#=GF ID bpX4
#=GF AC PF19920.3
#=GF DE MoxR-vWA-beta-propeller ternary system domain bpX4
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF SE Aravind L
#=GF GA 27.00 27.00;
#=GF TC 41.30 30.40;
#=GF NC 22.90 22.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 32101166
#=GF RT Highly regulated, diversifying NTP-dependent biological conflict
#=GF RT systems with implications for the emergence of multicellularity.
#=GF RA Kaur G, Burroughs AM, Iyer LM, Aravind L;
#=GF RL Elife. 2020; [Epub ahead of print]
#=GF DR INTERPRO; IPR045549;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Uncharacterized domain found in the MoxR-vWA-beta-propeller
#=GF CC ternary system, a class of NTP-dependent biological conflict
#=GF CC systems.
#=GF SQ 71
#=GS A0A225E8D2_9BACT/1-166 AC A0A225E8D2.1
#=GS A0A0Q6AKJ1_9FLAO/6-207 AC A0A0Q6AKJ1.1
#=GS A0A3G2G5Z0_9FLAO/6-207 AC A0A3G2G5Z0.1
#=GS B9XN87_PEDPL/2-199 AC B9XN87.1
#=GS A0A3N7A430_9BACT/5-207 AC A0A3N7A430.1
#=GS A0A6C2YID1_9BACT/3-202 AC A0A6C2YID1.1
#=GS A0A7G6YKX5_9BACT/2-202 AC A0A7G6YKX5.1
#=GS A0A5B9R0R8_9BACT/5-208 AC A0A5B9R0R8.1
#=GS A0A5C1AL10_9BACT/3-197 AC A0A5C1AL10.1
#=GS A0A1V9G5N2_9BACT/1-185 AC A0A1V9G5N2.1
#=GS A0A519L972_9FLAO/1-131 AC A0A519L972.1
#=GS A0A437MYZ3_9SPHI/2-202 AC A0A437MYZ3.1
#=GS A0A432MGE9_9BACT/5-208 AC A0A432MGE9.1
#=GS L0DCU0_SINAD/2-167 AC L0DCU0.1
#=GS A0A517QKN6_9PLAN/2-196 AC A0A517QKN6.1
#=GS A0A366H4S1_9BACT/9-211 AC A0A366H4S1.1
#=GS A0A1K1RQC9_9BACT/2-202 AC A0A1K1RQC9.1
#=GS A0A7K1U4A1_9BACT/2-203 AC A0A7K1U4A1.1
#=GS A0A2P8HKB4_CHINA/2-202 AC A0A2P8HKB4.1
#=GS A0A172TRK5_9BACT/4-205 AC A0A172TRK5.1
#=GS H1YH68_9SPHI/14-214 AC H1YH68.1
#=GS A0A4Y8S413_9SPHI/4-209 AC A0A4Y8S413.1
#=GS A0A2S1R1R6_9FLAO/7-208 AC A0A2S1R1R6.1
#=GS A0A142WWV2_9PLAN/1-206 AC A0A142WWV2.1
#=GS A0A4Q2XZU2_9BACT/1-74 AC A0A4Q2XZU2.1
#=GS A0A086BL89_9FLAO/6-207 AC A0A086BL89.1
#=GS M5TIJ3_9BACT/4-201 AC M5TIJ3.1
#=GS A0A1M7CUU4_9BACT/2-202 AC A0A1M7CUU4.1
#=GS A0A327RAE5_9BACT/2-196 AC A0A327RAE5.1
#=GS A0A518H2J0_9BACT/3-194 AC A0A518H2J0.1
#=GS A0A4V0HT92_9BACT/3-180 AC A0A4V0HT92.1
#=GS F4L0D2_HALH1/3-203 AC F4L0D2.1
#=GS A0A653RJ85_9FLAO/7-208 AC A0A653RJ85.1
#=GS A0A173MK28_9BACT/7-208 AC A0A173MK28.1
#=GS A0A518AUF8_9BACT/2-201 AC A0A518AUF8.1
#=GS A0A5Q3L9V8_9BACT/180-232 AC A0A5Q3L9V8.1
#=GS A0A255R6V0_9BACT/6-207 AC A0A255R6V0.1
#=GS A0A086F453_CHRP1/6-207 AC A0A086F453.1
#=GS A0A518AXE5_9BACT/2-201 AC A0A518AXE5.1
#=GS A0A0D6TJX7_9FLAO/1-187 AC A0A0D6TJX7.1
#=GS A0A433WC43_9BACT/2-202 AC A0A433WC43.1
#=GS A0A848FLL3_9BACT/2-201 AC A0A848FLL3.1
#=GS A0A4Q2XZJ5_9BACT/26-231 AC A0A4Q2XZJ5.1
#=GS A0A5K7XHC4_9BACT/2-201 AC A0A5K7XHC4.1
#=GS A0A495IYP9_9SPHI/2-201 AC A0A495IYP9.1
#=GS A0A8J2XRH8_9BACT/8-210 AC A0A8J2XRH8.1
#=GS I4ANR1_BERLS/4-222 AC I4ANR1.1
#=GS A0A0C1IEN2_9BACT/8-207 AC A0A0C1IEN2.1
#=GS A0A0M9DT48_9BACT/1-199 AC A0A0M9DT48.1
#=GS A0A1A7KFT6_9FLAO/6-207 AC A0A1A7KFT6.1
#=GS A0A2T6DBS2_9BACT/2-213 AC A0A2T6DBS2.1
#=GS A0A142XHS1_9BACT/3-200 AC A0A142XHS1.1
#=GS A0A316ECF5_9BACT/4-205 AC A0A316ECF5.1
#=GS A0A6N4SRM9_CYTH3/5-207 AC A0A6N4SRM9.1
#=GS G8TQB5_NIAKG/1-185 AC G8TQB5.1
#=GS A0A7R9LJ36_9ACAR/828-1029 AC A0A7R9LJ36.1
#=GS A0A495J5L9_9SPHI/2-202 AC A0A495J5L9.1
#=GS A0A1T4TKU9_9BACT/2-202 AC A0A1T4TKU9.1
#=GS A0A345H5G0_9FLAO/21-224 AC A0A345H5G0.1
#=GS B4D8S9_9BACT/2-197 AC B4D8S9.1
#=GS A0A2M9BPV6_9BACT/2-202 AC A0A2M9BPV6.1
#=GS A0A1I3E1J3_9PLAN/6-204 AC A0A1I3E1J3.1
#=GS A0A518DAE6_9BACT/1-200 AC A0A518DAE6.1
#=GS A0A6M5YXZ0_9BACT/3-198 AC A0A6M5YXZ0.1
#=GS A0A5Q3L9V8_9BACT/1-169 AC A0A5Q3L9V8.1
#=GS A0A0C1G0U7_9FLAO/7-208 AC A0A0C1G0U7.1
#=GS A0A6B9ZGS1_9BACT/2-202 AC A0A6B9ZGS1.1
#=GS A0A8J8KCH6_9FLAO/7-208 AC A0A8J8KCH6.1
#=GS A0A5B9W5U5_9BACT/134-332 AC A0A5B9W5U5.1
#=GS A0A4R1ADS2_9FLAO/1-200 AC A0A4R1ADS2.1
#=GS A0A1I0R791_9BACT/2-202 AC A0A1I0R791.1
A0A225E8D2_9BACT/1-166 ........-------------------..--..--.----------.....-MLRAAFEQQALDV..A.GPVIAFDPESALEAAVKLARACWWMVTFEDKTGV---.PLA...SGSE.......PQSPAD....HLSADVCFRFLPAVYRRARSRDPGHPLTLELTSLLRRWPLSDVLA.........DLDDGPT...TPLEFGGHPGLQQLYAERLARTGRPTWV.P.AT.GPArEWVDRVFHELGKPV----pvsl..........
A0A0Q6AKJ1_9FLAO/6-207 .......p-FLDTLFLLRKDECITIFS..DL..KE.ISKGEEKDAA.....DYFESEFEKERLEF..L.SDQIICDKETAVWAAKVMYHSVQLYLIRENTAKNLST.LIP...DFKG.......ERNVSS....LLSADLSLRFLPQIIMALQSVDPEDSLIKMLEQILTQFHYSGIGF.........DLNLDTI...NWEEELKDKTYRKLYLERIVEKKAYKLA.E.IP.YIN.HLLMAEFRMYKDHFWREL..............
A0A3G2G5Z0_9FLAO/6-207 .......p-FLDTLFLLRKEECITIFE..EV..KK.ISPKEEQEAA.....AYFETEFEKEGLEF..L.SDQIAFDRDSAVWAAKILYHSVQLYLVRENTEKDLAR.LIS...PFKG.......KFTLSS....KLSADLSLRFLPQIIIALKNLDADDPLIPLLETILQQFHYSGIEA.........DLDLEKL...NWEQELQDKTYRKLYLERIVENKVYRLA.E.IP.YIN.ALLTAEFGWYKNVFWKEL..............
B9XN87_PEDPL/2-199 .......g-LFQFLNALAESGSVIVT-..--..QD.FREEVEPEAE.....EVLKEMDRLYRSHL..P.GKAPDFVPEAALWGAKMLYRGCQFLVCRDIDGDIVSK.AMQ..eACPL.......PHSPAT....DYSVDLTFRFLPDLIGMTRGVSSGDPLLQALLKIATEWPLSSVGV.........TGVEGV-...NVSHFISDRCLRQLYIDRILERNDLTRL.G.SL.EVN.QAIKESLGAHVELCP---tv............
A0A3N7A430_9BACT/5-207 ........YFLDTLMQLRNSEELVLFH..KS..FT.IDAEEAALVT.....DFLERCYDEECLSY..P.GQAPPFNAAAALWAAQTVYFTAQLYLFRTDTLKDLAG.LFP...EPKF.......SADAGA....ILSADLCLRFLPKLIQELRYADPEDPLCALLARRLVPFHYSAIGT........kEVAIDSI...NWEQEPTDSCYRYLYLNRIVERKDLERA.A.VP.YWK.QSISDHLGAYKTTFWKAL..............
A0A6C2YID1_9BACT/3-202 .......t-FAEFLHSLLIWGEVALLE..RP..-I.LTDAGRAESL.....QLLRQVGERHLDSL..P.GPRLELACETALSVAEWFADLCWWIVASESPQSQ--A.WNR...GVPV.......PHTPAE....HFAGDWILRFCGMPERRLRFRPIDDPVRTGLDAMLRAWPFSGVRF.........PIDAPPT...TPLDFGGHLGMQWQYAQRLRDQPRPGWL.PtDP.DFR.ERIELAFAQVNR------pmpgal........
A0A7G6YKX5_9BACT/2-202 .......l-LTPFLRDLVSTGAVTLTS..QP..SA.FEADDLHAAD.....TLLADYHAEDALEL..P.GTVPAFAAPAARWAAQYVYHTLQLALVRELDEDVMQQ.YLP...AYTG.......DVTPET....IYSVDLTFRYLPDLLRLAKGLAPGDALVAQLQDIARQWPFSFVGH.........PEVDAT-...AEAAVLSHPALQLAYVDRIIRQQDQQRA.R.QP.HLL.PLVRAALGGHAATLWPDF..............
A0A5B9R0R8_9BACT/5-208 .......p-LAEFAQRLLHDGHAAVPAlpAI..LE.PAAEDQQQAT.....AILCEAERVLRAAA..P.DTPPALNAAAALWALRVFAWAGYTALDRNQERTTLPD.ELS...PSQP......dATHLDS....HWSVDVVFRFLPELCRRAERIAPEDKLHATLQTLAAQWPMSSVGM.........PIDWSVE...SLQMVMADDSLCRILVDRVTARADKRMA.A.DE.TVQ.KTLRDDAGAYAEQL----klq...........
A0A5C1AL10_9BACT/3-197 .......s-FVDWLRRVVLMGESVQDA..P-..PV.LTESDRAAAL.....PILRASFDRHLLEV..A.GPPLVFDAATAVWAAEALAAACWELVAGDVGESAAGR.E--...----.......PRTPGE....HLTADVLLRFLPPVYRRAKARDAAGPLARRLETMLRRWPLSGVLL.........DLDGSPT...TPSDFAGHPGLQLLYAERLVANPRSGWL.P.PA.GPGrDWAERIFEERGRPLP---re............
A0A1V9G5N2_9BACT/1-185 ......mg------------------G..QV..IP.FSAEDIEAAT.....QCLHQQYNYQAQEL..T.GPIPAFHAGAAIWAAGFLYRAVQLTMLRDLGEDVVNG.LLL...PFNG.......PVSPET....ILSVDISFRNLPNLLGLAKGLAPEDVLVKRLQAAATEWPFSSVGM.........KVEGIM-...NMDAIMNNACLRRAYIDRIIEARDSRRC.N.NV.QVN.EYIKEALGDHGQLLWPG-w.............
A0A519L972_9FLAO/1-131 ........-------------------..--..--.----------.....--------------..-.-----------------------LYLIRENTAKDLDK.LIP...KFKG.......TQNISS....ILSADLSLRFLPQTILALQNADPEDPLVKMLENILTQFHYSGIGY.........DLDLGKI...NWEEELKDKTYRKLYLERIVEKKAYSLA.E.IP.YIN.QLLIAEFGIYKDVFWREL..............
A0A437MYZ3_9SPHI/2-202 ........KLSKFVQGLFTEGVVNVPR..QL..LE.FHADDLRETA.....ILLQQYQLAERLEL..A.FNAPDFDESAGLWAAQYFYRAIQFVLLRELEEAAIQA.YLK...AYEE.......PVTCEA....IYSVDLIFRHLAPLFKLSSGLAPSDPLVQMLKETAAAWPYSSVGL.........DITPSV-...STAVIINHPSLKYAYIDRIIQHRDQKRI.T.NN.MEK.QALEEVLGLYSDLLWPKL..............
A0A432MGE9_9BACT/5-208 .......t-LAEFLERLLGEGRVAFRG..PP.mAS.ATGDDRAAAV.....VILRTAFAEDLMEL..A.GPPLPFDEKTAIAAAEWTRRACWFLISRGEPTEVVDR.ALG...GFPM.......PRDASA....HLAADLTFRYLPALRRRARAIDPDDVLSRRLDEVLRRWPLSGVLA.........DLDASPE...SPTDFDGHEGLLLRFSERLIDHERRSWA.P.GS.PLGrEILALALEAAGR------prsall........
L0DCU0_SINAD/2-167 .....das-------------------..--..--.-----SPAAK.....QLLQVAFDAYRLDI..A.GPPIEFDAGTAIEASSLVIRASWALVNHDSSSAEIKR.WVA...MSHR.......PTTPSH....HLTADLLFRFLPQLRKRALAKHEPDPLAERLATLLRHWPLSGVLA.........DLDTGPD...SPPDLCGHSGLMQLYAERWAKYQNPNWR.P.DE.SLN.EYV---------------dlvr..........
A0A517QKN6_9PLAN/2-196 .......t-VANVIRQLFEDGRLVLQT..DQ..RP.TLG-EICKGV.....DVVVEFEPVFRQTL..A.LTPPDIAQDAVSWSVEQFYLIAQRVAYQHLDQNRIEF.HFD...----.......APPADA....LYSVDLLFRFLPDLLRLSQSTDVNASLTERLMNLATDWPLSSVGI.........ALSAEP-...EVQAILDCRSLRILYVDRIIAAGDVDRL.S.HS.EIR.NDVRAAIGANPQLS----pkl...........
A0A366H4S1_9BACT/9-211 .......p-LAEFASGLFSTGKVVVRR..K-..VD.LTPDD-PQAV.....MLLHEAYQVAIDEWidD.SAAPEFQPGMALEALRCLYRLCHALVDRALSADEVEA.IFS..lTPTA.......PANAAE....MLSADVVLRHLPALQQWAKSLSSEDPLLVGMPAFGMRFPLSSVGM.........GELPLPV...DLTILKGHQGLWQLYIDRVIERQDASRL.T.DP.EVK.AAVRDALGSHSTLAP---rla...........
A0A1K1RQC9_9BACT/2-202 .......e-LTEFISGLINEGNVTVAA..DL..LS.FEEADLRTAA.....IHLQQYYEDDCREM..P.YTAPALDMEAARWAAGYLYTTVQFILLRNLDASLLET.HLP...AYKG.......ERTAAA....IYSADLTLRYLPDLFLLAKGLSPEDPLIARFYQTAHQWPFSAAAI.........PLTEQV-...DLSAINEHPSLRQAYTDRIIQARNLSQC.R.LP.ENL.PFVQAALGTHAAILWPQF..............
A0A7K1U4A1_9BACT/2-203 ........KLTDFISGLINDGSVTVAP..KI..IP.FSADDLKQAT.....MHLQQYQEDDTADM..P.YSAPEPDLAAALWAAEYLYRTVQFILIRNLDENALHN.CIQ...PYTG.......NMTPAA....AYSADLTLRYLPDLLNLAKGLSPDDPLVKQMRATAATWPLSAAAI.........NDMPAGE...NLSVILSHPSLRQAYVDRIIYAGNKEKC.S.HP.DCL.PLVREALGAHTATLWPQF..............
A0A2P8HKB4_CHINA/2-202 .......n-LSAFITHLVREGQVTVAS..NI..HL.FSPQELQNTI.....VVLQEYYDNDIQDM..P.GTAPAFDSNAALWAARYIYRAVQLAMLRQLGEEEITT.LLL...PYDQ.......PVTAAT....IYGADLCLRYLPDLLSLSKGLSPEDPLVKHLQETAKQWPFSSTGI.........NIPATQ-...GIDIIVSNPSLLQTYVDRIIATRDTGRC.N.VQ.PVL.AAVKASLGNYAEVLWPDF..............
A0A172TRK5_9BACT/4-205 .......d-ILQTIEHLRHYEEIMLYG..NL..LD.VAENHEREVA.....DYLEKEYQLERLHY..P.FDAPVFEPAAAQWAGKYIYIAAQLLLYRENKPDELAA.LLA...PYKG.......VITAGA....ILSADLVLRFLPDIIKHLKAIDPEDNLVDLLEEQLHIWHYSAIGY.........SLRQDAL...HFENIVSNPCVCQLYTDRVVVHKDHRLA.A.HP.ALR.KHVLASLGLHVPTYWNDF..............
H1YH68_9SPHI/14-214 ........KLSEFLNDLFSRGEVILPR..EM..AR.FEGDDLAKST.....GLMMQFYEADRLEM..P.FPAPGFDAAAALWAAQYLYHATQLMMLRNLGASVIDE.YLQ...PFSG.......PANADA....IYSADLILRHLPSLLRLGSGIAPGDELVKRLRQTAAQWPYSSVGL.........NIEPEV-...DTAIIMAHPSLKYTYLDRIIQHADTGRL.K.GA.TER.AALDEILGMHQPLLWPG-l.............
A0A4Y8S413_9SPHI/4-209 ........KLSEFLNRLFTEGVVTVPR..QL..LA.VEEADLREAV.....RLIRQFYESDRLEM..A.YVAPVLDEAAALWAAQYFFRAVQFVLLRDLEEDQMAI.HLQ...PYGR.......EVDAGA....VYAVDLVFRYLGPLFKLSSGLAPDDPLVERLRATAAAWPFSSVGL.........GVDVSTDdlvSLDVIFSHLSLKYAYVDRVILLRDAGRT.N.DNvKVA.AALQEVLGLHQKILWPSL..............
A0A2S1R1R6_9FLAO/7-208 ........PFLETLYHLRTVEHIILYN..RL..AP.IPYREEQDVI.....AFLEGEYEREATDY..P.FTAPPFSPNAALWAAKTVYGAAQLFLYREDKATELKS.LLP...PYSG.......GIDASA....MLSADLCLRFLPSIKHALEKVDVNDPLITILNAYLKDFHYSAIGT.........DEGPSAA...NLAAAMDNDCLRQLYLDRITERKAAKWA.D.EA.TIK.SALLANMGDYKNDFWREF..............
A0A142WWV2_9PLAN/1-206 ......mv--RSYFESVFLTGRGGIGP..A-..DA.PSRKEIQEAV.....AWIAVFEQDYRLHL..A.GTPPALHLPALTWAVGQFYRASQCFAHRHLGEEVVSR.DLAenaPMPS.......GGPPATlvpiLYSVDLVFRFLPDLYRLAKAASEGDPLGQVLLRWGRAWPLSSVGM.........PLDSIG-...SIEPIVHDPCLRSLYVDRIVSAGDRSRL.V.DA.RIR.EAIRIAGGAHPELV----shl...........
A0A4Q2XZU2_9BACT/1-74 .......m-------------------..--..--.----------.....--------------..-.-------------------------------------.---...----.......------....-------------------------------------FPLSGVNIqpe...rppTEEMPPA...TWGNLQSHSGLRQLFLDRILTTRAGHWL.D.HS.ETS.LAIRHSLGEHYQTLVPA-f.............
A0A086BL89_9FLAO/6-207 .......s-FLDTLFLLRKEECITIFS..DR..YT.VSKKEEADAV.....DYFESEFEKERLEF..L.SQSINYHKDAAIWSAKILYHAAQLYLVRENTAKDLSQ.LFP...QFSW.......IRNVSS....ILSADLTLRFLPQIITALRDLDSEDPLIGLLENILSEFHYSGIGY.........DLNLEKT...DWEKELEDKTYQKLYLERIVEKRAYQLA.E.IP.YIN.QLLIAEFGIYKNEFWREL..............
M5TIJ3_9BACT/4-201 pisdvfda---------INQGSVVVVG..TSdtHA.ISPTDEDRLR.....TLIRETDRLARSDA..P.GDAPPLCLRSACWAAQTMHFLCRTLLDRIDVATELPA.DLA..aNRPS.......GTSASE....HWSVDLVLRVLADIDRRCAGANQLDPLRTTIRELAARWPLSAIGI.........QTDLSPK...SMSVVLSHPTLRRILVDRIVARGDADRA.N.LP.CVA.DEIAAA------------tptkip........
A0A1M7CUU4_9BACT/2-202 .......n-LAIFITTLIQDGKVSVDT..DI..SP.FSADVLQETV.....TILQSFYHNDVPDM..P.GTAPAFHADAAIWGATYIYRTAQLFTISSPEDEDITR.LLV...PFSG.......AINAAT....IYSADLSLRYLPDLAGLNKSHATNSKLLEQLQETAAQWPFSSTGM.........KILAAQ-...VPDSLLQHPSLLAAYADRIIVTRDHGRL.R.HP.KVL.QAVVKALDNYQEILWPGF..............
A0A327RAE5_9BACT/2-196 .......k-LLAFTQTLLGSGRAIVAS..HI..QT.YSMDDEHATV.....EYLSKHYDRLKLAL..P.GNPPIFDRGAALWATKIMYRAAQCALIQHWSKEEINA.LLP...DYNN.......SIHPSS....IVSADLVLRHLPKVMHAMQDLPAKDRLL----AIAHAWPLSSVGI.........ELPKPI-...DATLILEHDTLRGMYIDRIIATQNVTLL.Q.-P.SKK.PWISAMIADEST------lppkm.........
A0A518H2J0_9BACT/3-194 .......t-LAEFLERLFGEGRVSFTG..PP.pPS.PAEAERSEAL.....GPLRRAFADDLMDL..A.GPPLPIDGPAALAAAEWTRLACWFLVSRGAPPEVVDR.ALA...PPPP.......PRSAAA....HLSADLTFRYLPGVHRRARAIDPGDVLASRLAEVLRRWPLSGALS.........DVQGVPT...SPVDFFGHDGLMLRFAERLALREAPDWI.P.T-.---.------------------rgrglelwdlt...
A0A4V0HT92_9BACT/3-180 .......t-FRDWLERTLSRGESVLDA..P-..PA.LLPADHADVD.....DLLRAAFATHALDV..A.GPSLEFDATTAREAALALARACWFLVRPPEDTSPVKL.LLT...---A.......SPTPAA....HLSADVSLRLLPAVHRRASRREPGGDLARQIEALLRQWPLSGVLA.........DLEGAPT...TAPEFGGHAGLQLLYAERLAAT------.-.--.---.------------------ggrvgwvpvs....
F4L0D2_HALH1/3-203 .......s-LNQFLSDLWENGKVEVAH..EV..QP.FSPTELLEAQ.....RNLHTFYRQDCLHF..P.GTAPEFDATAALWSAQYLYRATQFILLRHLNEQAMQE.QLM...PWMG.......QTSPAV....TYSADLCLRHLPTLLNFAKGLSPADVLVLNLKKTATDWPFSGVGI.........AEENVQ-...AEELILSHPTLALAYVDRIIAKRLQAKA.Q.QA.AIL.PWVAAALGDHANLLWPEW..............
A0A653RJ85_9FLAO/7-208 ........PFLDTIYHLRTREHAIIYD..KK..LD.ISKEEEQEVI.....ELLRDEYEKEKLNY..P.FQAPDFDESAALWGSKIVYFATQLVLNREDTASKISA.LFP...DFGK.......AITPSA....MLSADLCLRFLPLLLLQLQHMDADDMILPVLEQKLKQFSYSGIGY.........DMDLENL...DHSVVLSDDCMTQLFLDRVVEKKDKNRG.N.LE.VIK.PLLLANFGDFKTIFWNEL..............
A0A173MK28_9BACT/7-208 .......f-FLDTIYHLRNHEEILLHT..SY..TP.PLEEDKELLT.....HFLEMEYGNECLEY..P.GTAPVFDGAAALWGAQVVYTASLLLLDRKHHVEEIPT.LLP...SYTG.......PVTEGA....MLSADLCLRFLPQIIKQLQAIDAEDVLIPLLEQVLTRWHYSGIGL.........ELGIENE...LLEIALRHNCLRQLYVNRIIQYQYKPLA.T.HP.LWQ.PWVMAAMGNYTTYFWKDL..............
A0A518AUF8_9BACT/2-201 ......sa---EFVHHLLE-GRPLFVG..AP..TP.WDEQTKREAS.....VVLVRFEEDYRICL..P.QDPPELDLDAALWAAESFHHAASLLVNRDYGDDVIVQ.TLD..tPASD.......RTQPET....HYAVDLTMRFLPELLKLAKTAAPEDTLVGRLMAWAAAWPLSSVGV.........AGVGPV-...DAAVLRTPPMLLRLYVDRVIAASDGSRL.D.DE.VVA.ESVKSALGNYPELSP---rla...........
A0A5Q3L9V8_9BACT/180-232 kipslplk-------------------..--..--.----------.....--------------..-.-------------------------------------.---...----.......------....---------------------------------------------.........-------...TLEPIWQHRSLRQIYIDRVVLSKDQSRL.R.DP.RVK.VAVEALGG----------gvp...........
A0A255R6V0_9BACT/6-207 .......a-LTKFVIDLLGEGRVKTRG..RIhlHQ.ASQADRESAS.....MVLVGSAVIAADEV..P.GVAPAFVLPAALWAAEAFAWACGMLIDRAEVETNIPP.WII..kSRPA.......TNDLSS....HWSVDLVFRFAYDLIKRSESISPNDDLHAQLLELFTPWPVSAVGL.........HHEPPQA...ESNLVLTHSTLRQMLVDRTLLRQDKHWL.Q.DS.RIK.HDIEVVLGGYPELF----t.............
A0A086F453_CHRP1/6-207 .......p-FLDTIFLLRKNECITLFS..SL..QE.ISEKEEMEAE.....EYFEAEFEKERLEF..L.SDRITCDPKTAVWAAKIVYHSAQLYLIRDNTEKNLEK.LIP...EFKG.......TRGVTS....IISADLSLRFLPQIILALNAIDPEDSLIKMLEDILTVFHYSGVGY.........DLDLKYV...NWEKELEDKTYRKLYLERIVEKKDYKLA.E.IP.FIN.KLLIAEFGMHKEAFWREL..............
A0A518AXE5_9BACT/2-201 .....dyv---QFWKDLFEEGRLALPA..F-..AA.LTERELSQGA.....SVLVAYEGRLRREL..P.SGLPKLEVEAVSWAGRNFYRASQFVVYRDVGAETINEeLFP...SWSG.......RVDASV....HYSVDVVFRYLPDLVRFAGSAAPGDPLLEHLGRWARDWPLSSVGM.........EGIVGV-...DIAAIAGHRALMSIYIDRIIATRDTSRL.A.DK.RVR.EAVDAALGMYPELA----agl...........
A0A0D6TJX7_9FLAO/1-187 .......m----------------IYD..KK..LD.ISKEEEKEVI.....ELLRDEYEKEKLNY..P.FQDPDFDEVAALWGSKIVYFTTQLVLNREDTASKIST.LFP...DFGK.......PMTPSA....MLSADLCLRFLPQLLLQLQHMDADDVILPVLEQKLKQFPYSGIGY.........EMNLENI...DLSIVLSDSCLTQLFLDRVTEKKDKNRG.S.LE.VIK.PLLLANFGDYKTIFWNEL..............
A0A433WC43_9BACT/2-202 .......n-LSVFITTLVRENQVTVAT..GM..HA.FSREELAESV.....PLLQNYYQHDIADM..P.DIAPEFAAHSALQAAQYIYRIASLTQSRQYSAATLRD.LLP...ILSS.......ATGPAD....IYSADLCLRYLPDLISLAKGLPATDPLMIHMKEMAARWPFSSTGM.........NILPLE-...GVGIITGHPSLLQAYADRIIASKDIQRC.D.DP.QVM.AAVTASLGNYADLLWPGF..............
A0A848FLL3_9BACT/2-201 .......f-LSGFTNELINTGRVSVAG..SL..IS.FEEEDKRDTV.....ALLENYYRQIALDC..P.GTVPAFMPDVAVKAAAYFYSAVQLVILRDVKNEALLE.YLQ...AF-S.......PASPED....HFSADLVFNHLPALLDLAFGLAPADILVTQLKQMAVQWPLSSVGI.........ELETVP-...DDTMLFSHPALQQLYIDRIIAQKDKWRA.S.SP.HIK.QYITETTGEYTHIFWPEF..............
A0A4Q2XZJ5_9BACT/26-231 ....pvih--------LRGRSEGLAAL..EQ..IE.TEADGDPELR.....RLLGSWHQETALDI..G.GPALPFDETAARRGVRLLFRTAWCYLNRDTGKEEVAR.LLL...DPAAh.....pGDSAAA....QFSADVTLQHLPAVFRMAQALSPGDPLLAALRRLARLFPLSGVNIqpe...rppTEEMPTA...TWGNLQSHSGLRQLFLDRILTTRAGHWL.D.HP.ETS.LAIRHSLGEHYQTLVPA-f.............
A0A5K7XHC4_9BACT/2-201 .......n-LCEFLQDLFEGRRTRAA-..AP..YD.LSESELQETR.....EFLANFEEAYRLNL..P.DAPPRFDVEAALWATTHYYKACQYALFRDYGPDFAFT.PAN..qAIAA.......LNSPEA....HYSVDLAFRFLPDLLSFCRSA-TDDPLRQELLEWARQWPLSSVGI.........IEAPEV-...DIAPLLGSASLMQMYADRAIESGDVRAM.Q.SV.QGA.QAIEESLGLYQELAP---elm...........
A0A495IYP9_9SPHI/2-201 .......q-FSEFLNSLFSEGRVTVAR..AL..AD.FNAADLEASA.....RLIAELDRTERLEM..P.AELPGLNKDAALWAAQYLYRSIQFVLLRELEAELMEN.YLQ...PYTG.......TLDDSA....MWSVDLLFRHLGPLFKFSSGISPDDPLVQRLKETAAAWPLSSVGL.........NIQTIA-...DTQPILNNAALKTIYLDRIIAHRDLTRL.G.ER.E-Q.VALTETMGLYQEQFWPG-l.............
A0A8J2XRH8_9BACT/8-210 .......h-FLDTIRHLRNHEEMVIYD..RF..TPnNKKADEEGVT.....EFLRMQYERESLEY..P.GVPPAFEREAACWSARIVYTAAQFLLFREKEVAGVRE.HLP...PYAG.......VVTPGA....ILSADVCLRFLPGVIEKAKELNPEDWLIVILEQHLRVWHYSGIGY.........PLDPTVL...AWEVMAADDCVRQLYVDRVIARKVKALA.E.LP.VLR.RDVDAALGDWGGYFWKEL..............
I4ANR1_BERLS/4-222 ........YFSKTIEHLRHYEEVFLFG..NL..LS.ISESEKESVI.....DLLEIEYKIESVEY..P.QPVLIFDKDAAFWAAKIVYMAAQFMLYRETEVKDLPL.LFS...SFNGnnseyqsKLTASQ....MLSADLCLRFLPAILINAQVIDPEDELIAILEKELIKFHYSAIGYgfrf.ekkeEIQKTILd.sDLELLFSDKSFLQLYTDRVFEKKELNFA.L.FP.PIK.RQLKSNFGIYGNEFWKEF..............
A0A0C1IEN2_9BACT/8-207 .......r-FLDAIYLLRTEESLTLHN..GL..HQ.ADTNEDSIVM.....DFLLEEYERERLEY..P.GTPPAFNAAVALWGARTCYFAAQLLLFRKHAPEEISS.LLP...SYEG.......EITAAA....MLSADLCLRFVPAIAHKAAAIDPNDPLVPLLVKHLETWHYSGLLL.........NQPPANP...DLVTVTGDACLQQLYVNRIIETRNQKLA.E.TP.PLN.KEINATLGNHRDTFWN--..............
A0A0M9DT48_9BACT/1-199 ........----MLKTLREKEEVILYN..NL..LD.IPQQYVQEVL.....EYLADEYNREKIDY..P.YPAPPFDKYAAQWGMYVTYFATQLILYREHKSKDLDI.LFT...QFQN.......RITAES....VLSADICLRFIPQIIYELNLIDIEDPLKKKLENILHIWHYSGLEY........tSLDSENL...DFSVITSDPCLLQLYVDRIIRFKNKSVA.C.HP.AII.HHIKSSLGLYHQDFWKDL..............
A0A1A7KFT6_9FLAO/6-207 .......p-FLDTLFLLRKEGALTIFS..DL..KI.LTKKEENEAE.....DFFESEFEKERLDF..L.SDKIPFNKEAAIWAAKILYHSAQLYLIRKDTAKDLEK.LIP...QYQG.......EKDVSA....ILSADLSLRFLPQLFDALQVADSTDPLVKLLENILHQFHYSGIGL.........DLNLEKI...NWEEELKDKTYRKLYLERIVEKKAYKLA.E.IP.YIN.QLLIAEFGMYKDTFWKEL..............
A0A2T6DBS2_9BACT/2-213 .......e-LASFLTILLERGVARVGT..GF..FA.TPARD-ADAE.....RIVEDMDFFARANC..P.GTAPPLDVKAAVWAAALLYRACQFLHARELDMDIIAP.AMR..ePCPC......pPELPAT....IYSVDLTLRYLPDVLRIAAKLAEDDPFLPLLHALARDWPLSGVGCatitpaaadAGAPAAR...SLDAVLGNAALAALYRDRIITWNDKARLlD.DA.RVR.SLVSAALGGHPELAP---dl............
A0A142XHS1_9BACT/3-200 ........PFHDWLDRVLDSGESVQDA..P-..LH.LAPAERTAVE.....GRLRSAFNLHALDV..A.GPPVAFDPDTALRAATALARACWLLVGAEENEPVALI.LPP...----.......TEAPAA....NLSADVTLRFMPAVYRRARVRDPESPLVTELDRLLRAWPLSGVLA.........DLDGAAT...APLDFGGHAGLQLLYAERLVVTARPGWI.P.PD.GPArAWAERIFAERGTQLPVE-l.............
A0A316ECF5_9BACT/4-205 ........YFLMMLTAIREREEVILYD..NI..LQ.TSEQEQHQVI.....DYLSQVYHQESLEY..P.HQIPPFDAHAGLWAANTLYVSAQLLLYRKNSNDDLSA.LLP...HFMY.......PKTPSA....VLSADLSLRFLPDVITHLDRINPEDELIPILENHLYSWHYSGINY.........PLLVEKL...DFTIEQSDRCLQQLYANRIIKYQRKPLA.E.TI.AFS.EIVGASLGDYRKSFWVN-y.............
A0A6N4SRM9_CYTH3/5-207 ........YFLEMIRTLRKQEEVILYG..NI..VH.INEKYTGAVV.....EFLQKEYQKEILEY..PdHNLPAFETEAALWAAQTIYTAAQLLLYRENKETDLEQ.LLP...DYNI.......TRTASA....VLSVDLCLRFLPDILVQLKMIDSEDSIIEILERKLIYWHYSGINY.........TLPLQLL...DFNSMFIEHALKSIYINRIITYKKLDLA.N.QD.ACK.DTVAAHLGLFAEQFWKEF..............
G8TQB5_NIAKG/1-185 ......ma------------------G..QV..IP.FTQEDTQQTT.....EHLRAYYDNQLSEL..T.GPVPAFQPEAAVWAAIYLYRAVQLTVLRELGEDAVNG.LLT...SFTG.......AVSPET....ILSVDLSFRYLPNLLGLARGLAPEDVLVKQIQAAAIQWPFSSVGM.........KVTGEM-...NVEVIMNDACLRRAYIDRIIEARDRSRC.N.ND.LVN.EYIREALGDHGQTFWPDW..............
A0A7R9LJ36_9ACAR/828-1029 .......p-FLDTIFLLRNSGSMTVFS..NL..QE.ISKKEEQEAG.....DYFETEFEKERLEF..L.SADIKCSKEAAVWGAKVLYHSAQLYLIRENTAKDLDK.LIP...KLKG.......PSDVST....ILSADLSLSFLPQITSVLQTADPYDPLVKTLEDILTQFHYSGIGY.........PLNLEKV...DWEKELQDKTYRKLYLERIVEKKAYTLA.E.IP.YIN.KLLIADFGLHKDRYWQDL..............
A0A495J5L9_9SPHI/2-202 ........KLSEFLTRLFSEGVVDVPR..EL..VD.FEGADLLISV.....DLIRQYEAAMRMEM..P.AQVPELNTDAALWAAQYLFRAIQLVLLRELEAEVIPV.YLS...PYGG.......EADASA....IYSVDLLFRHLRPLFQFSSGISPDDPLVLALRKTAASWPFSSVGF.........KVETMI-...NTDRILNDSCLRLMYLDRIIAHRDRGRL.K.SD.AEI.TALTEVTGMHQELFWPG-l.............
A0A1T4TKU9_9BACT/2-202 .......n-LSSFITTLVRDGQVTVDT..AA..HS.FSKDDLTATR.....NVLLHYYQHDLTDM..P.GEAPAFDSDTALWAAGFIYRAAQLIRFRPCGNTGIEE.WLP...KHAV.......ATGPEA....VYSADLCLRYLPDLLSIAKNLAPADPLVQRLTDIAAQWPFSSTGM.........NIYPAT-...PIAVITEHPSLLQAYTDRIIASKDTGRC.N.DP.VVM.TAVKTSLGSYAHLLWPGF..............
A0A345H5G0_9FLAO/21-224 .......n-ILQTIHHLRTSGQFVLYT..SE..PK.VTTSELNDVT.....DFLAQEYENESLNY..P.FDAPLFDKETATWAAKTIYYAAQFLAHRLEEPKNLNK.FFE...DFKG.......ELTPSV....CLSADISLRFLPFIIKELEHIDFDDWLVKLLKTQLEKFPYTTIGH.........DLDLEIKe.eKLASLFQNNCFRTLFIDRVIAQKDISLT.A.HK.IIQ.ENVAIHLGEHAQQFWSAF..............
B4D8S9_9BACT/2-197 .......d-LPEFLIQLGENGLAVVSD..Q-..--.--ETIGGAVE.....EIVRGWDAVQRQNL..P.GTAPDLVPAAATWAAIRLYRGCQALVCREIPPAEMAA.FLR..ePCPC.......PESPAV....DYSVDLVFRFLPDLLAIARRVSTDDPLVTELLALARAWPLSSVGM.........EGVGTV-...NAARLLRDPCLRQLYIDRILLSGDTARL.N.DD.AVR.AAAKAALGAYPELAP---ei............
A0A2M9BPV6_9BACT/2-202 .......l-LTSFLQDLLTTGSVTLVG..RP..SA.FAPDDLLAAT.....ELLQAYYAADAREI..P.YSAPAFDAPAALWAAGLLYHTVQLTLVRELDEAVIAE.TLP...DFAG.......LITPEV....LYSADLLLRYLPDLLRLAKGLAPGDALVARLQALARQWPLSFGGP.........ELPEPA-...AEARVLDHPALRQEYVDRLIRAQDRRRA.G.QP.HLR.ALVQAALGAHAATLWPDF..............
A0A1I3E1J3_9PLAN/6-204 .......v-IAEVFEKLFLDGQLIVPS..EV..IP.TQQHIRDAVA.....SLLRLE-QDYREHL..P.GRPPAPNPQAMEWSVRQFYSFSQLIAFRHLESSSATR.LEL...DAPF.......TPDPEN....CYAVDLLFRFLPDLARMTRSMGRA-PLQAALTKWGNDWPLSSVGM.........ADLTPR-...SVEGFFSHPGLRNLYVDRIIETQDVSRL.A.DA.GAR.EAVRAALGLHQNLAP---qla...........
A0A518DAE6_9BACT/1-200 ......ml--SPFVDDLLNGRPVRV-G..PP..QA.ANRLDLQAAA.....TRLEAFEREYRLEL..P.GDPPGFDPAAALWAAVSLYLASSLAIHRDSELSAING.AAP..sPLPD.......RMRAAS....HYSVDLTMRFLPSLLKLAKRASSDDPLLGRLMQWGRDWPLSSVGI.........AGIGDV-...DASTLRTSPTLLRLYSDRILASGDASRL.N.DA.TVR.RAAAAAIGDYPELS----pai...........
A0A6M5YXZ0_9BACT/3-198 .......s-FPEWLERLLSTGESVQDG..P-..PS.LVLSERRSVE.....GRLRAAFDQHALDV..A.GPPIAFDPDAALRAAEVLARACWLLVSGDEGTRPALA.LDP...----.......ARAPGA....NLSADVTLRFLPVVHRRARARGPDGTLVIALDRILRAWPLSGVLA.........DLDGEP-...VTAPDFGHPGLQLLYAERLAATGRAGWV.P.ATgPVR.EWVERVFAER--------gvpvpvp.......
A0A5Q3L9V8_9BACT/1-169 .......m-LSPFIQQLWKSGRVRVGG..EL.dVP.PLEEEQAASEkelclTLLQNWEAIVRVDY..P.GEPPRFLPQVALDAVPMFYLACQFLVNRHHPPELLDE.KFQ..vKAWA.......SKTAEE....HYSRDLVLRHLPDLYHQAEVACPGDPLTKKLKAACEVVPLSTVGI.........PIKVSD-...EP--------------------------.-.--.---.------------------eplreserlle...
A0A0C1G0U7_9FLAO/7-208 ........PFLDTIYHLRTIEQVILYD..KV..IT.ISKEEEIDVI.....SFLETEYEREILDY..P.GIAPRFNSAAALWAAKTVYLAAQLLLYREHNSNDLAV.LLP...DYNG.......KLDASA....ILSADICLRFLPQIIMEMQRIDPEDLVIPILEKHLFRFHYSAIGF.........EVDIQKI...DFEILDTNDCLHQLYIDRIVQRKAIKFT.E.SD.FIK.KQLEIGFGDYRKIFWAQL..............
A0A6B9ZGS1_9BACT/2-202 .......t-LSEFISSLINKGEVIVAP..AL..QP.FDTDDLRVAR.....IHLEQHYTDDVSEV..P.GQAPAYDPEAAIWAAGYLYRTVQFLLLRHLDASDIEA.HLP...PFTG.......VQTPAA....IYSADLCLRYLPDIFLLAKGISPEDPLVVTLQAMTLQWPLSAAAI.........PGVVSA-...DLSAVLQHPSLTRMYTDRIILAKDFDKC.T.HP.ACL.PLVAEALGAYSAKFWPQF..............
A0A8J8KCH6_9FLAO/7-208 .......p-FLDSIYQIRTEECLIIYS..KI..LD.ISQKEKDNVV.....EFLMNEFDNEKINY..P.FQSPKFNAKAALFGAEILYHAAQFVAIRENTEKDFKK.NFP...IFEG.......IADESA....MLSADLCLRFLPIVFQQLKSIDDHDPLLEILINIFQKFHYSAVGL.........NIDFPEI...NWENTIMSSCFKMLYLNKIFEYKNYELA.E.NP.FWK.KEILANLGDYKNVFWREL..............
A0A5B9W5U5_9BACT/134-332 .......q-LHEFLDGLLREGNVVFRS..RP..-G.PAEGPSAEVT.....ALLAEAYETHRLDV..A.GPAIPFDAGVACEAAEVVRQACWAMVNQGDRVEDLAA.RVA...MRRT.......PGGPSQ....HLSADLLLRYLPGVHRRARASGPDDPLVGMLAEVLRRWPLSGVLA.........GLEEPPL...TPTNLGGHPGLLMLYAERYAARGRPAWE.P.ER.AGK.DY----------------lelvrqaagrgasp
A0A4R1ADS2_9FLAO/1-200 .......m-LIDFVKDLFETGKIKVAK..EM..TD.FSENDKEIAL.....EILSRYFETYSKQF..PnSHTLNFNVDTAFWAIDYLYKLCQVLLLRELSDEQVLN.YLP...KYAH.......KQSRNE....VFSVDLIFQFIPELFRISKELSPADVVTHEMKELANTWSFSLFEI.........AENMQV-...--GYIENDSVLLDVFCNRIIEKNYTKAI.I.SE.TIK.NNVLTHIGNHSNSFWKE-i.............
A0A1I0R791_9BACT/2-202 .......e-LTNFIAGLINDGKVKVVS..QL..LP.FEAEDLRLST.....VHLQQYYEDDIQEM..P.ATAPSFDENAALWAARYLYTAVQFILLRNLDETTMQE.QLL...PYSG.......EQTPAA....MYSADLTLRYLPDLFDLAKGLSPNDPLVKLMKETAQLWPFSSAAI.........SMSEST-...DLSVIFSDASLKQAYIDRIITARNLHKC.Q.QP.DCY.PLVLEALGAYAADLWPQF..............
#=GC seq_cons .........h.phlppLhppuplhlhs..ph..hs.hstp-hppsh.....phLpphappcth-h..P.ussPsFcssAAlWAAphlYpAsQhllhRc.sspslpt.hls...shss.......shssus....hhSADLsLRaLPslhphucslsssDsLlttLpphhppWPhSulGh.........slshss....shshlhscssLpplYlDRIltppchshh.s.ps.tlp.phlptshGtatphhh.t...............
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