#=GF ID   VacA2
#=GF AC   PF03077.18
#=GF DE   Putative vacuolating cytotoxin
#=GF PI   VACA; 
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE   Pfam-B_2866 (release 6.4)
#=GF GA   27.00 27.00;
#=GF TC   34.00 34.00;
#=GF NC   26.90 18.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR004311;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family contains a number of Helicobacter outer membrane
#=GF CC   proteins with multiple copies of this small conserved region.
#=GF SQ   27
#=GS D3UHF9_HELM1/101-160      AC D3UHF9.1
#=GS O25063_HELPY/1163-1222    AC O25063.1
#=GS H5V9B0_HELBI/935-990      AC H5V9B0.1
#=GS E7G467_9HELI/240-299      AC E7G467.1
#=GS O25063_HELPY/700-759      AC O25063.1
#=GS V8CK08_9HELI/98-154       AC V8CK08.1
#=GS O25579_HELPY/1479-1538    AC O25579.1
#=GS O25330_HELPY/974-1033     AC O25330.1
#=GS A0A4U8U765_9HELI/88-147   AC A0A4U8U765.1
#=GS V8CCL5_9HELI/103-162      AC V8CCL5.1
#=GS A0A099TXV3_9HELI/146-205  AC A0A099TXV3.1
#=GS H5V9B0_HELBI/1645-1704    AC H5V9B0.1
#=GS F8KTK3_HELBC/475-530      AC F8KTK3.1
#=GS T1CN16_9HELI/108-168      AC T1CN16.1
#=GS O25330_HELPY/138-197      AC O25330.1
#=GS O25063_HELPY/1799-1858    AC O25063.1
#=GS O25331_HELPY/821-880      AC O25331.1
#=GS D3UHF4_HELM1/168-227      AC D3UHF4.1
#=GS A0A4U8T3P5_9HELI/269-339  AC A0A4U8T3P5.1
#=GS O25579_HELPY/812-873      AC O25579.1
#=GS F8KTK3_HELBC/20-79        AC F8KTK3.1
#=GS O25331_HELPY/117-173      AC O25331.1
#=GS O25579_HELPY/160-220      AC O25579.1
#=GS H5V9B0_HELBI/480-539      AC H5V9B0.1
#=GS O25330_HELPY/555-614      AC O25330.1
#=GS F8KTK3_HELBC/1185-1244    AC F8KTK3.1
#=GS A0A1B8J8V9_9HELI/142-198  AC A0A1B8J8V9.1
D3UHF9_HELM1/101-160                 ...GDVGYITASFNAKNI.YLTSTLGAGNSWRT..GGGASLNFSATQKANLQSLTLEFYKAGTQNS.............................
O25063_HELPY/1163-1222               ...QCIGFITGHYEAQKI.YITGSIESGNRISS..GGGASLNFNGLQGILLTNATLYNRAAGTQSS.............................
H5V9B0_HELBI/935-990                 .np--MGYITGTFNAPNI.YLTNTFKTGN-FAY..GQGAKITFSATDNLTADGFTYSNVAT-----vf...........................
E7G467_9HELI/240-299                 ..a-ALGYIEANFKAKDI.YITGTVGSGNAWGI..GGSADVTFNSATNLTLNQATIDAEGTDQI--fn...........................
O25063_HELPY/700-759                 ...QCTGTTNGTYSAYHV.YITANLRSGNRIGT..GGAANLIFNGVDSINIANATITQHNAGIYSS.............................
V8CK08_9HELI/98-154                  ..g-KSGYISGTWNAKEV.YLTAYLGAGNAEKT..AG-ADLTFNATGDIKAEGLIV----------dmwsntqs.....................
O25579_HELPY/1479-1538               ..p-YLGYINADFKAKSI.YITGTIGSGNAFES..GGSADVTFQSANNLVLNKANIEAQATDNI--fn...........................
O25330_HELPY/974-1033                ...GLVGYIQGVFKANQI.DITGTIRSGNGAKT..GGGATLVFNAQKRLNIANAHLNNDKAGLQNS.............................
A0A4U8U765_9HELI/88-147              ...GRLGFINATFNAKEV.FLTGKIGTGNGWRT..GGGANLTFNANNNLTLDRANISVNRAGTQNS.............................
V8CCL5_9HELI/103-162                 ...GLVGYIKTKFEAKDI.YLTGTIGAGNAWAT..GGGAELNFNASNSFKAESLDLKFNHAGLQYS.............................
A0A099TXV3_9HELI/146-205             ...GILGFITASFSAKEV.YLTGNINTGNSFRT..GGGTNLSFRATGDLNVNQAAITVRRAGLQN-h............................
H5V9B0_HELBI/1645-1704               ...GALGYIDANFNAKDI.YITGTLGSGNATQT..GGSASVSFNSSTNLVLNQANVTAEQTDQ---vfn..........................
F8KTK3_HELBC/475-530                 .np--MGYITGTFNAPNI.YLTNTFKTGN-FAY..GQGAKITFSATDNLTADGFTYSNVAT-----vf...........................
T1CN16_9HELI/108-168                 ...GYVGYMSGTFNVKEA.YLTGTIKGGNNTKV..GAGLTLNINATSDINTDGLNVS---------mwsntqgdqf...................
O25330_HELPY/138-197                 ...GYVGFITGVFKAKDI.FITGAVGSGNEWKT..GGGAILVFESSNELSANGAYFQNNRAGTQTS.............................
O25063_HELPY/1799-1858               ..a-DLGYIDTTFNAKEI.YLTGTLGSGNAWGT..GGSASVTFNSQTSLILNQANIVSSQTDGIFS.............................
O25331_HELPY/821-880                 ..p-YLGYINANFRAKNI.YITGTIGSGNAWGS..GGSANVSFESGTNLVLNQAKIDAQGTDKIFS.............................
D3UHF4_HELM1/168-227                 ...GDVGYITASFNAKNI.YLTSTLGAGNSWRT..GGGASLNFSATQKANLQSLTLEFYKAGTQNS.............................
A0A4U8T3P5_9HELI/269-339             ..g-FLGFTQAEFYAKDI.YLTGNMISGNGIAT..GGGATININGTSQ------------------pvtggalrngnitaeslnifvkragtqgs
O25579_HELPY/812-873                 ..g-GFGYITGTFSAANI.YLTNNFKTGEGVSNsdGGGANITFKASDNITMDGLNYNDAETVTKM-i............................
F8KTK3_HELBC/20-79                   ...GLTGYITGNFKAQNI.YLTSHIQSGNAWGT..GGGTSITYTATDKITMDGLSYQNFKAGTQN-t............................
O25331_HELPY/117-173                 nll----YLHGNFNATNI.FLTNNFNVGNP-NA..GGGATINFNADETLNADGLNYTNFQTV----alg..........................
O25579_HELPY/160-220                 ...GDVGYITGTYDAQTInFNSSHLTTGNSYAD..GGGATLNFNAANNITINQASFDNSHAGTQKS.............................
H5V9B0_HELBI/480-539                 ..g-LAGYITGNFKAQNI.YLTSHIQSGNAWGT..GGGTSITYTATDKITMDGLSYQNFKAGTQN-t............................
O25330_HELPY/555-614                 ...GKTGYITGTFTADRV.YITGNMMTGNGAQT..GGGATLNFVGATEINIAGATFKNLKTTSQNS.............................
F8KTK3_HELBC/1185-1244               ...GALGYIDANFNAKDI.YITGTLGSGNATQT..GGSASVSFNSATNLVLNQANVTAQQTDQV--fn...........................
A0A1B8J8V9_9HELI/142-198             ..g-HTAYLNGTFNVKEA.YFTGTLTTGNNTGA..GAGASLTFNANENITTQGFNAN---------fwsntq.......................
#=GC seq_cons                        ....hlGYIsusFsAcsI.YlTusltoGNuhto..GGGAslsFsussslshsshshps.pss.................................
//