#=GF ID   mCpol
#=GF AC   PF18182.5
#=GF DE   minimal CRISPR polymerase domain
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Laks
#=GF GA   26.40 26.40;
#=GF TC   26.50 26.50;
#=GF NC   26.10 26.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0276
#=GF RN   [1]
#=GF RM   26590262
#=GF RT   Comparative genomic analyses reveal a vast, novel network of
#=GF RT   nucleotide-centric systems in biological conflicts, immunity and
#=GF RT   signaling.
#=GF RA   Burroughs AM, Zhang D, Schaffer DE, Iyer LM, Aravind L;
#=GF RL   Nucleic Acids Res. 2015;43:10633-10654.
#=GF DR   INTERPRO; IPR040942;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Minimal version of the CRISPR polymerase domain. Predicted to
#=GF CC   generate cyclic nucleotides, potentially sensed by CARF domains
#=GF CC   which in turn activate various effector domain including HEPN
#=GF CC   RNases, CARF sensor and effectors are found in conserved genome
#=GF CC   contexts. Part of a broader class of conflict systems reliant on
#=GF CC   the production of second messenger nucleotide or nucleotide
#=GF CC   derivatives. Implicates CRISPR polymerase of the Type III
#=GF CC   CRISPR/Cas systems in a nucleotide synthetase functional role
#=GF CC   [1].
#=GF SQ   111
#=GS D7CYE3_TRURR/246-358      AC D7CYE3.1
#=GS A0A1I7IDS0_9CLOT/262-372  AC A0A1I7IDS0.1
#=GS E8N1D6_ANATU/327-448      AC E8N1D6.1
#=GS A0A7C8HE19_9FIRM/255-359  AC A0A7C8HE19.1
#=GS A0A2P1PLD8_9GAMM/6-120    AC A0A2P1PLD8.1
#=GS A0A5C8IUU7_9BACT/7-123    AC A0A5C8IUU7.1
#=GS Q8YWV2_NOSS1/365-482      AC Q8YWV2.1
#=GS A0A3A9UF40_9FLAO/6-122    AC A0A3A9UF40.1
#=GS A0A0H5CSZ4_9PSEU/1-36     AC A0A0H5CSZ4.1
#=GS Q1CW29_MYXXD/322-436      AC Q1CW29.1
#=GS A0A1J1LSG6_9CYAN/286-386  AC A0A1J1LSG6.1
#=GS K9YJB9_CYASC/269-381      AC K9YJB9.1
#=GS A0A0M8K4X0_9CHLR/316-437  AC A0A0M8K4X0.1
#=GS Q1IZS0_DEIGD/248-359      AC Q1IZS0.1
#=GS A0A8J3IE70_9CHLR/371-493  AC A0A8J3IE70.1
#=GS A0A3N0CPK4_9ACTN/10-116   AC A0A3N0CPK4.1
#=GS A0A1Y0RJS8_9CYAN/7-123    AC A0A1Y0RJS8.1
#=GS D1ADB3_THECD/1-101        AC D1ADB3.1
#=GS A0A1Z3HJG7_9CYAN/5-121    AC A0A1Z3HJG7.1
#=GS A0A0V7ZXD3_9CYAN/265-400  AC A0A0V7ZXD3.1
#=GS A0A1I6UK08_9PSEU/371-485  AC A0A1I6UK08.1
#=GS A0A3G3H1P4_9BACT/323-450  AC A0A3G3H1P4.1
#=GS A0A2H5YYR7_9BACT/342-460  AC A0A2H5YYR7.1
#=GS A0A286EDA8_9NEIS/330-448  AC A0A286EDA8.1
#=GS A0A2V1HDQ2_9GAMM/3-116    AC A0A2V1HDQ2.1
#=GS A0A399EZZ3_9DEIN/257-368  AC A0A399EZZ3.1
#=GS A0A0N0Z2A9_9BACI/285-399  AC A0A0N0Z2A9.1
#=GS A8UTQ8_9AQUI/372-498      AC A8UTQ8.1
#=GS A0A081CAK5_9BACT/339-465  AC A0A081CAK5.1
#=GS A0A0M2UWI2_9BACT/319-444  AC A0A0M2UWI2.1
#=GS K9VAK3_9CYAN/283-385      AC K9VAK3.1
#=GS A0A562R2Q4_9DELT/329-452  AC A0A562R2Q4.1
#=GS A0A078KTA6_9FIRM/332-438  AC A0A078KTA6.1
#=GS A0A2U1K823_9BACI/272-393  AC A0A2U1K823.1
#=GS A0A443IJP3_9RHOB/3-117    AC A0A443IJP3.1
#=GS A0A2H5Z6E2_9BACT/338-452  AC A0A2H5Z6E2.1
#=GS A0A495KQE7_9FLAO/5-121    AC A0A495KQE7.1
#=GS F2NKI1_MARHT/330-447      AC F2NKI1.1
#=GS A0A399F5X1_9DEIN/318-436  AC A0A399F5X1.1
#=GS A0A0N1J1B9_9DELT/2-110    AC A0A0N1J1B9.1
#=GS A0A2K8T5K2_9NOSO/7-123    AC A0A2K8T5K2.1
#=GS A0A8K2A9B0_9CYAN/275-361  AC A0A8K2A9B0.1
#=GS C7LVI8_DESBD/3-111        AC C7LVI8.1
#=GS A0A1C3EA62_9GAMM/2-116    AC A0A1C3EA62.1
#=GS A0A096BER3_9FIRM/328-448  AC A0A096BER3.1
#=GS A0A399ET11_9DEIN/257-368  AC A0A399ET11.1
#=GS L0L254_METHD/3-114        AC L0L254.1
#=GS A0A8J7J3D3_9CYAN/17-132   AC A0A8J7J3D3.1
#=GS A0A1V1P7H9_9DELT/364-478  AC A0A1V1P7H9.1
#=GS A0A564WES5_9PROT/396-493  AC A0A564WES5.1
#=GS A0A7X3MIB5_9FIRM/2-58     AC A0A7X3MIB5.1
#=GS A0A2T1C437_9CYAN/377-492  AC A0A2T1C437.1
#=GS A0A8J6V243_9CYAN/7-123    AC A0A8J6V243.1
#=GS A0A1Q8ZGS3_9CYAN/5-121    AC A0A1Q8ZGS3.1
#=GS A0A543J352_9ACTN/15-130   AC A0A543J352.1
#=GS A5I3U6_CLOBH/291-421      AC A5I3U6.1
#=GS C4FJQ7_9AQUI/365-482      AC C4FJQ7.1
#=GS A0A2A6RP87_9CHLR/338-456  AC A0A2A6RP87.1
#=GS Q9KFY8_HALH5/331-454      AC Q9KFY8.1
#=GS A0A328VJM5_9CHLR/399-522  AC A0A328VJM5.1
#=GS A0A7W3TB84_9ACTN/25-139   AC A0A7W3TB84.1
#=GS A0A7S8E5V9_9CHLR/383-504  AC A0A7S8E5V9.1
#=GS A0A2T4VM57_VITXG/316-426  AC A0A2T4VM57.1
#=GS A0A5C6M697_9PLAN/2-127    AC A0A5C6M697.1
#=GS A0A0F3GNU5_9BACT/377-494  AC A0A0F3GNU5.1
#=GS R4YMD8_OLEAN/1-89         AC R4YMD8.1
#=GS A0A8A7KF09_9FIRM/334-455  AC A0A8A7KF09.1
#=GS A0A2S1JM62_9GAMM/23-136   AC A0A2S1JM62.1
#=GS A0YRL7_LYNSP/269-402      AC A0YRL7.1
#=GS A0A7Y0JTD2_9ACTN/374-488  AC A0A7Y0JTD2.1
#=GS K9X189_9NOST/7-123        AC K9X189.1
#=GS Q8R6Z3_CALS4/669-772      AC Q8R6Z3.1
#=GS A0A5A5TG43_9CHLR/357-477  AC A0A5A5TG43.1
#=GS A5D0V5_PELTS/328-451      AC A5D0V5.1
#=GS D4E431_SEROD/2-115        AC D4E431.1
#=GS A0A139X1Y9_9CYAN/298-398  AC A0A139X1Y9.1
#=GS A0A6F8YIE3_9ACTN/6-120    AC A0A6F8YIE3.1
#=GS I5B4K5_9DELT/331-450      AC I5B4K5.1
#=GS A0A1C0A8F1_9FIRM/336-457  AC A0A1C0A8F1.1
#=GS A0A161TUI5_9NOCA/2-116    AC A0A161TUI5.1
#=GS A0A367QYT4_9NOSO/5-121    AC A0A367QYT4.1
#=GS A0A0V7ZSX6_9CYAN/29-145   AC A0A0V7ZSX6.1
#=GS A0A1H9HC49_9BACT/311-429  AC A0A1H9HC49.1
#=GS U5QRQ1_9CYAN/254-353      AC U5QRQ1.1
#=GS A0A1Z4UQF6_9CYAN/277-413  AC A0A1Z4UQF6.1
#=GS D7BJ36_MEISD/260-371      AC D7BJ36.1
#=GS A0A0M9E5D6_9DELT/1-75     AC A0A0M9E5D6.1
#=GS A0A0P6YJM1_9CHLR/326-447  AC A0A0P6YJM1.1
#=GS A0A3N6PLR1_9CYAN/241-300  AC A0A3N6PLR1.1
#=GS A0A7U9PTB1_9CHLR/325-446  AC A0A7U9PTB1.1
#=GS A0A2P7TSS7_9SPHI/345-482  AC A0A2P7TSS7.1
#=GS A0A6C2D553_9RHOO/3-117    AC A0A6C2D553.1
#=GS A0A1M6LSY5_9CLOT/291-413  AC A0A1M6LSY5.1
#=GS A0A0F5Y8L0_9CYAN/385-502  AC A0A0F5Y8L0.1
#=GS A0A367RV09_9NOSO/5-121    AC A0A367RV09.1
#=GS A0A0D0S9W7_9FIRM/103-213  AC A0A0D0S9W7.1
#=GS A9AVY9_HERA2/348-467      AC A9AVY9.1
#=GS B1I5L0_DESAP/328-449      AC B1I5L0.1
#=GS A0A3M0BR48_9AQUI/388-515  AC A0A3M0BR48.1
#=GS A0A2H5YTS1_9BACT/337-452  AC A0A2H5YTS1.1
#=GS A0A1H3PQD3_9CLOT/295-411  AC A0A1H3PQD3.1
#=GS A0A2K2TT40_9CLOT/309-418  AC A0A2K2TT40.1
#=GS K9PDQ1_9CYAN/274-373      AC K9PDQ1.1
#=GS A0A165YSQ2_9BACI/284-394  AC A0A165YSQ2.1
#=GS A0A1W9QCR8_9DELT/332-451  AC A0A1W9QCR8.1
#=GS A0A1X7LP33_9BACL/358-476  AC A0A1X7LP33.1
#=GS C8PFL6_9PROT/265-382      AC C8PFL6.1
#=GS A0A1M5A1B6_9BACL/361-472  AC A0A1M5A1B6.1
#=GS A0A3N1AX98_9ACTN/6-120    AC A0A3N1AX98.1
#=GS A0A251WM42_9CYAN/279-413  AC A0A251WM42.1
#=GS A0A1Z4J2K6_9CYAN/7-123    AC A0A1Z4J2K6.1
D7CYE3_TRURR/246-358                 ..........i-LIADGDNMGKLL....S---...ARE..S...EEA......H....HELSR.RLD.D.F.A.ER.ARDI..VKEH-.....SGMAVF..AGGDDVLAL.L.PVTTa.........lACGQEL.SET....FKHTV................RGTLSTG...I..AIV......HyrEP..LS..ISLNHARAA.EKR-----akav......................................................................
A0A1I7IDS0_9CLOT/262-372             ..........l-VQIDGDSMGKVI....KNLT...---..N...NDK......C....KKFSK.KLL.E.Y.S.KD.AVTI..INNY-.....GGFPIY..AGGDDLLFF.A.PIKN..........sKSESSS.NNI....FQLFN................-------...-..---......-..--..--..---------.--------eldfkfnekfkdykesnpsisigmevfhqkypl.........................................
E8N1D6_ANATU/327-448                 ...........LIQFDGDGVGLKI....DYLLq.gKEK..A...EAN......H....RCFSE.NIA.V.F.S.KK.VQEI..VKPEE.....GGFLIY..NGGDDVLFL.A.SREKg.........lELARRL.AEE....YQNTVgk............dlGILATAS...A..GVV......I..AH..HL..TPLARALSL.MREAE---rsa.......................................................................
A0A7C8HE19_9FIRM/255-359             ........kkl---SDGQGIDKKI....EQET...EKD..S...ITT......F....QEFSS.KLH.Q.F.A.SE.AHRI..IKGDN.....KGMTIY..AGGDDLLFF.A.PV--...........------.---....-----................-------...-..---......-..--..--..---------.--------fskgkhvfsvldeitnefdnqfntsknmedrptlsfgvsi..................................
A0A2P1PLD8_9GAMM/6-120               ...........YVLGDADQIRDGI....DKRL...LQG..K...LEE......L....TAFSS.ALT.K.A.I.AS.LLQS..FEEEM.....GATVIM..AGGDDVLLR.V.SYERy........slDTNLSL.AEE....FHRST................GCTISFG...V..AEK......L..SD..AY..INLRKAKAE.--------kscvcf....................................................................
A0A5C8IUU7_9BACT/7-123               ...........YIRLDVDNAGDSI....ELAL...LKA..D...YRK......A....QNTHH.KIQ.E.G.I.NL.ILDK..INRLD.....STALLM..RGCDDILFS.I.EKDNy........dfNYLEKI.KSE....FKSTT................GFSLSIG...V..GSS......I..PE..CM..YNLRVAKVS.GKDTVI--en........................................................................
Q8YWV2_NOSS1/365-482                 ...........YYGLDGDDTGKIL....EELF..lSCS..D...ESS......F....RKLSK.DVA.N.A.I.SK.ISKF..VTDKL....gKNAVVF..EAGDDLLFK.G.NLQE...........DMLFEM.QAM....YSQLT...............pGLTCSIG...Y..GRS......F..QE..VY..LALKLAKTQpGKNAIVGI..........................................................................
A0A3A9UF40_9FLAO/6-122               ...........FIRLDVDNAGDSI....ELAL...LES..D...PKK......A....QHVHD.MIQ.E.N.I.NL.IVDM..IQEKH.....TRVVLM..KGSDDILFS.V.NKNEf........diNFLKKV.KSE....FKLRT................GFSISIG...V..GST......I..TQ..CL..LNLRIAKVS.GKDKIV--es........................................................................
A0A0H5CSZ4_9PSEU/1-36                ........mrn-------------....----...---..-...---......-....-----.---.-.-.-.--.----..-----.....------..---------.-.----...........------.---....-----................SFSISCG...V..GAD......S..RQ..AL..LALRLAKSS.GKNRTS--ka........................................................................
Q1CW29_MYXXD/322-436                 .........cl--VADGDRMGRAL....EALA..rQPD..G...HAA......H....QRISR.ALA.D.F.T.RQ.AKTI..VEVEH.....RGVLVY..AGGDDLLAF.V.TPMDala.....caqALAVAF.RAT....LEAALagtr........aevpTLSVGLG...I..GHV......L..--..--..---------.--------eslgell...................................................................
A0A1J1LSG6_9CYAN/286-386             ..........w-FMGDGDKVGDKL....KEIA...EED..G...DQG......L....QEFSK.AMR.K.W.G.KN.FTRE..FAKKK.....LGRIIY..AGGDDFLGV.I.YSRN..........pK-----.---....-----................-------...-..---......-..--..--..---------.--------qpisrqtvldwlmelpqewakheqaitlslgl..........................................
K9YJB9_CYASC/269-381                 ..........w-FMGDGDKVGDHL....QELL..aKPD..G...EKE......I....EKFSH.AMR.K.W.G.DN.LSNN..FPRD-.....LGRIIY..AGGDDFLGV.I.YSKK...........KNVDDS.QEL....KKKA-................-------...-..---......-..--..--..---------.--------lqwlsnlkeewqkhdqditlsvgfvwvagsvpq.........................................
A0A0M8K4X0_9CHLR/316-437             .........ll--LADGDSMGKAI....DAQT...---..S...PAA......H....RALSQ.KLS.E.F.A.QE.VPKI..VRQY-.....RGVPVY..AGGDDILAY.L.PLHTa.........lECVREL.AET....FQEMMsaftf......dengqQKSPTLS...A..GLV......I..TH..HL..EPLRDALAL.VRAA----eksa......................................................................
Q1IZS0_DEIGD/248-359                 .........il--VADGDSMGALL....SA--...-HD..S...EAA......H....HELSR.RLD.E.F.A.RQ.ARRI..VQKH-.....DGQAVF..AGGDDVLAF.L.PVTTa.........lACGREL.AEK....FRHTV................RATLSAG...I..AVV......-..--..--..---------.--------hyreplstslrqareaekvakk....................................................
A0A8J3IE70_9CHLR/371-493             .......yail--VADGDGMGEVI....DHQA..hLG-..-...IDK......H....RQLSR.ALA.L.F.S.GG.VRET..VRKH-.....RGALIY..AGGDDVMAL.L.PLHSm.........lACVQEL.AEN....YQTAMrlf.........kneqGKQSTLS...A..GVA......I..VH..HL..ALW------.--------qealdvardaesra............................................................
A0A3N0CPK4_9ACTN/10-116              .........va--IADGDEVGALL....DTFA...TVN..D...LDG......L....VRTSR.QID.S.D.R.EH.LSRW..FIDL-.....GATVAL..TVADTVIAS.G.GGEP...........PGAAQY.PS-....----F................DPTWSVG...V..GVD......I..AG..AR..AALAVAKAL.GRNRVI--d.........................................................................
A0A1Y0RJS8_9CYAN/7-123               ..........v-CVGDGDNIGDVI....DFHL...LSG..N...LEE......A....SKFSF.QVK.S.A.L.ED.IATL..AKSQI.....KASLVY..VAGDDICFI.V.SDDLk........itDVLTSY.SEY....FLKKT................GKTMSFG...V..GRT......S..VE..AL..ISLRTAKVS.GKGRVIA-f.........................................................................
D1ADB3_THECD/1-101                   ........myv-------------....----...ITE..N...KNK......L....RELSQ.EFE.N.L.I.NE.LFNQ..INKNP.....SIKVLL..HGGDSILLE.M.PRSE..........iETTVNL.IRT....TSRGT................SFTFSGG...Y..GKT......M..RD..AY..LALKLAKAT.GKNKII--pf........................................................................
A0A1Z3HJG7_9CYAN/5-121               ...........YFAADGDDVGHHL....EYLM...LRN..E...SAK......I....FEFSK.VFH.K.A.M.LW.LEYE..LIESC.....EAEIIF..TGGDNILAR.I.SKTDd........tlNLIEKI.RFE....FQKKA................KSTLSIG...L..GKT......P..RE..AY..FALKLAKTS.GKNCVRQ-f.........................................................................
A0A0V7ZXD3_9CYAN/265-400             ..........w-FMGDGDEVGKYL....KKLA..kQEN..E...EVS......V....KKFSQ.DMR.E.W.G.KN.FYRA..FPQD-.....LGRVIY..AGGDDFLGV.IySKQN...........EDEIQP.QRA....FDWLKslpeew....kknkhkDITLSVG...-..---......-..--..--..---------.--------fiwaghsvpqrdilqhcreaekhakslgrdritir.......................................
A0A1I6UK08_9PSEU/371-485             ..........i-AIVDGDDIGNQM....EHRL...LTG..N...VED......A....ADYSH.SVT.T.S.L.RA.LVDD..VQEID.....GARLIS..QGGDSAIFE.F.PADK...........--RAEF.EQV....LHRIRi.............nrTFHVSCG...Y..GAT......S..KE..AF..MALRLAKTT.GKNSTV--nh........................................................................
A0A3G3H1P4_9BACT/323-450             ..........v-LTFDGDSMGKWL....GGAN...VNG..S...LEA......F...hEDFSK.HLS.A.F.A.KK.ADEI..VKKEV.....KGYTVY..AGGDDYLGF.A.NINHl.........fGVLQEL.QEA....YKTEVsnplat....yrkdgkEITFSAG...I..CIA......-..--..--..---------.--------hykeplrlvlqqahtmmdkak.....................................................
A0A2H5YYR7_9BACT/342-460             .........vl--VLDGDSMGQWL....TSAL...GDG..G...VEA......H....REVSR.KLA.R.F.A.GK.AKEA..GRQAA....pDTVFVY..QGGDDVVAL.V.PAEQv.........vPLALAL.AVA....FAKET...............dGRSASAG...IaiGHW......L..--..--..---------.--------eplgdllqnareaekrakrl......................................................
A0A286EDA8_9NEIS/330-448             .........ml--LADGDRMGELL....DKA-...--E..T...QEN......H....QDISQ.NLS.V.F.A.QF.VPKI..MREN-.....RAQYIY..AGGDDVLGL.A.SL--...........NNAVKS.AKM....LKDQFs.............dsLKTISAQ...L..GAE......T..P-..--..---------.--------tlsvglaichiqnplgnirslakraeki..............................................
A0A2V1HDQ2_9GAMM/3-116               ...........YVTIDGDDVGQKI....SASY...LFN..N...VGE......L....VKINE.LVN.Y.A.T.LE.ISEV..LAKN-.....GFELIF..RAADGVAGR.I.---E...........NDSIEL.SEV....FNQIQri...........pcgNITFSMG...S..GRS......L..KD..SY..IALITAKSN.GKNQ----hyn.......................................................................
A0A399EZZ3_9DEIN/257-368             .........il--VADGDRMGELI....S---...RQD..D...PEA......H....RRLSK.SLD.E.F.A.QE.ARKI..VPKY-.....RGFMVY..SGGDDVLAF.L.PVNQa.........vACAKEL.SEA....FRHQV................KGTLSAG...I..AIV......H..YRepLS..ISLENAREA.--------ekaakn....................................................................
A0A0N0Z2A9_9BACI/285-399             .........vl--MMDGDNMGK--....--WF...SGE..R...KEE......Y....SETSQ.KLA.R.F.A.KE.VVPQ..IVEEQ....cHGKLVY..AGGDDVLAF.L.PTETv.........lKAAEEL.RLA....FGDERkg...........lghGATASFG...V..--V......I..--..--..---------.--------ahkksplhlvlnavralekk......................................................
A8UTQ8_9AQUI/372-498                 ........yai-LISDGDSVGDWL....GIKTt.iRKEplS...ENF......H....MVFSK.KLS.E.Y.A.KD.VAEL..WQEQY.....PRLMVY..AGGEDIMAL.M.HPFDv.........vTYASKC.AQM....FKNTVgdl..........akeEKLASIS...A..GAL......I..TH..AK..MSLQKALNE.--------agklekk...................................................................
A0A081CAK5_9BACT/339-465             ..........l-LCFDGDSMGKWL....SGVY...LKD..S...QRKnl.kdfH....QALSA.KLM.G.F.A.KQ.VRKY..FKDHP....hYGHVIY..TGGDDFLGF.V.SLNSl.........lTVMRHL.RAE....FDKLDvsd.........faepDKKLTFS...A..GAV......I..AH..IT..TPLS-----.--------evvkwardmek...............................................................
A0A0M2UWI2_9BACT/319-444             ..........i-ISMDGDNMGNIL....KEN-...RDK..F...PGY......I....QDVSR.IIS.D.F.S.NA.VNAT..VSRN-.....QGQLIF..AGGEDINFV.I.HPEYl.........lDCIGEL.NNL....YNGYFlknd.......ltkpmAEKFTLS...A..GVV......V..CY..HK..YPLSQA---.--------ilsacgmlrkakkf............................................................
K9VAK3_9CYAN/283-385                 ..........w-FMGDGDKVGKKL....QEIA...QKE..G...DEG......L....NKFSE.AMR.A.W.G.EN.FIKN..FPKD-.....QGRIVY..AGGDDFLGV.-.----...........------.---....-----................-------...-..---......-..--..--..---------.--------iyssqrenppepiealewlmglsdewkkhgqdinlsvgfvwa................................
A0A562R2Q4_9DELT/329-452             .........il--VGDGDNMGKMI....DAI-...--K..T...QEG......H....ARFTS.ELS.T.F.A.KE.VKGL..VEGY-.....SGSLIY..SGGDDVMAY.L.PLHKalac..adklrLKFHDS.M--....----Aavhke.....lnlpesVVKPTFS...A..GLA......I..VH..HS..MPLDQALDQ.ARKA----ekma......................................................................
A0A078KTA6_9FIRM/332-438             ..........v-VKFDGDNIGST-....---Y...SNC..S...EEQ......Q....RQLSE.EIG.E.F.A.TK.VPDI..IKEY-.....KGECIY..AGGEDFLGF.F.PVSKa.........iRALMAL.REK....FQEMV................HNTFSAG...I..--V......Y..AH..--..---------.--------lmpplknvlnlademer.........................................................
A0A2U1K823_9BACI/272-393             ..........i-IMMDGDDMGKWIsgidNKILsgfKNI..D...EAY......H....EEISR.RLT.V.F.S.GQsVPNI..VKQS-.....KGRLVY..AGGDDVLAF.V.PLDEl.........lSMIQSL.REV....FSSENg..............lDMKATAS...M..GVV......I..AH..KK..EPLQR----.--------vlttvrele.................................................................
A0A443IJP3_9RHOB/3-117               ...........YVAIDGDDIGGKL....ASSY...LAN..R...VES......L....KATKD.LID.L.K.T.RQ.ISEL..LSSL-.....GYDVLF..CAADGVTGA.L.K---...........ADQINT.SSL....YQKVAli...........ggdDISFSVG...V..GNS......L..RE..SY..VALLYAKST.GKARA---cnf.......................................................................
A0A2H5Z6E2_9BACT/338-452             .........vl--VLDGDSMGEWL....SRAL...AEG..G...EAA......H....QDISQ.KLA.S.F.A.QK.ARQV..FADSF....pNAVPIY..LGGDDVLAL.A.PAEEa.........vPLALTL.AEQ....FHEVT...............gGRTASAG...I..---......-..--..--..---------.--------aiahwleplgdllqaareaekr....................................................
A0A495KQE7_9FLAO/5-121               ...........YIRIDCDNVGDKI....EFAL...YND..D...PET......A....QKISD.SIK.I.N.I.KW.LIDN..MNQIS.....KGKVLL..IGSDDILFE.T.NEEFf........niQKLENL.RQE....FFMKT................NITLSIG...V..GIS......I..ID..AL..TNLNIAKIS.GKNRII--ln........................................................................
F2NKI1_MARHT/330-447                 .........ll--HADGDRMGETI....DR--...-QQ..D...PKA......H....RELSRrQAL.E.F.A.DK.VKRI..VEAH-.....QGGLVY..SGGDDVLAL.L.PLHTa.........lRAAWAL.ARR....FRDVVkpy..........gkpEAPPSLS...V..GLA......V..VH..HL..EPLQDALDL.V-------rraekl....................................................................
A0A399F5X1_9DEIN/318-436             .........ll--HADGDRMGEAI....DHQS...RQG..A...-EA......H....RRLSN.KLAlD.F.A.AR.VRGI..VERH-.....KGCLVY..AGGDDVLAL.L.PLHTa.........lPCAKAL.AQI....FSAAMrg...........fgeKHDPTLS...V..GLA......I..VH..HL..EPLQDALEL.--------vrrtekf...................................................................
A0A0N1J1B9_9DELT/2-110               ...........YLAYDGDKVGRTL....ESLL...IDN..N...ELK......I....EEYAN.TVF.E.A.L.NS.LKSA..LIDI-.....GCRIIF..ASGDSILAT.T.----...........NKYFDS.ELI....KRKYG................NITFSLG...I..GNT......P..LE..AM..LALKKAKSK.GFAECLFY..........................................................................
A0A2K8T5K2_9NOSO/7-123               ..........i-CIGDGDNIGDVI....DFYL...LSE..N...LAE......A....SKFSF.KVK.A.A.I.EK.IAEF..AQNEM.....NASLVY..VAGDDICFT.V.QANLn........ilSNLVCY.SNF....FLKTT................GKTMSFG...V..GQT......S..VE..AV..VSLRKAKVS.GKGRVIN-f.........................................................................
A0A8K2A9B0_9CYAN/275-361             ..........w-FMGDGDKVGDKL....EQIA...QQN..G...DEG......L....KNFSE.QMR.R.W.G.ED.LKSNpnLFPEG.....KGRVIY..AGGDDFLGV.L.----...........------.---....-----................-------...-..---......-..--..--..---------.--------ynhqagkkvepkqawqwlqdlp....................................................
C7LVI8_DESBD/3-111                   ...........FYAIDGDDIGAKL....EKFA...LLG..D...LKS......I....QMLSE.EVC.E.S.L.VQ.LKTY..FEEN-.....SATIVF..CGGDSLLAY.S.----...........KHEIDL.NLE....RLSLG................GLTFSAG...I..GAN......C..CD..AT..LALKKAKGL.GKRRIEV-i.........................................................................
A0A1C3EA62_9GAMM/2-116               ...........YITIDGDDIGQMI....TSSY...LKN..D...LNE......L....SRINH.IVN.E.K.T.IL.ISEF..LKDY-.....GFNIIF..CAADGVAAY.A.EIEK..........vDEVFIF.NSI....KS-IAy..............pQIHFSVG...V..GST......L..RE..AY..IALLSAKSS.GKHC----lhnf......................................................................
A0A096BER3_9FIRM/328-448             .........ll--VSDGDDMGHWL....SGDFl.iDKS..Q...LKT.....fH....ENMSQ.ELG.R.Y.A.DD.IEKM..INKP-.....KGKVIY..AGGDDVLAF.V.NLDYl.........lDTMPSL.RTE....FPQFDkla.........qvkdDIKSSVS...C..GVV......I..AH..--..---------.--------ykepleevlnwarrm...........................................................
A0A399ET11_9DEIN/257-368             .........il--VADGDRMGDLI....S---...RQD..D...PEA......H....RSLSK.TLD.D.F.A.RE.ARNI..VLKH-.....KGFMVY..SGGDDVLAF.L.PVNQa.........vACAQEL.SEE....FRHRV................KGTLSAG...I..AIV......H..YRepLS..ISLQNARDA.--------ekaakn....................................................................
L0L254_METHD/3-114                   ...........YIAIDGDDIHQKF....EKCL...LES..D...EKN......I....VRTSK.EIT.N.T.I.DR.IIDH..LQHE-.....SLRIVF..SAGDCILCK.C.DA--...........VDLIDL.SNY....LDKIG...............nTNTVSVG...I..GDT......L..EK..TY..IAFKYARSI.GKNSIVKY..........................................................................
A0A8J7J3D3_9CYAN/17-132              ...........YAFFDGDNIGISI....ENLL...NNG..K...IKE......A....SRLSE.SIK.F.A.I.FK.IESF..IHLSE.....GANIII..SGGDDILIK.Y.DSEQy........nhQFLEKI.TQI....FSGYT................GLSMSCG...V..GKN......I..SQ..AI..NNLMIVKQT.IKGSI---ki........................................................................
A0A1V1P7H9_9DELT/364-478             ..........i-ISFDGDNMGDYR....KQLQ...LS-..-...-EE......H....KQFSK.KLA.G.F.T.QK.VYQL..IHQSD....yHGYVIY..SGGDEGVLL.V.PLSEt.........lAVMDRL.RKT....FLAET................GLTLSVG...A..AIV......H..HH..A-..---------.--------plgeglkaanealdraklv.......................................................
A0A564WES5_9PROT/396-493             ..........l-LRMDGDNVGTLL....EAL-...---..-...--G......D....QKVSE.ALQ.R.F.T.VR.VQDL..VRKN-.....NGVLIY..AGGDDVLAL.F.PIEDa.........lKAALEL.RRA....YVNAWpg............ddPQTISAG...-..---......-..--..--..---------.--------lvfadhhepfrh..............................................................
A0A7X3MIB5_9FIRM/2-58                ...........YAYFDGDSIGDSI....ELLL...LNG..K...IQE......A....KELSS.KLN.D.A.I.YQ.LKME..MKLMP.....NIEIIL..FGG------.-.----...........------.---....-----................-------...-..---......-..--..--..---------.--------m.........................................................................
A0A2T1C437_9CYAN/377-492             ...........YFGFDGDSTGDYL....DTAF...SQS..S...EDE......V....RQRSQ.IVH.G.A.I.SE.LKKL..ICKETr...dHNSVVF..AEGDNILFK.A.RYQV...........SLLNEL.QRI....YKDKT................GLTGTIG...Y..GKT......L..PE..VA..LAMRLSKAK.GGDSVMG-i.........................................................................
A0A8J6V243_9CYAN/7-123               ..........v-CIGDGDDIGNVI....DFYL...LTN..D...LDN......A....SNFSF.QVK.S.S.I.ER.IAKD..AQVDM.....AANLIY..VAGDDICFV.V.SKKNh........vlDKLKFY.SDL....FFQLT................GKTMSFG...I..GNT......P..VV..AS..ICLRKAKVS.GKGRIVG-s.........................................................................
A0A1Q8ZGS3_9CYAN/5-121               ...........YAFFDGDNIGSTI....EILL...TEG..Q...IEK......A....SNLSK.NIQ.I.A.L.TE.IEGF..LKSKK.....GIEIII..LGGDDILISyS.SLEKe.........eALLEDV.KSR....FLKRT................GNTMSCG...V..SEN......L..SE..AI..WNLHLAKLY.GKNMIKG-i.........................................................................
A0A543J352_9ACTN/15-130              ...........FAYFDGDDIGPRL....ELLL...LDN..K...IEE......A....RQYSL.SIN.Q.A.L.TQ.ARTL..LEDIH.....PVEVII..FGGDDLFVS.W.PDDKv........alSDIENV.KRV....FLEMT................GNTMSVG...L..GRS......P..KE..AM..HNLRRAKLL.GKDKIV--q.........................................................................
A5I3U6_CLOBH/291-421                 ..........i-VQADGDSMGRVI....EKFK...IHN..D...REN......IyvdyKDFSS.KLL.E.Y.D.KN.SHEK..IKKY-.....GGFTIY..AGGDDLLFI.A.PVIT...........KNKNNI.FQL....IDALSglfdn......efkheEEKPTTS...F..GIA......I..VH..HK..FPLYYA---.--------ldeardllfnkakny...........................................................
C4FJQ7_9AQUI/365-482                 ..........i-VVMDGDSMGEKI....SKAF...E--..-...ENK......I....IDITE.KLS.E.F.S.KE.VKGI..VEKY-.....SGISVY..SGGDDVLAL.F.PLETa.........lKGYMEIiSQF....KDKFKdm...........kdaGYNFTAS...A..GLV......I..SH..YK..IPLSYVLQE.ARSA----eska......................................................................
A0A2A6RP87_9CHLR/338-456             .........ll--LADGDNMGLAI....D---...MQN..S...PEA......H....RMVSR.TLD.G.F.A.AR.VREV..VEQEY.....SGALIY..AGGDDVLAF.L.PMHTv.........lGCAQAL.AAA....FQQQMaav..........glgAKTPTLS...V..GVA......L..VH..HL..EPLADALTL.ARRAE---rla.......................................................................
Q9KFY8_HALH5/331-454                 ...........FLVCDGDQMGKAL....RNL-...--K..N...IED......H....QAFSK.KLS.E.F.A.AK.ARKI..VTTDKr...dEGELVY..AGGDDVMAY.L.PLHRc.........lDVAAKL.QQL....FGELMnea.........lpkeAVRPTLS...V..GIV......I..AH..MM..EPMSEV---.--------rklamaaekqakr.............................................................
A0A328VJM5_9CHLR/399-522             ..........l-LQMDGDQMGTII....GEVQ...SQD..D...HRT......I....SRALS.EFA.-.-.R.TH.VPGI..VEDKR.....PGKLIY..AGGDDVLAF.A.PLAHm.........fAMASAL.QQT....YRKIVgssvq......tvskgTRTATVS...M..GIA......V..AH..HL..MPLTLVRRM.ARE-----aeeqa.....................................................................
A0A7W3TB84_9ACTN/25-139              ...........FLALDGDDIGRRL....EFYM...VSE..D...TAG......L....ESFSN.AFG.E.V.V.ES.LKFV..VSESP.....SVDVIL..QGGDSFLLS.A.PLED..........lTRIISG.VKG....VVAET................SFTFSGG...Y..GPS......M..KE..AY..LALKIAKSS.GKNRFNR-f.........................................................................
A0A7S8E5V9_9CHLR/383-504             ..........i-LSMDGDHMGKTL....GNL-...---..D...QGQ......H....EKFSR.TLA.D.F.ArHN.VKNI..VEEEH.....LGRLVY..AGGDDVLAL.L.PVRHalq.....vaeQLRSEF.EKV....VATIGvk...........nhkGEPVTAS...T..GLV......C..VH..HT..HNLQDAVNA.--------annaqkia..................................................................
A0A2T4VM57_VITXG/316-426             .........cl--VADGDKMGETL....HALA...SHG..-...PAA......H....QSLSR.TLS.D.F.A.TE.ARRI..LEERH.....RGVLVY..AGGDDVLGF.V.CLPDa.........lSCAAEL.SRA....FAAAMeqelqs...ragvnapTLSVGLG...V..GHV......-..--..--..---------.--------leslg.....................................................................
A0A5C6M697_9PLAN/2-127               .........il--VADGDRVGQRI....---L...QSK..S...ADE......H....RELSQ.RLS.A.F.A.GS.VRGI..VQQH-.....QGALVF..AAGDDLTAF.L.PLDQaiac..adalrRKFSET.LGA....VDQSQ................SVTLSVG...V..---......-..--..--..---------.--------aighfmesmedllasarlmearaksqpgknal..........................................
A0A0F3GNU5_9BACT/377-494             ...........YFGFDGDATGDYL....ETAFv.mSGI..D...EEE......V....QMRSN.ILR.E.A.I.NK.LKKL..IKKTTk...dHKSIIF..AEGDNILFK.S.KFDN...........TLLNEI.QSV....YKKET................GLSSSIG...Y..GKT......L..RD..VM..IALRLAKAK.NGESLVG-i.........................................................................
R4YMD8_OLEAN/1-89                    ..........m-------------....----...---..-...---......-....-ELSQ.SLQ.I.S.T.EA.ISIK..LQEN-.....GFDIIF..CAADGVVAS.T.----...........ELDVDL.KSI....FSEIRgi...........apeGMTFSAG...S..GAN......L..RE..SY..IALTSAKSN.GKNCM---hdy.......................................................................
A0A8A7KF09_9FIRM/334-455             .........iy--RADIDDLGKWM....SGEY..kSDN..AmglLEY......Q....QQLSN.KID.G.F.L.KE.VRKF..FNENK.....DCLLVY..AGGDDILAL.L.PVRKs.........iELAEKV.YDC....FNKKVkne.........evfkEITLSQG...-..---......-..--..--..---------.--------ifilhykdtlseslqvskeri.....................................................
A0A2S1JM62_9GAMM/23-136              ...........YISIDGDDVGRKI....TSCY...LNN..D...EDK......L....HSVSK.QLE.E.S.T.KK.IADL..LLSR-.....GFDVIF..SAADGVVAR.T.----...........ESDCNF.EEI....FLCICsc...........sskGITFSAG...V..GTS......L..RE..AY..IALLNSKSN.GKNQLSH-f.........................................................................
A0YRL7_LYNSP/269-402                 ..........w-FMGDGDKVGKKL....QEIA...TKE..G...DKG......L....KKFSE.AIR.N.W.G.KE.FMNN..FPQE-.....KGRVVY..AGGDDFLG-.-.----...........------.---....-----................-------...-..---......-..--..--..---------.--------iiysskpekqpepiealdwlmglpeewkkhgqdinlsvgfvwaghsvpqrdvlqhcreaekkaknlgrnrvtir
A0A7Y0JTD2_9ACTN/374-488             ..........m-AIIDGDDVGQAI....ENRM...LQN..D...TDG......V....LDASA.AIG.G.A.L.EV.LGRR..LSIIS.....GVRQLS..FGGDSALFK.V.EGDS..........vDSFLRE.LEI....SRRRV................DFHFSCG...Y..GPD......I..RS..AF..IALRSAKTS.GKNKT---ksf.......................................................................
K9X189_9NOST/7-123                   ..........i-CLGDGDNIGDTI....EFHL...LSG..N...IEE......A....SKFSS.QVK.T.A.I.AK.IAEL..VKDEI.....GASLVY..VAGDDICFV.V.SAEKn........ikDYLVKY.SNF....FLKTT................GKTISFG...V..GRN......S..VE..AL..ICLRKAKVS.GKGHVVTF..........................................................................
Q8R6Z3_CALS4/669-772                 lckkhpttpsl-------------....----...---..-...---......H....QTLSR.KIS.TfA.L.QE.VRRI..VEETH.....YGKLVY..AGGDDVLAL.L.PVEEv.........lECAYEL.QNA....FKEVL................SSEASMS...A..GIV......I..VH..HK..YPLYLALK-.--------evqlaqkka.................................................................
A0A5A5TG43_9CHLR/357-477             .........iv--VADGDRIGEII....DTLA..kQAG..G...YHN......H....QRFSQ.KLA.L.F.A.GE.AKQI..VRKY-.....QGTPIY..TGGDDVLAL.V.PLHKl.........lECTKQL.AET....FQKTLapal........ndidP--PTLS...M..GVA......I..VH..HL..SLLQE----.--------slglarraerl...............................................................
A5D0V5_PELTS/328-451                 .........ll--CADGDHMGKVI....DA--...-QK..T...PEK......H....RELSR.SQS.S.F.A.LE.ARRI..VKEN-.....NGSLIY..SGGDDVLAL.V.PLHKv.........lDCACRL.SKT....FRERLagfkg......edggeEISPTLS...V..GIA......V..AH..HL..EPLSD----.--------vlelarsaekaaks............................................................
D4E431_SEROD/2-115                   ...........YIAIDGDDVGRKI....TSSY...LSN..S...EER......L....KYISN.KLN.D.T.T.IR.ISKM..LLSN-.....GFEIIF..QAADGVTAK.T.----...........DNEVNL.NFV....FDKIKsy...........sfdEITFSAG...V..GAN......L..RE..AY..VALLNSKSN.GKNMISIY..........................................................................
A0A139X1Y9_9CYAN/298-398             ..........w-FMGDGDEVGKKL....KKMA..nGEN..P...EEE......I....RVFTR.KLR.N.W.G.KD.FYRY..LPSQK.....LGRVIY..AGGDDFLGV.I.----...........------.---....-----................-------...-..---......-..--..--..---------.--------yskkpknpnpaltalewlmtlndkwhehdqkinvsvg.....................................
A0A6F8YIE3_9ACTN/6-120               ...........FLALDGDDIGRRL....ELHM...VME..D...ADG......L....RAFAS.DFA.R.V.L.DQ.LLHY..IDVNP.....LIDMLL..HGGDSLLLT.M.PESE..........iQNVSNF.LHT....SVEGT................GFTFSGG...Y..NNT......M..RG..AY..LALKLAKAT.GKNKIVS-l.........................................................................
I5B4K5_9DELT/331-450                 .........ll--LGDGDNMGKTL....DAIV...T--..-...VDG......H....RAFSA.SLE.S.F.A.SG.IHEI..AESY-.....NGRIVY..SGGDDVLAY.V.PLDSal......scaEA---F.NNL....FFETMekvg........kklkLAPPTFS...L..GMV......I..VH..QR..TPLADALTL.ARQAE---hia.......................................................................
A0A1C0A8F1_9FIRM/336-457             ..........l-IQLDIDNLGDWM....SGNYf.eTGG..L...KEK......Q....QELSE.LII.D.F.S.KR.IKEY..FNDDF.....KGHVVY..AGGDDFLAF.L.PVEYi.........fKAVAEV.RDI....FKELKsnn.........nqfdKLTYSIC...-..-VT......L..AE..VK..IPLSL----.--------vikrtrealel...............................................................
A0A161TUI5_9NOCA/2-116               ...........FAIIDGDDIGPTI....EALL...LSN..D...LNG......F....VERSA.EIT.T.S.I.KL.LARK..LNEIS.....QASLLS..LGGDSMLFE.V.SDVA..........nREFSEF.LHY....WNANC................KVKVSAG...L..GHD......L..QS..AF..LALRMAKST.GKQRVITF..........................................................................
A0A367QYT4_9NOSO/5-121               ...........YAFLDGDNIGERF....LELL...NKN..L...TFE......A....TLLSE.NIK.I.A.I.FE.IDKF..ITSKN.....DISLII..SGGDDVLIK.Y.DYSKy........gtDILEEI.ILL....FKKHT................GLSMSCG...V..GLS......I..EQ..SI..INLDAAKKK.GKNRIE--ns........................................................................
A0A0V7ZSX6_9CYAN/29-145              ..........c-IALDGDKVGTKF....GEFY...RKT..A...SEE......A....TDLST.NLK.S.F.M.LA.LCDL..NTKIGs..sfGDVVKFevAGGDNILIK.Y.SLKEid.......geILAKKI.ANL....FERTI................GIKMSYG...L..GKT......A..FL..AH..CRLRQTKSE.--------vn........................................................................
A0A1H9HC49_9BACT/311-429             ..........i-VHADGDHFGQVI....EG--...LGN..D...RLA......I....ERFSG.QLA.N.F.A.AA.AATV..INDH-.....GGRAIY..IGGDDLLFF.A.PVAYgtk.....tvfDLINAI.DDT....FKEACs..............fTPQPSLS...Y..GVT......L..SH..YK..YPLFEAKSD.SYAA----lera......................................................................
U5QRQ1_9CYAN/254-353                 .........wl--MGDGDKIGNYL....KDLA...RSE..D...GGA......L....RHFSE.AMR.E.W.G.RS.FARD..FAQEK.....LGRVIY..AGGDDFLAV.F.YRPQkkll..pgeviDWLCNF.PKI....WRQHG...............qKVTVSAG...-..---......-..--..--..---------.--------fv........................................................................
A0A1Z4UQF6_9CYAN/277-413             ..........w-FMGDGDEVGKHL....QELA..kKEN..G...DEQ......I....KNFSD.AMR.T.W.G.KQ.FDER..FNLKQ....kIGRIVY..AGGDDFLGI.I.YSNNpqkpispltayEWLLTL.NET....WQKHQ...............qKITVSVG...F..---......-..--..--..---------.--------vwvagsvpqrdvlqhcreaekvakslgrdrvtir........................................
D7BJ36_MEISD/260-371                 .........il--VADGDRMGELI....---A...RQD..D...PDA......H....RGLSK.TLD.D.F.A.KE.ARTI..VPKH-.....RGFMVY..SGGDDVLAL.L.PVNQa.........iACAKEL.SEA....FRHRV................KGTLSAG...V..AIV......H..YRepLS..VSLQNARD-.--------aekaakn...................................................................
A0A0M9E5D6_9DELT/1-75                ..........m-------------....----...---..-...---......-....-----.---.-.-.L.KN.ISEV..MQKQ-.....GGKLIF..CEGDSMLIS.S.----...........DYKMEL.PRK....LLFME................DISFSVG...V..GTS......T..SL..AL..LALKKAKGL.GKKRIETF..........................................................................
A0A0P6YJM1_9CHLR/326-447             ...........LIQFDGDGIGKKI....DYLL..aRDD..A...ENA......H....RRFSQ.NIG.A.F.S.NA.VRGT..INPNQ.....GGFLIY..NGGDDVLLL.A.SLERg.........lQLAIEL.ART....YQEMVgd...........gfnGFTATAS...A..GIV......I..AH..HL..TPLSKALTL.LRSAER--ra........................................................................
A0A3N6PLR1_9CYAN/241-300             ...........YFGFDGDFRGDYL....EMAF...EKS..N...EDE......V....RERSH.IVH.E.V.I.GE.LKKL..IYKATkvyflQKEII-..---------.-.----...........------.---....-----................-------...-..---......-..--..--..---------.--------fyl.......................................................................
A0A7U9PTB1_9CHLR/325-446             ...........LIQFDGDGVGAKI....DHLLe.nKEK..A...EAN......H....RCFSE.NIA.R.F.S.NQ.VRKV..VKPEA.....GGFLIY..NGGDDVLFL.A.SREKg.........lELARKL.AEE....YQNTVgk............dlGILATAS...A..GVV......I..AH..HL..TPLARALSL.LHEA----eksa......................................................................
A0A2P7TSS7_9SPHI/345-482             .........vl--SFDGDNMGKIM....TGSF...LKP..D...KQNeyllpfQ....KETSR.LLT.E.F.A.RK.VTEI..VKFP-.....QGKVVY..AGGDDCLAL.I.NLNHl.........yNVLLQV.QGE....FHRTVnsplqqtfadvlkpgfNFTFSAG...I..AIA......H..YK..TPlgITLQKAHS-.--------lqntaket..................................................................
A0A6C2D553_9RHOO/3-117               ...........YLTIDGDDVGQQI....TKFY...LNN..D...EKS......L....SNLND.LMG.K.T.T.QL.ISAY..LNSI-.....GFAVIF..CGADGVAGF.A.QYLE...........VSESNI.FKE....ISALGe..............gCATFSVG...V..GCT......L..RE..SY..IALMSAKSA.GKAQLHN-y.........................................................................
A0A1M6LSY5_9CLOT/291-413             ..........i-YRFDIDNLGKWM....NGKYk.dSKE..N...LKD.....yQ....QELSN.KIN.E.F.F.EK.VLKF..FDENE.....NNTLVY..AGGDDLLAL.L.NVKDa.........fKFSKEI.EEE....FNKILkknn........nkfkKLTFSQG...I..---......-..--..--..---------.--------fiihykdtlkeslkvskerle.....................................................
A0A0F5Y8L0_9CYAN/385-502             ...........YFGFDGDATGKYL....EIAFg.dLLE..D...EEE......V....LRRSK.SIT.E.S.I.KQ.MRKI..ICGETk...nPKSVIF..AEGDNILFK.S.KYNS...........DLLRTI.QNK....YTEIT................GLSSSIG...Y..GKT......L..KE..AT..IALRLAKAR.KGNSVVG-v.........................................................................
A0A367RV09_9NOSO/5-121               ...........YLAADGDDVGRKI....EFFI...VTN..Q...MEL......L....SNFFH.NFQ.S.A.M.AW.LAKR..LSDEF.....NAKIIF..NGGDSLLVS.L.QVDDi........svTKLENL.RIQ....FSSLS................EATLSFG...L..GNN......P..RQ..AY..FALKLAKAS.GKNRIEIF..........................................................................
A0A0D0S9W7_9FIRM/103-213             ..........v-VQADGDSVGKYL....GSLI...SDE..K...V--......-....KGFSE.RCL.K.Y.T.QE.AAEL..IKNF-.....SGVVIY..AGGDDLLFI.C.PLEHn.........sKTIFEL.CKD....IRDRFndkfk.....gdgvnvDLTVSFG...I..SIN......-..--..--..---------.--------yykfplyeal................................................................
A9AVY9_HERA2/348-467                 ..........i-IAADGDKMGNLI....DSI-...--S..D...VQI......H....RDLSK.VVT.T.F.A.KD.AAQI..LENDY.....QAAVIY..AGGDDVLAL.L.PLHTllaa..tkkisDLFIEY.MQP....LAEQQ...............aVSTPTLS...V..GVA......I..VH..HL..EALQDSI--.--------qlarkaekl.................................................................
B1I5L0_DESAP/328-449                 .........ll--LADGDHVGKVI....DT--...-QE..T...PEK......H....QELSR.SQS.R.F.A.LE.VRDI..VQHH-.....QGSLLY..SGGDDVLAL.V.PLHTv.........lACARSL.AET....FRQRFagfka......edggkEISLTLS...V..GIA......V..VH..HL..DPLSDALEL.ARRA----ekaa......................................................................
A0A3M0BR48_9AQUI/388-515             .........vl--LMDGDNMGKKI....SKL-...--E..T...EEK......Q....KELSK.YLS.E.F.T.KK.VKGI..VEKNH.....KGFLVY..AGGDDVLAL.L.PVQSa.........lDCANEI.QKE....FNQDLnkkikdk.yfpnekdlDYHFTMS...A..GLI......L..AH..HR..LPLNYVLSE.VRNAE---ska.......................................................................
A0A2H5YTS1_9BACT/337-452             .........vv--VLDGDSMGKRI....NELL..tGQD..S...PEA......H....RAFSQ.RLA.E.F.A.GA.VRAL..EREFK.....QVEVVY..NGGDDVLAL.A.PA--...........QLALDF.ARLaaerFQEIT................KGTASAG...I..--A......V..AH..WL..QPLGDALKA.--------arqaeerak.................................................................
A0A1H3PQD3_9CLOT/295-411             .........vl--LMDGDNMGKWF....SK--...-SN..K...IED......H....QELSK.RLAfY.A.S.ET.VPKT..VEKDH.....GGKLVY..AGGDDVLAF.L.PLQSa.........fQCAKEL.RMA....FGSDQq.............gfAQGATAS...M..GMV......I..TH..DK..APLSKV---.--------lrqvrrmekta...............................................................
A0A2K2TT40_9CLOT/309-418             ..........l-VKFDGDDMGT--....-HFL...SKE..D...ENG......Q....RELSE.RIG.D.F.A.KQ.VPRI..FREH-.....GGLPVY..AGGEDFFGY.L.PV--...........NTLFDC.IMA....MRQVFq..............fKIEGTFS...A..GIA......V..AH..VM..QPLKEVAAL.ANEMV---kka.......................................................................
K9PDQ1_9CYAN/274-373                 ..........w-FMGDGDEVGKHL....QKLA..aLPN..G...DEE......L....KKFSQ.AMR.N.W.G.KD.FNRD..FPKE-.....IGRVVY..AGGDDFLGA.I.YRDK...........------.---....-----................-------...-..---......-..--..--..---------.--------dqepitakqaftwlsqlpkewekhqqkiglsvg.........................................
A0A165YSQ2_9BACI/284-394             ..........i-LLMDGDNMGK--....--WF...SGE..N...KED......Y....SRVSE.RLA.H.F.S.QR.VVPK..IVERD....yKGRLVY..AGGDDVLAF.L.PVEEa.........lSVAQKL.RFA....FSHPEh.............glGEKATAS...I..GL-......-..--..--..---------.--------iighkkaplqsllnnvrq........................................................
A0A1W9QCR8_9DELT/332-451             .........cl--VADGDRMGRAI....NEL-...--D..S...AAA......H....RAFSK.ALA.G.F.A.DA.ARNV..VEQQY.....RGALVY..AGGDDVLAF.V.SLPEalac...adalR-----.-TA....FESAMatacas...laadkrpTLSVGLG...I..GHV......M..--..--..---------.--------esmgdlltlgrqaer...........................................................
A0A1X7LP33_9BACL/358-476             ...........FLVADGDRMGDLL....DTLT...S--..-...YQE......H....QRVSE.QLS.H.F.S.VR.AEAI..VKEH-.....SGELIY..SGGDDVMAY.V.SLNEffk.....lseSLSREF.QHV....MKQVVp.............kgCTKPTLS...V..GVA......I..VH..ML..EPLEDVRNL.AKQAE---rma.......................................................................
C8PFL6_9PROT/265-382                 .........vl--KADVDGMGDFI....KNSN...VTN..S...FDS......F....DMFSK.GLD.S.FfS.IY.IPRL..IKQNF....pHTYIVF..SGGDDLLLV.G.AW--...........DTVLDI.ARF....IDDEFkk...........fisDKTLSLS...M..GIC......I..AK..PS..VPIKY----.--------laelsenqlel...............................................................
A0A1M5A1B6_9BACL/361-472             ..........l-LMMDGDRLGQLL....QTK-...-SK..E...PNQ......S....KKISE.ALA.L.F.T.DQ.IAKQ..INDF-.....HGVTIY..AGGDDVLAL.F.PLAQa.........iPAAVHL.REK....YIQSFqq...........sgsQLQSTIS...A..GIV......Y..AH..KM..APLQN----.--------ivqygh....................................................................
A0A3N1AX98_9ACTN/6-120               ...........FLALDGDDIGRRL....ELYM...LTE..N...LHD......L....QTFAR.DFS.Q.T.V.SR.VVQS..LQLTP.....DVDIIL..GSGDSILAR.L.PQRE..........iERSISL.VKQ....ATANT................GFSFSGG...Y..AET......M..QG..AY..LALKVAKST.GKNRII--pa........................................................................
A0A251WM42_9CYAN/279-413             ..........w-FMGDGDSVGDKL....KELA..kNPN..D...VQP......L....KTFSN.AMR.K.W.G.QD.FKHN..FPKN-.....LGRVIY..AGGDDFLGV.I.YSKDpkaaipenqalQWLMGL.NQQ....WQAHG...............qPITLSVGfvwA..GHSvpqrdvL..QH..CR..EAEKRAKTL.GKNRV---tir.......................................................................
A0A1Z4J2K6_9CYAN/7-123               ..........m-CIGDGDNIGDVI....DFYL...LSQ..N...LEE......A....SKFSF.QVK.A.A.I.EH.IAEL..AENEI.....NASVVY..VAGDDICFM.V.PANLn........imNSLVSY.SEF....FLVTT................GKTMSFG...V..GKT......S..VE..AL..ISLRKAKVS.GKGRVVTF..........................................................................
#=GC seq_cons                        ..........h.hhhDGDshGchl....pthh....ps..s....cp......h....pchSc.pls.p.a.s.pp.lpch..lppp......pupllY..uGGDDlLuh.h.shpp..........hphh.pl.tph....apphh................shohShu...h..Ghs......h..hc..hh...sLt.sh...........h.........................................................................
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