#=GF ID bpX1
#=GF AC PF19917.3
#=GF DE MoxR-vWA-beta-propeller ternary system domain bpX1
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF SE Aravind L
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.20;
#=GF NC 26.90 24.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 32101166
#=GF RT Highly regulated, diversifying NTP-dependent biological conflict
#=GF RT systems with implications for the emergence of multicellularity.
#=GF RA Kaur G, Burroughs AM, Iyer LM, Aravind L;
#=GF RL Elife. 2020; [Epub ahead of print]
#=GF DR INTERPRO; IPR045553;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC Uncharacterized domain found in the MoxR-vWA-beta-propeller
#=GF CC ternary system, a class of NTP-dependent biological conflict
#=GF CC systems.
#=GF SQ 57
#=GS A0A366H2Z9_9BACT/743-822 AC A0A366H2Z9.1
#=GS B4D8S6_9BACT/849-927 AC B4D8S6.1
#=GS A0A6B9ZCF0_9BACT/748-830 AC A0A6B9ZCF0.1
#=GS A0A5C1ANB3_9BACT/846-921 AC A0A5C1ANB3.1
#=GS A0A4V0HX14_9BACT/839-913 AC A0A4V0HX14.1
#=GS A0A2P8HKB3_CHINA/706-788 AC A0A2P8HKB3.1
#=GS A0A1A7KMK1_9FLAO/711-793 AC A0A1A7KMK1.1
#=GS A0A432MGV0_9BACT/879-957 AC A0A432MGV0.1
#=GS A0A086BL86_9FLAO/707-789 AC A0A086BL86.1
#=GS A0A5Q3LAH3_9BACT/834-914 AC A0A5Q3LAH3.1
#=GS A0A4R1ADU9_9FLAO/721-805 AC A0A4R1ADU9.1
#=GS A0A0C1KY40_9BACT/689-771 AC A0A0C1KY40.1
#=GS F4L0C9_HALH1/735-818 AC F4L0C9.1
#=GS A0A5K7XD07_9BACT/823-908 AC A0A5K7XD07.1
#=GS A0A1I3E1R9_9PLAN/823-903 AC A0A1I3E1R9.1
#=GS A0A517QKU1_9PLAN/824-904 AC A0A517QKU1.1
#=GS A0A2S1R1V0_9FLAO/714-796 AC A0A2S1R1V0.1
#=GS A0A316ECJ9_9BACT/708-795 AC A0A316ECJ9.1
#=GS A0A225DZD3_9BACT/888-968 AC A0A225DZD3.1
#=GS A0A3S2Y3U6_9SPHI/708-790 AC A0A3S2Y3U6.1
#=GS A0A653RPE8_9FLAO/772-853 AC A0A653RPE8.1
#=GS A0A2T6DNQ1_9BACT/948-1027 AC A0A2T6DNQ1.1
#=GS A0A848FNT5_9BACT/709-790 AC A0A848FNT5.1
#=GS A0A142WVY5_9PLAN/858-938 AC A0A142WVY5.1
#=GS M5THQ4_9BACT/854-935 AC M5THQ4.1
#=GS B9XN91_PEDPL/54-129 AC B9XN91.1
#=GS A0A0Q6AK56_9FLAO/708-790 AC A0A0Q6AK56.1
#=GS A0A6M5Z083_9BACT/625-700 AC A0A6M5Z083.1
#=GS A0A1I0R714_9BACT/516-596 AC A0A1I0R714.1
#=GS A0A7K1U487_9BACT/742-824 AC A0A7K1U487.1
#=GS A0A495J4Z6_9SPHI/705-787 AC A0A495J4Z6.1
#=GS A0A519LJQ8_9FLAO/114-196 AC A0A519LJQ8.1
#=GS G8TQB2_NIAKG/747-829 AC G8TQB2.1
#=GS A0A1K1RPS1_9BACT/689-771 AC A0A1K1RPS1.1
#=GS A0A0M9DSE5_9BACT/681-762 AC A0A0M9DSE5.1
#=GS A0A3G2G5J1_9FLAO/710-792 AC A0A3G2G5J1.1
#=GS A0A7G6YKX8_9BACT/727-809 AC A0A7G6YKX8.1
#=GS A0A2M9BPR8_9BACT/744-826 AC A0A2M9BPR8.1
#=GS L0DC97_SINAD/847-925 AC L0DC97.1
#=GS A0A255R7N9_9BACT/841-917 AC A0A255R7N9.1
#=GS A0A086F456_CHRP1/705-787 AC A0A086F456.1
#=GS A0A345H5F7_9FLAO/711-793 AC A0A345H5F7.1
#=GS A0A4Y8S4X5_9SPHI/705-787 AC A0A4Y8S4X5.1
#=GS A0A172TQY6_9BACT/689-771 AC A0A172TQY6.1
#=GS A0A3N7CEG6_9BACT/699-782 AC A0A3N7CEG6.1
#=GS A0A518AUG7_9BACT/855-934 AC A0A518AUG7.1
#=GS A0A1V9G630_9BACT/741-823 AC A0A1V9G630.1
#=GS A0A518DAC2_9BACT/831-915 AC A0A518DAC2.1
#=GS A0A518AXD1_9BACT/839-919 AC A0A518AXD1.1
#=GS A0A5B9QLA5_9BACT/848-925 AC A0A5B9QLA5.1
#=GS A0A6N4SRI6_CYTH3/678-753 AC A0A6N4SRI6.1
#=GS A0A142XHZ4_9BACT/863-941 AC A0A142XHZ4.1
#=GS I4ANR6_BERLS/787-869 AC I4ANR6.1
#=GS A0A518H2I3_9BACT/872-948 AC A0A518H2I3.1
#=GS H1YH71_9SPHI/701-783 AC H1YH71.1
#=GS A0A8J8GD96_9FLAO/703-785 AC A0A8J8GD96.1
#=GS A0A495IYR2_9SPHI/705-787 AC A0A495IYR2.1
A0A366H2Z9_9BACT/743-822 .........l-AQAEFEDGRRIVYDP.RGFLHVV...DGKSGV.ELSVM--VLKGTTTAWSSGTL----ERFGDGasgSLAALTSLSRLLLRALPA-----rlhsq...................
B4D8S6_9BACT/849-927 .........l-KMARWQDGRRAWIDS.CGLLHLR...CANPKL.PELTLCLGNERLAA-WTGTDLAWGDRFFIGD...--NFDAPAEEIWA-ILKAFA---apa.....................
A0A6B9ZCF0_9BACT/748-830 ........ll--RYNWPDGSELWFDKaRHMLYLR...SSDKAI.PEMAIPLVIQTQTACWASDGVICGNPYFRPK...-EVEVITVMDFHEKYFRPFIN--vi......................
A0A5C1ANB3_9BACT/846-921 ...rfppkfq----TQSGGWSAVFDR.LGQVVLL...DGAMPV.AAFLI---RRERAAACGHGGIRWGDPVLLGT...-----PPTPHAAQEFAKL-----fdr.....................
A0A4V0HX14_9BACT/839-913 ..fpvgegaa------AGPWRAVLDR.LGQVLLF...-ARGEL.VAAFV--VRRERAAAWLPGGVFWGTPALIGG...--PATPNA---------------ekligkaids..............
A0A2P8HKB3_CHINA/706-788 ..........LSRFTWADGSEAIADP.RGFLHLR...SSDKTL.PEITITMVLGITLAAWSSAGTYCGNSYFTED...GLALGLRAKEFYANYIQRFIA--gl......................
A0A1A7KMK1_9FLAO/711-793 .........k-NKFVFSEGSEIIADP.RGILTFK...SINKAI.PVFYLATTTDGFLA-IASDTEFGGSEFYLPE..sTLLKIKTVSHMYSEYLEPFIHQI........................
A0A432MGV0_9BACT/879-957 ...rrrfkat----CRGVGLVAVIDA.FGHVALA...DPSGTL.VCILL--ASRGRLAAWLPDGTRLGPAELTGA...-----PPSPGASARIAEALREA-s.......................
A0A086BL86_9FLAO/707-789 .........k-NKFTFSDGSEVITDV.RGMLTFI...SSNKNI.PVFYIPSSEYELLS-LATNTGFGGAEYYLPE..tTLLKMKKMEDMYSDCLEPFINQI........................
A0A5Q3LAH3_9BACT/834-914 .........l-QQARLPDGSTCMLDN.RGLLHIL...PADPKV.MEMTLTLPSSGPIAIRFEDGQANGPAYFVAS...--QTQTPAEQMYQTFMK------wvrktq..................
A0A4R1ADU9_9FLAO/721-805 ........kf-RYVTFKDGSEILFDN.KGFAHLK...STNENI.PEITIQLNLNSTPCFYVDGEAICAPTNMIHR..dFNVEILKPSEINERYLTPFINNI........................
A0A0C1KY40_9BACT/689-771 .........s-AFFVFNDGSSVTIYE.TGVITLV...SSHEGL.PAIHLPAVLDTSGA-MATATEFSGNEYYLAP..eNGQKKISVPDFYNRHIVAFIHHI........................
F4L0C9_HALH1/735-818 ........yt-RSVTWQNGSKITLDS.RGFLQLF...RPASPT.AEFTITLIIGQPLAAFSRSGAYTGNPYFYDV...SPDKITSPSHFYKTIIVEFIKKL........................
A0A5K7XD07_9BACT/823-908 .........l-SVARWPNGNACFLDS.RGLLHLV...PANRSL.PELTLVLHEGELTG-WRSDGQMWGKPYFIAG..sEKA--------------------gdersaatsrnlfeptirsfvhs.
A0A1I3E1R9_9PLAN/823-903 ........lh--AIHWKDGSQAVLDS.RGMLHLK...SSDAAI.PEFTLVLHEDCVAG-WSALGQVWGERYFHLD...-EKERTAPKVIWQDLIEPFVRR-l.......................
A0A517QKU1_9PLAN/824-904 ..........LKQATWNDGSLAILDS.RGMLHLR...SSDNSI.PELSLVLYDSNVSG-WCADGTCFGDEYFHID...-GCEKVPAETIYENVLKPFV---wtl.....................
A0A2S1R1V0_9FLAO/714-796 .........s-KRFVFPDGSAVYSDG.FGILTLK...SSNPDI.PAIYMPTTLHVPLA-MATDTCFVGSDDYYND..tKGTEYIAIDDFDAKYFQPFINTI........................
A0A316ECJ9_9BACT/708-795 .........k-DYFVFPNGYSVTVNR.LGILILSyfdSTNNRD.EKIFLPTVMDNQLG-VASYIHFSGNTFYSRRtdfEGRQTMKEQDFWDKYITPFIKDI........................
A0A225DZD3_9BACT/888-968 qsrfppgkga-----SAGRWTACVDR.LGQVLLF...GSAGAL.KATFI--VRRDKTAAWLPGGTFWGDPALIGG...-----PPTPDAAQTFARALTDA-g.......................
A0A3S2Y3U6_9SPHI/708-790 ........fi--KFIWADGSEAVLDS.RGLLHLK...SADTQV.PECTIILVLEKTAACWSADGKLTGNPYFIGA...SQAAVMLAADFYDRYIAPFIQRL........................
A0A653RPE8_9FLAO/772-853 .......eth---VVSKDGSTIKCN-.NGVLELE...SSNTHI.PKIYIPFIANYPSA-MATDEEFSGNPYFLPE..gSNLKTIPTEDFHEKYYNPFIQHI........................
A0A2T6DNQ1_9BACT/948-1027 .........l-SVATWEDGSKAWLDS.RGLIHLQ...PARTDL.VEITV--VLAERPGAWTSDGHLCGPVFFTGA...KLGAPAPAAPVWA-AIQAFSHE-l.......................
A0A848FNT5_9BACT/709-790 .....gsvry-----WKDGSKVVIDP.KGFIHLI...SSNPQL.AEVTITYVSGFNTACWSSDGRFSGNAYFFAE...-GTETVDPVWFYKNYIDPFIQHI........................
A0A142WVY5_9PLAN/858-938 .........l-SEARWPDGSTATLDS.RGLLHCR...SSDAGI.PEFTLVLSESRVSG-WCADGRRWGDEYFLGP...-NVQTVTDHDILQSLLRPFLRS-l.......................
M5THQ4_9BACT/854-935 .........l-RSAKISGGT-VWLDS.RGLVHFQ...-RDDDH.RELTLVLVDSHCAG-WFSDAGFFGPPFFSNTe.dNVIVDIPVPDSVLDWLESWAHQ-q.......................
B9XN91_PEDPL/54-129 .........l-RVASWNDGCKAWLDS.RAILHLR...GSSASF.PEVSIMLVEGQTAA-WSSDGQLCGSAFHLGA...--AESIEDSTMIRK---------iqsls...................
A0A0Q6AK56_9FLAO/708-790 ..........KNRFIFSDGSEIITDT.RGMLTFK...SSNNSI.PTFYIPSTVYGNLS-ISSNAEFGGSEYYLPE..sSLLKLKKIKEMYSEYLRAFID--ii......................
A0A6M5Z083_9BACT/625-700 ........ar--EAVRAPGWLAVVDR.LGQVLLY...GHSGAL.VAAFL--IRRERAAAWVPGGVFWGDPRLIGG...-----PATPGAGEKIGRAI----laat....................
A0A1I0R714_9BACT/516-596 ........ll--KFTWENGCEAFLDS.RGLLHLR...--APNL.PEVTIVLILNRSIACCASDGATCGTEYFTGK...SPEKKMPVQEFYEKYIQSFIEAL........................
A0A7K1U487_9BACT/742-824 .........l-VKFSWTDGSTAWIDNyRGLLHLR...SSDPSI.PEITIVLVLRMETSCRASDGAATGYPYFIRD...-AGQILKPNEFYSSYIQRFTQ--vl......................
A0A495J4Z6_9SPHI/705-787 .........f-TKFSWADGSEAVLDS.RGLLHLK...SADANI.AECSVILVVDQPTACWSADGKITGSPYFTGN...RQAGVMLAGDFYRDYIDSFIKRL........................
A0A519LJQ8_9FLAO/114-196 .........k-NKFTFSDGSEIITDS.RGMLTFK...SSNKNI.PVFYVPTSIGGFLA-MATHTEFSGSEYYLPE..tTLLKVRNSEEMYTEYLEKFIDQI........................
G8TQB2_NIAKG/747-829 .........f-SRFIWPEGSEVVADS.RGLLHLK...SADSSI.GEITIVMIVGKPTACWSSDGNVCGSPYFTGK...AGTEGAAVTAFYENYIQRFIDRI........................
A0A1K1RPS1_9BACT/689-771 .........i-TRYVLTNSVEAWMDS.RGLLHLR...SQDPNV.REITLVMIQNKPTACWAADGACCGYQYFTGE...KNAGLIPAHTFYESYIQPYIDHL........................
A0A0M9DSE5_9BACT/681-762 .........i-NFFRFGDGSKITINT.GGMLTFE...SSNPNI.PVFHCPSVLEQPLA-FASETFFIGNPYYKIN...HLQQKLITQQELASYLIGFIENI........................
A0A3G2G5J1_9FLAO/710-792 .........k-NKFTFSDGSEIVADS.RGMLTFR...SINANI.PEFYMPTSTHTGMA-LASETEFGGYEYFLPD..hTLLKVKTIAEMYENYLQPFIDQ-v.......................
A0A7G6YKX8_9BACT/727-809 .........f-RRVAWPNGSTALVDS.RGLLHLR...STDAAL.PEVTIVLVLGQATAAWASDGTVCGSMYFTGA...APTPSAPVGEFYHRYLRPLIEQL........................
A0A2M9BPR8_9BACT/744-826 ..........LQRFRWPGGSEAVVDS.RGLLHLR...SADASV.PEITLTLVLGQPLAFWAADGTVCGPTYFTGV...AREQSLSAPEFYEQYLRRFISS-l.......................
L0DC97_SINAD/847-925 ..skrflgsc----SFS-GLSVHVDF.IGQVSVL...GKTGEL.VCMFY--MFRNQLAGWMPDGTRIGPAHLTGG...-----PATENGEASFRTALQEA-s.......................
A0A255R7N9_9BACT/841-917 .........l-RTADFG-PNRILFDS.RGMLHLI...-KSSDQ.SEMTLVLNEECVSG-WTSWGEVFGEQYFTGL...---DTCPPSDRVFYWLNELTRQC........................
A0A086F456_CHRP1/705-787 .........k-NKFTFPDGSEIITDS.RGMLTFR...SSNKSI.EEFYIPSTAYGFLC-LSTSTEFGGSEYYLPE..hTLLKVKTMDEMYSRFLKAFIGQI........................
A0A345H5F7_9FLAO/711-793 .........n-QKAVFEDGSVIEIDK.NGIISFK...SSNPVI.PTFYLASYIGIGVA-LSTGEEFAGNDYFLPK..dAVVNKIQIHEFDIKYIEPFIQQI........................
A0A4Y8S4X5_9SPHI/705-787 .........f-TKYMWADGSEAVLDS.RGLLHLK...SSDTRV.AECTLLLVLEKTTAGWSADGKLTGNPYFTGN...RQTGVMLAADFYAAYIQPFIQRL........................
A0A172TQY6_9BACT/689-771 .........k-DTFAFPDGSTVIINR.GGMLVLK...SSDPSI.PKIYVPSVLDTALG-VSTTSDFAGNPYYLLL..dRSRRSISNPQFFQQYLEPYIKTI........................
A0A3N7CEG6_9BACT/699-782 .........k-DIFTFPDGSELLVDT.RGMLTLT...SSNTSI.PKIYIPAAQHMALGLVTSDGVFSGNDYFLRE..gQMNEPVNMAGFYTQYIQAFINTI........................
A0A518AUG7_9BACT/855-934 .......lri---ARLGVRFSVVLDS.RGLLHLM...PDSQQE.QEVTIVLAEGELTG-WRDDAVVFGRDYYLPE...G----------------------vegheprlasvrqvfkesie....
A0A1V9G630_9BACT/741-823 .........f-SKFVWNDGSEVLADS.RGLLHLR...SADKTI.PEITIVMVMGKPAACWAADGRVCGAIYFTGV...DTAESGDITGFYYNYIQRFIDRI........................
A0A518DAC2_9BACT/831-915 .........f-ATAVWGDSCRAELDR.RGLLHLI...HHDPSV.PEVSLVLAEGELTG-ACSNGQKFGREYFLRD..dE----------------------gylqraaqrrelceetvgrfveai
A0A518AXD1_9BACT/839-919 .........l-SMATFDDGSKLFLDA.RGLLHLY...SADRELvPEATLVLNEGMVSG-WCADGRVWGERYFIGD...--VDQTPPRDVYDSVVRAFCERI........................
A0A5B9QLA5_9BACT/848-925 .........l-RRADLPGGT-VWLDS.RGLLHMR...-SYRDD.SELTLVLHDDLLAG-WSSRWGSFGSPFFIGE...DSGKPVPPQ-VI-EWLRDF----nqdc....................
A0A6N4SRI6_CYTH3/678-753 .........p-NEFVFDDGSCIEVNR.SGVLILK...SSDENI.PLIYIPSIIESALG-LAAGNDFSGYEYYYKS...P----------------------lvelilkktgqnvlpq........
A0A142XHZ4_9BACT/863-941 .....rfpir--ESVFIGGWIAVVDR.LGQVLLF...RREGAL.VAAFV--VRRERVAVWVPGGVFWGDARLIGG...-----PTTPDAAEKIGRAISEA-g.......................
I4ANR6_BERLS/787-869 .........k-NEFIFEDGSSIFIDR.DGMIILK...SSNTEI.PTIYVPACLDCVLG-VGTDEYFAGVDYFLPL..dTNLEKIENQLFYVKFIQKFIQTI........................
A0A518H2I3_9BACT/872-948 ...rrfkatc-----RGPGLVAVVDD.FGQVALS...DSGGTL.LCIVL--ASRGRLAAWMPDGTRFGPAELTGS...-----PPTPGAGERIAAA-----lrga....................
H1YH71_9SPHI/701-783 .........f-TKFTWPNGSQMVLDS.RGLLHLK...SADSSL.TELSLLLVLDKPTACWAADGTVCGSPYFLGP...GATTVLPPGQFYQQYIQPFIDAL........................
A0A8J8GD96_9FLAO/703-785 .........g-NTFTFSEESNIVLDK.RGILIFE...SHNPEI.PKFYITSIVNGYLG-VASETEIAGNPYYYPK..eNTLEVIDNSEFIIKYFLPFIQNI........................
A0A495IYR2_9SPHI/705-787 .........f-TKFSWADGSEAVLDS.RGFLHLK...SSDADI.PESSIILVIEKTTACWSADGKITGSSYFTGN...RQSNVMLAADFYHTYIEPFIRQL........................
#=GC seq_cons .........h.pphsas-GSpshlDs.RGhLpLp...Susssl.schhlshshppssu.auucGphsGssYahss...t.hp.hsstphhppalpsFlpt.........................
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