#=GF ID   VipE
#=GF AC   PF20876.1
#=GF DE   Effector protein VipE
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   ECOD:3897.1.1
#=GF GA   27.00 27.00;
#=GF TC   32.60 41.10;
#=GF NC   26.70 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Legionella pneumophila use the Icm/Dot type IVB secretion system
#=GF CC   to deliver into the host cell effectors that inhibit phagosome
#=GF CC   maturation and modulate host vesicle trafficking pathways. VipE
#=GF CC   is one of those effectors. This protein shows an
#=GF CC   all-alpha-helical fold.
#=GF SQ   7
#=GS A0A0W0YRK4_9GAMM/1-125   AC A0A0W0YRK4.1
#=GS A0A0W0Y088_9GAMM/21-163  AC A0A0W0Y088.1
#=GS G9EMR5_9GAMM/1-125       AC G9EMR5.1
#=GS Q5ZRR7_LEGPH/1-125       AC Q5ZRR7.1
#=GS A0A0W0Z6Y1_LEGSP/18-159  AC A0A0W0Z6Y1.1
#=GS A0A0K2E032_PISSA/37-139  AC A0A0K2E032.1
#=GS G9EP01_9GAMM/1-125       AC G9EP01.1
A0A0W0YRK4_9GAMM/1-125              .....................MPLSQTKILVNTYGRKLQDGSISDAEIDYL....LQNDTFKKSEGYVDTSKPLSDSNFSKMDSIKDFVLTIAPTIPQDKLHDLTARLIARSPE.....G.DKNTFMRGSSLEKAFLAYE...LLHYPATAEA...........HFDSER..........................
A0A0W0Y088_9GAMM/21-163             ....................e-PMQHTRSIVQRWHKQLLSADFSIEDIKRLeneiLQDSRFHPIDLSSNEKITYSDSAYTQKEAMIDFVLAVCPYLSLHGLHQLTSLALTKEIN.....T.IDNTFLRNNELARYLLVYEagiYASKPSELEAmllsqfkeiagYFSE--eg........................
G9EMR5_9GAMM/1-125                  .....................MLLKQTNTLMKRYGEKLINGTISDRELKTL....MDLKSFPKSKGFVDINQPITDKNHRKSDAINDFVLAIAPRLTLATLHQLTARMINLAPD.....A.GRNTFMRNEGLEKAFLAYE...LAQFPQSAAI...........FFLKP-e.........................
Q5ZRR7_LEGPH/1-125                  .....................MPLTQTQRLINTYGASLKNGTISNEELIIL....LDPNTFTKSEGYVDPNAPVSDSNHSKMDAIKDFVLTIGPTLDSEILHQLTSRMIELSPP.....G.DRNTFMRGSSLEKAFLAFE...MAHYPTKAEE...........HFNST-r.........................
A0A0W0Z6Y1_LEGSP/18-159             ....................t-PMKHTRQVLSAWRDKILHGDLTITDIEKLekdiVSGGGYHPLTIDSQNKLTYDDQGYTQQEAVIDFVLAVCPYLSAARLYRLTEMALAKEIS.....GaVDNTFLRNNELARYLLVYE...TG--------...........------ihtkteeipdvlkahlepltrqfsee
A0A0K2E032_PISSA/37-139             faqlerllgrnctgrsrkygk------------------------------....------------------INYDSHTQLQAICEYVLCLSVGLNDDELHQITKAALENYNSgcaagA.DGTCYMRNNSFAKFVLAQE...LRRNPASAEQ...........HFSD--gs........................
G9EP01_9GAMM/1-125                  .....................MPLKQTKKLITAYEKKLINGTITDHELTIL....MDKSSFPKSEGYVHPNKPMTEKNHSQMDAIIDFILLVAPKLTREVLHQLTARMISLTPD.....Q.GANAFMRNTTLEKYFLAYE...LFQFPKSAQL...........FFEAN-a.........................
#=GC seq_cons                       ......................PhppTppllptatcpLhsGslo.p-lphL....hp.ssF...ch.sp.phshoDpsaoph-AIhDFVLsluPtLstctLHQLTuthlshpss.....u.scNTFMRNssLtKhhLAYE...htphPtpAp............aFpp..t.........................
//