#=GF ID   WTF
#=GF AC   PF03303.17
#=GF DE   WTF protein
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_4183 (release 6.5)
#=GF GA   25.00 25.00;
#=GF TC   25.00 25.00;
#=GF NC   24.60 24.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR004982;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of hypothetical Schizosaccharomyces pombe
#=GF CC   proteins. Their function is unknown.
#=GF SQ   22
#=GS WTF18_SCHPO/166-246  AC O74495.3
#=GS WTF23_SCHPO/1-180    AC O94409.1
#=GS WTF7_SCHPO/1-207     AC Q7Z9I5.4
#=GS WTF18_SCHPO/1-177    AC O74495.3
#=GS G3B662_CANTC/40-170  AC G3B662.1
#=GS WTF19_SCHPO/1-183    AC O74486.1
#=GS WTF9_SCHPO/1-222     AC O74564.1
#=GS WTF13_SCHPO/1-180    AC O74420.3
#=GS WTF21_SCHPO/1-211    AC O74474.1
#=GS WTF5_SCHPO/149-223   AC Q8TF80.1
#=GS WTF20_SCHPO/1-208    AC O74487.1
#=GS WTF16_SCHPO/1-200    AC Q9Y7N5.2
#=GS WTF4_SCHPO/1-234     AC Q9P3V0.2
#=GS WTF23_SCHPO/176-249  AC O94409.1
#=GS WTF10_SCHPO/1-212    AC O74838.1
#=GS WTF25_SCHPO/1-199    AC U3H0P2.1
#=GS WTF11_SCHPO/1-229    AC Q96WS1.2
#=GS WTF12_SCHPO/1-139    AC Q8NIP8.1
#=GS WTF5_SCHPO/1-154     AC Q8TF80.1
#=GS WTF15_SCHPO/1-204    AC G2TRU7.1
#=GS WTF13_SCHPO/177-256  AC O74420.3
#=GS WTF19_SCHPO/203-282  AC O74486.1
WTF18_SCHPO/166-246             .......................................vifl-----------------.---......----------------------------------......---...............................------------------------------..-----------------.------------------------...........-------------------AQC...............VKVTAV...........FLAKCVKVIAVGLYNSKKDL..VVTIWLAWVVICFILFGCVKDGRLNLNKALICSTCSISAALFFILLLV............................
WTF23_SCHPO/1-180               ...........................................MKNKYYPLRSSMDELSA.-KN......DNEIDLEKGPLPEYNSEDGSTLPPYSENINLKDPkqmganNPNlfnt......................desttPPDYGEDSLSITHRENHSSGTADNSSTSPL..KKAFLSFISIFVLNVPA.VCYLTYKDALFKDYGKDEWVYFGV...........WCAICLMIFISLWYFYETWIKA...............VKVTVI...........FLAQCIKVT-----------..------------------------------------------------v...........................
WTF7_SCHPO/1-207                ...........................................MSGSYAPIEDSADELSVhSGN......DNEIDLEKGLLPKCNTGNGGTTPCSEPPHYDSDA......VVEmdmyenniymrtfklrpfaksgvtnssnvvfQMKTYENNRHMQTFRLRPFAKNGVTNG---..VKLAQSLFLLLPFNFIF.FACLFFRKASFTDFSLMGWILFGI...........WCLTCFLSSFILYAYHESWTKF...............------...........--------------------..------------------------------------------------arersqefslilfgllfpgivtmvvfya
WTF18_SCHPO/1-177               ...........................................MKNNYTSLKSPLDEEDE.LKT......DHEIDLEKGLLPEYNSEEEGTLPLYSDISKLANP......VPE...............................DSSTGPTEIANPNVERRQEFKDSHPNIYFL..LRLLISVLAVSVVFFTAwVCVNPLEKSIF---GKVAFSVT--...........IGITCPILFIATFCFFETWTQAva...........qcIKVTVI...........FLAQCVKVTVIFLAQC----..------------------------------------------------vkvta.......................
G3B662_CANTC/40-170             lirrldsldetqisrlseavgarlhnpqippqtplqkrgdksa-----------------.---......--------------KSEDSKTTTSSSKASKTTSS......---...............................KASKTSDSNASSSSSDSKSKSKSNSSPLNMtgIRVAIAFVAIILINMVA.ICIHH-------------------...........----------------------...............------...........--------------------..------------------------------------------------vymklsssersyrt..............
WTF19_SCHPO/1-183               ...........................................MKNKYYPLRSSMDELSA.-KN......DNEIDLEKGPLPEYNSEDGSTLPPYSENINLKDPkqmganNPNlfnt......................desttPPDYGEDSLSITHRENHSSGTADNSSTSPL..KKAFLSFISIFVLNVPA.VCYLTYKDALFKDYGKDEWVYFAV...........WCASCLMIFISLWYFYETWIKA...............VKVTVI...........FLAQCIKVTV----------..------------------------------------------------vfl.........................
WTF9_SCHPO/1-222                ...........................................MKNNYTSLKSPLDEEDE.LKT......DHEIDLEKGPLPEYDSEEEGALPPYSDHALVNNP......-PN...............................-----------THRENHSSGTTDNSSPL-L..IKLLISFTSIILFNAPA.VCYLKYKDAFFKNYGAVEWTLFGF...........WCFVCTLALIFLTYFYETWTKA...............VKVTVIslaqcvkvtavFLAKCVKVTAVGLYNSREKW..VVIIWLLWVVICYTLFLRAKFGNLNLDKALICSTCSISAALLLFLLYV............................
WTF13_SCHPO/1-180               ...........................................MKNKDYPLRSSMDELST.-KN......DNEIDLEKGPLPEYNSEDGSTLPPYSEIWKYIKT......VSE...............................DSSTGPTEIANPNVERRQEFKDSHPNIYSL..LRLLISVLAVIVVFFTAwVCVNPLEKSIF---GKVAFSVT--...........IGITCPIVFIAIFCFFETWTQAva...........qcIKVTVI...........FLAQCVKVTAISLAQCVKVT..------------------------------------------------avfla.......................
WTF21_SCHPO/1-211               ...........................................MKNNYTSLKSPLDEEDE.LKT......DHEIDLEKGPLPEYDSEEEGALPPYSDHALVNNP......-PN...............................-----------THRENNPSRSTDNSSPF-L..IKLLISFTPIYVLNVLA.ICYLTYKDAFFKDYGAAEWTLFGF...........WCLVCTLALIFLTYFYETWVKA...............VKVTVI...........SLAKCVKVISIGLFNIRREM..MIIIWILWLIICCILFVYIKSGDLILNKALICSTCTISAVLLLIVSSV............................
WTF5_SCHPO/149-223              ...........................................-----------------.---......----------------------------------......---...............................------------------------------..-----------------.------------------------...........----------------------...............VKVTAI...........FLAQCVKACGKGIKHFLKKWenMPMAFSEVFLFN-ILVGSPRMNLRYIFGDRWGLKCSLADHIIFVVLSI............................
WTF20_SCHPO/1-208               ...........................................MKNNYTSLKSPLDEEDE.LKT......DHEIDLEKGLLPEYNSEEEGALPPYSDISKLANP......VPE...............................DSSTGPTEIANPNVERRQEFKDSHPNIYFL..LRLLISVLAVSVVFFTAwVCVNPLEKSIF---GKVAFSVT--...........IGITCPILFIAIFYFYETWTKA...............------...........--------CGKGIKHFLKKWrnMFFTFCKSPIFCLVLLKAENKLSSHLGDQQWGWKCSASAFTFMAVSSI............................
WTF16_SCHPO/1-200               ...........................................MKNNYTSLKSPIDEGDE.SKT......GHEIDLEKGLLPEYDSEEEGALPPYSDHARVSNS......-PN...............................-----------THRENNPSRSTDNSSPF-L..IKLLISFTPIYVLNVLA.ICYLKYKDAFFKNYGAAEWTLFGF...........WCLVCTLALIFLTYFYETWTKA...............------...........-----VKVTAVGLYNSRKKW..VVIIWLLWVVICFVLFGCIKFGNLNLDKALICSTCSISAALLLFLLYV............................
WTF4_SCHPO/1-234                ...........................................MKNKDYPLRSSMDELST.-KN......DNEIDLEKGPLPEYNSEDGSTLPPYSEIWKYIKT......VSE...............................DSSTGPTEIANPNVERRQEFKDSHPNIYSL..LRLLISVLAVIVVFFTAwVCVNPLEKSIF---GKVAFSVT--...........IGITCPIVFIVIFCFFETWTQAvaqcikvtviflaqcVKVTAV...........FLAKCVKVIAVGLYNSKKDL..VVTIWLAWVVICFILFGCVKDGRLNLNKALICSTCSISAALFFILLLV............................
WTF23_SCHPO/176-249             ...........................................-----------------.---......----------------------------------......---...............................------------------------------..-----------------.------------------------...........----------------------...............IKVTVV...........FLAQCVKVISIGLFNIRREM..MIIIWLLWLIICCILFGCVKSGDLNLNKALIYSTCTISAVLLLIVSSV............................
WTF10_SCHPO/1-212               ...........................................MKNNCTSLKSSIDEEDE.LKT......DHEIDLEKGLLPEYDSKEEGALPLYSDHARLSNS......-PN...............................-----------THRENNPSRSTDNSSPL-L..IKLLISFTSIILFNAPA.VCYLKYKDAFFKNYGAAEWTLFGF...........WCLVCTLALIFLTYFYETWTKA...............VKVTVI...........FLAQCVKACGKGIKHFLKKWenMPMAFSEVFLFN-IFGGALRIISRHFFGKRWGLKCSLADHIIFAILSI............................
WTF25_SCHPO/1-199               ...........................................MKNNYTSLKSPLDEEDE.LKT......DHEIDLEKGPLPEYDSEEEGALPPYSDHALVNNP......---...............................---------LNTHRENHSYGTTDNSSPL-L..IILLISFTSIILFNAPA.FCYLKYKDAFFKNYGAAEWTLFGF...........WCLVCTLALIFLTYFYETWSKA...............------...........--------CGKGIKHFLKNWrnMIFAFCKSSLFCLVLLKAENKLSSHLGDQRWGWKCSASAFTFMAVSSI............................
WTF11_SCHPO/1-229               ...........................................MNSNYVPLTSSVDVEEK.MESengvdlGNDIDLEKGLPLKYNSENESGLPSNSASSYLINP......DPTmdl........................eaqtFNHNESTTSVGHDNSNSPPKCRKTCSSNKV..YSNEVPLLFVFVISISI.VCIFDL--VIF---GCLQYNMVSMddlhvmqrlswFCASLALLFILMRY-YDFWTKA...............------...........--------CKDGIKHIFKKWknTPLAFLQVLIFNIIGF-FVRKGLKDSFGEQWGLKTSLFAHVSFATMSI............................
WTF12_SCHPO/1-139               ...........................................MKNNYTSLKSSVDEEDE.LKT......GHEIDLEKGPLPEHNSEGESTLPPYSDISKLANL......VPE...............................DSSTGPTETANPNVERRQEFKDLHPNIYSL..LRLLIAVLAVSVVFFTAwGCVNPLEKSTF---GKIAFFVL--...........IGLTCLILLITMI---------...............------...........--------------------..------------------------------------------------le..........................
WTF5_SCHPO/1-154                ...........................................MKNNYTSLKSPLDEEDE.LKT......DHEIDLEKGPLPEYDSEEESTLPPYSDHALVNNP......-PN...............................-----------THRENHSYGTTDNSSPL-L..IILLISFTSIILFNAPE.VCYLKYKDAFFKNYGAAEWTLFGF...........WCLVCTLALIFLTYFYETWTKA...............VKVTVI...........SLAKCVKVTA----------..------------------------------------------------i...........................
WTF15_SCHPO/1-204               ...........................................MSNNYTSLSSSLDEEMG.LKA......GHEIDLEGSPPSEHNSEEKSTLPSNSDILTSANP......VSQ...............................ASE-----TPDHSIESNTGSTQSPTSHSLL..LKFSFCIVYYSYFAIVVlGCVLPFEHTHT---FLIAFLVI--...........FGIISVILFSGSIYYYETWTKT...............VKH---...........-------FLKKVISPFKKEY..IVCAFLKTFVFYGL-LKTIEHFLVLLSGDKWGWKCSTLSSILTPV---sci.........................
WTF13_SCHPO/177-256             ........................................vfl-----------------.---......----------------------------------......---...............................------------------------------..-----------------.------------------------...........-------------------AKC...............VKVTAV...........FLAKCVKVIAVGLYNSKKDL..VVTIWLAWVVICFILFGCVKDGRLNLNKALICSTCSISAALFFILLLV............................
WTF19_SCHPO/203-282             ........................................vfl-----------------.---......----------------------------------......---...............................------------------------------..-----------------.------------------------...........-------------------AQC...............VKVTAV...........FLAQCVKVISIGLFNIRREM..MIIIWLLWLIICCILFGCVKSGDLNLNKALIYSTCTISAVLLLIVSSV............................
#=GC seq_cons                   ...........................................MpNphhsLcSshDE.st..Ks......spEIDLEKG.LPEasSE-tusLPs.S-..hhtss.......sp..........................................sphEpp..hpsspss...L..l+hhluhhsl.lh.hss.hCh..hccuhF...Gthta.hh.............hshsC.lhhIhhhhaaEoWsps...............lKVTsl............LApClKshuhulhp.h+ph..h.hha....lh..h.h...p.......tt.hh.psoh.s.h.h.h...............................
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