KEGG   Pan paniscus (bonobo): 100973863
Entry
100973863         CDS       T02283                                 
Symbol
NRG1
Name
(RefSeq) pro-neuregulin-1, membrane-bound isoform isoform X3
  KO
K05455  neuregulin 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04012  ErbB signaling pathway
pps05014  Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100973863 (NRG1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100973863 (NRG1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100973863 (NRG1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pps04052]
    100973863 (NRG1)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100973863 (NRG1)
Cytokines and neuropeptides [BR:pps04052]
 Cytokines
  Growth factors (RTK binding)
   100973863 (NRG1)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100973863 (NRG1)
SSDB
Motif
Pfam: Neuregulin I-set ig Ig_3 Ig_2 V-set EGF DUF6377 Ig_6 Cyt_b-c1_8 DUF973
Other DBs
NCBI-GeneID: 100973863
NCBI-ProteinID: XP_003830804
Ensembl: ENSPPAG00000029556
UniProt: A0A2R9A6B4
Position
8:30954852..32084411
AA seq 645 aa
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEA
EELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANG
PHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSW
SNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSY
RDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFVEEE
RPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQ
EPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPL
AASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV
NT seq 1938 nt   +upstreamnt  +downstreamnt
atgtccgagcgcaaagaaggcagaggcaaagggaagggcaagaagaaggagcgaggctcc
ggcaagaagccggagtccgcggcgggcagccagagcccagccttgcctccccgattgaaa
gagatgaaaagccaggaatcggctgcaggttccaaactagtccttcggtgtgaaaccagt
tcggaatactcctctctcagattcaagtggttcaagaatgggaatgaattgaatcgaaaa
aacaaaccacaaaatatcaagatacaaaaaaagccagggaagtcagaacttcgcattaac
aaggcatcactggctgattctggagagtatatgtgcaaagtgatcagcaaattaggaaat
gacagtgcctctgccaatatcaccatcgtggaatcaaatgagatcatcactggcatgcca
gcctcaactgaaggagcatatgtgtcttcagagtctcccattagaatatcagtatccaca
gaaggagcaaatacttcttcatctacatctacatccaccactgggacaagccatcttgta
aaatgtgcggagaaggagaaaactttctgtgtgaatggaggggagtgcttcatggtgaaa
gacctttcaaacccctcgagatacttgtgcaagtgcccaaatgagtttactggtgatcgc
tgccaaaactacgtaatggccagcttctacaagcatcttgggattgaatttatggaggcg
gaggagctgtaccagaagagagtgctgaccataaccggcatctgcatcgccctccttgtg
gtcggcatcatgtgtgtggtggcctactgcaaaaccaagaaacagcggaaaaagcttcat
gaccgtcttcggcagagccttcggtctgaacgaaacaatatgatgaacattgccaatggg
cctcaccatcctaacccaccccccgagaatgtccagctggtgaatcaatacgtatctaaa
aacgtcatctccagtgagcatattgttgagagagaagcagagacatccttttccaccagt
cactatacttccacagcccatcactccactactgtcacccagactcctagccacagctgg
agcaacggacacactgaaagcatcctttccgaaagccactctgtaatcgtgatgtcatcc
gtagaaaacagtaggcacagtagcccaactgggggcccaagaggacgtcttaatggcaca
ggaggccctcgtgaatgtaacagcttcctcaggcatgccagagaaacccctgattcctac
cgagactctcctcatagtgaaaggtatgtgtcagccatgaccaccccggctcgtatgtca
cctgtagatttccacacgccaagctcccccaaatcgcccccttcggaaatgtctccaccc
gtgtccagcatgacagtgtccatgccttccatggcggtcagccccttcgtggaagaagag
agacctctacttctcgtgacaccaccaaggctgcgggagaagaagtttgaccatcaccct
cagcagttcagctccttccaccacaaccccgcgcatgacagtaacagcctccctgctagc
cccttgaggatagtggaggatgaggagtatgaaacgacccaagagtacgagccagcccaa
gagcctgttaagaaactcgccaatagccggcgggccaaaagaaccaagcccaatggccac
attgctaacagattggaagtggacagcaacacaagctcccagagcagtaactcagagagt
gaaacagaagatgaaagagtaggtgaagatacgcctttcctgggcatacagaaccccctg
gcagccagtcttgaggcaacacctgccttccgcctggctgacagcaggactaacccagca
ggccgcttctcgacacaggaagaaatccaggccaggctgtctagtgtaattgctaaccaa
gaccctattgctgtataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (11)   
   Pfam (11)   
All databases (64)   

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