#=GF ID   WipA_Phos
#=GF AC   PF21663.1
#=GF DE   WipA-like, phosphatase domain
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   PDB:5n6x
#=GF GA   27.00 27.00;
#=GF TC   27.70 65.40;
#=GF NC   26.20 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0163
#=GF RN   [1]
#=GF RM   28389563
#=GF RT   Structure of the WipA protein reveals a novel tyrosine protein
#=GF RT   phosphatase effector from Legionella pneumophila.
#=GF RA   Pinotsis N, Waksman G;
#=GF RL   J Biol Chem. 2017;292:9240-9251.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the phosphatase domain of WipA protein
#=GF CC   from Legionella pneumophila. WipA is one of the effector
#=GF CC   proteins involved in pathogenesis and targets
#=GF CC   tyrosine-phosphorylated peptides [1].
#=GF SQ   43
#=GS A0A0W1AF36_9GAMM/91-326   AC A0A0W1AF36.1
#=GS Q5ZS02_LEGPH/174-414      AC Q5ZS02.1
#=GS A0A0Q9YVC9_9COXI/97-329   AC A0A0Q9YVC9.1
#=GS A0A0W0ZP74_9GAMM/173-413  AC A0A0W0ZP74.1
#=GS A0A6F8T696_9GAMM/105-340  AC A0A6F8T696.1
#=GS A0A0Q9YMH0_9COXI/104-351  AC A0A0Q9YMH0.1
#=GS Q5ZXT9_LEGPH/112-349      AC Q5ZXT9.1
#=GS A0A0W0R2K1_9GAMM/1-203    AC A0A0W0R2K1.1
#=GS A0A0W0YW58_LEGSP/118-350  AC A0A0W0YW58.1
#=GS A0A222P0C8_9GAMM/403-472  AC A0A222P0C8.1
#=GS A0A0W0YW29_LEGSP/91-332   AC A0A0W0YW29.1
#=GS A0A0W0YK43_9GAMM/99-333   AC A0A0W0YK43.1
#=GS G9ET76_9GAMM/96-325       AC G9ET76.1
#=GS A0A098FZJ1_9GAMM/89-318   AC A0A098FZJ1.1
#=GS A0A433JKB9_9GAMM/125-368  AC A0A433JKB9.1
#=GS A0A433JXG4_9GAMM/2-179    AC A0A433JXG4.1
#=GS A0A0W0UA42_9GAMM/93-332   AC A0A0W0UA42.1
#=GS A0A078KVK6_9GAMM/89-326   AC A0A078KVK6.1
#=GS A0A562BPH6_9BURK/354-553  AC A0A562BPH6.1
#=GS A0A0W0YWB7_LEGSP/174-413  AC A0A0W0YWB7.1
#=GS A0A433JZH1_9GAMM/89-253   AC A0A433JZH1.1
#=GS A0A0Q9YWU8_9COXI/97-330   AC A0A0Q9YWU8.1
#=GS A0A222P2C2_9GAMM/173-413  AC A0A222P2C2.1
#=GS A0A378LXA9_9GAMM/174-414  AC A0A378LXA9.1
#=GS A0A0W0XML5_9GAMM/101-356  AC A0A0W0XML5.1
#=GS G9ELX3_9GAMM/244-487      AC G9ELX3.1
#=GS A0A0Q9YLZ8_9COXI/95-330   AC A0A0Q9YLZ8.1
#=GS A0A0W0VKN1_9GAMM/96-328   AC A0A0W0VKN1.1
#=GS A0A098G1U2_9GAMM/105-340  AC A0A098G1U2.1
#=GS A0A222P0C8_9GAMM/473-677  AC A0A222P0C8.1
#=GS A0A098GHV7_TATMI/89-326   AC A0A098GHV7.1
#=GS A0A0W0YZY7_9GAMM/174-414  AC A0A0W0YZY7.1
#=GS A0A7J6YQY5_9COLE/94-330   AC A0A7J6YQY5.1
#=GS A0A0Q9YIT3_9COXI/96-329   AC A0A0Q9YIT3.1
#=GS A0A0W0VU49_9GAMM/106-346  AC A0A0W0VU49.1
#=GS A0A0W0YKU0_9GAMM/118-350  AC A0A0W0YKU0.1
#=GS A0A0W0VDA6_9GAMM/93-336   AC A0A0W0VDA6.1
#=GS A0A0W0W3D7_9GAMM/89-318   AC A0A0W0W3D7.1
#=GS A0A078KVF6_9GAMM/117-354  AC A0A078KVF6.1
#=GS W0BDF9_9GAMM/93-330       AC W0BDF9.1
#=GS A0A0W0YLA9_9GAMM/174-414  AC A0A0W0YLA9.1
#=GS Q5ZTF6_LEGPH/118-350      AC Q5ZTF6.1
#=GS A0A5E4PEX0_9COXI/92-253   AC A0A5E4PEX0.1
A0A0W1AF36_9GAMM/91-326              ...........LIRLIGDEVCDRGENDYFIFKILD..KLKKS..GVAVEILLSNHGIEFLIPYEEQKht.ldV.NNLFA...PN-.IN.FG.GQAQSMNNLRNSIECG...IIRANEVNSLIKDSYL........PCLKLISYTLS.G..SV...ITIYSHAGVGLETIRALAE.....................KFkdkG...VVYQD..DT.AEQLAKTIEAINWVF.AQHVRTGTVHTLPVDLA-----...--KSCDFRDDPVNFLLWNRDYTE....-LSRNQEHNG......YTLFYVHGHDSGEK.......T.HENIVNLDGYLGK............................................
Q5ZS02_LEGPH/174-414                 ...........LIRLLGDEVADRGSCDYFTLRILD..FLYQN..QIAIKIILSNHGYEFIHAYEKLV.....V.GQPFK...PKG.YI.GD.IQIKSFWGLQLLLEQS...VITEEELRSLVERAYK........PTLKIIDYSLS.E..DG...ITLYSHAPIRFDSIRMAAS.....................QL...G...VTYND..ST.KEALAETIDQLNAQL.QIYMKNNMLHLLFENNEINDPT...NMTDEERNASPLIYLVWNRWNESk.evENARPGKYNG......YFVTYVHGHDPFQS.......P.LTYVYNLDTLCGK............................................
A0A0Q9YVC9_9COXI/97-329              ...........LLRLIGDVLADRGANDYFTLKLLK..KLHDN..GISVVNMISNHDAEFIRCYEKD-.....-.-KHFD...K-T.PL.RE.GQANSADNFQKLMNAG...LIEAAELDELM-KAYK........SSLRVVDYSLN.EarDK...ITIYSHGLIGLQNINYMAQ.....................AL...GideVTCDE..HTsATEIAGVIDKINTKF.KKYVQKDKITDLLQIKKARAGE...GRHTMDAKAYPFAHLVWNREAEG....-LNRPEH---......--INFVHGHDIHDK.......T.AKNIYNLDNTLGK............................................
A0A0W0ZP74_9GAMM/173-413             ...........IVRLLGDEIADRGNCDYFTLRILN..LLHRN..HCPLTILVSNHGSEFIYAYEQLI.....A.GHPFA...PPG.YI.GD.FQTPSFFGLKLLLAQE...IIPHSELIHLVNESYK........PTLKILDYTIS.A..KG...VTLFSHAPIRFDALQLMAK.....................SL...G...VNYDD..ST.SEALAITIDQMNHQF.QSYVESNTIHSLFHTDAIHDKT...NMSAQERAAWPLIYFFWNRWDETk.etETARPATHNG......YTINYVHGHDGFQS.......A.LAHIYNLDTLCGK............................................
A0A6F8T696_9GAMM/105-340             ..........t-LRCFGDMLADRGSNDVLSLLILL..EMRLAfpELRGVILLSNHDKCLLSNYLRGA.....L.--APG...EKL.TM.EL.SPCNSLTRLKWLIDNH...IISYEEVGDMIQKAYL........PALKLVDYVRK.E..DG..sIDIMGHAPLTLRAIDKAMH.....................EFl.pS...NHHKDiyAS.VDDVVYVLDQLNIMF.SKDLTDKESPIYQ---------...ALTTLPSGTNPIYNFIWPRLTDI....--GPEIKVPS......YNYRFRHGHDGS--.......-.-------------pgeikihgvtyigynsifgk........................
A0A0Q9YMH0_9COXI/104-351             .........ff--QMVGDEAGDRGKCDLFVWLLME..KMVDA..KILKNVSISNHTIEPLKLYERGLnfqcgY.GFPSE...EQS.LL.MY.EHACSMQNLQVLIDSEnfpNITRPYVDNLIKKIYE........PTLRLFFYNLN.E..KGd.eITFFSHAGVGLETIEEEAL.....................KF...N...VPFKD..GS.AKELAQTIDNINKHFtENYVEQKRMHELFPAEEMSRLY...--SGYVKTDNPFVRSIWNRIYDE...nYIKRPAIHNG......FKINYAHGHDSGSP.......N.LEHCFNIDNSFGK............................................
Q5ZXT9_LEGPH/112-349                 ...........LIRLIGDELVDRGVIDYFILKLLQ..ALYDQ..GADFEILLSNHGIEFVEACELFK.....EnGNKLV...AKR.LG.NI.QHGNSFHALQEAIAAG...AISNEEVLNIYHQVYK........KHLKIISYSLD.PdaNE...IKVFSHAGIGLNHIRGLAR.....................KF...K...VPYSE..ES.AVDLAKTIDAINKKF.AEKASSGEIHTLYTHDMMYRGY...AGEHLNSTDEVVAATVWGREYGD....-LIRTS--KK......FKITFIHGHDSYDP.......E.KVEHVTLNNQLG-q...........................................
A0A0W0R2K1_9GAMM/1-203               ...........------------------------..-----..---MEIIVSNHSIEFIEAYEKQ-.....-.-DNFH...APM.LS.QG.GHAPSMEKLQTLVEKG...LVSREEILAIAEKSYK........PNLRAISYSLS.E..DKk.eITIYSHAGIGLNTIRSLAE.....................KL...K...VEYKD..QT.ASELAQTIDSINIEF.QKHVKSNTVNTLYSREKMYVGY...Y-GYSEISDAPLEFIMWNRFYHS....-LERPASYSG......YKINFVHGHDSHDP.......T.RENIYNLDNALGK............................................
A0A0W0YW58_LEGSP/118-350             ..........k-IRFLGDDLCDRGMNDYYTLSIYK..KLDTA..GVAFDIVLSNHGHFFLTALERDE.....P.SFDYN...PYG.EGrHE.STVRSMLNMGKLIARG...LVDKRDILDTIQTQYL........KHLVLPGYVLN.E..KKq.eITIYSHAPLDLAMLAALAE.....................DL...N...LPFRD..SD.LKSLAESFDGINRQI.HQWIMAHTLTAHYRELK-----...EKHEEQGRSSPLADVLWNRNYTI...lEREHHPKGKA......YSVSYVHGHDST--.......-.-SNVFDLDNVFGK............................................
A0A222P0C8_9GAMM/403-472             ...........LIRLVGDDFADRGRNDFFTMLLLN..KLASV..KIQVKSLASNHTIEFIEAIEKEL.....K.RRENE...---.--.--.----------------...----------------........-----------.-..--...-------------------.....................--...-...-----..--.---------------.----------------------...-----------------------....----------......--------------.......-.-------------kalpaqaitgre................................
A0A0W0YW29_LEGSP/91-332              ...........-ILLLGDVLSDRGNNDGFTVCLLR..RLHRS..NISYSILEGNHDFEFLESYENGG....nY.RNTYY...TST.RI.KR.GQTSSIHNLQRLLEKD...LRDEKGRFALSRKRFRdwvtyyliDHYKALDYSLG.E..TG...IIIYSHAPIDIGIIAGIAK.....................RL...H...VEFDD..GS.PVTLAQTIDRINVKF.SSLLRRRKLSGKFHAMHT----...TRDKTSRHVDALTRLIWNRDYIS....-LNRSSIHKG......YHIGYCHGHDSKGD.......PdCGNVICLDKMLGK............................................
A0A0W0YK43_9GAMM/99-333              ...........LVRLIGDEICDRGQNDYFIFKILK..KLKQS..GIPYEILLSNHSIEFLIAYEYLIg...nD.VTNLG...APN.IN.FS.GQAKSLNNMRMLIQEG...LITREEIDELVKDVYK........PGLRLLSYSIS.G..ND...ITLYSHAGIDLKTIRYMAL.....................KFrqyG...VVYQD..GS.IEELARTIDAINEVF.AEHVRLGMVHQLPVNLTL----...---RPNAKDDPITFALWNREYSE....-LKRNKQHKG......YNVFYVHGHDSQEP.......T.HENIINLDGVLAK............................................
G9ET76_9GAMM/96-325                  ..........t-IRLIGDELGDRGLGDHYTLMVLN..KLHQA..KTPLEILYSNHGGAFIDYSEMDAt..alE.NINFA...EDF.SL.GDpQQMESLINMHKLISKG...LVSREKIMNSADKAYK........PALKALSYSLS.E..DGk.eISIYSHAPIGMNNIEELTK.....................QF...N...TEYKG..TT.AIELAETIDAINEKF.QEAVKSKRVQQASS--------...-------PNSELYNLAWNTQTGS...lVRPKTLTAEG......DMIKFVHGHCGGRP.......L.DSHIINLDNNLGK............................................
A0A098FZJ1_9GAMM/89-318              ...........LVRLIGDEICDRGQNDYFIFKILQ..KLKKH..GVPVEIMLSNHGIEFLIPYEQG-.....-.HELYA...P-N.ID.LA.GQARSLNNLRQLITDG...VIDKQEVDELVAEAYL........PNLKLISYSLE.A..NN...ITIYSHAGIGLEVIESLAR.....................KFkddG...VVYKD..DT.AEDLARTIDAINAVF.AKHIAAGTVHTLPVHLT-----...--SASDPQGDPISFLLWNRFYHG....-LNRNKEHKG......YNVYYVHGHDSGEL.......S.HDNIFNLDSSLGK............................................
A0A433JKB9_9GAMM/125-368             ...........LLRLLGDEVGDRGANDYFILKILE..KLRKA..SVPYEILISNHALGLIEAYELA-.....-.-QRFE...YP-.SL.GM.DQARSLYNLQKLIDYN...LITRNQVVNLINYAYK........PALKALSYSLD.H.aNN..tITLYSHAPVDLTIIKFLTEkfnek...........yqkdlRL...G...ITYQD..ES.IEELAGTIECINKEY.TMHAELNFIHILYDRESI--GC...DPYAKPNAQNPFEMLTWNRDYEQ....-IQRATKHKG......YNIHYVHGHDATGV.......TdECSYWNLDNTLGK............................................
A0A433JXG4_9GAMM/2-179               .......lsrg------------------------..-----..-----------------------.....-.-----...---.--.--.GHAPSLEKLQEIIERG...LVSREEVIQLANRAYK........PSLKAISYSLN.E..DQt.nITLYSHAAVGINTIKLVAE.....................KL...G...LPYAD..GT.ALQLAQTIDSINELF.QAYVDADAVHYLYEREQMENGY...--MGYVEPHAAFEMLMWNRHYNE...eRIQRPDKIGD......YTLNYVHGHDSNDP.......K.LTNNYNIDNNLGK............................................
A0A0W0UA42_9GAMM/93-332              ...........LVRLIGDETADRGQNDYFTLKILE..KLHQE..KVPVTILLSNHGVEFVEAYERYI.....EqNKKFK...S--.TM.LN.HFAMSLIMMQSLIERG...LIDGDEVIELANARYK........PMLKALDYSLS.A..DGs.eITLFSHAGIDLLIVQCLAE.....................KL...G...TVYND..AT.AADLAASIDAINAVF.SIHVQNNSVHTLYDRSSISQGG..hGGSPIDKTEHPLEFIMWNRFYEK....TLAREETLRP......YRINYVHGHDRGDL.......S.RNNIYNLDNILGK............................................
A0A078KVK6_9GAMM/89-326              ..........a-LTLIGDDLADRGQNDYFTLLVLQ..KLQLE..GINLEVLLSNHGVEFIQDYERE-.....-.--QFS...GHY.DL.GA.GQGESLWNMYYLIRQN...LVDEHEIRTIVEQSYR........PLIKALNYTVSlP..NE...LTLFSHAPIGLETVKAIAE.....................KF...N...LPYLD..TH.LSDLIKTIEAINSLI.QQVLKQNKLARLIKAEGSA---...DLRFPIPLIIPLQRLIWNRALGN...eLVTRPA--GH......FKVRFVHGHVGPQSilkngheV.LPDHENLDNLFGK............................................
A0A562BPH6_9BURK/354-553             ..........l--VLLGDLLADRRHNDLYLLAVLD..RLHDG..GLAYDITLSNHDAQFIHYLASNNg..vpE.DRPYQ...LRGiSI.GP.AQTVSLQRLNELMNQD...PSLRRELRDMASRAYF........GHLKAVSTTT-.-..DG...RKFYAHAVVNESIFTDLCR.....................QA...G...ISEAQ..--.--PGVAAVQQINAWF.QGLL------------------...-----------------------....----------......--------------.......-.-------------stpaayaaamtellpngsptalfaccwnvgvgddryrnsdaeya
A0A0W0YWB7_LEGSP/174-413             ...........LIRLLGDEVSDRGFCDYFTLKILD..FLHQN..QIKKHDTISNHGCEFIYAYEKFL.....Q.GDEWK...PMG.NI.PD.FQITSFWGLKILLEQG...IVTVNELNQLI-DGYK........SDLKIIDYTIS.E..EG...ITLFSHAPIRLDTIQLLAS.....................RL...G...VVYDD..AT.KEGLAETIEQINNQF.QSYINNNIIHTLFHNDQIADKT...NMSEEERAAYPLIYLIWNRWNQDk.etSDARPQCHNG......YTVTYVHGHDSFQS.......R.LPYVHNLDTLCGK............................................
A0A433JZH1_9GAMM/89-253              ..........a-VTLIGDELADRGNNDYFTLLVLK..KLHES..KLNLDIILSNHSAEFIRDYANV-.....-.--QFT...GFY.NL.SI.GQGQSLARMQFLIGKG...LVKEEEVRSIVRDCYI........PKAKALSYTVS.P..EG..eLTLFSHAPIGLETIQGLAK.....................KF...D...LPYHD..KT.TKELIQTIDRINKKI.ETLFITHVTH------------...-----------------------....----------......--------------.......-.-------------gqf.........................................
A0A0Q9YWU8_9COXI/97-330              ...........LLRLIGDVVADRGANDYFTLKILK..KLRDN..GVPVVNMISNHDAEFIECYEKG-.....-.-KLFD...EN-.RL.G-.LQARSAGNLQKLIDQG...LIETQEVVELI-KAYK........PTLRALDYSLN.AakNK...ITIYSHGVIGLENINYIAE.....................ALgmnG...VHCDE.hSS.AIEIAQIIEEINIRF.AVQVKESTVSELLKLDSVDSRAi.nGVAPIDPQAFAFAHLVWNRDANS....-LKRPEH---......--INFVHGHDMKDK.......T.INNIFNLDNLLGK............................................
A0A222P2C2_9GAMM/173-413             ...........LIRFLGDEFADRGNCDYLTLRILD..FLTTN..DLKTTHLLSNHGCEFIYAYEKMV.....Q.SSVFE...NAG.FI.PD.FQTQSIQGLKLLLDNN...VISCEKLTTLINRSFK........PSLKILDYTLN.E..HG...ISLFTHAPVRFDSIELLAR.....................RL...D...VIYDG..ST.KEALGRTIDQINHQF.SSFVNSNNIHTLFSTAEIKDVA...HMTAEERVAWPAVYLTWNRWTAMk.diEETRPAGKNG......YSLTYVHGHDIFES.......K.LAYVHNLDTLCGK............................................
A0A378LXA9_9GAMM/174-414             ..........f-IRLLGDEIADRGHCDYFTLRMIC..LLAKN..HCPLNILISNHGSEFIYAFEELI.....S.GRSFS...PQG.YI.GD.HQIPSFWGLRLLLEHE...IISQEELIQLVDESYK........PALKIMDYSLT.E..NG...ITLFSHAPIRFDAIQLMAK.....................KL...G...VHYDD..AK.PEALAATIERINYQF.QYYIENNTIHSLFHNDAIHDRT...HMSEEEKMDWPLIYFFWNRWDEMk.etETARPARHHG......YGITYVHGHDEYHS.......P.LPHIYNLDTPCGK............................................
A0A0W0XML5_9GAMM/101-356             ...........LLRFLGDVVADRGNNDLYTLLIYE..WLLIA..KIRVETMMSNHDMAFISLVLNGE.....Y.SPHIAltvGYD.RL.PN.HQMRSTFGALFFLYHD...LFPEERFIHLF-SLYR........STLTLFACGKG.D..DN..eLILYTHAPVGLETLYAFYDeyklrmtdallatlplpketdNA...K...TCFYH..LG.AGELAKVIDAVNAVF.ASLDLRKAIDFERCYLEIFYRN...GLPHSMPIECPLFRLCWNRDTSS....-LQA---GTK......VKLTLIHGHDLASP.......-.-PWGKSLDNFLGK............................................
G9ELX3_9GAMM/244-487                 ...........LIRLIGDELADRGKNDYFMLAFMN..YLKKK..DVNFKITISNHSNEFITFNEGV-.....-.-----...QSD.VV.SS.YDRPSLAGLKLLLDNG...IVSKATMDGWVNNAYT........PNLKAIDYQLA.D..GNpptIRLFTHAPVRFDIIEKIAN.....................KL...G...VGYQE..GT.ANALAQTIDSINAAL.AEHIQAGTIHTLCTISPDIDPA...GLSPQEIEAHPLVYLIWNRWNPTvdqdETARPAEMKGffdvtrYNLEYYHGHDGAFS.......K.SPHVFNLDNGIGK............................................
A0A0Q9YLZ8_9COXI/95-330              ..........a-INLVGDVVCDRGENDYFTLKILK..KLHDS..HVPFEINYSNHDADFVTAYESQ-.....-.-EQFY...PG-.ML.-M.HFGVSMSNMQRLIEKG...LISREEVLEMTDSAYK........PHLKLIDYALS.D..NE...ISISTHAGVGLKNIRFVAN.....................KL...G...IAYDD..TS.ANALAETIDRINQKFsNDYVMTNRMGELIEQAMLAHGFygmNFDLEQQEKFPIEHMIWNRNYVG....-LDRPAEHNG......YKINFIHGHDSSEP.......S.HDNIINVDNMLGK............................................
A0A0W0VKN1_9GAMM/96-328              ..........s-IILIGDVLCDRGSNDYFTLKLLE..KLHES..GAHVETLLSNHDIEFIESYETN-.....-.EDRFQ...AKN.ID.HS.GQADSTNALQALIDKK...LISRDSVMLMVKSAYK........PTLKALAYTLN.D..DQn.eITIYSHAGIGLTNIQAIAK.....................KL...G...VTYWD..SS.VKSLAATIENINTKF.QEYVQNHTVHTLYDQDNIT---...-GEFQEPESAPFEHLMWNRSYST....-LDRPAQKNN......YQIQFAHGHDSTEL.......T.HEHIFNLDNVLGK............................................
A0A098G1U2_9GAMM/105-340             ..........t-LRCFGDMLADRGSNDLLSLLTLLemRLAFP..ELRGVILLSNHDKCLLSNYLRGA.....L.AP--G...KKL.TM.EL.SPCNSLTRLKWLIDNH...IISYDEVEDMIQKAYL........PALKLVDYVRK.E..DG..sIDIMSHAPLTLSAIDKAMH.....................EFl.pA...NHHKDiyAS.ADDVAYVLDQLNIIF.SEGLMDKKSPMYQ---------...ALTTPPSKTNPIYNFIWPRLTDI....--GPEIEVPS......YNCRFRHGHDGS--.......-.-------------pgeikihgvtyigynsifgk........................
A0A222P0C8_9GAMM/473-677             eeeiteqldnp------------------------..-----..-------------------QESV.....R.GSDFE...PSR.FF.GF.SVQKSMILLKWAIEED..kTVDWEEVVSLYNNIYR........PMSCVLSYTLD.H..ENn.gITLYSHAPIDVEVIQNLAK.....................AW...E...VKYDD..RT.PQALAASIDRINQHY.QQYAGSNQIHKLYDPQDMTAAA..sEYNLIDKQKNPFLFLMWNRDYTA....-INRSAQHNG......YFVSYVHGHDSGEL......iA.SANVRNLDNELGK............................................
A0A098GHV7_TATMI/89-326              ..........a-VTLIGDELADRGQNDYFTLLVLK..KLHDE..KANVNIMLSNHSVEFIRDYERE-.....-.--KFT...GQY.RL.LE.GQGRSLEGMQTLIKKG...LIDEKEVRDIVEQCYQ........PMVKAIDYTLT.P..EG..qLTIFSHAPIGLETVKALAE.....................KF...R...IPYRD..DS.IRNLIRTIDAINKVI.EKLSKEKQLAQLIELEGLANP-...--NYPIPLTKPLQRLIWNRALGN....ELMT-EPTGG......FKVKFVHGHVGPMSvlkngseA.LPTHENLDTLFGK............................................
A0A0W0YZY7_9GAMM/174-414             ...........LVRLIGDEFADRGSNDYFTLRLLG..FLHDN..KVEVHTLISNHGNEFVTGYENLI.....N.RHYLE...EVG.YV.HP.QQKPSFAGLRILLDEQ...VITESEVTSLINKAYK........PSLKILDYTLN.E..DG...ITLFTHAPVRFDSIQDIAS.....................QL...G...VDYDD..ST.KEALAKTIDKINQQF.AQIVEENRVHEYCTVDDPMDLA...DMSLEERKAYPLIYMIWNRWNENk.etEDARPASNND......YKIHYVHGHDPFQS.......P.MQHITNLDTPIGK............................................
A0A7J6YQY5_9COLE/94-330              ..........k-LRLLGDELADRGNNDYFTLKILE..KLKTA..GVPVEIILSNHSVEFIEVYEKQ-.....-.-EKFE...SQ-.ML.WD.GFAISMQRLQELVDKG...LVSREEILTIVDKAYK........PALRVISYSLN.RadNE...ITVFSHAAIGLNTIERLAK.....................EF...H...INYDD..IT.AKQLAQTIDEINKSF.RKKAKTNTIHTLYARKNMKDGF...SNPNTDLSDAPIEFIMWNRRYDV....-IDRPAKYNE......YSLCFVHGHDTPKIs.....nP.NAHIYNLDNQLGK............................................
A0A0Q9YIT3_9COXI/96-329              ...........LLRLIGDVTADRGTNDYFTLQLLK..KLRDK..GVSVVNLISNHDAEFIQPYETG-.....-.-KGFD...TS-.RL.G-.PQANSAANLQRLLDLN...LISKAELKELI-DAYK........PTLRALDYSLN.EakDK...ITIYSHGVIGLENINYIAE.....................ALemkD...VHCDE..NTpAIEMAIIIEEINARF.ADHVKNNTVTALLKLDKVDTDAi.nGKYPIDAKAFPFAHLVWNRKAHG....-LKRPEH---......--MNFAHGHDMNDK.......T.INNIFNLDNILGK............................................
A0A0W0VU49_9GAMM/106-346             ...........LVRLIGDEVADRGSCDYFTLRLIR..FLHEN..DVKVTILISNHNSEFIAAYEHLF.....I.TNELR...SLN.FI.IN.EQKYSFFGLKLLLDEE...VISETEVKELVQIAYK........PTLKILDYTLT.A..DS...IGIFSHAPTRFDVIKSLAD.....................YF...G...VVYEE..AN.KEALAGTIDNINHSF.KLAVKDNKVHEFFNIPWNIIVE...NLSAAEIAQWPLIYVTWNRWDAAk.etQDARPAELHD......YHIWYVHGHDNYKS.......Q.LPHVHNLDTYCGK............................................
A0A0W0YKU0_9GAMM/118-350             ..........k-IRFLGDDLCDRGMNDYYTLAIYK..RLDTA..AVPFEVVLSNHGNFFLTAYERPE.....Q.SFSYN...PYG.DGeNE.ALVQSMLHLGKIIDRG...LVDKKEVLDTVRNHYL........KHLVLPGYTLT.PakNE...ITLYSHAPVDIAMLASLAH.....................DL...K...VPFHD..DT.LDELRLSLDEINKQI.QQWIMSNTFSLNYWRLN-----...REHKKDNTQSPLKQVLWNRDYTI...lKRAYHPENKS......YTVNYVHGHDSM--.......-.-SNVFNLDNLFGK............................................
A0A0W0VDA6_9GAMM/93-336              ..........a-IRLIGDELADRGSNDYFTLRILQ..KLREQ..QVSVEILMSNHSVEFLQACEMHQ.....E.NKAFK...AP-.LL.KH.DHARSLENMQTLIERK...LITPKEVFEITDSAYK........PSLKVISYTLS.E..DDs.eIVIFSHAPIGLNTIADLAQ.....................QF...G...VNYED..ST.AVELAKTIDNINRKF.QDYARRNTIGKLCPAEAMYKGYs.dTFFSSDLKAYPFVGVMWNRGYVA....-IERPAEHNG......YKLVYAHGHDSHDPl.....qN.EAYVHNLDF----lntlgr......................................
A0A0W0W3D7_9GAMM/89-318              ..........h-LKLIGDELCDRGQNDYFTLVVLN..KLKQV..NMPVEIMLSNHSIEFLTNYQNN-.....-.--TLR...DPK.TT.IP.GYDNSIQGLSTLINNN...LISEQEITYLVESAYK........PCLRLLSHSHD.E..NN..nQTLYTHAPSALETVIALAK.....................KY...G...IKYRG..S-.QEHFAHCIDAINQYF.HDNFDQEIASLADKLNDEQLAF...GVGNPVSLEHPIVRLLWHRAGNI....ESIK-ELNLP......DWLSTVHGHEGDVR.......R.YLNLIN-------nqna........................................
A0A078KVF6_9GAMM/117-354             ...........LFRLIGDELVDRGMSDYFVLKLLQ..RLDKQ..GANFEIIPSNHGIEFVEACEKFA.....QnGNKLV...AAR.IK.NV.AHGNSFVALQESIEAG...AIKAEEILDIYNQSYK........KHLKLISYSLD.K..EGn.eIHIFSHAGIGLNHIRGLAE.....................KF...G...VPYSA..RN.AADLAKTIDNINKQF.ALKVDANEVHTLYSDEMMYRGY..tSKAKYNVKDEVIAAILWGRVYSD....-LERES--TD......FIVKFIHGHDDGDR.......D.-QTHLTLNEKLG-q...........................................
W0BDF9_9GAMM/93-330                  ..........s-LTLIGDELADRGNNDYFTLFVLK..KLHDV..NLDVDIMVSNHSAEFIRDYENP-.....-.--HFT...GAH.QL.FG.NQGQSLTNMQRLIARG...LVDEEDVRRIVDDCYK........PMVKAIGYTVS.P..EG..eLTLFSHAPIGLETIEALAA.....................KF...N...IPYHE..DS.PKALIKTIDAINDHL.RTLLGEKSLAQLIDAEGHSDP-...--RHPIPLTSPLMRLVWNRALGD....-ELRTESHGG......FKVHFVHGHIGDGAilqhgaiP.LPSHRNLDGWFGK............................................
A0A0W0YLA9_9GAMM/174-414             ...........LIRLIGDELADRGHCDYFTLRILD..LFSQN..HGRLAIIFSNHGYEFISAYEKLA.....K.NLPFV...PQK.DI.VD.FQTTSFSGLKLLIKHG...FITKNELVHLTNKSYK........PALKLIDYTLD.E..TG...ITLFSHAPMRFDHLELTAR.....................FL...K...VTYDD..ST.KEALAKTIDEINGQL.EHYIHEDITHLLFHSDCIKDKT...NMTEEERAMWPLIYLIWNRWDQAk.etETARPASNND......YLITYVHGHDPFQS.......P.KPHVHNLDTLCGK............................................
Q5ZTF6_LEGPH/118-350                 ..........k-IRFLGDDLCDRGMNDYYTLVIYK..KLDQA..NVPFEVILSNHGNFFLTAYERPE.....Q.SFNYN...PYG.EGeNE.STVQSMLNMGRLIDRG...LIDKQDILEMIQYHYL........KHIVLPSYTHN.K..DKn.eLTIYTHAPIDLGIISALAN.....................DL...Q...VPFKD..SN.LHELTKSLDAMNSKI.KQWILSNTFTRHYKELN-----...EAHNQINTPSPIKQILWNRDYSI...lDRHAHPNNKP......YGINYVHGHDSM--.......-.-PNVFDLDNLFGK............................................
A0A5E4PEX0_9COXI/92-253              ..........k-IHMIGDDLADRGQNDLFTLFIYE..KLNKE..KADFEVLHSNHGAQFLKQYDIGL.....D.NENMT...LYR.GA.HH.SFGLSLHNMQDLLDRE...LISLQEVTGLVDQHYL........PRLKLLSYIVE.N..DQ...LKILSHAPVDESRVKNLAA.....................LF...G...VTYTE..AS.AQDMAAMLDRINNIF.QIL-------------------...-----------------------....----------......--------------.......-.-------------cqgp........................................
#=GC seq_cons                        ............lRLlGD-luDRGpNDYFTLtlLc..+Lcps..plshcIllSNHuhEFlpsYEp.........tppap...s.t.hh.tt.spspShtsLphLI-ps...lIsccElhpllppuY+........PsLKllsYoLs.c..cs...ITlaSHAPlsLpsIptlAc.....................ch...s...VsYcD..so.sppLApTIDpINppF.pphlpssplppLhpttth.......thpt.p.tstPlhhlhWNR.hst.....htRstphps......YplpaVHGHDuhp..........hsplhNLDshhGK............................................
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