#=GF ID XopL_C
#=GF AC PF20817.1
#=GF DE Type III effector Xcv3220, C-terminal domain
#=GF AU Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE ECOD:3381.1.1
#=GF GA 27.00 27.00;
#=GF TC 102.50 273.20;
#=GF NC 22.90 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 --cpu 4 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 23359647
#=GF RT A pathogen type III effector with a novel E3 ubiquitin ligase
#=GF RT architecture.
#=GF RA Singer AU, Schulze S, Skarina T, Xu X, Cui H, Eschen-Lippold L,
#=GF RA Egler M, Srikumar T, Raught B, Lee J, Scheel D, Savchenko A,
#=GF RA Bonas U;
#=GF RL PLoS Pathog. 2013;9:e1003121.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found at the C-terminal end of the type III
#=GF CC effector Xcv3220 (XopL) from the plant pathogen Xanthomonas
#=GF CC campestris and similar proteins from Xanthomonadales. XopL
#=GF CC induces plant cell death, subverts plant immunity and shows E3
#=GF CC ubiquitin ligase activity, which is associated with this domain.
#=GF CC This domain interacts with plant E2 ubiquitin conjugating
#=GF CC enzymes and folds into a four-helix bundle, which can be
#=GF CC subdivided into two uneven lobes almost perpendicular to each
#=GF CC other giving the molecule an 'L' shape. A large cleft with a net
#=GF CC negative charge is formed at the intersection of the two lobes
#=GF CC [1].
#=GF SQ 2
#=GS Q5H205_XANOR/472-635 AC Q5H205.1
#=GS Q8P390_XANCP/340-492 AC Q8P390.1
Q5H205_XANOR/472-635 SVTTTELLHKAALERIEDAAHAMLSAVIDQERNPFLEGAPPYLPEKRPPGA-TTFGQIPVLKKMLRESRDRHFLKRVSEMAG-------PCP-RVEDQTEEGLSRHYMNVSNWKAQRSAHLGIVDHLRQFVYREGSQLDAATLAKAVQMWKTRELIVDAHPEDRARFPSFTIH
Q8P390_XANCP/340-492 SDDDPAITQ--ARQKIEDTVYALFAA-IDEDRNPFVQNAPYFIPEKREEGTPIVLGEVDGIQQMLKESSREVFKNKLIGLANSLQQRRIPHPWKASDRLDTAEHKAFVN---------SHLG--------TFNEHSPINGVSLYKAAQMWKTRELLVHNDPTNRDFLPPIPTY
#=GC seq_cons Ssssstlhp..Ahp+IEDssaAhhuA.IDp-RNPFlpsAP.alPEKR..Gs.hshGplsslppML+ESpcchFhp+l.thAs.......PpP.+spDph-pu.p+tahN.........uHLG........sapEtS.lsusoLhKAsQMWKTRELlVcscPpsRshhPshsha
//
