#=GF ID   ssDNA_DBD
#=GF AC   PF18333.5
#=GF DE   Non-canonical single-stranded DNA-binding domain
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF03278
#=GF GA   25.00 25.00;
#=GF TC   29.30 29.30;
#=GF NC   24.80 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   22106294
#=GF RT   Displacement of the canonical single-stranded DNA-binding
#=GF RT   protein in the Thermoproteales.
#=GF RA   Paytubi S, McMahon SA, Graham S, Liu H, Botting CH, Makarova KS,
#=GF RA   Koonin EV, Naismith JH, White MF;
#=GF RL   Proc Natl Acad Sci U S A. 2012;109:E398-E405.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in ThermoDBP, a non-canonical
#=GF CC   single-stranded DNA-binding protein in Thermoproteales.
#=GF CC   Single-stranded DNA-binding proteins are needed for DNA
#=GF CC   metabolism, sequestering and protecting transiently formed ssDNA
#=GF CC   during DNA replication and recombination, detecting DNA damage
#=GF CC   and recruiting repair proteins. The outer edge of the
#=GF CC   ssDNA-binding cleft, formed by this domain, has a strongly
#=GF CC   positive electrostatic surface potential because of the
#=GF CC   conserved basic residues R49, K54, R65, R80, R86, R90, K97, and
#=GF CC   R112 [1].
#=GF SQ   19
#=GS S1NLE9_9ENTE/284-388      AC S1NLE9.1
#=GS Q3Y0W3_ENTFD/282-387      AC Q3Y0W3.1
#=GS A0A377KHD2_9ENTE/284-389  AC A0A377KHD2.1
#=GS R2SAN4_9ENTE/283-385      AC R2SAN4.1
#=GS A0A179EPX9_ENTTH/285-390  AC A0A179EPX9.1
#=GS A0A6I2GG35_9LACT/196-301  AC A0A6I2GG35.1
#=GS A0A430B241_9ENTE/122-226  AC A0A430B241.1
#=GS A0A242K0K8_9ENTE/283-388  AC A0A242K0K8.1
#=GS S0S7Q5_ENTAV/285-390      AC S0S7Q5.1
#=GS A0A430B0U5_9ENTE/287-391  AC A0A430B0U5.1
#=GS C9A783_ENTCA/284-388      AC C9A783.1
#=GS R2QHH1_9ENTE/283-385      AC R2QHH1.1
#=GS T0U4B7_9ENTE/284-389      AC T0U4B7.1
#=GS A0A1L8RGR7_9ENTE/282-384  AC A0A1L8RGR7.1
#=GS A0A4D7CP26_9ENTE/286-391  AC A0A4D7CP26.1
#=GS R3TVC8_9ENTE/283-385      AC R3TVC8.1
#=GS A0A242K1Y7_9ENTE/286-390  AC A0A242K1Y7.1
#=GS Q82ZN7_ENTFA/285-390      AC Q82ZN7.1
#=GS A0A1L8TN14_9ENTE/285-390  AC A0A1L8TN14.1
S1NLE9_9ENTE/284-388                 ....NYHDLTVRTQQFVLQWSQDFQLPALADTHLAENLMLLLLKYNESPDLADKFEADYQQ-SPPQKATFATLQEDNLRLLQQDFA.ETKENKPVYLLHLIMLLQQQAFFS..
Q3Y0W3_ENTFD/282-387                 ....HHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDRQYHRFLETYDQQYAHLYQQKENLLNDLKK.EIEINEPNYFLQLLSLLIQQTIFS..
A0A377KHD2_9ENTE/284-389             .syp----FSTSIQAFVQELADHLSLSSLRHTKLSHNLILMLLKYHESPLLMEQLQSQYHYFVEEYETNYTDLYPYKVRLLEKIKTpALPINDETYFFYLLSLLTQQALLA..
R2SAN4_9ENTE/283-385                 ...s-YGHLFQNARDYLASLTEGRALV--ENQELLEDLVLFQVKYYESKSLTDQFLGEYEEVLSVCQARFPQLFQSVATSLAAGQL.SGITEVSNHAVSNLVLLIQTA---ka
A0A179EPX9_ENTTH/285-390             ...d-YPNLLEKAQETVQKLAEKLNLPKLHETHLKCNLLILLLKYAESPSLSEQFQLEYQELLIQQNEAYPIVQMIGEELFQELLK.VASIKEQAYFVNIFLLLCQQAIFS..
A0A6I2GG35_9LACT/196-301             ....HYSVLLEKSRLFVHSLSEHYQLPALNNSQLTENITLFLIKYFESRRLLDKFLMEYHDVLVVVQAKFPQLYQWVQEEMRNYRF.AGILKASEYANSTAVLLIQTAIYQ..
A0A430B241_9ENTE/122-226             ....NYYDMNERCTRAVYRIGEAIEQPKLFTTNLNENLFLFFLKYHESKQLSDIFS-ESQDILDIGYHRFLSIYTYVFEEIEKSDL.LENLPRSNYIVNTATLLIQEAIM-k.
A0A242K0K8_9ENTE/283-388             qnyp----FSSDIKEFATLLAHLLDLEDLKKTKLVDNLILLLLKYHESPVLMEQVTLQYRYYLEEYEHQYTQLYPFKQELLAKLKK.YLPIQNDDYFLHVLSLLIQQAILA..
S0S7Q5_ENTAV/285-390                 ...d-YPLLREKAQQIVQEIADRLNLQELLQTNLQTNLLLLLLKYAESPALSEQFQLEYQELLLQRHEEYAFLNEKSMALFNSLPQ.FSTIEDTSYFVNLFSLLSQQAIF-t.
A0A430B0U5_9ENTE/287-391             ....HYQHLISYCDATAGKISAHLGKT-VNLTALTDGLLLFFLKYAESHILADRFLLEHQELIEFSQDKFPELFQFIDHLINHSNS.IIRVADSAPVVSTLLLITQDALLS..
C9A783_ENTCA/284-388                 ....SYKTIYQKTTHFVGKLDRLLQLSLASDTQLIENLLLLLIKSQESAKLSELFGLEFHE-IQRLNQPYSLPIEATIHDFLEEQT.ASQSEMSFPLWSTTTLLIQQAILQ..
R2QHH1_9ENTE/283-385                 ....HYPTLAAVAAQLTEQVANQTQIS-LQQSQLAENLLLLLLKYSESTWLSEQFQLEYQELLTERKNDDRY--RSDEELLPILQP.ILQLDNPVYLLNLIALLEQQALFA..
T0U4B7_9ENTE/284-389                 ...a-YQEIKQSVQRFVQELGQELAIPLLSETQLADNLLLLVLKFNESAKLSEQFQLEYQEMMHIRQHNYQAIFERLRKFILDPKF.AIVTDEPKYILNMASLLVQQAVLQ..
A0A1L8RGR7_9ENTE/282-384             ....QYQLLAETLADFVADLARITQAN-LAATALADNLLLLLLKYQESPELSAQFEADYQG-INAKRVVASPFYSQNLALLTAQLT.DSK-ARPSYLLHLMTLLQQQALFA..
A0A4D7CP26_9ENTE/286-391             ...n-YGEIFDHSVALTKKISHSLQIPALNDTDLSRNIALLFLKYYESAELFQQFLSEYPELLNMELNHSETLKDLLRETFSREAP.YSEWNLSEHIVDNLILLINEAL--st
R3TVC8_9ENTE/283-385                 ....MYPTLYSVADQLTQQVICRSNIP-LQESKLTENLTLLLLKYNESTLLSQQFQLEYQELLTDRKQSDRH--QNDEEILTIIQD.TVHLENPAYLMNLISLLEQQALFA..
A0A242K1Y7_9ENTE/286-390             ....NYDVLFSTCQEFIQRLSAKLNQPALNTAYLLDNLVLFLLKYYESRRLSDKFLMEYQELFPFSRKRFPELYQLIYDEIAY-YD.LAYLPRSNYVVNTVTLLVQEAR--yl
Q82ZN7_ENTFA/285-390                 ....HYSQLRKSLQQFVTNLSTEEARPDLIQTNLLDNLLLLFIKYTESPTLSEQFQLEYQELMTEQAAEDLALSKSNQELLEILSR.YTTIEEPTYFLSLASLLEKQAIYS..
A0A1L8TN14_9ENTE/285-390             ...d-YSQLLTSATKTVQEIAEEFHLPQLVTTSLTENVLLLLLKYAESPALSKQFQLEYHELINQHKDEHRFLYQIGLTLFEQLPQ.FSSSEDTTYFINLFSLLTQQAIVS..
#=GC seq_cons                        .....YtpLhppspphVpclupchplstLppTpLs-NLlLLLLKYtESstLo-QFphEYpEllp.ppppastLhphs.cllpp.pp.hsplpcssYhlshhoLLhQQAlht..
//