#=GF ID   Wap1
#=GF AC   PF16997.9
#=GF DE   Wap1 domain
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   PDB:3zik
#=GF GA   29.10 29.10;
#=GF TC   33.20 37.00;
#=GF NC   27.00 26.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Repeat
#=GF CL   CL0020
#=GF RN   [1]
#=GF RM   23395900
#=GF RT   Structural insights into the regulation of cohesion
#=GF RT   establishment by Wpl1.
#=GF RA   Chatterjee A, Zakian S, Hu XW, Singleton MR;
#=GF RL   EMBO J. 2013;32:677-687.
#=GF DR   INTERPRO; IPR031550;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   The Wap1 domain is found at the C-terminus of fungal Wpl1
#=GF CC   proteins (also known as Rad61). These proteins are members of
#=GF CC   the cohesin complex. The Wap1 domain binds to the ATPase domain
#=GF CC   of Smc3 [1].
#=GF SQ   27
#=GS H2AV63_KAZAF/244-620      AC H2AV63.1
#=GS A0A1G4KG95_9SACH/207-583  AC A0A1G4KG95.1
#=GS J4TY89_SACK1/254-636      AC J4TY89.1
#=GS A0A0C7MZY5_9SACH/217-591  AC A0A0C7MZY5.1
#=GS G8JUV5_ERECY/191-568      AC G8JUV5.1
#=GS A0A1S7HSP4_9SACH/210-571  AC A0A1S7HSP4.1
#=GS G8C0E2_TETPH/267-643      AC G8C0E2.1
#=GS A0A7H9HRL1_9SACH/220-591  AC A0A7H9HRL1.1
#=GS G8ZTM9_TORDC/222-591      AC G8ZTM9.1
#=GS Q75E93_ASHGO/187-561      AC Q75E93.1
#=GS A0A1E5RB61_9ASCO/255-346  AC A0A1E5RB61.1
#=GS A0A1S7HXB4_9SACH/210-572  AC A0A1S7HXB4.1
#=GS A0A4C2E8S7_9SACH/241-602  AC A0A4C2E8S7.1
#=GS G0W4L1_NAUDC/237-398      AC G0W4L1.1
#=GS RAD61_YEAST/253-636       AC Q99359.1
#=GS A0A1G4IU41_9SACH/199-569  AC A0A1G4IU41.1
#=GS A0A1G4MCJ3_LACFM/212-588  AC A0A1G4MCJ3.1
#=GS I2H779_TETBL/266-668      AC I2H779.1
#=GS A0A1E5RB61_9ASCO/370-580  AC A0A1E5RB61.1
#=GS G0V7Z5_NAUCC/235-601      AC G0V7Z5.1
#=GS A0A1X7R502_9SACH/295-685  AC A0A1X7R502.1
#=GS Q6CW44_KLULA/225-578      AC Q6CW44.1
#=GS C5DED4_LACTC/194-575      AC C5DED4.1
#=GS A0A7H9B0H4_ZYGMR/229-599  AC A0A7H9B0H4.1
#=GS A0A376B6T0_9ASCO/245-611  AC A0A376B6T0.1
#=GS A7TN51_VANPO/236-614      AC A7TN51.1
#=GS J7S1P7_KAZNA/201-573      AC J7S1P7.1
H2AV63_KAZAF/244-620                 ..........................................................v-TYHYNELKNMGSSIKYQEDLEFLTFNGSTDMKI....SSF.ASKLLNFIYAIDNDQSFLEYIQKNHESKLLDWCFT......K.....NV.LDIP...ELLVLQGALMYKLNIKLADNNIHKiaNLGA......FLIALSKIE.GI..PNSSKifKSNKLLNLSYQDYLEKRN.iGEDGLFYSIKLWE.RYN...TAF..kGSHPTIKRLLEII-----...-KKGDINIAFLIVLETVLSLVNFR....NERVSINLSKTVGPLVTNFN..GFKENDKYVKNLILLTN....EDTI.LVKIPQGEKNSIFLNSFNFVLSN....INEAE--..............NL.DILLLHLGLCLNVIN..ECD.GSIRN-....LDQLCSTA.GEIIMSNHVRITN.....KLMRGLICLNLTFL..iKLEP.....SNKIDDEMKTQLTHELNIFEE.QTGIFNKSINEKVKLALKKI................................................................
A0A1G4KG95_9SACH/207-583             .....................................................vsntiv------RLKSFGKTLKFDDDLLFIESPLEK-LSQ....GNQ.ISKLLNFALDLSNNSELHAHISKYRLADVWNWCFG......P.....RP.VDMC..yTLKYLKLFIAHTLQPNQDDQLWAV.fPFES......LILDIDRQD.GL..RSDK-..SLKRIAQMNFNDLVSRNN..SASAFYYAQKLWPlAYR...EGI..hLSARVLETLIDVCQNPA-...----NIPDLCFRAVESVVASGV--....REDLLTQYQDLTIVLLAQLE..GHSASESMLKSLIKLTN....DRII.TACLSPDHFAMILKASTKYVIEDa.aaFNSIP-T..............KS.DVLVLHLGLLVNILT..TCA.ERIPAL....DDKAFKCF.FDIFRSLKEDQDA....qDFNSNMFYLVLACL...CIHQ.....GKDCSRTDMKYLRERLTEFAQ.EIKVYNASIYEGTQAALEKL................................................................
J4TY89_SACK1/254-636                 ...........................................................STNHYNELKNMGDTIKYQDDIDFFLSNSKNSVNDsgsiNDY.FKKLLNLSLMIINDDGFFQYARRYFKKEIISLSFF......R.....VE.LDFP...ELMLLQGYLLGKVSESQCD--FPP..SFES......FSIELSRNEgSI..CRKNR..RINKLSHLNFEDFLQETQ..FKTGLYYSLSLWE.MYG...KF-...-SASMIKR-ISIIASNRD...LFNQHVIK-LIPLLEKMMSDSKFGlifiKQPDIFD--GVISNLNNQFK..NMIDNDYFIRTLILLTNmeghNHKL.WESMD-----MIFQDSMNTILKG....IHPLIDA..............KV.DNVLLHLGLCLNLCG..GKN.CDLEVDd.elWHNMRATF.LKMIRDDS-EVEN.....RLMQGLFYLNFAFVv.nQRKE.....GDYLDSWELNTLTVALEAFES.ETSQFNEGISSKIEIALHYL................................................................
A0A0C7MZY5_9SACH/217-591             ...........................................................STQHFNHLRDMGEALKYQDELEFFLHENSKTNSD....-TK.IASLLGLALNMLNDTKMLDYAVKQSQLEIWEWCTG......L.....CA.NSND...LILHVCSFILNAVAVNPKNIASGQ.iNFHE......LVLPLLKQL.SV..VSTD-..ACTDHVKNNYEEFLKLTD..RKPGLFYGLKLWN.LCL...DKS...KSTDDY-NASDTILQALK...-NSQSYASDAFVIALKVLTKSTMH....QK----SRSEWLKALTPFCC..SQATNQDLVKVLVRLTN....DAFE.I----CDGMADVLHCSLAFTLTNsallLQHGQGD..............LI.EVFVLHLGLCLNLAQ.iKSL.VQIVPHs..tVQRTYEVL.QEILECSEQHSQQ.....DFNQNMFVLICCYF...ACSG.....CLTFQPAENDQIQIRLQAFAE.EIEPFNKSIHTNVRQVLDA-i...............................................................
G8JUV5_ERECY/191-568                 ..........................................................e-SQHFNQLRNMGEWVKYQDDLDIVINYEYNSVGD....K--.RAALLSLCLDMINNEKLSQYIVRYRHHEFWKWCFE......F.....TD.PNQK...VLSFLQCFIVDTIPLKNDDSFWRM.iSLEE......FILPLVTEE.SL..PKQI-..AGSRLVKLNYKDFMKVFP..HRSLGNLVLKIWN.RHT...DSI...GTSEIS---IPVFSALLP...TTDIEDTTTILCLIEKNIPASHSP....DTRYKKQYQSLFNLLMSLRN..NVLDKEAILKCFIKLTN....HCHL.L-EMKKDSLTILFQDSVTLLHKLkksfLSTDEDP..............MI.NMLILHLGLCLNVIT..EVP.LTIGTT...qLDSLTKIF.NTIYKNENIKQEL.....SFIHDLFLLVFAYS...IHEY.....KMVIGGCELAYLKTQLSVFAS.DVESYNNSIYERTAYILQRI................................................................
A0A1S7HSP4_9SACH/210-571             ..........................................................q-TYHINELKNMGDNLKYQDDLELLMEGSPTKMSR....PHF.TSNLLSIALTMNADEDFCCYVNEHQAAEMWRWFFS......Q.....RD.WNDP...VLILMQGWLSTIFHLPADD--LPP..FFQS......FVAASYSNN.VL..PHSST..VVTKIAQLNYKDFLQRTR..NSTSQEYALKLCL.QYP...GLL...SSKELVESIVDNFVKKV-...----KSPKSSFPVIERIVSSALV-....-QGVAWA-PTLFNRLVTLLP..AYCNDDSLIKCLILLTN....ERAM.P------KQNLAFKISMEFVLNH....FWPLRLE..............QT.DILILHLGLCLNIIG.sSKE.MSVDDS...qWAQANHTF.SKLSHCHEI--D-.....CFLPNMFYLNFAYM...TVSS.....NKKLQSRTRTKLAEKLNSFAE.EARHYNKSIPDKIKYVSEK-l...............................................................
G8C0E2_TETPH/267-643                 ...........................................................STQHFLELKHIGGTLRFEDDLEFLTSGSPEKLTK....DKF.ISKLLNFSLAIQTDKDLISYINKHCKNEVYEWCFT......K.....AT.VRDP...IIILLLGVICHEIEIPINEHNIDS..HL-T......MLSELSKQH.DI..PEDTT..LTQKLVKLNYKDFVNIIC..PNTGVTYTIKLLE.KNT...SVL...MNQSSCQKITCTLLKNYN...ELQTQDQDLLMKHLQDILSNYKFE....--LN--FLQNVVNSLESIFM..SANGNTEVLKSLILITN....DQEM.VKHIKYQTKQNMYNTCSTHIVNH....FFSRKGS..............II.ELLLLYNGLLLNIIS..QTN.NDLQLSr.etLDNFTKIY.NKLNDETPNESN-.....QFLHDMIYLNFAYLl.rQFQD.....SNLINDTTTSELHSKLKQFNL.SVKEYNINLSRKIEQILN--i...............................................................
A0A7H9HRL1_9SACH/220-591             ...........................................................STHHYKELKNIGEVAKYQDELQFLTDESPFKINI....ETF.ISRFLSLAMAIEQDKEFLEYIIRHAANEVCRWCFS......K.....EF.KSHP...VVTLLQCFLLTKLRLPPED--LPS..DFNS......LIVVSLDCD.KP..PSIQT..LTGKLRRLNLADFLNKTG..RKSAQDYSLQLCL.DYP...EQL...TLQEVMRRIFDIA-THRD...L-DLESSSVLFPLVEHILSSGSPI...vGDSS--KANILLSSLICALP..KQCCNEDLVKSLIMLSN....KNEV.LAEAPVEQKQKLMHYSLDFILRH....IHPIKES..............TA.DLVILYLGLLLNMLD..VCD.AQVFEKe..qLDRARKLL.LSISN---S-DTD.....PFIVCMYSLNLAHI...LFGA.....GEQPHQEEKDLLMKILNSYDK.EVMNTNQVIRDQIRTALN--nf..............................................................
G8ZTM9_TORDC/222-591                 ...........................................................STHHYNELKNMGESLKYQDDLGFLTEKSPSKLDT....DSF.TSRLLNLALTLKQDEDFLLYVDKHCAIDVCSWSLA......K.....KA.LDHP...VTTMLQAFLLAKIDLPQESLPFLS..--EK......LIVALLSAD.KV..PPKSA..LHSKMTRLNFIDFLKRTD..HTTGQVYALELCL.KYR...NIL...KSEDISRRVIRLIEEN--...-KNPQLRVLLHPLADCILTQDTTI....LQ-DFTQGSSLLSNLVAALP..QECNDEFLIKSLILLSN....EHKI.ITQASKDDKTKIMNCSLDFVLDN....VRAEKSD..............NL.DMVILHLGLILNLVD..ACD.WQID--....ASRLELAR.DMLYKNMNTGNT-.....EFMVFMLSLALTHL...LHRS.....GVLLPRDEKNLLTKILKPFDS.EAKNCNESIRIKVTTALNYL................................................................
Q75E93_ASHGO/187-561                 ..........................................................l-SRHFNELRTMGETLKYSEDLDFILSDNSMTTPE....H-R.RNNMLRLCLDMMNNEDLCQYIVKYRHREVWEWCFQ......G.....TD.PKQK...VTSLLQCFIADKIPLLRHDKRWAM.lSLEN......FILPLATDE.VF..PKKI-..AGSRLVKLNYQDLLRKLK..FTNTCEYALYIWA.TYL...---...LYTEAVYGAVPALARLIS...RGQLKDWDTACSLLENNIVAAP--....SGSDIEEYAQAFQTLAGLSR..EKLTNEGVLKCLIKLTN....HTTV.L-ELSADLLPSLVRSLAMSVQLHqnniVSSISEI..............KT.NLLILQLGLLLNIVS..EAT.TAASTE...eLTNFGAVF.RSVFVKKPTEM--.....SFVLQLFLLVYAYS...AGAA.....GVQLPPAEADFLKSELEAFAT.DVSSYNHNIHTRITRVLETL................................................................
A0A1E5RB61_9ASCO/255-346             ..........................................................l-TQNFNQLKAMGSNIQYNDDIRFVMEGSLPA---....---.VKKFITMIQEVRSSEGLRNYIANYYTDEFWDLL--......Q.....NN.ADDP...YLLMVLST----------------..----......---------.--..-----..------------------..-------------.---...---...------------------...------------------------....--------------------..-----------------....----.-----------------------....-------..............--.---------------..---.------....--------.-------------.....--------------...----.....---------------------.--------------------lgrmhsklaighf...................................................
A0A1S7HXB4_9SACH/210-572             ..........................................................q-TYHINELKNMGDILKYQDDLELLMEGSPTKMSR....PNF.TSNLLSVALTINADEDFCCYVNERQVADMWRWFFS......Q.....KD.WNDP...VLMLMQGFLSTKFHLPADD--LPP..FFPS......FVAALYSNN.VL..PHSST..VATKIAQLNYKDFLQGTR..NRKSQEYALKLCL.QYP...GLL...SSKELVESIVDNFVKKV-...----QSPKSSFPVIEHIVSKNAL-....VQGV-ARAPTLFNSLVALLP..AYCNDDSLIKCLILLTN....ERAM.P------QPNLAFKVSMEFVLNH....FWPLPIE..............QT.DILILHLGLCLNIIG.nSKE.MSVDDS...qWAQANHAF.SKLSHCHEI--D-.....CFLLNMFSLNFAYM...TVTL.....NKQLQSRTKAKLAEKLKSFAE.EAQHYNKSIPDKINYVSE--kl..............................................................
A0A4C2E8S7_9SACH/241-602             ..........................................................q-TYHINELRNMGDMLQYQDDLELLLEASPSQMSR....VQF.VSHLLNIALAMNGDQEFCSYVNKRQARDMWRRTFH......Q.....VD.LLDD...LLLLIQGFLVTKFQLPPNE--LPP..FFNE......FVRTLCKQK.QL..PVNGF..SGNKIAQLNYNDFLQGSE..GRIGQEYALELCV.QYP...VIL..lSCSSLIDQIVQILV----...-ESENLPRGIFPVIEQIASRRDTV....QDSNLVS--IISNKLIDFLP..NNCYDDHLIKALILFTN....EGMF.E------KNNEVFHISMEFVLNH....LPPFG--..............ST.DILILHLGLSLNVIS..SED.GVLHLEn.slWSKANAIF.HKLEYNDD----Y.....SFLLNMFYLNFAYM...TVLL.....DKRLSTRVKTDLISHLKNFGE.ESQNYNGSISNKIKYITDK-l...............................................................
G0W4L1_NAUDC/237-398                 .........................................................dl--THFNELKNMGTSLKYRDDLDFLQRKEMGT---....IEY.ISALVNFCITLHTDEDFKKIVMELDIDTIRDWCFE......SypeglQS.STLE...IIYLLQGYLITTLGVLGKEEETNN.qQLQN......LLNGLPKLK.AL..PDLSI.lNKHKMLKLQLNDFIQFTD..GTTGYDYSLRTMK.K--...---...------------------...------------------------....--------------------..-----------------....----.-----------------------....-------..............--.---------------..---.------....--------.-------------.....--------------...----.....---------------------.--------------------ser.............................................................
RAD61_YEAST/253-636                  ...........................................................STNHYNELKNMGDTIKYQDDIEFLLSNSKSNDNTtvpiNEY.FKKLLNLSLMIINDEEFFQYAKRYFKKEIIKLSFA......Q.....FR.SDFP...ELILLQGYLLHKVSESQSD--FPP..SFDN......FSIELSKDDgKI.rTKKNK..HIKKLSHLNFEDFLRKTQ..FKTGLYYSLSLWE.MHG...N--...LSLDIIKR-ISILASNKD...LFSRHVKT-FIPLLEKLITASEFChmyiEQPEMFD--SLISNLNNQFK..DMLDDDSLIKILILLTNmevhNYTL.WKEAD-----MIFQSSMNTILES....IHPLTDA..............KV.DNILLHLGLCLNICS..REN.SRLKLDg.klWYDMKTIF.VKMIRDGSDTE-N.....RLVQGLFYLNFSFLi.kQRKE.....NSNLDPGELNLLLVELEAFKS.ETSQFNEGISNKIEIALNYL................................................................
A0A1G4IU41_9SACH/199-569             ...........................................................STQHFNQLKSTGETLGYQDELEFMLQRDATMTAP...aK--.RSRLLDVALAFLKSPEMLEYAIKHHQTEVCESVLD......L.....CS.FENY...TFVHVGGFVLSQLRLQPDNSLWNS.iGLRN......LLLQLVHPEsDY..TDRA-..-VTEVLLSRYNEFLQLVG..STSGLLYGLKLWN.VSL...D--...HHDVVDSRECDIAIRLLE...-ENCSYPHDLFKVAEKILCKSSS-....---QAVPLSRWFEALVSWFP..AHITDDGLVKALVKATN....DNTQ.L---QGRGAEKVFEASLSFLLEY....LHSAQNL..............E-.DVVVLHLGLCLNVIQ.iQGV.LQVALGe.kmLDRLYCML.KDLHKLSDKGCAY.....KFKHNMYLLICCYI...SLHQ.....SLSFQLAERKFVETQLKAFAS.EVKLYNTSIYASICTVLESI................................................................
A0A1G4MCJ3_LACFM/212-588             ..........................................................a-THHFNQLKVMGESLKFQDELEFLMSDADKD--I....QSF.ISRLLTLSLDILNNDELRAYIIKYQHKDVWNWCFK......V.....SD.PHNA...VLLYVQAIIATIIPLDDRQNLWYR.lDIDD......FILPLTSQK.IV..IENI-..EGTKFMQLNYRDLLAKTE..RRTGLYYALTLWP.KCQ...DPD..cELSEIQY---STLVNLLK...-DRTEWIDMLLEVVEVIIPNEFP-....MK-LSKRCIDLFNILSQILE..QLTENETLIKSLIKLTN....NRTI.IASLPTEQRIGLLKLSLSYIANSasvfESQSSSS..............DS.GLAILHLGLALNLIV.dLKD.ATLRIEy.dvLQELKRKY.HKILSRIAN---F.....NFGENMYLLVFAYV...CKIA.....NITLDSVANVDVYQKLHDFSN.EVKMYNKSIYFGIRALLDTI................................................................
I2H779_TETBL/266-668                 ...........................................................KTFHYSELKNMGDTLKYQDELEFLSLDTNDMSLK....ENFvINKFVNLALLLNSEVDFFAYVQKYKATDIWEWCFP......K.....NRiFSDP...VLILLQGFFASTL-FNENFGATPS..YFSN......FLIKLQKQV.RI..PKLQS..DLSKMACLNFQDFLNFTN..NKLGIDYSFEIFS.KYK...RDIlidNSQAVLSSCIDYISRIVD...IEELSNLEAIFQVLNILLENDIKN....MEITNVEKLKIIDFLMKLMN.tEYINTMDFNKCLILLTN....DEEL.I--IENSTRNEIVNHCFKYFIAS....IDIINDAtrntsedykllpllDI.NVLILKLGLCLNVVS..SSQ.ISLDIHcessWSDLTILM.HSISTTNPSKSDNlepqvEFIYNMILLNVAYLy.iKQNN.....DEHLKKKDLNLIVVSLKKFYE.DTNDYNESIHLKIKK-----l...............................................................
A0A1E5RB61_9ASCO/370-580             fkvfgnhttlgvktlnxlkekkqaiiedpritdylaripfcpeiisllpfvdldknaks----------------------------------....---.-----------------------------------......-.....--.----...------------------------..----......---------.--..-----..------------------..-------------.---...---...------------------...------------------------....-----------FWKLTTNINiqNNIENADYIKSCVSLTN....TRNF.D----TRNVTNLLNFSLQYILTN....FQDTDKQ..............H-.-LLILHLGLCSNILH..LHK.KKVLKV....SYDLSPIY.ENLDMAK-----L.....DFVHNLFLLNYAYL...LKFA.....GKEIDT----SITKSLLCWAT.NIDDLNNSFKERADYILN--s...............................................................
G0V7Z5_NAUCC/235-601                 ..........................................................a-THHYNDLKNMGTDLKYENDLDFLTRKRLSSI--....-DL.ASELLHLCLNLENDDQFRMFILEHHSEDIWRWSLTcfrtilE.....EN.YNHEflsVLLLLQGYILSTLPLDTDS--LPE..EIDM......FISALYDQS.EL..PPRSI.fKGRNLLLKNYDDFLEKTS..SRTSLYYYFSLWK.QYYlakDHF..tSGLPMFFRCYAM-EFEKR...GLEGDGEIDITEFAELLLSLLMS-....KKRSAISKKDFLDLFKILSL..HMCDDEALLKCLILMTN....DNYLgLEDVPTDTLYTMSQKTIELLVRQ....LKNEGDI..............EAgDQIPLLLCLYFNIIK..YLK.I-----....--------.-------------.....--------------...----.....---------------------.--------------------pdehkeacekffnesispllnkefvhewsdspetsqmffiiavlysdilgvkiplkqkeiiqad
A0A1X7R502_9SACH/295-685             ...........................................................KTYTFNELKNIGNSLKYQEDYDYLTNTLQKSTSL....SST.ISILSEFILAISGDDEFLLYIAKHHSDDICKWCLQ......Q.....DP.SNNQ...ELLLLQGYILNLFHKSSDFFNKME..NVKQ......VLLNLGKCV.TV..SVGLK..TNSKMQKLMYLDFLKING..ESSGLNYALNIWN.THI...TKF...PTEY-IAKVLRLLMKISDnqeKTKYMCCSSYFSLLQTVLDALKDNdlegDDI-DTEKREICKMLT-NNN..DLINNDEYLKCLVIATN....DRSS.TAIIDHKTVDDIMEVILHSIIRH....LKGRSEG..............ND.DNIILQLGVCLNTLN..DCR.TDINIPd.ttWYRLKNLI.--LQNDIHE-VHT.....PIIQNLLYLNFAFLtiiKTNKnvsagESLLSDTEKMQLTNALDLFKL.DASNINKFVDEKIMHAI---mev.............................................................
Q6CW44_KLULA/225-578                 ..........................................................s-VIHVNQLKTLGEGLKFEDDLDFLPFTTSDE---....KLF.VVKLISCCLLLLNNTELTSYTQKYKSNEVWNWFLQ......Q.....IN.PENN...VMSYLQLWIANLVPLPRSAPQWQQ..----......LSPLLMTCS.SL..TENPKliEGSKITKLNYTDFVQRAE..-TNPQDLTFTLWE.FHL...D--...PNSNEFSKLIESLNNPTP...R--------LFVLVEQHLDKFIT-....EEMMTNLYPKMLYYLS----..SYIEDICTIKIMVKLTN....HAFF.LSLLSPLEKVKIVRACLSYIIKVr.ekIESEQDT..............D-.DIVILQLGLVLNIVA..KDT.IKIE--....----NSIT.QQIQDMIGQSKSE.....SFLKQLLALVFVLH...TNTT.....EWNHDLSTTASITKLLKNLSN.DMKDTNETIYNNVQTALTIL................................................................
C5DED4_LACTC/194-575                 ...........................................................STHHFNHLKTMGESLKYQDDLEFMMQKEAQMTLA...aK--.TSNLLIFVLNLINNAGFFEYVMKYSRKEIWQWCLH......L.....GN.CEDP...VLRHLCAFIYSKLPLDADDPMWGE.lNLYE......FVLPLTSQK.SG..TLKI-..KGSKFTEMSYLEFLNATE..SKPGLYYALLLWP.PFL...G--...HQKEIDQNVVDAFTALLQ...-NSCEYVDTILPIVEKLVSKETV-....-EGHSTSYKNMMQALVPLFE..PHARNDSLIKALVKMTN....ESTL.VAELKDGQKTVLLTNSLEFLLAYdrflFDEQESE..............LL.DIFVLYLGLALNLVKalKQD.DAVFEDknplMERLKRTF.QDLQAASDESNQH.....NFNQNIFILIYCYI...AMHY.....KVRLQEAERAFVIPRLEAFSQ.EIKRYNESIYTAIAVILT--p...............................................................
A0A7H9B0H4_ZYGMR/229-599             ..........................................................t-THHFNDLKNMGDFLKYQDDLEFLTAEPSINMEI....IVF.TSKLLNLSLAIRDDEAFLLYILRNNLPRTIKWSFP......K.....IL.-QDP...VVLLLQGYLLTRLASNSND--LPD..IFHD......SVFLMLSQT.MV..PDCSL..IGHKMTRLNFTDFLKQTN..DEPAQAYALKLYL.MHP...TVL...SSSGFARKIFNLV-----...-GQKKNANLIFQSIETLLTTETKH....-HIE-QNQKEALLLLQKLIRhpEFEKDENYVKSMILLTN....GTSI.LSMLPVQEKIHAYTQSIEFVLLH....MEVESGS..............MF.DIRLLHLGLALNIIT..QCEdIEPQES...qWVRARKTL.QNADQNGSNEIE-.....RFAVHMLYLNLAYM...IHRL.....QKSVSGRERTSIISMLKRFDE.ETANYNENIHEKINVALHKL................................................................
A0A376B6T0_9ASCO/245-611             ...........................................................STQDFNQLINMGTDLQFNDDINFILEKQCE----....--F.HEKMISLILAIANSPYLKKYIIRYKYKDILGWCFK......N.....KD.KKFL...FLQVLLAFLIG-LQASPNDTFWDS..AFGVedycylLGNKINNIE.EY.fVHEKL..ELSKYGGLDFADLLNTLRtdETDIKYLILKVLN.VTR..pENI..vNNLKIQNALANIFMVNS-...-DKDKYTEMIFPLLDPK-------....------YYSLFLQYLVDNFN..KYKENEQYLKLLVKVSN....ECNN.F-EIV-----RLTKLSLQYICEQ....GCNIHED..............KM.DLVILHLGICLNILS..GTG.KRIQVEd.idIKSILKLFdSQIFKQMDRQDSN.....FFIENLFILVFSYI...VLLC.....EIQLEVTKIDFIKEQLRIFAStDIGMQNQSIEHHIQHILEVL................................................................
A7TN51_VANPO/236-614                 ...........................................................KTHHYNELKNMGNMLRFQDDLEFITEESPQEISK....ESF.ISKLLNLSLTMNSDEAFLAYINKHSNKDIYQWCFQ......R.....DE.FDNP...LVLLLLGFITSKLPISQDL--LPA..NFDK......FIRRLSLQE.KL..PPVTI..AGKKMVQLNYKDFLTKTN..NNTCLTYSTLLWK.NYG...KNL..fKSSNVIVDICKVLNRYNN...CENEDIIVAILALIETIASTGCLD....LETTR----ESLDILIPLLD..ERINNETYIKVLILLSN....SSES.LTSITNNNKSKVVNKTLPFIARN....ILPLSKD..............KV.DLVILNLALSLNFIS..EGD.SRLSLDe.siVSRYKEIF.NRVTSLVRTREQEn...hTFLFNMFFLNFTYI...SKIA.....NISLTQEERDVLIQKLHEFHN.VTIKYNENLLKKIDDALDMI................................................................
J7S1P7_KAZNA/201-573                 ..........................................................g-ANSFHELRNLGHSLKYRQDLEFLLTDCISH---....---.AERLLNVNLSIRRDNLFKEYLSKHHANDIWGLCFN......E.....DA.-PSP...ELDFLKGTLLSELKLRPTEIRSWP..TFSQ......LITRLSNNYsKPngPAKNKkkKTSKMVLMNYNEFYSKSH..FDTSLDLALDLLQ.YYH...KEV..sLGSELQRNILVFVSEHP-...-EREDTLVKTYSTLSNILLDCTI-....NDSSTFN--FLLEVFTKNLP..TGYANPYYSQGFILLTNrlleEFKM.TPQLADQIALPTFSLIVADLLDG....ESTIEQQ..............KT.N--VCQLALCLNVLD..YCD.IGIKIE...qWSKVPQIL.SGLQKQGAD----.....KFLVGLFALTVSLVs.iKSLS.....VHPTTPSLQELLRQELHSL-K.IIAKDNKSVSSKVEYALGKL................................................................
#=GC seq_cons                        ............................................................TpHaN-LKNMGcsLKYQDDL-Flhppsspph.......ph.hu+LLslsLslts-pchhpYl.+aptp-lhcWsFp......p.....ps..sps...llhhLQualhspltlstss..hs...thpp......hlhtL.ppp.pl..sppph..tssKhspLNapDFLptsp..tpsuh.YuLpLh..hah...p......spphhpphhshh.p........p.p..p.hh.llEpllspth.......p....ph.phhphLhs.h...phhss-shlKsLIhLTN....cpph.h..h..tph.tlhphShpallpp....hpshppt..............ph.DlllLaLGLsLNlls..pps.hplp.p....hpphpphh.ppl.pp.tp..p......pFh.shahLshuah...thtt.....shplpttpts.lhppLctFsp.-sppaNpuI.p+lphhLp..................................................................
//