIG-s..........
VPR_HV1AN/1-83                    .................MEQAPEN...QGPAKEPFNEWALELLEELKAEAVRHFPRPWLHALGQYIYETY.G.DTWVG.....VMAIIRILQQLLFTHYRIGCQ.........HSRIG-i..........
VPR_SIVCZ/1-83                    .................MEQAPED...QGPPREPYQEWALETLEELKNEAVRHFPRPWLHQLGQFIYDTY.G.DTWVG.....VEAIIRILQHLLFIHFRLGCQ.........HSRIG-i..........
VPR_HV1EL/1-83                    .................MEQAPAD...QGPQREPYNEWALELLEELKSEAVRHFPRIWLHSLGQHIYETY.G.DTWVG.....VEAIIRILQQLLFIHFRIGCQ.........HSRIG-i..........
VPX_HV2RO/5-99                    .................RETVPPGnsgEETIGEAF-AWLNRTVEAINREAVNHLPRELIFQVWQRSWRYW.H.DEQGMsesytKYRYLCIIQKAVYMHVRKGCTcl....grgHGPGG-w..........
Q88017_9PLVG/2-84                 .................EERPPEN...EGPQREPWDEWVVEVLEELKEEALKHFDPRLLTALGNHIYNRH.G.DTLEG.....AGELIRILQRALFMHFRGGCI.........HSRIGQ...........
VPX_HV2KR/5-99                    ..............rkt---VPPGnggEVTIGEAF-AWLERMVEAINREAVNHLPRELIFQVWQRSWRYW.H.DDLGMsqsytKYRYLRLMQYAMFIHVKKGCTcl....gggHGPGG-w..........
B7UES3_SIV/2-94                   ................a-ERVPED...QGPPREPLEDWVRDTMEEIIVEAKRHFPRELLVRVFLFCAQRHiN.DEMST.....SLLFIRLLQRALFQHYRNGCPg......veL-----rrnphrrsegm
VPR_SIVSP/2-84                    .................TERPPED...EAPQREPWDEWVVEVLEEIKEEALNHFDPRLLTALGNYIYDRH.G.DTLEG.....AGELIRILQRALFIHFRGGCR.........HSRIGQ...........
VPR_HV2KR/6-88                    ................a-EFPPED...ETPPRGPGDEWVIGILRELREEALKHFDPRLLTTLGNYICARH.G.DTLES.....ARELINVLQRALFVHFRAGCK.........ISRIGQ...........
Q9WLL8_9HIV1/1-83                 .................MEQAPED...QGPQREPNNEWTLELLEELKNEAVRHFPRPWLHGLGQHIYNTY.G.DTWEG.....VEAIIRILQQLLFIHFRIGCQ.........HSRIG-i..........
VPR_HV1H2/1-83                    .................MEQAPED...QGPQREPHNEWTLELLEELKNEAVRHFPRIWLHGLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-v..........
VPR_HV1VI/1-83                    .................MEQAPGD...QGPQREPYNEWALEILEELKNEAVRHFPRPWLHGLGQHIYNTY.G.DTWEG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-i..........
VPR_HV1MN/1-83                    .................MEQAPED...QGPQREPYNQWALELLEELKNEAVRHFPRIWLHGLGQHIYETY.G.DTWAG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-i..........
VPR_HV193/1-83                    .................MEQAPED...QGPQREPYNEWTLDLLEELKNEAVRHFPRPWLHSLGQHIYNTY.G.DTWEG.....VEAIIRILQQLLFIHFRIGCR.........HSRIG-i..........
C7TQ83_9HIV1/1-83                 .................MEQAPED...QGPQREPYNEWMLELLDELKHEAVRHFPRPWLHGLGQYIYETY.G.DTWAG.....VEAIIRILQHLLFVHFRIGCN.........HSRIG-i..........
#=GC seq_cons                     .................hEpsPED...pGPQREPasEWslElLEELKpEAVRHFPR.hLauLGQaIYcpa.G.DThsG.....sctlIRILQphLFlHFRhGCp.........HSRIG.h..........
//