#=GF ID   ZirS_C
#=GF AC   PF16583.9
#=GF DE   Zinc-regulated secreted antivirulence protein C-terminal domain
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   pdb_2lv4
#=GF GA   26.00 26.00;
#=GF TC   26.20 87.50;
#=GF NC   25.60 25.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0159
#=GF RN   [1]
#=GF RM   22810234
#=GF RT   The zinc regulated antivirulence pathway of Salmonella is a
#=GF RT   multiprotein immunoglobulin adhesion system.
#=GF RA   Prehna G, Li Y, Stoynov N, Okon M, Vuckovic M, McIntosh LP,
#=GF RA   Foster LJ, Finlay BB, Strynadka NC;
#=GF RL   J Biol Chem. 2012;287:32324-32337.
#=GF DR   INTERPRO; IPR032262;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   ZirS_C is the C-terminal domain of ZirS, zinc-regulated secreted
#=GF CC   protein, that is part of a type V-like secretion system. The
#=GF CC   domain adopts a bacterial Ig-like fold. This domain interacts
#=GF CC   with its transporter ZirT, and ZirS also interacts directly with
#=GF CC   ZirU, the third component of this antivirulence complex.  ZirT
#=GF CC   is the zinc-regulated transporter through which ZirS is secreted
#=GF CC   [1].
#=GF SQ   5
#=GS A0A3S4GAZ4_SALBN/146-243  AC A0A3S4GAZ4.1
#=GS A0A2X4WDS2_SALER/129-273  AC A0A2X4WDS2.1
#=GS Q8ZP79_SALTY/132-275      AC Q8ZP79.1
#=GS A9MQ72_SALAR/56-200       AC A9MQ72.1
#=GS A0A509CAU3_9ENTR/1-119    AC A0A509CAU3.1
A0A3S4GAZ4_SALBN/146-243             ed--DVGSKIRIDHYNETDTASASGYSPVPSVSERHTLETKRIVK-LSPDLSAISTDKTSLMPGESAVVTIIIKDINNSPINI----------------------------------------------------------------kpyelkpahglvgnwgyy
A0A2X4WDS2_SALER/129-273             ..KEHSGSRIKLEVYNETDITSASGYMPVPSVSEPHYIETQPISNTPSPDLTLINIDNAVLSPGESATITTLVKDVDGNPINDVMIDVATAHENGNGLWDIGPVKKGVGPGEYTQVITYLGNHSETLGVEYSYLGDFFKKYLPITGR..................
Q8ZP79_SALTY/132-275                 ..KEHRGSKIKLEIYNETDMASASGYTPVPSVSEFQYIETETISNTPSPDLTVMSIDKSVLSPGESATITTIVKDIDGNPVNEVHINKTVARENLKGLWDYGPLKKENVPGKYTQVITYRGHSNERIDISFKYAMSF-TKEISIRGR..................
A9MQ72_SALAR/56-200                  ..KEHSGSRIKLEVYNETDITSASGYMPVPSVSEPHYIETQPISNTPSPDLTLINIDNAVLSPGESATITTLVKDVDGNPINDVMINVATAHQNGNGLWDIGPVKKGVGPGEYTQVITYLGNHSETLGVEYSYLGDFFKKYLPIIGR..................
A0A509CAU3_9ENTR/1-119               ..--------------------------MPSVSEPHYIETQPISNTPSPDLTVMNIDNAVLSPGESTTITTLVKDIDGNPINNALIESFIGYANGDGLWDIGLVKKGVAPGEYMQVITYLGHGSEMIQVNYRYQGNSFGKSLSITGK..................
#=GC seq_cons                        ..KEHsGS+IKLElYNETDhsSASGYhPVPSVSEPHYIETQPISNTPSPDLTlINIDNAVLSPGESATITTLVKDIDGNPIN-VhIssssA+pNGsGLWDIGPVKKGVuPGEYTQVITYLGppSEplsVpYpYhGsFFpK.LsIpGR..................
//