KEGG T00014: PH1155

Pyrococcus horikoshii: PH1155

Entry

PH1155            CDS       T00014

Symbol

PH1155

Name

(GenBank) 446aa long hypothetical thiamine biosynthesis protein

K21219

hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]

Organism

pho Pyrococcus horikoshii

Pathway

pho00730

Thiamine metabolism

pho01100

Metabolic pathways

pho01240

Biosynthesis of cofactors

Module

pho_M00899

Thiamine salvage pathway, HMP/HET => TMP

Brite

KEGG Orthology (KO) [BR:pho00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    PH1155 (PH1155)
Enzymes [BR:pho01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     PH1155 (PH1155)
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     PH1155 (PH1155)
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     PH1155 (PH1155)

SSDB

Motif

Pfam:

Phos_pyr_kin ThiP_synth PfkB HK Carb_kinase

Other DBs

NCBI-ProteinID:

BAA30255

UniProt:

O58879

Position

complement(1048666..1050006)

AA seq 446 aa
MRLVRTALTIAGSDSGGGAGIEADLKTFTAFGVHGLVAITSVTAQNTQTVTAIHDIPPEV
VSEQIRVVAEDIGVDAAKTGMLSNAEIIKAVAKTVKNYDFPLVVDPVMIAKSGAPLLRED
AVDALIKYILPLATLVTPNRFEAEKLTGMEIRNVNDAKLAAKKIAEETGAKAVIVKGGHL
EGKEAIDVLYHNGAYKLYRAPKVDGCTHGTGCSFSAAITANLAKGLSLEDAVSVAKEFIT
LGISTGHKIGHGHCPVNQSAWIEIPAEKWRIYEELTRAVREFERINPIKLIPEVGTNFVY
ALPFPYARTKEDVAGVKGRIVRVGNEVRAVGSVEFGASDHLARAILTFMRFYPKYRSAIN
VRYSEEIVELAKEQGFTVSFYDRREEPIEVKEKEGATIPWGIEVAVKRINKRPDVIYHLG
DIGKEPMILIFGRNPREVLDKLRLLI

NT seq 1341 nt +upstreamnt +downstreamnt
atgagacttgttagaacagctctgactatagctggaagtgatagtggaggtggggcagga
attgaagccgatctaaagacgtttacggcctttggagttcacggattagtcgcgataacc
tccgtaacggcccagaacacacagaccgtaactgctattcatgacattcctcccgaggtt
gtttcagaacagataagggttgttgcggaggatataggtgttgatgctgcaaagacggga
atgttaagcaatgctgagatcataaaggccgtagcaaagacagtgaaaaactatgatttt
cctttagtcgtcgatccagtaatgatcgctaaaagtggtgctcctctccttagggaagat
gccgtggatgcattaattaagtatattcttccacttgcaacccttgtaactcctaatagg
tttgaggccgagaagcttaccggtatggagattaggaatgtaaatgacgccaagctagcg
gcaaagaagattgcagaagaaacaggagctaaagctgttatagttaagggcgggcacttg
gaaggaaaggaagccatagatgtcctctatcataatggagcttacaagctttatagggcc
cccaaagttgatgggtgtactcatggaacgggatgtagcttttcggccgcgattaccgct
aacttagctaaaggtttaagcttagaagatgccgtaagcgttgcgaaggagttcatcact
ctaggaatatcaactggtcataaaattggacatggccactgcccagtcaatcaatcagct
tggatagagattccagcggagaaatggaggatctatgaagagcttacaagagctgttagg
gagtttgagaggataaaccctataaagctaattccagaggttggaacaaacttcgtttat
gccctcccgtttccgtatgcaagaaccaaggaagacgttgcaggtgttaagggaaggata
gtcagggtagggaatgaagtcagggccgtgggttcggtggaatttggggcaagcgatcat
ttagcaagggccattttgactttcatgaggttctacccgaagtatagaagtgctataaat
gttagatattccgaggaaattgtagagctcgcaaaagagcagggattcactgtgtcattt
tacgatagaagggaggagccgattgaagttaaggagaaggagggagcaactataccatgg
ggaatcgaagttgcggtaaagaggattaacaaaaggcccgatgtaatatatcatctgggc
gatattgggaaggagcccatgatattaatctttggcaggaatcccagggaagtgctcgat
aagcttaggttgctaatctaa

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